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Search of human proteins with 115392150
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|115392150 hypothetical protein LOC644815 [Homo sapiens]
(823 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|115392150 hypothetical protein LOC644815 [Homo sapiens] 1683 0.0
gi|156564372 hypothetical protein LOC113828 [Homo sapiens] 286 4e-77
gi|153251792 hypothetical protein LOC54854 [Homo sapiens] 212 1e-54
gi|61676089 hypothetical protein LOC222584 [Homo sapiens] 191 2e-48
gi|116235448 hypothetical protein LOC81610 [Homo sapiens] 186 6e-47
gi|157311635 FAM83H [Homo sapiens] 179 1e-44
gi|30425394 hypothetical protein LOC128876 [Homo sapiens] 177 5e-44
gi|46255017 hypothetical protein LOC84985 isoform b [Homo sapiens] 157 3e-38
gi|40254997 hypothetical protein LOC84985 isoform a [Homo sapiens] 157 3e-38
gi|90903231 huntingtin [Homo sapiens] 51 4e-06
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 48 3e-05
gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo sap... 47 6e-05
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 47 7e-05
gi|194239668 SHC (Src homology 2 domain containing) transforming... 46 2e-04
gi|194239662 SHC (Src homology 2 domain containing) transforming... 46 2e-04
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 45 2e-04
gi|194239664 SHC (Src homology 2 domain containing) transforming... 45 3e-04
gi|32261324 SHC (Src homology 2 domain containing) transforming ... 45 3e-04
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 45 4e-04
gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens] 44 5e-04
gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens] 43 0.001
gi|153792074 proline rich 12 [Homo sapiens] 43 0.001
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 42 0.002
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 42 0.002
gi|110349719 titin isoform N2-A [Homo sapiens] 42 0.003
gi|169213235 PREDICTED: hypothetical protein [Homo sapiens] 42 0.003
gi|169212744 PREDICTED: hypothetical protein [Homo sapiens] 42 0.003
gi|182507165 thymus expressed gene 3-like [Homo sapiens] 42 0.003
gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens] 41 0.004
gi|116256464 hypothetical protein LOC343990 [Homo sapiens] 41 0.004
>gi|115392150 hypothetical protein LOC644815 [Homo sapiens]
Length = 823
Score = 1683 bits (4359), Expect = 0.0
Identities = 823/823 (100%), Positives = 823/823 (100%)
Query: 1 MAFSQVQCLDDNHVNWRSSESKPEFFYSEEQRLALEALVARGRDAFYEVLKRENIRDFLS 60
MAFSQVQCLDDNHVNWRSSESKPEFFYSEEQRLALEALVARGRDAFYEVLKRENIRDFLS
Sbjct: 1 MAFSQVQCLDDNHVNWRSSESKPEFFYSEEQRLALEALVARGRDAFYEVLKRENIRDFLS 60
Query: 61 ELELKRILETIEVYDPGSEDPRGTGPSQGPEDNGVGDGEEASGADGVPIEAEPLPSLEYW 120
ELELKRILETIEVYDPGSEDPRGTGPSQGPEDNGVGDGEEASGADGVPIEAEPLPSLEYW
Sbjct: 61 ELELKRILETIEVYDPGSEDPRGTGPSQGPEDNGVGDGEEASGADGVPIEAEPLPSLEYW 120
Query: 121 PQKSDRSIPQLDLGWPDTIAYRGVTRASVYMQPPIDGQAHIKEVVRKMISQAQKVIAVVM 180
PQKSDRSIPQLDLGWPDTIAYRGVTRASVYMQPPIDGQAHIKEVVRKMISQAQKVIAVVM
Sbjct: 121 PQKSDRSIPQLDLGWPDTIAYRGVTRASVYMQPPIDGQAHIKEVVRKMISQAQKVIAVVM 180
Query: 181 DMFTDVDIFKDLLDAGFKRKVAVYIIVDESNVKYFLHMCERACMHLGHLKNLRVRSSGGT 240
DMFTDVDIFKDLLDAGFKRKVAVYIIVDESNVKYFLHMCERACMHLGHLKNLRVRSSGGT
Sbjct: 181 DMFTDVDIFKDLLDAGFKRKVAVYIIVDESNVKYFLHMCERACMHLGHLKNLRVRSSGGT 240
Query: 241 EFFTRSATKFKGALAQKFMFVDGDRAVCGSYSFTWSAARTDRNVISVLSGQVVEMFDRQF 300
EFFTRSATKFKGALAQKFMFVDGDRAVCGSYSFTWSAARTDRNVISVLSGQVVEMFDRQF
Sbjct: 241 EFFTRSATKFKGALAQKFMFVDGDRAVCGSYSFTWSAARTDRNVISVLSGQVVEMFDRQF 300
Query: 301 QELYLMSHSVSLKGIPMEKEPEPEPIVLPSVVPLVPAGTVAKKLVNPKYALVKAKSVDEI 360
QELYLMSHSVSLKGIPMEKEPEPEPIVLPSVVPLVPAGTVAKKLVNPKYALVKAKSVDEI
Sbjct: 301 QELYLMSHSVSLKGIPMEKEPEPEPIVLPSVVPLVPAGTVAKKLVNPKYALVKAKSVDEI 360
Query: 361 AKISSEKQEAKKPLGLKGPALAEHPGELPELLPPIHPGLLHLERANMFEYLPTWVEPDPE 420
AKISSEKQEAKKPLGLKGPALAEHPGELPELLPPIHPGLLHLERANMFEYLPTWVEPDPE
Sbjct: 361 AKISSEKQEAKKPLGLKGPALAEHPGELPELLPPIHPGLLHLERANMFEYLPTWVEPDPE 420
Query: 421 PGSDILGYINIIDPNIWNPQPSQMNRIKIRDTSQASAQHQLWKQSQDSRPRPEPCPPPEP 480
PGSDILGYINIIDPNIWNPQPSQMNRIKIRDTSQASAQHQLWKQSQDSRPRPEPCPPPEP
Sbjct: 421 PGSDILGYINIIDPNIWNPQPSQMNRIKIRDTSQASAQHQLWKQSQDSRPRPEPCPPPEP 480
Query: 481 SAPQDGVPAENGLPQGDPEPLPPVPKPRTVPVADVLARDSSDIGWVLELPKEEAPQNGTD 540
SAPQDGVPAENGLPQGDPEPLPPVPKPRTVPVADVLARDSSDIGWVLELPKEEAPQNGTD
Sbjct: 481 SAPQDGVPAENGLPQGDPEPLPPVPKPRTVPVADVLARDSSDIGWVLELPKEEAPQNGTD 540
Query: 541 HRLPRMAGPGHAPLQRQLSVTQDDPESLGVGLPNGLDGVEEEDDDDYVTLSDQDSHSGSS 600
HRLPRMAGPGHAPLQRQLSVTQDDPESLGVGLPNGLDGVEEEDDDDYVTLSDQDSHSGSS
Sbjct: 541 HRLPRMAGPGHAPLQRQLSVTQDDPESLGVGLPNGLDGVEEEDDDDYVTLSDQDSHSGSS 600
Query: 601 GRGPGPRRPSVASSVSEEYFEVREHSVPLRRRHSEQVANGPTPPPRRQLSAPHITRGTFV 660
GRGPGPRRPSVASSVSEEYFEVREHSVPLRRRHSEQVANGPTPPPRRQLSAPHITRGTFV
Sbjct: 601 GRGPGPRRPSVASSVSEEYFEVREHSVPLRRRHSEQVANGPTPPPRRQLSAPHITRGTFV 660
Query: 661 GPQGGSPWAQSRGREEADALKRMQAQRSTDKEAQGQQFHHHRVPASGTRDKDGFPGPPRY 720
GPQGGSPWAQSRGREEADALKRMQAQRSTDKEAQGQQFHHHRVPASGTRDKDGFPGPPRY
Sbjct: 661 GPQGGSPWAQSRGREEADALKRMQAQRSTDKEAQGQQFHHHRVPASGTRDKDGFPGPPRY 720
Query: 721 RSAADSVQSSTRNAGPAMAGPHHWQAKGGQVPRLLPDPGSPRLAQNARPMTDGRATEEHP 780
RSAADSVQSSTRNAGPAMAGPHHWQAKGGQVPRLLPDPGSPRLAQNARPMTDGRATEEHP
Sbjct: 721 RSAADSVQSSTRNAGPAMAGPHHWQAKGGQVPRLLPDPGSPRLAQNARPMTDGRATEEHP 780
Query: 781 SPFGIPYSKLSQSKHLKARTGGSQWASSDSKRRAQAPRDRKDP 823
SPFGIPYSKLSQSKHLKARTGGSQWASSDSKRRAQAPRDRKDP
Sbjct: 781 SPFGIPYSKLSQSKHLKARTGGSQWASSDSKRRAQAPRDRKDP 823
>gi|156564372 hypothetical protein LOC113828 [Homo sapiens]
Length = 500
Score = 286 bits (733), Expect = 4e-77
Identities = 160/353 (45%), Positives = 216/353 (61%), Gaps = 24/353 (6%)
Query: 1 MAFSQVQCLDDNHVNWRSSESKPEFFYSEEQRLALEALVARGRDAFYEVLKRENIRDFLS 60
MA SQ+ CLD+ HVN + +E++ F+Y E +R ALEAL+ G A+ E LK E +RDFLS
Sbjct: 1 MAESQLNCLDEAHVNEKVTEAQAAFYYCERRRAALEALLGGGEQAYRERLKEEQLRDFLS 60
Query: 61 ELELKRILETIEVYDPGSEDPRGTGPSQGPEDNGVGDGEEASGADGVPIEAEPLPSLEYW 120
E + + Y+ G S+ A P AE SL YW
Sbjct: 61 SPERQALRAAWSPYEDAVPAANARGKSK------------AKAKAPAPAPAESGESLAYW 108
Query: 121 PQKSDRSIPQLDLGWPDTIAYRGVTRASVYMQPPIDGQA-HIKEVVRKMISQAQKVIAVV 179
P +SD +P LDLGW DT YRGV+R +++ PP D +A H+K+VVR+MI QAQKVIAVV
Sbjct: 109 PDRSDTEVPPLDLGWTDTGFYRGVSRVTLFTHPPKDEKAPHLKQVVRQMIQQAQKVIAVV 168
Query: 180 MDMFTDVDIFKDLLDAGFKRKVAVYIIVDESNVKYFLHMCERACMHLGHLKNLRVRSSGG 239
MD+FTD DIF+D++DA KR+V VYII+DE+ VKYFL MC+ + ++N+RVRS G
Sbjct: 169 MDLFTDGDIFQDIVDAACKRRVPVYIILDEAGVKYFLEMCQDLQLTDFRIRNIRVRSVTG 228
Query: 240 TEFFTRSATKFKGALAQKFMFVDGDRAVCGSYSFTWSAARTDRNVISVLSGQVVEMFDRQ 299
F+ + KG L+ +F+ VDGD+ GSY FTWS++ DRN++ +L+GQ VE FD +
Sbjct: 229 VGFYMPMG-RIKGTLSSRFLMVDGDKVATGSYRFTWSSSHVDRNLLLLLTGQNVEPFDTE 287
Query: 300 FQELYLMSHSVSLKGIPMEKEPEPEPIVLPSVVPLVPAGTVAKKLVNPKYALV 352
F+ELY +S V L + L V L + TVA+KL+NPKYALV
Sbjct: 288 FRELYAISEEVDLY----------RQLSLAGRVGLHYSSTVARKLINPKYALV 330
>gi|153251792 hypothetical protein LOC54854 [Homo sapiens]
Length = 478
Score = 212 bits (540), Expect = 1e-54
Identities = 120/328 (36%), Positives = 187/328 (57%), Gaps = 26/328 (7%)
Query: 1 MAFSQVQCLDDNHVNWRSSESKPEFFYSEEQRLALEALVARGRDAFYEVLKRENIRDFLS 60
MA SQ+ L+ R + P F YSE QRLALEAL+++G +AF ++RE + FLS
Sbjct: 1 MAASQLAALEGVDSGPRVPGASPGFLYSEGQRLALEALLSKGAEAFQTCVQREELWPFLS 60
Query: 61 ELELKRILETIEVYDPGSEDPRGTGPSQGPEDNGVGDGEEASGADGVPIEAEPLPSLEYW 120
E++ + E + ++P G A GA ++A SL YW
Sbjct: 61 ADEVQGLAAAAEDWTVAKQEPSGM----------------AEGATTTDVDAG---SLSYW 101
Query: 121 PQKSDRSIPQLDLGWPDTIAYRGVTRASVYMQPPIDGQAHIKEVVRKMISQAQKVIAVVM 180
P +S++ P L LGWP A++G+TRA +Y QPP +GQ +KE+VR I A K++AVVM
Sbjct: 102 PGQSEQPAPVLRLGWPVDSAWKGITRAQLYTQPPGEGQPPLKELVRLEIQAAHKLVAVVM 161
Query: 181 DMFTDVDIFKDLLDAGFKRKVAVYIIVDESNVKYFLHMCERACMHLGHLKNLRVRSSGGT 240
D+FTD D+ DL+DA +R V VY+++D + FL + ++ ++ + +N+ VR G
Sbjct: 162 DVFTDPDLLLDLVDAATRRWVPVYLLLDRQQLPAFLELAQQLGVNPWNTENVDVRVVRGC 221
Query: 241 EFFTRSATKFKGALAQKFMFVDGDRAVCGSYSFTWSAARTDRNVISVLSGQVVEMFDRQF 300
F +R + G + +KF+ +DG+R + GSYSFTWS AR R ++++L+G++V+ F +F
Sbjct: 222 SFQSRWRRQVSGTVREKFVLLDGERVISGSYSFTWSDARLHRGLVTLLTGEIVDAFSLEF 281
Query: 301 QELYLMSHSVSLKGIPMEKEPEPEPIVL 328
+ LY S P+ P +P V+
Sbjct: 282 RTLYAAS-------CPLPPAPPQKPSVI 302
>gi|61676089 hypothetical protein LOC222584 [Homo sapiens]
Length = 1011
Score = 191 bits (485), Expect = 2e-48
Identities = 108/302 (35%), Positives = 170/302 (56%), Gaps = 35/302 (11%)
Query: 7 QCLDDNHVNWRSSESKPEFFYSEEQRLALEALVARGRDAFYEVLKRENIRDFLSELELKR 66
+C DN++ E Y E R+A++ L+ G +A+ E L +E + DFL+E E+
Sbjct: 13 ECKSDNYI---------EPHYKEWYRVAIDILIEHGLEAYQEFLVQERVSDFLAEEEINY 63
Query: 67 ILETIEVYDPGSEDPRGTGPSQGPEDNGVGDGEEASGADGVPIEAEPLPSLEYWPQKSDR 126
IL+ ++ + G +D+ + L S YWP +SD
Sbjct: 64 ILKNVQKV--------AQSTAHGTDDSC----------------DDTLSSGTYWPVESDV 99
Query: 127 SIPQLDLGWPDTI-AYRGVTRASVYMQPPIDGQAHIKEVVRKMISQAQKVIAVVMDMFTD 185
P LDLGWP + G T + PP IKE +RKMI +A+KVIA+VMD+FTD
Sbjct: 100 EAPNLDLGWPYVMPGLLGGTHIDLLFHPPRAHLLTIKETIRKMIKEARKVIALVMDIFTD 159
Query: 186 VDIFKDLLDAGFKRKVAVYIIVDESNVKYFLHMCERACMHLGHLKNLRVRSSGGTEFFTR 245
VDIFK++++A R V+VYI++DESN +FL+M E+ + L+N+RVR+ G ++ ++
Sbjct: 160 VDIFKEIVEAS-TRGVSVYILLDESNFNHFLNMTEKQGCSVQRLRNIRVRTVKGQDYLSK 218
Query: 246 SATKFKGALAQKFMFVDGDRAVCGSYSFTWSAARTDRNVISVLSGQVVEMFDRQFQELYL 305
+ KF G + QKF+ VD + + GSYS+ WS + +++ +++GQ+VE FD +F+ LY
Sbjct: 219 TGAKFHGKMEQKFLLVDCQKVMYGSYSYMWSFEKAHLSMVQIITGQLVESFDEEFRTLYA 278
Query: 306 MS 307
S
Sbjct: 279 RS 280
>gi|116235448 hypothetical protein LOC81610 [Homo sapiens]
Length = 615
Score = 186 bits (473), Expect = 6e-47
Identities = 116/296 (39%), Positives = 166/296 (56%), Gaps = 24/296 (8%)
Query: 23 PEFFYSEEQRLALEALVARGRDAFYEVLKRENIRDFLSELELKRILETIEVYDPGSEDPR 82
P +SE +RLALE LVA G +AF L+RE + FL+ E+ IL E PG E
Sbjct: 54 PTELFSESRRLALEELVAGGPEAFAAFLRRERLARFLNPDEVHAILRAAE--RPGEE--- 108
Query: 83 GTGPSQGPEDNGVGDGEEASGADGVPIEAEPLPSLEYWPQKSDRSIPQLDLGWPDTI--A 140
G + ED+ + +SG Y+P++SD P L+LGWP A
Sbjct: 109 GAAAAAAAEDSFGSSHDCSSGT--------------YFPEQSDLEPPLLELGWPAFYQGA 154
Query: 141 YRGVTRASVYMQPPIDGQAH---IKEVVRKMISQAQKVIAVVMDMFTDVDIFKDLLDAGF 197
YRG TR + QP G+ K+ +R+ + A++VIAVVMD+FTD+DIF+DL +
Sbjct: 155 YRGATRVETHFQPRGAGEGGPYGCKDALRQQLRSAREVIAVVMDVFTDIDIFRDLQEICR 214
Query: 198 KRKVAVYIIVDESNVKYFLHMCERACMHLGHLKNLRVRSSGGTEFFTRSATKFKGALAQK 257
K+ VAVYI++D++ + FL MC +H K + VR+ G ++ RS TK G + +K
Sbjct: 215 KQGVAVYILLDQALLSQFLDMCMDLKVHPEQEKLMTVRTITGNIYYARSGTKIIGKVHEK 274
Query: 258 FMFVDGDRAVCGSYSFTWSAARTDRNVISVLSGQVVEMFDRQFQELYLMSHSVSLK 313
F +DG R GSYSFTW+ + + + + +LSGQVVE FD +F+ LY S +S K
Sbjct: 275 FTLIDGIRVATGSYSFTWTDGKLNSSNLVILSGQVVEHFDLEFRILYAQSKPISPK 330
>gi|157311635 FAM83H [Homo sapiens]
Length = 1179
Score = 179 bits (453), Expect = 1e-44
Identities = 102/281 (36%), Positives = 157/281 (55%), Gaps = 23/281 (8%)
Query: 27 YSEEQRLALEALVARGRDAFYEVLKRENIRDFLSELELKRILETIEVYDPGSEDPRGTGP 86
Y E RLA++AL G +A+ L E DFL EL+ + + + +P
Sbjct: 24 YKEYYRLAVDALAEGGSEAYSRFLATEGAPDFLCPEELEHVSRHLRPPQYVTREP----- 78
Query: 87 SQGPEDNGVGDGEEASGADGVPIEAEPLPSLEYWPQKSDRSIPQLDLGWPDTIAYRGVTR 146
PE + + + G+ G YWP SD+++P+LDLGWP T ++G T
Sbjct: 79 ---PEGSLLD--VDMDGSSGT-----------YWPVNSDQAVPELDLGWPLTFGFQG-TE 121
Query: 147 ASVYMQPPIDGQAHIKEVVRKMISQAQKVIAVVMDMFTDVDIFKDLLDAGFKRKVAVYII 206
+ +QPP IK+ R+MI AQ+V+AVVMDMFTDVD+ ++L+A R+V VYI+
Sbjct: 122 VTTLVQPPPPDSPSIKDEARRMIRSAQQVVAVVMDMFTDVDLLSEVLEAA-ARRVPVYIL 180
Query: 207 VDESNVKYFLHMCERACMHLGHLKNLRVRSSGGTEFFTRSATKFKGALAQKFMFVDGDRA 266
+DE N ++FL M ++ ++L H+ LRVR+ G ++ R+ FKG + +KF+ VD
Sbjct: 181 LDEMNAQHFLDMADKCRVNLHHVDFLRVRTVAGPTYYCRTGKSFKGHVKEKFLLVDCAVV 240
Query: 267 VCGSYSFTWSAARTDRNVISVLSGQVVEMFDRQFQELYLMS 307
+ GSYSF WS + R++ V G++V FD +F+ L+ S
Sbjct: 241 MSGSYSFMWSFEKIHRSLAHVFQGELVSSFDEEFRILFAQS 281
Score = 32.3 bits (72), Expect = 1.8
Identities = 61/276 (22%), Positives = 95/276 (34%), Gaps = 45/276 (16%)
Query: 454 QASAQHQLWKQSQDSRPRPEPCPPPEPSAPQDGVPAENGLP-------QGDP-------- 498
+ S HQ+ +S+ P P +P G G P +G P
Sbjct: 855 EGSGAHQVLHN--ESKGSPTSAYPERKGSPTPGFSTRRGSPTTGFIEQKGSPTSAYPERR 912
Query: 499 -EPLPPVPKPRTVPVADVLARDSS-DIGWVLELPKEEAPQNGTDHRLPRMAGPGHAPLQR 556
P+PPVP+ R+ PV V R S + E PK + G + + G L++
Sbjct: 913 GSPVPPVPERRSSPVPPVPERRGSLTLTISGESPKAGPAEEGPSGPM-EVLRKGSLRLRQ 971
Query: 557 QLSVTQDDPESLGVGLPNGLDGVEEEDDDDYVTLSDQDSHSGSSGRGPGPRRPSV----- 611
LS + G P + + E + + + RGP R S
Sbjct: 972 LLSPKGERRMEDEGGFPVPQENGQPESPRRLSLGQGDSTEAATEERGPRARLSSATANAL 1031
Query: 612 -ASSVSEEYFEVREHSVPLRRRHSEQVANGPTP---------PPRRQLSAPH-------- 653
+S++ ++ + E ++H A P P PP + AP
Sbjct: 1032 YSSNLRDDTKAILEQISAHGQKHRAVPAPSPGPTHNSPELGRPPAAGVLAPDMSDKDKCS 1091
Query: 654 -ITRGTFVGPQGGSPWAQSRGREEAD-ALKRMQAQR 687
I R +G QG EE D L+RM++ R
Sbjct: 1092 AIFRSDSLGTQGRLSRTLPASAEERDRLLRRMESMR 1127
>gi|30425394 hypothetical protein LOC128876 [Homo sapiens]
Length = 747
Score = 177 bits (448), Expect = 5e-44
Identities = 114/330 (34%), Positives = 184/330 (55%), Gaps = 27/330 (8%)
Query: 16 WRSSESKPEFFYSEEQRLALEALVARGRDAFYEVLKRENIRDFLSELELKRILETIEVYD 75
WR S S +SE RLA +AL+ RG A+ V+ E FLS L++ + +
Sbjct: 31 WRES-SPLVLRHSEAARLAADALLERGEAAYLRVISEERELPFLSALDVDYMTSHV---- 85
Query: 76 PGSEDPRGTGPSQGPEDNGVGDGEEASGADGVPIEAEPLPSLEYWPQKSDRSIPQLDLGW 135
RG GPE + G+EASG D + + +E + S Y+P SD P LDLGW
Sbjct: 86 ------RG-----GPELSEA-QGQEASGPDRLSLLSE-VTSGTYFPMASDIDPPDLDLGW 132
Query: 136 PDTIAYRGVTRASVYMQPPIDGQAHIKEVVRKMISQAQKVIAVVMDMFTDVDIFKDLLDA 195
P+ G + + D +IK+++R + SQA V+AVVMD+FTD+++ DL++A
Sbjct: 133 PEVPQATGFSPTQAVVHFQRDKAKNIKDLLRFLFSQAHTVVAVVMDIFTDMELLCDLMEA 192
Query: 196 GFKRKVAVYIIVDESNVKYFLHMCERACMHLGHLKNLRVRSSGGTEFFTRSATKFKGALA 255
+R V VY+++ + ++++FL MC + ++ HL N+RVRS+ G + +++ +F G
Sbjct: 193 SSRRGVPVYLLLAQEHLRHFLEMCYKMDLNGEHLPNMRVRSTCGDTYCSKAGRRFTGQAL 252
Query: 256 QKFMFVDGDRAVCGSYSFTWSAARTDRNVISVLSGQVVEMFDRQFQELYLMSHSVSLKGI 315
+KF+ +D ++ V GSYSFTW ++ +++ L G++VE FDR+F+ LY S V +G
Sbjct: 253 EKFVLIDCEQVVAGSYSFTWLCSQAHTSMVLQLRGRIVEDFDREFRCLYAESQPV--EGF 310
Query: 316 PMEKEP------EPEPIVLPSVVPLVPAGT 339
++P P P+ L + P VP+ T
Sbjct: 311 CGGEDPLSPRALRPPPVAL-AFRPDVPSPT 339
>gi|46255017 hypothetical protein LOC84985 isoform b [Homo sapiens]
Length = 367
Score = 157 bits (398), Expect = 3e-38
Identities = 106/317 (33%), Positives = 165/317 (52%), Gaps = 23/317 (7%)
Query: 9 LDDNHVNWRSSESKPEFFYSEEQRLALEALVARGRDAFYEVLKRENIRDFLSELELKRIL 68
L+D W ++ +F +E RLA +AL+ G +A++ VL +E DFLS +E + I
Sbjct: 14 LEDVKSQW-VRPARADFSDNESARLATDALLDGGSEAYWRVLSQEGEVDFLSSVEAQYI- 71
Query: 69 ETIEVYDPGSEDPRGTGPSQGPEDNGVGDGEEASGADGVPIEAEPLPSLEYWPQKSDRSI 128
+ P P+ G G EA G G +++ L S Y+P S+ S
Sbjct: 72 -----------QAQAREPPCPPDTLG---GAEA-GPKG--LDSSSLQSGTYFPVASEGSE 114
Query: 129 PQLDLGWPDTIA--YRGVTRASVYMQPPIDGQAHIKEVVRKMISQAQKVIAVVMDMFTDV 186
P L W + + A+VY Q +I+++VR+ I++ +V+ ++MD+FTDV
Sbjct: 115 PALLHSWASAEKPYLKEKSSATVYFQTVKHN--NIRDLVRRCITRTSQVLVILMDVFTDV 172
Query: 187 DIFKDLLDAGFKRKVAVYIIVDESNVKYFLHMCERACMHLGHLKNLRVRSSGGTEFFTRS 246
+IF D+L+A KR V V +++D+ VK F MC++ + HLKN+ +RS G + +S
Sbjct: 173 EIFCDILEAANKRGVFVCVLLDQGGVKLFQEMCDKVQISDSHLKNISIRSVEGEIYCAKS 232
Query: 247 ATKFKGALAQKFMFVDGDRAVCGSYSFTWSAARTDRNVISVLSGQVVEMFDRQFQELYLM 306
KF G + +KF+ D + GSYSFTW RN++S +GQ VE+FD +F+ LY
Sbjct: 233 GRKFAGQIREKFIISDWRFVLSGSYSFTWLCGHVHRNILSKFTGQAVELFDEEFRHLYAS 292
Query: 307 SHSVSLKGIPMEKEPEP 323
S V P P P
Sbjct: 293 SKPVMGLKSPRLVAPVP 309
>gi|40254997 hypothetical protein LOC84985 isoform a [Homo sapiens]
Length = 434
Score = 157 bits (398), Expect = 3e-38
Identities = 106/317 (33%), Positives = 165/317 (52%), Gaps = 23/317 (7%)
Query: 9 LDDNHVNWRSSESKPEFFYSEEQRLALEALVARGRDAFYEVLKRENIRDFLSELELKRIL 68
L+D W ++ +F +E RLA +AL+ G +A++ VL +E DFLS +E + I
Sbjct: 14 LEDVKSQW-VRPARADFSDNESARLATDALLDGGSEAYWRVLSQEGEVDFLSSVEAQYI- 71
Query: 69 ETIEVYDPGSEDPRGTGPSQGPEDNGVGDGEEASGADGVPIEAEPLPSLEYWPQKSDRSI 128
+ P P+ G G EA G G +++ L S Y+P S+ S
Sbjct: 72 -----------QAQAREPPCPPDTLG---GAEA-GPKG--LDSSSLQSGTYFPVASEGSE 114
Query: 129 PQLDLGWPDTIA--YRGVTRASVYMQPPIDGQAHIKEVVRKMISQAQKVIAVVMDMFTDV 186
P L W + + A+VY Q +I+++VR+ I++ +V+ ++MD+FTDV
Sbjct: 115 PALLHSWASAEKPYLKEKSSATVYFQTVKHN--NIRDLVRRCITRTSQVLVILMDVFTDV 172
Query: 187 DIFKDLLDAGFKRKVAVYIIVDESNVKYFLHMCERACMHLGHLKNLRVRSSGGTEFFTRS 246
+IF D+L+A KR V V +++D+ VK F MC++ + HLKN+ +RS G + +S
Sbjct: 173 EIFCDILEAANKRGVFVCVLLDQGGVKLFQEMCDKVQISDSHLKNISIRSVEGEIYCAKS 232
Query: 247 ATKFKGALAQKFMFVDGDRAVCGSYSFTWSAARTDRNVISVLSGQVVEMFDRQFQELYLM 306
KF G + +KF+ D + GSYSFTW RN++S +GQ VE+FD +F+ LY
Sbjct: 233 GRKFAGQIREKFIISDWRFVLSGSYSFTWLCGHVHRNILSKFTGQAVELFDEEFRHLYAS 292
Query: 307 SHSVSLKGIPMEKEPEP 323
S V P P P
Sbjct: 293 SKPVMGLKSPRLVAPVP 309
>gi|90903231 huntingtin [Homo sapiens]
Length = 3144
Score = 51.2 bits (121), Expect = 4e-06
Identities = 26/70 (37%), Positives = 32/70 (45%)
Query: 454 QASAQHQLWKQSQDSRPRPEPCPPPEPSAPQDGVPAENGLPQGDPEPLPPVPKPRTVPVA 513
Q Q Q +Q Q +P P P PPP P PQ A+ LPQ P P PP P P
Sbjct: 25 QQQQQQQQQQQQQQQQPPPPPPPPPPPQLPQPPPQAQPLLPQPQPPPPPPPPPPGPAVAE 84
Query: 514 DVLARDSSDI 523
+ L R ++
Sbjct: 85 EPLHRPKKEL 94
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 48.1 bits (113), Expect = 3e-05
Identities = 131/549 (23%), Positives = 183/549 (33%), Gaps = 101/549 (18%)
Query: 313 KGIPMEKEPEPEPIVLPSVVPLVPA-GTVAKKLVNPKYALVKAK-----SVDEIAKISSE 366
K +P P P P P PA A+ P A S + S E
Sbjct: 526 KELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFE 585
Query: 367 KQEAKKPLGLK-GPALAEHPGELPELLPPIHPGLLHLERANMFEYLPTWVEPDPEPGSDI 425
+ L K GP E P E+P PP P + +E + P +P S
Sbjct: 586 ASPVEPQLPSKEGP---EPPEEVP---PPTTPPVPKVEPKG------DGIGPTRQPPSQG 633
Query: 426 LGYINIIDPNIWNPQPSQMNRIKIRDTSQASAQHQLWKQSQDSRPRPEPCPPPEPSAPQD 485
LGY P P + R + + QHQ W+Q Q P P PP P
Sbjct: 634 LGY-----PKYQKSLPPRFQRQQQEQLLKQQQQHQ-WQQHQQGSAPPTPVPPSPPQPVTL 687
Query: 486 GVPAENGLPQGDPEPLPPVPKPRTVPVADVLARDSSDIGWVLELPKEEAPQNGTDHRLPR 545
G P P+ L P R P+ + + D W++ P + PR
Sbjct: 688 GAVPAPQAPPPPPKALYPGALGRPPPMPPM----NFDPRWMMIPPYVD----------PR 733
Query: 546 MAGPGHAPLQRQLSVTQDDPESLGVGLPNGLDGVEEEDDDDYVTLSDQ-DSHSGSSGRGP 604
+ G PL D GV P+GL V E D + S+ D H+ + R
Sbjct: 734 LL-QGRPPL---------DFYPPGVH-PSGL--VPRERSDSGGSSSEPFDRHAPAMLRER 780
Query: 605 G-----PRRPSVASSVSEEYFEVREHSVPLRRRHSE-----QVANGPTPPPRRQLSA--- 651
G P+ V + E R + PLR+ E + P PPP L++
Sbjct: 781 GTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPG 840
Query: 652 --------PHITRGTFVGPQGGSPWAQSRGREEADALKRMQAQRSTDKEAQGQQF--HHH 701
P I+R P G P G +E ++ ++ KE Q
Sbjct: 841 FPENGAPGPPISRFPLEEP-GPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAG 899
Query: 702 RVPASGTRDKDGFPGPPRYRSAADSVQSSTRNAGPAMAGPHHWQAKGGQVPRLLP--DPG 759
R PA G P PPR S ++ W + G R +P +PG
Sbjct: 900 RKPARGVGSGGQGPPPPRRESRTET----------------RWGPRPGSSRRGIPPEEPG 943
Query: 760 SP--RLAQNARPMTDGRATEEHPSPF--GIPYSKLSQSKHLKARTG--GSQWASSDSKRR 813
+P R +P + E P P G K + LK G G + +
Sbjct: 944 APPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNL 1003
Query: 814 AQAPRDRKD 822
+ APR R+D
Sbjct: 1004 SPAPRLRRD 1012
Score = 37.4 bits (85), Expect = 0.057
Identities = 70/312 (22%), Positives = 110/312 (35%), Gaps = 52/312 (16%)
Query: 542 RLPRMAGP-GHAPLQRQL------SVTQDDP----ESLGVGLPNGLDGVEEEDD-DDYVT 589
R PR+AGP G P R + S+ ++D + L +G G EE D + +
Sbjct: 281 RFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLK 340
Query: 590 LSDQDSHSGSSGRGPGPRRPSVASSVSEEYFEV--REHSVPLRRRHSEQVANGPT----- 642
SD++ S G R S ++S E E ++ + P + + A T
Sbjct: 341 FSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPE 400
Query: 643 -----PPPRRQLSAPHITRGTFVGPQGGSP------------------WAQSRGREEAD- 678
P P+ L PH GP G P W Q R + ++
Sbjct: 401 TEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEI 460
Query: 679 ALKRMQAQRSTDKEAQGQQFHHHRVPASGTRDKDGFPGPPRYRSAADSVQSSTRNAGPAM 738
+L +A+R ++E + Q A + D G P R A+ + PA
Sbjct: 461 SLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAP 520
Query: 739 AGPHHWQAKGGQVPRLLPDPGSPRLAQNARPMTDGRATEEHPSPFGIPYSKLSQSKHLKA 798
VP+ LP P +P A P T+ + P P ++ + L +
Sbjct: 521 PPA---------VPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVS 571
Query: 799 RTGGSQWASSDS 810
G + SS S
Sbjct: 572 GGGSTSSTSSGS 583
Score = 32.7 bits (73), Expect = 1.4
Identities = 28/109 (25%), Positives = 40/109 (36%), Gaps = 5/109 (4%)
Query: 468 SRPRPEPCPPPEPSAPQDGVPAENGLPQGDPEPLPPVPKPRTVPVADVLARDS--SDIGW 525
S P P P P E AP PA P+ +PE P ++ P V A + S G
Sbjct: 516 STPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGS 575
Query: 526 VLELPKEEAPQNGTDHRLPRMAG---PGHAPLQRQLSVTQDDPESLGVG 571
+ + +LP G P P V + +P+ G+G
Sbjct: 576 TSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIG 624
>gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo sapiens]
Length = 1747
Score = 47.4 bits (111), Expect = 6e-05
Identities = 91/406 (22%), Positives = 138/406 (33%), Gaps = 59/406 (14%)
Query: 333 PLVPAGTVAKKLVNPKYALVKAKSVDEIAKISSEKQEAKKPLGLKGPALAEHPGELPE-L 391
PL P+ +A L + AL + S + PL + A G L
Sbjct: 1117 PLDPSSPLALALAARERALASQAPSRSPTPVHSPDADRPGPLFVDVQARDPERGSLASPA 1176
Query: 392 LPPIHPGLLHLERANMFEYLPTWVEPDPEPGSDILGYINIIDPNIWNPQPSQMNRIKIRD 451
P P + + E +P PE ++ ++++D ++ P I +
Sbjct: 1177 FSPRSPAWIPVPARREAEKVPREERKSPEDKKSMI--LSVLDTSLQRPA----GLIVVHA 1230
Query: 452 TSQASAQHQLWKQSQDSRPRPEPCPPPEPSA------------PQDGVPAENGLPQGDPE 499
TS +L ++ PE P P SA P G PA+ G QG E
Sbjct: 1231 TSNGQEPSRLGGAEEERPGTPELAPAPMQSAAVAEPLPSPRAQPPGGTPADAGPGQGSSE 1290
Query: 500 PLPPVPKPRTVPVADVLARDS---SDIGWVLELPKEEAPQNGTDHRLPRMAGPGHAPLQR 556
P + +P A + + D ++ + +P E NG P +AGPG +P
Sbjct: 1291 EEPELVFAVNLPPAQLSSSDEETREELARIGLVPPPEEFANGVLLATP-LAGPGPSPTTV 1349
Query: 557 QLSVTQDDPESLGVGLPNGL--DGVEEEDDDDYVTLSDQDSHSGSSGRGPGPRRPSVASS 614
S P S P GVEE D T S D H ++ S S+
Sbjct: 1350 P-SPASGKPSSEPPPAPESAADSGVEEAD-----TRSSSDPHLETTST---ISTVSSMST 1400
Query: 615 VSEEYFEVREHSVPLRRRHSEQVANGPTPPPRRQLSAPHITRGTFVGPQGGSPWAQSRGR 674
+S E E+ + H+ + P PP + S P G P
Sbjct: 1401 LSSESGELTDTHTSFADGHTFLLEKPPVPPKPKLKS-----------PLGKGP------- 1442
Query: 675 EEADALKRMQAQRSTDKEAQGQQFHHHRVPASGTRDKDGFPGPPRY 720
+ ++S+D E QQ H ++G G P PRY
Sbjct: 1443 ---VTFRDPLLKQSSDSELMAQQ---HHAASAGLASAAG-PARPRY 1481
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 47.0 bits (110), Expect = 7e-05
Identities = 79/363 (21%), Positives = 121/363 (33%), Gaps = 65/363 (17%)
Query: 478 PEPSAPQDGVPAENGLPQGDPEPLPPVPK----------PRTVPVADVLARDSSDIGWVL 527
P PS+ P+++ LP +P PVP +T PVA S G V
Sbjct: 2425 PSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVA---GSQSLSSGAVA 2481
Query: 528 ELPKEEAPQNGTDHRLPRMAGPGHAPLQRQLSVTQDDPESLGVGLPNGLDGVEEEDDDDY 587
NG + + PG S + P S G P+ L ++ +
Sbjct: 2482 TTTSSAGDHNG----MLSVPAPGVPH-----SDVGEPPASTGAQQPSALAALQPAKERRS 2532
Query: 588 VTLSDQDSHSGSSGRGPGPRRPSVASSVSEEYFEVREHSVPLRRRHSEQVANGPTPPPRR 647
+ S S S SS S SS S+ S+P++ + + PTP P+
Sbjct: 2533 SSSSSSSSSSSSSSSSSSSSSSSSGSSSSDS----EGSSLPVQPEVALKRVPSPTPAPKE 2588
Query: 648 QLSAPHITRGTFVGPQGGSPWAQSRGREEADALKRMQAQRSTDKEAQGQQFHHHRVPASG 707
+ + R E A ++ ++ S+ + +S
Sbjct: 2589 AV-------------------REGRPPEPTPAKRKRRSSSSSSSSSSSSS-------SSS 2622
Query: 708 TRDKDGFPGPPRYRSAADSVQSSTRNAGPAMAGPHHWQAKGGQVPRLLPDPGSPRLAQNA 767
+ S++ S SS+ + PA GP QA P PG R
Sbjct: 2623 SSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGP---QALPKPASPKKPPPGERRSRSPR 2679
Query: 768 RP---MTDGRA------TEEHPSPFGIPYSKLSQSKHLKARTGGSQWASSDS-KRRAQAP 817
+P + D R+ PSP P + S S +R G + S S KRR + P
Sbjct: 2680 KPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETP 2739
Query: 818 RDR 820
R
Sbjct: 2740 SPR 2742
Score = 44.7 bits (104), Expect = 4e-04
Identities = 90/402 (22%), Positives = 137/402 (34%), Gaps = 49/402 (12%)
Query: 434 PNIWNPQPSQMNRIKIRDTSQASAQHQLWKQSQDSRPRPEP---CPPPEPSAPQDGVPAE 490
P QPS K +D + SA +RP P P PEP AP +
Sbjct: 324 PETATKQPSSPYEDKDKDKKEKSA----------TRPSPSPERSSTGPEPPAPTPLLAER 373
Query: 491 NGLPQGDPEPLPPVP---KPRTVPVADVLARDSSDIGWVLELPK--EEAPQNGTDHRLPR 545
+G G P+PL P +P P RD S PK E+ PQ+ + P
Sbjct: 374 HG---GSPQPLATTPLSQEPVNPPSEASPTRDRSP-------PKSPEKLPQSSSSESSP- 422
Query: 546 MAGPGHAPLQRQLSVTQDDPE-SLGVGLPNGLDGVEEEDDDDYVTLSDQDSHSGSSGRGP 604
P + R S + + P+ + G + + + SHS + R
Sbjct: 423 -PSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRM 481
Query: 605 GPRRPSVASSVSEEYFEVREHSVPLRRRHSEQVANGPTPPPRRQLSAPHITRGTFVGPQG 664
G R + P +R HS +P RR SA R +G
Sbjct: 482 GRSRSPATAKRGRS-----RSRTPTKRGHS----RSRSPQWRRSRSAQRWGRSRSPQRRG 532
Query: 665 GS------PWAQSRGREEADALKRMQAQRSTDKEAQGQQFHHHRVPASGTRDKDGFPGPP 718
S W++SR + + + RS + + R PA R + P
Sbjct: 533 RSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARR 592
Query: 719 RYRSAADSVQSSTRNAGPAMAGPHHWQAKGGQVPRLLPDPGSPRLAQNARPMTDGRATEE 778
R RS + + S R+ PA G + + R P R + GR+
Sbjct: 593 RSRSRTPTRRRS-RSRTPARRGRSRSRTPARRRSR-TRSPVRRRSRSRSPARRSGRSRSR 650
Query: 779 HPSPFGIPYSKLSQSKHLKARTGGSQWASSDSKRRAQAPRDR 820
P+ G S+ + ++ ++R+ S S+ R A R R
Sbjct: 651 TPARRGRSRSR-TPARRGRSRSRTPARRSGRSRSRTPARRGR 691
Score = 44.7 bits (104), Expect = 4e-04
Identities = 83/396 (20%), Positives = 131/396 (33%), Gaps = 49/396 (12%)
Query: 438 NPQPSQMNRIKIRDTSQASAQHQLWKQSQDSRPRPEPCPPPEPSAPQDGVPAENGLPQGD 497
+P R +R S++ + ++ +S+ S R PE P
Sbjct: 1562 SPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSS 1621
Query: 498 PEPLPPVPKPRTVPVADVLARDSSDIGWVLELPKEEAPQNGTDHRLPRMAGPGHAPLQRQ 557
PEP P PR +P S G P E + + P H P R
Sbjct: 1622 PEPK--APAPRALPRRSRSGSSSKGRG-----PSPEGSSS-------TESSPEHPPKSRT 1667
Query: 558 L---SVTQDDPESLGVGLPNGLDGVEEEDDDDYVTLSDQDSHSGSSGRGPGPRRPSVASS 614
S + +P++ P + LS + + SS P S
Sbjct: 1668 ARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRS 1727
Query: 615 VSEEYFEVREHSVPLRRRHS---------EQVANGPTPPPR-----RQLSAPHITRGTFV 660
S E E S RRR S + P+P PR R S TR T
Sbjct: 1728 PSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRR 1787
Query: 661 GPQGGSPWAQSRGREEADALKRMQAQRSTDKEAQGQQFHHHRVPASGTRDKDGFPGPPRY 720
+ GS + SR R+ + + R+ +R +G +H R PA + R
Sbjct: 1788 RDRSGSSQSTSRRRQRSRSRSRVTRRR------RGGSGYHSRSPARQESSRTS----SRR 1837
Query: 721 RSAADSVQSSTRNAGPAMAGPHHWQAKGGQVPRLLPDPGSPRLAQNARPMTDGRATEEHP 780
R ++R + P W+ R P + R +++ P+ R +
Sbjct: 1838 RRGRSRTPPTSRKRSRSRTSPAPWKRS-----RSRASPATHRRSRSRTPLISRRRSRSRT 1892
Query: 781 SPFGIPYSKLSQSKHLKARTGGSQWASSDSKRRAQA 816
SP + S+S+ R AS S+RR+++
Sbjct: 1893 SPVS---RRRSRSRTSVTRRRSRSRASPVSRRRSRS 1925
Score = 32.3 bits (72), Expect = 1.8
Identities = 39/183 (21%), Positives = 64/183 (34%), Gaps = 32/183 (17%)
Query: 578 GVEEEDDDDYVT-----LSDQDSHSGSSGRGPGPR------------------RPSVASS 614
G EE+ + V L ++D + G PG R R A
Sbjct: 81 GYEEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFG 140
Query: 615 VSEEYFEVREHSVPLRRRHSEQVANGPTPPPRRQLSAPHITRGTFVGPQGGSPWAQSRGR 674
+S+ Y + R R ++Q A P PP L + + Q + RGR
Sbjct: 141 ISDSYVDGSSFDPQRRAREAKQPA--PEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGR 198
Query: 675 EEADALKRMQAQRSTDKEAQGQQFHHHRVPASGTRDKDGFPGPPRYRSAADSVQSSTRNA 734
+ R + ++S+ K+ HR + + K P P R + D + +R+
Sbjct: 199 RSESSSPRRERKKSSKKKK-------HRSESESKKRKHRSPTPKSKRKSKDKKRKRSRST 251
Query: 735 GPA 737
PA
Sbjct: 252 TPA 254
>gi|194239668 SHC (Src homology 2 domain containing) transforming
protein 1 isoform 4 [Homo sapiens]
Length = 473
Score = 45.8 bits (107), Expect = 2e-04
Identities = 56/227 (24%), Positives = 79/227 (34%), Gaps = 61/227 (26%)
Query: 477 PPEPSAPQDGVPAENGLPQGDPEPLPPVPKPRTVPVADVLARDSSDIGWVLELPKEEAPQ 536
PP+ P D + +G + E PP D + + P +E P
Sbjct: 209 PPKLVTPHDRMAGFDGSAWDEEEEEPP------------------DHQYYNDFPGKEPPL 250
Query: 537 NGT-DHRLPRMAGPGHAPLQRQLSVTQDDPESLGVGLPNG------------------LD 577
G D RL A PG A R + P LG LP G
Sbjct: 251 GGVVDMRLREGAAPGAA---RPTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCP 307
Query: 578 GVEEEDDDDYVTLSDQDSHSGSSGRGPGPRRPSVASSVSEEYFEVREHSVPLRRRHSEQV 637
G E DD YV + + D + G G GP P++ S + F+++ LR
Sbjct: 308 GRELFDDPSYVNVQNLDKARQAVG-GAGPPNPAINGSAPRDLFDMKPFEDALR------- 359
Query: 638 ANGPTPPPRRQLSAPHITRGTFVGPQGGSPWAQSR-GREEADALKRM 683
PPP + +S R G PW + R EA+AL ++
Sbjct: 360 ----VPPPPQSVSMAEQLR--------GEPWFHGKLSRREAEALLQL 394
>gi|194239662 SHC (Src homology 2 domain containing) transforming
protein 1 isoform 1 [Homo sapiens]
Length = 583
Score = 45.8 bits (107), Expect = 2e-04
Identities = 56/227 (24%), Positives = 79/227 (34%), Gaps = 61/227 (26%)
Query: 477 PPEPSAPQDGVPAENGLPQGDPEPLPPVPKPRTVPVADVLARDSSDIGWVLELPKEEAPQ 536
PP+ P D + +G + E PP D + + P +E P
Sbjct: 319 PPKLVTPHDRMAGFDGSAWDEEEEEPP------------------DHQYYNDFPGKEPPL 360
Query: 537 NGT-DHRLPRMAGPGHAPLQRQLSVTQDDPESLGVGLPNG------------------LD 577
G D RL A PG A R + P LG LP G
Sbjct: 361 GGVVDMRLREGAAPGAA---RPTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCP 417
Query: 578 GVEEEDDDDYVTLSDQDSHSGSSGRGPGPRRPSVASSVSEEYFEVREHSVPLRRRHSEQV 637
G E DD YV + + D + G G GP P++ S + F+++ LR
Sbjct: 418 GRELFDDPSYVNVQNLDKARQAVG-GAGPPNPAINGSAPRDLFDMKPFEDALR------- 469
Query: 638 ANGPTPPPRRQLSAPHITRGTFVGPQGGSPWAQSR-GREEADALKRM 683
PPP + +S R G PW + R EA+AL ++
Sbjct: 470 ----VPPPPQSVSMAEQLR--------GEPWFHGKLSRREAEALLQL 504
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 45.4 bits (106), Expect = 2e-04
Identities = 28/79 (35%), Positives = 34/79 (43%), Gaps = 11/79 (13%)
Query: 470 PRPEPCPPPEPSAPQDGVPAENGLPQGDPEPL--PPVPKPRTVPVADVLARDSSDIGWVL 527
P EP PPP P AP P L + EPL PPVP P + + AR
Sbjct: 4910 PPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPK------- 4962
Query: 528 ELPKEEAPQNGTDHRLPRM 546
P+ P+ G D R PR+
Sbjct: 4963 --PRARPPEEGEDSRPPRL 4979
Score = 42.4 bits (98), Expect = 0.002
Identities = 86/351 (24%), Positives = 117/351 (33%), Gaps = 65/351 (18%)
Query: 312 LKGIPMEKEP-EPEPIVLPSVVPLVPAGTVAKK--------LVNPKYALVKAKSVDEIAK 362
L G P EP EP LP +PL P+G + L P ++ A + ++
Sbjct: 894 LLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSP 953
Query: 363 ISSEKQEAKKPLGLKGPALAEHPGELPELLPPIHPGLLHLERANMF--EYLPTWVEPDPE 420
+ E + P G KG + E P P L PI P AN E +P + P P
Sbjct: 954 LG----ELEYPFGAKGDSDPESPLAAPILETPISPP----PEANCTDPEPVPPMILP-PS 1004
Query: 421 PGSDILGYINIIDPNIWNPQPSQMNRIKIRDTSQASAQHQLWKQSQDSRPRPEPCPPPEP 480
PGS + P + P P Q + + QH L Q+ P C PP
Sbjct: 1005 PGSP----VGPASPILMEPLPPQCSPL---------LQHSLVPQNSP----PSQCSPP-- 1045
Query: 481 SAPQDGVPAENGLPQGDPEPLPPVPKPRTVPVADVLARDSSDIGWVLELPKEEAPQNGTD 540
LP P PL P+ K V V+D + V E P+ A +
Sbjct: 1046 -----------ALPLSVPSPLSPIGK--VVGVSDEAELHEMETEKVSE-PECPALEPSAT 1091
Query: 541 HRLPRMAG------PGHAPLQRQLSVTQDDPESLGVGLPNGLDGVEEEDDDDYVTLSDQD 594
LP G P AP S +D L +G+D + + S
Sbjct: 1092 SPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPL-----DGIDAPGSQPEPGQTPGSLAS 1146
Query: 595 SHSGSSG-RGPGPRRPSVASSVSEEYFEVREHSVPLRRRHSEQVANGPTPP 644
GS P P V E + P + + PTPP
Sbjct: 1147 ELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPP 1197
Score = 33.5 bits (75), Expect = 0.82
Identities = 55/227 (24%), Positives = 81/227 (35%), Gaps = 58/227 (25%)
Query: 470 PRPEPCPPPEPS------APQDGVPAENGLP---QGDPEPLPPVPKP---RTVPVADVLA 517
P P P P EP +P +P E LP G P+P P +P R P A LA
Sbjct: 4307 PTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLA 4366
Query: 518 RDSSDIGWVLELPKEEAPQNGTDHRLPRMAG--PGH--------APLQRQLSVTQ---DD 564
D + L + P N + + P + PGH P QLS+ Q ++
Sbjct: 4367 ----DTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREE 4422
Query: 565 PESLGV--------GLPNGLDGVEEEDDDDYVTLSDQDSHSG---------------SSG 601
P +LG G P G G +++ L+ S +G S+G
Sbjct: 4423 PCALGAQSVKREANGEPIGAPGT-----SNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTG 4477
Query: 602 RGPGPRRPSVASSVSEEYFEVREHSVPLRRRHSEQVANGP-TPPPRR 647
RG R + + + + + + A P TP P+R
Sbjct: 4478 RGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKPKR 4524
Score = 33.1 bits (74), Expect = 1.1
Identities = 30/105 (28%), Positives = 44/105 (41%), Gaps = 9/105 (8%)
Query: 470 PRPEPCP---PPE--PSAPQDGVPAENGLPQGDPEPLPPVPKPRTVPVADVLARDSSDIG 524
P PE P PPE P++P + P+ P PP P + P D L +
Sbjct: 664 PPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEES 723
Query: 525 WVLELPKEE--APQNGTDHRLPRMAGPGHAPLQRQ--LSVTQDDP 565
+L LP+E P++ H PR P +P + LS ++P
Sbjct: 724 PLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEP 768
Score = 31.6 bits (70), Expect = 3.1
Identities = 76/349 (21%), Positives = 118/349 (33%), Gaps = 64/349 (18%)
Query: 470 PRPEPCPPP---EPSAPQDGVPAE-----NGLPQGDPEPLPPVPKPRTVPVADVLARDSS 521
P P PP S P G P E G P+ P P KPR + ++ +S
Sbjct: 2202 PTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESP 2261
Query: 522 DIGWVLELPKEEAPQNGTDHRLPRMAGPGHAPLQRQLSVTQDD---------PESLG-VG 571
+G G P ++ P ++ L V +++ P +LG V
Sbjct: 2262 GVG-------------GGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVD 2308
Query: 572 LPNG---LDGVEEEDDDDY---VTLSDQDSHSGSSGRGPGPRRPSVASSVSE------EY 619
P+ L G+E + D + +T S G G P+ P A +++ +
Sbjct: 2309 SPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDI 2368
Query: 620 FEVREHSVPLRRRHSEQVANGPTPPPRRQLSA--PHITRGTFVGPQGGSPWAQSRGREEA 677
F ++ P + + P PPP A P SP +QS +
Sbjct: 2369 FRPGSYTDPYAQ---PPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPL 2425
Query: 678 DALK-RMQAQRSTDKEAQGQQFHHHRVPASGTRDKDGF--------PGPPRYRSAADSVQ 728
+A + + Q + P S + +D F P PP A S+
Sbjct: 2426 TPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLA 2485
Query: 729 SSTRNAG--PAM-----AGPHHWQAKGGQVPRLLPDPGSPRLAQNARPM 770
++ AG PA AG H + GQ P + PG+ PM
Sbjct: 2486 HTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPM 2534
>gi|194239664 SHC (Src homology 2 domain containing) transforming
protein 1 isoform 3 [Homo sapiens]
Length = 584
Score = 45.1 bits (105), Expect = 3e-04
Identities = 56/228 (24%), Positives = 79/228 (34%), Gaps = 62/228 (27%)
Query: 477 PPEPSAPQDGVPAENGLPQGDPEPLPPVPKPRTVPVADVLARDSSDIGWVLELPKEEAPQ 536
PP+ P D + +G + E PP D + + P +E P
Sbjct: 319 PPKLVTPHDRMAGFDGSAWDEEEEEPP------------------DHQYYNDFPGKEPPL 360
Query: 537 NGT-DHRLPRMAGPGHAPLQRQLSVTQDDPESLGVGLPNGLD------------------ 577
G D RL A PG A R + P LG LP G
Sbjct: 361 GGVVDMRLREGAAPGAA---RPTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCP 417
Query: 578 -GVEEEDDDDYVTLSDQDSHSGSSGRGPGPRRPSVASSVSEEYFEVREHSVPLRRRHSEQ 636
G E DD YV + + D + G G GP P++ S + F+++ LR
Sbjct: 418 AGRELFDDPSYVNVQNLDKARQAVG-GAGPPNPAINGSAPRDLFDMKPFEDALR------ 470
Query: 637 VANGPTPPPRRQLSAPHITRGTFVGPQGGSPWAQSR-GREEADALKRM 683
PPP + +S R G PW + R EA+AL ++
Sbjct: 471 -----VPPPPQSVSMAEQLR--------GEPWFHGKLSRREAEALLQL 505
>gi|32261324 SHC (Src homology 2 domain containing) transforming
protein 1 isoform 2 [Homo sapiens]
Length = 474
Score = 45.1 bits (105), Expect = 3e-04
Identities = 56/228 (24%), Positives = 79/228 (34%), Gaps = 62/228 (27%)
Query: 477 PPEPSAPQDGVPAENGLPQGDPEPLPPVPKPRTVPVADVLARDSSDIGWVLELPKEEAPQ 536
PP+ P D + +G + E PP D + + P +E P
Sbjct: 209 PPKLVTPHDRMAGFDGSAWDEEEEEPP------------------DHQYYNDFPGKEPPL 250
Query: 537 NGT-DHRLPRMAGPGHAPLQRQLSVTQDDPESLGVGLPNGLD------------------ 577
G D RL A PG A R + P LG LP G
Sbjct: 251 GGVVDMRLREGAAPGAA---RPTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCP 307
Query: 578 -GVEEEDDDDYVTLSDQDSHSGSSGRGPGPRRPSVASSVSEEYFEVREHSVPLRRRHSEQ 636
G E DD YV + + D + G G GP P++ S + F+++ LR
Sbjct: 308 AGRELFDDPSYVNVQNLDKARQAVG-GAGPPNPAINGSAPRDLFDMKPFEDALR------ 360
Query: 637 VANGPTPPPRRQLSAPHITRGTFVGPQGGSPWAQSR-GREEADALKRM 683
PPP + +S R G PW + R EA+AL ++
Sbjct: 361 -----VPPPPQSVSMAEQLR--------GEPWFHGKLSRREAEALLQL 395
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 44.7 bits (104), Expect = 4e-04
Identities = 72/323 (22%), Positives = 110/323 (34%), Gaps = 34/323 (10%)
Query: 464 QSQDSRPRPEPCPPPE-PS-------APQDGVPAENGLPQGDPEPLPPVPKPRTVPVADV 515
+S S P P P P P PS AP G E + + P P PP T PV +
Sbjct: 600 RSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEP 659
Query: 516 LARDSSDIGWVLELPKEEAPQNGTDHRLPRMAG---PGHAPLQRQLSVTQDDPESLGVGL 572
E P P+ T +G G + R LSV+ S
Sbjct: 660 TKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSS 719
Query: 573 PNGLDGVEEEDDDDYVTLSDQDSHSGSSGRGPGPRRPSVASSVSEEYFEVREHSVPLRRR 632
+ V+ E D Y L+ S +S R P P + S++ V+E +R
Sbjct: 720 SSSAHSVDSE--DMYADLA--SPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEK--RKRD 773
Query: 633 HSEQVANGPTPP--------PRRQLSAP--HITRGTFVGPQGGSPWAQSRGREEADALKR 682
S Q PP P AP +GTFV + ++ ++ ++
Sbjct: 774 SSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGS--RK 831
Query: 683 MQAQRSTDKEAQGQQFHHHRVPASGTRDKD-----GFPGPPRYRSAADSVQSSTRNAGPA 737
D+++ + P G+RD+ G P P R R ++ +
Sbjct: 832 RYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQ 891
Query: 738 MAGPHHWQAKGGQVPRLLPDPGS 760
++ +K VP DPG+
Sbjct: 892 LSPQSKSSSKVTSVPGKASDPGA 914
>gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens]
Length = 1349
Score = 44.3 bits (103), Expect = 5e-04
Identities = 86/388 (22%), Positives = 120/388 (30%), Gaps = 85/388 (21%)
Query: 465 SQDSRPRPEPCPPPEPSAPQDGVPAENGLPQGDPEPLPPVPKPR-------TVPVADVLA 517
S P P PE +P V + LP P P +P+ T+P+
Sbjct: 973 SSPGEVEPPPFYVPEVGSPLSSVMSSPPLPTEGPFGHPTIPEENGENASNSTLPLTQTPT 1032
Query: 518 RDSSDIGWVLELPKEEAPQNGTDHRLPRMAGPGHAPLQRQLSVTQDDPESLG--VGLPNG 575
S W + E P G + P M P P D PESL GLP G
Sbjct: 1033 GGRSPEPW----GRPEFPFGGLE--TPAMMFPHQLP-------PCDVPESLQPKAGLPRG 1079
Query: 576 LDGVEEEDDDDYVTLSDQDSHSGSSGRGPG---------------PRRPSVASSVSEEYF 620
L + Y + ++ G +G+ PG P +P V+
Sbjct: 1080 LPPTSLQVPAAYPGILSLEAPKGWAGKSPGRGPVPAPPAAKWQDRPMQPLVSQGQLRHTS 1139
Query: 621 EVREHSVPLRRRHSEQVANG-----------------PTPPPRRQLSAPHITRGTFVGPQ 663
+ V +E A+G P P PR+ A + P
Sbjct: 1140 QGMGIPVLPYPEPAEPGAHGGPSTFGLDTRWYEPQPRPRPSPRQARRAEPSLHQVVLQPS 1199
Query: 664 GGSPWAQS-------------RGREEADALKRMQAQRSTDKEAQGQQFHHHRVPASGTRD 710
SP QS R R L++ + T + F P++G+
Sbjct: 1200 RLSPLTQSPLSSRTGSPELAARARPRPGLLQQAEMSEITLQPPAAVSFSRKSTPSTGSPS 1259
Query: 711 KDGFPGPPRYRSAADSVQSST----RNAGPAMAGPHHWQAKGGQVPR--------LLPDP 758
+ G P YR A +T GPA AGP GQ P L P+
Sbjct: 1260 QSSRSGSPSYRPAMGFTTLATGYPSPPPGPAPAGPGDSLDVFGQTPSPRRTGEELLRPET 1319
Query: 759 GSPRLAQNARPMTDGRATEEHPSPFGIP 786
P L T G+ + P+P P
Sbjct: 1320 PPPTLP------TSGKLQRDRPAPATSP 1341
Score = 32.3 bits (72), Expect = 1.8
Identities = 46/199 (23%), Positives = 72/199 (36%), Gaps = 18/199 (9%)
Query: 598 GSSGR---GPGPRRPSVASSVSEEYFEVREHSVPLRRRHSEQVANGPTPPP-----RRQL 649
G GR P PS+ S E + E + R S++ P P + QL
Sbjct: 853 GPDGRFVMDPAEMEPSLKSRRIEGFPFAEETDMYPEFRQSDEENEDPLVPTSVAALKSQL 912
Query: 650 SAPHITRGTFVGPQGGSPWAQSRGREEADALK-RMQAQRSTDKEAQGQQFHHHRVPASGT 708
+ ++ +++ P SP Q RG E L+ R+QA A + FHH + +
Sbjct: 913 TPLSSSQESYLPPPAYSPRFQPRGLEGPGGLEGRLQATGQARPPAP-RPFHHGQYYGYLS 971
Query: 709 RDKDG-FPGPPRYRSAADSVQSSTRNAGPAMAGPHHWQAKGGQVPRLLPDPGSPRLAQNA 767
G PP Y S SS ++ P +G +P+ + +
Sbjct: 972 SSSPGEVEPPPFYVPEVGSPLSSVMSSPPL-------PTEGPFGHPTIPEENGENASNST 1024
Query: 768 RPMTDGRATEEHPSPFGIP 786
P+T P P+G P
Sbjct: 1025 LPLTQTPTGGRSPEPWGRP 1043
>gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]
Length = 1006
Score = 43.1 bits (100), Expect = 0.001
Identities = 75/320 (23%), Positives = 108/320 (33%), Gaps = 50/320 (15%)
Query: 417 PDPEPGSDILGYINIIDPNIWNPQPSQMNRIKIRDTSQASAQHQLWKQSQDSRPRPEPCP 476
P P PGSD QPS R + R+T S+D P P
Sbjct: 283 PPPIPGSD---------------QPSSHGRPRFRETGD----------SEDCPPFRAGTP 317
Query: 477 PPEPSAPQDGVPAENGLPQGDPEPLPPVPKPRTVPV---ADVLARDSSDIGWVLELPKEE 533
P +P+AP P P P P+P+P +P D A G V P+
Sbjct: 318 PQQPTAPSSEWPGPQRSPGTGPRWTAPLPRPAPLPAKRPGDSPASKRPRPGGV--SPEAR 375
Query: 534 APQNGTDHRLPRMAGPGHAPLQRQLSVTQDDPESLGVGLPNGLDGVEEEDDDDYVTLSDQ 593
P G + A P Q + P++LG G G G E + + V+
Sbjct: 376 DPPKGENPLCSSEAAGETGPTQVR------GPDALGGGRLQG-KGREGKAPGEGVSPRPA 428
Query: 594 DSHSGSSGRGPGPRRPSVASSVSEEYFEVREHSVPL--RRRHSEQVANGPTPPPRRQLSA 651
G+ P R P + E +F R VP+ + +G L A
Sbjct: 429 PPR---LGKPPRSRPPQGLAQPPETFFFERSRLVPVSAELERAGHGFSGDAEARSGDLGA 485
Query: 652 PHITRGTFVGPQGGSPWAQSRGREEADALKRMQAQRSTDKEAQGQQFHHHRV-PASGTRD 710
+R + P +P AQ + A + A R + A G Q H P+ T
Sbjct: 486 RPASRSSL--PSAPAPPAQ-----QPQAARHGAAGRDQGRRAAGAQLHDPTTQPSPPTGA 538
Query: 711 KDGFPGPPRYRSAADSVQSS 730
+ P Y D ++S+
Sbjct: 539 QQVEEDPADYEEFEDILESA 558
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 43.1 bits (100), Expect = 0.001
Identities = 44/176 (25%), Positives = 62/176 (35%), Gaps = 38/176 (21%)
Query: 470 PRPEPCPPPEPSAPQDGVPAENGLPQGDPEPLPPVPKPRTVPVADVLARDSSDIGWVLEL 529
P P+P PPP P PQ +P+ L P PP P P P A +
Sbjct: 1465 PTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPA---------------M 1509
Query: 530 PKEEAPQNGTDHRLPRMAGPGHAPLQRQLSVTQDDPESLGVGLPNGLDGVEEEDDDDYVT 589
P P P A P AP + + + +DPE LP+ + +
Sbjct: 1510 PSPPPPP-------PPAAAPLAAPPEEPAAPSPEDPE-----LPDTRPLHLAKKQETAAV 1557
Query: 590 LSDQDSHSGSSGRGPGPRRPSVASSVSEEYFEVREHSVPLRRRHSEQVANGPTPPP 645
+ D +G SG G G R + F +R +P + + G PPP
Sbjct: 1558 CGETDEEAGESG-GEGIFR-------ERDEFVIRAEDIPSLKL---ALQTGREPPP 1602
Score = 38.5 bits (88), Expect = 0.026
Identities = 37/147 (25%), Positives = 53/147 (36%), Gaps = 13/147 (8%)
Query: 470 PRPEPCPPPEPSAPQDGVPAENGLPQGDP--------EPLPPVPKPRTVPVADVLARDSS 521
P P P P P+P P P + LP P P PP+P P +
Sbjct: 1459 PTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPP 1518
Query: 522 DIGWVLELPKEEAPQNGTDHRLPRMAGPGHAPLQRQLSVTQDDPESLGVGLPNGLDGVEE 581
+ P+E A + D LP A Q +V + E G +G +G+
Sbjct: 1519 AAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEAG---ESGGEGIFR 1575
Query: 582 EDDDDYVTLSDQDS--HSGSSGRGPGP 606
E D+ + D S + +GR P P
Sbjct: 1576 ERDEFVIRAEDIPSLKLALQTGREPPP 1602
Score = 30.4 bits (67), Expect = 7.0
Identities = 66/281 (23%), Positives = 89/281 (31%), Gaps = 35/281 (12%)
Query: 356 SVDEIAKISSEKQEAKKPLGLKGPALAEHPGELPELLPP--IHPGLLHLERANMFEYLPT 413
S+DE A + E + KGP E GE PE L +H G E + P
Sbjct: 709 SLDEGATAALELGLGRLKEKKKGP---ERGGETPEGLATSVVHYGAGAKELGAFLQKSPP 765
Query: 414 WVEP-----DPEPGSDILGYINIIDPNIWNPQPSQMNRIKIRDTSQASAQ------HQLW 462
P P P +L P + P P Q+ + S H L
Sbjct: 766 PPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLE 825
Query: 463 KQSQDSRPRPEPCPPPEPSAPQDGVPAENGLPQGDPEPLPPVPKPRTVPVADVLARDSSD 522
++D P+P P PP P P + E L EP P P+ R D
Sbjct: 826 PATRDGAPQPPP--PPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQEL 883
Query: 523 IGWVLEL-----------PKEEAPQNGTDHRLPRMAG---PGHAPLQRQL---SVTQDDP 565
+G + L P E +R P G P PL S+ QD+
Sbjct: 884 LGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEE 943
Query: 566 ESLGVGLPNGLDGVEEEDDDDYVTLSDQDSHSGSSGRGPGP 606
S + G +D D+ +G PGP
Sbjct: 944 RSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGP 984
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 42.0 bits (97), Expect = 0.002
Identities = 78/312 (25%), Positives = 100/312 (32%), Gaps = 61/312 (19%)
Query: 476 PPPEPSAPQDGVPAENGLPQGDPEPLPPVPKPRTVPVADVLARDS-SDIGWVLELPKEEA 534
PPP P PQ P PQG P P P P P D +R S S G P+
Sbjct: 132 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP---PQGDNKSRSSRSPPG----KPQGPP 184
Query: 535 PQNGTDHRLPRMAGPGHAPLQRQLSVTQDDPESLGVGLPNGLDGVEEEDDDDYVTLSDQD 594
PQ G + GP P + Q Q + G P G + D
Sbjct: 185 PQGGNQPQ-----GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD---------- 229
Query: 595 SHSGSSGRGPGPRRPSVASSVSEEYFEVREHSVPLRRRHSEQVANGPTPPPRRQLSAPHI 654
+ S R P P +P P + + Q GP PPP + P
Sbjct: 230 -NKSQSARSP-PGKP---------------QGPPPQGGNQPQ---GPPPPPGKPQGPPPQ 269
Query: 655 TRGTFVGPQGGSPWAQSRGREEADALKRMQAQRSTDKEAQGQQFHHHRVPASGTRDKDGF 714
PQG P + +G K ++ RS + QG P G G
Sbjct: 270 GGNK---PQGPPPPGKPQGPPPQGGSK-SRSSRSPPGKPQGP-------PPQGGNQPQG- 317
Query: 715 PGPPRYRSAADSVQSSTRNAGPAMAG-PHHWQAKGGQVPR-LLPDPGSPRLAQNARPMTD 772
P PP + Q + GP G P +GG R PG P+ P +
Sbjct: 318 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQ----GPPQQE 373
Query: 773 GRATEEHPSPFG 784
G + P P G
Sbjct: 374 GNNPQGPPPPAG 385
Score = 40.8 bits (94), Expect = 0.005
Identities = 79/314 (25%), Positives = 99/314 (31%), Gaps = 62/314 (19%)
Query: 476 PPPEPSAPQDGVPAENGLPQGDPEPLPPVPKPRTVPVADVLARDSSDIGWVLELPKEEAP 535
PPP P PQ P PQG P P P P P D S G P+ P
Sbjct: 71 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP---PQGDKSRSPRSPPG----KPQGPPP 123
Query: 536 QNGTDHRLPRMAGPGHAPLQRQLSVTQDDPESLGVGLPNGLDGVEEEDDDDYVTLSDQDS 595
Q G + GP P + Q Q + G P G + D+
Sbjct: 124 QGGNQPQ-----GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG----------DN 168
Query: 596 HSGSSGRGPG-PRRPSVASSVSEEYFEVREHSVPLRRRHSEQVANGPTPPPRRQLSAPHI 654
S SS PG P+ P P + + Q GP PPP + P
Sbjct: 169 KSRSSRSPPGKPQGP------------------PPQGGNQPQ---GPPPPPGKPQGPPPQ 207
Query: 655 TRGTFVGPQGGSPWAQSRGREEADALKRMQAQRSTDKEAQGQQFHHHRVPASGTRDKDGF 714
PQG P + +G + Q+ RS + QG P G G
Sbjct: 208 GGNK---PQGPPPPGKPQG-PPPQGDNKSQSARSPPGKPQGP-------PPQGGNQPQG- 255
Query: 715 PGPPRYRSAADSVQSSTRNAGPAMAG-PHHWQAKGGQVPR-LLPDPGSPRLAQNARPMTD 772
P PP + Q + GP G P +GG R PG P+ P
Sbjct: 256 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQ----GPPPQG 311
Query: 773 GRATEEHPSPFGIP 786
G + P P G P
Sbjct: 312 GNQPQGPPPPPGKP 325
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 42.0 bits (97), Expect = 0.002
Identities = 46/235 (19%), Positives = 89/235 (37%), Gaps = 26/235 (11%)
Query: 604 PGPRRPSVASSVSEEYFEVREHSVPLRRRHSEQVANGPTPPPRRQLSAPHITRGTFVGP- 662
P PRR + + R +S P++RR+S P+PPP+R+ ++P P
Sbjct: 575 PPPRRRTPSPPPRRRSPSPRRYSPPIQRRYS------PSPPPKRRTASPPPPPKRRASPS 628
Query: 663 --------------QGGSPWAQSRGREEADALKRMQAQRSTDKEAQGQQFHHHRVPASGT 708
Q SP + R + ++ + + +EA+ Q + P+
Sbjct: 629 PPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRP 688
Query: 709 RDKDGFPGPPRYRSAADSVQSSTRNAGPAMAGPHHWQAKGGQVPRLLPDPGSPRLAQNAR 768
R PP R A S S R P+ + + P+ + SP Q+ R
Sbjct: 689 RAPQTSSSPPPVRRGASS--SPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS-PQSVR 745
Query: 769 PMTDGRATEEHPSPFGIPYSKLSQSKHLKARTGGSQWASSDSKRRAQAPRDRKDP 823
++ R+ P P + +++++ + W+ + ++A++P P
Sbjct: 746 RVSSSRSVSGSPEP--AAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSP 798
Score = 38.5 bits (88), Expect = 0.026
Identities = 85/411 (20%), Positives = 131/411 (31%), Gaps = 61/411 (14%)
Query: 439 PQPSQMNRIKIRDTSQASAQHQLWKQSQDSRPRPEPCPPPEPSAPQDGVPAENGLPQGDP 498
P+PS +K+++ S A + D P+P P PEP P P +N + +
Sbjct: 224 PEPS----VKVKEPSVQEAT-----STSDILKVPKPEPIPEPKEPS---PEKNSKKEKEK 271
Query: 499 EPLPPVPKPRTVPVADVLARDSSDIGWVLELPKEEAPQNGTDHRLPRMAGPGHAPLQRQL 558
E P + R+ + +R S P+ + R P P R+
Sbjct: 272 EKTRPRSRSRSKSRSRTRSRSPSHTR-----PRRRHRSRSRSYSPRRRPSPRRRPSPRRR 326
Query: 559 SVTQDDPESLGVGLPNGLDGVEEEDDDDYVTLSDQDSHSGSSGRGPGPRRPSVASSVSEE 618
+ + P V S S S R P + P SS +
Sbjct: 327 TPPRRMPPP--PRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRK 384
Query: 619 YFEVREHSVPLRRRHSEQVANGPTPPPRRQLS----------------APHITRGTFVGP 662
+ + P RRRH + + TPPP+ + S +P T G
Sbjct: 385 TRRLSPSASPPRRRH--RPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKH 442
Query: 663 QG------GSPWAQSR----GREEADALKRMQAQRSTDKEAQGQQFHHHRVPASGTRDKD 712
+G SP + R E D +M A S + Q ++ + SG+
Sbjct: 443 KGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSS 502
Query: 713 GFPGPPRYRSAADSVQSSTRNAGPAMAGPHHWQAKGGQVPRLLPDPGSPRLAQNARPMTD 772
P R V R++ A P PR SPR + P
Sbjct: 503 EDERPKRSHVKNGEVGRRRRHSPSRSASPS---------PRKRQKETSPRGRRRRSPSPP 553
Query: 773 GRATEEHPSPFGIPYSKLSQSKHLKARTGGSQWASSDSKRRAQAPRDRKDP 823
PSP P + + + + RT S +RR+ +PR P
Sbjct: 554 PTRRRRSPSPAPPPRRRRTPTPPPRRRT-----PSPPPRRRSPSPRRYSPP 599
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 41.6 bits (96), Expect = 0.003
Identities = 64/259 (24%), Positives = 93/259 (35%), Gaps = 66/259 (25%)
Query: 284 VISVLSGQVVEMFDRQFQELYLMSHSVSLKGIPMEKEP-----EPEPIVLPSVVPLVPAG 338
VI V + VE+F++ + +S K IP +K P EP P+ VP VP
Sbjct: 10421 VIEVFEAEEVEVFEKP--KAPPKGPEISEKIIPPKKPPTKVVPRKEP---PAKVPEVPKK 10475
Query: 339 TVAKKLVN-PKYALVKAKSVDEIAKISSEKQEAKKPLGLKGPALAEHPGELPELLPPIHP 397
V ++ V P+ V V E+ E K P+ P + PE PP P
Sbjct: 10476 IVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVP---------PAKKPEAPPPKVP 10526
Query: 398 GLLHLERANMFEYLPTWVEPDPEPGSDILGYINIIDPNIWNPQPSQMNRIKIRDTSQASA 457
E +P P P P + ++ K+ + +A+
Sbjct: 10527 EAPK-------EVVPEKKVPVPPP------------------KKPEVPPTKVPEVPKAAV 10561
Query: 458 QHQLWKQSQDSRPRPEPCPPPEPSAPQDGVPAENGLPQGDPEPLPPVPKPRTVPVADVLA 517
+ K + P+PE PP P AP++ VP + P P KP PV
Sbjct: 10562 PEK--KVPEAIPPKPESPPPEVPEAPKEVVPEKK-------VPAAPPKKPEVTPVK---- 10608
Query: 518 RDSSDIGWVLELPKEEAPQ 536
V E PKE P+
Sbjct: 10609 --------VPEAPKEVVPE 10619
Score = 36.6 bits (83), Expect = 0.097
Identities = 42/202 (20%), Positives = 72/202 (35%), Gaps = 41/202 (20%)
Query: 345 VNPKYALVKAKSVDEIAKISSEKQEAKKPLGLKGPALAEHPGELPELLPPIHPGLLHLER 404
V ++ + K V E+ + + K KGP ++E +++PP P
Sbjct: 10409 VEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISE------KIIPPKKP------- 10455
Query: 405 ANMFEYLPTWVEPDPEPGSDILGYIN--IIDPNIWNPQPSQMNRIKIRDTSQASAQHQLW 462
PT V P EP + + +++ + P+ ++ K+ +
Sbjct: 10456 -------PTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEK 10508
Query: 463 KQSQDSRPRPEPCPPPEPSAPQDGVPAENGLPQGDPEPLPPVPKPRTVPVADVLARDSSD 522
K +PE PP P AP++ VP + P+PP KP P
Sbjct: 10509 KVPVPPAKKPEAPPPKVPEAPKEVVPEKK-------VPVPPPKKPEVPPTK--------- 10552
Query: 523 IGWVLELPKEEAPQNGTDHRLP 544
V E+PK P+ +P
Sbjct: 10553 ---VPEVPKAAVPEKKVPEAIP 10571
Score = 35.8 bits (81), Expect = 0.17
Identities = 54/212 (25%), Positives = 81/212 (38%), Gaps = 51/212 (24%)
Query: 315 IPMEKEPEPEPIVLPSVVPLVPAGTVAKKLVNPKYALVKAKSVDEIAKISSEKQEAKKPL 374
+P E+E PE VLP V P VP ++ K V E + +K+EA
Sbjct: 10161 VPEEEEFVPEEEVLPEVKPKVPVPAPVPEI---------KKKVTEKKVVIPKKEEAP--- 10208
Query: 375 GLKGPALAEHPGELPELLPPIHPGLLHLERANMFEYLPTWV--EPDPEPGSDILGYINII 432
P ++PE+ + + L + E LP V EP+ EP I
Sbjct: 10209 ----------PAKVPEVPKKVEEKRIILPKEE--EVLPVEVTEEPEEEP---------IS 10247
Query: 433 DPNIWNPQPSQMNRIKIRDTSQASAQH--QLWKQSQDSRPRPEP----CPPPEPS--APQ 484
+ I PS I + + + ++ K++ P P P PP + S P+
Sbjct: 10248 EEEIPEEPPS------IEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPE 10301
Query: 485 DGVPAENGLPQGDPEPLPPVPKPRTVPVADVL 516
+ VP + P +P VPK VP VL
Sbjct: 10302 EKVPVPVQKKEAPPAKVPEVPK--KVPEKKVL 10331
Score = 35.8 bits (81), Expect = 0.17
Identities = 61/255 (23%), Positives = 93/255 (36%), Gaps = 35/255 (13%)
Query: 315 IPMEKEPE---PEPIVLPSVVPLVPAGTVAKKLVN---PKYALVKAKSVDEIAKISSEKQ 368
+P +K PE P+P P VP P V +K V PK V V E K ++
Sbjct: 10561 VPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEK 10620
Query: 369 EAKKPLGLKG----------PALAEHPGELPELLPPIH----PGLLHLERANMFEYLPTW 414
+ P K P +A ++PE +PP P + E P
Sbjct: 10621 KVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAE 10680
Query: 415 VEPDPEPGSDILGYINIIDPNIWNPQPS------QMNRIKIRDTSQASAQHQLWKQSQDS 468
V +PEP + + P P+ ++ +K+ + + + K
Sbjct: 10681 VVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEK--KVPLVV 10738
Query: 469 RPRPEPCPPPEPSAPQDGVPAENGL----PQGDPEPLPPVPKPRTV---PVADVLARDSS 521
+PE P P P++ VP + P+ P +P VPK + P V R S
Sbjct: 10739 PKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAES 10798
Query: 522 DIGWVLELPKEEAPQ 536
V E P+E AP+
Sbjct: 10799 PPPEVYEEPEEIAPE 10813
Score = 35.4 bits (80), Expect = 0.22
Identities = 51/222 (22%), Positives = 87/222 (39%), Gaps = 19/222 (8%)
Query: 316 PMEKEPEPEPIV-LPSVVPLVPAGTVAKKLVNPKYALVKAKSVDEIAKISSEKQEAKKPL 374
P KEPEPE ++ P + P P A + K + + K++ + K EK + + +
Sbjct: 10861 PPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPK--KKVPEKPQVPEKV 10918
Query: 375 GLKGPALAEHPGELPELLPPIHPGLLH-LERANMFEYLPTWVEPDPEPGSDILGYINIID 433
L + ++ +LLP P + ++ P EP EP +
Sbjct: 10919 ELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKK----LEKVKK 10974
Query: 434 PNIWNPQPSQMNRIKIRDTSQASAQHQLWKQSQDSRPRPE-PCPPPEPSAPQDGVPAENG 492
P + P P + ++ + + ++ + ++ +P P P PEP +
Sbjct: 10975 PAVPEPPPPKPVE-EVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIK 11033
Query: 493 LPQGDPEPLPPVPKPRTVPVADVLARDSSDIGWVLELPKEEA 534
P +PEP P+ P TVPV A + PKEEA
Sbjct: 11034 PPPVEPEP-TPIAAPVTVPVVGKKAE--------AKAPKEEA 11066
Score = 35.0 bits (79), Expect = 0.28
Identities = 64/262 (24%), Positives = 98/262 (37%), Gaps = 39/262 (14%)
Query: 315 IPMEKEPEP---EPIVLPSVVPLVPAGTVAKKLVN---PKYALVKAKSVDEIAKISSEKQ 368
+P +K P P +P P VP P V +K V PK V V E+ K + ++
Sbjct: 10505 VPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEK 10564
Query: 369 EAKKPLGLKG----PALAEHPGEL-PELLPPIHPGLLHLERANMFEYLPTWVEPDPEPGS 423
+ + + K P + E P E+ PE P P E P V PE
Sbjct: 10565 KVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAP-------PKKPEVTPVKV---PEAPK 10614
Query: 424 DILGYINIIDPNIWNPQPSQMNRIKIRDTSQASAQHQLWKQSQDSRPRPEPCPPPEPSAP 483
+++ + P P+ ++ K+ + + + + K + P+PE PPPE
Sbjct: 10615 EVVPEKKVPVPP---PKKPEVPPTKVPEVPKVAVPEK--KVPEAIPPKPES-PPPEVFEE 10668
Query: 484 QDGVPAENGLPQGDPEPLPPVPKPRTVP----------VADVLARDSSDIGWVLELPKEE 533
+ V E + EP P P TVP A V + V E+PKE
Sbjct: 10669 PEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEV 10728
Query: 534 APQNGTDHRLPRM--AGPGHAP 553
P+ +P+ A P P
Sbjct: 10729 VPEKKVPLVVPKKPEAPPAKVP 10750
Score = 34.7 bits (78), Expect = 0.37
Identities = 34/132 (25%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 375 GLKG-PALAEHPGELPELLPPIHPGLLHLERANMFEYLPTWVEPDPEPGSDILGY-INII 432
GLK P +A HP ++P+ PP P ++ + ++ TW +P GS I GY +
Sbjct: 20161 GLKSEPIVARHPFDVPDAPPP--PNIVDVRHDSV---SLTWTDPKKTGGSPITGYHLEFK 20215
Query: 433 DPN--IW---NPQPSQMNRIKIRDTSQASAQHQLWKQSQDSRPRPEPCPPPEPSAPQDGV 487
+ N +W N P +M K+ ++ +++ + + +P P EP D +
Sbjct: 20216 ERNSLLWKRANKTPIRMRDFKVTGLTE-GLEYEFRVMAINLAGVGKPSLPSEPVVALDPI 20274
Query: 488 PAENGLPQGDPE 499
P G PE
Sbjct: 20275 D-----PPGKPE 20281
Score = 34.7 bits (78), Expect = 0.37
Identities = 34/99 (34%), Positives = 47/99 (47%), Gaps = 13/99 (13%)
Query: 337 AGTVAKKLVNP--KYALVKA----KSVDEIAKISSEKQ-EAKKPLGLKGPALAEHPGELP 389
+GT A +LVN K +K K ++ ++SSE + KPL P +AEHP P
Sbjct: 28783 SGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLE-SAPIIAEHPFVPP 28841
Query: 390 ELLPPIHPGLLHLERANMFEYLPTWVEPDPEPGSDILGY 428
P P + H+ AN W EP + GS I+GY
Sbjct: 28842 SA--PTRPEVYHVS-ANAMSI--RWEEPYHDGGSKIIGY 28875
Score = 33.1 bits (74), Expect = 1.1
Identities = 35/138 (25%), Positives = 54/138 (39%), Gaps = 30/138 (21%)
Query: 362 KISSEKQEAKKPLGLKGPALAEHPGELPELLPPIHPGLLHLERANMFEYLPTWVEPDPEP 421
++ +E + K +AE+P P PP P ++H ++ M L TW P +
Sbjct: 25560 RVCAENRYGKSSYSESSAVVAEYPFSPPG--PPGTPKVVHATKSTM---LVTWQVPVNDG 25614
Query: 422 GSDILGY---INIIDPNIWNPQPSQMNRIKIRDTSQ----------------ASAQHQLW 462
GS ++GY +W S+ N+I I DT A +
Sbjct: 25615 GSRVIGYHLEYKERSSILW----SKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIG 25670
Query: 463 KQSQDSRPRP--EPCPPP 478
K S+ P P +PC PP
Sbjct: 25671 KCSKSCEPVPARDPCDPP 25688
Score = 32.3 bits (72), Expect = 1.8
Identities = 42/186 (22%), Positives = 73/186 (39%), Gaps = 28/186 (15%)
Query: 310 VSLKGIPMEKEPEPE-PIVLP-------SVVPLVPAGTVA-KKLVNPKYALVKAKSVDEI 360
V + +P E PE + P+V+P + VP VP V KK+ PK V V E+
Sbjct: 10719 VKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEV 10778
Query: 361 AKISSEKQEAKKPLGLKGPALAEHPGELPELLPPIHPGLLHLERANMFEYLPTWVEPDPE 420
K +++ P+ + + E PE + P E+ +P E +PE
Sbjct: 10779 PKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKP-----VPVAEEEEPE 10833
Query: 421 PGSDILGYINIIDPNIWNPQPSQM---NRIKIRDTSQASAQHQLWKQSQDSRPRPEPCPP 477
+ P +P ++ ++ + +A + + +P+ +P PP
Sbjct: 10834 -----------VPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPP 10882
Query: 478 PEPSAP 483
P P AP
Sbjct: 10883 PPPPAP 10888
Score = 30.4 bits (67), Expect = 7.0
Identities = 61/295 (20%), Positives = 103/295 (34%), Gaps = 58/295 (19%)
Query: 275 WSAARTDRNVISVLSGQVVEMFDRQFQELYLMSHSVSLKGIPMEKEPEPEPIVLPSVVPL 334
W A +R VI V +E+Y SH + EK+ P P V+
Sbjct: 9140 WEEAYQEREVIQVQ------------KEVYEESHERKVPAKVPEKKAPPPPKVI------ 9181
Query: 335 VPAGTVAKKLVNPKYALVKAKSVDEIAKISSEKQEAKKPLGLKGPALAEHPGELPELLPP 394
KK V K + +E +++ + +KK + K + +P
Sbjct: 9182 -------KKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPA 9234
Query: 395 IHPGLLHLERANMFEYLPTWVEPD---PEPGSDILGYINI-------IDPNIWNPQ---- 440
+H + + MF T E PE +I+ I ++P P+
Sbjct: 9235 VHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEK 9294
Query: 441 --PSQMNRIKIRDTSQASAQH--QLWKQSQDSRPRPEPCPPPEPSA-------PQDGVPA 489
P ++ + I + A ++ K+ +P P P EP+A P+ VP
Sbjct: 9295 PAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPE 9354
Query: 490 EN-GLPQGDPEPLPPVPKPRT-------VPVADVLARDSSDIGWVLELPKEEAPQ 536
E +P + PP P + V R+ S V E+PK++ P+
Sbjct: 9355 EKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPE 9409
Score = 30.4 bits (67), Expect = 7.0
Identities = 15/42 (35%), Positives = 26/42 (61%), Gaps = 3/42 (7%)
Query: 413 TWVEPDPEPGSDILGY-INIIDPNIWNPQPSQMNRIKIRDTS 453
TW EPD + GS I GY + +DP+ + + N++ ++DT+
Sbjct: 13902 TWCEPDDDGGSPITGYWVERLDPD--TDKWVRCNKMPVKDTT 13941
Score = 30.4 bits (67), Expect = 7.0
Identities = 43/182 (23%), Positives = 65/182 (35%), Gaps = 35/182 (19%)
Query: 384 HPGELPELL-------PPIHPGLLHLERANMFEYLPTWVEPDPEPGSDILGY---INIID 433
HP E E+L PP P LH+ A W P+ GS I+GY + +
Sbjct: 14268 HPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVG 14327
Query: 434 PNIW---NPQPSQMNRIKIRDTSQASAQHQLWKQSQDSRPRPEP-------------CPP 477
W N +P + + K+ + ++ L ++ ++ EP C P
Sbjct: 14328 TEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKP 14387
Query: 478 PEPSAPQDGVPAENGLPQGDPEPLPPVPKP--------RTVPVADVLARDSSDIGWVLEL 529
D + E G P P VP P + V +D L + I LE+
Sbjct: 14388 TIDLETHDIIVIE-GEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEV 14446
Query: 530 PK 531
PK
Sbjct: 14447 PK 14448
Score = 30.4 bits (67), Expect = 7.0
Identities = 30/135 (22%), Positives = 53/135 (39%), Gaps = 24/135 (17%)
Query: 413 TWVEPDPEPGSDILGYI---NIIDPNIW---NPQPSQMNRIKIRDTSQASAQHQLWKQSQ 466
TW P+ + GS + GYI + + W N P M R + ++ +++ +
Sbjct: 29951 TWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTE-GLEYEHRVTAI 30009
Query: 467 DSRPRPEPCPPPEPSAPQDGVPAENGLPQGDPEPLPPVPKPRTVPVADVLARDSSDIGWV 526
++R +P P +P D P+ P KP+ V D R S + W
Sbjct: 30010 NARGSGKPSRPSKPIVAMD--------------PIAPPGKPQNPRVTDT-TRTSVSLAW- 30053
Query: 527 LELPKEEAPQNGTDH 541
+P++E T +
Sbjct: 30054 -SVPEDEGGSKVTGY 30067
Score = 30.0 bits (66), Expect = 9.1
Identities = 46/195 (23%), Positives = 72/195 (36%), Gaps = 24/195 (12%)
Query: 315 IPMEKEPEPEPIVLPSVVPLVPAGTVAKKLVNPKYALVKAKSVDEIAKISSEKQEAKKPL 374
+ + K EP P V +P PA + PK A V E+ K +++ P+
Sbjct: 9276 VAISKRVEPPPKV--PELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPV 9333
Query: 375 GLKGPALAEHPGELPELLPPIHPGLLHLERANMFEYLPTWVEPDPEPGSDILGYINIIDP 434
K PA E+P+ P+ + + A E P V P+ + G I I+
Sbjct: 9334 PKKEPAAPPKVPEVPK--KPVPEEKIPVPVAKKKEAPPAKV-PEVQKGVVTEEKITIVTQ 9390
Query: 435 NIWNPQPSQMNRIKIRDTSQASAQHQLWKQSQDSRPRPE-----PCPPPEPSAPQDGVPA 489
+P P A + K ++ +P P P PP P+ P+ VP
Sbjct: 9391 REESPPP-------------AVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPE 9437
Query: 490 EN-GLPQGDPEPLPP 503
E +P + PP
Sbjct: 9438 EKVAVPVPVAKKAPP 9452
Score = 30.0 bits (66), Expect = 9.1
Identities = 18/60 (30%), Positives = 27/60 (45%), Gaps = 2/60 (3%)
Query: 370 AKKPLGLKGPALAEHPGELPELLPPIHPGLLHLERANMFEYLPTWVEPDPEPGSDILGYI 429
A G+ PA P ++ E PP+ PG + L W +P+ + GS I GY+
Sbjct: 25274 ASNEYGIGLPAETTEPVKVSE--PPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYV 25331
>gi|169213235 PREDICTED: hypothetical protein [Homo sapiens]
Length = 308
Score = 41.6 bits (96), Expect = 0.003
Identities = 62/239 (25%), Positives = 85/239 (35%), Gaps = 46/239 (19%)
Query: 590 LSDQDSHSGSSGRGPGPRRPSVASSVSEEYFEVREHSVPLRRRHSEQVANGPTPPPRRQL 649
L + S SG +G R + A S ++ R P R S GP PPR
Sbjct: 101 LGRRASCSGRAGSAGRLRCSAAALSAAQRGGPARAQVPPALRTFSP----GPASPPRAS- 155
Query: 650 SAPHITRGTFVGPQGGSPWAQSRGREEADALKRMQAQR-----STDKEAQGQQFHHHRVP 704
GG P +++RGR A+ +R+ S + ++F H+ P
Sbjct: 156 -------------PGGRPGSEARGRSGAECARRVPLHHGPPGASGVGSERDRKFQLHQTP 202
Query: 705 ASGTRDKDGFPGPPRYRSAADSVQSSTRNAGPAMAG----PHHWQAKGGQVPRLLPDPGS 760
A G FPG + TR GP + H W G R L + G
Sbjct: 203 ARG----PPFPG----------ISGMTR--GPVVLSGVNRQHRW-PPGASPSRSLGEAGG 245
Query: 761 PRLAQN-ARPMTDGRATEEHPSPFGIPYSKLSQSKHLKARTGGSQWASSDSKRRAQAPR 818
R A+ RP GRA P GIP + A GG + +S R +PR
Sbjct: 246 ERPARALRRPRAPGRAGGGGPPGGGIPACSIGPGLARLAALGGLP-SILESSRLLPSPR 303
>gi|169212744 PREDICTED: hypothetical protein [Homo sapiens]
Length = 308
Score = 41.6 bits (96), Expect = 0.003
Identities = 62/239 (25%), Positives = 85/239 (35%), Gaps = 46/239 (19%)
Query: 590 LSDQDSHSGSSGRGPGPRRPSVASSVSEEYFEVREHSVPLRRRHSEQVANGPTPPPRRQL 649
L + S SG +G R + A S ++ R P R S GP PPR
Sbjct: 101 LGRRASCSGRAGSAGRLRCSAAALSAAQRGGPARAQVPPALRTFSP----GPASPPRAS- 155
Query: 650 SAPHITRGTFVGPQGGSPWAQSRGREEADALKRMQAQR-----STDKEAQGQQFHHHRVP 704
GG P +++RGR A+ +R+ S + ++F H+ P
Sbjct: 156 -------------PGGRPGSEARGRSGAECARRVPLHHGPPGASGVGSERDRKFQLHQTP 202
Query: 705 ASGTRDKDGFPGPPRYRSAADSVQSSTRNAGPAMAG----PHHWQAKGGQVPRLLPDPGS 760
A G FPG + TR GP + H W G R L + G
Sbjct: 203 ARG----PPFPG----------ISGMTR--GPVVLSGVNRQHRW-PPGASPSRSLGEAGG 245
Query: 761 PRLAQN-ARPMTDGRATEEHPSPFGIPYSKLSQSKHLKARTGGSQWASSDSKRRAQAPR 818
R A+ RP GRA P GIP + A GG + +S R +PR
Sbjct: 246 ERPARALRRPRAPGRAGGGGPPGGGIPACSIGPGLARLAALGGLP-SILESSRLLPSPR 303
>gi|182507165 thymus expressed gene 3-like [Homo sapiens]
Length = 629
Score = 41.6 bits (96), Expect = 0.003
Identities = 59/224 (26%), Positives = 82/224 (36%), Gaps = 29/224 (12%)
Query: 440 QPSQMNRIKIRDTSQASAQHQLWKQSQDSRPRPEPCPPPEPSAPQDGVPAENGLPQGDPE 499
+PS + R+ TS A A + W S +S PEP PP +P D PAE L +
Sbjct: 304 EPS-LERVGGHPTSPA-ALSRAWASSWESEAAPEPAAPPAAPSPPDS-PAEGRLVKAQYI 360
Query: 500 P--------LPPVPKPRTVPVADVLARDSSDIGWVLELPKEEAPQ-NGTDHRLPRMAGPG 550
P LP R P L R S V + P E P+ G R+ +G
Sbjct: 361 PGAQAATRGLPGRAARRKPP---PLTRGRS----VEQSPPRERPRAAGRRGRMAEASGRR 413
Query: 551 HAPLQRQLSVTQDDPESLG--VGLPNGLDGVEEEDDDDYVTLSDQDSHSGSSGRGPGPRR 608
+P R+ S +Q + LG +P+G Y T ++ RGP P
Sbjct: 414 GSPRARKASRSQSETSLLGRASAVPSG--------PPKYPTAEREEPRPPRPRRGPAPTL 465
Query: 609 PSVASSVSEEYFEVREHSVPLRRRHSEQVANGPTPPPRRQLSAP 652
+ A+ + E RR + P P SAP
Sbjct: 466 AAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGPGPSPSAP 509
>gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens]
Length = 380
Score = 41.2 bits (95), Expect = 0.004
Identities = 18/36 (50%), Positives = 19/36 (52%)
Query: 470 PRPEPCPPPEPSAPQDGVPAENGLPQGDPEPLPPVP 505
P P P PPP P P GVPA G P P PP+P
Sbjct: 176 PPPPPGPPPPPGLPPSGVPAAAHGAGGGPPPAPPLP 211
>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
Length = 962
Score = 41.2 bits (95), Expect = 0.004
Identities = 88/388 (22%), Positives = 133/388 (34%), Gaps = 75/388 (19%)
Query: 438 NPQPSQMNRIKIRDTSQASAQHQLWKQSQDSRPRP--EPCPPPEPSAPQDGVPAENGLPQ 495
N + S+M R+ R S++ + + +++ +P E P PS+ Q V + G
Sbjct: 234 NQRSSKMRRLSSRAQSESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEP 293
Query: 496 GDPEPLPPVPKPRTVPVADVLARDSSDIGWVLELPKEEAPQNGTDHRLPRMAGPGHAPLQ 555
G P PLPP P + SS + +E + P +A P AP
Sbjct: 294 GPPAPLPP---PGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTL 350
Query: 556 RQLSVTQDDPESLGVGLPN-GLDGVEEE-------------DDDDYVTLSDQDSHSG--- 598
R +P S G PN G DG +++ D + V + +D S
Sbjct: 351 RV------EPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPT 404
Query: 599 --SSGRGPGPRRPSVASSVSEEYFEVREHSVPLRRRHSEQVANGPTPPPRRQLSAPHITR 656
G P A+S + + E SVP PTPP +
Sbjct: 405 AIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAE--------PTPP---------VLP 447
Query: 657 GTFVGPQGGSPWAQSRGREEADALKRMQAQRSTDKEAQGQQFHHHRVPASGTRDKDGFPG 716
GP G +P E +A + T+ E G + PA P
Sbjct: 448 DEEKGPPGPAP------EPEREAETEPERGAGTEPERIGTE--PSTAPA---------PS 490
Query: 717 PPRYRSAADSVQSSTRNAGPAMAGPHHWQAKGGQVPRLLPDPGSPRLAQNARPMTDGRAT 776
PP +S + + + GPA + P + P + P PGS A+ A P
Sbjct: 491 PPAPKSCLKH-RPAAASEGPAASPP----LAAAESPPVEPGPGSLD-AEAAAPERPKAER 544
Query: 777 EEHPSPFGIPYSKLSQSKHLKARTGGSQ 804
E P P + KA GG++
Sbjct: 545 AEAP-----PAGAERAAPERKAERGGAE 567
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.133 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,991,663
Number of Sequences: 37866
Number of extensions: 2455167
Number of successful extensions: 15729
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 148
Number of HSP's successfully gapped in prelim test: 516
Number of HSP's that attempted gapping in prelim test: 11768
Number of HSP's gapped (non-prelim): 3519
length of query: 823
length of database: 18,247,518
effective HSP length: 111
effective length of query: 712
effective length of database: 14,044,392
effective search space: 9999607104
effective search space used: 9999607104
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.