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Search of human proteins with 227430336
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|227430336 SH3 domain containing, Ysc84-like 1 isoform 1
[Homo sapiens]
(342 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|227430336 SH3 domain containing, Ysc84-like 1 isoform 1 [Homo... 681 0.0
gi|227430338 SH3 domain containing, Ysc84-like 1 isoform 2 [Homo... 629 e-180
gi|4504111 growth factor receptor-bound protein 2 isoform 1 [Hom... 61 1e-09
gi|45359859 growth factor receptor-bound protein 2 isoform 2 [Ho... 61 1e-09
gi|4506929 SH3-domain GRB2-like 1 [Homo sapiens] 59 5e-09
gi|4507249 signal transducing adaptor molecule 1 [Homo sapiens] 56 4e-08
gi|223468657 SH3-domain GRB2-like 3 [Homo sapiens] 56 5e-08
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 55 9e-08
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 55 9e-08
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 55 9e-08
gi|189083742 neutrophil cytosolic factor 2 [Homo sapiens] 55 1e-07
gi|67189970 neutrophil cytosolic factor 2 [Homo sapiens] 55 1e-07
gi|21450838 SH3 and cysteine rich domain 3 [Homo sapiens] 55 1e-07
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 54 2e-07
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 54 2e-07
gi|148747351 protein kinase C and casein kinase substrate in neu... 54 2e-07
gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens] 54 2e-07
gi|193083143 SH3 domain containing 19 isoform b [Homo sapiens] 54 2e-07
gi|193083141 SH3 domain containing 19 isoform a [Homo sapiens] 54 2e-07
gi|150010572 SH3 domain containing ring finger 3 [Homo sapiens] 54 2e-07
gi|55956916 myosin IE [Homo sapiens] 54 2e-07
gi|39752673 SH3 and cysteine rich domain 2 [Homo sapiens] 54 2e-07
gi|188219625 signal transducing adaptor molecule 2 [Homo sapiens] 53 3e-07
gi|4507247 SH3 and cysteine rich domain [Homo sapiens] 53 3e-07
gi|51988887 SH3 domain containing ring finger 1 [Homo sapiens] 53 3e-07
gi|4506931 SH3-domain GRB2-like 2 [Homo sapiens] 53 5e-07
gi|89886447 nitric oxide synthase trafficker isoform 2 [Homo sap... 52 6e-07
gi|16418431 nitric oxide synthase trafficker isoform 1 [Homo sap... 52 6e-07
gi|166064036 PAK-interacting exchange factor beta isoform d [Hom... 52 6e-07
gi|166064034 PAK-interacting exchange factor beta isoform c [Hom... 52 6e-07
>gi|227430336 SH3 domain containing, Ysc84-like 1 isoform 1 [Homo
sapiens]
Length = 342
Score = 681 bits (1756), Expect = 0.0
Identities = 342/342 (100%), Positives = 342/342 (100%)
Query: 1 MNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAILSVIKAGFLVT 60
MNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAILSVIKAGFLVT
Sbjct: 1 MNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAILSVIKAGFLVT 60
Query: 61 ARGGSGIVVARLPDGKWSAPSAIGIAGLGGGFEIGIEVSDLVIILNYDRAVEAFAKGGNL 120
ARGGSGIVVARLPDGKWSAPSAIGIAGLGGGFEIGIEVSDLVIILNYDRAVEAFAKGGNL
Sbjct: 61 ARGGSGIVVARLPDGKWSAPSAIGIAGLGGGFEIGIEVSDLVIILNYDRAVEAFAKGGNL 120
Query: 121 TLGGNLTVAVGPLGRNLEGNVALRSSAAVFTYCKSRGLFAGVSLEGSCLIERKETNRKFY 180
TLGGNLTVAVGPLGRNLEGNVALRSSAAVFTYCKSRGLFAGVSLEGSCLIERKETNRKFY
Sbjct: 121 TLGGNLTVAVGPLGRNLEGNVALRSSAAVFTYCKSRGLFAGVSLEGSCLIERKETNRKFY 180
Query: 181 CQDIRAYDILFGDTPRPAQAEDLYEILDSFTEKYENEGQRINARKAAREQRKSSAKELPP 240
CQDIRAYDILFGDTPRPAQAEDLYEILDSFTEKYENEGQRINARKAAREQRKSSAKELPP
Sbjct: 181 CQDIRAYDILFGDTPRPAQAEDLYEILDSFTEKYENEGQRINARKAAREQRKSSAKELPP 240
Query: 241 KPLSRPQQSSAPVQLNSGSQSNRNEYKLYPGLSSYHERVGNLNQPIEVTALYSFEGQQPG 300
KPLSRPQQSSAPVQLNSGSQSNRNEYKLYPGLSSYHERVGNLNQPIEVTALYSFEGQQPG
Sbjct: 241 KPLSRPQQSSAPVQLNSGSQSNRNEYKLYPGLSSYHERVGNLNQPIEVTALYSFEGQQPG 300
Query: 301 DLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTMN 342
DLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTMN
Sbjct: 301 DLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTMN 342
>gi|227430338 SH3 domain containing, Ysc84-like 1 isoform 2 [Homo
sapiens]
Length = 323
Score = 629 bits (1621), Expect = e-180
Identities = 323/342 (94%), Positives = 323/342 (94%), Gaps = 19/342 (5%)
Query: 1 MNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAILSVIKAGFLVT 60
MNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAILSVIKAGFLVT
Sbjct: 1 MNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAILSVIKAGFLVT 60
Query: 61 ARGGSGIVVARLPDGKWSAPSAIGIAGLGGGFEIGIEVSDLVIILNYDRAVEAFAKGGNL 120
ARGGSGIVVARLPDGKWSAPSAIGIAGLGGGFEIGIEVSDLVIILNYDRAVEAFAKGGNL
Sbjct: 61 ARGGSGIVVARLPDGKWSAPSAIGIAGLGGGFEIGIEVSDLVIILNYDRAVEAFAKGGNL 120
Query: 121 TLGGNLTVAVGPLGRNLEGNVALRSSAAVFTYCKSRGLFAGVSLEGSCLIERKETNRKFY 180
TLGGNLTVAVGPLGRNLEGNVALRSSAAVFTYCKSRGLFAGVSLEGSCLIERKETNRKFY
Sbjct: 121 TLGGNLTVAVGPLGRNLEGNVALRSSAAVFTYCKSRGLFAGVSLEGSCLIERKETNRKFY 180
Query: 181 CQDIRAYDILFGDTPRPAQAEDLYEILDSFTEKYENEGQRINARKAAREQRKSSAKELPP 240
CQDIRAYDILFGDTPRPAQAEDLYEILDSFTEKYENEGQRINARKAAREQRKSSAKELPP
Sbjct: 181 CQDIRAYDILFGDTPRPAQAEDLYEILDSFTEKYENEGQRINARKAAREQRKSSAKELPP 240
Query: 241 KPLSRPQQSSAPVQLNSGSQSNRNEYKLYPGLSSYHERVGNLNQPIEVTALYSFEGQQPG 300
KPLSRPQQSSAPVQLNSGSQS NLNQPIEVTALYSFEGQQPG
Sbjct: 241 KPLSRPQQSSAPVQLNSGSQS-------------------NLNQPIEVTALYSFEGQQPG 281
Query: 301 DLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTMN 342
DLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTMN
Sbjct: 282 DLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTMN 323
>gi|4504111 growth factor receptor-bound protein 2 isoform 1 [Homo
sapiens]
Length = 217
Score = 61.2 bits (147), Expect = 1e-09
Identities = 28/57 (49%), Positives = 38/57 (66%), Gaps = 2/57 (3%)
Query: 284 QPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVT 340
QP V AL+ F+ Q+ G+L F+ GD I V+ +D + WW+G GQTG+FP NYVT
Sbjct: 157 QPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPN--WWKGACHGQTGMFPRNYVT 211
Score = 39.7 bits (91), Expect = 0.004
Identities = 17/56 (30%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Query: 286 IEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTM 341
+E A Y F+ +L+F+ GD + V+++ + +W++ +L G+ G P NY+ M
Sbjct: 1 MEAIAKYDFKATADDELSFKRGDILKVLNE-ECDQNWYKAELNGKDGFIPKNYIEM 55
>gi|45359859 growth factor receptor-bound protein 2 isoform 2 [Homo
sapiens]
Length = 176
Score = 61.2 bits (147), Expect = 1e-09
Identities = 28/57 (49%), Positives = 38/57 (66%), Gaps = 2/57 (3%)
Query: 284 QPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVT 340
QP V AL+ F+ Q+ G+L F+ GD I V+ +D + WW+G GQTG+FP NYVT
Sbjct: 116 QPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPN--WWKGACHGQTGMFPRNYVT 170
Score = 39.7 bits (91), Expect = 0.004
Identities = 17/56 (30%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Query: 286 IEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTM 341
+E A Y F+ +L+F+ GD + V+++ + +W++ +L G+ G P NY+ M
Sbjct: 1 MEAIAKYDFKATADDELSFKRGDILKVLNE-ECDQNWYKAELNGKDGFIPKNYIEM 55
>gi|4506929 SH3-domain GRB2-like 1 [Homo sapiens]
Length = 368
Score = 59.3 bits (142), Expect = 5e-09
Identities = 45/140 (32%), Positives = 68/140 (48%), Gaps = 15/140 (10%)
Query: 205 EILDSFTEKYENEGQRINARKAAREQRKSSAKELPPKPLSRPQQSSAPVQLNSG-----S 259
+ILD EK + R ++R +R+ K P L P+QS+ + S
Sbjct: 231 QILDELAEKLK----RRMREASSRPKREYKPKPREPFDLGEPEQSNGGFPCTTAPKIAAS 286
Query: 260 QSNRNEYKLYPGLSSYHERVGNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSH 319
S R+ K + + + L+QP ALY FE + G+L F GD IT+ ++ D
Sbjct: 287 SSFRSSDK---PIRTPSRSMPPLDQP-SCKALYDFEPENDGELGFHEGDVITLTNQIDE- 341
Query: 320 FDWWEGKLRGQTGIFPANYV 339
+W+EG L GQ+G FP +YV
Sbjct: 342 -NWYEGMLDGQSGFFPLSYV 360
>gi|4507249 signal transducing adaptor molecule 1 [Homo sapiens]
Length = 540
Score = 56.2 bits (134), Expect = 4e-08
Identities = 44/171 (25%), Positives = 80/171 (46%), Gaps = 34/171 (19%)
Query: 197 PAQAEDLYEILDSFTEKYENEGQR--INARKAAREQRKSSAKELPPKPLSRPQQSSAPVQ 254
P E L ++ +T++++N+ Q I+A +++ + + + + + S A V
Sbjct: 102 PKVCEKLKALMVEWTDEFKNDPQLSLISAMIKNLKEQGVTFPAIGSQAAEQAKASPALVA 161
Query: 255 LNSGSQSNRNEYK----------------------LYPGLSSY---HERVGNLNQPIEVT 289
+ G+ +N+ E + LYP SS H+ G +V
Sbjct: 162 KDPGTVANKKEEEDLAKAIELSLKEQRQQSTTLSTLYPSTSSLLTNHQHEGR-----KVR 216
Query: 290 ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVT 340
A+Y FE + +L F+AG+ ITV+ DS +WW+G+ G+FP+N+VT
Sbjct: 217 AIYDFEAAEDNELTFKAGEIITVLD--DSDPNWWKGETHQGIGLFPSNFVT 265
>gi|223468657 SH3-domain GRB2-like 3 [Homo sapiens]
Length = 347
Score = 55.8 bits (133), Expect = 5e-08
Identities = 35/105 (33%), Positives = 53/105 (50%), Gaps = 15/105 (14%)
Query: 248 QSSAPVQLNSGSQSNRNEYKLYPGLSSYHERVG----------NLNQPIE---VTALYSF 294
QS +++++ S R EYK P S E G N P++ LY F
Sbjct: 237 QSKLQMRISAASSVPRREYKPRPVKRSSSELNGVSTTSVVKTTGSNIPMDQPCCRGLYDF 296
Query: 295 EGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
E + G+L F+ GD IT+ ++ D + W+EG + G++G FP NYV
Sbjct: 297 EPENQGELGFKEGDIITLTNQIDEN--WYEGMIHGESGFFPINYV 339
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 55.1 bits (131), Expect = 9e-08
Identities = 23/55 (41%), Positives = 35/55 (63%), Gaps = 2/55 (3%)
Query: 287 EVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTM 341
+V A+Y + +L+F G I V++K D DWW+G++ G TG+FP+NYV M
Sbjct: 1104 QVIAMYDYAANNEDELSFSKGQLINVMNKDDP--DWWQGEINGVTGLFPSNYVKM 1156
Score = 51.2 bits (121), Expect = 1e-06
Identities = 23/53 (43%), Positives = 31/53 (58%), Gaps = 3/53 (5%)
Query: 287 EVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
E ALY + +PGDL F G+ I V K +WW G + ++GIFP+NYV
Sbjct: 958 EYIALYPYSSVEPGDLTFTEGEEILVTQKDG---EWWTGSIGDRSGIFPSNYV 1007
Score = 44.3 bits (103), Expect = 2e-04
Identities = 32/118 (27%), Positives = 47/118 (39%), Gaps = 11/118 (9%)
Query: 222 NARKAAREQRKSSAKELPPKPLSRPQQSSAPVQLNSGSQSNRNEYKLYPGLSSYHERVGN 281
N RK E++K +E + + ++ + Q E K E
Sbjct: 680 NLRKEEEEKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLKAEEKK--------RETASV 731
Query: 282 LNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
L + ALY FE + +++F +GD I V KT W G +G G FP NYV
Sbjct: 732 L---VNYRALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYV 786
Score = 42.0 bits (97), Expect = 8e-04
Identities = 38/136 (27%), Positives = 61/136 (44%), Gaps = 15/136 (11%)
Query: 215 ENEGQRINARKAAREQRKS-SAKELPPKPLSRPQQSSAPVQLN----------SGSQSNR 263
ENE + ++ +KA S SA +PLS Q +S N S + +
Sbjct: 793 ENE-KAVSPKKALLPPTVSLSATSTSSEPLSSNQPASVTDYQNVSFSNLTVNTSWQKKSA 851
Query: 264 NEYKLYPGLSSYHERVGNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWW 323
+ PG S G + + ++ AL S+ ++ LNF D ITV+ + ++ WW
Sbjct: 852 FTRTVSPGSVSPIHGQGQVVENLKAQALCSWTAKKDNHLNFSKHDIITVLEQQEN---WW 908
Query: 324 EGKLRGQTGIFPANYV 339
G++ G G FP +YV
Sbjct: 909 FGEVHGGRGWFPKSYV 924
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 55.1 bits (131), Expect = 9e-08
Identities = 23/55 (41%), Positives = 35/55 (63%), Gaps = 2/55 (3%)
Query: 287 EVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTM 341
+V A+Y + +L+F G I V++K D DWW+G++ G TG+FP+NYV M
Sbjct: 1131 QVIAMYDYAANNEDELSFSKGQLINVMNKDDP--DWWQGEINGVTGLFPSNYVKM 1183
Score = 51.2 bits (121), Expect = 1e-06
Identities = 23/53 (43%), Positives = 31/53 (58%), Gaps = 3/53 (5%)
Query: 287 EVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
E ALY + +PGDL F G+ I V K +WW G + ++GIFP+NYV
Sbjct: 985 EYIALYPYSSVEPGDLTFTEGEEILVTQKDG---EWWTGSIGDRSGIFPSNYV 1034
Score = 44.3 bits (103), Expect = 2e-04
Identities = 32/118 (27%), Positives = 47/118 (39%), Gaps = 11/118 (9%)
Query: 222 NARKAAREQRKSSAKELPPKPLSRPQQSSAPVQLNSGSQSNRNEYKLYPGLSSYHERVGN 281
N RK E++K +E + + ++ + Q E K E
Sbjct: 707 NLRKEEEEKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLKAEEKK--------RETASV 758
Query: 282 LNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
L + ALY FE + +++F +GD I V KT W G +G G FP NYV
Sbjct: 759 L---VNYRALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYV 813
Score = 42.0 bits (97), Expect = 8e-04
Identities = 38/136 (27%), Positives = 61/136 (44%), Gaps = 15/136 (11%)
Query: 215 ENEGQRINARKAAREQRKS-SAKELPPKPLSRPQQSSAPVQLN----------SGSQSNR 263
ENE + ++ +KA S SA +PLS Q +S N S + +
Sbjct: 820 ENE-KAVSPKKALLPPTVSLSATSTSSEPLSSNQPASVTDYQNVSFSNLTVNTSWQKKSA 878
Query: 264 NEYKLYPGLSSYHERVGNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWW 323
+ PG S G + + ++ AL S+ ++ LNF D ITV+ + ++ WW
Sbjct: 879 FTRTVSPGSVSPIHGQGQVVENLKAQALCSWTAKKDNHLNFSKHDIITVLEQQEN---WW 935
Query: 324 EGKLRGQTGIFPANYV 339
G++ G G FP +YV
Sbjct: 936 FGEVHGGRGWFPKSYV 951
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 55.1 bits (131), Expect = 9e-08
Identities = 23/55 (41%), Positives = 35/55 (63%), Gaps = 2/55 (3%)
Query: 287 EVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTM 341
+V A+Y + +L+F G I V++K D DWW+G++ G TG+FP+NYV M
Sbjct: 1131 QVIAMYDYAANNEDELSFSKGQLINVMNKDDP--DWWQGEINGVTGLFPSNYVKM 1183
Score = 51.2 bits (121), Expect = 1e-06
Identities = 23/53 (43%), Positives = 31/53 (58%), Gaps = 3/53 (5%)
Query: 287 EVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
E ALY + +PGDL F G+ I V K +WW G + ++GIFP+NYV
Sbjct: 985 EYIALYPYSSVEPGDLTFTEGEEILVTQKDG---EWWTGSIGDRSGIFPSNYV 1034
Score = 44.3 bits (103), Expect = 2e-04
Identities = 32/118 (27%), Positives = 47/118 (39%), Gaps = 11/118 (9%)
Query: 222 NARKAAREQRKSSAKELPPKPLSRPQQSSAPVQLNSGSQSNRNEYKLYPGLSSYHERVGN 281
N RK E++K +E + + ++ + Q E K E
Sbjct: 707 NLRKEEEEKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLKAEEKK--------RETASV 758
Query: 282 LNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
L + ALY FE + +++F +GD I V KT W G +G G FP NYV
Sbjct: 759 L---VNYRALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYV 813
Score = 42.0 bits (97), Expect = 8e-04
Identities = 38/136 (27%), Positives = 61/136 (44%), Gaps = 15/136 (11%)
Query: 215 ENEGQRINARKAAREQRKS-SAKELPPKPLSRPQQSSAPVQLN----------SGSQSNR 263
ENE + ++ +KA S SA +PLS Q +S N S + +
Sbjct: 820 ENE-KAVSPKKALLPPTVSLSATSTSSEPLSSNQPASVTDYQNVSFSNLTVNTSWQKKSA 878
Query: 264 NEYKLYPGLSSYHERVGNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWW 323
+ PG S G + + ++ AL S+ ++ LNF D ITV+ + ++ WW
Sbjct: 879 FTRTVSPGSVSPIHGQGQVVENLKAQALCSWTAKKDNHLNFSKHDIITVLEQQEN---WW 935
Query: 324 EGKLRGQTGIFPANYV 339
G++ G G FP +YV
Sbjct: 936 FGEVHGGRGWFPKSYV 951
>gi|189083742 neutrophil cytosolic factor 2 [Homo sapiens]
Length = 526
Score = 54.7 bits (130), Expect = 1e-07
Identities = 27/58 (46%), Positives = 38/58 (65%), Gaps = 2/58 (3%)
Query: 282 LNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
L + +V AL+S+E QP DL FQ GD I V+SK + +W EG+ +G+ GIFP +V
Sbjct: 456 LKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNE--EWLEGECKGKVGIFPKVFV 511
>gi|67189970 neutrophil cytosolic factor 2 [Homo sapiens]
Length = 526
Score = 54.7 bits (130), Expect = 1e-07
Identities = 27/58 (46%), Positives = 38/58 (65%), Gaps = 2/58 (3%)
Query: 282 LNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
L + +V AL+S+E QP DL FQ GD I V+SK + +W EG+ +G+ GIFP +V
Sbjct: 456 LKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNE--EWLEGECKGKVGIFPKVFV 511
>gi|21450838 SH3 and cysteine rich domain 3 [Homo sapiens]
Length = 364
Score = 54.7 bits (130), Expect = 1e-07
Identities = 36/128 (28%), Positives = 56/128 (43%), Gaps = 17/128 (13%)
Query: 212 EKYENEGQRINARKAAREQRKSSAKELPPKPLSRPQQSSAPVQLNSGSQSNRNEYKLYPG 271
E+ + + + N A E+ SA+ KP Q P + ++ PG
Sbjct: 191 ERKKGQADKKNPVAAMMEEEPESARPEEGKP-----QDGNPEGDKKAEKKTPDDKHKQPG 245
Query: 272 LSSYHERVGNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQT 331
H V ALY F+ + DL+F G++ITVI DS+ +WW GK+ +
Sbjct: 246 FQQSHYFV----------ALYRFKALEKDDLDFPPGEKITVID--DSNEEWWRGKIGEKV 293
Query: 332 GIFPANYV 339
G FP N++
Sbjct: 294 GFFPPNFI 301
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 53.9 bits (128), Expect = 2e-07
Identities = 24/55 (43%), Positives = 33/55 (60%), Gaps = 3/55 (5%)
Query: 287 EVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTM 341
E A+Y++E + GDL FQ GD I V K DWW G + + G+FP+NYV +
Sbjct: 1006 EFIAMYTYESSEQGDLTFQQGDVILVTKKDG---DWWTGTVGDKAGVFPSNYVRL 1057
Score = 53.1 bits (126), Expect = 3e-07
Identities = 22/55 (40%), Positives = 34/55 (61%), Gaps = 2/55 (3%)
Query: 287 EVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTM 341
+V +Y + Q +L F G I V++K D DWW+G++ GQ G+FP+NYV +
Sbjct: 1159 QVIGMYDYTAQNDDELAFNKGQIINVLNKEDP--DWWKGEVNGQVGLFPSNYVKL 1211
Score = 46.6 bits (109), Expect = 3e-05
Identities = 22/62 (35%), Positives = 35/62 (56%), Gaps = 3/62 (4%)
Query: 280 GNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
G + ++ ALY + ++ LNF D ITV+ + D WW G+++GQ G FP +YV
Sbjct: 910 GEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDM---WWFGEVQGQKGWFPKSYV 966
Query: 340 TM 341
+
Sbjct: 967 KL 968
Score = 38.5 bits (88), Expect = 0.009
Identities = 35/145 (24%), Positives = 61/145 (42%), Gaps = 14/145 (9%)
Query: 199 QAEDLYEILDSFTEKYENEGQRINARKAAREQRKSSAKELPPKPLSRPQQSSAPVQLNSG 258
Q ED ++ E+ + + + +K E+ K A++ + + Q+ + P
Sbjct: 665 QQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAVQAPW 724
Query: 259 SQSNRNEYKLYPGLSSYHERVGNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDS 318
S + + P S E V + + ALY FE + ++ Q GD + V +
Sbjct: 725 STAEKG-----PLTISAQENV----KVVYYRALYPFESRSHDEITIQPGDIVMVKGEWVD 775
Query: 319 HFD-----WWEGKLRGQTGIFPANY 338
W G+L+G+TG FPANY
Sbjct: 776 ESQTGEPGWLGGELKGKTGWFPANY 800
Score = 34.7 bits (78), Expect = 0.13
Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 8/70 (11%)
Query: 278 RVGNLNQPIEVT-ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRG-----QT 331
+ G+L + E+ + S+ P L G I + K WWEG+L+ Q
Sbjct: 1068 KTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPG--GWWEGELQARGKKRQI 1125
Query: 332 GIFPANYVTM 341
G FPANYV +
Sbjct: 1126 GWFPANYVKL 1135
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 53.9 bits (128), Expect = 2e-07
Identities = 24/55 (43%), Positives = 33/55 (60%), Gaps = 3/55 (5%)
Query: 287 EVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTM 341
E A+Y++E + GDL FQ GD I V K DWW G + + G+FP+NYV +
Sbjct: 1006 EFIAMYTYESSEQGDLTFQQGDVILVTKKDG---DWWTGTVGDKAGVFPSNYVRL 1057
Score = 53.1 bits (126), Expect = 3e-07
Identities = 22/55 (40%), Positives = 34/55 (61%), Gaps = 2/55 (3%)
Query: 287 EVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTM 341
+V +Y + Q +L F G I V++K D DWW+G++ GQ G+FP+NYV +
Sbjct: 1159 QVIGMYDYTAQNDDELAFNKGQIINVLNKEDP--DWWKGEVNGQVGLFPSNYVKL 1211
Score = 46.6 bits (109), Expect = 3e-05
Identities = 22/62 (35%), Positives = 35/62 (56%), Gaps = 3/62 (4%)
Query: 280 GNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
G + ++ ALY + ++ LNF D ITV+ + D WW G+++GQ G FP +YV
Sbjct: 910 GEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDM---WWFGEVQGQKGWFPKSYV 966
Query: 340 TM 341
+
Sbjct: 967 KL 968
Score = 38.5 bits (88), Expect = 0.009
Identities = 35/145 (24%), Positives = 61/145 (42%), Gaps = 14/145 (9%)
Query: 199 QAEDLYEILDSFTEKYENEGQRINARKAAREQRKSSAKELPPKPLSRPQQSSAPVQLNSG 258
Q ED ++ E+ + + + +K E+ K A++ + + Q+ + P
Sbjct: 665 QQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQHQEPAKPAVQAPW 724
Query: 259 SQSNRNEYKLYPGLSSYHERVGNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDS 318
S + + P S E V + + ALY FE + ++ Q GD + V +
Sbjct: 725 STAEKG-----PLTISAQENV----KVVYYRALYPFESRSHDEITIQPGDIVMVKGEWVD 775
Query: 319 HFD-----WWEGKLRGQTGIFPANY 338
W G+L+G+TG FPANY
Sbjct: 776 ESQTGEPGWLGGELKGKTGWFPANY 800
Score = 34.7 bits (78), Expect = 0.13
Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 8/70 (11%)
Query: 278 RVGNLNQPIEVT-ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRG-----QT 331
+ G+L + E+ + S+ P L G I + K WWEG+L+ Q
Sbjct: 1068 KTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPG--GWWEGELQARGKKRQI 1125
Query: 332 GIFPANYVTM 341
G FPANYV +
Sbjct: 1126 GWFPANYVKL 1135
>gi|148747351 protein kinase C and casein kinase substrate in
neurons 2 [Homo sapiens]
Length = 486
Score = 53.9 bits (128), Expect = 2e-07
Identities = 41/144 (28%), Positives = 69/144 (47%), Gaps = 13/144 (9%)
Query: 197 PAQAEDLYEILDSFTEKYENEGQRINARKAAREQRKSSAKELPPKPLSRPQQSSAPVQLN 256
PAQ+ + F ++ ++ G ++ + + + SS + K S P S N
Sbjct: 351 PAQSAQSQSSYNPFEDE-DDTGSTVSEKDDTKAKNVSSYE----KTQSYPTDWSDDESNN 405
Query: 257 SGSQSNRNEYKLYPGLSSYHERVGNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKT 316
S ++ N G S+ + + V ALY +EGQ+ +L+F+AGD +T +
Sbjct: 406 PFSSTDAN------GDSNPFDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDE 459
Query: 317 DSHFDWWEGKL-RGQTGIFPANYV 339
D W +G+L GQ G++PANYV
Sbjct: 460 DEQ-GWCKGRLDNGQVGLYPANYV 482
>gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens]
Length = 731
Score = 53.9 bits (128), Expect = 2e-07
Identities = 24/50 (48%), Positives = 33/50 (66%), Gaps = 2/50 (4%)
Query: 290 ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
ALY F G+ +L+F+AGD IT + D DW G+L G++GIFP NY+
Sbjct: 678 ALYDFRGENEDELSFKAGDIITELESVDD--DWMSGELMGKSGIFPKNYI 725
Score = 49.3 bits (116), Expect = 5e-06
Identities = 23/50 (46%), Positives = 34/50 (68%), Gaps = 2/50 (4%)
Query: 290 ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
AL+SF + DL+F+ GDRI ++ + DS DW G+L+ + GIFPA +V
Sbjct: 609 ALHSFTAETSDDLSFKRGDRIQILERLDS--DWCRGRLQDREGIFPAVFV 656
Score = 48.9 bits (115), Expect = 7e-06
Identities = 22/49 (44%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
Query: 291 LYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
L+ F +Q DLN +G+ + ++ K D+ DW+ G R Q GIFPANYV
Sbjct: 444 LHDFPAEQVDDLNLTSGEIVYLLEKIDT--DWYRGNCRNQIGIFPANYV 490
Score = 40.8 bits (94), Expect = 0.002
Identities = 19/50 (38%), Positives = 32/50 (64%), Gaps = 2/50 (4%)
Query: 290 ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
A + + G+Q +L+F G+ +I K + +W G++RG+TGIFP N+V
Sbjct: 519 ARFEYIGEQKDELSFSEGE--IIILKEYVNEEWARGEVRGRTGIFPLNFV 566
>gi|193083143 SH3 domain containing 19 isoform b [Homo sapiens]
Length = 767
Score = 53.9 bits (128), Expect = 2e-07
Identities = 24/50 (48%), Positives = 33/50 (66%), Gaps = 2/50 (4%)
Query: 290 ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
ALY F G+ +L+F+AGD IT + D DW G+L G++GIFP NY+
Sbjct: 714 ALYDFRGENEDELSFKAGDIITELESVDD--DWMSGELMGKSGIFPKNYI 761
Score = 49.3 bits (116), Expect = 5e-06
Identities = 23/50 (46%), Positives = 34/50 (68%), Gaps = 2/50 (4%)
Query: 290 ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
AL+SF + DL+F+ GDRI ++ + DS DW G+L+ + GIFPA +V
Sbjct: 645 ALHSFTAETSDDLSFKRGDRIQILERLDS--DWCRGRLQDREGIFPAVFV 692
Score = 48.9 bits (115), Expect = 7e-06
Identities = 22/49 (44%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
Query: 291 LYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
L+ F +Q DLN +G+ + ++ K D+ DW+ G R Q GIFPANYV
Sbjct: 480 LHDFPAEQVDDLNLTSGEIVYLLEKIDT--DWYRGNCRNQIGIFPANYV 526
Score = 40.8 bits (94), Expect = 0.002
Identities = 19/50 (38%), Positives = 32/50 (64%), Gaps = 2/50 (4%)
Query: 290 ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
A + + G+Q +L+F G+ +I K + +W G++RG+TGIFP N+V
Sbjct: 555 ARFEYIGEQKDELSFSEGE--IIILKEYVNEEWARGEVRGRTGIFPLNFV 602
>gi|193083141 SH3 domain containing 19 isoform a [Homo sapiens]
Length = 790
Score = 53.9 bits (128), Expect = 2e-07
Identities = 24/50 (48%), Positives = 33/50 (66%), Gaps = 2/50 (4%)
Query: 290 ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
ALY F G+ +L+F+AGD IT + D DW G+L G++GIFP NY+
Sbjct: 737 ALYDFRGENEDELSFKAGDIITELESVDD--DWMSGELMGKSGIFPKNYI 784
Score = 49.3 bits (116), Expect = 5e-06
Identities = 23/50 (46%), Positives = 34/50 (68%), Gaps = 2/50 (4%)
Query: 290 ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
AL+SF + DL+F+ GDRI ++ + DS DW G+L+ + GIFPA +V
Sbjct: 668 ALHSFTAETSDDLSFKRGDRIQILERLDS--DWCRGRLQDREGIFPAVFV 715
Score = 48.9 bits (115), Expect = 7e-06
Identities = 22/49 (44%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
Query: 291 LYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
L+ F +Q DLN +G+ + ++ K D+ DW+ G R Q GIFPANYV
Sbjct: 503 LHDFPAEQVDDLNLTSGEIVYLLEKIDT--DWYRGNCRNQIGIFPANYV 549
Score = 40.8 bits (94), Expect = 0.002
Identities = 19/50 (38%), Positives = 32/50 (64%), Gaps = 2/50 (4%)
Query: 290 ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
A + + G+Q +L+F G+ +I K + +W G++RG+TGIFP N+V
Sbjct: 578 ARFEYIGEQKDELSFSEGE--IIILKEYVNEEWARGEVRGRTGIFPLNFV 625
>gi|150010572 SH3 domain containing ring finger 3 [Homo sapiens]
Length = 882
Score = 53.9 bits (128), Expect = 2e-07
Identities = 24/50 (48%), Positives = 32/50 (64%), Gaps = 2/50 (4%)
Query: 290 ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
ALYS+EG++PGDL F GD I + K D W+ G+L G G PA+Y+
Sbjct: 201 ALYSYEGKEPGDLKFNKGDIIVLRRKVDE--QWYHGELHGTQGFLPASYI 248
Score = 36.2 bits (82), Expect = 0.044
Identities = 23/62 (37%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 285 PIEVTALYSFE----GQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVT 340
P + ALY FE Q L F + +TV+ + D + W EG L + GIFP YV
Sbjct: 258 PPQGKALYDFEMKDKDQDKDCLTFTKDEILTVLRRVDEN--WAEGMLGDKIGIFPLLYVE 315
Query: 341 MN 342
+N
Sbjct: 316 LN 317
Score = 35.8 bits (81), Expect = 0.057
Identities = 20/53 (37%), Positives = 31/53 (58%), Gaps = 4/53 (7%)
Query: 290 ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEG-KLR-GQTGIFPANYVT 340
ALY+++ Q+ +L G+ V+ K W++G LR G +G+FP NYVT
Sbjct: 471 ALYAYKPQKSDELELHKGEMYRVLEKCQD--GWFKGASLRTGVSGVFPGNYVT 521
Score = 34.3 bits (77), Expect = 0.17
Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 28/120 (23%)
Query: 246 PQQSSAPVQLNSGSQSNRNEYKLYPGLSSYHERVGNLN---------QPIEVTAL----- 291
P+ SS + +GS +E + G+ H + G+L+ P+ + A+
Sbjct: 762 PEVSSLSIHGRAGSCPIESEMQGAMGMEPLHRKAGSLDLNFTSPSRQAPLSMAAIRPEPK 821
Query: 292 ----------YSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLR--GQTGIFPANYV 339
S+ Q ++ + GD + V K + W++G L+ G+TG+FP ++V
Sbjct: 822 LLPRERYRVVVSYPPQSEAEIELKEGDIVFVHKKRED--GWYKGTLQRNGRTGLFPGSFV 879
>gi|55956916 myosin IE [Homo sapiens]
Length = 1108
Score = 53.9 bits (128), Expect = 2e-07
Identities = 24/51 (47%), Positives = 34/51 (66%), Gaps = 2/51 (3%)
Query: 290 ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVT 340
ALY+++ Q +L+F A D I +I + S WW G+LRG+ G+FP NYVT
Sbjct: 1058 ALYAYDAQDTDELSFNANDIIDIIKEDPS--GWWTGRLRGKQGLFPNNYVT 1106
>gi|39752673 SH3 and cysteine rich domain 2 [Homo sapiens]
Length = 411
Score = 53.9 bits (128), Expect = 2e-07
Identities = 25/50 (50%), Positives = 33/50 (66%), Gaps = 2/50 (4%)
Query: 290 ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
ALY F Q+ DL Q GDRI ++ DS+ DWW+GK+ + G FPAN+V
Sbjct: 299 ALYKFLPQENNDLALQPGDRIMLVD--DSNEDWWKGKIGDRVGFFPANFV 346
>gi|188219625 signal transducing adaptor molecule 2 [Homo sapiens]
Length = 525
Score = 53.1 bits (126), Expect = 3e-07
Identities = 47/203 (23%), Positives = 89/203 (43%), Gaps = 31/203 (15%)
Query: 162 VSLEGSCL-----IERKETNRKFYCQDIRAYDILFGDTPRPAQAEDLYEILDSFTEKYEN 216
++L G+C+ I E + + ++RA + + P E L ++ ++E+++
Sbjct: 66 LTLLGACVANCGKIFHLEVCSRDFATEVRA---VIKNKAHPKVCEKLKSLMVEWSEEFQK 122
Query: 217 EGQRINARKAAREQRKSSAKELPPKPLSRPQQSSAPVQLNSGSQSNRNEYKLYPGL---- 272
+ Q + A + K PP + Q SA + + S N+ + + +
Sbjct: 123 DPQ-FSLISATIKSMKEEGITFPP---AGSQTVSAAAKNGTSSNKNKEDEDIAKAIELSL 178
Query: 273 -----------SSYHERVGNLNQPI--EVTALYSFEGQQPGDLNFQAGDRITVISKTDSH 319
S Y LN + +V ALY FE + +L F+ G+ I V+ +D++
Sbjct: 179 QEQKQQHTETKSLYPSSEIQLNNKVARKVRALYDFEAVEDNELTFKHGEIIIVLDDSDAN 238
Query: 320 FDWWEGKLRGQTGIFPANYVTMN 342
WW+G+ G+FP+N+VT N
Sbjct: 239 --WWKGENHRGIGLFPSNFVTTN 259
>gi|4507247 SH3 and cysteine rich domain [Homo sapiens]
Length = 402
Score = 53.1 bits (126), Expect = 3e-07
Identities = 31/88 (35%), Positives = 47/88 (53%), Gaps = 14/88 (15%)
Query: 264 NEYKLYP--GLSSYHERVGNLNQ-------PIEVT---ALYSFEGQQPGDLNFQAGDRIT 311
N YP G + + N+N P+++ ALY F Q+ DL + GD IT
Sbjct: 254 NSVFTYPENGTDDFRDPAKNINHQGSLSKDPLQMNTYVALYKFVPQENEDLEMRPGDIIT 313
Query: 312 VISKTDSHFDWWEGKLRGQTGIFPANYV 339
++ DS+ DWW+GK++ + G FPAN+V
Sbjct: 314 LLE--DSNEDWWKGKIQDRIGFFPANFV 339
>gi|51988887 SH3 domain containing ring finger 1 [Homo sapiens]
Length = 888
Score = 53.1 bits (126), Expect = 3e-07
Identities = 31/91 (34%), Positives = 47/91 (51%), Gaps = 10/91 (10%)
Query: 249 SSAPVQLNSGSQSNRNEYKLYPGLSSYHERVGNLNQPIEVTALYSFEGQQPGDLNFQAGD 308
SS +Q + G Q P + S+ V + Q ALY++EG++PGDL F GD
Sbjct: 108 SSKDLQSSQGGQQ--------PRVQSWSPPVRGIPQLPCAKALYNYEGKEPGDLKFSKGD 159
Query: 309 RITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
I + + D +W+ G++ G G FP N+V
Sbjct: 160 IIILRRQVDE--NWYHGEVNGIHGFFPTNFV 188
Score = 37.4 bits (85), Expect = 0.020
Identities = 24/62 (38%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 285 PIEVTALYSFEGQQPGD----LNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVT 340
P + ALY FE + L F D +TVI + D + W EG L + GIFP +YV
Sbjct: 198 PPQCKALYDFEVKDKEADKDCLPFAKDDVLTVIRRVDEN--WAEGMLADKIGIFPISYVE 255
Query: 341 MN 342
N
Sbjct: 256 FN 257
Score = 30.8 bits (68), Expect = 1.8
Identities = 16/49 (32%), Positives = 28/49 (57%), Gaps = 4/49 (8%)
Query: 293 SFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLR--GQTGIFPANYV 339
S+ Q +L + GD + V K + W++G L+ G+TG+FP ++V
Sbjct: 839 SYPPQSEAELELKEGDIVFVHKKRED--GWFKGTLQRNGKTGLFPGSFV 885
>gi|4506931 SH3-domain GRB2-like 2 [Homo sapiens]
Length = 352
Score = 52.8 bits (125), Expect = 5e-07
Identities = 24/50 (48%), Positives = 33/50 (66%), Gaps = 2/50 (4%)
Query: 290 ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
ALY FE + G+L F+ GD IT+ ++ D +W+EG L G +G FP NYV
Sbjct: 297 ALYDFEPENEGELGFKEGDIITLTNQIDE--NWYEGMLHGHSGFFPINYV 344
>gi|89886447 nitric oxide synthase trafficker isoform 2 [Homo
sapiens]
Length = 506
Score = 52.4 bits (124), Expect = 6e-07
Identities = 33/112 (29%), Positives = 51/112 (45%), Gaps = 10/112 (8%)
Query: 228 REQRKSSAKELPPKPLSRPQQSSAPVQLNSGSQSNRNEYKLYPGLSSYHERVGNLNQPIE 287
RE+ + + +P + + + +SG QSN PG + R+
Sbjct: 391 REKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRL-------- 442
Query: 288 VTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
ALYSF+ +Q +LN + GD + + K + WW G L G+ G FPA YV
Sbjct: 443 CKALYSFQARQDDELNLEKGDIVIIHEKKEE--GWWFGSLNGKKGHFPAAYV 492
>gi|16418431 nitric oxide synthase trafficker isoform 1 [Homo
sapiens]
Length = 428
Score = 52.4 bits (124), Expect = 6e-07
Identities = 33/112 (29%), Positives = 51/112 (45%), Gaps = 10/112 (8%)
Query: 228 REQRKSSAKELPPKPLSRPQQSSAPVQLNSGSQSNRNEYKLYPGLSSYHERVGNLNQPIE 287
RE+ + + +P + + + +SG QSN PG + R+
Sbjct: 313 REKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRL-------- 364
Query: 288 VTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
ALYSF+ +Q +LN + GD + + K + WW G L G+ G FPA YV
Sbjct: 365 CKALYSFQARQDDELNLEKGDIVIIHEKKEE--GWWFGSLNGKKGHFPAAYV 414
>gi|166064036 PAK-interacting exchange factor beta isoform d [Homo
sapiens]
Length = 753
Score = 52.4 bits (124), Expect = 6e-07
Identities = 31/83 (37%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
Query: 258 GSQS-NRNEYKLYPGLSSYHERVGNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKT 316
GSQS + KL+ G + N N + V A ++F+ +L+F GD I V
Sbjct: 108 GSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVE 167
Query: 317 DSHFDWWEGKLRGQTGIFPANYV 339
+ WWEG L G+TG FP+NYV
Sbjct: 168 EG--GWWEGTLNGRTGWFPSNYV 188
>gi|166064034 PAK-interacting exchange factor beta isoform c [Homo
sapiens]
Length = 803
Score = 52.4 bits (124), Expect = 6e-07
Identities = 31/83 (37%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
Query: 258 GSQS-NRNEYKLYPGLSSYHERVGNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKT 316
GSQS + KL+ G + N N + V A ++F+ +L+F GD I V
Sbjct: 158 GSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVE 217
Query: 317 DSHFDWWEGKLRGQTGIFPANYV 339
+ WWEG L G+TG FP+NYV
Sbjct: 218 EG--GWWEGTLNGRTGWFPSNYV 238
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,877,790
Number of Sequences: 37866
Number of extensions: 581466
Number of successful extensions: 2088
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 137
Number of HSP's successfully gapped in prelim test: 99
Number of HSP's that attempted gapping in prelim test: 1719
Number of HSP's gapped (non-prelim): 347
length of query: 342
length of database: 18,247,518
effective HSP length: 103
effective length of query: 239
effective length of database: 14,347,320
effective search space: 3429009480
effective search space used: 3429009480
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.