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Search of human proteins with 22749341
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22749341 hypothetical protein LOC199870 isoform 3 [Homo
sapiens]
(307 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22749341 hypothetical protein LOC199870 isoform 3 [Homo sapiens] 630 0.0
gi|219881536 hypothetical protein LOC199870 isoform 1 [Homo sapi... 611 e-175
gi|219881540 hypothetical protein LOC199870 isoform 4 [Homo sapi... 560 e-160
gi|219881538 hypothetical protein LOC199870 isoform 2 [Homo sapi... 541 e-154
gi|134288896 hypothetical protein LOC143684 [Homo sapiens] 449 e-126
gi|221139693 hypothetical protein LOC199870 isoform 5 [Homo sapi... 402 e-112
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 46 5e-05
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 44 2e-04
gi|146229340 mutated in colorectal cancers isoform 1 [Homo sapiens] 42 7e-04
gi|4505129 mutated in colorectal cancers isoform 2 [Homo sapiens] 42 7e-04
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 42 7e-04
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 41 0.002
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 41 0.002
gi|4885583 Rho-associated, coiled-coil containing protein kinase... 40 0.002
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 40 0.002
gi|117414154 sodium channel associated protein 2 isoform b [Homo... 40 0.002
gi|117414162 sodium channel associated protein 2 isoform a [Homo... 40 0.002
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 40 0.003
gi|14195601 protein phosphatase 1, regulatory (inhibitor) subuni... 40 0.003
gi|14195599 protein phosphatase 1, regulatory (inhibitor) subuni... 40 0.003
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 40 0.003
gi|4758648 kinesin family member 5B [Homo sapiens] 39 0.004
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 39 0.006
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 39 0.008
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 39 0.008
gi|35038601 spindle assembly abnormal protein 6 [Homo sapiens] 39 0.008
gi|157785668 coiled-coil domain containing 39 [Homo sapiens] 39 0.008
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 38 0.010
gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 38 0.010
gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 38 0.010
>gi|22749341 hypothetical protein LOC199870 isoform 3 [Homo sapiens]
Length = 307
Score = 630 bits (1625), Expect = 0.0
Identities = 307/307 (100%), Positives = 307/307 (100%)
Query: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQ 60
MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQ
Sbjct: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQ 60
Query: 61 NVQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVD 120
NVQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVD
Sbjct: 61 NVQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVD 120
Query: 121 GKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSI 180
GKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSI
Sbjct: 121 GKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSI 180
Query: 181 QNEIPKKKSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMIL 240
QNEIPKKKSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMIL
Sbjct: 181 QNEIPKKKSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMIL 240
Query: 241 EKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEK 300
EKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEK
Sbjct: 241 EKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEK 300
Query: 301 SGAITSP 307
SGAITSP
Sbjct: 301 SGAITSP 307
>gi|219881536 hypothetical protein LOC199870 isoform 1 [Homo
sapiens]
Length = 341
Score = 611 bits (1575), Expect = e-175
Identities = 306/341 (89%), Positives = 306/341 (89%), Gaps = 34/341 (9%)
Query: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQES----------- 49
MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQE
Sbjct: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQERLECNGTISAHC 60
Query: 50 -----------------------KTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNKCQ 86
KTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNKCQ
Sbjct: 61 NLHLPGSSDSPASSSRVAGITGIKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNKCQ 120
Query: 87 RCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHL 146
RCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHL
Sbjct: 121 RCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHL 180
Query: 147 SSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSIQNEIPKKKSKFESITTNGDSFSPDLA 206
SSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSIQNEIPKKKSKFESITTNGDSFSPDLA
Sbjct: 181 SSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSIQNEIPKKKSKFESITTNGDSFSPDLA 240
Query: 207 LDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQ 266
LDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQ
Sbjct: 241 LDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQ 300
Query: 267 MEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEKSGAITSP 307
MEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEKSGAITSP
Sbjct: 301 MEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEKSGAITSP 341
>gi|219881540 hypothetical protein LOC199870 isoform 4 [Homo
sapiens]
Length = 278
Score = 560 bits (1443), Expect = e-160
Identities = 278/307 (90%), Positives = 278/307 (90%), Gaps = 29/307 (9%)
Query: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQ 60
MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQ
Sbjct: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQ 60
Query: 61 NVQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVD 120
NVQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVD
Sbjct: 61 NVQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVD 120
Query: 121 GKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSI 180
GKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNS
Sbjct: 121 GKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNS--------- 171
Query: 181 QNEIPKKKSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMIL 240
FSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMIL
Sbjct: 172 --------------------FSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMIL 211
Query: 241 EKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEK 300
EKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEK
Sbjct: 212 EKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEK 271
Query: 301 SGAITSP 307
SGAITSP
Sbjct: 272 SGAITSP 278
>gi|219881538 hypothetical protein LOC199870 isoform 2 [Homo
sapiens]
Length = 312
Score = 541 bits (1393), Expect = e-154
Identities = 277/341 (81%), Positives = 277/341 (81%), Gaps = 63/341 (18%)
Query: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQES----------- 49
MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQE
Sbjct: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQERLECNGTISAHC 60
Query: 50 -----------------------KTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNKCQ 86
KTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNKCQ
Sbjct: 61 NLHLPGSSDSPASSSRVAGITGIKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNKCQ 120
Query: 87 RCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHL 146
RCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHL
Sbjct: 121 RCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHL 180
Query: 147 SSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSIQNEIPKKKSKFESITTNGDSFSPDLA 206
SSSSRAGHQEKEQYSRLSGGGHYNS FSPDLA
Sbjct: 181 SSSSRAGHQEKEQYSRLSGGGHYNS-----------------------------FSPDLA 211
Query: 207 LDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQ 266
LDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQ
Sbjct: 212 LDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQ 271
Query: 267 MEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEKSGAITSP 307
MEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEKSGAITSP
Sbjct: 272 MEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEKSGAITSP 312
>gi|134288896 hypothetical protein LOC143684 [Homo sapiens]
Length = 339
Score = 449 bits (1154), Expect = e-126
Identities = 228/336 (67%), Positives = 263/336 (78%), Gaps = 30/336 (8%)
Query: 2 AALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQN 61
+ALYACTKC QR+PFE LSQGQQLCKECRIAHP+VKCTYCR+E+QQESKTNTICKKCAQN
Sbjct: 4 SALYACTKCTQRYPFEELSQGQQLCKECRIAHPIVKCTYCRSEFQQESKTNTICKKCAQN 63
Query: 62 VQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQCKQQCAFDRKDD-RKKVD 120
V+ +GTPKPCQYCNIIAAFIG KCQRCTNSEKKYGPP +CEQCKQQCAFDRK++ R+KVD
Sbjct: 64 VKQFGTPKPCQYCNIIAAFIGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKEEGRRKVD 123
Query: 121 GKLLCWLCTLSYKRVLQKTKEQRKHL----SSSSRAGHQEKEQYSRLSGGGHYN------ 170
GKLLCWLCTLSYKRVLQKTKEQRK L S+SS + EK+Q+ H++
Sbjct: 124 GKLLCWLCTLSYKRVLQKTKEQRKSLGSSHSNSSSSSLTEKDQHHPKHHHHHHHHHHRHS 183
Query: 171 ------------------SQKTLSTSSIQNEIPKKKSKFESITTNGDSFSPDLALDSPGT 212
Q S+++IQNE PKKK K ES +NGDS S + + DS GT
Sbjct: 184 SSHHKISNLSPEEEQGLWKQSHKSSATIQNETPKKKPKLESKPSNGDSSSINQSADSGGT 243
Query: 213 DHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHK 272
D+FV+I+QLKEEV +LK++L Q+DQ ILEK+KK+TELKADFQYQES +R KMN MEK HK
Sbjct: 244 DNFVLISQLKEEVMSLKRLLQQRDQTILEKDKKLTELKADFQYQESNLRTKMNSMEKAHK 303
Query: 273 EVTEQLQAKNRELLKQAAALSKSKKSEKSGAI-TSP 307
E EQLQAKNRELLKQ AALSK KK +KSG+I TSP
Sbjct: 304 ETVEQLQAKNRELLKQVAALSKGKKFDKSGSILTSP 339
>gi|221139693 hypothetical protein LOC199870 isoform 5 [Homo
sapiens]
Length = 227
Score = 402 bits (1032), Expect = e-112
Identities = 219/307 (71%), Positives = 222/307 (72%), Gaps = 80/307 (26%)
Query: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQ 60
MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICK
Sbjct: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICK---- 56
Query: 61 NVQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVD 120
+C + + YG VD
Sbjct: 57 --------------------------KCAQNVQLYGT---------------------VD 69
Query: 121 GKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSI 180
GKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNS
Sbjct: 70 GKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNS--------- 120
Query: 181 QNEIPKKKSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMIL 240
FSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMIL
Sbjct: 121 --------------------FSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMIL 160
Query: 241 EKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEK 300
EKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEK
Sbjct: 161 EKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEK 220
Query: 301 SGAITSP 307
SGAITSP
Sbjct: 221 SGAITSP 227
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 45.8 bits (107), Expect = 5e-05
Identities = 39/178 (21%), Positives = 83/178 (46%), Gaps = 31/178 (17%)
Query: 136 LQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSIQNEIPKKKSKFESIT 195
L K E K + SS+R Q+K + + SI+ ++ K++ + + +
Sbjct: 770 LSKQLEMEKEIVSSTRLDLQKKSE----------------ALESIKQKLTKQEEEKQILK 813
Query: 196 TNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILE------KEKKITEL 249
+ ++ S + + H + +++ V L+K+ +K+ ++ E K K+++
Sbjct: 814 QDFETLSQETKIQ-----HEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDS 868
Query: 250 ----KADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEKSGA 303
K++F+ + + +A + +EKT KE+ QLQ + LK+ L KS + EK +
Sbjct: 869 LKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEAS 926
Score = 37.4 bits (85), Expect = 0.017
Identities = 42/184 (22%), Positives = 90/184 (48%), Gaps = 24/184 (13%)
Query: 135 VLQKTKEQRKHLSSSSRAGHQ---EKEQYSRLSGGGHYNSQKTLSTSSIQNEIPKKKSKF 191
VLQKT+ + K ++A + EKE+ S L + SQ+T +Q++ ++S+
Sbjct: 986 VLQKTELENKLQQQLTQAAQELAAEKEKISVLQNN-YEKSQETFK--QLQSDFYGRESEL 1042
Query: 192 ESITTNGDSFSPDLALDSPGT--------DHFVIIAQLKEEVATLKKMLHQKDQMILEKE 243
+ + S L+L + +I +LK ATL++ +K+Q + E+
Sbjct: 1043 LATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERC 1102
Query: 244 KKITELKADFQYQESQM---RAKMNQME----KTHKEVT---EQLQAKNRELLKQAAALS 293
K + +++ + +E ++ ++K+ ++E + KE+T E+L++ E +K+ L
Sbjct: 1103 KALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLK 1162
Query: 294 KSKK 297
+K+
Sbjct: 1163 DAKQ 1166
Score = 33.9 bits (76), Expect = 0.19
Identities = 40/185 (21%), Positives = 80/185 (43%), Gaps = 19/185 (10%)
Query: 135 VLQKTKE-------QRKHLSSSSRAGHQEKEQYSRLSGGGH-YNSQKTLSTSSIQNEIPK 186
+LQK+KE +R+ L + +AG E ++L H Q T T ++N+
Sbjct: 531 LLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSES 590
Query: 187 KKSKFESITTNGDSFSPDL--------ALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQM 238
K E++ L +L++ + + + KE+V+ L + K ++
Sbjct: 591 HKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTEL 650
Query: 239 ILEKEKKITELKADFQ-YQESQMRAKMNQMEKTHKEVT--EQLQAKNRELLKQAAALSKS 295
+L E T +AD Q + ++ A ++ ++ +K T +Q+ AK ++ + + L
Sbjct: 651 LLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESH 710
Query: 296 KKSEK 300
K K
Sbjct: 711 LKEYK 715
Score = 33.5 bits (75), Expect = 0.24
Identities = 24/87 (27%), Positives = 45/87 (51%), Gaps = 10/87 (11%)
Query: 222 KEEVATLKKMLHQKDQMILEKEKKITEL-----KADFQYQESQM-----RAKMNQMEKTH 271
+++VA L+ L + ++ + EK TEL K Q+QE Q AK+ + +
Sbjct: 452 EQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDL 511
Query: 272 KEVTEQLQAKNRELLKQAAALSKSKKS 298
++V Q+ K++++ A L KSK++
Sbjct: 512 EQVLRQIGDKDQKIQNLEALLQKSKEN 538
Score = 30.8 bits (68), Expect = 1.6
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 8/80 (10%)
Query: 223 EEVATLKKMLHQ----KDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQL 278
E+VA LKK L Q D M LE+E++ +LK + + +SQ + E T ++ +L
Sbjct: 221 EDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASS----EATISQLRSEL 276
Query: 279 QAKNRELLKQAAALSKSKKS 298
+E+ L K K S
Sbjct: 277 AKGPQEVAVYVQELQKLKSS 296
Score = 30.8 bits (68), Expect = 1.6
Identities = 20/79 (25%), Positives = 40/79 (50%), Gaps = 9/79 (11%)
Query: 220 QLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKM-------NQMEKTHK 272
QL E LK+ + +++KE+++ +L+ E Q++ K+ +Q++KT +
Sbjct: 429 QLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQ 488
Query: 273 EVTEQ--LQAKNRELLKQA 289
+ EQ LQ L++A
Sbjct: 489 QHQEQQALQQSTTAKLREA 507
Score = 30.0 bits (66), Expect = 2.7
Identities = 32/164 (19%), Positives = 77/164 (46%), Gaps = 5/164 (3%)
Query: 138 KTKEQRKHLSSSSRAGHQEK--EQYSRLSGGGHYNSQKTLSTSSIQNEIPKKKSKFESIT 195
+ KEQR+ LSS +++ + +LS +K +++ +Q+++ K K + +
Sbjct: 436 RLKEQRQ-LSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQ 494
Query: 196 TNGDSFSPDLALDSPGTDHFVI-IAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQ 254
S + L + + I +++ L+ +L + + I EK+ +L A Q
Sbjct: 495 ALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQ 554
Query: 255 YQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKS 298
E + A +NQ+++ + + EQ+ +L Q+ + +++++
Sbjct: 555 AGEGE-TAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQEN 597
Score = 30.0 bits (66), Expect = 2.7
Identities = 19/81 (23%), Positives = 43/81 (53%), Gaps = 13/81 (16%)
Query: 220 QLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQ 279
QLK E+ ++++ L Q + + EK +E Q++ +N+++++ ++ +Q++
Sbjct: 928 QLKLELNSMQEQLIQAQNTLKQNEK-----------EEQQLQGNINELKQSSEQKKKQIE 976
Query: 280 AKNRELLKQAAALSKSKKSEK 300
A EL + A L K++ K
Sbjct: 977 ALQGEL--KIAVLQKTELENK 995
Score = 29.6 bits (65), Expect = 3.5
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 8/78 (10%)
Query: 218 IAQLKEEVATLKKMLHQKDQMILEKEK-------KITELKADFQYQESQMRAKMNQMEKT 270
I L E + T+KK + + E EK +I L+A Q + + RA + + K
Sbjct: 1243 ITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKG 1302
Query: 271 HKEVTEQLQAKNRELLKQ 288
E+ E+LQ K EL ++
Sbjct: 1303 EGEI-EKLQTKVLELQRK 1319
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 43.9 bits (102), Expect = 2e-04
Identities = 41/184 (22%), Positives = 84/184 (45%), Gaps = 20/184 (10%)
Query: 134 RVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSIQNEIPKKKSKFES 193
+VLQ+ K + +H A Q +E ++++S G + S +QNE+ + E
Sbjct: 1241 KVLQQVKAESEHKRKKLDA--QVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEE 1298
Query: 194 ITTNGDSFSPDLA-LDSPGTDHFVI--------------IAQLKEEVATLKKMLHQKDQM 238
G F+ D A L+S D + I QL+EE +L++ ++++
Sbjct: 1299 AEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEA 1358
Query: 239 ILEKEKKITELK---ADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKS 295
EK++ L+ AD + + + +E+ K++ + +A ++ L ++A A K
Sbjct: 1359 RKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKL 1418
Query: 296 KKSE 299
+K++
Sbjct: 1419 EKTK 1422
Score = 31.2 bits (69), Expect = 1.2
Identities = 19/84 (22%), Positives = 39/84 (46%), Gaps = 7/84 (8%)
Query: 221 LKEEVATLKKMLHQ-------KDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKE 273
L EE+ LK L + ++ ++E+++ ELK + + A++ M + H
Sbjct: 1144 LSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHAT 1203
Query: 274 VTEQLQAKNRELLKQAAALSKSKK 297
E+L + + + A L K+K+
Sbjct: 1204 ALEELSEQLEQAKRFKANLEKNKQ 1227
Score = 30.4 bits (67), Expect = 2.1
Identities = 18/80 (22%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
Query: 221 LKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQA 280
LK+ A ++ +D++I + K ++K D+Q + + RA +++ KE ++L++
Sbjct: 1626 LKDLEAQIEAANKARDEVIKQLRKLQAQMK-DYQRELEEARASRDEIFAQSKESEKKLKS 1684
Query: 281 KNRELLKQAAALSKSKKSEK 300
E+L+ L+ S+++ +
Sbjct: 1685 LEAEILQLQEELASSERARR 1704
Score = 29.3 bits (64), Expect = 4.6
Identities = 23/84 (27%), Positives = 43/84 (51%), Gaps = 7/84 (8%)
Query: 221 LKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQE----SQMRAKMNQMEKTHKEVTE 276
L E+A + + D + E++ ELKA Q E S+ +A ++ +E ++ E
Sbjct: 1769 LNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEE 1828
Query: 277 QLQAKNRELLKQAAALSKSKKSEK 300
QL+ + +E +AAA +++EK
Sbjct: 1829 QLEQEAKE---RAAANKLVRRTEK 1849
>gi|146229340 mutated in colorectal cancers isoform 1 [Homo sapiens]
Length = 1019
Score = 42.0 bits (97), Expect = 7e-04
Identities = 31/87 (35%), Positives = 46/87 (52%), Gaps = 8/87 (9%)
Query: 221 LKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQA 280
+KEE+A LK L+ +LEKEKK ELK +E+Q +A + +E EV EQ +
Sbjct: 815 MKEEMAELKAQLY-----LLEKEKKALELK--LSTREAQEQAYLVHIEHLKSEVEEQKEQ 867
Query: 281 KNRELLKQAAALSKSKKSEKSGAITSP 307
+ R L ++ SK K ++ SP
Sbjct: 868 RMRSLSSTSSG-SKDKPGKECADAASP 893
>gi|4505129 mutated in colorectal cancers isoform 2 [Homo sapiens]
Length = 829
Score = 42.0 bits (97), Expect = 7e-04
Identities = 31/87 (35%), Positives = 46/87 (52%), Gaps = 8/87 (9%)
Query: 221 LKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQA 280
+KEE+A LK L+ +LEKEKK ELK +E+Q +A + +E EV EQ +
Sbjct: 625 MKEEMAELKAQLY-----LLEKEKKALELK--LSTREAQEQAYLVHIEHLKSEVEEQKEQ 677
Query: 281 KNRELLKQAAALSKSKKSEKSGAITSP 307
+ R L ++ SK K ++ SP
Sbjct: 678 RMRSLSSTSSG-SKDKPGKECADAASP 703
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 42.0 bits (97), Expect = 7e-04
Identities = 48/176 (27%), Positives = 78/176 (44%), Gaps = 18/176 (10%)
Query: 130 LSYKRVLQKTKEQR-----KHLSSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSIQNEI 184
L +K + K ++Q K S ++ Q++E H SQ QNE
Sbjct: 152 LRFKEEVTKERDQLLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQRQNEA 211
Query: 185 PKKKSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEK 244
++ K E + D+ DS T+ I L++ V K+ L + +Q + KE+
Sbjct: 212 SREFRKKEKLEKELKQIQADM--DSRQTE----IKALQQYVQKSKEELQKLEQQL--KEQ 263
Query: 245 KITELKADFQYQESQMR-AKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSE 299
KI +A + ++ QMR AK+ Q + H V EQL +N +Q A K+K+ E
Sbjct: 264 KILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQEN----QQKALELKAKEEE 315
>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
Length = 237
Score = 40.8 bits (94), Expect = 0.002
Identities = 43/185 (23%), Positives = 83/185 (44%), Gaps = 16/185 (8%)
Query: 131 SYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSG---GGHYNSQKTLSTSSIQNEIPKK 187
++K+ L+K +E+ S SS Q K++ + SG +S + S+SS + KK
Sbjct: 58 NWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKK 117
Query: 188 KSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKM-----LHQKDQMILEK 242
+ K N S + ++ +D + + K+ +K L +K +M E
Sbjct: 118 QGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSED 177
Query: 243 EKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEKSG 302
+ +E ++ +Y E ++RAK + + ++ TE+ + K + SKK +K
Sbjct: 178 KPLSSESLSESEYIE-EVRAKKKKSSEEREKATEKTKKKKKHK-------KHSKKKKKKA 229
Query: 303 AITSP 307
A +SP
Sbjct: 230 ASSSP 234
>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
Length = 247
Score = 40.8 bits (94), Expect = 0.002
Identities = 43/185 (23%), Positives = 83/185 (44%), Gaps = 16/185 (8%)
Query: 131 SYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSG---GGHYNSQKTLSTSSIQNEIPKK 187
++K+ L+K +E+ S SS Q K++ + SG +S + S+SS + KK
Sbjct: 68 NWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKK 127
Query: 188 KSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKM-----LHQKDQMILEK 242
+ K N S + ++ +D + + K+ +K L +K +M E
Sbjct: 128 QGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSED 187
Query: 243 EKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEKSG 302
+ +E ++ +Y E ++RAK + + ++ TE+ + K + SKK +K
Sbjct: 188 KPLSSESLSESEYIE-EVRAKKKKSSEEREKATEKTKKKKKHK-------KHSKKKKKKA 239
Query: 303 AITSP 307
A +SP
Sbjct: 240 ASSSP 244
>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
[Homo sapiens]
Length = 1354
Score = 40.4 bits (93), Expect = 0.002
Identities = 34/146 (23%), Positives = 68/146 (46%), Gaps = 25/146 (17%)
Query: 178 SSIQNEIPKKKSKFESITTNGDSFSPD-----LALDSPGTDHFVIIAQLK------EEVA 226
S + ++ + + K E +T N + + L L+ ++ +LK + +
Sbjct: 742 SMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLK 801
Query: 227 TLKKMLHQKDQMILEKEK----KITELKADFQYQESQMRAKMNQME---------KTH-K 272
L+K + Q+ +LE ++ ++ +L ++ E QMR +Q+E KT K
Sbjct: 802 GLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVK 861
Query: 273 EVTEQLQAKNRELLKQAAALSKSKKS 298
E+ E+++ KNRE LK+ L K++
Sbjct: 862 ELKEEIEEKNRENLKKIQELQNEKET 887
Score = 32.0 bits (71), Expect = 0.71
Identities = 40/182 (21%), Positives = 71/182 (39%), Gaps = 21/182 (11%)
Query: 137 QKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSIQNEIPKKKSKFESIT- 195
+K + +K L ++ E + RL S+ S+ E+ ++ E+
Sbjct: 538 EKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKS 597
Query: 196 -TNGDSFSPDLALDSP----GTDHFVI------IAQLKEEVATLKKMLHQKD-------Q 237
T+ D + L++ G D +I I L+EEV LK L + +
Sbjct: 598 QTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQD 657
Query: 238 MILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNR--ELLKQAAALSKS 295
M+ EK+ L+ D Y+ ++ ++ Q HK +L K++ E K A
Sbjct: 658 MLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEME 717
Query: 296 KK 297
KK
Sbjct: 718 KK 719
Score = 28.9 bits (63), Expect = 6.0
Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 3/79 (3%)
Query: 222 KEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAK 281
+E +KM +++ LEKE++I+ LKA F E + + + ++ E + K
Sbjct: 957 RENEELTEKMKKAEEEYKLEKEEEISNLKAAF---EKNINTERTLKTQAVNKLAEIMNRK 1013
Query: 282 NRELLKQAAALSKSKKSEK 300
+ ++ ++ A +K EK
Sbjct: 1014 DFKIDRKKANTQDLRKKEK 1032
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 40.4 bits (93), Expect = 0.002
Identities = 48/261 (18%), Positives = 105/261 (40%), Gaps = 25/261 (9%)
Query: 44 EYQQESKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQ 103
E ++E + + KK Q + QY +++ + QR N Q
Sbjct: 191 ELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQ 250
Query: 104 CKQQCAFDRKDDRKKVDGKLLC--WLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYS 161
+ Q K++ + DG+ + + + + Q+ K Q L KEQ +
Sbjct: 251 LEPQAEVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCT 310
Query: 162 RLSGGGHYNSQKTLSTSSIQNEIPKKKSKFESITTNGDSFSPDLALDSPGTDHFVIIAQL 221
L T ++Q ++ ++ + E I D + +I QL
Sbjct: 311 LL----------TSEKEALQEQLDERLQELEKIK------------DLHMAEKTKLITQL 348
Query: 222 KEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAK 281
++ ++++ K +I E ++++ E + + +Q+R+++ QM +E+ EQ +
Sbjct: 349 RDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKS 408
Query: 282 NRELLKQ-AAALSKSKKSEKS 301
R ++ ALS ++K+E++
Sbjct: 409 ERAAFEELEKALSTAQKTEEA 429
Score = 32.3 bits (72), Expect = 0.54
Identities = 21/86 (24%), Positives = 45/86 (52%), Gaps = 7/86 (8%)
Query: 207 LDSPGTDHFVIIAQ----LKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMR- 261
+DS +H V I + LK+++ L+ +L ++D+ + E + + L+AD + E +++
Sbjct: 736 VDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQ 795
Query: 262 --AKMNQMEKTHKEVTEQLQAKNREL 285
AK++ + EQ +A +L
Sbjct: 796 ASAKLDVFQSYQSATHEQTKAYEEQL 821
Score = 31.6 bits (70), Expect = 0.92
Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 9/88 (10%)
Query: 218 IAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQ 277
+ QL EE TL Q + EKE +I +KAD + + + + E KE Q
Sbjct: 1278 LRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIE-------SLVTEKEALQKEGGNQ 1330
Query: 278 LQAKNRELLKQAAALSKSKKSEKSGAIT 305
QA + + + K + SE A+T
Sbjct: 1331 QQAASEK--ESCITQLKKELSENINAVT 1356
Score = 31.2 bits (69), Expect = 1.2
Identities = 38/173 (21%), Positives = 76/173 (43%), Gaps = 33/173 (19%)
Query: 138 KTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSIQNEIPKKKSKFESITTN 197
K+K ++K S + K Q +R+ + +QKT+ S+ NE+ K ++ + I
Sbjct: 1506 KSKMEKKE----SNLETELKSQTARIMELEDHITQKTIEIESL-NEVLKNYNQQKDI--- 1557
Query: 198 GDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQE 257
+H ++ +L+ +++ +KD + E E+KI L+ +
Sbjct: 1558 ---------------EHKELVQKLQH----FQELGEEKDNRVKEAEEKILTLENQVYSMK 1598
Query: 258 SQMRAKMNQMEKTH---KEVTEQLQAKNRELLKQAAAL---SKSKKSEKSGAI 304
+++ K ++E + K E+L+A L ++AA K K +K AI
Sbjct: 1599 AELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAI 1651
Score = 28.9 bits (63), Expect = 6.0
Identities = 27/127 (21%), Positives = 55/127 (43%), Gaps = 9/127 (7%)
Query: 171 SQKTLSTSSI-QNEIPKKKSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLK 229
++KTL + Q E+ S+ + +L++ TD ++K+E+
Sbjct: 672 NEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTD------KMKQELEA-- 723
Query: 230 KMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQA 289
KM QK+ + + I E + Q E ++ ++NQ+E KE + L+ +
Sbjct: 724 KMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLE 783
Query: 290 AALSKSK 296
A + +S+
Sbjct: 784 ADIKRSE 790
>gi|117414154 sodium channel associated protein 2 isoform b [Homo
sapiens]
Length = 939
Score = 40.4 bits (93), Expect = 0.002
Identities = 17/84 (20%), Positives = 48/84 (57%)
Query: 216 VIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVT 275
V + ++++ +TL + H K +++ E ++ E+K F+ +E +++A+ ++ + K
Sbjct: 798 VELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFENKEKKLKAERDKSIELQKNAM 857
Query: 276 EQLQAKNRELLKQAAALSKSKKSE 299
E+L + + +Q A+ ++ ++E
Sbjct: 858 EKLHSMDDAFKRQVDAIVEAHQAE 881
Score = 34.7 bits (78), Expect = 0.11
Identities = 32/114 (28%), Positives = 55/114 (48%), Gaps = 10/114 (8%)
Query: 178 SSIQNEIPKKKSKFESITTNGDSFSPDLALDSPGTD-HFVIIAQLKEEVATLKKMLHQKD 236
SS+ K +++ ES++ + DS II E + LK L +KD
Sbjct: 685 SSLAQNRGKLEAQIESLSRENECLRKTNESDSDALRIKCKIIDDQTETIRKLKDCLQEKD 744
Query: 237 QMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKN--RELLKQ 288
+ I ++KITE++ + + Q+ K +Q++ EV E+L+ N +E LKQ
Sbjct: 745 EHIKRLQEKITEIE---KCTQEQLDEKSSQLD----EVLEKLERHNERKEKLKQ 791
>gi|117414162 sodium channel associated protein 2 isoform a [Homo
sapiens]
Length = 1032
Score = 40.4 bits (93), Expect = 0.002
Identities = 17/84 (20%), Positives = 48/84 (57%)
Query: 216 VIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVT 275
V + ++++ +TL + H K +++ E ++ E+K F+ +E +++A+ ++ + K
Sbjct: 891 VELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFENKEKKLKAERDKSIELQKNAM 950
Query: 276 EQLQAKNRELLKQAAALSKSKKSE 299
E+L + + +Q A+ ++ ++E
Sbjct: 951 EKLHSMDDAFKRQVDAIVEAHQAE 974
Score = 34.7 bits (78), Expect = 0.11
Identities = 32/114 (28%), Positives = 55/114 (48%), Gaps = 10/114 (8%)
Query: 178 SSIQNEIPKKKSKFESITTNGDSFSPDLALDSPGTD-HFVIIAQLKEEVATLKKMLHQKD 236
SS+ K +++ ES++ + DS II E + LK L +KD
Sbjct: 778 SSLAQNRGKLEAQIESLSRENECLRKTNESDSDALRIKCKIIDDQTETIRKLKDCLQEKD 837
Query: 237 QMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKN--RELLKQ 288
+ I ++KITE++ + + Q+ K +Q++ EV E+L+ N +E LKQ
Sbjct: 838 EHIKRLQEKITEIE---KCTQEQLDEKSSQLD----EVLEKLERHNERKEKLKQ 884
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
domain 1 [Homo sapiens]
Length = 1412
Score = 40.0 bits (92), Expect = 0.003
Identities = 45/166 (27%), Positives = 68/166 (40%), Gaps = 8/166 (4%)
Query: 133 KRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSIQNEIPKKKSKFE 192
K + QK + + + + + K Q S L G Y+ + S +EI K++ E
Sbjct: 279 KEISQKCQVLDEDIDAKQKEIQSLKSQISALQKG--YSKVLCQTLSERNSEITSLKNEGE 336
Query: 193 SITTNGDSFS---PDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITEL 249
++ + S L D D V QLKEEV+ LK KD + + + L
Sbjct: 337 NLKRDNAITSGMVSSLQKDILAKDEQV--QQLKEEVSHLKSQNKDKDHQLEALGSRCSVL 394
Query: 250 KADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKS 295
K + + QE R EK K Q+Q +E+ K A L KS
Sbjct: 395 KEELK-QEDAHRELREAQEKELKLCKTQIQDMEKEMKKLRAELRKS 439
Score = 30.0 bits (66), Expect = 2.7
Identities = 33/140 (23%), Positives = 55/140 (39%), Gaps = 19/140 (13%)
Query: 172 QKTLSTSSIQNEIPKKKSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKM 231
+K+ + S+ + ++KSK E DS L L G VI L+ V L+
Sbjct: 437 RKSCTEQSVISRTLREKSKVEE-KLQEDSRRKLLQLQEMGNRESVIKINLERAVGQLEHF 495
Query: 232 LHQ-----------------KDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEV 274
Q DQ ++EK ++TE +FQ ++ ++ + +E
Sbjct: 496 RSQVIKATYGRAKPFRDKPVTDQQLIEKITQVTEDNINFQQKKWTLQKETQLSNSKQEET 555
Query: 275 TEQLQAKNRELLKQAAALSK 294
TE ++ K R L A K
Sbjct: 556 TENIE-KLRTSLDSCQACMK 574
>gi|14195601 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform b [Homo sapiens]
Length = 998
Score = 39.7 bits (91), Expect = 0.003
Identities = 41/164 (25%), Positives = 81/164 (49%), Gaps = 26/164 (15%)
Query: 158 EQYSRLSGGGHYNSQKTLSTS-----SIQNEIPKKKSKFESITTNGDSFSP---DLALDS 209
E+ SRL GG S T S S S + ++++ ++T+ + S +S
Sbjct: 832 ERLSRLESGG---SNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYES 888
Query: 210 PGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRA---KMNQ 266
T++ + +L+E L + + +++ +K++K ++ + + ++ + RA KM++
Sbjct: 889 ALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSE 948
Query: 267 MEK------------THKEVTEQLQAKNRELLKQAAALSKSKKS 298
ME+ T K++ EQLQA+NR L + A LS+S +S
Sbjct: 949 MEEEMKNLHQLKQIQTLKQMNEQLQAENRALTRVVARLSESIES 992
>gi|14195599 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform d [Homo sapiens]
Length = 224
Score = 39.7 bits (91), Expect = 0.003
Identities = 41/164 (25%), Positives = 81/164 (49%), Gaps = 26/164 (15%)
Query: 158 EQYSRLSGGGHYNSQKTLSTS-----SIQNEIPKKKSKFESITTNGDSFSP---DLALDS 209
E+ SRL GG S T S S S + ++++ ++T+ + S +S
Sbjct: 58 ERLSRLESGG---SNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYES 114
Query: 210 PGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRA---KMNQ 266
T++ + +L+E L + + +++ +K++K ++ + + ++ + RA KM++
Sbjct: 115 ALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSE 174
Query: 267 MEK------------THKEVTEQLQAKNRELLKQAAALSKSKKS 298
ME+ T K++ EQLQA+NR L + A LS+S +S
Sbjct: 175 MEEEMKNLHQLKQIQTLKQMNEQLQAENRALTRVVARLSESIES 218
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 39.7 bits (91), Expect = 0.003
Identities = 28/130 (21%), Positives = 63/130 (48%), Gaps = 5/130 (3%)
Query: 171 SQKTLSTSSIQNEIPKKKSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEE-VATLK 229
+Q T + +++ + K+ + E+ + +L+ S T + Q KEE A LK
Sbjct: 1190 TQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLK 1249
Query: 230 KMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQA 289
+ L + I + +K+++ ++ + + +R K+N++EK + +++L K R + +
Sbjct: 1250 EKLTDAKKQIKQVQKEVSVMRDE----DKLLRIKINELEKKKNQCSQELDMKQRTIQQLK 1305
Query: 290 AALSKSKKSE 299
L+ K E
Sbjct: 1306 EQLNNQKVEE 1315
Score = 30.8 bits (68), Expect = 1.6
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 23/172 (13%)
Query: 137 QKTKEQRKHLSSSS------RAGHQEKEQ-----YSRLSGGGHYNSQKTLSTSSIQNEIP 185
Q+T++ ++ LS+SS +A Q KE+ +L+ Q S +++E
Sbjct: 1215 QETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDK 1274
Query: 186 KKKSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKK 245
+ K + + S +L + I QLKE++ K ++ I + E+
Sbjct: 1275 LLRIKINELEKKKNQCSQELDMKQR------TIQQLKEQLNNQKV-----EEAIQQYERA 1323
Query: 246 ITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKK 297
+L + E MR + + E+T E + L+AK E+ + A L K K+
Sbjct: 1324 CKDLNVKEKIIED-MRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKE 1374
>gi|4758648 kinesin family member 5B [Homo sapiens]
Length = 963
Score = 39.3 bits (90), Expect = 0.004
Identities = 39/158 (24%), Positives = 67/158 (42%), Gaps = 23/158 (14%)
Query: 132 YKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSIQNEIPKKKSKF 191
+K+ +K KE+ K L ++ + E N + T I + K+K+
Sbjct: 340 WKKKYEKEKEKNKILRNTIQWLENE------------LNRWRNGETVPIDEQFDKEKANL 387
Query: 192 ESITTNGDSFSPDLALDSPGTDHFVI-------IAQLKEEVATLKKMLHQKDQMILEKEK 244
E+ T + D L D P T VI + +EE+A L K L KD+ I ++ +
Sbjct: 388 EAFTVDKDI---TLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQ 444
Query: 245 KITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKN 282
+ +LK QE + + + E+ +LQA+N
Sbjct: 445 LVEKLKTQMLDQEELLASTRRDQDNMQAEL-NRLQAEN 481
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 38.9 bits (89), Expect = 0.006
Identities = 37/162 (22%), Positives = 75/162 (46%), Gaps = 16/162 (9%)
Query: 140 KEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSI-------QNEIPKKKSKFE 192
+E + S+SS+ + ++ S+L +K ++ SSI + E+ +K K
Sbjct: 676 EELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIR 735
Query: 193 SITTNGDSFSPD--LALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELK 250
S+ TN ++ LA + H ++++++ L+ L +KDQ E+EK ++ L+
Sbjct: 736 SLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQ 795
Query: 251 ADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAAL 292
D + K + +E + +TE +E +K+ AL
Sbjct: 796 QD-------IICKQHHLESLDRLLTESKGEMKKENMKKDEAL 830
Score = 32.7 bits (73), Expect = 0.41
Identities = 24/92 (26%), Positives = 51/92 (55%), Gaps = 15/92 (16%)
Query: 218 IAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQES-----QMRAKMNQMEKTHK 272
I+QLK+E+ ++ + + + ++ E+E+ I QY+E+ ++R Q++ +H
Sbjct: 1213 ISQLKKEIERTQQRMKEMESVMKEQEQYIAT-----QYKEAIDLGQELRLTREQVQNSHT 1267
Query: 273 EVTE----QLQAKNRELLKQAAALSKSKKSEK 300
E+ E Q+QA+ RE+ + ++ L K+ K
Sbjct: 1268 ELAEARHQQVQAQ-REIERLSSELEDMKQLSK 1298
Score = 30.0 bits (66), Expect = 2.7
Identities = 33/181 (18%), Positives = 79/181 (43%), Gaps = 21/181 (11%)
Query: 134 RVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNS---QKTLSTSSIQNEIPKKKSK 190
+V + K+Q +H + EKE+ ++G + Q S ++ + + S+
Sbjct: 615 QVAESVKDQNQHTMNKQ----YEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQ 670
Query: 191 FESITTN-----GDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQK---DQMILEK 242
F+ I +S + + + + QL+E++ + + +Q ++EK
Sbjct: 671 FQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEK 730
Query: 243 EKKITELKADFQYQESQM-----RAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKK 297
+KI L+ + + ++ +AK +E+ HKE+ +Q++ +L K+ + +K
Sbjct: 731 NEKIRSLETNINTEHEKICLAFEKAKKIHLEQ-HKEMEKQIERLEAQLEKKDQQFKEQEK 789
Query: 298 S 298
+
Sbjct: 790 T 790
Score = 28.9 bits (63), Expect = 6.0
Identities = 18/84 (21%), Positives = 39/84 (46%)
Query: 217 IIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTE 276
++ + + ++ +KM+ +K+Q + E +++ +LK D Q Q + Q + E
Sbjct: 306 VLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALYNAEE 365
Query: 277 QLQAKNRELLKQAAALSKSKKSEK 300
+A + K A L K + E+
Sbjct: 366 LSKAFQQYKKKVAEKLEKVQAEEE 389
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 38.5 bits (88), Expect = 0.008
Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 11/82 (13%)
Query: 222 KEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAK 281
KEE+ + ++ + + I+E+EKK ELK K+ +K E+ EQ+ K
Sbjct: 321 KEEIQEKETIIEELNTKIIEEEKKTLELKD-----------KLTTADKLLGELQEQIVQK 369
Query: 282 NRELLKQAAALSKSKKSEKSGA 303
N+E+ L+ SK+ E+ +
Sbjct: 370 NQEIKNMKLELTNSKQKERQSS 391
Score = 35.4 bits (80), Expect = 0.064
Identities = 34/153 (22%), Positives = 77/153 (50%), Gaps = 20/153 (13%)
Query: 157 KEQYSRLSGGGHYNSQKTLSTSSIQNEIPKKKSKFESITTNGDSFSPDLALDSPGTDHFV 216
KE++ LS + ++ L ++S ++IP+ K +T + + FS D F+
Sbjct: 1511 KEEFKPLSKELGEHGKEILLSNSDPHDIPESKDCV--LTISEEMFSKDKT--------FI 1560
Query: 217 IIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQM------RAKMNQMEKT 270
+ + +E++ + M + M+ E++ + + QYQE Q +A M QME+
Sbjct: 1561 VRQSIHDEIS-VSSMDASRQLMLNEEQLEDMRQELVRQYQEHQQATELLRQAHMRQMERQ 1619
Query: 271 HKE---VTEQLQAKNRELLKQAAALSKSKKSEK 300
++ + E+++ NR+L ++++ +++ SE+
Sbjct: 1620 REDQEQLQEEIKRLNRQLAQRSSIDNENLVSER 1652
Score = 34.3 bits (77), Expect = 0.14
Identities = 45/195 (23%), Positives = 80/195 (41%), Gaps = 15/195 (7%)
Query: 105 KQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLS 164
++ DR + ++ + + L S++ L K KE + H+ + + +
Sbjct: 606 EKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLE-------IEHRINIEKLKDN 658
Query: 165 GGGHYNSQKTLSTSSIQNEIPKKKSKFESITTNGDSFSPDLALD-SPGTDHFVIIAQLKE 223
G HY Q +QNE+ +K + N + L L+ S D + K
Sbjct: 659 LGIHYKQQ----IDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKS 714
Query: 224 EVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNR 283
E TL+ QK+ IL +E+K K + + +++ K +EK KE LQ K
Sbjct: 715 EEMTLQINELQKEIEILRQEEKE---KGTLEQEVQELQLKTELLEKQMKEKENDLQEKFA 771
Query: 284 ELLKQAAALSKSKKS 298
+L + + L KK+
Sbjct: 772 QLEAENSILKDEKKT 786
Score = 31.6 bits (70), Expect = 0.92
Identities = 41/187 (21%), Positives = 73/187 (39%), Gaps = 28/187 (14%)
Query: 137 QKTKEQRKHLSSSSRAGHQEKEQYSRLSGGG-----------------HYNSQKTLSTSS 179
Q +E K + S S A Q+ E SR+SGG HY ++ LS
Sbjct: 1439 QLEEEVAKVIVSMSIAFAQQTE-LSRISGGKENTASSKQAHAVCQQEQHYFNEMKLSQDQ 1497
Query: 180 I-----QNEIPKKKSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQ 234
I + K K +F+ ++ ++ L + I + K+ V T+ + +
Sbjct: 1498 IGFQTFETVDVKFKEEFKPLSKELGEHGKEILLSNSDPHD---IPESKDCVLTISEEMFS 1554
Query: 235 KDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNR--ELLKQAAAL 292
KD+ + ++ E+ Q+ Q+E +E+ Q Q + ELL+QA
Sbjct: 1555 KDKTFIVRQSIHDEISVSSMDASRQLMLNEEQLEDMRQELVRQYQEHQQATELLRQAHMR 1614
Query: 293 SKSKKSE 299
++ E
Sbjct: 1615 QMERQRE 1621
Score = 31.2 bits (69), Expect = 1.2
Identities = 15/65 (23%), Positives = 37/65 (56%), Gaps = 1/65 (1%)
Query: 220 QLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQ 279
+LK+++ T K+L + + I++K ++I +K + + + R ++++ V E+LQ
Sbjct: 347 ELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTV-EELQ 405
Query: 280 AKNRE 284
+N +
Sbjct: 406 KRNHK 410
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 38.5 bits (88), Expect = 0.008
Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 11/82 (13%)
Query: 222 KEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAK 281
KEE+ + ++ + + I+E+EKK ELK K+ +K E+ EQ+ K
Sbjct: 321 KEEIQEKETIIEELNTKIIEEEKKTLELKD-----------KLTTADKLLGELQEQIVQK 369
Query: 282 NRELLKQAAALSKSKKSEKSGA 303
N+E+ L+ SK+ E+ +
Sbjct: 370 NQEIKNMKLELTNSKQKERQSS 391
Score = 35.4 bits (80), Expect = 0.064
Identities = 34/153 (22%), Positives = 77/153 (50%), Gaps = 20/153 (13%)
Query: 157 KEQYSRLSGGGHYNSQKTLSTSSIQNEIPKKKSKFESITTNGDSFSPDLALDSPGTDHFV 216
KE++ LS + ++ L ++S ++IP+ K +T + + FS D F+
Sbjct: 1511 KEEFKPLSKELGEHGKEILLSNSDPHDIPESKDCV--LTISEEMFSKDKT--------FI 1560
Query: 217 IIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQM------RAKMNQMEKT 270
+ + +E++ + M + M+ E++ + + QYQE Q +A M QME+
Sbjct: 1561 VRQSIHDEIS-VSSMDASRQLMLNEEQLEDMRQELVRQYQEHQQATELLRQAHMRQMERQ 1619
Query: 271 HKE---VTEQLQAKNRELLKQAAALSKSKKSEK 300
++ + E+++ NR+L ++++ +++ SE+
Sbjct: 1620 REDQEQLQEEIKRLNRQLAQRSSIDNENLVSER 1652
Score = 34.3 bits (77), Expect = 0.14
Identities = 45/195 (23%), Positives = 80/195 (41%), Gaps = 15/195 (7%)
Query: 105 KQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLS 164
++ DR + ++ + + L S++ L K KE + H+ + + +
Sbjct: 606 EKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLE-------IEHRINIEKLKDN 658
Query: 165 GGGHYNSQKTLSTSSIQNEIPKKKSKFESITTNGDSFSPDLALD-SPGTDHFVIIAQLKE 223
G HY Q +QNE+ +K + N + L L+ S D + K
Sbjct: 659 LGIHYKQQ----IDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKS 714
Query: 224 EVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNR 283
E TL+ QK+ IL +E+K K + + +++ K +EK KE LQ K
Sbjct: 715 EEMTLQINELQKEIEILRQEEKE---KGTLEQEVQELQLKTELLEKQMKEKENDLQEKFA 771
Query: 284 ELLKQAAALSKSKKS 298
+L + + L KK+
Sbjct: 772 QLEAENSILKDEKKT 786
Score = 31.6 bits (70), Expect = 0.92
Identities = 41/187 (21%), Positives = 73/187 (39%), Gaps = 28/187 (14%)
Query: 137 QKTKEQRKHLSSSSRAGHQEKEQYSRLSGGG-----------------HYNSQKTLSTSS 179
Q +E K + S S A Q+ E SR+SGG HY ++ LS
Sbjct: 1439 QLEEEVAKVIVSMSIAFAQQTE-LSRISGGKENTASSKQAHAVCQQEQHYFNEMKLSQDQ 1497
Query: 180 I-----QNEIPKKKSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQ 234
I + K K +F+ ++ ++ L + I + K+ V T+ + +
Sbjct: 1498 IGFQTFETVDVKFKEEFKPLSKELGEHGKEILLSNSDPHD---IPESKDCVLTISEEMFS 1554
Query: 235 KDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNR--ELLKQAAAL 292
KD+ + ++ E+ Q+ Q+E +E+ Q Q + ELL+QA
Sbjct: 1555 KDKTFIVRQSIHDEISVSSMDASRQLMLNEEQLEDMRQELVRQYQEHQQATELLRQAHMR 1614
Query: 293 SKSKKSE 299
++ E
Sbjct: 1615 QMERQRE 1621
Score = 31.2 bits (69), Expect = 1.2
Identities = 15/65 (23%), Positives = 37/65 (56%), Gaps = 1/65 (1%)
Query: 220 QLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQ 279
+LK+++ T K+L + + I++K ++I +K + + + R ++++ V E+LQ
Sbjct: 347 ELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTV-EELQ 405
Query: 280 AKNRE 284
+N +
Sbjct: 406 KRNHK 410
>gi|35038601 spindle assembly abnormal protein 6 [Homo sapiens]
Length = 657
Score = 38.5 bits (88), Expect = 0.008
Identities = 52/233 (22%), Positives = 97/233 (41%), Gaps = 27/233 (11%)
Query: 85 CQRCTNSEKKYGPPYSCEQCKQQCAFDRK---DDRKKVDGKLLCWL---CTLSYKRVLQK 138
C +C+ E+K S + +Q F RK + ++++D W L+ K +
Sbjct: 156 CLKCSK-EEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQEL 214
Query: 139 TKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSIQNEIPKKKSKFESITTN- 197
T E+ K L + + Q ++Q L N + +QN + + ++ + +T
Sbjct: 215 TNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQ------LQNRLSELEAANKDLTERK 268
Query: 198 --GDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQY 255
GDS +L G + + + K+EV +L++ D EKEK + +L+
Sbjct: 269 YKGDSTIRELKAKLSGVEEE--LQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAV 326
Query: 256 QESQMRAKMNQMEKT---------HKEVTEQLQAKNRELLKQAAALSKSKKSE 299
E +++ K + +T K V E+ KN+ L + A KS +E
Sbjct: 327 LEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAE 379
Score = 30.4 bits (67), Expect = 2.1
Identities = 20/85 (23%), Positives = 44/85 (51%), Gaps = 6/85 (7%)
Query: 229 KKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQ-AKNRELL- 286
+K+L +K++ + +++K++ ++ + +E ++ Q+E T K++ E Q KN E L
Sbjct: 412 EKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLI 471
Query: 287 ----KQAAALSKSKKSEKSGAITSP 307
K+ +K + G T+P
Sbjct: 472 TWLNKELNENQLVRKQDVLGPSTTP 496
>gi|157785668 coiled-coil domain containing 39 [Homo sapiens]
Length = 941
Score = 38.5 bits (88), Expect = 0.008
Identities = 39/189 (20%), Positives = 83/189 (43%), Gaps = 29/189 (15%)
Query: 128 CTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSIQNEIPKK 187
C L R+ Q+T+E+ + +EK ++ G + +K +S + ++ K
Sbjct: 244 CALELARIKQETREKENLV--------KEKIKFLESEIGNNTEFEKRISVAD--RKLLKC 293
Query: 188 KSKFESITTN-----GDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQK------- 235
++ ++ T+ G+ S ++ +D + L++ ++ +KK +H++
Sbjct: 294 RTAYQDHETSRIQLKGELDSLKATVNRTSSD----LEALRKNISKIKKDIHEETARLQKT 349
Query: 236 ---DQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAAL 292
+++I K K+ITE + + + + + + EK KEV QL L K+A L
Sbjct: 350 KNHNEIIQTKLKEITEKTMSVEEKATNLEDMLKEEEKDVKEVDVQLNLIKGVLFKKAQEL 409
Query: 293 SKSKKSEKS 301
EK+
Sbjct: 410 QTETMKEKA 418
Score = 30.4 bits (67), Expect = 2.1
Identities = 25/127 (19%), Positives = 52/127 (40%), Gaps = 9/127 (7%)
Query: 170 NSQKTLSTSSIQNEIPKKKSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLK 229
NS + S + NE+ + E F DL ++ LK EV +
Sbjct: 522 NSDEKQSLMTKINELNLFIDRSEKELDKAKGFKQDLMIEDN---------LLKLEVKRTR 572
Query: 230 KMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQA 289
+MLH K + +L EK+ +L + + +++ + + V ++ + + E ++
Sbjct: 573 EMLHSKAEEVLSLEKRKQQLYTAMEERTEEIKVHKTMLASQIRYVDQERENISTEFRERL 632
Query: 290 AALSKSK 296
+ + K K
Sbjct: 633 SKIEKLK 639
>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 38.1 bits (87), Expect = 0.010
Identities = 24/83 (28%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
Query: 218 IAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQ 277
IA LKEE+ +K +K++ +++ K ITE+ A+F E +R + KT ++Q
Sbjct: 441 IAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANF---EKSVRLNEKMITKTVARYSQQ 497
Query: 278 LQAKNRELLKQAAALSKSKKSEK 300
L E + + L K K +++
Sbjct: 498 LNDLKAENARLNSELEKEKHNKE 520
>gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1002
Score = 38.1 bits (87), Expect = 0.010
Identities = 24/83 (28%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
Query: 218 IAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQ 277
IA LKEE+ +K +K++ +++ K ITE+ A+F E +R + KT ++Q
Sbjct: 334 IAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANF---EKSVRLNEKMITKTVARYSQQ 390
Query: 278 LQAKNRELLKQAAALSKSKKSEK 300
L E + + L K K +++
Sbjct: 391 LNDLKAENARLNSELEKEKHNKE 413
>gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 38.1 bits (87), Expect = 0.010
Identities = 24/83 (28%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
Query: 218 IAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQ 277
IA LKEE+ +K +K++ +++ K ITE+ A+F E +R + KT ++Q
Sbjct: 441 IAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANF---EKSVRLNEKMITKTVARYSQQ 497
Query: 278 LQAKNRELLKQAAALSKSKKSEK 300
L E + + L K K +++
Sbjct: 498 LNDLKAENARLNSELEKEKHNKE 520
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.127 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,121,755
Number of Sequences: 37866
Number of extensions: 567162
Number of successful extensions: 4843
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 163
Number of HSP's successfully gapped in prelim test: 409
Number of HSP's that attempted gapping in prelim test: 3620
Number of HSP's gapped (non-prelim): 1543
length of query: 307
length of database: 18,247,518
effective HSP length: 102
effective length of query: 205
effective length of database: 14,385,186
effective search space: 2948963130
effective search space used: 2948963130
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.