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Search of human proteins with 227430303
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|227430303 CD109 antigen isoform 3 precursor [Homo sapiens]
(1368 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|227430303 CD109 antigen isoform 3 precursor [Homo sapiens] 2721 0.0
gi|115529484 CD109 antigen isoform 1 precursor [Homo sapiens] 2542 0.0
gi|227430301 CD109 antigen isoform 2 precursor [Homo sapiens] 2499 0.0
gi|74271845 alpha-2-macroglobulin-like 1 [Homo sapiens] 474 e-133
gi|66932947 alpha-2-macroglobulin precursor [Homo sapiens] 463 e-130
gi|162809334 pregnancy-zone protein [Homo sapiens] 445 e-124
gi|239744583 PREDICTED: ovostatin 2 [Homo sapiens] 364 e-100
gi|169204289 PREDICTED: ovostatin [Homo sapiens] 359 9e-99
gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain conta... 329 1e-89
gi|178557739 complement component 4B preproprotein [Homo sapiens] 239 1e-62
gi|67190748 complement component 4A preproprotein [Homo sapiens] 239 2e-62
gi|239740684 PREDICTED: similar to C4A protein isoform 1 [Homo s... 239 2e-62
gi|239740686 PREDICTED: similar to C4A protein isoform 2 [Homo s... 235 2e-61
gi|115298678 complement component 3 precursor [Homo sapiens] 224 3e-58
gi|38016947 complement component 5 preproprotein [Homo sapiens] 183 9e-46
gi|169218213 PREDICTED: similar to complement component C3, part... 180 9e-45
gi|239750255 PREDICTED: similar to ovostatin-2 [Homo sapiens] 177 5e-44
gi|239758130 PREDICTED: similar to complement component 4B (Chil... 117 6e-26
gi|169217711 PREDICTED: similar to Ovostatin homolog 2 [Homo sap... 87 8e-17
gi|239755748 PREDICTED: ovostatin [Homo sapiens] 57 9e-08
gi|169214179 PREDICTED: similar to complement component 3 [Homo ... 56 2e-07
gi|239754277 PREDICTED: similar to Complement component 4A (Rodg... 49 4e-05
gi|169217713 PREDICTED: similar to Ovostatin homolog 2 [Homo sap... 47 2e-04
gi|239752557 PREDICTED: similar to Ovostatin homolog 2 [Homo sap... 47 2e-04
gi|225735595 RNA polymerase II associated protein 3 isoform 3 [H... 35 0.64
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 35 0.64
gi|73695465 synaptic vesicle glycoprotein 2C [Homo sapiens] 33 1.9
gi|169205183 PREDICTED: similar to hCG38149 [Homo sapiens] 33 2.4
gi|239744557 PREDICTED: hypothetical protein LOC728715 [Homo sap... 33 2.4
gi|239752555 PREDICTED: similar to Ovostatin homolog 2 [Homo sap... 31 7.1
>gi|227430303 CD109 antigen isoform 3 precursor [Homo sapiens]
Length = 1368
Score = 2721 bits (7052), Expect = 0.0
Identities = 1368/1368 (100%), Positives = 1368/1368 (100%)
Query: 1 MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKA 60
MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKA
Sbjct: 1 MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKA 60
Query: 61 ELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSDPKSNLIQQWLSQQSDLGVISKTFQLSS 120
ELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSDPKSNLIQQWLSQQSDLGVISKTFQLSS
Sbjct: 61 ELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSDPKSNLIQQWLSQQSDLGVISKTFQLSS 120
Query: 121 HPILGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCSMNSKHLNGTITAKYTYG 180
HPILGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCSMNSKHLNGTITAKYTYG
Sbjct: 121 HPILGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCSMNSKHLNGTITAKYTYG 180
Query: 181 KPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEMKNVMDSSNGLSEYLDLSS 240
KPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEMKNVMDSSNGLSEYLDLSS
Sbjct: 181 KPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEMKNVMDSSNGLSEYLDLSS 240
Query: 241 PGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVLKPSLNFTATVKVTRADG 300
PGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVLKPSLNFTATVKVTRADG
Sbjct: 241 PGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVLKPSLNFTATVKVTRADG 300
Query: 301 NQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINYTVPQSGTFKIEFPILED 360
NQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINYTVPQSGTFKIEFPILED
Sbjct: 301 NQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINYTVPQSGTFKIEFPILED 360
Query: 361 SSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVGSPFELVVSGNKRLKELS 420
SSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVGSPFELVVSGNKRLKELS
Sbjct: 361 SSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVGSPFELVVSGNKRLKELS 420
Query: 421 YMVVSRGQLVAVGKQNSTMFSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKN 480
YMVVSRGQLVAVGKQNSTMFSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKN
Sbjct: 421 YMVVSRGQLVAVGKQNSTMFSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKN 480
Query: 481 KIKLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMNASNDITMENVVHELELY 540
KIKLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMNASNDITMENVVHELELY
Sbjct: 481 KIKLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMNASNDITMENVVHELELY 540
Query: 541 NTGYYLGMFMNSFAVFQECGLWVLTDANLTKDYIDGVYDNAEYAERFMEENEGHIVDIHD 600
NTGYYLGMFMNSFAVFQECGLWVLTDANLTKDYIDGVYDNAEYAERFMEENEGHIVDIHD
Sbjct: 541 NTGYYLGMFMNSFAVFQECGLWVLTDANLTKDYIDGVYDNAEYAERFMEENEGHIVDIHD 600
Query: 601 FSLGSSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTT 660
FSLGSSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTT
Sbjct: 601 FSLGSSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTT 660
Query: 661 TPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSN 720
TPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSN
Sbjct: 661 TPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSN 720
Query: 721 EINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTALSPTASDAVTQMILVKAEGIE 780
EINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTALSPTASDAVTQMILVKAEGIE
Sbjct: 721 EINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTALSPTASDAVTQMILVKAEGIE 780
Query: 781 KSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRM 840
KSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRM
Sbjct: 781 KSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRM 840
Query: 841 PYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAF 900
PYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAF
Sbjct: 841 PYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAF 900
Query: 901 GNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSE 960
GNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSE
Sbjct: 901 GNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSE 960
Query: 961 LQGGNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEFSRGISDNYTLALITYALS 1020
LQGGNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEFSRGISDNYTLALITYALS
Sbjct: 961 LQGGNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEFSRGISDNYTLALITYALS 1020
Query: 1021 SVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDSWQPRSLDIEVAAYALLSHFLQFQ 1080
SVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDSWQPRSLDIEVAAYALLSHFLQFQ
Sbjct: 1021 SVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDSWQPRSLDIEVAAYALLSHFLQFQ 1080
Query: 1081 TSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNTERTNIQVTVTGPSSPSP 1140
TSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNTERTNIQVTVTGPSSPSP
Sbjct: 1081 TSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNTERTNIQVTVTGPSSPSP 1140
Query: 1141 VKFLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQN 1200
VKFLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQN
Sbjct: 1141 VKFLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQN 1200
Query: 1201 QEAFDLDVAVKENKDDLNHVDLNVCTSFSGPGRSGMALMEVNLLSGFMVPSEAISLSETV 1260
QEAFDLDVAVKENKDDLNHVDLNVCTSFSGPGRSGMALMEVNLLSGFMVPSEAISLSETV
Sbjct: 1201 QEAFDLDVAVKENKDDLNHVDLNVCTSFSGPGRSGMALMEVNLLSGFMVPSEAISLSETV 1260
Query: 1261 KKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNS 1320
KKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNS
Sbjct: 1261 KKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNS 1320
Query: 1321 EVKLSSCDLCSDVQGCRPCEDGASGSHHHSSVIFIFCFKLLYFMELWL 1368
EVKLSSCDLCSDVQGCRPCEDGASGSHHHSSVIFIFCFKLLYFMELWL
Sbjct: 1321 EVKLSSCDLCSDVQGCRPCEDGASGSHHHSSVIFIFCFKLLYFMELWL 1368
>gi|115529484 CD109 antigen isoform 1 precursor [Homo sapiens]
Length = 1445
Score = 2542 bits (6588), Expect = 0.0
Identities = 1277/1279 (99%), Positives = 1277/1279 (99%)
Query: 90 LPSDPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVL 149
L DPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVL
Sbjct: 167 LIKDPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVL 226
Query: 150 PKFEVTLQTPLYCSMNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKI 209
PKFEVTLQTPLYCSMNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKI
Sbjct: 227 PKFEVTLQTPLYCSMNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKI 286
Query: 210 NGSANFSFNDEEMKNVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQ 269
NGSANFSFNDEEMKNVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQ
Sbjct: 287 NGSANFSFNDEEMKNVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQ 346
Query: 270 HDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSN 329
HDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSN
Sbjct: 347 HDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSN 406
Query: 330 SGNQKMEAVQKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKT 389
SGNQKMEAVQKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKT
Sbjct: 407 SGNQKMEAVQKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKT 466
Query: 390 YIQLKTRDENIKVGSPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWT 449
YIQLKTRDENIKVGSPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWT
Sbjct: 467 YIQLKTRDENIKVGSPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWT 526
Query: 450 PKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSI 509
PKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSI
Sbjct: 527 PKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSI 586
Query: 510 VGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANL 569
VGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANL
Sbjct: 587 VGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANL 646
Query: 570 TKDYIDGVYDNAEYAERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIY 629
TKDYIDGVYDNAEYAERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIY
Sbjct: 647 TKDYIDGVYDNAEYAERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIY 706
Query: 630 QEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFAL 689
QEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFAL
Sbjct: 707 QEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFAL 766
Query: 690 EITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTH 749
EITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTH
Sbjct: 767 EITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTH 826
Query: 750 LGEIPITVTALSPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPP 809
LGEIPITVTALSPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPP
Sbjct: 827 LGEIPITVTALSPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPP 886
Query: 810 NTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLT 869
NTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLT
Sbjct: 887 NTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLT 946
Query: 870 DNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDID 929
DNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDID
Sbjct: 947 DNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDID 1006
Query: 930 QNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNI 989
QNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNI
Sbjct: 1007 QNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNI 1066
Query: 990 DVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVS 1049
DVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVS
Sbjct: 1067 DVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVS 1126
Query: 1050 SESKLSDSWQPRSLDIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTV 1109
SESKLSDSWQPRSLDIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTV
Sbjct: 1127 SESKLSDSWQPRSLDIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTV 1186
Query: 1110 ALKALSEFAALMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNIS 1169
ALKALSEFAALMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNIS
Sbjct: 1187 ALKALSEFAALMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNIS 1246
Query: 1170 ANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFS 1229
ANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFS
Sbjct: 1247 ANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFS 1306
Query: 1230 GPGRSGMALMEVNLLSGFMVPSEAISLSETVKKVEYDHGKLNLYLDSVNETQFCVNIPAV 1289
GPGRSGMALMEVNLLSGFMVPSEAISLSETVKKVEYDHGKLNLYLDSVNETQFCVNIPAV
Sbjct: 1307 GPGRSGMALMEVNLLSGFMVPSEAISLSETVKKVEYDHGKLNLYLDSVNETQFCVNIPAV 1366
Query: 1290 RNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVKLSSCDLCSDVQGCRPCEDGASGSHHH 1349
RNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVKLSSCDLCSDVQGCRPCEDGASGSHHH
Sbjct: 1367 RNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVKLSSCDLCSDVQGCRPCEDGASGSHHH 1426
Query: 1350 SSVIFIFCFKLLYFMELWL 1368
SSVIFIFCFKLLYFMELWL
Sbjct: 1427 SSVIFIFCFKLLYFMELWL 1445
Score = 184 bits (468), Expect = 4e-46
Identities = 93/94 (98%), Positives = 93/94 (98%)
Query: 1 MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKA 60
MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKA
Sbjct: 1 MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKA 60
Query: 61 ELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSDP 94
ELLKTASNLTVSVLEAEGVFEKGSFKTLTLPS P
Sbjct: 61 ELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLP 94
>gi|227430301 CD109 antigen isoform 2 precursor [Homo sapiens]
Length = 1428
Score = 2499 bits (6476), Expect = 0.0
Identities = 1260/1279 (98%), Positives = 1260/1279 (98%), Gaps = 17/1279 (1%)
Query: 90 LPSDPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVL 149
L DPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVL
Sbjct: 167 LIKDPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVL 226
Query: 150 PKFEVTLQTPLYCSMNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKI 209
PKFEVTLQTPLYCSMNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKI
Sbjct: 227 PKFEVTLQTPLYCSMNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKI 286
Query: 210 NGSANFSFNDEEMKNVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQ 269
NGSANFSFNDEEMKNVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQ
Sbjct: 287 NGSANFSFNDEEMKNVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQ 346
Query: 270 HDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSN 329
HDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSN
Sbjct: 347 HDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSN 406
Query: 330 SGNQKMEAVQKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKT 389
SGNQKMEAVQKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKT
Sbjct: 407 SGNQKMEAVQKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKT 466
Query: 390 YIQLKTRDENIKVGSPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWT 449
YIQLKTRDENIKVGSPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWT
Sbjct: 467 YIQLKTRDENIKVGSPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWT 526
Query: 450 PKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSI 509
PKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSI
Sbjct: 527 PKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSI 586
Query: 510 VGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANL 569
VGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANL
Sbjct: 587 VGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANL 646
Query: 570 TKDYIDGVYDNAEYAERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIY 629
TKDYIDGVYDNAEYAERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIY
Sbjct: 647 TKDYIDGVYDNAEYAERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIY 706
Query: 630 QEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFAL 689
QEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFAL
Sbjct: 707 QEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFAL 766
Query: 690 EITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTH 749
EITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTH
Sbjct: 767 EITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTH 826
Query: 750 LGEIPITVTALSPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPP 809
LGEIPITVTALSPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPP
Sbjct: 827 LGEIPITVTALSPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPP 886
Query: 810 NTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLT 869
NTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLT
Sbjct: 887 NTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLT 946
Query: 870 DNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDID 929
DNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDID
Sbjct: 947 DNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDID 1006
Query: 930 QNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNI 989
QNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNI
Sbjct: 1007 QNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNI 1066
Query: 990 DVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVS 1049
DVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVS
Sbjct: 1067 DVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVS 1126
Query: 1050 SESKLSDSWQPRSLDIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTV 1109
SESKLSDSWQPRSLDIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTV
Sbjct: 1127 SESKLSDSWQPRSLDIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTV 1186
Query: 1110 ALKALSEFAALMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNIS 1169
ALKALSEFAALMNTERTNIQVTVTGPSSPSP LAVVQPTAVNIS
Sbjct: 1187 ALKALSEFAALMNTERTNIQVTVTGPSSPSP-----------------LAVVQPTAVNIS 1229
Query: 1170 ANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFS 1229
ANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFS
Sbjct: 1230 ANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFS 1289
Query: 1230 GPGRSGMALMEVNLLSGFMVPSEAISLSETVKKVEYDHGKLNLYLDSVNETQFCVNIPAV 1289
GPGRSGMALMEVNLLSGFMVPSEAISLSETVKKVEYDHGKLNLYLDSVNETQFCVNIPAV
Sbjct: 1290 GPGRSGMALMEVNLLSGFMVPSEAISLSETVKKVEYDHGKLNLYLDSVNETQFCVNIPAV 1349
Query: 1290 RNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVKLSSCDLCSDVQGCRPCEDGASGSHHH 1349
RNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVKLSSCDLCSDVQGCRPCEDGASGSHHH
Sbjct: 1350 RNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVKLSSCDLCSDVQGCRPCEDGASGSHHH 1409
Query: 1350 SSVIFIFCFKLLYFMELWL 1368
SSVIFIFCFKLLYFMELWL
Sbjct: 1410 SSVIFIFCFKLLYFMELWL 1428
Score = 184 bits (468), Expect = 4e-46
Identities = 93/94 (98%), Positives = 93/94 (98%)
Query: 1 MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKA 60
MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKA
Sbjct: 1 MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKA 60
Query: 61 ELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSDP 94
ELLKTASNLTVSVLEAEGVFEKGSFKTLTLPS P
Sbjct: 61 ELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLP 94
>gi|74271845 alpha-2-macroglobulin-like 1 [Homo sapiens]
Length = 1454
Score = 474 bits (1221), Expect = e-133
Identities = 377/1345 (28%), Positives = 637/1345 (47%), Gaps = 174/1345 (12%)
Query: 93 DPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVLPKF 152
DP SN I QWL + G++ +FQL+ +LG +++ V + + +F V EYVLPKF
Sbjct: 162 DPNSNRIAQWLEVVPEQGIVDLSFQLAPEAMLGTYTVAVA--EGKTFGTFSVEEYVLPKF 219
Query: 153 EVTLQTPLYCSMNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGS 212
+V + P S + I +YTYGKP+ G V ++ +K T ++
Sbjct: 220 KVEVVEPKELSTVQESFLVKICCRYTYGKPMLGAVQVSVC-------QKANTYWYREVER 272
Query: 213 ANFSFNDEEMKNVMDSSNGLSEYLDLSS--------PGPVEILTTVTESVTGISRNVSTN 264
+ D + S +D+++ + I+ TV E TG+ N + N
Sbjct: 273 EQLPDKCRNLSGQTDKTGCFSAPVDMATFDLIGYAYSHQINIVATVVEEGTGVEANATQN 332
Query: 265 VFFKQHDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITV---TQRNY 321
++ + F D + P+ F+ ++V D + L +N++V V T +
Sbjct: 333 IYISPQMGSMTFEDTSNFYHPNFPFSGKIRVRGHDDSFL-----KNHLVFLVIYGTNGTF 387
Query: 322 TEYWSGSNSGNQK--MEAVQKINYTVPQSGTFKIE--------FPILEDSSELQLKAYFL 371
+ N+G +E V G F++E P ++ L L+ ++
Sbjct: 388 NQTLVTDNNGLAPFTLETSGWNGTDVSLEGKFQMEDLVYNPEQVPRYYQNAYLHLRPFYS 447
Query: 372 GSKSSMAVHSLFKSPSKTYIQLKTRDENIKVGSPFELVV---------SGNKRLKELSYM 422
++S + +H L + +K G P E++V S ++ + SY
Sbjct: 448 TTRSFLGIHRL--------------NGPLKCGQPQEVLVDYYIDPADASPDQEIS-FSYY 492
Query: 423 VVSRGQLVAVGKQN----------STMFSLTPENSWTPKACVIVYYIEDDGEIISDVLKI 472
++ +G LV G+++ S SLT + P +++Y I G +++D ++
Sbjct: 493 LIGKGSLVMEGQKHLNSKKKGLKASFSLSLTFTSRLAPDPSLVIYAIFPSGGVVADKIQF 552
Query: 473 PVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMNASNDITMEN 532
V++ F N++ L +S + P +V L++ P S+ + AVD+SV L+ +++ +
Sbjct: 553 SVEMCFDNQVSLGFSPSQQLPGAEVELQLQAA-PGSLCALRAVDESVLLLRPDRELSNRS 611
Query: 533 VV-----------HELELYNTGYYLGMF-----------------------------MNS 552
V +++ Y+ G + +
Sbjct: 612 VYGMFPFWYGHYPYQVAEYDQCPVSGPWDFPQPLIDPMPQGHSSQRSIIWRPSFSEGTDL 671
Query: 553 FAVFQECGLWVLTDANLTKDYIDGVYDNAEYAERFMEENEGHIVDIHDFS---LGSSPHV 609
F+ F++ GL +L++A + K +D + + EY+ M GH + V
Sbjct: 672 FSFFRDVGLKILSNAKIKKP-VDCSHRSPEYSTA-MGAGGGHPEAFESSTPLHQAEDSQV 729
Query: 610 RKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQ 669
R++FPETW+W +G + VTVPD+IT W A F S+ G GL+ T V L AF+
Sbjct: 730 RQYFPETWLWDLFPIGNSGKEAVHVTVPDAITEWKAMSFCTSQSRGFGLSPT-VGLTAFK 788
Query: 670 PFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQ 729
PFF+ L LPYSV+RGE F L TIFNYLKD V+ + KS ++ + ++ Q
Sbjct: 789 PFFVDLTLPYSVVRGESFRLTATIFNYLKDCIRVQTDLAKSHEYQLESWADS------QT 842
Query: 730 TLLVPSEDGATVLFPIRPTHLGEIPITVTAL----------------SPTASDAVTQMIL 773
+ + +++ T + I LG I T++ SD + + +L
Sbjct: 843 SSCLCADEAKTHHWNITAVKLGHINFTISTKILDSNEPCGGQKGFVPQKGRSDTLIKPVL 902
Query: 774 VKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAIGDVLGPSING 833
VK EG+ + S LL ++ S +++S P + V S + +T +GD++G ++
Sbjct: 903 VKPEGVLVEKTHSSLL-CPKGKVAS--ESVSLELPVDIVPDSTKAYVTVLGDIMGTALQN 959
Query: 834 LASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQRE 893
L L++MP GCGEQNM+ FAP IY+L YL K LT+ ++ +A+ F+ GYQ+EL+Y+
Sbjct: 960 LDGLVQMPSGCGEQNMVLFAPIIYVLQYLEKAGLLTEEIRSRAVGFLEIGYQKELMYKHS 1019
Query: 894 DGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDP 953
+GS+SAFG D +G+TWL+AFV +CF +A +I ID + W+ G+Q +G + +
Sbjct: 1020 NGSYSAFGERDGNGNTWLTAFVTKCFGQAQKFIFIDPKNIQDALKWMAGNQLPSGCYANV 1079
Query: 954 GRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEFSRGISDNYTLA 1013
G ++H+ ++GG V+LTAY+ +LL K + V + + L++ + ++ YT A
Sbjct: 1080 GNLLHTAMKGGVDDEVSLTAYVTAALLEMGKDVDDPMVSQGLRCLKNS-ATSTTNLYTQA 1138
Query: 1014 LITYALSSVGSPKAKE-ALNMLTWRAEQEGGMQFWVSSESKLSDS--W-QPRSLDIEVAA 1069
L+ Y S G + L L +A G +W + S++ W +P ++D+E+ A
Sbjct: 1139 LLAYIFSLAGEMDIRNILLKQLDQQAIISGESIYWSQKPTPSSNASPWSEPAAVDVELTA 1198
Query: 1070 YALLSH-----FLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFA--ALMN 1122
YALL+ Q + ++ I+ WL++QRN+ GGF+STQDT VAL+AL+++A A M
Sbjct: 1199 YALLAQLTKPSLTQKEIAKATSIVAWLAKQRNAYGGFSSTQDTVVALQALAKYATTAYMP 1258
Query: 1123 TERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNV 1182
+E N+ V T + F I + NRL+ Q L V P + A+G G Q +
Sbjct: 1259 SEEINLVVKSTENFQRT---FNIQSVNRLVFQQDTLPNV-PGMYTLEASGQGCVYVQTVL 1314
Query: 1183 VYNVKASGSSRRRRSIQNQEAFDLDVAVK----ENKDDLNHVDLNVCTSFSGP-GRSGMA 1237
YN+ N + F L V + E + L + TS+ G S MA
Sbjct: 1315 RYNILPP---------TNMKTFSLSVEIGKARCEQPTSPRSLTLTIHTSYVGSRSSSNMA 1365
Query: 1238 LMEVNLLSGF--MVPSEAISLSE-TVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKV 1294
++EV +LSGF M + + L + VKKVE+ LN+YLD + + ++ V
Sbjct: 1366 IVEVKMLSGFSPMEGTNQLLLQQPLVKKVEFGTDTLNIYLDELIKNTQTYTFTISQSVLV 1425
Query: 1295 SNTQDASVSIVDYYEPRRQAVRSYN 1319
+N + A++ + DYY P QA Y+
Sbjct: 1426 TNLKPATIKVYDYYLPDEQATIQYS 1450
>gi|66932947 alpha-2-macroglobulin precursor [Homo sapiens]
Length = 1474
Score = 463 bits (1191), Expect = e-130
Identities = 387/1347 (28%), Positives = 630/1347 (46%), Gaps = 169/1347 (12%)
Query: 93 DPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQS-FQVSEYVLPK 151
DPK N I QW S Q + G+ +F LSS P G + + VQ + F V E+VLPK
Sbjct: 169 DPKGNRIAQWQSFQLEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPK 228
Query: 152 FEVTLQTPLYCSMNSKHLNGTITAKYTYGKPVKGDVTLT----FLPLSFWGKKKNITKTF 207
FEV + P ++ + +N ++ YTYGKPV G VT++ + S + +
Sbjct: 229 FEVQVTVPKIITILEEEMNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCE 288
Query: 208 KINGSANFS--FNDEEMKNVMDSSNGLSEY-LDLSSPGPVEILTTVTESVTGISRNVSTN 264
K +G N F + V EY + L + ++ TV E +TG + T
Sbjct: 289 KFSGQLNSHGCFYQQVKTKVFQLKR--KEYEMKLHTEAQIQEEGTVVE-LTGRQSSEITR 345
Query: 265 VFFKQHDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEY 324
K + F + + + F V++ G + N VI + + N Y
Sbjct: 346 TITK-----LSFVKVDSHFRQGIPFFGQVRLVDGKGVPIP------NKVIFI-RGNEANY 393
Query: 325 WSGSNSGNQKMEAVQKINYT--VPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSL 382
+S + + + IN T + S T ++ + Q ++ + A H+
Sbjct: 394 YSNATTDEHGLVQFS-INTTNVMGTSLTVRVNYKDRSPCYGYQ----WVSEEHEEAHHTA 448
Query: 383 FK--SPSKTYIQLKTRDENIKVGSPFEL----VVSGNKRL--KELS--YMVVSRGQLVAV 432
+ SPSK+++ L+ + G + +++G L K+LS Y+++++G +V
Sbjct: 449 YLVFSPSKSFVHLEPMSHELPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRT 508
Query: 433 GKQNSTM----------FSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKI 482
G + S+ ++ P A +++Y + G++I D K V+ NK+
Sbjct: 509 GTHGLLVKQEDMKGHFSISIPVKSDIAPVARLLIYAVLPTGDVIGDSAKYDVENCLANKV 568
Query: 483 KLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMNASNDITMENVVHELELYNT 542
L +S ++ P+ LR++ P S+ + AVD+SV LM +++ +V + L +
Sbjct: 569 DLSFSPSQSLPASHAHLRVTAA-PQSVCALRAVDQSVLLMKPDAELSASSVYNLLPEKDL 627
Query: 543 GYYLG---------------MFMNS--------------FAVFQECGLWVLTDANLTKDY 573
+ G +++N ++ ++ GL T++ + K
Sbjct: 628 TGFPGPLNDQDDEDCINRHNVYINGITYTPVSSTNEKDMYSFLEDMGLKAFTNSKIRKPK 687
Query: 574 IDGVYDNAE-----------YAERFMEENEGHIVDIHDFSLGSSPH---VRKHFPETWIW 619
+ E Y M +V + + PH VRK+FPETWIW
Sbjct: 688 MCPQLQQYEMHGPEGLRVGFYESDVMGRGHARLVHVEE------PHTETVRKYFPETWIW 741
Query: 620 LDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPY 679
+ E VTVPD+IT W A F +SED GLG+++T L+AFQPFF+ L +PY
Sbjct: 742 DLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISST-ASLRAFQPFFVELTMPY 800
Query: 680 SVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGA 739
SVIRGE F L+ T+ NYL V V +E S F + E Q + +
Sbjct: 801 SVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVEKE------QAPHCICANGRQ 854
Query: 740 TVLFPIRPTHLGEIPITVTALSPTAS----------------DAVTQMILVKAEGIEKSY 783
TV + + P LG + TV+A + + D V + +LV+ EG+EK
Sbjct: 855 TVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVIKPLLVEPEGLEKET 914
Query: 784 SQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYG 843
+ + LL + + + LS PPN V S R ++ +GD+LG ++ +L++MPYG
Sbjct: 915 TFNSLLCPSGGEVS---EELSLKLPPNVVEESARASVSVLGDILGSAMQNTQNLLQMPYG 971
Query: 844 CGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNY 903
CGEQNM+ FAPNIY+LDYL + +QLT +K KA+ ++ GYQR+L Y+ DGS+S FG
Sbjct: 972 CGEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLNTGYQRQLNYKHYDGSYSTFGER 1031
Query: 904 --DPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSEL 961
G+TWL+AFVL+ F +A YI ID+ + + WL QK NG F G ++++ +
Sbjct: 1032 YGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLSQRQKDNGCFRSSGSLLNNAI 1091
Query: 962 QGGNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEFSRGI-----SDNYTLALIT 1016
+GG + VTL+AYI +LL + V+ ++ LES + S YT AL+
Sbjct: 1092 KGGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESAWKTAQEGDHGSHVYTKALLA 1151
Query: 1017 YALSSVGS-PKAKEALNMLTWRAEQEGGMQFW---VSSESKLSDSWQPR--SLDIEVAAY 1070
YA + G+ K KE L L A ++ W ++ + ++P+ S ++E+ +Y
Sbjct: 1152 YAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKPKAPVGHFYEPQAPSAEVEMTSY 1211
Query: 1071 ALLSHFL--QFQTSEGIP----IMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNTE 1124
LL++ TSE + I++W+++Q+N+ GGF+STQDT VAL ALS++ A T
Sbjct: 1212 VLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFT- 1270
Query: 1125 RTNIQVTVTGPSSPS-PVKFLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVV 1183
RT VT SS + KF +D +NRLLLQ L + P ++ G G Q ++
Sbjct: 1271 RTGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPEL-PGEYSMKVTGEGCVYLQTSLK 1329
Query: 1184 YNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLN----HVDLNVCTSFSGPG---RSGM 1236
YN+ + +E F + V+ + H + S S G S M
Sbjct: 1330 YNI-----------LPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNM 1378
Query: 1237 ALMEVNLLSGFMVPSEAISL---SETVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFK 1293
A+++V ++SGF+ + + S V + E + +YLD V+ + +++
Sbjct: 1379 AIVDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVP 1438
Query: 1294 VSNTQDASVSIVDYYEPRRQAVRSYNS 1320
V + + A V + DYYE A+ YN+
Sbjct: 1439 VRDLKPAIVKVYDYYETDEFAIAEYNA 1465
>gi|162809334 pregnancy-zone protein [Homo sapiens]
Length = 1482
Score = 445 bits (1145), Expect = e-124
Identities = 378/1343 (28%), Positives = 619/1343 (46%), Gaps = 158/1343 (11%)
Query: 93 DPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQS-FQVSEYVLPK 151
+P+ N I QW S + + G+ +F LSS PI G + + VQ Q F V E+VLPK
Sbjct: 168 NPRRNRIAQWQSLKLEAGINQLSFPLSSEPIQGSYRVVVQTESGGRIQHPFTVEEFVLPK 227
Query: 152 FEVTLQTPLYCSMNSKHLNGTITAKYTYGKPVKGDVTLTF---LPLSFWGKKKNITKTFK 208
FEV +Q P S+ + +N T+ +YTYGKPV G T++ L K+ + + F
Sbjct: 228 FEVKVQVPKIISIMDEKVNITVCGEYTYGKPVPGLATVSLCRKLSRVLNCDKQEVCEEFS 287
Query: 209 INGSANFSFNDEEMKNVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFK 268
++N + ++ +N E + L + T E VT + TN+ K
Sbjct: 288 QQLNSNGCITQQVHTKMLQITNTGFE-MKLRVEARIREEGTDLE-VTANRISEITNIVSK 345
Query: 269 QHDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGS 328
++F + + + F A V + DG + + + + + N Y+S +
Sbjct: 346 -----LKFVKVDSHFRQGIPFFAQVLLV--DGKGVPIPNKLFFISV-----NDANYYSNA 393
Query: 329 NSGNQKMEAVQKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFK--SP 386
+ Q + A IN T K+ + L ++ A H+ + S
Sbjct: 394 TTNEQGL-AQFSINTT--SISVNKLFVRVFTVHPNLCFHYSWVAEDHQGAQHTANRVFSL 450
Query: 387 SKTYIQLKTRDENIKVG------SPFELVVSGNKRLKELS--YMVVSRGQLVAVGK---- 434
S +YI L+ + G + + L L ELS Y+++++G +V G
Sbjct: 451 SGSYIHLEPVAGTLPCGHTETITAHYTLNRQAMGELSELSFHYLIMAKGVIVRSGTHTLP 510
Query: 435 ------QNSTMFSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSK 488
+ S S E+ P A + ++ I DGE++ D K ++ NK+ L +S
Sbjct: 511 VESGDMKGSFALSFPVESDVAPIARMFIFAILPDGEVVGDSEKFEIENCLANKVDLSFSP 570
Query: 489 VKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMNASNDITMENVVHELE---------- 538
++ P+ L+++ P S+ + AVD+SV LM ++++ +V + L
Sbjct: 571 AQSPPASHAHLQVAAA-PQSLCALRAVDQSVLLMKPEAELSVSSVYNLLTVKDLTNFPDN 629
Query: 539 ----------------LYNTGYYLGMFMNS---FAVFQECGLWVLTDANLTK-------- 571
++N Y+ + N ++ + GL V T++ + K
Sbjct: 630 VDQQEEEQGHCPRPFFIHNGAIYVPLSSNEADIYSFLKGMGLKVFTNSKIRKPKSCSVIP 689
Query: 572 DYIDGVYDNAEYAERFMEENEGHIVDIHDFSL---------GSSPH-VRKHFPETWIWLD 621
G Y ++ + +++ G P VR +FPETWIW
Sbjct: 690 SVSAGAVGQGYYGAGLGVVERPYVPQLGTYNVIPLNNEQSSGPVPETVRSYFPETWIWEL 749
Query: 622 TNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSV 681
+ E VTVPD+IT W A F +SED GLG+++T L+AFQPFF+ L +PYSV
Sbjct: 750 VAVNSSGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISST-ASLRAFQPFFVELTMPYSV 808
Query: 682 IRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATV 741
IRGE F L+ T+ NYL V V ++ S F L + N T +++ + + T+
Sbjct: 809 IRGEVFTLKATVLNYLPKCIRVSVQLKASPAF--LASQN----TKGEESYCICGNERQTL 862
Query: 742 LFPIRPTHLGEIPITVTALSPTA----------------SDAVTQMILVKAEGIEKSYSQ 785
+ + P LG + +V+A + + D V + +LV+AEGIE+ +
Sbjct: 863 SWTVTPKTLGNVNFSVSAEAMQSLELCGNEVVEVPEIKRKDTVIKTLLVEAEGIEQEKTF 922
Query: 786 SILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCG 845
S +T + + LS P N V S R + +GD+LG ++ + +L++MPYGCG
Sbjct: 923 S---SMTCASGANVSEQLSLKLPSNVVKESARASFSVLGDILGSAMQNIQNLLQMPYGCG 979
Query: 846 EQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNY-- 903
EQNM+ FAPNIY+L+YL + +QLT +K KA+ ++ GYQR+L Y+ +DGS+S FG
Sbjct: 980 EQNMVLFAPNIYVLNYLNETQQLTQEIKAKAVGYLITGYQRQLNYKHQDGSYSTFGERYG 1039
Query: 904 DPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQG 963
G+TWL+AFVL+ F +A YI ID+ + ++ TWL QK NG F G ++++ ++G
Sbjct: 1040 RNQGNTWLTAFVLKTFAQARSYIFIDEAHITQSLTWLSQMQKDNGCFRSSGSLLNNAIKG 1099
Query: 964 GNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIHFLES------EFSRGISDNYTLALITY 1017
G + TL+AY+ +LL N V+ ++ LES E + G S YT AL+ Y
Sbjct: 1100 GVEDEATLSAYVTIALLEIPLPVTNPIVRNALFCLESAWNVAKEGTHG-SHVYTKALLAY 1158
Query: 1018 ALSSVGSP-KAKEALNMLTWRAEQEGGMQFWVSSESKLSD-----SWQPRSLDIEVAAYA 1071
A S +G + +E LN L A +E + W + + Q S ++E+ +Y
Sbjct: 1159 AFSLLGKQNQNREILNSLDKEAVKEDNLVHWERPQRPKAPVGHLYQTQAPSAEVEMTSYV 1218
Query: 1072 LLSHF------LQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEF--AALMNT 1123
LL++ + I++W+ +Q+N+ GGF+STQDT VAL ALS + A T
Sbjct: 1219 LLAYLTAQPAPTSGDLTSATNIVKWIMKQQNAQGGFSSTQDTVVALHALSRYGAATFTRT 1278
Query: 1124 ERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVV 1183
E+T QVTV S F +D +N LLLQ L + P I+ G Q ++
Sbjct: 1279 EKT-AQVTVQ-DSQTFSTNFQVDNNNLLLLQQISLPEL-PGEYVITVTGERCVYLQTSMK 1335
Query: 1184 YNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLN--HVDLNVCTSFSGPGR---SGMAL 1238
YN+ + F L V D + H + + S G S M +
Sbjct: 1336 YNILPE---------KEDSPFALKVQTVPQTCDGHKAHTSFQISLTISYTGNRPASNMVI 1386
Query: 1239 MEVNLLSGFMVPSEAISL---SETVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVS 1295
++V ++SGF+ + + S +V + E + + +Y++ V + +++ V
Sbjct: 1387 VDVKMVSGFIPLKPTVKMLERSSSVSRTEVSNNHVLIYVEQVTNQTLSFSFMVLQDIPVG 1446
Query: 1296 NTQDASVSIVDYYEPRRQAVRSY 1318
+ + A V + DYYE V Y
Sbjct: 1447 DLKPAIVKVYDYYETDESVVAEY 1469
>gi|239744583 PREDICTED: ovostatin 2 [Homo sapiens]
Length = 1394
Score = 364 bits (935), Expect = e-100
Identities = 346/1315 (26%), Positives = 577/1315 (43%), Gaps = 187/1315 (14%)
Query: 87 TLTLPS----DPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQ-TYYQS 141
T T P+ DP++N I QW + S + +FQL S P+ GD+ I V+ N + T
Sbjct: 138 TFTYPNITLKDPQNNRIFQWQNVTSFRNITQLSFQLISEPMFGDYWIVVKRNSRKTVTHQ 197
Query: 142 FQVSEYVLPKFEVTLQTPLYCSMNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKK 201
F V YVLPKFEVT+ P +++ + AKYT+G+PV+G K
Sbjct: 198 FAVKRYVLPKFEVTVNAPQTVTISDDEFQVDVCAKYTFGQPVQG--------------KT 243
Query: 202 NITKTFKINGSANFSFNDEEM--KNVMDSSNGL------SEYLDLSSPG---PVEILTTV 250
I + S+N ND E+ + + NG ++ L G + V
Sbjct: 244 QIRVCREYFSSSNCEKNDNEICEQFIAQLENGCVSQIVNTKVFQLYRSGLFMTFHVAVIV 303
Query: 251 TESVTG---ISRNVSTNVFFKQHDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEE 307
TE TG + + T+VF Q + F + T + +++ T+K + D N + +
Sbjct: 304 TEFGTGNYCMQISEKTSVFITQLLGTVNFENMDTFYRRGISYFGTLKFS--DPNNVPMVN 361
Query: 308 RRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINYTVPQSGTFKIEFPILEDSSELQLK 367
+ + Q + + G+ + ++ EA +++ S F EF + ++ ++ K
Sbjct: 362 K-------LLQLELNDEFIGNYTTDENGEA----QFSIDTSDIFDPEFNL--KATYVRPK 408
Query: 368 AYFLGS---KSSMAVHSLF-KSPSKTYIQLKTRDENIKVGSPFELVVSGNKRLKELSYMV 423
+ +L S + H L + S+T LK E ++ + VV+ + L +Y
Sbjct: 409 SCYLPSWLTPQYLDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYED 468
Query: 424 VSRGQ---LVAVGKQNSTM------------------FSLTPENSWTPKACVIVYYIEDD 462
S + LV++ + F L+ P A + VY +
Sbjct: 469 DSNVKFFYLVSLSHDSGNFQHRISSSPIYTAWNGNFSFPLSISADLAPAAVLFVYTLHPS 528
Query: 463 GEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLM 522
GEI++D ++ V FK+K+ + +S + P SL + P + AVD +V L+
Sbjct: 529 GEIVADSVRFQVDKCFKHKVNIKFSNEQGLPGSNASLYLQAA-PVLFCALGAVDGNVLLL 587
Query: 523 NASNDITME---NVVHELELYNTGYY---------------LGMFMNS------------ 552
+ ++ E N+V +E Y Y+ MF N
Sbjct: 588 KSEQQLSAESVYNMVPSIEPYGYFYHGLNLDDGKEDPCIPQRDMFYNGLYYTPVSNYGDG 647
Query: 553 --FAVFQECGLWVLTDANLTKDYIDGVYDNAEYAERFMEENEG----HIVDIHDFSLGSS 606
+ + + GL V T+ + K + + + E E H V G +
Sbjct: 648 DIYNIVRNMGLKVFTNLHYRKPEVCVMERRLPLPKPLYLETENYGPMHSVPSRIACRGEN 707
Query: 607 PH---------VRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLG 657
VR +FPETW+W ++ +PD+IT W A+GF ++ D+G G
Sbjct: 708 ADYVEQAIIQTVRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFG 767
Query: 658 LTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILM 717
+++T L+ QPFFI + P+SV++ E+F L + F+YL E+ V +E+S ++ +
Sbjct: 768 ISSTTT-LEVSQPFFIEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVEESQNYEANI 826
Query: 718 TSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTALSPTAS------------ 765
+ +IN + ++ + T ++ I P LG++ ITV A S +S
Sbjct: 827 NTWKINGSE-----VIQAGGRKTNIWTIIPKKLGKVNITVVAESKQSSACPNEGMEQQKL 881
Query: 766 ---DAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITA 822
D V + LV+ EGIEK +QS L+ T+ S L P + V GS R T
Sbjct: 882 NWKDTVVKSFLVEPEGIEKERTQSFLI-CTEGAKASKQGVLDL--PNDVVEGSARGFFTV 938
Query: 823 IGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQ 882
+GD+LG ++ L +++MPYG GEQN A + Y+LDYL +QLT+ ++ KA +
Sbjct: 939 VGDILGLAMQNLV-VLQMPYGGGEQNAALLASDTYVLDYLKSTEQLTEEVQSKAFFLLSN 997
Query: 883 GYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKG 942
GYQR+L ++ DGS+S F + GS WLSA + ++ ID+NV +T WL
Sbjct: 998 GYQRQLSFKNSDGSYSVFWQQNQKGSIWLSALTFKTLERMKKFVFIDENVQKQTLIWLSS 1057
Query: 943 HQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEF 1002
QK++G F + G++ + +GG++ ++LTAY+V ++ ++ LE+
Sbjct: 1058 QQKTSGCFKNDGQLFNHAWEGGDEEDISLTAYVVGMFFEAGLNSTFPALRNALFCLEAAL 1117
Query: 1003 SRGISDNYTLALITYALSSVGSPKAKEA-LNMLTWRAEQEGGMQFWVSSESKLSDS---- 1057
G+++ Y A++ YA + G K E+ L L A + + +W ++
Sbjct: 1118 DSGVTNGYNHAILAYAFALAGKEKQVESLLQTLDQSATKLNNVIYWERERKPKTEEFPSF 1177
Query: 1058 --WQPRSLDIEVAAYALLSHFLQFQTSEGIP-------IMRWLSRQRNSLGGFASTQDTT 1108
W P S E + Y LL+ S IP I++WL++Q NS GGF+S Q
Sbjct: 1178 IPWAP-SAQTEKSCYVLLA-----VISRKIPDLTYASKIVQWLAQQMNSHGGFSSNQVIN 1231
Query: 1109 VALKALSEFAALMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNI 1168
V L ++ + VT + S S ++F + HNRLL+Q +E+ P +
Sbjct: 1232 VGLILIAICGEEGLFSKNQNTVTFSSEGS-SEIQF--NGHNRLLVQRSEVTQA-PGQYTV 1287
Query: 1169 SANGFGFAICQLNVVYNV----KASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNV 1224
G G Q + YNV KASG F L + + +N L DL V
Sbjct: 1288 DVEGRGCTFIQATLKYNVLLPKKASG-------------FSLSLEIVKNY-SLTVFDLTV 1333
Query: 1225 CTSFSG-PGRSGMALMEVNLLSGFMVPSEAISLSETVKKVEYDHGKLNLYLDSVN 1278
++G +S M +++V +LSGF +I + + Y D +N
Sbjct: 1334 NLKYTGIRNKSSMVVIDVKMLSGFTPTMSSIEEVNNRSLIFHHKDSYIEYKDKIN 1388
>gi|169204289 PREDICTED: ovostatin [Homo sapiens]
Length = 1353
Score = 359 bits (922), Expect = 9e-99
Identities = 340/1282 (26%), Positives = 564/1282 (43%), Gaps = 192/1282 (14%)
Query: 87 TLTLPS----DPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVND-QTYYQS 141
T T P+ DP++N I Q + S + +FQL S P+ GD+ I V+ N +T
Sbjct: 89 TFTYPNITLKDPQNNRIFQRQNVTSFRNITQLSFQLISEPMFGDYWIVVKRNSRETVTHQ 148
Query: 142 FQVSEYVLPKFEVTLQTPLYCSMNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKK 201
F V YVLPKFEVT+ P +++ + AKY +G+PV+G+ + F
Sbjct: 149 FAVKRYVLPKFEVTVNAPQTVTISDDEFQVDVCAKYNFGQPVQGETQIRVCREYF----- 203
Query: 202 NITKTFKINGSANFSFNDEEM--KNVMDSSNGL------SEYLDLSSPG---PVEILTTV 250
S+N N+ E+ + + NG ++ L G + V
Sbjct: 204 ---------SSSNCEKNENEICEQFIAQLENGCVSQIVNTKVFQLYRSGLFMTFHVAVIV 254
Query: 251 TESVTG---ISRNVSTNVFFKQHDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEE 307
TES TG + + T+VF Q + F + T + +++ T+K + D N + +
Sbjct: 255 TESGTGNYFMQISEKTSVFITQLLGTVNFENMDTFYRRGISYFGTLKFS--DPNNVPMVN 312
Query: 308 RRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINYTVPQSGTFKIEFP-----ILEDSS 362
+ + Q + + G+ + ++ EA +++ S F EF + +S
Sbjct: 313 K-------LLQLELNDEFIGNYTTDENGEA----QFSIDTSDIFDPEFNLKATYVRPESC 361
Query: 363 ELQ-------LKAYFLGSKSSMAVHSLFKS-PSKTYIQLKTR----------------DE 398
L L A+FL S+ +S K P ++ + D
Sbjct: 362 YLPSWLTPQYLDAHFLVSRFYSRTNSFLKIVPEPKQLECNQQKVVTVHYSLNSEAYEDDS 421
Query: 399 NIKVGSPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWTPKACVIVYY 458
N+K F +VS + + + S A S S++ + + P A + VY
Sbjct: 422 NVK----FFYLVSLSHDSGNFQHRISSSPIYTAWNGNFSFPISISADLA--PAAVLFVYT 475
Query: 459 IEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKS 518
+ GEI++D ++ V FK+K+ + +S + P SL + P + AVD++
Sbjct: 476 LHPSGEIVADSVRFQVDKCFKHKVNIKFSNEQGLPGSNASLCLQAA-PVLFCALRAVDRN 534
Query: 519 VNLMNASNDITME---NVVHELELYNTGYY---------------LGMFMNS-------- 552
V L+ + ++ E N+V +E Y Y+ MF N
Sbjct: 535 VLLLKSEQQLSAESVYNMVPSIEPYGYFYHGLNLDDGKEDPCIPQRDMFYNGLYYTPVSN 594
Query: 553 ------FAVFQECGLWVLTDANLTKDYIDGVYDNAEYAERFMEENE-------------- 592
+ + + GL V T+ + K + + + E E
Sbjct: 595 YGDGDIYNIVRNMGLKVFTNLHYRKPEVCVMERRLPLPKPLYLETENYGPMRSVPSRIAC 654
Query: 593 -GHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVIS 651
G D + ++ + VR +FPETW+W ++ +PD+IT W A+GF ++
Sbjct: 655 RGENADYVEQAIIQT--VRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVN 712
Query: 652 EDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSD 711
D+G G+++T L+ QPFFI + P+SV++ E+F L + +F+Y E+ V +E+S
Sbjct: 713 GDVGFGISSTTT-LEVSQPFFIEIASPFSVVQNEQFDLIVNVFSYRNTCVEISVQVEESQ 771
Query: 712 KFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTALSPTAS------ 765
++ + + +IN + ++ + T ++ I P LG++ ITV A S +S
Sbjct: 772 NYEANIHTLKINGSE-----VIQAGGRKTNVWTIIPKKLGKVNITVVAESKQSSACPNEG 826
Query: 766 ---------DAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSE 816
D V Q LV+ EGIEK +QS L+ T+ S L P + V GS
Sbjct: 827 MEQQKLNWKDTVVQSFLVEPEGIEKERTQSFLI-CTEGAKASKQGVLDL--PNDVVEGSA 883
Query: 817 RVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKA 876
R T +GD+LG ++ L +++MPYG GEQN A + Y+LDYL +QLT+ ++ KA
Sbjct: 884 RGFFTVVGDILGLALQNLV-VLQMPYGSGEQNAALLASDTYVLDYLKSTEQLTEEVQSKA 942
Query: 877 LSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRT 936
+ GYQR+L ++ DGS+S F GS LSA + Y+ ID+NV +T
Sbjct: 943 FFLLSNGYQRQLSFKNSDGSYSVFWQQSQKGSIXLSALTFKTLERMKKYVFIDENVQKQT 1002
Query: 937 YTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIH 996
WL QK++G F + G++ + +GG++ ++LTAY+V ++ ++
Sbjct: 1003 LIWLSSQQKTSGCFKNDGQLFNHAWEGGDEEDISLTAYVVGMFFEAGLNFTFPALRNALF 1062
Query: 997 FLESEFSRGISDNYTLALITYALSSVGSPKAKEA-LNMLTWRAEQEGGMQFWVSSESKLS 1055
LE+ G+++ Y A++ YA + G K E+ L L A + + +W +
Sbjct: 1063 CLEAALDSGVTNGYNHAILAYAFALAGKEKQVESLLQTLDQSAPKLNNVIYWERERKPKT 1122
Query: 1056 DS------WQPRSLDIEVAAYALLSHFLQFQTSEGIP-------IMRWLSRQRNSLGGFA 1102
+ W P S E + Y LL+ S IP I++WL+++ NS GGF+
Sbjct: 1123 EEFPSFIPWAP-SAQTEKSCYVLLA-----VISRKIPDLTYASKIVQWLAQRMNSHGGFS 1176
Query: 1103 STQDTTVA--LKALSEFAALMNTER---TNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAE 1157
S Q V L A+ L E + Q TVT S S F ++ HNRLL+Q +E
Sbjct: 1177 SNQVINVGLILIAICLMQKLARGEEGLFSKDQNTVTFSSEGSSEIFQVNGHNRLLVQRSE 1236
Query: 1158 LAVVQPTAVNISANGFGFAICQLNVVYNV----KASGSSRRRRSIQN--QEAFDLDVAVK 1211
+ P + G G Q + YNV KASG S ++N AFDL V +K
Sbjct: 1237 VTQA-PGEYTVDVEGHGCTFIQATLKYNVLLPKKASGFSLSLEIVKNYSSTAFDLTVTLK 1295
Query: 1212 ----ENKDDLNHVDLNVCTSFS 1229
NK + +D+ + + F+
Sbjct: 1296 YTGIRNKSSMVVIDVKMLSGFT 1317
>gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain containing
8 [Homo sapiens]
Length = 1932
Score = 329 bits (844), Expect = 1e-89
Identities = 209/567 (36%), Positives = 310/567 (54%), Gaps = 47/567 (8%)
Query: 797 QSTLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNI 856
+S + + P + GSER + IGDV+GP++N L +L+R+P+GCGEQNMI+FAPN+
Sbjct: 1144 ESYSEAFTLGVPHGAIPGSERATASIIGDVMGPTLNHLNNLLRLPFGCGEQNMIHFAPNV 1203
Query: 857 YILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVL 916
++L YL K +QL+ ++ + ++ QGYQR+L Y+R+DGS+SAFG D SGS WL+AFVL
Sbjct: 1204 FVLKYLQKTQQLSPEVERETTDYLVQGYQRQLTYKRQDGSYSAFGERDASGSMWLTAFVL 1263
Query: 917 RCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIV 976
+ F +A +I +D L +W+ Q+++G F GRV++ ++QGG V LTAY+V
Sbjct: 1264 KSFAQARSFIFVDPRELAAAKSWIIQQQQADGSFLAVGRVLNKDIQGGIHGTVPLTAYVV 1323
Query: 977 TSLL--GYRKYQPNIDVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEALNML 1034
+LL G + ++ HFLES + D Y+ AL TYAL+ + SP A EAL L
Sbjct: 1324 VALLETGTASEEERGSTDKARHFLESAAPLAM-DPYSCALTTYALTLLRSPAAPEALRKL 1382
Query: 1035 TWRAEQEGGMQFWVSSES---------KLSD--SWQPRSLDIEVAAYALLSHFLQFQTSE 1083
A G+ W S S SD S S ++E+ AYALL++ L +
Sbjct: 1383 RSLAIMRDGVTHWSLSNSWDVDKGTFLSFSDRVSQSVVSAEVEMTAYALLTYTLLGDVAA 1442
Query: 1084 GIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNTERTNIQVTVTGPSSPSPVKF 1143
+P+++WLS+QRN+LGGF+STQDT VAL+AL+E+A L N+ V++ + F
Sbjct: 1443 ALPVVKWLSQQRNALGGFSSTQDTCVALQALAEYAILSYAGGINLTVSLASTNLDYQETF 1502
Query: 1144 LIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVVYNVK---ASGSSRRRRSIQN 1200
+ N+ +LQTA + + PT + +SA G G + Q++V YNV A + + S+Q
Sbjct: 1503 ELHRTNQKVLQTAAIPSL-PTGLFVSAKGDGCCLMQIDVTYNVPDPVAKPAFQLLVSLQE 1561
Query: 1201 QE----------------------AFDLDVAVKENKDDLNHVDLNVCTSFSGPGRSGMAL 1238
E A D D A ++ + V L VCT + G S MA+
Sbjct: 1562 PEAQGRPPPMPASAAEGSRGDWPPADDDDPAADQHHQEYK-VMLEVCTRWLHAGSSNMAV 1620
Query: 1239 MEVNLLSGFMVPSEA-----ISLSETVKKVEYDHGKLNLYLDSV-NETQFCVNIPAVRNF 1292
+EV LLSGF E+ + +K+ E ++ Y D + + CV A+R
Sbjct: 1621 LEVPLLSGFRADIESLEQLLLDKHMGMKRYEVAGRRVLFYFDEIPSRCLTCVRFRALREC 1680
Query: 1293 KVSNTQDASVSIVDYYEPRRQAVRSYN 1319
V T VS+ DYYEP +A R YN
Sbjct: 1681 VVGRTSALPVSVYDYYEPAFEATRFYN 1707
Score = 187 bits (475), Expect = 6e-47
Identities = 203/811 (25%), Positives = 331/811 (40%), Gaps = 154/811 (18%)
Query: 93 DPKSNLIQQWLSQQSDL-GVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVLPK 151
DP+ + + +W + G+ + +F LS P+LG+W I V++ Y +SF+V +YVLPK
Sbjct: 216 DPRGSRMIEWRHLKPFCCGITNMSFPLSDQPVLGEWFIFVEMQGHAYNKSFEVQKYVLPK 275
Query: 152 FEVTLQTPLYCSMNSKHLNGTITAKYTYGKPVKGD--VTLTFLPLSFWGKK--KNITKTF 207
FE+ + P Y GT+ A+YT+GKPV G + +T + ++ + + + +T
Sbjct: 276 FELLIDPPRYIQDLDACETGTVRARYTFGKPVAGALMINMTVNGVGYYSHEVGRPVLRTT 335
Query: 208 KINGSANFSFNDEEMKNVMDSSNGLSEYLDLSSPGPVEILTTVTESVTG---ISRNVSTN 264
KI GS +F +M + + G V I VT SV G ++ + ST
Sbjct: 336 KILGSRDFDICVRDM---------IPADVPEHFRGRVSIWAMVT-SVDGSQQVAFDDSTP 385
Query: 265 VFFKQHDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEY 324
V + D I D KP L + V+++ DG+ + +T YT
Sbjct: 386 VQRQLVD-IRYSKDTRKQFKPGLAYVGKVELSYPDGSPAEGVTVQIKAELTPKDNIYT-- 442
Query: 325 WSGSNSGNQKMEAVQKINYTVPQSGTFKIEFPILEDSSE---LQLKAYFLGSK------- 374
+ V Q G E P + S++ L+ K L K
Sbjct: 443 -----------------SEVVSQRGLVGFEIPSIPTSAQHVWLETKVMALNGKPVGAQYL 485
Query: 375 -SSMAVHSLFKSPSKTYIQLKTRDENIKVGSPFELVVSGNKRLK-ELSYMVVSRGQLVAV 432
S +++ S + SPS+ Y+QL+ ++VG V L Y V +RG +V
Sbjct: 486 PSYLSLGSWY-SPSQCYLQLQPPSHPLQVGEEAYFSVKSTCPCNFTLYYEVAARGNIVLS 544
Query: 433 GKQNS----------------------------------------TMFSLTPENSWTPKA 452
G+Q + T L S P
Sbjct: 545 GQQPAHTTQQRSKRAAPALEKPIRLTHLSETEPPPAPEAEVDVCVTSLHLAVTPSMVPLG 604
Query: 453 CVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSIVGI 512
++V+Y+ ++GE ++D L+ V+ F+N++ + +S + +P E V LRI + S V +
Sbjct: 605 RLLVFYVRENGEGVADSLQFAVETFFENQVSVTYSANETQPGEVVDLRIRAAR-GSCVCV 663
Query: 513 VAVDKSVNLMNASNDITMENVVHELELYNTG----------------------------- 543
AVDKSV L+ + +T V ELE Y+
Sbjct: 664 AAVDKSVYLLRSGFRLTPAQVFQELEDYDVSDSFGVSREDGPFWWAGLTAQRRRRSSVFP 723
Query: 544 YYLGMFMNSFAVFQECGLWVLTDANLTKDYIDGVYDNAEYAERFMEENEGHIVDIHDFSL 603
+ G+ +S F E GL V+TD DG E F + + G +V +
Sbjct: 724 WPWGITKDSGFAFTETGLVVMTDRVSLNHRQDGGLYTDEAVPAF-QPHTGSLVAVAPSRH 782
Query: 604 GSSPHVRKH--FPETWIWLDTNMGYRIYQ-EFEVTVPDSITSWVATGFVISEDLGLGLTT 660
RK FPETWIW N+ + V VPDSITSWV +S GLG+
Sbjct: 783 PPRTEKRKRTFFPETWIWHCLNISDPSGEGTLSVKVPDSITSWVGEAVALSTSQGLGI-A 841
Query: 661 TPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSN 720
P L+ F+PFF+ LP +IRGE+ + ++++NY+ EV + + +
Sbjct: 842 EPSLLKTFKPFFVDFMLPALIIRGEQVKIPLSVYNYMGTCAEVYMKLSVPKGIQFVGHPG 901
Query: 721 EINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTALS------------------- 761
+ + T + + V + + + + LG IT AL+
Sbjct: 902 KRHVT---KKMCVAPGEAEPIWVVLSFSDLGLNNITAKALAYGDTNCCRDGRSSKHPEEN 958
Query: 762 ------PTASDAVTQMILVKAEGIEKSYSQS 786
P D V + ++V+AEG+ ++Y+ S
Sbjct: 959 HADRRVPIGVDHVRRSVMVEAEGVPRAYTYS 989
>gi|178557739 complement component 4B preproprotein [Homo sapiens]
Length = 1744
Score = 239 bits (610), Expect = 1e-62
Identities = 235/838 (28%), Positives = 359/838 (42%), Gaps = 123/838 (14%)
Query: 609 VRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAF 668
VR FPE W+W + +Q + +PDS+T+W G +S+ GL TPV+L+ F
Sbjct: 774 VRSFFPENWLWRVETVDR--FQILTLWLPDSLTTWEIHGLSLSKTKGL-CVATPVQLRVF 830
Query: 669 QPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQ 728
+ F + L LP SV R E+ L ++NYL V V + + + G
Sbjct: 831 REFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLA------GGGGLA 884
Query: 729 QTLLVPSEDGATVLFPIRPTHLGEIPITVTALSP---TASDAVTQMILVKAEGIEKSYSQ 785
Q +LVP+ V F + PT + + V A DAV++++ ++ EG + +
Sbjct: 885 QQVLVPAGSARPVAFSVVPTAATAVSLKVVARGSFEFPVGDAVSKVLQIEKEGA--IHRE 942
Query: 786 SILLDLTDNRLQSTLKTLSF--SFPPNTVTGSE---RVQITAIG--DVLGP----SINGL 834
++ +L N L +TL + PN + + V++TA D LG S G+
Sbjct: 943 ELVYEL--NPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGV 1000
Query: 835 ASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQ---LTDNLKEKALSFMRQGYQRELLYQ 891
ASL+R+P GCGEQ MI AP + YL K +Q L K+ A+ +++GY R ++
Sbjct: 1001 ASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFR 1060
Query: 892 REDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFW 951
+ DGS++A+ STWL+AFVL+ A + L T WL Q+++G F
Sbjct: 1061 KADGSYAAW--LSRGSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQ 1118
Query: 952 DPGRVIHSELQG---GNKSPVTLTAYIVTSL-----------LGYRKYQPNIDVQESIHF 997
D VIH +QG GN V LTA++ +L K + + ++ F
Sbjct: 1119 DLSPVIHRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKASSF 1178
Query: 998 LESEFSRGISDNYTLALITYALSSVGSPKAKE--ALNMLTWRAEQEGGMQFWVSSESKLS 1055
L + S G+ + A+ YAL+ +P A N L A++ G +W S S
Sbjct: 1179 LGEKASAGLLGAHAAAITAYALTLTKAPADLRGVAHNNLMAMAQETGDNLYWGSVTGSQS 1238
Query: 1056 DSWQPR--------------SLDIEVAAYALLSHFLQFQTSE-GIPIMRWLSRQRNSLGG 1100
++ P +L IE AYALL L +E WL+RQ + GG
Sbjct: 1239 NAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGG 1298
Query: 1101 FASTQDTTVALKALSEF-AALMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLL-QTAEL 1158
F STQDT +AL ALS + A TE + VT++ + +NR + EL
Sbjct: 1299 FRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEEL 1358
Query: 1159 AVVQPTAVNISANGFGFAICQLNVVYNV-KASGSSRRRRSIQ-------------NQEAF 1204
+ +N+ G ++ YNV ++ + I+ N++
Sbjct: 1359 QFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYE 1418
Query: 1205 DLDVAVKENKDD--------------------------------LNHVDLNVCTSFSGP- 1231
D + KDD + V VC +G
Sbjct: 1419 DYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKV 1478
Query: 1232 GRSGMALMEVNLLSGFMV----PSEAISLSET-VKKVEYDHGKLNLYLDSVNETQFCVNI 1286
G SGMA+ +V LLSGF + SLS+ V E + + LY DSV ++ CV
Sbjct: 1479 GLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGF 1538
Query: 1287 PAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVK------LSSCDLCSDVQGCRP 1338
AV+ V Q AS ++ DYY P R+ Y + K L S ++C +G P
Sbjct: 1539 EAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCP 1596
Score = 73.6 bits (179), Expect = 1e-12
Identities = 110/464 (23%), Positives = 188/464 (40%), Gaps = 49/464 (10%)
Query: 125 GDWSIQVQVNDQTYYQS---FQVSEYVLPKFEVTLQTP--LYCSMNSKHLNGT---ITAK 176
G W I + +D S F+V +YVLP FEV + TP Y HL+ I A+
Sbjct: 211 GTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKI-TPGKPYILTVPGHLDEMQLDIQAR 269
Query: 177 YTYGKPVKGDVTLTFLPLSFWGKKKNI----TKTFKINGSANFSFNDEEMKNVMDSSN-G 231
Y YGKPV+G + F L GKK ++T +NG ++ S + E ++ ++ N G
Sbjct: 270 YIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKAEFQDALEKLNMG 329
Query: 232 LSEYLDLSSPGPVEILTTVTESVTGISRNVS-TNVFFKQHDYIIEFFDYTTVLKPSLNFT 290
+++ L + + + ES G T+ +F + ++ L P F
Sbjct: 330 ITDLQGLR----LYVAAAIIESPGGEMEEAELTSWYFVSSPFSLDLSKTKRHLVPGAPFL 385
Query: 291 ATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINYTVPQSGT 350
V G+ + + + V S + S + VQ I SG
Sbjct: 386 LQALVREMSGSP------ASGIPVKV---------SATVSSPGSVPEVQDIQQNTDGSGQ 430
Query: 351 FKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPS--KTYIQLKTRDEN-IKVGSPFE 407
I I + SELQL ++A ++ PS ++ ++ D +VG
Sbjct: 431 VSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIERPDSRPPRVGDTLN 490
Query: 408 L---VVSGNKRLKELSYMVVSRGQLVAVG---KQNSTMFSLTPENSWTPKACVIVYYIED 461
L V YM++SRGQ+V + K+ T S+ ++ P + +Y
Sbjct: 491 LNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLAPSFYFVAFYYHG 550
Query: 462 DGEIISDVLKIPVQL-VFKNKIKLYWSKVKA-EPSEKVSLRISVTQPDSIVGIVAVDKSV 519
D +++ L++ VQ + K++L K E V L + T ++V + A+D ++
Sbjct: 551 D-HPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLE-TDSLALVALGALDTAL 608
Query: 520 NLMNASN--DITMENVVHELELYNTGYYLGMFMNSFAVFQECGL 561
+ + + M V + Y+ G G ++ VFQ GL
Sbjct: 609 YAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGL 652
>gi|67190748 complement component 4A preproprotein [Homo sapiens]
Length = 1744
Score = 239 bits (609), Expect = 2e-62
Identities = 235/838 (28%), Positives = 361/838 (43%), Gaps = 123/838 (14%)
Query: 609 VRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAF 668
VR FPE W+W + +Q + +PDS+T+W G +S+ GL TPV+L+ F
Sbjct: 774 VRSFFPENWLWRVETVDR--FQILTLWLPDSLTTWEIHGLSLSKTKGL-CVATPVQLRVF 830
Query: 669 QPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQ 728
+ F + L LP SV R E+ L ++NYL V V + + + G
Sbjct: 831 REFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLA------GGGGLA 884
Query: 729 QTLLVPSEDGATVLFPIRPTHLGEIPITVTALSP---TASDAVTQMILVKAEGIEKSYSQ 785
Q +LVP+ V F + PT + + V A DAV++++ ++ EG + +
Sbjct: 885 QQVLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGA--IHRE 942
Query: 786 SILLDLTDNRLQSTLKTLSF--SFPPNTVTGSE---RVQITAIG--DVLGP----SINGL 834
++ +L N L +TL + PN + + V++TA D LG S G+
Sbjct: 943 ELVYEL--NPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGV 1000
Query: 835 ASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQ---LTDNLKEKALSFMRQGYQRELLYQ 891
ASL+R+P GCGEQ MI AP + YL K +Q L K+ A+ +++GY R ++
Sbjct: 1001 ASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFR 1060
Query: 892 REDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFW 951
+ DGS++A+ + D STWL+AFVL+ A + L T WL Q+++G F
Sbjct: 1061 KADGSYAAWLSRD--SSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQ 1118
Query: 952 DPGRVIHSELQG---GNKSPVTLTAYIVTSL-----------LGYRKYQPNIDVQESIHF 997
DP V+ +QG GN V LTA++ +L K + + ++ F
Sbjct: 1119 DPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSF 1178
Query: 998 LESEFSRGISDNYTLALITYALSSVGSP--KAKEALNMLTWRAEQEGGMQFWVSSESKLS 1055
L + S G+ + A+ YAL+ +P A N L A++ G +W S S
Sbjct: 1179 LGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTGSQS 1238
Query: 1056 DSWQPR--------------SLDIEVAAYALLSHFLQFQTSE-GIPIMRWLSRQRNSLGG 1100
++ P +L IE AYALL L +E WL+RQ + GG
Sbjct: 1239 NAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQASAWLTRQGSFQGG 1298
Query: 1101 FASTQDTTVALKALSEF-AALMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLL-QTAEL 1158
F STQDT +AL ALS + A TE + VT++ + +NR + EL
Sbjct: 1299 FRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEEL 1358
Query: 1159 AVVQPTAVNISANGFGFAICQLNVVYNV-KASGSSRRRRSIQ-------------NQEAF 1204
+ +N+ G ++ YNV ++ + I+ N++
Sbjct: 1359 QFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYE 1418
Query: 1205 DLDVAVKENKDD--------------------------------LNHVDLNVCTSFSGP- 1231
D + KDD + V VC +G
Sbjct: 1419 DYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKV 1478
Query: 1232 GRSGMALMEVNLLSGFMV----PSEAISLSET-VKKVEYDHGKLNLYLDSVNETQFCVNI 1286
G SGMA+ +V LLSGF + SLS+ V E + + LY DSV ++ CV
Sbjct: 1479 GLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGF 1538
Query: 1287 PAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVK------LSSCDLCSDVQGCRP 1338
AV+ V Q AS ++ DYY P R+ Y + K L S ++C +G P
Sbjct: 1539 EAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCP 1596
Score = 73.6 bits (179), Expect = 1e-12
Identities = 110/464 (23%), Positives = 188/464 (40%), Gaps = 49/464 (10%)
Query: 125 GDWSIQVQVNDQTYYQS---FQVSEYVLPKFEVTLQTP--LYCSMNSKHLNGT---ITAK 176
G W I + +D S F+V +YVLP FEV + TP Y HL+ I A+
Sbjct: 211 GTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKI-TPGKPYILTVPGHLDEMQLDIQAR 269
Query: 177 YTYGKPVKGDVTLTFLPLSFWGKKKNI----TKTFKINGSANFSFNDEEMKNVMDSSN-G 231
Y YGKPV+G + F L GKK ++T +NG ++ S + E ++ ++ N G
Sbjct: 270 YIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKAEFQDALEKLNMG 329
Query: 232 LSEYLDLSSPGPVEILTTVTESVTGISRNVS-TNVFFKQHDYIIEFFDYTTVLKPSLNFT 290
+++ L + + + ES G T+ +F + ++ L P F
Sbjct: 330 ITDLQGLR----LYVAAAIIESPGGEMEEAELTSWYFVSSPFSLDLSKTKRHLVPGAPFL 385
Query: 291 ATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINYTVPQSGT 350
V G+ + + + V S + S + VQ I SG
Sbjct: 386 LQALVREMSGSP------ASGIPVKV---------SATVSSPGSVPEVQDIQQNTDGSGQ 430
Query: 351 FKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPS--KTYIQLKTRDEN-IKVGSPFE 407
I I + SELQL ++A ++ PS ++ ++ D +VG
Sbjct: 431 VSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIERPDSRPPRVGDTLN 490
Query: 408 L---VVSGNKRLKELSYMVVSRGQLVAVG---KQNSTMFSLTPENSWTPKACVIVYYIED 461
L V YM++SRGQ+V + K+ T S+ ++ P + +Y
Sbjct: 491 LNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLAPSFYFVAFYYHG 550
Query: 462 DGEIISDVLKIPVQL-VFKNKIKLYWSKVKA-EPSEKVSLRISVTQPDSIVGIVAVDKSV 519
D +++ L++ VQ + K++L K E V L + T ++V + A+D ++
Sbjct: 551 D-HPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLE-TDSLALVALGALDTAL 608
Query: 520 NLMNASN--DITMENVVHELELYNTGYYLGMFMNSFAVFQECGL 561
+ + + M V + Y+ G G ++ VFQ GL
Sbjct: 609 YAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGL 652
>gi|239740684 PREDICTED: similar to C4A protein isoform 1 [Homo
sapiens]
Length = 1744
Score = 239 bits (609), Expect = 2e-62
Identities = 235/838 (28%), Positives = 361/838 (43%), Gaps = 123/838 (14%)
Query: 609 VRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAF 668
VR FPE W+W + +Q + +PDS+T+W G +S+ GL TPV+L+ F
Sbjct: 774 VRSFFPENWLWRVETVDR--FQILTLWLPDSLTTWEIHGLSLSKTKGL-CVATPVQLRVF 830
Query: 669 QPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQ 728
+ F + L LP SV R E+ L ++NYL V V + + + G
Sbjct: 831 REFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLA------GGGGLA 884
Query: 729 QTLLVPSEDGATVLFPIRPTHLGEIPITVTALSP---TASDAVTQMILVKAEGIEKSYSQ 785
Q +LVP+ V F + PT + + V A DAV++++ ++ EG + +
Sbjct: 885 QQVLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGA--IHRE 942
Query: 786 SILLDLTDNRLQSTLKTLSF--SFPPNTVTGSE---RVQITAIG--DVLGP----SINGL 834
++ +L N L +TL + PN + + V++TA D LG S G+
Sbjct: 943 ELVYEL--NPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGV 1000
Query: 835 ASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQ---LTDNLKEKALSFMRQGYQRELLYQ 891
ASL+R+P GCGEQ MI AP + YL K +Q L K+ A+ +++GY R ++
Sbjct: 1001 ASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFR 1060
Query: 892 REDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFW 951
+ DGS++A+ + D STWL+AFVL+ A + L T WL Q+++G F
Sbjct: 1061 KADGSYAAWLSRD--SSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQ 1118
Query: 952 DPGRVIHSELQG---GNKSPVTLTAYIVTSL-----------LGYRKYQPNIDVQESIHF 997
DP V+ +QG GN V LTA++ +L K + + ++ F
Sbjct: 1119 DPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSF 1178
Query: 998 LESEFSRGISDNYTLALITYALSSVGSP--KAKEALNMLTWRAEQEGGMQFWVSSESKLS 1055
L + S G+ + A+ YAL+ +P A N L A++ G +W S S
Sbjct: 1179 LGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTGSQS 1238
Query: 1056 DSWQPR--------------SLDIEVAAYALLSHFLQFQTSE-GIPIMRWLSRQRNSLGG 1100
++ P +L IE AYALL L +E WL+RQ + GG
Sbjct: 1239 NAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGG 1298
Query: 1101 FASTQDTTVALKALSEF-AALMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLL-QTAEL 1158
F STQDT +AL ALS + A TE + VT++ + +NR + EL
Sbjct: 1299 FRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEEL 1358
Query: 1159 AVVQPTAVNISANGFGFAICQLNVVYNV-KASGSSRRRRSIQ-------------NQEAF 1204
+ +N+ G ++ YNV ++ + I+ N++
Sbjct: 1359 QFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYE 1418
Query: 1205 DLDVAVKENKDD--------------------------------LNHVDLNVCTSFSGP- 1231
D + KDD + V VC +G
Sbjct: 1419 DYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKV 1478
Query: 1232 GRSGMALMEVNLLSGFMV----PSEAISLSET-VKKVEYDHGKLNLYLDSVNETQFCVNI 1286
G SGMA+ +V LLSGF + SLS+ V E + + LY DSV ++ CV
Sbjct: 1479 GLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGF 1538
Query: 1287 PAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVK------LSSCDLCSDVQGCRP 1338
AV+ V Q AS ++ DYY P R+ Y + K L S ++C +G P
Sbjct: 1539 EAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCP 1596
Score = 70.9 bits (172), Expect = 8e-12
Identities = 109/464 (23%), Positives = 187/464 (40%), Gaps = 49/464 (10%)
Query: 125 GDWSIQVQVNDQTYYQS---FQVSEYVLPKFEVTLQTP--LYCSMNSKHLNGT---ITAK 176
G W I + +D S F+V +YVLP FEV + TP Y HL+ I A+
Sbjct: 211 GTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKI-TPGKPYILTVPGHLDEMQLDIQAR 269
Query: 177 YTYGKPVKGDVTLTFLPLSFWGKKKNI----TKTFKINGSANFSFNDEEMKNVMDSSN-G 231
Y YGKPV+G + F L GKK ++T +NG ++ S + E ++ ++ N G
Sbjct: 270 YIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKAEFQDALEKLNMG 329
Query: 232 LSEYLDLSSPGPVEILTTVTESVTGISRNVS-TNVFFKQHDYIIEFFDYTTVLKPSLNFT 290
+++ L + + + E G T+ +F + ++ L P F
Sbjct: 330 ITDLQGLR----LYVAAAIIEYPGGEMEEAELTSWYFVSSPFSLDLSKTKRHLVPGAPFL 385
Query: 291 ATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINYTVPQSGT 350
V G+ + + + V S + S + VQ I SG
Sbjct: 386 LQALVREMSGSP------ASGIPVKV---------SATVSSPGSVPEVQDIQQNTDGSGQ 430
Query: 351 FKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPS--KTYIQLKTRDEN-IKVGSPFE 407
I I + SELQL ++A ++ PS ++ ++ D +VG
Sbjct: 431 VSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIEWPDSRPPRVGDTLN 490
Query: 408 L---VVSGNKRLKELSYMVVSRGQLVAVG---KQNSTMFSLTPENSWTPKACVIVYYIED 461
L V YM++SRGQ+V + K+ T S+ ++ P + +Y
Sbjct: 491 LNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLAPSFYFVAFYYHG 550
Query: 462 DGEIISDVLKIPVQL-VFKNKIKLYWSKVKA-EPSEKVSLRISVTQPDSIVGIVAVDKSV 519
D +++ L++ VQ + K++L K E V L + T ++V + A+D ++
Sbjct: 551 D-HPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLE-TDSLALVALGALDTAL 608
Query: 520 NLMNASN--DITMENVVHELELYNTGYYLGMFMNSFAVFQECGL 561
+ + + M V + Y+ G G ++ VFQ GL
Sbjct: 609 YAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGL 652
>gi|239740686 PREDICTED: similar to C4A protein isoform 2 [Homo
sapiens]
Length = 1698
Score = 235 bits (599), Expect = 2e-61
Identities = 223/801 (27%), Positives = 347/801 (43%), Gaps = 95/801 (11%)
Query: 609 VRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAF 668
VR FPE W+W + +Q + +PDS+T+W G +S+ GL TPV+L+ F
Sbjct: 774 VRSFFPENWLWRVETVDR--FQILTLWLPDSLTTWEIHGLSLSKTKGL-CVATPVQLRVF 830
Query: 669 QPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQ 728
+ F + L LP SV R E+ L ++NYL V V + + + G
Sbjct: 831 REFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLA------GGGGLA 884
Query: 729 QTLLVPSEDGATVLFPIRPTHLGEIPITVTALSP---TASDAVTQMILVKAEGIEKSYSQ 785
Q +LVP+ V F + PT + + V A DAV++++ ++ EG + +
Sbjct: 885 QQVLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGA--IHRE 942
Query: 786 SILLDLTDNRLQSTLKTLSF--SFPPNTVTGSE---RVQITAIG--DVLGP----SINGL 834
++ +L N L +TL + PN + + V++TA D LG S G+
Sbjct: 943 ELVYEL--NPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGV 1000
Query: 835 ASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQ---LTDNLKEKALSFMRQGYQRELLYQ 891
ASL+R+P GCGEQ MI AP + YL K +Q L K+ A+ +++GY R ++
Sbjct: 1001 ASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFR 1060
Query: 892 REDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFW 951
+ DGS++A+ + D STWL+AFVL+ A + L T WL Q+++G F
Sbjct: 1061 KADGSYAAWLSRD--SSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQ 1118
Query: 952 DPGRVIHSELQG---GNKSPVTLTAYIVTSL-----------LGYRKYQPNIDVQESIHF 997
DP V+ +QG GN V LTA++ +L K + + ++ F
Sbjct: 1119 DPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSF 1178
Query: 998 LESEFSRGISDNYTLALITYALSSVGSP--KAKEALNMLTWRAEQEGGMQFWVSSESKLS 1055
L + S G+ + A+ YAL+ +P A N L A++ G +W S S
Sbjct: 1179 LGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTGSQS 1238
Query: 1056 DSWQPR--------------SLDIEVAAYALLSHFLQFQTSE-GIPIMRWLSRQRNSLGG 1100
++ P +L IE AYALL L +E WL+RQ + GG
Sbjct: 1239 NAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGG 1298
Query: 1101 FASTQDTTVALKALSEF-AALMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLL-QTAEL 1158
F STQDT +AL ALS + A TE + VT++ + +NR + EL
Sbjct: 1299 FRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEEL 1358
Query: 1159 AVVQPTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAV-------- 1210
+ +N+ G ++ YNV ++N DL + V
Sbjct: 1359 QFSLGSKINVKVGGNSKGTLKVLRTYNV---------LDMKNTTCQDLQIEVTVKGHVEY 1409
Query: 1211 -KENKDDLNHVDLNVCTSFSGPGRSGMALMEVNLLSG-----FMVPSEAISLSET-VKKV 1263
E +D + + + P + + L G + SLS+ V
Sbjct: 1410 TMEANEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKLTSLSDRYVSHF 1469
Query: 1264 EYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVK 1323
E + + LY DSV ++ CV AV+ V Q AS ++ DYY P R+ Y + K
Sbjct: 1470 ETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSK 1529
Query: 1324 ------LSSCDLCSDVQGCRP 1338
L S ++C +G P
Sbjct: 1530 SRLLATLCSAEVCQCAEGKCP 1550
Score = 70.9 bits (172), Expect = 8e-12
Identities = 109/464 (23%), Positives = 187/464 (40%), Gaps = 49/464 (10%)
Query: 125 GDWSIQVQVNDQTYYQS---FQVSEYVLPKFEVTLQTP--LYCSMNSKHLNGT---ITAK 176
G W I + +D S F+V +YVLP FEV + TP Y HL+ I A+
Sbjct: 211 GTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKI-TPGKPYILTVPGHLDEMQLDIQAR 269
Query: 177 YTYGKPVKGDVTLTFLPLSFWGKKKNI----TKTFKINGSANFSFNDEEMKNVMDSSN-G 231
Y YGKPV+G + F L GKK ++T +NG ++ S + E ++ ++ N G
Sbjct: 270 YIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKAEFQDALEKLNMG 329
Query: 232 LSEYLDLSSPGPVEILTTVTESVTGISRNVS-TNVFFKQHDYIIEFFDYTTVLKPSLNFT 290
+++ L + + + E G T+ +F + ++ L P F
Sbjct: 330 ITDLQGLR----LYVAAAIIEYPGGEMEEAELTSWYFVSSPFSLDLSKTKRHLVPGAPFL 385
Query: 291 ATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINYTVPQSGT 350
V G+ + + + V S + S + VQ I SG
Sbjct: 386 LQALVREMSGSP------ASGIPVKV---------SATVSSPGSVPEVQDIQQNTDGSGQ 430
Query: 351 FKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPS--KTYIQLKTRDEN-IKVGSPFE 407
I I + SELQL ++A ++ PS ++ ++ D +VG
Sbjct: 431 VSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIEWPDSRPPRVGDTLN 490
Query: 408 L---VVSGNKRLKELSYMVVSRGQLVAVG---KQNSTMFSLTPENSWTPKACVIVYYIED 461
L V YM++SRGQ+V + K+ T S+ ++ P + +Y
Sbjct: 491 LNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLAPSFYFVAFYYHG 550
Query: 462 DGEIISDVLKIPVQL-VFKNKIKLYWSKVKA-EPSEKVSLRISVTQPDSIVGIVAVDKSV 519
D +++ L++ VQ + K++L K E V L + T ++V + A+D ++
Sbjct: 551 D-HPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLE-TDSLALVALGALDTAL 608
Query: 520 NLMNASN--DITMENVVHELELYNTGYYLGMFMNSFAVFQECGL 561
+ + + M V + Y+ G G ++ VFQ GL
Sbjct: 609 YAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGL 652
>gi|115298678 complement component 3 precursor [Homo sapiens]
Length = 1663
Score = 224 bits (572), Expect = 3e-58
Identities = 212/785 (27%), Positives = 360/785 (45%), Gaps = 85/785 (10%)
Query: 610 RKHFPETWIWLDTNMGYR-----IYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVE 664
R FPE+W+W ++ + + + DSIT+W +S+ G+ P E
Sbjct: 764 RSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGI-CVADPFE 822
Query: 665 LQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIE--KSDKFDILMTSNEI 722
+ Q FFI L LPYSV+R E+ + ++NY + E+KV +E + F L T+
Sbjct: 823 VTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNY-RQNQELKVRVELLHNPAFCSLATTKR- 880
Query: 723 NATGHQQTLLVPSEDGATVLFPIRP--THLGEIPITVTALSPTASDAVTQMILVKAEGIE 780
HQQT+ +P + +V + I P T L E+ + SD V + + V EGI
Sbjct: 881 ---RHQQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHFISDGVRKSLKVVPEGIR 937
Query: 781 KSYSQSI-LLDLTDNRLQSTLK------TLSFSFPPNTVTGSERVQITAIGDVLGPSING 833
+ + ++ LD + K LS P +Q T + + +++
Sbjct: 938 MNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRILLQGTPVAQMTEDAVDA 997
Query: 834 --LASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEK---ALSFMRQGYQREL 888
L LI P GCGEQNMI P + + YL + +Q EK AL +++GY ++L
Sbjct: 998 ERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQL 1057
Query: 889 LYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWL-KGHQKSN 947
+++ +F+AF P STWL+A+V++ F A I ID VL WL QK +
Sbjct: 1058 AFRQPSSAFAAFVKRAP--STWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPD 1115
Query: 948 GEFWDPGRVIHSELQGG----NKSPVTLTAYIVTSLLGYR---KYQPNI---DVQESIHF 997
G F + VIH E+ GG N+ + LTA+++ SL + + Q N + ++ F
Sbjct: 1116 GVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKDICEEQVNSLPGSITKAGDF 1175
Query: 998 LESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDS 1057
LE+ + + +YT+A+ YAL+ +G K LT ++ W +L
Sbjct: 1176 LEANY-MNLQRSYTVAIAGYALAQMGRLKGPLLNKFLTTAKDKNR----WEDPGKQL--- 1227
Query: 1058 WQPRSLDIEVAAYALLSHFLQFQTSEGI-PIMRWLSRQRNSLGGFASTQDTTVALKALSE 1116
++E +YALL+ LQ + + + P++RWL+ QR GG+ STQ T + +AL++
Sbjct: 1228 -----YNVEATSYALLA-LLQLKDFDFVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQ 1281
Query: 1117 FAA-LMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNISANGFGF 1175
+ + + N+ V++ PS S + I + LL++ E + ++A G G
Sbjct: 1282 YQKDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLRSEE--TKENEGFTVTAEGKGQ 1339
Query: 1176 AICQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAV-------KENKDDLNHVDLNVCTSF 1228
+ +Y+ KA + FDL V + K +D N + L +CT +
Sbjct: 1340 GTLSVVTMYHAKAKDQLTCNK-------FDLKVTIKPAPETEKRPQDAKNTMILEICTRY 1392
Query: 1229 SGPGRSGMALMEVNLLSGFMVPSE-----AISLSETVKKVEY-----DHGKLNLYLDSVN 1278
G + M+++++++++GF ++ A + + K E D L +YLD V+
Sbjct: 1393 RGDQDATMSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVS 1452
Query: 1279 ETQ-FCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVKLSSCD-LCSDVQGC 1336
++ C+ + F V Q +V + YY R Y+ E + + LC D + C
Sbjct: 1453 HSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRD-ELC 1511
Query: 1337 RPCED 1341
R E+
Sbjct: 1512 RCAEE 1516
Score = 85.1 bits (209), Expect = 4e-16
Identities = 127/569 (22%), Positives = 238/569 (41%), Gaps = 74/569 (13%)
Query: 20 LAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTVSVLEAEGV 79
+++ G F+ T I PG V + TV +LL + V++ EG+
Sbjct: 123 VSLQSGYLFIQTDKTIYTPGSTVLYRI---------FTVNHKLLPVGRTVMVNIENPEGI 173
Query: 80 FEKGSFKTLTLPSDPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVND---Q 136
K Q LS Q+ LGV+ ++ + +G W I+ + Q
Sbjct: 174 PVK-----------------QDSLSSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQ 216
Query: 137 TYYQSFQVSEYVLPKFEVTLQTP--LYCSMNSKHLNGTITAKYTYGKPVKGDVTLTFLPL 194
+ F+V EYVLP FEV ++ Y N K L TITA++ YGK V+G + F +
Sbjct: 217 VFSTEFEVKEYVLPSFEVIVEPTEKFYYIYNEKGLEVTITARFLYGKKVEGTAFVIF-GI 275
Query: 195 SFWGKKKNITKTFK----INGSANFSFNDEEMKNVMDS-SNGLSEYLDLSSPGPVEILTT 249
++ ++ ++ K +GS + K ++D N +E DL T
Sbjct: 276 QDGEQRISLPESLKRIPIEDGSGEVVLS---RKVLLDGVQNPRAE--DLVGKSLYVSATV 330
Query: 250 VTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVLKPSLNFTATVKVTRADGN---QLTLE 306
+ S + + + + + Y I F KP + F V VT DG+ ++ +
Sbjct: 331 ILHSGSDMVQAERSGIPIVTSPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVA 390
Query: 307 ERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINYTVPQSGTFKIEFPILEDSSE-LQ 365
+ + V ++TQ + S + +QK ++ TV T K E E ++ +Q
Sbjct: 391 VQGEDTVQSLTQGDGVAKLSINTHPSQK-----PLSITV---RTKKQELSEAEQATRTMQ 442
Query: 366 LKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVGSPFELVVSGNKRLKELSYMVVS 425
Y S+ +H S +T ++ E + V + + +++ +Y++++
Sbjct: 443 ALPYSTVGNSNNYLH---LSVLRTELR---PGETLNVNFLLRMDRAHEAKIRYYTYLIMN 496
Query: 426 RGQLVAVGK------QNSTMFSLTPENSWTPKACVIVYY----IEDDGEIISDVLKIPVQ 475
+G+L+ G+ Q+ + L+ + P ++ YY E+++D + + V+
Sbjct: 497 KGRLLKAGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGASGQREVVADSVWVDVK 556
Query: 476 --LVFKNKIKLYWSKVKAE-PSEKVSLRISVTQPDSIVGIVAVDKSVNLMNASNDITMEN 532
V +K S+ + P ++++L+I +V +VAVDK V ++N N +T
Sbjct: 557 DSCVGSLVVKSGQSEDRQPVPGQQMTLKIEGDHGARVV-LVAVDKGVFVLNKKNKLTQSK 615
Query: 533 VVHELELYNTGYYLGMFMNSFAVFQECGL 561
+ +E + G G + VF + GL
Sbjct: 616 IWDVVEKADIGCTPGSGKDYAGVFSDAGL 644
>gi|38016947 complement component 5 preproprotein [Homo sapiens]
Length = 1676
Score = 183 bits (465), Expect = 9e-46
Identities = 190/783 (24%), Positives = 356/783 (45%), Gaps = 90/783 (11%)
Query: 605 SSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVE 664
S P +R +FPE+W+W + R ++ + +PDS+T+W G IS + G+ + T V+
Sbjct: 761 SKPEIRSYFPESWLWEVHLVPRR--KQLQFALPDSLTTWEIQGVGIS-NTGICVADT-VK 816
Query: 665 LQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINA 724
+ F+ F+ +N+PYSV+RGE+ L+ T++NY + V K + + TS E
Sbjct: 817 AKVFKDVFLEMNIPYSVVRGEQIQLKGTVYNYRTSGMQFCV---KMSAVEGICTS-ESPV 872
Query: 725 TGHQQTLL-------VPSEDGATVLFPIRPTHLGEIPITVTALSPTASDAVTQMILVKAE 777
HQ T V V F + P +G I + + + + + + V E
Sbjct: 873 IDHQGTKSSKCVRQKVEGSSSHLVTFTVLPLEIGLHNINFSLETWFGKEILVKTLRVVPE 932
Query: 778 GIEKSYSQSILLDLTDNRLQSTL---KTLSFSFPPNTVTGSERVQITAI-----GDVLGP 829
G+++ + LD + T+ K + P + V +E +I ++ G++L
Sbjct: 933 GVKRESYSGVTLD--PRGIYGTISRRKEFPYRIPLDLVPKTEIKRILSVKGLLVGEILSA 990
Query: 830 SIN--GLASLIRMPYGCGEQNMINFAPNIYILDYLT--------------KKKQLTDNLK 873
++ G+ L +P G E +++ P Y+ YL +K++L LK
Sbjct: 991 VLSQEGINILTHLPKGSAEAELMSVVPVFYVFHYLETGNHWNIFHSDPLIEKQKLKKKLK 1050
Query: 874 EKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVL 933
E LS M Y+ D S+S + S STWL+AF LR + + Y++ +QN +
Sbjct: 1051 EGMLSIMS--------YRNADYSYSVWKG--GSASTWLTAFALRVLGQVNKYVEQNQNSI 1100
Query: 934 HRTYTWL-KGHQKSNGEFWDPGRVIHSELQG-----GNKSPVTLTAYIVTSLLGYRKYQP 987
+ WL + +Q NG F + + +LQG ++ + LTA+ V + P
Sbjct: 1101 CNSLLWLVENYQLDNGSFKENSQYQPIKLQGTLPVEARENSLYLTAFTVIGIRKAFDICP 1160
Query: 988 NIDVQESIHFLES---EFSRGISDNYTLALITYALS--SVGSPKAKEALNMLTWRAEQEG 1042
+ + ++ ++ E + +TLA+ YALS P+ + ++ L A +G
Sbjct: 1161 LVKIDTALIKADNFLLENTLPAQSTFTLAISAYALSLGDKTHPQFRSIVSALKREALVKG 1220
Query: 1043 G---MQFWVSS----ESKLSDSWQPRSLDIEVAAYALLSHFLQFQTSEGIPIMRWLSRQR 1095
+FW + +S + ++ R +E AYALL+ + P+++WLS ++
Sbjct: 1221 NPPIYRFWKDNLQHKDSSVPNTGTARM--VETTAYALLTSLNLKDINYVNPVIKWLSEEQ 1278
Query: 1096 NSLGGFASTQDTTVALKALSEFAALMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQT 1155
GGF STQDT A++ L+E++ L+ R ++ + V+ + + + T L +
Sbjct: 1279 RYGGGFYSTQDTINAIEGLTEYSLLVKQLRLSMDIDVSYKHKGALHNYKM-TDKNFLGRP 1337
Query: 1156 AELAVVQPTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQNQ-EAFDLDVAVKENK 1214
E+ + V + GFG + ++V V + +S S + + D++ +
Sbjct: 1338 VEVLLNDDLIV---STGFGSGLATVHVTTVVHKTSTSEEVCSFYLKIDTQDIEASHYRGY 1394
Query: 1215 DDLNHVDLNVCTSFSGPGR------SGMALMEVNLLSGFMVPSEAI-SLSETVKKVEYDH 1267
+ ++ + C S+ P R S A+M+++L +G E + +L E V ++ D+
Sbjct: 1395 GNSDYKRIVACASYK-PSREESSSGSSHAVMDISLPTGISANEEDLKALVEGVDQLFTDY 1453
Query: 1268 ----GKLNLYLDSVNETQF-CVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYN-SE 1321
G + L L+S+ + F CV F+V A+ ++ +Y+ P +Q Y+ S
Sbjct: 1454 QIKDGHVILQLNSIPSSDFLCVRFRIFELFEVGFLSPATFTVYEYHRPDKQCTMFYSTSN 1513
Query: 1322 VKL 1324
+K+
Sbjct: 1514 IKI 1516
Score = 99.4 bits (246), Expect = 2e-20
Identities = 128/512 (25%), Positives = 225/512 (43%), Gaps = 54/512 (10%)
Query: 93 DPKSNLIQQWLSQQSDLGVIS-KTFQLSSHPILGDWSIQVQVNDQ---TYYQSFQVSEYV 148
DP+ + + + + +G+IS F++ S+P G W+I+ + + T F+V EYV
Sbjct: 165 DPEGSEVDM-VEEIDHIGIISFPDFKIPSNPRYGMWTIKAKYKEDFSTTGTAYFEVKEYV 223
Query: 149 LPKFEVTLQTPLYCSM---NSKHLNGTITAKYTYGKPV-KGDVTLTF-LPLSFWGKKKNI 203
LP F V+++ P Y + N K+ TI A+Y Y K V + DV +TF + +K +
Sbjct: 224 LPHFSVSIE-PEYNFIGYKNFKNFEITIKARYFYNKVVTEADVYITFGIREDLKDDQKEM 282
Query: 204 TK-----TFKINGSANFSFNDEEMKNVMDSSNGLSEY-LDLSSPGPVEILTTVTESVTGI 257
+ T ING A +F+ E + LS Y L+ + + I TV ES G
Sbjct: 283 MQTAMQNTMLINGIAQVTFDSE------TAVKELSYYSLEDLNNKYLYIAVTVIESTGGF 336
Query: 258 SRNVS-TNVFFKQHDYIIEFFDYTTVLKPSLNFTATVKVTRA-----DGNQLTLEERRNN 311
S + + Y + LKP + + V+V + G +TL +
Sbjct: 337 SEEAEIPGIKYVLSPYKLNLVATPLFLKPGIPYPIKVQVKDSLDQLVGGVPVTLNAQ--- 393
Query: 312 VVITVTQRNYTEYWSGSNSGNQKMEAVQKINYTVPQSGTFKIEFPILEDSSELQLKAYFL 371
T+ T S S + + V +P SG +EF + D+ +L +
Sbjct: 394 ---TIDVNQETSDLDPSKSVTRVDDGVASFVLNLP-SGVTVLEFNVKTDAPDLPEENQAR 449
Query: 372 GSKSSMAVHSLFKSPSKTYIQLKTRDENIKVGSPFELVVSGNK----RLKELSYMVVSRG 427
++A SL S S YI + + VG ++V+ ++ +Y+++S+G
Sbjct: 450 EGYRAIAYSSL--SQSYLYIDWTDNHKALLVGEHLNIIVTPKSPYIDKITHYNYLILSKG 507
Query: 428 QLVAVGKQNS------TMFSLTPENSWTPKACVIVYYI---EDDGEIISDVLKIPVQLVF 478
+++ G + ++ + P + ++VYYI E E++SD + + ++
Sbjct: 508 KIIHFGTREKFSDASYQSINIPVTQNMVPSSRLLVYYIVTGEQTAELVSDSVWLNIEEKC 567
Query: 479 KNKIKLYWS--KVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMNASNDITMENVVHE 536
N+++++ S P + VSL ++ T DS V + AVD +V + +E V
Sbjct: 568 GNQLQVHLSPDADAYSPGQTVSLNMA-TGMDSWVALAAVDSAVYGVQRGAKKPLERVFQF 626
Query: 537 LELYNTGYYLGMFMNSFAVFQECGLWVLTDAN 568
LE + G G +N+ VF GL LT+AN
Sbjct: 627 LEKSDLGCGAGGGLNNANVFHLAGLTFLTNAN 658
>gi|169218213 PREDICTED: similar to complement component C3, partial
[Homo sapiens]
Length = 1295
Score = 180 bits (456), Expect = 9e-45
Identities = 158/541 (29%), Positives = 258/541 (47%), Gaps = 55/541 (10%)
Query: 610 RKHFPETWIWLDTNMGYR-----IYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVE 664
R FPE+W+W ++ + + + DSIT+W +S+ G+ P E
Sbjct: 764 RSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGI-CVADPFE 822
Query: 665 LQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIE--KSDKFDILMTSNEI 722
+ Q FFI L LPYSV+R E+ + ++NY + E+KV +E + F L T+
Sbjct: 823 VTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNY-RQNQELKVRVELLHNPAFCSLATTKR- 880
Query: 723 NATGHQQTLLVPSEDGATVLFPIRP--THLGEIPITVTALSPTASDAVTQMILVKAEGIE 780
HQQT+ +P + +V + I P T L E+ + SD V + + V EGI
Sbjct: 881 ---RHQQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHFISDGVRKSLKVVPEGIR 937
Query: 781 KSYSQSI-LLDLTDNRLQSTLK------TLSFSFPPNTVTGSERVQITAIGDVLGPSING 833
+ + ++ LD + K LS P +Q T + + +++
Sbjct: 938 MNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRILLQGTPVAQMTEDAVDA 997
Query: 834 --LASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEK---ALSFMRQGYQREL 888
L LI P GCGEQNMI P + + YL + +Q EK AL +++GY ++L
Sbjct: 998 ERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQL 1057
Query: 889 LYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWL-KGHQKSN 947
+++ +F+AF P STWL+A+V++ F A I ID VL WL QK +
Sbjct: 1058 AFRQPSSAFAAFVKRAP--STWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPD 1115
Query: 948 GEFWDPGRVIHSELQGG----NKSPVTLTAYIVTSLLGYR---KYQPNI---DVQESIHF 997
G F + VIH E+ GG N+ + LTA+++ SL + + Q N + ++ F
Sbjct: 1116 GVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKDICEEQVNSLPGSITKAGDF 1175
Query: 998 LESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDS 1057
LE+ + + +YT+A+ YAL+ +G K LT ++ W +L
Sbjct: 1176 LEANY-MNLQRSYTVAIAGYALAQMGRLKGPLLNKFLTTAKDKNR----WEDPGKQL--- 1227
Query: 1058 WQPRSLDIEVAAYALLSHFLQFQTSEGI-PIMRWLSRQRNSLGGFASTQDTTVALKALSE 1116
++E +YALL+ LQ + + + P++RWL+ QR GG+ STQ T + +AL++
Sbjct: 1228 -----YNVEATSYALLA-LLQLKDFDFVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQ 1281
Query: 1117 F 1117
+
Sbjct: 1282 Y 1282
Score = 86.3 bits (212), Expect = 2e-16
Identities = 126/568 (22%), Positives = 236/568 (41%), Gaps = 72/568 (12%)
Query: 20 LAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTVSVLEAEGV 79
+++ G F+ T I PG V + TV +LL + V++ EG+
Sbjct: 123 VSLQSGYLFIQTDKTIYTPGSTVLYRI---------FTVNHKLLPVGRTVMVNIENPEGI 173
Query: 80 FEKGSFKTLTLPSDPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVND---Q 136
K Q LS Q+ LGV+ ++ + +G W I+ + Q
Sbjct: 174 PVK-----------------QDSLSSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQ 216
Query: 137 TYYQSFQVSEYVLPKFEVTLQTP--LYCSMNSKHLNGTITAKYTYGKPVKGDVTLTFLPL 194
+ F+V EYVLP FEV ++ Y N K L TITA++ YGK V+G + F +
Sbjct: 217 VFSTEFEVKEYVLPSFEVIVEPTEKFYYIYNEKGLEVTITARFLYGKKVEGTAFVIF-GI 275
Query: 195 SFWGKKKNITKTFK----INGSANFSFNDEEMKNVMDSSNGLSEYLDLSSPGPVEILTTV 250
++ ++ ++ K +GS + K ++D L DL T +
Sbjct: 276 QDGEQRISLPESLKRIPIEDGSGEVVLS---RKVLLDGVQNLRAE-DLVGKSLYVSATVI 331
Query: 251 TESVTGISRNVSTNVFFKQHDYIIEFFDYTTVLKPSLNFTATVKVTRADGN---QLTLEE 307
S + + + + + Y I F KP + F V VT DG+ ++ +
Sbjct: 332 LHSGSDMVQAERSGIPIVTSPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAV 391
Query: 308 RRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINYTVPQSGTFKIEFPILEDSSE-LQL 366
+ + V ++TQ + S + +QK ++ TV T K E E ++ +Q
Sbjct: 392 QGEDTVQSLTQGDGVAKLSINTHPSQK-----PLSITV---RTKKQELSEAEQATRTMQA 443
Query: 367 KAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVGSPFELVVSGNKRLKELSYMVVSR 426
Y S+ +H S +T ++ E + V + + +++ +Y+++++
Sbjct: 444 LPYSTVGNSNNYLH---LSVLRTELR---PGETLNVNFLLRMDRAHEAKIRYYTYLIMNK 497
Query: 427 GQLVAVGK------QNSTMFSLTPENSWTPKACVIVYY----IEDDGEIISDVLKIPVQ- 475
G+L+ G+ Q+ + L+ + P ++ YY E+++D + + V+
Sbjct: 498 GRLLKAGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGASGQREVVADSVWVDVKD 557
Query: 476 -LVFKNKIKLYWSKVKAE-PSEKVSLRISVTQPDSIVGIVAVDKSVNLMNASNDITMENV 533
V +K S+ + P ++++L+I +V +VAVDK V ++N N +T +
Sbjct: 558 SCVGSLVVKSGQSEDRQPVPGQQMTLKIEGDHGARVV-LVAVDKGVFVLNKKNKLTQSKI 616
Query: 534 VHELELYNTGYYLGMFMNSFAVFQECGL 561
+E + G G + VF + GL
Sbjct: 617 WDVVEKADIGCTPGSGKDYAGVFSDAGL 644
>gi|239750255 PREDICTED: similar to ovostatin-2 [Homo sapiens]
Length = 750
Score = 177 bits (450), Expect = 5e-44
Identities = 141/500 (28%), Positives = 228/500 (45%), Gaps = 74/500 (14%)
Query: 440 FSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSL 499
F L+ P A + VY + GEI++D ++ V FK+K+ + +S + P SL
Sbjct: 146 FPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQVDKCFKHKVNIKFSNEQGLPGSNASL 205
Query: 500 RISVTQPDSIVGIVAVDKSVNLMNASNDITME---NVVHELELYNTGYY----------- 545
+ P + AVD +V L+ + ++ E N+V +E Y Y+
Sbjct: 206 YLQAA-PVLFCALGAVDGNVLLLKSEQQLSAESVYNMVPSIEPYGYFYHGLNLDDGKEDP 264
Query: 546 ----LGMFMNS--------------FAVFQECGLWVLTDANLTKDYIDGVYDNAEYAERF 587
MF N + + + GL V T+ + K + + +
Sbjct: 265 CIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKVFTNLHYRKPEVCVMERRLPLPKPL 324
Query: 588 MEENEG----HIVDIHDFSLGSSPH------------VRKHFPETWIWLDTNMGYRIYQE 631
E E H V S G VR +FPETW+W ++
Sbjct: 325 YLETENYGPMHSVPSRIASSGIRGENADYVEQAIIQTVRTNFPETWMWDLVSVDSSGSAN 384
Query: 632 FEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEI 691
+PD+IT W A+GF ++ D+G G+++T L+ QPFFI + P+SV++ E+F L +
Sbjct: 385 LSFLIPDTITQWEASGFCVNGDVGFGISSTTT-LEVSQPFFIEIASPFSVVQNEQFDLIV 443
Query: 692 TIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLG 751
F+YL E+ V +E+S ++ + + +IN + ++ + T ++ I P LG
Sbjct: 444 NAFSYLNTCVEISVQVEESQNYEANINTWKINGSE-----VIQAGGRKTNIWTIIPKKLG 498
Query: 752 EIPITVTALSPTAS---------------DAVTQMILVKAEGIEKSYSQSILLDLTDNRL 796
++ ITV A S +S D V + LV+ EGIEK +QS L+ T+
Sbjct: 499 KVNITVVAESKQSSACPNEGMEQQKLNWKDTVVKSFLVEPEGIEKERTQSFLI-CTEGAK 557
Query: 797 QSTLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNI 856
S L P + V GS R T +GD+LG ++ L +++MPYG GEQN A +
Sbjct: 558 ASKQGVL--DLPNDVVEGSARGFFTVVGDILGLAMQNLV-VLQMPYGGGEQNAALLASDT 614
Query: 857 YILDYLTKKKQLTDNLKEKA 876
Y+LDYL +QLT+ ++ KA
Sbjct: 615 YVLDYLKSTEQLTEEVQSKA 634
>gi|239758130 PREDICTED: similar to complement component 4B (Childo
blood group), partial [Homo sapiens]
Length = 666
Score = 117 bits (294), Expect = 6e-26
Identities = 136/518 (26%), Positives = 204/518 (39%), Gaps = 91/518 (17%)
Query: 912 SAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQG---GNKSP 968
+AFVL+ A + + L T WL Q+++G F D VIH +QG GN
Sbjct: 1 TAFVLKVLSLAQEQVGGSREKLQETSNWLLSQQQADGSFQDLSPVIHRSMQGGLVGNDET 60
Query: 969 VTLTAYIVTSL-----------LGYRKYQPNIDVQESIHFLESEFSRGISDNYTLALITY 1017
V LTA++ +L K + + ++ FL + S G+ + A+ Y
Sbjct: 61 VALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSFLGEKASAGLLGAHAAAITAY 120
Query: 1018 ALSSVGSPKAKE--ALNMLTWRAEQEGGMQFWVSSESKLSDSWQPR-------------- 1061
AL+ +P A N L A++ G +W S S++ P
Sbjct: 121 ALTLTKAPADLRGVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDPMPQAP 180
Query: 1062 SLDIEVAAYALLSHFLQFQTSE-GIPIMRWLSRQRNSLGGFASTQDTTVALKALSEF-AA 1119
+L IE AYALL L +E WL+RQ + GGF STQDT +AL ALS + A
Sbjct: 181 ALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIA 240
Query: 1120 LMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLL-QTAELAVVQPTAVNISANGFGFAIC 1178
TE + VT++ + +NR + EL + +N+ G
Sbjct: 241 SHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTL 300
Query: 1179 QLNVVYNV-KASGSSRRRRSIQ-------------NQEAFDLDVAVKENKDD-------- 1216
++ YNV ++ + I+ N++ D + KDD
Sbjct: 301 KVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPV 360
Query: 1217 ------------------------LNHVDLNVCTSFSGP-GRSGMALMEVNLLSGFMV-- 1249
+ V VC +G G SGMA+ +V LLSGF
Sbjct: 361 TPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALR 420
Query: 1250 --PSEAISLSET-VKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVD 1306
+ SLS+ V E + + LY DSV ++ CV AV+ V Q AS ++ D
Sbjct: 421 ADLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYD 480
Query: 1307 YYEPRRQAVRSYNSEVK------LSSCDLCSDVQGCRP 1338
YY P R+ Y + K L S ++C +G P
Sbjct: 481 YYNPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCP 518
>gi|169217711 PREDICTED: similar to Ovostatin homolog 2 [Homo
sapiens]
Length = 278
Score = 87.4 bits (215), Expect = 8e-17
Identities = 40/117 (34%), Positives = 71/117 (60%), Gaps = 1/117 (0%)
Query: 609 VRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAF 668
VR +FPETW+W ++ +PD+IT W A+GF ++ D+G G+++T L+
Sbjct: 67 VRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTT-LEVS 125
Query: 669 QPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINAT 725
QPFFI + P+SV++ E+F L + +F+Y E+ V +E+S ++ + + +IN +
Sbjct: 126 QPFFIEIASPFSVVQNEQFDLIVNVFSYRNTCVEISVQVEESQNYEANINTWKINGS 182
>gi|239755748 PREDICTED: ovostatin [Homo sapiens]
Length = 257
Score = 57.4 bits (137), Expect = 9e-08
Identities = 53/187 (28%), Positives = 79/187 (42%), Gaps = 27/187 (14%)
Query: 1143 FLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVVYNV----KASGSSRRRRSI 1198
F ++ HNRLL+Q +E+ P + G G Q + YNV KASG S +
Sbjct: 80 FQVNGHNRLLVQRSEVTQA-PGQYTVDVEGHGCTFIQATLKYNVLLPKKASGFSLSLEIV 138
Query: 1199 QNQE--AFDLDVAVKENKDDLNHVDLNVCTSFSG-PGRSGMALMEVNLLSGFMVPSEAIS 1255
+N AFDL V +K ++G +S M +++V +LSGF +I
Sbjct: 139 KNYSSTAFDLTVTLK----------------YTGIRNKSSMVVIDVKMLSGFTPTMSSIE 182
Query: 1256 LSET---VKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRR 1312
E V K E + + YL++ ++ V N Q A + DYYE
Sbjct: 183 ELENKGQVMKTEVKNDHVLFYLENGFGRADSFPFSVEQSNLVFNIQPAPAMVYDYYEKEE 242
Query: 1313 QAVRSYN 1319
A+ YN
Sbjct: 243 YALAFYN 249
>gi|169214179 PREDICTED: similar to complement component 3 [Homo
sapiens]
Length = 390
Score = 56.2 bits (134), Expect = 2e-07
Identities = 54/237 (22%), Positives = 101/237 (42%), Gaps = 29/237 (12%)
Query: 1124 ERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVV 1183
+ N+ V++ PS S + I + LL++ E + ++A G G + +
Sbjct: 17 QELNLDVSLQLPSRSSKITHRIHWESASLLRSEETK--ENEGFTVTAEGKGQGTLSVVTM 74
Query: 1184 YNVKASGSSRRRRSIQNQEAFDLDVAVK-------ENKDDLNHVDLNVCTSFSGPGRSGM 1236
Y+ KA + FDL V +K +D N + L +CT + G + M
Sbjct: 75 YHAKAKDQLTCNK-------FDLKVTIKPAPETEKRPQDAKNTMILEICTRYRGDQDATM 127
Query: 1237 ALMEVNLLSGFMVPSE-----AISLSETVKKVEY-----DHGKLNLYLDSVNETQ-FCVN 1285
+++++++++GF ++ A + + K E D L +YLD V+ ++ C+
Sbjct: 128 SILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVSHSEDDCLA 187
Query: 1286 IPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVKLSSCD-LCSDVQGCRPCED 1341
+ F V Q +V + YY R Y+ E + + LC D + CR E+
Sbjct: 188 FKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRD-ELCRCAEE 243
>gi|239754277 PREDICTED: similar to Complement component 4A (Rodgers
blood group) [Homo sapiens]
Length = 270
Score = 48.5 bits (114), Expect = 4e-05
Identities = 39/118 (33%), Positives = 58/118 (49%), Gaps = 13/118 (11%)
Query: 125 GDWSIQVQVNDQTYYQS---FQVSEYVLPKFEVTLQTP--LYCSMNSKHLNGT---ITAK 176
G W I + +D S F+V +YVLP FEV + TP Y HL+ I A+
Sbjct: 131 GTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKI-TPGKPYILTVPGHLDEMQLDIQAR 189
Query: 177 YTYGKPVKGDVTLTFLPLSFWGKKKNI----TKTFKINGSANFSFNDEEMKNVMDSSN 230
Y YGKPV+G + F L GKK ++T +NG ++ S + E ++ ++ N
Sbjct: 190 YIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKAEFQDALEKLN 247
>gi|169217713 PREDICTED: similar to Ovostatin homolog 2 [Homo sapiens]
Length = 189
Score = 46.6 bits (109), Expect = 2e-04
Identities = 37/135 (27%), Positives = 61/135 (45%), Gaps = 20/135 (14%)
Query: 991 VQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEAL-NMLTWRAEQEGGMQFWVS 1049
++ ++ LE+ G+++ Y A++ YA + G K E+L L A + + +W
Sbjct: 50 LRNALFCLEAALDSGVTNGYNHAILAYAFALAGKEKQVESLLQTLDQSATKLNNVIYWER 109
Query: 1050 SESKLSDS------WQPRSLDIEVAAYALLSHFLQFQTSEGIP-------IMRWLSRQRN 1096
++ W P S E + Y LL+ S IP I++WL++Q N
Sbjct: 110 ERKPKTEEFPSFIPWAP-SAQTEKSCYVLLAVI-----SRKIPDLTYASKIVQWLAQQMN 163
Query: 1097 SLGGFASTQDTTVAL 1111
S GGF+S Q V L
Sbjct: 164 SHGGFSSNQVINVGL 178
>gi|239752557 PREDICTED: similar to Ovostatin homolog 2 [Homo
sapiens]
Length = 261
Score = 46.6 bits (109), Expect = 2e-04
Identities = 26/94 (27%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
Query: 440 FSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSL 499
F L+ P A + VY + GEI++D ++ V FK+K+ + +S + P SL
Sbjct: 146 FPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQVDKCFKHKVNIKFSNEQGLPGSNASL 205
Query: 500 RISVTQPDSIVGIVAVDKSVNLMNASNDITMENV 533
+ P + AVD++V L+ + ++ E+V
Sbjct: 206 CLQAA-PVLFCALRAVDRNVLLLKSEQQLSAESV 238
>gi|225735595 RNA polymerase II associated protein 3 isoform 3 [Homo
sapiens]
Length = 506
Score = 34.7 bits (78), Expect = 0.64
Identities = 32/117 (27%), Positives = 50/117 (42%), Gaps = 6/117 (5%)
Query: 756 TVTALSPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGS 815
TV L P AVT++ +K E IEK + + LD T Q+ +K + P +
Sbjct: 216 TVLLLEPGNKQAVTELSKIKKELIEKGHWDDVFLDSTQR--QNVVKPIDNPPHPGSTKPL 273
Query: 816 ERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNL 872
++V I G+++ ++ P E N IN A I +KK D+L
Sbjct: 274 KKVIIEETGNLIQTIDVPDSTTAAAP----ENNPINLANVIAATGTTSKKNSSQDDL 326
>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
sapiens]
Length = 665
Score = 34.7 bits (78), Expect = 0.64
Identities = 32/117 (27%), Positives = 50/117 (42%), Gaps = 6/117 (5%)
Query: 756 TVTALSPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGS 815
TV L P AVT++ +K E IEK + + LD T Q+ +K + P +
Sbjct: 375 TVLLLEPGNKQAVTELSKIKKELIEKGHWDDVFLDSTQR--QNVVKPIDNPPHPGSTKPL 432
Query: 816 ERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNL 872
++V I G+++ ++ P E N IN A I +KK D+L
Sbjct: 433 KKVIIEETGNLIQTIDVPDSTTAAAP----ENNPINLANVIAATGTTSKKNSSQDDL 485
>gi|73695465 synaptic vesicle glycoprotein 2C [Homo sapiens]
Length = 727
Score = 33.1 bits (74), Expect = 1.9
Identities = 26/98 (26%), Positives = 44/98 (44%), Gaps = 15/98 (15%)
Query: 501 ISVTQPDSIVGIVAVDKSVNLMNASND--------ITMENVVHELELYNTGYYLGMFMNS 552
+SV PD I + + + ++ N D TMEN +H Y+ G ++G+ S
Sbjct: 450 LSVWFPDVIKPLQSDEYALLTRNVERDKYANFTINFTMENQIHTGMEYDNGRFIGVKFKS 509
Query: 553 F----AVFQECGLWVLTDANL---TKDYIDGVYDNAEY 583
+VF+ C +T N +ID V+DN ++
Sbjct: 510 VTFKDSVFKSCTFEDVTSVNTYFKNCTFIDTVFDNTDF 547
>gi|169205183 PREDICTED: similar to hCG38149 [Homo sapiens]
Length = 95
Score = 32.7 bits (73), Expect = 2.4
Identities = 24/87 (27%), Positives = 37/87 (42%), Gaps = 3/87 (3%)
Query: 1236 MALMEVNLLSGFMVPSEAISLSET---VKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNF 1292
M +++V +LSGF +I E V K E + + YL++ ++
Sbjct: 1 MVVIDVKMLSGFTPTMSSIEELENKGQVMKTEVKNDHVLFYLENGFGRADSFPFSVEQSN 60
Query: 1293 KVSNTQDASVSIVDYYEPRRQAVRSYN 1319
V N Q A + DYYE A+ YN
Sbjct: 61 LVFNIQPAPAMVYDYYEKEEYALAFYN 87
>gi|239744557 PREDICTED: hypothetical protein LOC728715 [Homo sapiens]
Length = 95
Score = 32.7 bits (73), Expect = 2.4
Identities = 24/87 (27%), Positives = 37/87 (42%), Gaps = 3/87 (3%)
Query: 1236 MALMEVNLLSGFMVPSEAISLSET---VKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNF 1292
M +++V +LSGF +I E V K E + + YL++ ++
Sbjct: 1 MVVIDVKMLSGFTPTMSSIEELENKGQVMKTEVKNDHVLFYLENGFGRADSFPFSVEQSN 60
Query: 1293 KVSNTQDASVSIVDYYEPRRQAVRSYN 1319
V N Q A + DYYE A+ YN
Sbjct: 61 LVFNIQPAPAMVYDYYEKEEYALAFYN 87
>gi|239752555 PREDICTED: similar to Ovostatin homolog 2 [Homo
sapiens]
Length = 195
Score = 31.2 bits (69), Expect = 7.1
Identities = 14/43 (32%), Positives = 23/43 (53%)
Query: 440 FSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKI 482
F L+ P A + VY + GEI++D ++ V FK+K+
Sbjct: 146 FPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQVDKCFKHKV 188
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,376,549
Number of Sequences: 37866
Number of extensions: 2138125
Number of successful extensions: 5012
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 4819
Number of HSP's gapped (non-prelim): 72
length of query: 1368
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1253
effective length of database: 13,892,928
effective search space: 17407838784
effective search space used: 17407838784
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.