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Search of human proteins with 226371669
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|226371669 discs large homolog 7 isoform b [Homo sapiens]
(842 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|226371669 discs large homolog 7 isoform b [Homo sapiens] 1668 0.0
gi|226371667 discs large homolog 7 isoform a [Homo sapiens] 1602 0.0
gi|109891938 disks large-associated protein 4 isoform c [Homo sa... 83 9e-16
gi|34335251 disks large-associated protein 4 isoform b [Homo sap... 83 9e-16
gi|34335253 disks large-associated protein 4 isoform a [Homo sap... 83 9e-16
gi|19923274 discs large homolog-associated protein 1 isoform alp... 81 4e-15
gi|51339031 discs large homolog-associated protein 1 isoform bet... 81 4e-15
gi|38202224 discs large-associated protein 2 [Homo sapiens] 80 1e-14
gi|122937233 discs, large (Drosophila) homolog-associated protei... 77 9e-14
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 45 2e-04
gi|237858668 hypothetical protein LOC123207 isoform d [Homo sapi... 45 3e-04
gi|104526627 triadin [Homo sapiens] 45 3e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 43 0.001
gi|20070262 TNF receptor-associated factor 3 interacting protein... 42 0.002
gi|15149467 caldesmon 1 isoform 3 [Homo sapiens] 42 0.003
gi|224494572 hypothetical protein LOC401082 [Homo sapiens] 41 0.005
gi|15149463 caldesmon 1 isoform 4 [Homo sapiens] 41 0.005
gi|62821790 leucine zipper protein 2 [Homo sapiens] 40 0.007
gi|4826657 caldesmon 1 isoform 2 [Homo sapiens] 40 0.007
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 40 0.007
gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 ... 40 0.007
gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 ... 40 0.007
gi|15149465 caldesmon 1 isoform 5 [Homo sapiens] 40 0.012
gi|28212280 hypothetical protein LOC283579 [Homo sapiens] 40 0.012
gi|116174778 centrosome spindle pole associated protein 1 isofor... 39 0.015
gi|116174789 centrosome spindle pole associated protein 1 isofor... 39 0.015
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 39 0.020
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 39 0.020
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 39 0.020
gi|57529246 ubiquitin thioesterase 19 [Homo sapiens] 39 0.026
>gi|226371669 discs large homolog 7 isoform b [Homo sapiens]
Length = 842
Score = 1668 bits (4319), Expect = 0.0
Identities = 842/842 (100%), Positives = 842/842 (100%)
Query: 1 MSSSHFASRHRKDISTEMIRTKIAHRKSLSQKENRHKEYERNRHFGLKDVNIPTLEGRIL 60
MSSSHFASRHRKDISTEMIRTKIAHRKSLSQKENRHKEYERNRHFGLKDVNIPTLEGRIL
Sbjct: 1 MSSSHFASRHRKDISTEMIRTKIAHRKSLSQKENRHKEYERNRHFGLKDVNIPTLEGRIL 60
Query: 61 VELDETSQGLVPEKTNVKPRAMKTILGDQRKQMLQKYKEEKQLQKLKEQREKAKRGIFKV 120
VELDETSQGLVPEKTNVKPRAMKTILGDQRKQMLQKYKEEKQLQKLKEQREKAKRGIFKV
Sbjct: 61 VELDETSQGLVPEKTNVKPRAMKTILGDQRKQMLQKYKEEKQLQKLKEQREKAKRGIFKV 120
Query: 121 GRYRPDMPCFLLSNQNAVKAEPKKAIPSSVRITRSKAKDQMEQTKIDNESDVRAIRPGPR 180
GRYRPDMPCFLLSNQNAVKAEPKKAIPSSVRITRSKAKDQMEQTKIDNESDVRAIRPGPR
Sbjct: 121 GRYRPDMPCFLLSNQNAVKAEPKKAIPSSVRITRSKAKDQMEQTKIDNESDVRAIRPGPR 180
Query: 181 QTSEKKVSDKEKKVVQPVMPTSLRMTRSATQAAKQVPRTVSSTTARKPVTRAANENEPEG 240
QTSEKKVSDKEKKVVQPVMPTSLRMTRSATQAAKQVPRTVSSTTARKPVTRAANENEPEG
Sbjct: 181 QTSEKKVSDKEKKVVQPVMPTSLRMTRSATQAAKQVPRTVSSTTARKPVTRAANENEPEG 240
Query: 241 KVPSKGRPAKNVETKPDKGISCKVDSEENTLNSQTNATSGMNPDGVLSKMENLPEINTAK 300
KVPSKGRPAKNVETKPDKGISCKVDSEENTLNSQTNATSGMNPDGVLSKMENLPEINTAK
Sbjct: 241 KVPSKGRPAKNVETKPDKGISCKVDSEENTLNSQTNATSGMNPDGVLSKMENLPEINTAK 300
Query: 301 IKGKNSFAPKDFMFQPLDGLKTYQVTPMTPRSANAFLTPSYTWTPLKTEVDESQATKEIL 360
IKGKNSFAPKDFMFQPLDGLKTYQVTPMTPRSANAFLTPSYTWTPLKTEVDESQATKEIL
Sbjct: 301 IKGKNSFAPKDFMFQPLDGLKTYQVTPMTPRSANAFLTPSYTWTPLKTEVDESQATKEIL 360
Query: 361 AQKCKTYSTKTIQQDSNKLPCPLGPLTVWHEEHVLNKNEATTKNLNGLPIKEVPSLERNE 420
AQKCKTYSTKTIQQDSNKLPCPLGPLTVWHEEHVLNKNEATTKNLNGLPIKEVPSLERNE
Sbjct: 361 AQKCKTYSTKTIQQDSNKLPCPLGPLTVWHEEHVLNKNEATTKNLNGLPIKEVPSLERNE 420
Query: 421 GRIAQPHHGVPYFRNILQSETEKLTSHCFEWDRKLELDIPDDAKDLIRTAVGQTRLLMKE 480
GRIAQPHHGVPYFRNILQSETEKLTSHCFEWDRKLELDIPDDAKDLIRTAVGQTRLLMKE
Sbjct: 421 GRIAQPHHGVPYFRNILQSETEKLTSHCFEWDRKLELDIPDDAKDLIRTAVGQTRLLMKE 480
Query: 481 RFKQFEGLVDDCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQVNNN 540
RFKQFEGLVDDCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQVNNN
Sbjct: 481 RFKQFEGLVDDCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQVNNN 540
Query: 541 MNHNMNKNVFRKKVVSGIASKPKQDDAGRIAARNRLAAIKNAMRERIRQEECAETAVSVI 600
MNHNMNKNVFRKKVVSGIASKPKQDDAGRIAARNRLAAIKNAMRERIRQEECAETAVSVI
Sbjct: 541 MNHNMNKNVFRKKVVSGIASKPKQDDAGRIAARNRLAAIKNAMRERIRQEECAETAVSVI 600
Query: 601 PKEVDKIVFDAGFFRVESPVKLFSGLSVSSEGPSQRLGTPKSVNKAVSQSRNEMGIPQQT 660
PKEVDKIVFDAGFFRVESPVKLFSGLSVSSEGPSQRLGTPKSVNKAVSQSRNEMGIPQQT
Sbjct: 601 PKEVDKIVFDAGFFRVESPVKLFSGLSVSSEGPSQRLGTPKSVNKAVSQSRNEMGIPQQT 660
Query: 661 TSPENAGPQNTKSEHVKKTLFLSIPESRSSIEDAQCPGLPDLIEENHVVNKTDLKVDCLS 720
TSPENAGPQNTKSEHVKKTLFLSIPESRSSIEDAQCPGLPDLIEENHVVNKTDLKVDCLS
Sbjct: 661 TSPENAGPQNTKSEHVKKTLFLSIPESRSSIEDAQCPGLPDLIEENHVVNKTDLKVDCLS 720
Query: 721 SERMSLPLLAGGVADDINTNKKEGISDVVEGMELNSSITSQDVLMSSPEKNTASQNSILE 780
SERMSLPLLAGGVADDINTNKKEGISDVVEGMELNSSITSQDVLMSSPEKNTASQNSILE
Sbjct: 721 SERMSLPLLAGGVADDINTNKKEGISDVVEGMELNSSITSQDVLMSSPEKNTASQNSILE 780
Query: 781 EGETKISQSELFDNKSLTTECHLLDSVGSCYVARAGLEVLGSSDPTTSASRVAGTTARSK 840
EGETKISQSELFDNKSLTTECHLLDSVGSCYVARAGLEVLGSSDPTTSASRVAGTTARSK
Sbjct: 781 EGETKISQSELFDNKSLTTECHLLDSVGSCYVARAGLEVLGSSDPTTSASRVAGTTARSK 840
Query: 841 LQ 842
LQ
Sbjct: 841 LQ 842
>gi|226371667 discs large homolog 7 isoform a [Homo sapiens]
Length = 846
Score = 1602 bits (4148), Expect = 0.0
Identities = 807/808 (99%), Positives = 807/808 (99%)
Query: 1 MSSSHFASRHRKDISTEMIRTKIAHRKSLSQKENRHKEYERNRHFGLKDVNIPTLEGRIL 60
MSSSHFASRHRKDISTEMIRTKIAHRKSLSQKENRHKEYERNRHFGLKDVNIPTLEGRIL
Sbjct: 1 MSSSHFASRHRKDISTEMIRTKIAHRKSLSQKENRHKEYERNRHFGLKDVNIPTLEGRIL 60
Query: 61 VELDETSQGLVPEKTNVKPRAMKTILGDQRKQMLQKYKEEKQLQKLKEQREKAKRGIFKV 120
VELDETSQGLVPEKTNVKPRAMKTILGDQRKQMLQKYKEEKQLQKLKEQREKAKRGIFKV
Sbjct: 61 VELDETSQGLVPEKTNVKPRAMKTILGDQRKQMLQKYKEEKQLQKLKEQREKAKRGIFKV 120
Query: 121 GRYRPDMPCFLLSNQNAVKAEPKKAIPSSVRITRSKAKDQMEQTKIDNESDVRAIRPGPR 180
GRYRPDMPCFLLSNQNAVKAEPKKAIPSSVRITRSKAKDQMEQTKIDNESDVRAIRPGPR
Sbjct: 121 GRYRPDMPCFLLSNQNAVKAEPKKAIPSSVRITRSKAKDQMEQTKIDNESDVRAIRPGPR 180
Query: 181 QTSEKKVSDKEKKVVQPVMPTSLRMTRSATQAAKQVPRTVSSTTARKPVTRAANENEPEG 240
QTSEKKVSDKEKKVVQPVMPTSLRMTRSATQAAKQVPRTVSSTTARKPVTRAANENEPEG
Sbjct: 181 QTSEKKVSDKEKKVVQPVMPTSLRMTRSATQAAKQVPRTVSSTTARKPVTRAANENEPEG 240
Query: 241 KVPSKGRPAKNVETKPDKGISCKVDSEENTLNSQTNATSGMNPDGVLSKMENLPEINTAK 300
KVPSKGRPAKNVETKPDKGISCKVDSEENTLNSQTNATSGMNPDGVLSKMENLPEINTAK
Sbjct: 241 KVPSKGRPAKNVETKPDKGISCKVDSEENTLNSQTNATSGMNPDGVLSKMENLPEINTAK 300
Query: 301 IKGKNSFAPKDFMFQPLDGLKTYQVTPMTPRSANAFLTPSYTWTPLKTEVDESQATKEIL 360
IKGKNSFAPKDFMFQPLDGLKTYQVTPMTPRSANAFLTPSYTWTPLKTEVDESQATKEIL
Sbjct: 301 IKGKNSFAPKDFMFQPLDGLKTYQVTPMTPRSANAFLTPSYTWTPLKTEVDESQATKEIL 360
Query: 361 AQKCKTYSTKTIQQDSNKLPCPLGPLTVWHEEHVLNKNEATTKNLNGLPIKEVPSLERNE 420
AQKCKTYSTKTIQQDSNKLPCPLGPLTVWHEEHVLNKNEATTKNLNGLPIKEVPSLERNE
Sbjct: 361 AQKCKTYSTKTIQQDSNKLPCPLGPLTVWHEEHVLNKNEATTKNLNGLPIKEVPSLERNE 420
Query: 421 GRIAQPHHGVPYFRNILQSETEKLTSHCFEWDRKLELDIPDDAKDLIRTAVGQTRLLMKE 480
GRIAQPHHGVPYFRNILQSETEKLTSHCFEWDRKLELDIPDDAKDLIRTAVGQTRLLMKE
Sbjct: 421 GRIAQPHHGVPYFRNILQSETEKLTSHCFEWDRKLELDIPDDAKDLIRTAVGQTRLLMKE 480
Query: 481 RFKQFEGLVDDCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQVNNN 540
RFKQFEGLVDDCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQVNNN
Sbjct: 481 RFKQFEGLVDDCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQVNNN 540
Query: 541 MNHNMNKNVFRKKVVSGIASKPKQDDAGRIAARNRLAAIKNAMRERIRQEECAETAVSVI 600
MNHNMNKNVFRKKVVSGIASKPKQDDAGRIAARNRLAAIKNAMRERIRQEECAETAVSVI
Sbjct: 541 MNHNMNKNVFRKKVVSGIASKPKQDDAGRIAARNRLAAIKNAMRERIRQEECAETAVSVI 600
Query: 601 PKEVDKIVFDAGFFRVESPVKLFSGLSVSSEGPSQRLGTPKSVNKAVSQSRNEMGIPQQT 660
PKEVDKIVFDAGFFRVESPVKLFSGLSVSSEGPSQRLGTPKSVNKAVSQSRNEMGIPQQT
Sbjct: 601 PKEVDKIVFDAGFFRVESPVKLFSGLSVSSEGPSQRLGTPKSVNKAVSQSRNEMGIPQQT 660
Query: 661 TSPENAGPQNTKSEHVKKTLFLSIPESRSSIEDAQCPGLPDLIEENHVVNKTDLKVDCLS 720
TSPENAGPQNTKSEHVKKTLFLSIPESRSSIEDAQCPGLPDLIEENHVVNKTDLKVDCLS
Sbjct: 661 TSPENAGPQNTKSEHVKKTLFLSIPESRSSIEDAQCPGLPDLIEENHVVNKTDLKVDCLS 720
Query: 721 SERMSLPLLAGGVADDINTNKKEGISDVVEGMELNSSITSQDVLMSSPEKNTASQNSILE 780
SERMSLPLLAGGVADDINTNKKEGISDVVEGMELNSSITSQDVLMSSPEKNTASQNSILE
Sbjct: 721 SERMSLPLLAGGVADDINTNKKEGISDVVEGMELNSSITSQDVLMSSPEKNTASQNSILE 780
Query: 781 EGETKISQSELFDNKSLTTECHLLDSVG 808
EGETKISQSELFDNKSLTTECHLLDS G
Sbjct: 781 EGETKISQSELFDNKSLTTECHLLDSPG 808
>gi|109891938 disks large-associated protein 4 isoform c [Homo
sapiens]
Length = 285
Score = 83.2 bits (204), Expect = 9e-16
Identities = 58/178 (32%), Positives = 89/178 (50%), Gaps = 12/178 (6%)
Query: 432 YFRNILQSETEKLTSHCFEWDRKL-ELDIPDDAKDLIRTAVGQTRLLMKERFKQFEGLVD 490
+F +LQ+ETE+L C + D++ E ++ ++ + +AVG +LLM ++F+QF GL +
Sbjct: 99 WFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCE 158
Query: 491 DCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQVNNNMNHNMNKN-- 548
T DL GFWD++ IED+ KF+ L L+ + WQ+ +
Sbjct: 159 QNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKP 218
Query: 549 ---VFRKKVVSGIA-SKPKQDDAG---RIAARNRLAAIKNAMRERIRQEECAETAVSV 599
V +K S A S+ K DA R AR RL A K A +RQ E+A S+
Sbjct: 219 PPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRA--ASVRQNSATESADSI 274
>gi|34335251 disks large-associated protein 4 isoform b [Homo
sapiens]
Length = 453
Score = 83.2 bits (204), Expect = 9e-16
Identities = 58/178 (32%), Positives = 89/178 (50%), Gaps = 12/178 (6%)
Query: 432 YFRNILQSETEKLTSHCFEWDRKL-ELDIPDDAKDLIRTAVGQTRLLMKERFKQFEGLVD 490
+F +LQ+ETE+L C + D++ E ++ ++ + +AVG +LLM ++F+QF GL +
Sbjct: 267 WFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCE 326
Query: 491 DCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQVNNNMNHNMNKN-- 548
T DL GFWD++ IED+ KF+ L L+ + WQ+ +
Sbjct: 327 QNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKP 386
Query: 549 ---VFRKKVVSGIA-SKPKQDDAG---RIAARNRLAAIKNAMRERIRQEECAETAVSV 599
V +K S A S+ K DA R AR RL A K A +RQ E+A S+
Sbjct: 387 PPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRA--ASVRQNSATESADSI 442
>gi|34335253 disks large-associated protein 4 isoform a [Homo
sapiens]
Length = 989
Score = 83.2 bits (204), Expect = 9e-16
Identities = 58/178 (32%), Positives = 89/178 (50%), Gaps = 12/178 (6%)
Query: 432 YFRNILQSETEKLTSHCFEWDRKL-ELDIPDDAKDLIRTAVGQTRLLMKERFKQFEGLVD 490
+F +LQ+ETE+L C + D++ E ++ ++ + +AVG +LLM ++F+QF GL +
Sbjct: 803 WFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCE 862
Query: 491 DCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQVNNNMNHNMNKN-- 548
T DL GFWD++ IED+ KF+ L L+ + WQ+ +
Sbjct: 863 QNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKP 922
Query: 549 ---VFRKKVVSGIA-SKPKQDDAG---RIAARNRLAAIKNAMRERIRQEECAETAVSV 599
V +K S A S+ K DA R AR RL A K A +RQ E+A S+
Sbjct: 923 PPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRA--ASVRQNSATESADSI 978
>gi|19923274 discs large homolog-associated protein 1 isoform alpha
[Homo sapiens]
Length = 977
Score = 81.3 bits (199), Expect = 4e-15
Identities = 55/179 (30%), Positives = 91/179 (50%), Gaps = 8/179 (4%)
Query: 427 HHGVPYFRNILQSETEKLTSHCFEWDRK-LELDIPDDAKDLIRTAVGQTRLLMKERFKQF 485
H +F +LQ+E +++ C + +R+ E ++P+D IRTAVG +LLM ++F QF
Sbjct: 790 HRDGHWFLKLLQAERDRMEGWCQQMEREERENNLPEDILGKIRTAVGSAQLLMAQKFYQF 849
Query: 486 EGLVDDCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQVNNNMNHNM 545
L ++ T DL GFWDM+ IE++ KF+ L +L+ + W+ + ++
Sbjct: 850 RELCEENLNPNAHPRPTSQDLAGFWDMLQLSIENISMKFDELHQLKANNWKQMDPLDKKE 909
Query: 546 NK--NVFRKKVVSGIASKPKQ---DDAGRIAARNRLAAIKNAMRERIRQEECAETAVSV 599
+ KK G A ++ + + R AR RL A K A +RQ E+A S+
Sbjct: 910 RRAPPPVPKKPAKGPAPLIRERSLESSQRQEARKRLMAAKRA--ASVRQNSATESAESI 966
>gi|51339031 discs large homolog-associated protein 1 isoform beta
[Homo sapiens]
Length = 675
Score = 81.3 bits (199), Expect = 4e-15
Identities = 55/179 (30%), Positives = 91/179 (50%), Gaps = 8/179 (4%)
Query: 427 HHGVPYFRNILQSETEKLTSHCFEWDRK-LELDIPDDAKDLIRTAVGQTRLLMKERFKQF 485
H +F +LQ+E +++ C + +R+ E ++P+D IRTAVG +LLM ++F QF
Sbjct: 488 HRDGHWFLKLLQAERDRMEGWCQQMEREERENNLPEDILGKIRTAVGSAQLLMAQKFYQF 547
Query: 486 EGLVDDCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQVNNNMNHNM 545
L ++ T DL GFWDM+ IE++ KF+ L +L+ + W+ + ++
Sbjct: 548 RELCEENLNPNAHPRPTSQDLAGFWDMLQLSIENISMKFDELHQLKANNWKQMDPLDKKE 607
Query: 546 NK--NVFRKKVVSGIASKPKQ---DDAGRIAARNRLAAIKNAMRERIRQEECAETAVSV 599
+ KK G A ++ + + R AR RL A K A +RQ E+A S+
Sbjct: 608 RRAPPPVPKKPAKGPAPLIRERSLESSQRQEARKRLMAAKRA--ASVRQNSATESAESI 664
>gi|38202224 discs large-associated protein 2 [Homo sapiens]
Length = 975
Score = 79.7 bits (195), Expect = 1e-14
Identities = 61/196 (31%), Positives = 95/196 (48%), Gaps = 12/196 (6%)
Query: 414 PSLERNE-GRIAQPHHGVPYFRNILQSETEKLTSHCFEWDRKLEL-DIPDDAKDLIRTAV 471
P+++ E GR++ +F +L +ET+++ C E +R+ E D+ ++ IR+AV
Sbjct: 771 PAIDTVETGRMSPCRRDGSWFLKLLHAETKRMEGWCKEMEREAEENDLSEEILGKIRSAV 830
Query: 472 GQTRLLMKERFKQFEGLVDDCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLE 531
G +LLM ++F+QF L + T DL G+WDM+ IEDV KF+ L +L
Sbjct: 831 GSAQLLMSQKFQQFYWLCQQNMDPSAMPRPTSQDLAGYWDMLQLSIEDVSMKFDELQRLR 890
Query: 532 ESGWQVNNNMNHNMNKNV---FRKKVVSG---IASKPKQD--DAGRIAARNRLAAIKNAM 583
+ W++ + + V KK G I + D D R AR RL A K A
Sbjct: 891 LNDWKMMESPERKEERKVPPPIPKKPPKGKFPITREKSLDLPDRQRQEARRRLMAAKRA- 949
Query: 584 RERIRQEECAETAVSV 599
RQ +E A S+
Sbjct: 950 -ASFRQNSASERADSI 964
>gi|122937233 discs, large (Drosophila) homolog-associated protein 3
[Homo sapiens]
Length = 979
Score = 76.6 bits (187), Expect = 9e-14
Identities = 56/187 (29%), Positives = 87/187 (46%), Gaps = 8/187 (4%)
Query: 419 NEGRIAQPHHGVPYFRNILQSETEKLTSHCFEWDRKLE-LDIPDDAKDLIRTAVGQTRLL 477
+ GR + +F +L++E EKL C + +R+ E ++P++ + IR+AVG T+LL
Sbjct: 784 DSGRASPCPRDGEWFIKMLRAEVEKLEHWCQQMEREAEDYELPEEILEKIRSAVGSTQLL 843
Query: 478 MKERFKQFEGLVDDCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQV 537
+ ++ +QF L T DL GFWD++ IEDV KF L +L+ + W++
Sbjct: 844 LSQKVQQFFRLCQQSMDPTAFPVPTFQDLAGFWDLLQLSIEDVTLKFLELQQLKANSWKL 903
Query: 538 NNNMNHNMNKNVFRKKVVSGIASKPKQD-----DAGRIAARNRLAAIKNAMRERIRQEEC 592
KK + G K+ D R AR RL A K A R
Sbjct: 904 LEPKEEKKVPPPIPKKPLRGRGVPVKERSLDSVDRQRQEARKRLLAAKRA--ASFRHSSA 961
Query: 593 AETAVSV 599
E+A S+
Sbjct: 962 TESADSI 968
>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
Length = 2089
Score = 45.4 bits (106), Expect = 2e-04
Identities = 41/161 (25%), Positives = 73/161 (45%), Gaps = 19/161 (11%)
Query: 134 NQNAVKAEPKKAIPSSVRITRSKAKDQMEQTKIDNESDVRAIRPGPRQTSEKKVSDKEKK 193
N+++VK P+ +P++ + S + DQ + +E +A R ++S K
Sbjct: 1233 NRSSVKT-PEPVVPTAPELQPSTSTDQ----PVTSEPTYQATRGRKNRSSVK-------- 1279
Query: 194 VVQPVMPTSLRMTRSATQAAKQVPRTVSSTTARKPVTRAANENEPEGKVPSKGRPAKNVE 253
+PV+PT+ + S + P+ S TT + T ++ PE VP+ P +
Sbjct: 1280 TPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSR--TNMSSVKTPETVVPT--APELQIS 1335
Query: 254 TKPDKGISCKVDSEENTLNSQTNATSGMNPDGVLSKMENLP 294
T D+ ++ K S T S+TN +S NP+ + LP
Sbjct: 1336 TSTDQPVTPKPTS--RTTRSRTNMSSVKNPESTVPIAPELP 1374
>gi|237858668 hypothetical protein LOC123207 isoform d [Homo
sapiens]
Length = 167
Score = 45.1 bits (105), Expect = 3e-04
Identities = 22/37 (59%), Positives = 27/37 (72%)
Query: 803 LLDSVGSCYVARAGLEVLGSSDPTTSASRVAGTTARS 839
+LD GSCY+A+AGLE+L SSD SAS+ AG T S
Sbjct: 119 VLDKTGSCYIAQAGLELLASSDLPASASQSAGITGVS 155
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 45.1 bits (105), Expect = 3e-04
Identities = 50/251 (19%), Positives = 102/251 (40%), Gaps = 25/251 (9%)
Query: 22 KIAHRKSLSQKENRHKEYERNRHFGLKDVNIPTLEGRILVELDETSQGLVPEKTNVKPRA 81
K A +K S+ + + KE + + E I VE E + ++ VK A
Sbjct: 317 KKAEKKVTSETKKKEKEDIKKKS---------EKETAIDVEKKEPGKASETKQGTVKIAA 367
Query: 82 MKTILGDQRKQMLQKYKEEKQLQKLKEQREKAKRGIFKVGRYRPDMPCFLLSNQNAVKAE 141
D++K+ +K K+ ++++ K ++++ K + + Q K E
Sbjct: 368 QAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTE 427
Query: 142 PKKAIPSSVRITRSKAKDQMEQTKIDNESDVRAIRPGPRQT---SEKKVSDKEKKVVQPV 198
K +V I ++ + E+T E ++R + G + ++ + KE+KV
Sbjct: 428 RAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKV---- 483
Query: 199 MPTSLRMTRSATQAAKQVPRTVSSTTARKPVTRAANENEPEGKVPSKGRPA--------K 250
P SL+ T+ +++ + + P + E +PE ++ + +PA K
Sbjct: 484 -PASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHK 542
Query: 251 NVETKPDKGIS 261
KP+K +S
Sbjct: 543 QDIVKPEKTVS 553
Score = 38.9 bits (89), Expect = 0.020
Identities = 70/338 (20%), Positives = 127/338 (37%), Gaps = 40/338 (11%)
Query: 5 HFASRHRKDISTEMIRTKIAHRKSLSQKENRHKEYERNRHFGLKDVNIPTLEGRILVELD 64
H +++ I+TK+ H++ KE ++ + + K+ +
Sbjct: 144 HKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTLAK 203
Query: 65 ETSQGLVPEKTNVKPRAMKTILGDQRKQMLQKYKEEKQLQKL------KEQREKA----- 113
E + EK+ K + K + G +++++ Q + K++QK KE +EKA
Sbjct: 204 EQKKAKTAEKSEEKTK--KEVKGGKQEKVKQTAAKVKEVQKTPSKPKEKEDKEKAAVSKH 261
Query: 114 -KRGIFKVGRYRPDMPCF--LLSNQNAVKAEP------KKAIPSSVRITRSKAKDQMEQT 164
++ + RY D+ L Q+ P + P+S + + + + +
Sbjct: 262 EQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTPASPALEEKEGEKKKAEK 321
Query: 165 KIDNESDVRAIRPGPRQTSEKKVSDKEKKVVQPVMPTSLRMTRSATQ-AAKQVPRTVSST 223
K+ +E+ + +++ ++ D EKK T + A Q AAK+ + S
Sbjct: 322 KVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSK 381
Query: 224 TARKPVTRAANENEPEGKVPSKGR--------PAKNVETKPDKGISCKVD--SEENTLNS 273
+KP A +P+GK K P K DK + K + EE S
Sbjct: 382 KTKKP----AEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVS 437
Query: 274 QTNATSGMNPDGVLSKMENLPEINTAKIKGKNSFAPKD 311
A G + +E EI K GK S KD
Sbjct: 438 IKKAVPGKKEEKTTKTVEQ--EIRKEK-SGKTSSILKD 472
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 43.1 bits (100), Expect = 0.001
Identities = 51/206 (24%), Positives = 84/206 (40%), Gaps = 19/206 (9%)
Query: 580 KNAMRERIRQEECAETAVSVIPKEVDKIVFDAGFFRVESPVKLFSGLSVSSEGPSQRLGT 639
K+ +E + E A++ V K +K +SP K S + ++ P +
Sbjct: 653 KSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKA-EAKSPEKAKSPVKEEAKSPEKAKSP 711
Query: 640 ----PKSVNKAVSQSRNEMGIPQQTTSP---ENAGPQNTKSEHVKKTLFLSIPESRS-SI 691
KS KA S + E P++ SP E P+ KS KTL + PE+++ +
Sbjct: 712 VKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAK 771
Query: 692 EDAQCPGLPDLIEENHVVNKTDLKVDCLSSERMSLPLLAGGVADDINTNKKEGISDVVEG 751
E+A+ P D E K+ +K + S E+ PL A + KKE + V+
Sbjct: 772 EEARSPA--DKFPEK---AKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKE 826
Query: 752 MELNSSITSQDVLMSSPEKNTASQNS 777
E Q+V + P K + +
Sbjct: 827 EE-----KPQEVKVKEPPKKAEEEKA 847
Score = 39.3 bits (90), Expect = 0.015
Identities = 50/248 (20%), Positives = 99/248 (39%), Gaps = 24/248 (9%)
Query: 72 PEKT---NVKPRAMKTILGDQRKQMLQKYKEEKQLQKLKEQR--EKAKRGIFKVGRYRPD 126
PEK +VK KT ++ + K+ E+ + +E + EKAK + K P+
Sbjct: 753 PEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPL-KEDAKAPE 811
Query: 127 MPCFLLSNQNAVKAEPKKAI-PSSVRITRSKAKDQMEQT----KIDNESDVRAIRPGPRQ 181
+ + VK+ K+ P V++ K + E+ K + + D + ++
Sbjct: 812 KE---IPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKE 868
Query: 182 TSEKKVSDKEKKVVQPVMPTSLRMTRSATQAAKQVPRTVSSTTAR---------KPVTRA 232
+ KV +K++ V+ + + + + K+VP A+ K T
Sbjct: 869 APKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEV 928
Query: 233 ANENEPEGKVPSKGRPAKNVETKPDKGISCKVDSEENTLNSQTNATSGMNPDGVLSKMEN 292
A + + K +PA+ E P+K + + +++ +T A D LSK +
Sbjct: 929 AKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEA-KAKEDDKTLSKEPS 987
Query: 293 LPEINTAK 300
P+ A+
Sbjct: 988 KPKAEKAE 995
>gi|20070262 TNF receptor-associated factor 3 interacting protein 1
isoform 1 [Homo sapiens]
Length = 691
Score = 42.0 bits (97), Expect = 0.002
Identities = 55/282 (19%), Positives = 106/282 (37%), Gaps = 28/282 (9%)
Query: 47 LKDVNIPTLEGRILVELDETSQGLVPEKTNVKPRAMKTILGDQRKQMLQKYKEEKQLQKL 106
L + N+ E R+ ++ + E++ + R K L + RK +++K +K
Sbjct: 149 LDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPR----EKDKDKEKA 204
Query: 107 KE---------QREKAKRGIFKVGRYRPDMPCFLLSNQNAVKAEPKKAIPSSVRITRSKA 157
KE +RE+AK + D + K E ++ R +
Sbjct: 205 KENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRD 264
Query: 158 KDQMEQTKIDNESDVRAIRPGPRQ----TSEKKVSDKEKKVVQPVMPTSLRMTRSATQAA 213
+D+ + D R ++ G + + DK +K S +++ + +
Sbjct: 265 RDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDS 324
Query: 214 KQVPRTVSSTTARKPVTRAANENEPEGKVPSKGRPAKNVETKPDKGISCKVDSEEN---- 269
K T ST A K +T ++ + V +GR N+ K I +++E N
Sbjct: 325 KAETETEISTRASKSLTTKTSKRRSKNSV--EGRKEDNISAKSLDSIVSGINNEPNQETT 382
Query: 270 -----TLNSQTNATSGMNPDGVLSKMENLPEINTAKIKGKNS 306
T + N+TS + + + EN+ T K KG ++
Sbjct: 383 TSEIGTKEANINSTSISDDNSASLRCENIQPNPTEKQKGDST 424
>gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]
Length = 564
Score = 41.6 bits (96), Expect = 0.003
Identities = 52/272 (19%), Positives = 110/272 (40%), Gaps = 8/272 (2%)
Query: 9 RHRKDISTEMIRTKIAHRKSLSQKENRHKEYERN-RHFGLKDVNIPTLEGRILVELDETS 67
R +K + +IA++++ +E +E R R L+ G++ +++ +
Sbjct: 11 RRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNA 70
Query: 68 QGLVPEKTNVKPRAMKTILGDQRKQMLQKY--KEEKQLQKLKEQREKAKRGIFKVGRYRP 125
Q VP++ + GD L++ +EE++ ++L+E E+ K +
Sbjct: 71 QNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASL 130
Query: 126 DMPCFLLSNQNAVKAEPKKAIPSSVRITRSKAKDQMEQTKIDNESDVRAIRPGPRQTSEK 185
+P + N A +K S R R + ++ TK ++D R ++ EK
Sbjct: 131 SLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEK 190
Query: 186 KVSDKEKKVVQPVMPTSLRMTRSATQAAKQVPRTVSSTTARKPV--TRAANENEPEGKVP 243
+ ++EK + + QA ++ + T ++ + + + EP+ +V
Sbjct: 191 EEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVK 250
Query: 244 S-KGRPAKNVETKPDKG--ISCKVDSEENTLN 272
S R E K G ++ K+ ENT +
Sbjct: 251 SFMDRKKGFTEVKSQNGEFMTHKLKHTENTFS 282
>gi|224494572 hypothetical protein LOC401082 [Homo sapiens]
Length = 95
Score = 40.8 bits (94), Expect = 0.005
Identities = 23/35 (65%), Positives = 27/35 (77%), Gaps = 2/35 (5%)
Query: 802 HLLDSVGSCYVARAGLEVLGSSDPTTSASRVAGTT 836
HL D GS YVA+AGLE+LGSS+ TSA + AGTT
Sbjct: 12 HLED--GSHYVAQAGLELLGSSNSPTSAYQAAGTT 44
>gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]
Length = 558
Score = 40.8 bits (94), Expect = 0.005
Identities = 50/260 (19%), Positives = 107/260 (41%), Gaps = 8/260 (3%)
Query: 21 TKIAHRKSLSQKENRHKEYERN-RHFGLKDVNIPTLEGRILVELDETSQGLVPEKTNVKP 79
++IA++++ +E +E R R L+ G++ +++ +Q VP++
Sbjct: 17 SQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTT 76
Query: 80 RAMKTILGDQRKQMLQKY--KEEKQLQKLKEQREKAKRGIFKVGRYRPDMPCFLLSNQNA 137
+ GD L++ +EE++ ++L+E E+ K + +P + N A
Sbjct: 77 TTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTA 136
Query: 138 VKAEPKKAIPSSVRITRSKAKDQMEQTKIDNESDVRAIRPGPRQTSEKKVSDKEKKVVQP 197
+K S R R + ++ TK ++D R ++ EK+ ++EK
Sbjct: 137 ENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGS 196
Query: 198 VMPTSLRMTRSATQAAKQVPRTVSSTTARKPV--TRAANENEPEGKVPS-KGRPAKNVET 254
+ + QA ++ + T ++ + + + EP+ +V S R E
Sbjct: 197 IGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV 256
Query: 255 KPDKG--ISCKVDSEENTLN 272
K G ++ K+ ENT +
Sbjct: 257 KSQNGEFMTHKLKHTENTFS 276
>gi|62821790 leucine zipper protein 2 [Homo sapiens]
Length = 346
Score = 40.4 bits (93), Expect = 0.007
Identities = 69/330 (20%), Positives = 127/330 (38%), Gaps = 57/330 (17%)
Query: 23 IAHRKSLSQKENRHKEYERNRHFGLKDVNIPTLEGRILVELDETSQGLVPEKTNVKPRAM 82
++ R+ + E + KE + R L+ + T R L + Q L ++ + K
Sbjct: 18 LSTRQDYEELEKQLKEVFKERSTILRQL---TKTSRELDGIKVNLQSLKNDEQSAKTDVQ 74
Query: 83 KTI-LGDQRKQMLQKYKEEKQLQKLKEQREKAKR-----GIFKVGRYRPDMPCFLLSNQN 136
K + LG ++++ ++ +E Q Q LKE EKA++ K R L N+N
Sbjct: 75 KLLELGQKQREEMKSLQEALQNQ-LKETSEKAEKHQATINFLKTEVERKSKMIRDLQNEN 133
Query: 137 --------------AVKAEPKKAIPSSVRITR--------------------SKAKDQME 162
+ AE K I + ++ R + AK+++E
Sbjct: 134 KSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELE 193
Query: 163 QTKIDNESDVRAIRPGPRQTSEKKVSDKEKKVVQPVMPTSLRMTRSATQAAKQVPRTVSS 222
+ +D ES ++A++ + D+ + + RM A ++P +
Sbjct: 194 KAALDRESQMKAMKETVQLCLTSVFRDQPPPPLSLITSNPTRMLLPPRNIASKLPDAAAK 253
Query: 223 TTARKPVTRAANENEPEGKVPSK-GRPAKNVETKPDKGISCKVDSEENTLNSQTNATSGM 281
+ KP A+ NE +K G P+ D+G C + +E + +NAT+
Sbjct: 254 S---KPQQSASGNNESSQVESTKEGNPSTTACDSQDEGRPCSMKHKE---SPPSNATAET 307
Query: 282 NPDGVLSKMENLP----EINTAKIKGKNSF 307
P + K++ P E+ A K SF
Sbjct: 308 EP--IPQKLQMPPCSECEVKKAPEKPLTSF 335
>gi|4826657 caldesmon 1 isoform 2 [Homo sapiens]
Length = 538
Score = 40.4 bits (93), Expect = 0.007
Identities = 37/187 (19%), Positives = 79/187 (42%), Gaps = 3/187 (1%)
Query: 9 RHRKDISTEMIRTKIAHRKSLSQKENRHKEYERN-RHFGLKDVNIPTLEGRILVELDETS 67
R +K + +IA++++ +E +E R R L+ G++ +++ +
Sbjct: 11 RRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNA 70
Query: 68 QGLVPEKTNVKPRAMKTILGDQRKQMLQKY--KEEKQLQKLKEQREKAKRGIFKVGRYRP 125
Q VP++ + GD L++ +EE++ ++L+E E+ K +
Sbjct: 71 QNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASL 130
Query: 126 DMPCFLLSNQNAVKAEPKKAIPSSVRITRSKAKDQMEQTKIDNESDVRAIRPGPRQTSEK 185
+P + N A +K S R R + ++ TK ++D R ++ EK
Sbjct: 131 SLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEK 190
Query: 186 KVSDKEK 192
+ ++EK
Sbjct: 191 EEEEEEK 197
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 40.4 bits (93), Expect = 0.007
Identities = 37/187 (19%), Positives = 79/187 (42%), Gaps = 3/187 (1%)
Query: 9 RHRKDISTEMIRTKIAHRKSLSQKENRHKEYERN-RHFGLKDVNIPTLEGRILVELDETS 67
R +K + +IA++++ +E +E R R L+ G++ +++ +
Sbjct: 11 RRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNA 70
Query: 68 QGLVPEKTNVKPRAMKTILGDQRKQMLQKY--KEEKQLQKLKEQREKAKRGIFKVGRYRP 125
Q VP++ + GD L++ +EE++ ++L+E E+ K +
Sbjct: 71 QNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASL 130
Query: 126 DMPCFLLSNQNAVKAEPKKAIPSSVRITRSKAKDQMEQTKIDNESDVRAIRPGPRQTSEK 185
+P + N A +K S R R + ++ TK ++D R ++ EK
Sbjct: 131 SLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEK 190
Query: 186 KVSDKEK 192
+ ++EK
Sbjct: 191 EEEEEEK 197
>gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1
[Homo sapiens]
Length = 1288
Score = 40.4 bits (93), Expect = 0.007
Identities = 51/241 (21%), Positives = 98/241 (40%), Gaps = 31/241 (12%)
Query: 13 DISTEMIRTKIAHRKSLSQKENRHKEYERNRHFGLKDVNIPTLEGRILVELDETSQGLVP 72
D+ +R K+ H S ++K + + ++ + K +IP I+ E + L
Sbjct: 394 DLEDVQVREKLKHATSKAKKLEKQLQKDKEKVEEFK--SIPAKSNNIINETTTRNNALEK 451
Query: 73 EKTNVKPRAMKTILGDQRKQMLQKYKEEKQ-LQKLKEQREKAKRGIFK-VGRYRPDMPC- 129
EK + + K+++ K+E Q LQK KE REK G K V R M
Sbjct: 452 EKEKEEKKL---------KEVMDSLKQETQGLQKEKESREKELMGFSKSVNEARSKMDVA 502
Query: 130 -----FLLSNQNAVKAEPKKAIPSSVRITRSKAKDQMEQTKIDNESDVRAIRPGPRQTSE 184
LS N ++ KA +A +T + ++ +R I G +E
Sbjct: 503 QSELDIYLSRHNTAVSQLTKA---------KEALIAASETLKERKAAIRDIE-GKLPQTE 552
Query: 185 KKVSDKEKKVVQPVMPTS--LRMTRSATQAAKQVPRTVSSTTARKPVTRAANENEPEGKV 242
+++ +KEK++ + + + Q ++ +++ +R V A + + G++
Sbjct: 553 QELKEKEKELQKLTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVLDAIIQEKKSGRI 612
Query: 243 P 243
P
Sbjct: 613 P 613
>gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1
[Homo sapiens]
Length = 1288
Score = 40.4 bits (93), Expect = 0.007
Identities = 51/241 (21%), Positives = 98/241 (40%), Gaps = 31/241 (12%)
Query: 13 DISTEMIRTKIAHRKSLSQKENRHKEYERNRHFGLKDVNIPTLEGRILVELDETSQGLVP 72
D+ +R K+ H S ++K + + ++ + K +IP I+ E + L
Sbjct: 394 DLEDVQVREKLKHATSKAKKLEKQLQKDKEKVEEFK--SIPAKSNNIINETTTRNNALEK 451
Query: 73 EKTNVKPRAMKTILGDQRKQMLQKYKEEKQ-LQKLKEQREKAKRGIFK-VGRYRPDMPC- 129
EK + + K+++ K+E Q LQK KE REK G K V R M
Sbjct: 452 EKEKEEKKL---------KEVMDSLKQETQGLQKEKESREKELMGFSKSVNEARSKMDVA 502
Query: 130 -----FLLSNQNAVKAEPKKAIPSSVRITRSKAKDQMEQTKIDNESDVRAIRPGPRQTSE 184
LS N ++ KA +A +T + ++ +R I G +E
Sbjct: 503 QSELDIYLSRHNTAVSQLTKA---------KEALIAASETLKERKAAIRDIE-GKLPQTE 552
Query: 185 KKVSDKEKKVVQPVMPTS--LRMTRSATQAAKQVPRTVSSTTARKPVTRAANENEPEGKV 242
+++ +KEK++ + + + Q ++ +++ +R V A + + G++
Sbjct: 553 QELKEKEKELQKLTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVLDAIIQEKKSGRI 612
Query: 243 P 243
P
Sbjct: 613 P 613
>gi|15149465 caldesmon 1 isoform 5 [Homo sapiens]
Length = 532
Score = 39.7 bits (91), Expect = 0.012
Identities = 35/175 (20%), Positives = 76/175 (43%), Gaps = 3/175 (1%)
Query: 21 TKIAHRKSLSQKENRHKEYERN-RHFGLKDVNIPTLEGRILVELDETSQGLVPEKTNVKP 79
++IA++++ +E +E R R L+ G++ +++ +Q VP++
Sbjct: 17 SQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTT 76
Query: 80 RAMKTILGDQRKQMLQKY--KEEKQLQKLKEQREKAKRGIFKVGRYRPDMPCFLLSNQNA 137
+ GD L++ +EE++ ++L+E E+ K + +P + N A
Sbjct: 77 TTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTA 136
Query: 138 VKAEPKKAIPSSVRITRSKAKDQMEQTKIDNESDVRAIRPGPRQTSEKKVSDKEK 192
+K S R R + ++ TK ++D R ++ EK+ ++EK
Sbjct: 137 ENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEK 191
>gi|28212280 hypothetical protein LOC283579 [Homo sapiens]
Length = 122
Score = 39.7 bits (91), Expect = 0.012
Identities = 21/38 (55%), Positives = 26/38 (68%)
Query: 802 HLLDSVGSCYVARAGLEVLGSSDPTTSASRVAGTTARS 839
H +GS Y A+AGLE+LGSS+P SAS+ AG T S
Sbjct: 26 HDQPEMGSHYFAQAGLELLGSSNPPASASQSAGITGVS 63
>gi|116174778 centrosome spindle pole associated protein 1 isoform b
[Homo sapiens]
Length = 1221
Score = 39.3 bits (90), Expect = 0.015
Identities = 39/178 (21%), Positives = 74/178 (41%), Gaps = 18/178 (10%)
Query: 25 HRKSLSQKENRH-KEYERNRHFGLKDVNIPTLEGRILVELDETSQGLVPEKTNVKPRAMK 83
HR+++ N + YE R D N+ T L + S G + +T P A
Sbjct: 660 HRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHM--QTQSSPFARG 717
Query: 84 TILGDQRKQMLQK----YKEEKQLQ-KLKEQREKAKRGIFKVGRYRPDMPCFLLSNQNAV 138
+ G+ ++ K YK + Q + K+QRE+A+R ++ + +
Sbjct: 718 NVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRL--------- 768
Query: 139 KAEPKKAIPSSVRITRSKAKDQMEQTKIDNESDVRAIRPGPRQTSEKKVSDKEKKVVQ 196
AE + I + K +++ E+ ++ NE +R ++ KK ++EK +Q
Sbjct: 769 -AEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQ 825
>gi|116174789 centrosome spindle pole associated protein 1 isoform a
[Homo sapiens]
Length = 1256
Score = 39.3 bits (90), Expect = 0.015
Identities = 39/178 (21%), Positives = 74/178 (41%), Gaps = 18/178 (10%)
Query: 25 HRKSLSQKENRH-KEYERNRHFGLKDVNIPTLEGRILVELDETSQGLVPEKTNVKPRAMK 83
HR+++ N + YE R D N+ T L + S G + +T P A
Sbjct: 695 HRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHM--QTQSSPFARG 752
Query: 84 TILGDQRKQMLQK----YKEEKQLQ-KLKEQREKAKRGIFKVGRYRPDMPCFLLSNQNAV 138
+ G+ ++ K YK + Q + K+QRE+A+R ++ + +
Sbjct: 753 NVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRL--------- 803
Query: 139 KAEPKKAIPSSVRITRSKAKDQMEQTKIDNESDVRAIRPGPRQTSEKKVSDKEKKVVQ 196
AE + I + K +++ E+ ++ NE +R ++ KK ++EK +Q
Sbjct: 804 -AEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQ 860
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 38.9 bits (89), Expect = 0.020
Identities = 36/187 (19%), Positives = 65/187 (34%), Gaps = 4/187 (2%)
Query: 133 SNQNAVKAEPKKAIPSSVRITRSKAKDQMEQTKIDNESDVRAIRPGPRQTSEKKVSDKEK 192
S + A PKK +P + ++ K T+ + S+ + Q K
Sbjct: 230 SEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPY 289
Query: 193 KVVQPVMPTSLRMTRSATQAAKQVPRTVSSTTARKPVTRAANENEPEGKVPSKGRPAKNV 252
V P + + K V + ++ + + +E E K P+K +K
Sbjct: 290 SSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKAT 349
Query: 253 ETKPDKGISCKVDSEENTLNSQTNATSGMNPDGVLSKMENLPEINTAKIKGKNSFAPKDF 312
P + + S+ + +S + + P G N P + T K + APK
Sbjct: 350 TKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPK-- 407
Query: 313 MFQPLDG 319
QP+ G
Sbjct: 408 --QPVGG 412
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 38.9 bits (89), Expect = 0.020
Identities = 38/195 (19%), Positives = 86/195 (44%), Gaps = 23/195 (11%)
Query: 7 ASRHRKDISTEMIRTKIAHRKSLSQKENRHKEYERNRHFGLKDVNIPTLEGRILVELDET 66
A + D+ + + K +++ + E++ +E E+ + + E + ++ +E
Sbjct: 621 AEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKK------EVAKKEDKTPIKKEEK 674
Query: 67 SQGLVPEKTNVKPRAMKTILGDQRKQMLQKYKEEKQLQKLKEQREKAKRGIFKVGRYRPD 126
P+K VK K I +++K+ ++ K+E +++K++ +K ++ K P
Sbjct: 675 -----PKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEP- 728
Query: 127 MPCFLLSNQNAVKAEPKKAIPSSVRITRSKAKDQMEQTKIDNESDVR--AIRPG-PRQTS 183
+ +K PK A SS ++ +K ++ E V+ ++ G P++
Sbjct: 729 --------KKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKG 780
Query: 184 EKKVSDKEKKVVQPV 198
+ KV KE K + V
Sbjct: 781 KIKVIKKEGKAAEAV 795
Score = 37.4 bits (85), Expect = 0.059
Identities = 30/122 (24%), Positives = 53/122 (43%), Gaps = 11/122 (9%)
Query: 137 AVKAEPKKAIPSSVRITRSKAKDQMEQTKIDNESDVRAIRPGPRQTSEKKVSDKEKKVVQ 196
+V+ E K+ P ++ + + K++++ V + P +T E K S EK+V
Sbjct: 556 SVRKESKEETPEVTKVNHVE-----KPPKVESKEKVMVKKDKPIKT-ETKPSVTEKEVPS 609
Query: 197 PVMPTSLRMTRSATQAAKQVPRTVSSTTARKPVTRAANENEPEGKVPSKGRPAKNVETKP 256
P+ ++ + QA P+ T +K + +PE K K +P K V K
Sbjct: 610 KEEPSPVKAEVAEKQATDVKPKAAKEKTVKKET-----KVKPEDKKEEKEKPKKEVAKKE 664
Query: 257 DK 258
DK
Sbjct: 665 DK 666
Score = 36.2 bits (82), Expect = 0.13
Identities = 49/243 (20%), Positives = 109/243 (44%), Gaps = 28/243 (11%)
Query: 21 TKIAHRKSLSQKENRHKEYERNRHFGLKDVNIPTLEGRILVELDETS--QGLVPEK--TN 76
TK+ H + + E++ K + + +K P++ + + +E S + V EK T+
Sbjct: 569 TKVNHVEKPPKVESKEKVMVK-KDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATD 627
Query: 77 VKPRAMKTILGDQRKQMLQKYKEEKQLQKLKEQREKAKRGIFKVGRYRPDMPCFLLSNQN 136
VKP+A K ++ ++K + K K KE++EK K+ + K P + +
Sbjct: 628 VKPKAAK-------EKTVKKETKVKPEDK-KEEKEKPKKEVAKKEDKTP-----IKKEEK 674
Query: 137 AVKAEPKKAIPSSVRITRSKAKDQMEQTKIDNESDVRAIRPGPRQTSEKKVSDKEKKVVQ 196
K E KK + ++ K + + + ++ E+ + ++ ++ +K+V +EK+ +
Sbjct: 675 PKKEEVKKEVKKEIK----KEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKK 730
Query: 197 PV--MPTSLRMTRSATQAAKQ----VPRTVSSTTARKPVTRAANENEPEGKVPSKGRPAK 250
+ +P + + + AK+ P+ + K + AA + + +GK+ + K
Sbjct: 731 EIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKEGK 790
Query: 251 NVE 253
E
Sbjct: 791 AAE 793
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 38.9 bits (89), Expect = 0.020
Identities = 61/294 (20%), Positives = 115/294 (39%), Gaps = 49/294 (16%)
Query: 9 RHRKDISTEMIRTKIAHRKSLSQ-KENRHKEYERNRHFGLKDVNIPTLEGRILVELDETS 67
R ++D +R K+ ++ L K+++ K+ E R F + T++ ++ V+
Sbjct: 240 RKKRDEEKAKLR-KLKEKEELETGKKDQSKQKESQRKFEEE-----TVKSKVTVDT---- 289
Query: 68 QGLVP---EKTNVKPRAMKTILGDQRKQMLQKYKEEKQLQKLKEQREKAKRGIFKVGRYR 124
G++P EK A GD++K+ +K K EK E++EK K
Sbjct: 290 -GVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEK------EEKEKEK---------- 332
Query: 125 PDMPCFLLSNQNAVKAEPKKAIPSSVRITRSKAKDQMEQTKIDNESDVRAIR--PGPRQT 182
K P KA +++ +K K++ E+ K + E ++ + R+
Sbjct: 333 --------------KKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKE 378
Query: 183 SEKKVSDKEKKVVQPVMPTSLRMTRSATQAAKQVPRTVSSTTARKPVTRAANENEPEGKV 242
E+ +K ++ Q R+ + K + A + +A P
Sbjct: 379 EERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDS 438
Query: 243 PSKGRPAKNVETKPDKGISCKVDSEENTLNSQTNATSGMNPDGVLSKMENLPEI 296
K RP E K K I +++S+E + + + A + GV K E P +
Sbjct: 439 LPKKRPI--YEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPV 490
Score = 30.0 bits (66), Expect = 9.4
Identities = 50/277 (18%), Positives = 102/277 (36%), Gaps = 41/277 (14%)
Query: 26 RKSLSQKENRHKEYERNRHFGLKDVNIPTLEGRILVELDETSQGLVPEKTNVKPRAMKTI 85
+K +K+ +E E+ + G + ++ + +E + E+ +K
Sbjct: 315 KKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIK------- 367
Query: 86 LGDQRKQMLQKYKEEKQLQKLKEQREKAKRGIFK---------------VGRYRPDMPCF 130
+ +++ K KEE++L++ K +R+K K K R R +
Sbjct: 368 ---RLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLK 424
Query: 131 LLSNQNAVKAEPKKAIPSSVRI----TRSKAKDQMEQTKIDNESDVRAIRPGPRQTSEKK 186
LL Q V+ K ++P I R K Q+E ++ ++ A + E+
Sbjct: 425 LLQAQ-GVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCA----AVEVMEQG 479
Query: 187 VSDKEKKVVQPVMPTSLRMTRSA------TQAAKQVPRTVSSTTARKPVTRAANENEPEG 240
V +KE + PV P T A A+ + V V E E E
Sbjct: 480 VPEKE-ETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEE 538
Query: 241 KVPSKGRPAKNVETKPDKGISCKVDSEENTLNSQTNA 277
+ + ++ E + + + D E+ ++ + ++
Sbjct: 539 EEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDS 575
>gi|57529246 ubiquitin thioesterase 19 [Homo sapiens]
Length = 1318
Score = 38.5 bits (88), Expect = 0.026
Identities = 19/29 (65%), Positives = 21/29 (72%)
Query: 808 GSCYVARAGLEVLGSSDPTTSASRVAGTT 836
GS YVA+AGLE L S DP+ SAS AG T
Sbjct: 44 GSRYVAQAGLEPLASGDPSASASHAAGIT 72
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.354
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,357,509
Number of Sequences: 37866
Number of extensions: 1377195
Number of successful extensions: 5180
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 184
Number of HSP's that attempted gapping in prelim test: 4880
Number of HSP's gapped (non-prelim): 492
length of query: 842
length of database: 18,247,518
effective HSP length: 111
effective length of query: 731
effective length of database: 14,044,392
effective search space: 10266450552
effective search space used: 10266450552
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.