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Search of human proteins with 227430338
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|227430338 SH3 domain containing, Ysc84-like 1 isoform 2
[Homo sapiens]
(323 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|227430338 SH3 domain containing, Ysc84-like 1 isoform 2 [Homo... 640 0.0
gi|227430336 SH3 domain containing, Ysc84-like 1 isoform 1 [Homo... 629 e-180
gi|4506929 SH3-domain GRB2-like 1 [Homo sapiens] 62 5e-10
gi|4504111 growth factor receptor-bound protein 2 isoform 1 [Hom... 61 1e-09
gi|45359859 growth factor receptor-bound protein 2 isoform 2 [Ho... 61 1e-09
gi|223468657 SH3-domain GRB2-like 3 [Homo sapiens] 61 2e-09
gi|189083742 neutrophil cytosolic factor 2 [Homo sapiens] 59 6e-09
gi|67189970 neutrophil cytosolic factor 2 [Homo sapiens] 59 6e-09
gi|4506931 SH3-domain GRB2-like 2 [Homo sapiens] 57 3e-08
gi|55956916 myosin IE [Homo sapiens] 56 4e-08
gi|39752673 SH3 and cysteine rich domain 2 [Homo sapiens] 55 6e-08
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 55 8e-08
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 55 8e-08
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 55 8e-08
gi|21450838 SH3 and cysteine rich domain 3 [Homo sapiens] 55 1e-07
gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H... 54 1e-07
gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [H... 54 1e-07
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 54 2e-07
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 54 2e-07
gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens] 54 2e-07
gi|193083143 SH3 domain containing 19 isoform b [Homo sapiens] 54 2e-07
gi|193083141 SH3 domain containing 19 isoform a [Homo sapiens] 54 2e-07
gi|150010572 SH3 domain containing ring finger 3 [Homo sapiens] 54 2e-07
gi|4507249 signal transducing adaptor molecule 1 [Homo sapiens] 54 2e-07
gi|188219625 signal transducing adaptor molecule 2 [Homo sapiens] 54 2e-07
gi|51988887 SH3 domain containing ring finger 1 [Homo sapiens] 54 2e-07
gi|148747351 protein kinase C and casein kinase substrate in neu... 53 3e-07
gi|4507247 SH3 and cysteine rich domain [Homo sapiens] 53 3e-07
gi|115527076 src kinase associated phosphoprotein 1 isoform 2 [H... 53 4e-07
gi|24308229 protein kinase C and casein kinase substrate in neur... 52 5e-07
>gi|227430338 SH3 domain containing, Ysc84-like 1 isoform 2 [Homo
sapiens]
Length = 323
Score = 640 bits (1651), Expect = 0.0
Identities = 323/323 (100%), Positives = 323/323 (100%)
Query: 1 MNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAILSVIKAGFLVT 60
MNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAILSVIKAGFLVT
Sbjct: 1 MNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAILSVIKAGFLVT 60
Query: 61 ARGGSGIVVARLPDGKWSAPSAIGIAGLGGGFEIGIEVSDLVIILNYDRAVEAFAKGGNL 120
ARGGSGIVVARLPDGKWSAPSAIGIAGLGGGFEIGIEVSDLVIILNYDRAVEAFAKGGNL
Sbjct: 61 ARGGSGIVVARLPDGKWSAPSAIGIAGLGGGFEIGIEVSDLVIILNYDRAVEAFAKGGNL 120
Query: 121 TLGGNLTVAVGPLGRNLEGNVALRSSAAVFTYCKSRGLFAGVSLEGSCLIERKETNRKFY 180
TLGGNLTVAVGPLGRNLEGNVALRSSAAVFTYCKSRGLFAGVSLEGSCLIERKETNRKFY
Sbjct: 121 TLGGNLTVAVGPLGRNLEGNVALRSSAAVFTYCKSRGLFAGVSLEGSCLIERKETNRKFY 180
Query: 181 CQDIRAYDILFGDTPRPAQAEDLYEILDSFTEKYENEGQRINARKAAREQRKSSAKELPP 240
CQDIRAYDILFGDTPRPAQAEDLYEILDSFTEKYENEGQRINARKAAREQRKSSAKELPP
Sbjct: 181 CQDIRAYDILFGDTPRPAQAEDLYEILDSFTEKYENEGQRINARKAAREQRKSSAKELPP 240
Query: 241 KPLSRPQQSSAPVQLNSGSQSNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSH 300
KPLSRPQQSSAPVQLNSGSQSNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSH
Sbjct: 241 KPLSRPQQSSAPVQLNSGSQSNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSH 300
Query: 301 FDWWEGKLRGQTGIFPANYVTMN 323
FDWWEGKLRGQTGIFPANYVTMN
Sbjct: 301 FDWWEGKLRGQTGIFPANYVTMN 323
>gi|227430336 SH3 domain containing, Ysc84-like 1 isoform 1 [Homo
sapiens]
Length = 342
Score = 629 bits (1621), Expect = e-180
Identities = 323/342 (94%), Positives = 323/342 (94%), Gaps = 19/342 (5%)
Query: 1 MNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAILSVIKAGFLVT 60
MNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAILSVIKAGFLVT
Sbjct: 1 MNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAILSVIKAGFLVT 60
Query: 61 ARGGSGIVVARLPDGKWSAPSAIGIAGLGGGFEIGIEVSDLVIILNYDRAVEAFAKGGNL 120
ARGGSGIVVARLPDGKWSAPSAIGIAGLGGGFEIGIEVSDLVIILNYDRAVEAFAKGGNL
Sbjct: 61 ARGGSGIVVARLPDGKWSAPSAIGIAGLGGGFEIGIEVSDLVIILNYDRAVEAFAKGGNL 120
Query: 121 TLGGNLTVAVGPLGRNLEGNVALRSSAAVFTYCKSRGLFAGVSLEGSCLIERKETNRKFY 180
TLGGNLTVAVGPLGRNLEGNVALRSSAAVFTYCKSRGLFAGVSLEGSCLIERKETNRKFY
Sbjct: 121 TLGGNLTVAVGPLGRNLEGNVALRSSAAVFTYCKSRGLFAGVSLEGSCLIERKETNRKFY 180
Query: 181 CQDIRAYDILFGDTPRPAQAEDLYEILDSFTEKYENEGQRINARKAAREQRKSSAKELPP 240
CQDIRAYDILFGDTPRPAQAEDLYEILDSFTEKYENEGQRINARKAAREQRKSSAKELPP
Sbjct: 181 CQDIRAYDILFGDTPRPAQAEDLYEILDSFTEKYENEGQRINARKAAREQRKSSAKELPP 240
Query: 241 KPLSRPQQSSAPVQLNSGSQS-------------------NLNQPIEVTALYSFEGQQPG 281
KPLSRPQQSSAPVQLNSGSQS NLNQPIEVTALYSFEGQQPG
Sbjct: 241 KPLSRPQQSSAPVQLNSGSQSNRNEYKLYPGLSSYHERVGNLNQPIEVTALYSFEGQQPG 300
Query: 282 DLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTMN 323
DLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTMN
Sbjct: 301 DLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTMN 342
>gi|4506929 SH3-domain GRB2-like 1 [Homo sapiens]
Length = 368
Score = 62.4 bits (150), Expect = 5e-10
Identities = 44/137 (32%), Positives = 64/137 (46%), Gaps = 28/137 (20%)
Query: 205 EILDSFTEKYENEGQRINARKAAREQRKSSAKELPPKPLSRPQQSSA------------- 251
+ILD EK + R ++R +R+ K P L P+QS+
Sbjct: 231 QILDELAEKLK----RRMREASSRPKREYKPKPREPFDLGEPEQSNGGFPCTTAPKIAAS 286
Query: 252 --------PVQLNSGSQSNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDW 303
P++ S S L+QP ALY FE + G+L F GD IT+ ++ D +W
Sbjct: 287 SSFRSSDKPIRTPSRSMPPLDQP-SCKALYDFEPENDGELGFHEGDVITLTNQIDE--NW 343
Query: 304 WEGKLRGQTGIFPANYV 320
+EG L GQ+G FP +YV
Sbjct: 344 YEGMLDGQSGFFPLSYV 360
>gi|4504111 growth factor receptor-bound protein 2 isoform 1 [Homo
sapiens]
Length = 217
Score = 61.2 bits (147), Expect = 1e-09
Identities = 28/57 (49%), Positives = 38/57 (66%), Gaps = 2/57 (3%)
Query: 265 QPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVT 321
QP V AL+ F+ Q+ G+L F+ GD I V+ +D + WW+G GQTG+FP NYVT
Sbjct: 157 QPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPN--WWKGACHGQTGMFPRNYVT 211
Score = 39.7 bits (91), Expect = 0.004
Identities = 17/56 (30%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Query: 267 IEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTM 322
+E A Y F+ +L+F+ GD + V+++ + +W++ +L G+ G P NY+ M
Sbjct: 1 MEAIAKYDFKATADDELSFKRGDILKVLNE-ECDQNWYKAELNGKDGFIPKNYIEM 55
>gi|45359859 growth factor receptor-bound protein 2 isoform 2 [Homo
sapiens]
Length = 176
Score = 61.2 bits (147), Expect = 1e-09
Identities = 28/57 (49%), Positives = 38/57 (66%), Gaps = 2/57 (3%)
Query: 265 QPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVT 321
QP V AL+ F+ Q+ G+L F+ GD I V+ +D + WW+G GQTG+FP NYVT
Sbjct: 116 QPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPN--WWKGACHGQTGMFPRNYVT 170
Score = 39.7 bits (91), Expect = 0.004
Identities = 17/56 (30%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Query: 267 IEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTM 322
+E A Y F+ +L+F+ GD + V+++ + +W++ +L G+ G P NY+ M
Sbjct: 1 MEAIAKYDFKATADDELSFKRGDILKVLNE-ECDQNWYKAELNGKDGFIPKNYIEM 55
>gi|223468657 SH3-domain GRB2-like 3 [Homo sapiens]
Length = 347
Score = 60.8 bits (146), Expect = 2e-09
Identities = 37/132 (28%), Positives = 66/132 (50%), Gaps = 13/132 (9%)
Query: 199 QAEDLYEILDSFTEKYENEGQRINARKAAREQRKSSAKELP-----PKPLSRPQQ----- 248
Q L +++ + + + + ++ + R S+A +P P+P+ R
Sbjct: 211 QVSQLAVFIEAALDYHRQSTEILQELQSKLQMRISAASSVPRREYKPRPVKRSSSELNGV 270
Query: 249 SSAPVQLNSGSQSNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKL 308
S+ V +GS ++QP LY FE + G+L F+ GD IT+ ++ D + W+EG +
Sbjct: 271 STTSVVKTTGSNIPMDQPC-CRGLYDFEPENQGELGFKEGDIITLTNQIDEN--WYEGMI 327
Query: 309 RGQTGIFPANYV 320
G++G FP NYV
Sbjct: 328 HGESGFFPINYV 339
>gi|189083742 neutrophil cytosolic factor 2 [Homo sapiens]
Length = 526
Score = 58.9 bits (141), Expect = 6e-09
Identities = 30/75 (40%), Positives = 45/75 (60%), Gaps = 2/75 (2%)
Query: 246 PQQSSAPVQLNSGSQSNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWE 305
P++S N ++ L + +V AL+S+E QP DL FQ GD I V+SK + +W E
Sbjct: 439 PKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNE--EWLE 496
Query: 306 GKLRGQTGIFPANYV 320
G+ +G+ GIFP +V
Sbjct: 497 GECKGKVGIFPKVFV 511
>gi|67189970 neutrophil cytosolic factor 2 [Homo sapiens]
Length = 526
Score = 58.9 bits (141), Expect = 6e-09
Identities = 30/75 (40%), Positives = 45/75 (60%), Gaps = 2/75 (2%)
Query: 246 PQQSSAPVQLNSGSQSNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWE 305
P++S N ++ L + +V AL+S+E QP DL FQ GD I V+SK + +W E
Sbjct: 439 PKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNE--EWLE 496
Query: 306 GKLRGQTGIFPANYV 320
G+ +G+ GIFP +V
Sbjct: 497 GECKGKVGIFPKVFV 511
>gi|4506931 SH3-domain GRB2-like 2 [Homo sapiens]
Length = 352
Score = 56.6 bits (135), Expect = 3e-08
Identities = 40/114 (35%), Positives = 58/114 (50%), Gaps = 15/114 (13%)
Query: 219 QRINARKAAREQRKSSA--KELPPKP-LSRPQQSSAPVQLNSG---------SQSNLNQP 266
Q++ R R ++ SS +E PKP +S + Q N G S ++QP
Sbjct: 234 QQVTVRLEERIRQASSQPRREYQPKPRMSLEFPTGDSTQPNGGLSHTGTPKPSGVQMDQP 293
Query: 267 IEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 320
ALY FE + G+L F+ GD IT+ ++ D +W+EG L G +G FP NYV
Sbjct: 294 C-CRALYDFEPENEGELGFKEGDIITLTNQIDE--NWYEGMLHGHSGFFPINYV 344
>gi|55956916 myosin IE [Homo sapiens]
Length = 1108
Score = 56.2 bits (134), Expect = 4e-08
Identities = 32/96 (33%), Positives = 50/96 (52%), Gaps = 14/96 (14%)
Query: 226 AAREQRKSSAKELPPKPLSRPQQSSAPVQLNSGSQSNLNQPIEVTALYSFEGQQPGDLNF 285
AA +R+++++ P +PQ P Q + ALY+++ Q +L+F
Sbjct: 1025 AAGVRRQTTSRPPPAGGRPKPQPKPKP------------QVPQCKALYAYDAQDTDELSF 1072
Query: 286 QAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVT 321
A D I +I + S WW G+LRG+ G+FP NYVT
Sbjct: 1073 NANDIIDIIKEDPS--GWWTGRLRGKQGLFPNNYVT 1106
>gi|39752673 SH3 and cysteine rich domain 2 [Homo sapiens]
Length = 411
Score = 55.5 bits (132), Expect = 6e-08
Identities = 29/76 (38%), Positives = 43/76 (56%), Gaps = 3/76 (3%)
Query: 246 PQQSSAPVQLNSGS-QSNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWW 304
P++ S QL + + ++ ALY F Q+ DL Q GDRI ++ DS+ DWW
Sbjct: 273 PEEKSPGQQLPKATLRKDVGPMYSYVALYKFLPQENNDLALQPGDRIMLVD--DSNEDWW 330
Query: 305 EGKLRGQTGIFPANYV 320
+GK+ + G FPAN+V
Sbjct: 331 KGKIGDRVGFFPANFV 346
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 55.1 bits (131), Expect = 8e-08
Identities = 23/55 (41%), Positives = 35/55 (63%), Gaps = 2/55 (3%)
Query: 268 EVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTM 322
+V A+Y + +L+F G I V++K D DWW+G++ G TG+FP+NYV M
Sbjct: 1104 QVIAMYDYAANNEDELSFSKGQLINVMNKDDP--DWWQGEINGVTGLFPSNYVKM 1156
Score = 52.4 bits (124), Expect = 5e-07
Identities = 30/90 (33%), Positives = 44/90 (48%), Gaps = 4/90 (4%)
Query: 232 KSSAKELPPKPLSRPQQSSAPVQLNSGSQSNL-NQPIEVTALYSFEGQQPGDLNFQAGDR 290
KS K +P + R + + +N S + E ALY + +PGDL F G+
Sbjct: 921 KSYVKIIPGSEVKREEPEALYAAVNKKPTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEE 980
Query: 291 ITVISKTDSHFDWWEGKLRGQTGIFPANYV 320
I V K +WW G + ++GIFP+NYV
Sbjct: 981 ILVTQKDG---EWWTGSIGDRSGIFPSNYV 1007
Score = 47.0 bits (110), Expect = 2e-05
Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 9/109 (8%)
Query: 212 EKYENEGQRINARKAAREQRKSSAKELPPKPLSRPQQSSAPVQLNSGSQSNLNQPIEVTA 271
EK + + K E+RK+ K+ K + ++ + + + A
Sbjct: 687 EKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLKAEEKK---------RETASVLVNYRA 737
Query: 272 LYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 320
LY FE + +++F +GD I V KT W G +G G FP NYV
Sbjct: 738 LYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYV 786
Score = 40.0 bits (92), Expect = 0.003
Identities = 20/61 (32%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Query: 260 QSNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANY 319
Q + + ++ AL S+ ++ LNF D ITV+ + ++ WW G++ G G FP +Y
Sbjct: 867 QGQVVENLKAQALCSWTAKKDNHLNFSKHDIITVLEQQEN---WWFGEVHGGRGWFPKSY 923
Query: 320 V 320
V
Sbjct: 924 V 924
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 55.1 bits (131), Expect = 8e-08
Identities = 23/55 (41%), Positives = 35/55 (63%), Gaps = 2/55 (3%)
Query: 268 EVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTM 322
+V A+Y + +L+F G I V++K D DWW+G++ G TG+FP+NYV M
Sbjct: 1131 QVIAMYDYAANNEDELSFSKGQLINVMNKDDP--DWWQGEINGVTGLFPSNYVKM 1183
Score = 52.4 bits (124), Expect = 5e-07
Identities = 30/90 (33%), Positives = 44/90 (48%), Gaps = 4/90 (4%)
Query: 232 KSSAKELPPKPLSRPQQSSAPVQLNSGSQSNL-NQPIEVTALYSFEGQQPGDLNFQAGDR 290
KS K +P + R + + +N S + E ALY + +PGDL F G+
Sbjct: 948 KSYVKIIPGSEVKREEPEALYAAVNKKPTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEE 1007
Query: 291 ITVISKTDSHFDWWEGKLRGQTGIFPANYV 320
I V K +WW G + ++GIFP+NYV
Sbjct: 1008 ILVTQKDG---EWWTGSIGDRSGIFPSNYV 1034
Score = 47.0 bits (110), Expect = 2e-05
Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 9/109 (8%)
Query: 212 EKYENEGQRINARKAAREQRKSSAKELPPKPLSRPQQSSAPVQLNSGSQSNLNQPIEVTA 271
EK + + K E+RK+ K+ K + ++ + + + A
Sbjct: 714 EKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLKAEEKK---------RETASVLVNYRA 764
Query: 272 LYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 320
LY FE + +++F +GD I V KT W G +G G FP NYV
Sbjct: 765 LYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYV 813
Score = 40.0 bits (92), Expect = 0.003
Identities = 20/61 (32%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Query: 260 QSNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANY 319
Q + + ++ AL S+ ++ LNF D ITV+ + ++ WW G++ G G FP +Y
Sbjct: 894 QGQVVENLKAQALCSWTAKKDNHLNFSKHDIITVLEQQEN---WWFGEVHGGRGWFPKSY 950
Query: 320 V 320
V
Sbjct: 951 V 951
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 55.1 bits (131), Expect = 8e-08
Identities = 23/55 (41%), Positives = 35/55 (63%), Gaps = 2/55 (3%)
Query: 268 EVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTM 322
+V A+Y + +L+F G I V++K D DWW+G++ G TG+FP+NYV M
Sbjct: 1131 QVIAMYDYAANNEDELSFSKGQLINVMNKDDP--DWWQGEINGVTGLFPSNYVKM 1183
Score = 52.4 bits (124), Expect = 5e-07
Identities = 30/90 (33%), Positives = 44/90 (48%), Gaps = 4/90 (4%)
Query: 232 KSSAKELPPKPLSRPQQSSAPVQLNSGSQSNL-NQPIEVTALYSFEGQQPGDLNFQAGDR 290
KS K +P + R + + +N S + E ALY + +PGDL F G+
Sbjct: 948 KSYVKIIPGSEVKREEPEALYAAVNKKPTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEE 1007
Query: 291 ITVISKTDSHFDWWEGKLRGQTGIFPANYV 320
I V K +WW G + ++GIFP+NYV
Sbjct: 1008 ILVTQKDG---EWWTGSIGDRSGIFPSNYV 1034
Score = 47.0 bits (110), Expect = 2e-05
Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 9/109 (8%)
Query: 212 EKYENEGQRINARKAAREQRKSSAKELPPKPLSRPQQSSAPVQLNSGSQSNLNQPIEVTA 271
EK + + K E+RK+ K+ K + ++ + + + A
Sbjct: 714 EKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLKAEEKK---------RETASVLVNYRA 764
Query: 272 LYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 320
LY FE + +++F +GD I V KT W G +G G FP NYV
Sbjct: 765 LYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYV 813
Score = 40.0 bits (92), Expect = 0.003
Identities = 20/61 (32%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Query: 260 QSNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANY 319
Q + + ++ AL S+ ++ LNF D ITV+ + ++ WW G++ G G FP +Y
Sbjct: 894 QGQVVENLKAQALCSWTAKKDNHLNFSKHDIITVLEQQEN---WWFGEVHGGRGWFPKSY 950
Query: 320 V 320
V
Sbjct: 951 V 951
>gi|21450838 SH3 and cysteine rich domain 3 [Homo sapiens]
Length = 364
Score = 54.7 bits (130), Expect = 1e-07
Identities = 32/113 (28%), Positives = 52/113 (46%), Gaps = 6/113 (5%)
Query: 212 EKYENEGQRINARKAAREQRKSSAKELPPKPLSRPQQSSAPVQLNSGS----QSNLNQPI 267
E+ + + + N A E+ SA+ KP + + + Q Q
Sbjct: 191 ERKKGQADKKNPVAAMMEEEPESARPEEGKPQDGNPEGDKKAEKKTPDDKHKQPGFQQSH 250
Query: 268 EVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 320
ALY F+ + DL+F G++ITVI DS+ +WW GK+ + G FP N++
Sbjct: 251 YFVALYRFKALEKDDLDFPPGEKITVID--DSNEEWWRGKIGEKVGFFPPNFI 301
>gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo
sapiens]
Length = 756
Score = 54.3 bits (129), Expect = 1e-07
Identities = 25/81 (30%), Positives = 41/81 (50%)
Query: 240 PKPLSRPQQSSAPVQLNSGSQSNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDS 299
P P P+ SS ++ P L+ ++ + P +L + GD + V+SKT
Sbjct: 157 PGPQRPPKLSSLAYDSPPDYLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTE 216
Query: 300 HFDWWEGKLRGQTGIFPANYV 320
WWEG+ +G+ G+FP N+V
Sbjct: 217 DKGWWEGECQGRRGVFPDNFV 237
Score = 42.7 bits (99), Expect = 4e-04
Identities = 18/50 (36%), Positives = 30/50 (60%), Gaps = 2/50 (4%)
Query: 273 YSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTM 322
+S+ +Q +L QAG+ + +I + + WW GK GQ G FP+N+V +
Sbjct: 92 FSYSPEQADELKLQAGEIVEMIKEIED--GWWLGKKNGQLGAFPSNFVEL 139
>gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [Homo
sapiens]
Length = 645
Score = 54.3 bits (129), Expect = 1e-07
Identities = 25/81 (30%), Positives = 41/81 (50%)
Query: 240 PKPLSRPQQSSAPVQLNSGSQSNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDS 299
P P P+ SS ++ P L+ ++ + P +L + GD + V+SKT
Sbjct: 46 PGPQRPPKLSSLAYDSPPDYLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTE 105
Query: 300 HFDWWEGKLRGQTGIFPANYV 320
WWEG+ +G+ G+FP N+V
Sbjct: 106 DKGWWEGECQGRRGVFPDNFV 126
Score = 32.0 bits (71), Expect = 0.76
Identities = 11/20 (55%), Positives = 14/20 (70%)
Query: 303 WWEGKLRGQTGIFPANYVTM 322
WW GK GQ G FP+N+V +
Sbjct: 9 WWLGKKNGQLGAFPSNFVEL 28
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 53.9 bits (128), Expect = 2e-07
Identities = 24/55 (43%), Positives = 33/55 (60%), Gaps = 3/55 (5%)
Query: 268 EVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTM 322
E A+Y++E + GDL FQ GD I V K DWW G + + G+FP+NYV +
Sbjct: 1006 EFIAMYTYESSEQGDLTFQQGDVILVTKKDG---DWWTGTVGDKAGVFPSNYVRL 1057
Score = 53.1 bits (126), Expect = 3e-07
Identities = 22/55 (40%), Positives = 34/55 (61%), Gaps = 2/55 (3%)
Query: 268 EVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTM 322
+V +Y + Q +L F G I V++K D DWW+G++ GQ G+FP+NYV +
Sbjct: 1159 QVIGMYDYTAQNDDELAFNKGQIINVLNKEDP--DWWKGEVNGQVGLFPSNYVKL 1211
Score = 46.6 bits (109), Expect = 3e-05
Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 7/81 (8%)
Query: 242 PLSRPQQSSAPVQLNSGSQSNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHF 301
P + S +PV Q + ++ ALY + ++ LNF D ITV+ + D
Sbjct: 895 PATATGSSPSPVL----GQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDM-- 948
Query: 302 DWWEGKLRGQTGIFPANYVTM 322
WW G+++GQ G FP +YV +
Sbjct: 949 -WWFGEVQGQKGWFPKSYVKL 968
Score = 41.2 bits (95), Expect = 0.001
Identities = 35/137 (25%), Positives = 60/137 (43%), Gaps = 17/137 (12%)
Query: 199 QAEDLYEILDSFTEKYENEGQRINARKAAREQRKSSAKEL----------PPKP-LSRPQ 247
Q ED ++ E+ + + + +K E+ K A++ P KP + P
Sbjct: 665 QQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAVQAPW 724
Query: 248 QSSAPVQLNSGSQSNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFD----- 302
++ L +Q N+ + + ALY FE + ++ Q GD + V +
Sbjct: 725 STAEKGPLTISAQENV-KVVYYRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPG 783
Query: 303 WWEGKLRGQTGIFPANY 319
W G+L+G+TG FPANY
Sbjct: 784 WLGGELKGKTGWFPANY 800
Score = 34.3 bits (77), Expect = 0.15
Identities = 24/71 (33%), Positives = 32/71 (45%), Gaps = 9/71 (12%)
Query: 257 SGSQSNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRG-----Q 311
+GS + +V A Y+ G P L G I + K WWEG+L+ Q
Sbjct: 1069 TGSLGKKPEIAQVIASYTATG--PEQLTLAPGQLILIRKKNPG--GWWEGELQARGKKRQ 1124
Query: 312 TGIFPANYVTM 322
G FPANYV +
Sbjct: 1125 IGWFPANYVKL 1135
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 53.9 bits (128), Expect = 2e-07
Identities = 24/55 (43%), Positives = 33/55 (60%), Gaps = 3/55 (5%)
Query: 268 EVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTM 322
E A+Y++E + GDL FQ GD I V K DWW G + + G+FP+NYV +
Sbjct: 1006 EFIAMYTYESSEQGDLTFQQGDVILVTKKDG---DWWTGTVGDKAGVFPSNYVRL 1057
Score = 53.1 bits (126), Expect = 3e-07
Identities = 22/55 (40%), Positives = 34/55 (61%), Gaps = 2/55 (3%)
Query: 268 EVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTM 322
+V +Y + Q +L F G I V++K D DWW+G++ GQ G+FP+NYV +
Sbjct: 1159 QVIGMYDYTAQNDDELAFNKGQIINVLNKEDP--DWWKGEVNGQVGLFPSNYVKL 1211
Score = 46.6 bits (109), Expect = 3e-05
Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 7/81 (8%)
Query: 242 PLSRPQQSSAPVQLNSGSQSNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHF 301
P + S +PV Q + ++ ALY + ++ LNF D ITV+ + D
Sbjct: 895 PATATGSSPSPVL----GQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDM-- 948
Query: 302 DWWEGKLRGQTGIFPANYVTM 322
WW G+++GQ G FP +YV +
Sbjct: 949 -WWFGEVQGQKGWFPKSYVKL 968
Score = 41.2 bits (95), Expect = 0.001
Identities = 35/137 (25%), Positives = 60/137 (43%), Gaps = 17/137 (12%)
Query: 199 QAEDLYEILDSFTEKYENEGQRINARKAAREQRKSSAKEL----------PPKP-LSRPQ 247
Q ED ++ E+ + + + +K E+ K A++ P KP + P
Sbjct: 665 QQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAVQAPW 724
Query: 248 QSSAPVQLNSGSQSNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFD----- 302
++ L +Q N+ + + ALY FE + ++ Q GD + V +
Sbjct: 725 STAEKGPLTISAQENV-KVVYYRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPG 783
Query: 303 WWEGKLRGQTGIFPANY 319
W G+L+G+TG FPANY
Sbjct: 784 WLGGELKGKTGWFPANY 800
Score = 34.3 bits (77), Expect = 0.15
Identities = 24/71 (33%), Positives = 32/71 (45%), Gaps = 9/71 (12%)
Query: 257 SGSQSNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRG-----Q 311
+GS + +V A Y+ G P L G I + K WWEG+L+ Q
Sbjct: 1069 TGSLGKKPEIAQVIASYTATG--PEQLTLAPGQLILIRKKNPG--GWWEGELQARGKKRQ 1124
Query: 312 TGIFPANYVTM 322
G FPANYV +
Sbjct: 1125 IGWFPANYVKL 1135
>gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens]
Length = 731
Score = 53.9 bits (128), Expect = 2e-07
Identities = 24/50 (48%), Positives = 33/50 (66%), Gaps = 2/50 (4%)
Query: 271 ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 320
ALY F G+ +L+F+AGD IT + D DW G+L G++GIFP NY+
Sbjct: 678 ALYDFRGENEDELSFKAGDIITELESVDD--DWMSGELMGKSGIFPKNYI 725
Score = 53.5 bits (127), Expect = 2e-07
Identities = 30/67 (44%), Positives = 43/67 (64%), Gaps = 4/67 (5%)
Query: 256 NSGSQSNLNQ-PIE-VTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTG 313
+SGS S +N P E AL+SF + DL+F+ GDRI ++ + DS DW G+L+ + G
Sbjct: 592 DSGSNSQVNSLPAEWCEALHSFTAETSDDLSFKRGDRIQILERLDS--DWCRGRLQDREG 649
Query: 314 IFPANYV 320
IFPA +V
Sbjct: 650 IFPAVFV 656
Score = 49.3 bits (116), Expect = 5e-06
Identities = 25/65 (38%), Positives = 38/65 (58%), Gaps = 7/65 (10%)
Query: 261 SNLNQPIEVTA-----LYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIF 315
S+ +P++ A L+ F +Q DLN +G+ + ++ K D+ DW+ G R Q GIF
Sbjct: 428 SHAQKPVDSGAPHAVVLHDFPAEQVDDLNLTSGEIVYLLEKIDT--DWYRGNCRNQIGIF 485
Query: 316 PANYV 320
PANYV
Sbjct: 486 PANYV 490
Score = 40.8 bits (94), Expect = 0.002
Identities = 19/50 (38%), Positives = 32/50 (64%), Gaps = 2/50 (4%)
Query: 271 ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 320
A + + G+Q +L+F G+ +I K + +W G++RG+TGIFP N+V
Sbjct: 519 ARFEYIGEQKDELSFSEGE--IIILKEYVNEEWARGEVRGRTGIFPLNFV 566
>gi|193083143 SH3 domain containing 19 isoform b [Homo sapiens]
Length = 767
Score = 53.9 bits (128), Expect = 2e-07
Identities = 24/50 (48%), Positives = 33/50 (66%), Gaps = 2/50 (4%)
Query: 271 ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 320
ALY F G+ +L+F+AGD IT + D DW G+L G++GIFP NY+
Sbjct: 714 ALYDFRGENEDELSFKAGDIITELESVDD--DWMSGELMGKSGIFPKNYI 761
Score = 53.5 bits (127), Expect = 2e-07
Identities = 30/67 (44%), Positives = 43/67 (64%), Gaps = 4/67 (5%)
Query: 256 NSGSQSNLNQ-PIE-VTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTG 313
+SGS S +N P E AL+SF + DL+F+ GDRI ++ + DS DW G+L+ + G
Sbjct: 628 DSGSNSQVNSLPAEWCEALHSFTAETSDDLSFKRGDRIQILERLDS--DWCRGRLQDREG 685
Query: 314 IFPANYV 320
IFPA +V
Sbjct: 686 IFPAVFV 692
Score = 49.3 bits (116), Expect = 5e-06
Identities = 25/65 (38%), Positives = 38/65 (58%), Gaps = 7/65 (10%)
Query: 261 SNLNQPIEVTA-----LYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIF 315
S+ +P++ A L+ F +Q DLN +G+ + ++ K D+ DW+ G R Q GIF
Sbjct: 464 SHAQKPVDSGAPHAVVLHDFPAEQVDDLNLTSGEIVYLLEKIDT--DWYRGNCRNQIGIF 521
Query: 316 PANYV 320
PANYV
Sbjct: 522 PANYV 526
Score = 40.8 bits (94), Expect = 0.002
Identities = 19/50 (38%), Positives = 32/50 (64%), Gaps = 2/50 (4%)
Query: 271 ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 320
A + + G+Q +L+F G+ +I K + +W G++RG+TGIFP N+V
Sbjct: 555 ARFEYIGEQKDELSFSEGE--IIILKEYVNEEWARGEVRGRTGIFPLNFV 602
>gi|193083141 SH3 domain containing 19 isoform a [Homo sapiens]
Length = 790
Score = 53.9 bits (128), Expect = 2e-07
Identities = 24/50 (48%), Positives = 33/50 (66%), Gaps = 2/50 (4%)
Query: 271 ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 320
ALY F G+ +L+F+AGD IT + D DW G+L G++GIFP NY+
Sbjct: 737 ALYDFRGENEDELSFKAGDIITELESVDD--DWMSGELMGKSGIFPKNYI 784
Score = 53.5 bits (127), Expect = 2e-07
Identities = 30/67 (44%), Positives = 43/67 (64%), Gaps = 4/67 (5%)
Query: 256 NSGSQSNLNQ-PIE-VTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTG 313
+SGS S +N P E AL+SF + DL+F+ GDRI ++ + DS DW G+L+ + G
Sbjct: 651 DSGSNSQVNSLPAEWCEALHSFTAETSDDLSFKRGDRIQILERLDS--DWCRGRLQDREG 708
Query: 314 IFPANYV 320
IFPA +V
Sbjct: 709 IFPAVFV 715
Score = 49.3 bits (116), Expect = 5e-06
Identities = 25/65 (38%), Positives = 38/65 (58%), Gaps = 7/65 (10%)
Query: 261 SNLNQPIEVTA-----LYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIF 315
S+ +P++ A L+ F +Q DLN +G+ + ++ K D+ DW+ G R Q GIF
Sbjct: 487 SHAQKPVDSGAPHAVVLHDFPAEQVDDLNLTSGEIVYLLEKIDT--DWYRGNCRNQIGIF 544
Query: 316 PANYV 320
PANYV
Sbjct: 545 PANYV 549
Score = 40.8 bits (94), Expect = 0.002
Identities = 19/50 (38%), Positives = 32/50 (64%), Gaps = 2/50 (4%)
Query: 271 ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 320
A + + G+Q +L+F G+ +I K + +W G++RG+TGIFP N+V
Sbjct: 578 ARFEYIGEQKDELSFSEGE--IIILKEYVNEEWARGEVRGRTGIFPLNFV 625
>gi|150010572 SH3 domain containing ring finger 3 [Homo sapiens]
Length = 882
Score = 53.9 bits (128), Expect = 2e-07
Identities = 24/50 (48%), Positives = 32/50 (64%), Gaps = 2/50 (4%)
Query: 271 ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 320
ALYS+EG++PGDL F GD I + K D W+ G+L G G PA+Y+
Sbjct: 201 ALYSYEGKEPGDLKFNKGDIIVLRRKVDE--QWYHGELHGTQGFLPASYI 248
Score = 40.4 bits (93), Expect = 0.002
Identities = 32/99 (32%), Positives = 49/99 (49%), Gaps = 9/99 (9%)
Query: 226 AAREQRKSSAKELPPKPLSRPQQSSAPVQLNSGSQSNLNQPIEV-TALYSFEGQQPGDLN 284
AA Q SS+ P + R +A V G+ + P+ V ALY+++ Q+ +L
Sbjct: 429 AAPTQDVSSSAGSTPTAVPR----AASVSGEQGTPPKVQLPLNVYLALYAYKPQKSDELE 484
Query: 285 FQAGDRITVISKTDSHFDWWEG-KLR-GQTGIFPANYVT 321
G+ V+ K W++G LR G +G+FP NYVT
Sbjct: 485 LHKGEMYRVLEKCQD--GWFKGASLRTGVSGVFPGNYVT 521
Score = 36.2 bits (82), Expect = 0.040
Identities = 23/62 (37%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 266 PIEVTALYSFE----GQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVT 321
P + ALY FE Q L F + +TV+ + D + W EG L + GIFP YV
Sbjct: 258 PPQGKALYDFEMKDKDQDKDCLTFTKDEILTVLRRVDEN--WAEGMLGDKIGIFPLLYVE 315
Query: 322 MN 323
+N
Sbjct: 316 LN 317
Score = 30.4 bits (67), Expect = 2.2
Identities = 15/49 (30%), Positives = 28/49 (57%), Gaps = 4/49 (8%)
Query: 274 SFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLR--GQTGIFPANYV 320
S+ Q ++ + GD + V K + W++G L+ G+TG+FP ++V
Sbjct: 833 SYPPQSEAEIELKEGDIVFVHKKRED--GWYKGTLQRNGRTGLFPGSFV 879
>gi|4507249 signal transducing adaptor molecule 1 [Homo sapiens]
Length = 540
Score = 53.5 bits (127), Expect = 2e-07
Identities = 32/100 (32%), Positives = 55/100 (55%), Gaps = 6/100 (6%)
Query: 226 AAREQRKSSAKELPPKPLSRPQQSSAPVQLNSGSQSNL----NQPIEVTALYSFEGQQPG 281
A +++ + AK + + QQS+ L + S L ++ +V A+Y FE +
Sbjct: 168 ANKKEEEDLAKAIELSLKEQRQQSTTLSTLYPSTSSLLTNHQHEGRKVRAIYDFEAAEDN 227
Query: 282 DLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVT 321
+L F+AG+ ITV+ DS +WW+G+ G+FP+N+VT
Sbjct: 228 ELTFKAGEIITVLD--DSDPNWWKGETHQGIGLFPSNFVT 265
>gi|188219625 signal transducing adaptor molecule 2 [Homo sapiens]
Length = 525
Score = 53.5 bits (127), Expect = 2e-07
Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 4/91 (4%)
Query: 235 AKELPPKPLSRPQQSSAPVQLNSGSQSNLNQPI--EVTALYSFEGQQPGDLNFQAGDRIT 292
AK + + QQ + L S+ LN + +V ALY FE + +L F+ G+ I
Sbjct: 171 AKAIELSLQEQKQQHTETKSLYPSSEIQLNNKVARKVRALYDFEAVEDNELTFKHGEIII 230
Query: 293 VISKTDSHFDWWEGKLRGQTGIFPANYVTMN 323
V+ +D++ WW+G+ G+FP+N+VT N
Sbjct: 231 VLDDSDAN--WWKGENHRGIGLFPSNFVTTN 259
>gi|51988887 SH3 domain containing ring finger 1 [Homo sapiens]
Length = 888
Score = 53.5 bits (127), Expect = 2e-07
Identities = 36/104 (34%), Positives = 49/104 (47%), Gaps = 4/104 (3%)
Query: 218 GQRINARKAAREQRKSSAKELPPKPLSRPQQSSAP-VQLNSGSQSNLNQPIEVTALYSFE 276
G N A R Q S+ K L Q P VQ S + Q ALY++E
Sbjct: 88 GSGTNCTNALRSQ-SSTVANCSSKDLQSSQGGQQPRVQSWSPPVRGIPQLPCAKALYNYE 146
Query: 277 GQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 320
G++PGDL F GD I + + D +W+ G++ G G FP N+V
Sbjct: 147 GKEPGDLKFSKGDIIILRRQVDE--NWYHGEVNGIHGFFPTNFV 188
Score = 37.4 bits (85), Expect = 0.018
Identities = 24/62 (38%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 266 PIEVTALYSFEGQQPGD----LNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVT 321
P + ALY FE + L F D +TVI + D + W EG L + GIFP +YV
Sbjct: 198 PPQCKALYDFEVKDKEADKDCLPFAKDDVLTVIRRVDEN--WAEGMLADKIGIFPISYVE 255
Query: 322 MN 323
N
Sbjct: 256 FN 257
Score = 30.8 bits (68), Expect = 1.7
Identities = 16/49 (32%), Positives = 28/49 (57%), Gaps = 4/49 (8%)
Query: 274 SFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLR--GQTGIFPANYV 320
S+ Q +L + GD + V K + W++G L+ G+TG+FP ++V
Sbjct: 839 SYPPQSEAELELKEGDIVFVHKKRED--GWFKGTLQRNGKTGLFPGSFV 885
>gi|148747351 protein kinase C and casein kinase substrate in
neurons 2 [Homo sapiens]
Length = 486
Score = 53.1 bits (126), Expect = 3e-07
Identities = 25/55 (45%), Positives = 37/55 (67%), Gaps = 2/55 (3%)
Query: 267 IEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKL-RGQTGIFPANYV 320
+ V ALY +EGQ+ +L+F+AGD +T + D W +G+L GQ G++PANYV
Sbjct: 429 VRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQ-GWCKGRLDNGQVGLYPANYV 482
>gi|4507247 SH3 and cysteine rich domain [Homo sapiens]
Length = 402
Score = 53.1 bits (126), Expect = 3e-07
Identities = 37/128 (28%), Positives = 56/128 (43%), Gaps = 11/128 (8%)
Query: 193 DTPRPAQAEDLYEILDSFTEKYENEGQRINARKAAREQRKSSAKELPPKPLSRPQQSSAP 252
D+P DL E+ E+ G + RK R +S P + +
Sbjct: 223 DSPHRTSTSDLVEV----PEEANGPGGGYDLRK-----RSNSVFTYPENGTDDFRDPAKN 273
Query: 253 VQLNSGSQSNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQT 312
+ + Q ALY F Q+ DL + GD IT++ DS+ DWW+GK++ +
Sbjct: 274 INHQGSLSKDPLQMNTYVALYKFVPQENEDLEMRPGDIITLLE--DSNEDWWKGKIQDRI 331
Query: 313 GIFPANYV 320
G FPAN+V
Sbjct: 332 GFFPANFV 339
>gi|115527076 src kinase associated phosphoprotein 1 isoform 2 [Homo
sapiens]
Length = 358
Score = 52.8 bits (125), Expect = 4e-07
Identities = 34/150 (22%), Positives = 63/150 (42%), Gaps = 13/150 (8%)
Query: 179 FYCQDIRAYDILFGDTPRPAQAEDLYEILDSFTEKYENEGQR-------INARKAAREQR 231
F +D+ + I + + + E+ Y+ +D F R + ++ E+
Sbjct: 207 FLLKDLSSLTIPYEEDEEEEEKEETYDDIDGFDSPSCGSQCRPTILPGSVGIKEPTEEKE 266
Query: 232 KSSAKELPPKPLSRPQQSSAPVQLNSGSQSNLNQPIEVTALYSFEGQQPGDLNFQAGDRI 291
+ E+ P ++ SG++ + L+ G QP +L+FQ GD I
Sbjct: 267 EEDIYEVLPDEEHDLEEDE------SGTRRKGDYASYYQGLWDCHGDQPDELSFQRGDLI 320
Query: 292 TVISKTDSHFDWWEGKLRGQTGIFPANYVT 321
++SK + + WW G+L GI P Y+T
Sbjct: 321 RILSKEYNMYGWWVGELNSLVGIVPKEYLT 350
>gi|24308229 protein kinase C and casein kinase substrate in neurons
1 [Homo sapiens]
Length = 444
Score = 52.4 bits (124), Expect = 5e-07
Identities = 24/55 (43%), Positives = 37/55 (67%), Gaps = 2/55 (3%)
Query: 267 IEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKL-RGQTGIFPANYV 320
+ V ALY ++GQ+ +L+F+AGD +T + + D W G+L GQ G++PANYV
Sbjct: 388 VRVRALYDYDGQEQDELSFKAGDELTKLGEEDEQ-GWCRGRLDSGQLGLYPANYV 441
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,032,181
Number of Sequences: 37866
Number of extensions: 537800
Number of successful extensions: 2532
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 136
Number of HSP's successfully gapped in prelim test: 112
Number of HSP's that attempted gapping in prelim test: 2146
Number of HSP's gapped (non-prelim): 372
length of query: 323
length of database: 18,247,518
effective HSP length: 102
effective length of query: 221
effective length of database: 14,385,186
effective search space: 3179126106
effective search space used: 3179126106
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.