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Search of human proteins with 223634014
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223634014 solute carrier organic anion transporter family,
member 2B1 isoform 3 [Homo sapiens]
(565 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223634014 solute carrier organic anion transporter family, me... 1143 0.0
gi|223634012 solute carrier organic anion transporter family, me... 1133 0.0
gi|6005820 solute carrier organic anion transporter family, memb... 1133 0.0
gi|188528663 solute carrier organic anion transporter family, me... 405 e-113
gi|222831573 solute carrier organic anion transporter family, me... 293 2e-79
gi|222831575 solute carrier organic anion transporter family, me... 293 4e-79
gi|8394291 solute carrier organic anion transporter family, memb... 270 3e-72
gi|225637473 solute carrier organic anion transporter family, me... 268 8e-72
gi|9790233 solute carrier organic anion transporter family, memb... 265 1e-70
gi|225543525 solute carrier organic anion transporter family, me... 258 1e-68
gi|225543118 solute carrier organic anion transporter family, me... 258 1e-68
gi|225543114 solute carrier organic anion transporter family, me... 258 1e-68
gi|10835099 organic anion transporting polypeptide A [Homo sapiens] 253 4e-67
gi|19913403 organic anion transporting polypeptide A [Homo sapiens] 253 4e-67
gi|116812593 liver-specific organic anion transporter 3TM12 [Hom... 245 7e-65
gi|38679890 solute carrier organic anion transporter family, mem... 238 8e-63
gi|39777594 solute carrier organic anion transporter family memb... 233 3e-61
gi|225543116 solute carrier organic anion transporter family, me... 233 5e-61
gi|225637477 solute carrier organic anion transporter family, me... 208 1e-53
gi|93277099 solute carrier organic anion transporter family, mem... 176 4e-44
gi|225637475 solute carrier organic anion transporter family, me... 135 1e-31
gi|186928854 mitochondrial ribosomal protein S31 [Homo sapiens] 33 0.91
gi|160420317 filamin A, alpha isoform 2 [Homo sapiens] 31 2.6
gi|116063573 filamin A, alpha isoform 1 [Homo sapiens] 31 2.6
gi|148727298 keratin associated protein 10-6 [Homo sapiens] 31 3.5
gi|4504093 G protein-coupled receptor 32 [Homo sapiens] 30 4.5
gi|26051246 tumor necrosis factor ligand superfamily, member 13 ... 30 5.9
gi|4507599 tumor necrosis factor ligand superfamily, member 13 i... 30 5.9
gi|26051248 tumor necrosis factor ligand superfamily, member 13 ... 30 5.9
gi|31083174 interleukin 21 receptor precursor [Homo sapiens] 30 5.9
>gi|223634014 solute carrier organic anion transporter family,
member 2B1 isoform 3 [Homo sapiens]
Length = 565
Score = 1143 bits (2957), Expect = 0.0
Identities = 565/565 (100%), Positives = 565/565 (100%)
Query: 1 MGPRIEDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGV 60
MGPRIEDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGV
Sbjct: 1 MGPRIEDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGV 60
Query: 61 PIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGIS 120
PIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGIS
Sbjct: 61 PIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGIS 120
Query: 121 LTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARK 180
LTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARK
Sbjct: 121 LTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARK 180
Query: 181 GKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLS 240
GKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLS
Sbjct: 181 GKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLS 240
Query: 241 SMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGA 300
SMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGA
Sbjct: 241 SMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGA 300
Query: 301 LCLLGMLLCLFFSLPLFFIGCSSHQIAGITHQTSAHPGLELSPSCMEACSCPLDGFNPVC 360
LCLLGMLLCLFFSLPLFFIGCSSHQIAGITHQTSAHPGLELSPSCMEACSCPLDGFNPVC
Sbjct: 301 LCLLGMLLCLFFSLPLFFIGCSSHQIAGITHQTSAHPGLELSPSCMEACSCPLDGFNPVC 360
Query: 361 DPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVVEGNPVLAGSCDSTCSHLVVPF 420
DPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVVEGNPVLAGSCDSTCSHLVVPF
Sbjct: 361 DPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVVEGNPVLAGSCDSTCSHLVVPF 420
Query: 421 LLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDT 480
LLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDT
Sbjct: 421 LLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDT 480
Query: 481 TCVHWALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEARTKE 540
TCVHWALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEARTKE
Sbjct: 481 TCVHWALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEARTKE 540
Query: 541 SRSSPAVEQQLLVSGPGKKPEDSRV 565
SRSSPAVEQQLLVSGPGKKPEDSRV
Sbjct: 541 SRSSPAVEQQLLVSGPGKKPEDSRV 565
>gi|223634012 solute carrier organic anion transporter family,
member 2B1 isoform 2 [Homo sapiens]
Length = 687
Score = 1133 bits (2930), Expect = 0.0
Identities = 560/560 (100%), Positives = 560/560 (100%)
Query: 6 EDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPF 65
EDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPF
Sbjct: 128 EDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPF 187
Query: 66 GISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKD 125
GISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKD
Sbjct: 188 GISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKD 247
Query: 126 PRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSP 185
PRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSP
Sbjct: 248 PRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSP 307
Query: 186 SKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAG 245
SKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAG
Sbjct: 308 SKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAG 367
Query: 246 MATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLG 305
MATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLG
Sbjct: 368 MATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLG 427
Query: 306 MLLCLFFSLPLFFIGCSSHQIAGITHQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTR 365
MLLCLFFSLPLFFIGCSSHQIAGITHQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTR
Sbjct: 428 MLLCLFFSLPLFFIGCSSHQIAGITHQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTR 487
Query: 366 VEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVVEGNPVLAGSCDSTCSHLVVPFLLLVS 425
VEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVVEGNPVLAGSCDSTCSHLVVPFLLLVS
Sbjct: 488 VEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVVEGNPVLAGSCDSTCSHLVVPFLLLVS 547
Query: 426 LGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHW 485
LGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHW
Sbjct: 548 LGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHW 607
Query: 486 ALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEARTKESRSSP 545
ALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEARTKESRSSP
Sbjct: 608 ALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEARTKESRSSP 667
Query: 546 AVEQQLLVSGPGKKPEDSRV 565
AVEQQLLVSGPGKKPEDSRV
Sbjct: 668 AVEQQLLVSGPGKKPEDSRV 687
>gi|6005820 solute carrier organic anion transporter family, member
2B1 isoform 1 [Homo sapiens]
Length = 709
Score = 1133 bits (2930), Expect = 0.0
Identities = 560/560 (100%), Positives = 560/560 (100%)
Query: 6 EDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPF 65
EDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPF
Sbjct: 150 EDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPF 209
Query: 66 GISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKD 125
GISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKD
Sbjct: 210 GISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKD 269
Query: 126 PRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSP 185
PRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSP
Sbjct: 270 PRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSP 329
Query: 186 SKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAG 245
SKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAG
Sbjct: 330 SKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAG 389
Query: 246 MATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLG 305
MATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLG
Sbjct: 390 MATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLG 449
Query: 306 MLLCLFFSLPLFFIGCSSHQIAGITHQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTR 365
MLLCLFFSLPLFFIGCSSHQIAGITHQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTR
Sbjct: 450 MLLCLFFSLPLFFIGCSSHQIAGITHQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTR 509
Query: 366 VEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVVEGNPVLAGSCDSTCSHLVVPFLLLVS 425
VEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVVEGNPVLAGSCDSTCSHLVVPFLLLVS
Sbjct: 510 VEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVVEGNPVLAGSCDSTCSHLVVPFLLLVS 569
Query: 426 LGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHW 485
LGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHW
Sbjct: 570 LGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHW 629
Query: 486 ALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEARTKESRSSP 545
ALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEARTKESRSSP
Sbjct: 630 ALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEARTKESRSSP 689
Query: 546 AVEQQLLVSGPGKKPEDSRV 565
AVEQQLLVSGPGKKPEDSRV
Sbjct: 690 AVEQQLLVSGPGKKPEDSRV 709
>gi|188528663 solute carrier organic anion transporter family,
member 2A1 [Homo sapiens]
Length = 643
Score = 405 bits (1041), Expect = e-113
Identities = 213/524 (40%), Positives = 318/524 (60%), Gaps = 59/524 (11%)
Query: 10 QDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISY 69
QD S C TT P S S+ G+M VAQ L G+G VPIQPFGISY
Sbjct: 148 QDLPPSKCHSTTQNPQKETS-------------SMWGLMVVAQLLAGIGTVPIQPFGISY 194
Query: 70 IDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWV 129
+DDF+ SNSPLY+ ILFA+++ GP + LGS+ML+++VD ++ ++L DPRW+
Sbjct: 195 VDDFSEPSNSPLYISILFAISVFGPAFGYLLGSVMLQIFVDYGRVNTAAVNLVPGDPRWI 254
Query: 130 GAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQS 189
GAWWLG LI++ + L + P+FFFP+ MP K T ARK +++ S+ S
Sbjct: 255 GAWWLGLLISSALLVLTSFPFFFFPRAMP-------IGAKRAPATADEARKLEEAKSRGS 307
Query: 190 PGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATF 249
++ FIK FP + L+ L + +F+LVVL+Q SS+ AG++TF
Sbjct: 308 -------------------LVDFIKRFPCIFLRLLMNSLFVLVVLAQCTFSSVIAGLSTF 348
Query: 250 LPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKR----LHLGPVGCGALCLLG 305
L KFLE+Q+ +A+YAN LIG ++ P+ +G++ GG+L+KR L P + +
Sbjct: 349 LNKFLEKQYGTSAAYANFLIGAVNLPAAALGMLFGGILMKRFVFSLQAIPRIATTIITIS 408
Query: 306 MLLCLFFSLPLFFIGCSSHQIAGI---THQTSAHPGLELSPSCMEACSCPLDGFNPVCDP 362
M+LC +PLFF+GCS+ +A + + +S HP SP+C CSCP F+PVC
Sbjct: 409 MILC----VPLFFMGCSTPTVAEVYPPSTSSSIHP---QSPACRRDCSCPDSIFHPVCG- 460
Query: 363 STRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVVEGN-PVLAGSCDSTCSHLVVPFL 421
+EY++PCHAGCS+ + + + Q+ Y NCSCV G+ GSC C+H ++P +
Sbjct: 461 DNGIEYLSPCHAGCSN-INMSSATSKQLIYLNCSCVTGGSASAKTGSCPVPCAHFLLPAI 519
Query: 422 LLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTT 481
L+S S +AC++H P +M++LR V +E+K+ A+G+QF+ +R+LAW+PSP ++G ID +
Sbjct: 520 FLISFVSLIACISHNPLYMMVLRVVNQEEKSFAIGVQFLLMRLLAWLPSPALYGLTIDHS 579
Query: 482 CVHW-ALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGS--VICF 522
C+ W +L GRR C YY+ND LR+R++GLQ +K ++CF
Sbjct: 580 CIRWNSLCLGRRGACAYYDNDALRDRYLGLQMGYKALGMLLLCF 623
>gi|222831573 solute carrier organic anion transporter family,
member 3A1 isoform 2 [Homo sapiens]
Length = 692
Score = 293 bits (751), Expect = 2e-79
Identities = 167/528 (31%), Positives = 273/528 (51%), Gaps = 44/528 (8%)
Query: 37 TETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGL 96
T +L ++G AQ LLG+G P+QP G+SYIDD +S LY+GILF + + GP
Sbjct: 173 TNMMYLLLIG----AQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGILFTMLVFGPAC 228
Query: 97 AFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKE 156
F LGS ++YVD + + +T DPRW+GAWW GFL+ + +++ F FP+
Sbjct: 229 GFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFSSLLMFGFPQS 288
Query: 157 MPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQ--IAP--NLTVIQF 212
+P PA + + + + E K +G+++ + P + + Q
Sbjct: 289 LPPH--------------SEPAMESEQAMLSEREYERPKPSNGVLRHPLEPDSSASCFQQ 334
Query: 213 IKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCL 272
++V P+V L +P+F ++L+ ++ AG A FL K+LE+QF++T S AN L+G
Sbjct: 335 LRVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMT 394
Query: 273 SFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGIT-- 330
+ P +GI +GG+LVK+L L +G + +L L+ + F+GC + +AG+T
Sbjct: 395 AIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVP 454
Query: 331 HQTSAHPGLELSP--SCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNS 388
+ S PG L P C C C D F PVC + + Y++ C AGC+S
Sbjct: 455 YGNSTAPGSALDPYSPCNNNCECQTDSFTPVCG-ADGITYLSACFAGCNS---------- 503
Query: 389 QVFYTNCSCV----VEGNPVLAGSCDST-CSHLVVPFLLLVSLGSALACLTHTPSFMLIL 443
T C+C+ E V+ G C S C + FL ++ + S + + TPS ++++
Sbjct: 504 -TNLTGCACLTTVPAENATVVPGKCPSPGCQEAFLTFLCVMCICSLIGAMAQTPSVIILI 562
Query: 444 RGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWALSCGRRAVCRYYNNDLL 503
R V E K+ A+G+ F+ LR+L ++P P+I G+ ID+TC+ W+ CG + C Y+N +
Sbjct: 563 RTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWSTFCGEQGACVLYDNVVY 622
Query: 504 RNRFIGLQFFFKTGSVICFALVLAVLRQQDKE-ARTKESRSSPAVEQQ 550
R ++ + K+ + I + LR+ K + E S + E Q
Sbjct: 623 RYLYVSIAIALKSFAFILYTTTWQCLRKNYKRYIKNHEGGLSTSTEYQ 670
>gi|222831575 solute carrier organic anion transporter family,
member 3A1 isoform 1 [Homo sapiens]
Length = 710
Score = 293 bits (749), Expect = 4e-79
Identities = 163/511 (31%), Positives = 267/511 (52%), Gaps = 43/511 (8%)
Query: 37 TETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGL 96
T +L ++G AQ LLG+G P+QP G+SYIDD +S LY+GILF + + GP
Sbjct: 173 TNMMYLLLIG----AQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGILFTMLVFGPAC 228
Query: 97 AFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKE 156
F LGS ++YVD + + +T DPRW+GAWW GFL+ + +++ F FP+
Sbjct: 229 GFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFSSLLMFGFPQS 288
Query: 157 MPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQ--IAP--NLTVIQF 212
+P PA + + + + E K +G+++ + P + + Q
Sbjct: 289 LPPH--------------SEPAMESEQAMLSEREYERPKPSNGVLRHPLEPDSSASCFQQ 334
Query: 213 IKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCL 272
++V P+V L +P+F ++L+ ++ AG A FL K+LE+QF++T S AN L+G
Sbjct: 335 LRVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMT 394
Query: 273 SFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGIT-- 330
+ P +GI +GG+LVK+L L +G + +L L+ + F+GC + +AG+T
Sbjct: 395 AIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVP 454
Query: 331 HQTSAHPGLELSP--SCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNS 388
+ S PG L P C C C D F PVC + + Y++ C AGC+S
Sbjct: 455 YGNSTAPGSALDPYSPCNNNCECQTDSFTPVCG-ADGITYLSACFAGCNS---------- 503
Query: 389 QVFYTNCSCV----VEGNPVLAGSCDST-CSHLVVPFLLLVSLGSALACLTHTPSFMLIL 443
T C+C+ E V+ G C S C + FL ++ + S + + TPS ++++
Sbjct: 504 -TNLTGCACLTTVPAENATVVPGKCPSPGCQEAFLTFLCVMCICSLIGAMAQTPSVIILI 562
Query: 444 RGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWALSCGRRAVCRYYNNDLL 503
R V E K+ A+G+ F+ LR+L ++P P+I G+ ID+TC+ W+ CG + C Y+N +
Sbjct: 563 RTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWSTFCGEQGACVLYDNVVY 622
Query: 504 RNRFIGLQFFFKTGSVICFALVLAVLRQQDK 534
R ++ + K+ + I + LR+ K
Sbjct: 623 RYLYVSIAIALKSFAFILYTTTWQCLRKNYK 653
>gi|8394291 solute carrier organic anion transporter family, member
1C1 isoform 2 [Homo sapiens]
Length = 712
Score = 270 bits (690), Expect = 3e-72
Identities = 155/498 (31%), Positives = 259/498 (52%), Gaps = 35/498 (7%)
Query: 48 MFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRL 107
+F+ L G+G PIQP GI+Y+DDFA N+ Y+G + V ++GP F LGSL +L
Sbjct: 190 VFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKL 249
Query: 108 YVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFR 167
YVDI + I++T KDP+WVGAWWLG+LIA LAA+P+++ PK +P+
Sbjct: 250 YVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPR-------- 301
Query: 168 RKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHP 227
S +R+ +S S++S D N +++ + F L +P
Sbjct: 302 --------SQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNP 353
Query: 228 IFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVL 287
++ L + + + GM T+ PK++E+Q+ ++S AN +IG ++ P+V +GI GG++
Sbjct: 354 VYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIV 413
Query: 288 VKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGIT-----HQTSAHPGLELS 342
+K+ + G L L + L LF +GC + +AG+T + ++ L
Sbjct: 414 MKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALF 473
Query: 343 PSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCV---- 398
C C C + P+C + Y++ C AGC + + + NC+CV
Sbjct: 474 SDCNSRCKCSETKWEPMCG-ENGITYVSACLAGCQT----SNRSGKNIIFYNCTCVGIAA 528
Query: 399 -VEGNPV-LAGSC--DSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLA 454
GN + G C D+ C + + FL++ + S L P ++L+LR +K + K+ A
Sbjct: 529 SKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFA 588
Query: 455 VGIQFMFLRILAWMPSPVIHGSAIDTTCVHWALS-CGRRAVCRYYNNDLLRNRFIGLQFF 513
+GI + +R+LA +P+PV G IDT+C+ W CG R CR Y++++ R+ ++GL
Sbjct: 589 LGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVI 648
Query: 514 FKTGSVICFALVLAVLRQ 531
T S++ VL +L++
Sbjct: 649 LGTVSILLSIAVLFILKK 666
>gi|225637473 solute carrier organic anion transporter family,
member 5A1 isoform 1 [Homo sapiens]
Length = 848
Score = 268 bits (686), Expect = 8e-72
Identities = 174/568 (30%), Positives = 267/568 (47%), Gaps = 67/568 (11%)
Query: 25 ASAPSNGNCSSYTET---------------QHLSVVGIMFVAQTLLGVGGVPIQPFGISY 69
ASAP++G C T H V + AQ L+G+G PI G +Y
Sbjct: 229 ASAPNDGLCQGGNSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTY 288
Query: 70 IDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWV 129
+DD NS LYL I++ + +GP + + LG L++ YVD P + L DPR++
Sbjct: 289 LDDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFI 344
Query: 130 GAWWLGFLIAAGAVALAAIPYFFFPKEMP-KEKRELQFRRKVLAVTDSPARKGKDSPSKQ 188
G WW GFL+ A A+ L P F FPK++P + K++ + + V AV+D K K + S+Q
Sbjct: 345 GNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQ 404
Query: 189 SPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMAT 248
+ + + G + ++ PR ++ L + FL V LS S++ T
Sbjct: 405 ADKKVSSMGFG-----------KDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFIT 453
Query: 249 FLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLL 308
F+PKF+E QF I AS A++ G + PS VGIV+GG ++K+L LG L ++ +
Sbjct: 454 FIPKFIESQFGIPASNASIYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGV 513
Query: 309 CLFFSLPLFFIGCSSHQIAGITHQTSAHPGL-----ELSPSCMEACSCPLDGFNPVCDPS 363
L LF +GC S + GI + P L L+ SC C C + + PVC S
Sbjct: 514 SLLCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCG-S 572
Query: 364 TRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVV------------------------ 399
+ Y PC AGC V L YT C+CV
Sbjct: 573 DGITYFNPCLAGC---VNSGNLSTGIRNYTECTCVQSRQVITPPTVGQRSQLRVVIVKTY 629
Query: 400 --EGNPVLAGSCDSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGI 457
E ++G C TC+ L+ PFL+ + + + + + ++ LR V+ E++ A+G+
Sbjct: 630 LNENGYAVSGKCKRTCNTLI-PFLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGM 688
Query: 458 QFMFLRILAWMPSPVIHGSAIDTTCVHWALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTG 517
QF+ LR LA++P+P+ G+ IDTTC+ W CG + C YN R + GL K
Sbjct: 689 QFVLLRTLAYIPTPIYFGAVIDTTCMLWQQECGVQGSCWEYNVTSFRFVYFGLAAGLKFV 748
Query: 518 SVICFALVLAVLRQQDKEARTKESRSSP 545
I L ++ ++ + + R P
Sbjct: 749 GFIFIFLAWYSIKYKEDGLQRRRQREFP 776
>gi|9790233 solute carrier organic anion transporter family, member
1B3 [Homo sapiens]
Length = 702
Score = 265 bits (676), Expect = 1e-70
Identities = 165/511 (32%), Positives = 264/511 (51%), Gaps = 42/511 (8%)
Query: 48 MFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRL 107
+F+ L G+G PI P GISYIDDFA +S LYLG L A+ M+GP + F LGSL ++
Sbjct: 174 VFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKM 233
Query: 108 YVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPK--EMPKEKRELQ 165
YVDI + I +T KD RWVGAWWLGFL++ +++IP+FF PK P+++R++
Sbjct: 234 YVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKNPNKPQKERKIS 293
Query: 166 FRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLR 225
VL D + + + G++ K V F + +L L
Sbjct: 294 LSLHVLKTNDD----RNQTANLTNQGKNVTK-----------NVTGFFQSLKSILTNPL- 337
Query: 226 HPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGG 285
+ IFLL+ L QV S G T++ K++E+Q+ +AS+AN L+G ++ P+V G+ +GG
Sbjct: 338 YVIFLLLTLLQV---SSFIGSFTYVFKYMEQQYGQSASHANFLLGIITIPTVATGMFLGG 394
Query: 286 VLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGIT------HQTSAHPGL 339
++K+ L VG L ++ F L F + C S +AG+T + ++H +
Sbjct: 395 FIIKKFKLSLVGIAKFSFLTSMISFLFQLLYFPLICESKSVAGLTLTYDGNNSVASHVDV 454
Query: 340 ELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVV 399
LS C C+C + PVC + + Y++PC AGC S + VFY NCSCV
Sbjct: 455 PLS-YCNSECNCDESQWEPVCG-NNGITYLSPCLAGCKS---SSGIKKHTVFY-NCSCVE 508
Query: 400 ------EGNPVLAGSC--DSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVKKEDK 451
G C D+TC+ ++ + + S + T +L ++ V+ E K
Sbjct: 509 VTGLQNRNYSAHLGECPRDNTCTRKFFIYVAIQVINSLFSATGGTTFILLTVKIVQPELK 568
Query: 452 TLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWAL-SCGRRAVCRYYNNDLLRNRFIGL 510
LA+G Q M +R L + +P+ G+ ID TC+ W+ SCG + CR YN+ ++GL
Sbjct: 569 ALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKWSTNSCGAQGACRIYNSVFFGRVYLGL 628
Query: 511 QFFFKTGSVICFALVLAVLRQQDKEARTKES 541
+ +++ + + + ++++ + TK S
Sbjct: 629 SIALRFPALVLYIVFIFAMKKKFQGKDTKAS 659
>gi|225543525 solute carrier organic anion transporter family,
member 1B1 [Homo sapiens]
Length = 691
Score = 258 bits (659), Expect = 1e-68
Identities = 162/526 (30%), Positives = 266/526 (50%), Gaps = 46/526 (8%)
Query: 48 MFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRL 107
+F+ L G+G PI P G+SYIDDFA +S LYLGIL A+ M+GP + F LGSL ++
Sbjct: 174 VFMGNMLRGIGETPIVPLGLSYIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKM 233
Query: 108 YVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPK--EMPKEKRELQ 165
YVDI + I +T D RWVGAWWL FL++ +++IP+FF P+ P+++R+
Sbjct: 234 YVDIGYVDLSTIRITPTDSRWVGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKAS 293
Query: 166 FRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAPNLT--VIQFIKVFPRVLLQT 223
VL D KD + L N+T V F + F +
Sbjct: 294 LSLHVLETNDE-----KDQTA------------NLTNQGKNITKNVTGFFQSFKSI---- 332
Query: 224 LRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVV 283
L +P++++ VL + S G T++ K++E+Q+ +S AN+L+G ++ P G+ +
Sbjct: 333 LTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKANILLGVITIPIFASGMFL 392
Query: 284 GGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGIT------HQTSAHP 337
GG ++K+ L VG ++ L F L FFI C + +AG+T + ++H
Sbjct: 393 GGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVAGLTMTYDGNNPVTSHR 452
Query: 338 GLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSC 397
+ LS C C+C + PVC + + YI+PC AGC S + + + + NCSC
Sbjct: 453 DVPLS-YCNSDCNCDESQWEPVCG-NNGITYISPCLAGCKS----SSGNKKPIVFYNCSC 506
Query: 398 VV------EGNPVLAGSC--DSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVKKE 449
+ G C D C+ F+ + L + L T MLI++ V+ E
Sbjct: 507 LEVTGLQNRNYSAHLGECPRDDACTRKFYFFVAIQVLNLFFSALGGTSHVMLIVKIVQPE 566
Query: 450 DKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWAL-SCGRRAVCRYYNNDLLRNRFI 508
K+LA+G M +R L + +P+ G+ IDTTC+ W+ +CG R CR YN+ ++
Sbjct: 567 LKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWSTNNCGTRGSCRTYNSTSFSRVYL 626
Query: 509 GLQFFFKTGSVICFALVLAVLRQQDKEARTKESRSSPAVEQQLLVS 554
GL + S++ + +++ ++++ +E S + +++ L S
Sbjct: 627 GLSSMLRVSSLVLYIILIYAMKKKYQEKDINASENGSVMDEANLES 672
>gi|225543118 solute carrier organic anion transporter family,
member 1C1 isoform 1 [Homo sapiens]
Length = 730
Score = 258 bits (659), Expect = 1e-68
Identities = 148/471 (31%), Positives = 244/471 (51%), Gaps = 35/471 (7%)
Query: 48 MFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRL 107
+F+ L G+G PIQP GI+Y+DDFA N+ Y+G + V ++GP F LGSL +L
Sbjct: 190 VFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKL 249
Query: 108 YVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFR 167
YVDI + I++T KDP+WVGAWWLG+LIA LAA+P+++ PK +P+
Sbjct: 250 YVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPR-------- 301
Query: 168 RKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHP 227
S +R+ +S S++S D N +++ + F L +P
Sbjct: 302 --------SQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNP 353
Query: 228 IFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVL 287
++ L + + + GM T+ PK++E+Q+ ++S AN +IG ++ P+V +GI GG++
Sbjct: 354 VYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIV 413
Query: 288 VKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGIT-----HQTSAHPGLELS 342
+K+ + G L L + L LF +GC + +AG+T + ++ L
Sbjct: 414 MKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALF 473
Query: 343 PSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCV---- 398
C C C + P+C + Y++ C AGC + + + NC+CV
Sbjct: 474 SDCNSRCKCSETKWEPMCG-ENGITYVSACLAGCQT----SNRSGKNIIFYNCTCVGIAA 528
Query: 399 -VEGNPV-LAGSC--DSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLA 454
GN + G C D+ C + + FL++ + S L P ++L+LR +K + K+ A
Sbjct: 529 SKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFA 588
Query: 455 VGIQFMFLRILAWMPSPVIHGSAIDTTCVHWALS-CGRRAVCRYYNNDLLR 504
+GI + +R+LA +P+PV G IDT+C+ W CG R CR Y++++ R
Sbjct: 589 LGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFR 639
>gi|225543114 solute carrier organic anion transporter family,
member 1C1 isoform 4 [Homo sapiens]
Length = 612
Score = 258 bits (659), Expect = 1e-68
Identities = 148/471 (31%), Positives = 244/471 (51%), Gaps = 35/471 (7%)
Query: 48 MFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRL 107
+F+ L G+G PIQP GI+Y+DDFA N+ Y+G + V ++GP F LGSL +L
Sbjct: 72 VFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKL 131
Query: 108 YVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFR 167
YVDI + I++T KDP+WVGAWWLG+LIA LAA+P+++ PK +P+
Sbjct: 132 YVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPR-------- 183
Query: 168 RKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHP 227
S +R+ +S S++S D N +++ + F L +P
Sbjct: 184 --------SQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNP 235
Query: 228 IFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVL 287
++ L + + + GM T+ PK++E+Q+ ++S AN +IG ++ P+V +GI GG++
Sbjct: 236 VYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIV 295
Query: 288 VKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGIT-----HQTSAHPGLELS 342
+K+ + G L L + L LF +GC + +AG+T + ++ L
Sbjct: 296 MKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALF 355
Query: 343 PSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCV---- 398
C C C + P+C + Y++ C AGC + + + NC+CV
Sbjct: 356 SDCNSRCKCSETKWEPMCG-ENGITYVSACLAGCQT----SNRSGKNIIFYNCTCVGIAA 410
Query: 399 -VEGNPV-LAGSC--DSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLA 454
GN + G C D+ C + + FL++ + S L P ++L+LR +K + K+ A
Sbjct: 411 SKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFA 470
Query: 455 VGIQFMFLRILAWMPSPVIHGSAIDTTCVHWALS-CGRRAVCRYYNNDLLR 504
+GI + +R+LA +P+PV G IDT+C+ W CG R CR Y++++ R
Sbjct: 471 LGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFR 521
>gi|10835099 organic anion transporting polypeptide A [Homo sapiens]
Length = 670
Score = 253 bits (645), Expect = 4e-67
Identities = 153/495 (30%), Positives = 254/495 (51%), Gaps = 41/495 (8%)
Query: 48 MFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRL 107
+ V + G+G PI P GISYI+DFA NSPLY+G++ ++GP + L S +
Sbjct: 161 VLVGNIVRGMGETPILPLGISYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANV 220
Query: 108 YVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFR 167
YVD + + +T D RWVGAWW GFLI AG L AIP+FF P +PKE E
Sbjct: 221 YVDTGFVNTDDLIITPTDTRWVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLE---- 276
Query: 168 RKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHP 227
T++ K ++ ++ E K++ G+ K F + +P
Sbjct: 277 ------TNADIIKNENEDKQKE--EVKKEKYGIT------------KDFLPFMKSLSCNP 316
Query: 228 IFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVL 287
I++L +L V + M +F+PK+LE+Q+ I++S A L+G + P + +G ++GG++
Sbjct: 317 IYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICIGYIIGGLI 376
Query: 288 VKRLHLGPVGCGAL-CLLGMLLCLFFSLPLFFIGCSSHQIAGITHQTSAHP-----GLEL 341
+K+ + + C L +L L + L F + C + + GI P ++
Sbjct: 377 MKKFKITVKQAAHIGCWLSLLEYLLYFLS-FLMTCENSSVVGINTSYEGIPQDLYVENDI 435
Query: 342 SPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCV-VE 400
C C+CP ++PVC + + Y++ C AGC + + + + NCSC+
Sbjct: 436 FADCNVDCNCPSKIWDPVCG-NNGLSYLSACLAGCETSIG----TGINMVFQNCSCIQTS 490
Query: 401 GN-PVLAGSCDS--TCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGI 457
GN + G CD CS ++ FL+L ++ S + L P +M++LR +K E+K+L VG+
Sbjct: 491 GNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGL 550
Query: 458 QFMFLRILAWMPSPVIHGSAIDTTCVHW-ALSCGRRAVCRYYNNDLLRNRFIGLQFFFKT 516
R+ A +P+P+ G+ +D+TC+HW L CG CR Y++ R ++GL +
Sbjct: 551 HTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGLPAALRG 610
Query: 517 GSVICFALVLAVLRQ 531
S + ++L +LR+
Sbjct: 611 SSFVPALIILILLRK 625
Score = 30.0 bits (66), Expect = 5.9
Identities = 22/92 (23%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Query: 228 IFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVL 287
+FLL + +++ + +ERQF+I S + G ++++ I+
Sbjct: 21 MFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLL-IIFVSYF 79
Query: 288 VKRLHLGPVGCGALCLLGMLLCLFFSLPLFFI 319
+LH P+ G C++ L C SLP F +
Sbjct: 80 GTKLH-RPIMIGIGCVVMGLGCFLKSLPHFLM 110
>gi|19913403 organic anion transporting polypeptide A [Homo sapiens]
Length = 670
Score = 253 bits (645), Expect = 4e-67
Identities = 153/495 (30%), Positives = 254/495 (51%), Gaps = 41/495 (8%)
Query: 48 MFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRL 107
+ V + G+G PI P GISYI+DFA NSPLY+G++ ++GP + L S +
Sbjct: 161 VLVGNIVRGMGETPILPLGISYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANV 220
Query: 108 YVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFR 167
YVD + + +T D RWVGAWW GFLI AG L AIP+FF P +PKE E
Sbjct: 221 YVDTGFVNTDDLIITPTDTRWVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLE---- 276
Query: 168 RKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHP 227
T++ K ++ ++ E K++ G+ K F + +P
Sbjct: 277 ------TNADIIKNENEDKQKE--EVKKEKYGIT------------KDFLPFMKSLSCNP 316
Query: 228 IFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVL 287
I++L +L V + M +F+PK+LE+Q+ I++S A L+G + P + +G ++GG++
Sbjct: 317 IYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICIGYIIGGLI 376
Query: 288 VKRLHLGPVGCGAL-CLLGMLLCLFFSLPLFFIGCSSHQIAGITHQTSAHP-----GLEL 341
+K+ + + C L +L L + L F + C + + GI P ++
Sbjct: 377 MKKFKITVKQAAHIGCWLSLLEYLLYFLS-FLMTCENSSVVGINTSYEGIPQDLYVENDI 435
Query: 342 SPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCV-VE 400
C C+CP ++PVC + + Y++ C AGC + + + + NCSC+
Sbjct: 436 FADCNVDCNCPSKIWDPVCG-NNGLSYLSACLAGCETSIG----TGINMVFQNCSCIQTS 490
Query: 401 GN-PVLAGSCDS--TCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGI 457
GN + G CD CS ++ FL+L ++ S + L P +M++LR +K E+K+L VG+
Sbjct: 491 GNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGL 550
Query: 458 QFMFLRILAWMPSPVIHGSAIDTTCVHW-ALSCGRRAVCRYYNNDLLRNRFIGLQFFFKT 516
R+ A +P+P+ G+ +D+TC+HW L CG CR Y++ R ++GL +
Sbjct: 551 HTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGLPAALRG 610
Query: 517 GSVICFALVLAVLRQ 531
S + ++L +LR+
Sbjct: 611 SSFVPALIILILLRK 625
Score = 30.0 bits (66), Expect = 5.9
Identities = 22/92 (23%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Query: 228 IFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVL 287
+FLL + +++ + +ERQF+I S + G ++++ I+
Sbjct: 21 MFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLL-IIFVSYF 79
Query: 288 VKRLHLGPVGCGALCLLGMLLCLFFSLPLFFI 319
+LH P+ G C++ L C SLP F +
Sbjct: 80 GTKLH-RPIMIGIGCVVMGLGCFLKSLPHFLM 110
>gi|116812593 liver-specific organic anion transporter 3TM12 [Homo
sapiens]
Length = 640
Score = 245 bits (626), Expect = 7e-65
Identities = 162/514 (31%), Positives = 252/514 (49%), Gaps = 52/514 (10%)
Query: 48 MFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRL 107
+F+ L G+G PI P GISYIDDFA +S LYLG + + M G AF LGSL ++
Sbjct: 127 VFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFMLGSLFAKM 186
Query: 108 YVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFP--KEMPKEKRELQ 165
YVDI + I +T KD RWVGAWWLGFL++ +++IP+FF P P+++R++
Sbjct: 187 YVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLNPNKPQKERKVS 246
Query: 166 FRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAPNLT-----VIQFIKVFPRVL 220
VL K D QIA NLT + + + F + L
Sbjct: 247 LFLHVL-----------------------KTNDKRNQIA-NLTNRRKYITKNVTGFFQSL 282
Query: 221 LQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVG 280
L +P++++ V+ + S T++ K +E+Q+ +AS N L+G L+ P+V +G
Sbjct: 283 KSILTNPLYVIFVIFTLLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIG 342
Query: 281 IVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGIT------HQTS 334
+ GG ++K+ L VG L + L + FF+ C S +AG+T
Sbjct: 343 MFSGGYIIKKFKLSLVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVR 402
Query: 335 AHPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTN 394
+H + LS C C+C + PVC + + Y++PC AGC S + + + + N
Sbjct: 403 SHVDVPLS-YCNSECNCDESQWEPVCG-NNGITYLSPCLAGCKS----SSGNKEPIVFYN 456
Query: 395 CSCVV------EGNPVLAGSC--DSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGV 446
CSCV + G C D C+ + ++ L + L + T +L++R V
Sbjct: 457 CSCVEVIGLQNKNYSAHLGECPRDDACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIV 516
Query: 447 KKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWAL-SCGRRAVCRYYNNDLLRN 505
+ E K LA+G M +R L + P+ G+ IDTTC+ W+ SCG R CR YN+ L
Sbjct: 517 QPELKALAIGFHSMIMRSLGGILVPIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGR 576
Query: 506 RFIGLQFFFKTGSVICFALVLAVLRQQDKEARTK 539
F GL+ ++ + + V+R++ TK
Sbjct: 577 AFFGLKVALIFPVLVLLTVFIFVVRKKSHGKDTK 610
>gi|38679890 solute carrier organic anion transporter family, member
4C1 [Homo sapiens]
Length = 724
Score = 238 bits (608), Expect = 8e-63
Identities = 159/524 (30%), Positives = 251/524 (47%), Gaps = 50/524 (9%)
Query: 1 MGPRIEDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFV-AQTLLGVGG 59
+G + +PQ F L + + + S + T LS +F+ Q LLG GG
Sbjct: 184 LGALVFSLPQFFSGEYKLGSLFEDTCVTTRNSTSCTSSTSSLSNYLYVFILGQLLLGAGG 243
Query: 60 VPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGI 119
P+ G +++DD S LY+G +A++++GP + + LG +L +Y+D+ M E
Sbjct: 244 TPLYTLGTAFLDDSVPTHKSSLYIGTGYAMSILGPAIGYVLGGQLLTIYIDV-AMGES-T 301
Query: 120 SLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPAR 179
+T DPRW+GAWW+GFL++ IP+ FPK +P E+Q
Sbjct: 302 DVTEDDPRWLGAWWIGFLLSWIFAWSLIIPFSCFPKHLPGTA-EIQ-------------- 346
Query: 180 KGKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCL 239
GK S + QS + K + IK FP L +++ +F+ +VLS
Sbjct: 347 AGKTSQAHQSNSNADVKFG------------KSIKDFPAALKNLMKNAVFMCLVLSTSSE 394
Query: 240 SSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCG 299
+ + G ATFLPKF+E QF +T+S+A L G + P +G ++GG LV + +
Sbjct: 395 ALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQILGGFLVSKFRMTCKNTM 454
Query: 300 ALCLLGMLLCLFFSLPLFFIGCSSHQIAGITHQTSAHPGL-ELSPSCMEACSCPLDGFNP 358
L + L S + C + AG++ + L L C C+C + P
Sbjct: 455 KFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGTGELGNLIAPCNANCNCSRSYYYP 514
Query: 359 VCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVVE-----------GNPVLAG 407
VC V+Y +PC AGCS+ V A +V+Y NCSC+ G AG
Sbjct: 515 VCGDG--VQYFSPCFAGCSNPV---AHRKPKVYY-NCSCIERKTEITSTAETFGFEAKAG 568
Query: 408 SCDSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAW 467
C++ C+ L + FL + + + TP + ILR V ++LA+GIQFM LR+L
Sbjct: 569 KCETHCAKLPI-FLCIFFIVIIFTFMAGTPITVSILRCVNHRQRSLALGIQFMVLRLLGT 627
Query: 468 MPSPVIHGSAIDTTCVHWALS-CGRRAVCRYYNNDLLRNRFIGL 510
+P P+I G ID+TC+ W ++ CG + C Y+N + + + +
Sbjct: 628 IPGPIIFGFTIDSTCILWDINDCGIKGACWIYDNIKMAHMLVAI 671
>gi|39777594 solute carrier organic anion transporter family member
4A1 [Homo sapiens]
Length = 722
Score = 233 bits (595), Expect = 3e-61
Identities = 154/511 (30%), Positives = 252/511 (49%), Gaps = 45/511 (8%)
Query: 26 SAPSNGNCSSYTETQHLSVVGIMFV-AQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLG 84
+ P+N T LS ++F+ Q L GVG P+ G++Y+D+ +S SP+Y+
Sbjct: 207 TCPANPGAVCADSTSGLSRYQLVFMLGQFLHGVGATPLYTLGVTYLDENVKSSCSPVYIA 266
Query: 85 ILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVA 144
I + ++GP + +G +L +Y ++ + E LT + P WVGAWW+GFL + A
Sbjct: 267 IFYTAAILGPAAGYLIGGALLNIYTEMGRRTE----LTTESPLWVGAWWVGFLGSGAAAF 322
Query: 145 LAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIA 204
A+P +P+++P +R R + + KDS S GE++ G
Sbjct: 323 FTAVPILGYPRQLPGSQRYAVMRAAEM-------HQLKDS----SRGEASNPDFG----- 366
Query: 205 PNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASY 264
+ I+ P + L++P F+L+ L+ +++ GM+TF PKFLE QFS++AS
Sbjct: 367 ------KTIRDLPLSIWLLLKNPTFILLCLAGATEATLITGMSTFSPKFLESQFSLSASE 420
Query: 265 ANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSH 324
A L G L P+ G +GG V +L L CL ++ L L +F + C S
Sbjct: 421 AATLFGYLVVPAGGGGTFLGGFFVNKLRLRGSAVIKFCLFCTVVSLLGIL-VFSLHCPSV 479
Query: 325 QIAGITHQTSA----HPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWV 380
+AG+T L L+ C ACSC + ++PVC S + Y + CHAGC +
Sbjct: 480 PMAGVTASYGGSLLPEGHLNLTAPCNAACSCQPEHYSPVCG-SDGLMYFSLCHAGCPA-A 537
Query: 381 VQDALDNSQVFYTNCSCVVEG-----NPVLAGSCDSTCSH--LVVPFLLLVSLGSALACL 433
+ +D +V Y +CSC+ + AG C STC L++ F+ +V + L+ +
Sbjct: 538 TETNVDGQKV-YRDCSCIPQNLSSGFGHATAGKCTSTCQRKPLLLVFIFVVIFFTFLSSI 596
Query: 434 THTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWALSCGRRA 493
P+ LR V+ ++ A+GIQ++ +RIL +P P+ G ID C+ W CG++
Sbjct: 597 ---PALTATLRCVRDPQRSFALGIQWIVVRILGGIPGPIAFGWVIDKACLLWQDQCGQQG 653
Query: 494 VCRYYNNDLLRNRFIGLQFFFKTGSVICFAL 524
C Y N + + + +K V+ FA+
Sbjct: 654 SCLVYQNSAMSRYILIMGLLYKVLGVLFFAI 684
>gi|225543116 solute carrier organic anion transporter family,
member 1C1 isoform 3 [Homo sapiens]
Length = 663
Score = 233 bits (593), Expect = 5e-61
Identities = 140/469 (29%), Positives = 238/469 (50%), Gaps = 35/469 (7%)
Query: 77 SNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGF 136
S S + G + V ++GP F LGSL +LYVDI + I++T KDP+WVGAWWLG+
Sbjct: 170 SKSKISNGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGY 229
Query: 137 LIAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKK 196
LIA LAA+P+++ PK +P+ S +R+ +S S++S
Sbjct: 230 LIAGIISLLAAVPFWYLPKSLPR----------------SQSREDSNSSSEKSKFIIDDH 273
Query: 197 QDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLER 256
D N +++ + F L +P++ L + + + GM T+ PK++E+
Sbjct: 274 TDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQ 333
Query: 257 QFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPL 316
Q+ ++S AN +IG ++ P+V +GI GG+++K+ + G L L + L L
Sbjct: 334 QYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSL 393
Query: 317 FFIGCSSHQIAGIT-----HQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITP 371
F +GC + +AG+T + ++ L C C C + P+C + Y++
Sbjct: 394 FALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCG-ENGITYVSA 452
Query: 372 CHAGCSSWVVQDALDNSQVFYTNCSCV-----VEGNPV-LAGSC--DSTCSHLVVPFLLL 423
C AGC + + + NC+CV GN + G C D+ C + + FL++
Sbjct: 453 CLAGCQT----SNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVI 508
Query: 424 VSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCV 483
+ S L P ++L+LR +K + K+ A+GI + +R+LA +P+PV G IDT+C+
Sbjct: 509 SVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCL 568
Query: 484 HWALS-CGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQ 531
W CG R CR Y++++ R+ ++GL T S++ VL +L++
Sbjct: 569 KWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKK 617
>gi|225637477 solute carrier organic anion transporter family,
member 5A1 isoform 2 [Homo sapiens]
Length = 687
Score = 208 bits (529), Expect = 1e-53
Identities = 141/466 (30%), Positives = 214/466 (45%), Gaps = 67/466 (14%)
Query: 25 ASAPSNGNCSSYTET---------------QHLSVVGIMFVAQTLLGVGGVPIQPFGISY 69
ASAP++G C T H V + AQ L+G+G PI G +Y
Sbjct: 229 ASAPNDGLCQGGNSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTY 288
Query: 70 IDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWV 129
+DD NS LYL I++ + +GP + + LG L++ YVD P + L DPR++
Sbjct: 289 LDDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFI 344
Query: 130 GAWWLGFLIAAGAVALAAIPYFFFPKEMP-KEKRELQFRRKVLAVTDSPARKGKDSPSKQ 188
G WW GFL+ A A+ L P F FPK++P + K++ + + V AV+D K K + S+Q
Sbjct: 345 GNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQ 404
Query: 189 SPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMAT 248
+ + + G + ++ PR ++ L + FL V LS S++ T
Sbjct: 405 ADKKVSSMGFG-----------KDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFIT 453
Query: 249 FLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLL 308
F+PKF+E QF I AS A++ G + PS VGIV+GG ++K+L LG L ++ +
Sbjct: 454 FIPKFIESQFGIPASNASIYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGV 513
Query: 309 CLFFSLPLFFIGCSSHQIAGITHQTSAHPGL-----ELSPSCMEACSCPLDGFNPVCDPS 363
L LF +GC S + GI + P L L+ SC C C + + PVC S
Sbjct: 514 SLLCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCG-S 572
Query: 364 TRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVV------------------------ 399
+ Y PC AGC V L YT C+CV
Sbjct: 573 DGITYFNPCLAGC---VNSGNLSTGIRNYTECTCVQSRQVITPPTVGQRSQLRVVIVKTY 629
Query: 400 --EGNPVLAGSCDSTCSHLVVPFLLLVSLGSALACLTHTPSFMLIL 443
E ++G C TC+ L +PFL+ + + + + + ++ L
Sbjct: 630 LNENGYAVSGKCKRTCNTL-IPFLVFLFIVTFITACAQPSAIIVTL 674
>gi|93277099 solute carrier organic anion transporter family, member
6A1 [Homo sapiens]
Length = 719
Score = 176 bits (447), Expect = 4e-44
Identities = 128/515 (24%), Positives = 224/515 (43%), Gaps = 46/515 (8%)
Query: 33 CSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMM 92
C S + + + QT+ G+ G+P+ GI++ID+ ++ +YLGI +M+
Sbjct: 217 CQSSGISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVATHSAGIYLGIAECTSMI 276
Query: 93 GPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFF 152
G L + LG+ +++ V N ++ P W+ WW+ FL AA IP
Sbjct: 277 GYALGYVLGAPLVK--VPENTTSATNTTVNNGSPEWLWTWWINFLFAAVVAWCTLIPLSC 334
Query: 153 FPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAPNLTVIQF 212
FP MP R +RK L DS + +++ N
Sbjct: 335 FPNNMPGSTRIKARKRKQLHFFDSRLKD--------------------LKLGTN------ 368
Query: 213 IKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCL 272
IK L +++P+ + + LS+ + G + FLP +LE QF +T + A L G +
Sbjct: 369 IKDLCAALWILMKNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTVATTLAGLV 428
Query: 273 SFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGITHQ 332
P +G ++GGV+V L + ++ ++ L + + F+ C+ Q AGI
Sbjct: 429 LIPGGALGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQFAGINED 488
Query: 333 TSAHPGL-ELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVF 391
L L+ C E C C ++ +C +EY +PC AGC+ Q N +
Sbjct: 489 YDGTGKLGNLTAPCNEKCRCSSSIYSSICGRDD-IEYFSPCFAGCTYSKAQ----NQKKM 543
Query: 392 YTNCSCVVEG----------NPVLAGSCDSTCSHLVVPFLLLVSLGSALACLTHTPSFML 441
Y NCSC+ EG G CD+ C L + F+ + + + P +
Sbjct: 544 YYNCSCIKEGLITADAEGDFIDARPGKCDAKCYKLPL-FIAFIFSTLIFSGFSGVPIVLA 602
Query: 442 ILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWALS-CGRRAVCRYYNN 500
+ R V + ++LA+G+ ++ LRI +P P I + +T+C+ ++ CG C YN
Sbjct: 603 MTRVVPDKLRSLALGVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKCGHTGRCWIYNK 662
Query: 501 DLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKE 535
+ +G+ F K ++I + + +++ E
Sbjct: 663 TKMAFLLVGICFLCKLCTIIFTTIAFFIYKRRLNE 697
>gi|225637475 solute carrier organic anion transporter family,
member 5A1 isoform 3 [Homo sapiens]
Length = 793
Score = 135 bits (339), Expect = 1e-31
Identities = 89/307 (28%), Positives = 137/307 (44%), Gaps = 36/307 (11%)
Query: 270 GCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGI 329
G + PS VGIV+GG ++K+L LG L ++ + L LF +GC S + GI
Sbjct: 420 GVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGI 479
Query: 330 THQTSAHPGL-----ELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDA 384
+ P L L+ SC C C + + PVC S + Y PC AGC V
Sbjct: 480 NIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCG-SDGITYFNPCLAGC---VNSGN 535
Query: 385 LDNSQVFYTNCSCVV--------------------------EGNPVLAGSCDSTCSHLVV 418
L YT C+CV E ++G C TC+ L+
Sbjct: 536 LSTGIRNYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLI- 594
Query: 419 PFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAI 478
PFL+ + + + + + ++ LR V+ E++ A+G+QF+ LR LA++P+P+ G+ I
Sbjct: 595 PFLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVI 654
Query: 479 DTTCVHWALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEART 538
DTTC+ W CG + C YN R + GL K I L ++ ++ +
Sbjct: 655 DTTCMLWQQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEDGLQR 714
Query: 539 KESRSSP 545
+ R P
Sbjct: 715 RRQREFP 721
Score = 110 bits (276), Expect = 3e-24
Identities = 63/181 (34%), Positives = 94/181 (51%), Gaps = 20/181 (11%)
Query: 25 ASAPSNGNCSSYTET---------------QHLSVVGIMFVAQTLLGVGGVPIQPFGISY 69
ASAP++G C T H V + AQ L+G+G PI G +Y
Sbjct: 229 ASAPNDGLCQGGNSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTY 288
Query: 70 IDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWV 129
+DD NS LYL I++ + +GP + + LG L++ YVD P + L DPR++
Sbjct: 289 LDDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFI 344
Query: 130 GAWWLGFLIAAGAVALAAIPYFFFPKEM-PKEKRELQFRRKVLAVTDSPARKGKDSPSKQ 188
G WW GFL+ A A+ L P F FPK++ P+ K++ + + V AV+D K K + S+Q
Sbjct: 345 GNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQ 404
Query: 189 S 189
+
Sbjct: 405 A 405
>gi|186928854 mitochondrial ribosomal protein S31 [Homo sapiens]
Length = 395
Score = 32.7 bits (73), Expect = 0.91
Identities = 33/114 (28%), Positives = 49/114 (42%), Gaps = 9/114 (7%)
Query: 460 MFLRILAWMP------SPVIHGSAIDTTCVHWALSCGRRAVCRYYNNDLLRNRFIGLQFF 513
MF R+ ++P P+ GS +T+ L R RY ++ LL +Q +
Sbjct: 1 MFPRVSTFLPLRPLSRHPLSSGSP-ETSAAAIMLLTVRHGTVRYRSSALLARTKNNIQRY 59
Query: 514 FKTGSVICFALVLAVLRQQDKEARTKESRSSPA--VEQQLLVSGPGKKPEDSRV 565
F T SVIC +R ++ T ES+ S ++ LL G K E S V
Sbjct: 60 FGTNSVICSKKDKQSVRTEETSKETSESQDSEKENTKKDLLGIIKGMKVELSTV 113
>gi|160420317 filamin A, alpha isoform 2 [Homo sapiens]
Length = 2647
Score = 31.2 bits (69), Expect = 2.6
Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 4/59 (6%)
Query: 72 DFAHNSNSPLYLGILFA----VTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDP 126
D H SPL + + VT GPGL G+ + V+ EGG+SL I+ P
Sbjct: 1847 DNMHIPGSPLQFYVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGP 1905
>gi|116063573 filamin A, alpha isoform 1 [Homo sapiens]
Length = 2639
Score = 31.2 bits (69), Expect = 2.6
Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 4/59 (6%)
Query: 72 DFAHNSNSPLYLGILFA----VTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDP 126
D H SPL + + VT GPGL G+ + V+ EGG+SL I+ P
Sbjct: 1839 DNMHIPGSPLQFYVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGP 1897
>gi|148727298 keratin associated protein 10-6 [Homo sapiens]
Length = 365
Score = 30.8 bits (68), Expect = 3.5
Identities = 29/94 (30%), Positives = 36/94 (38%), Gaps = 9/94 (9%)
Query: 320 GCSSHQIAGITHQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSW 379
GC+S Q+S P S C +AC P+ PVC T E + C C
Sbjct: 199 GCTSSCTPSCCQQSSCQPTCCTSSPCQQACCVPVCCV-PVCCVPTCSEDSSSC---CQQS 254
Query: 380 VVQDALDNSQVFYTNCSCVVEGNPVLAGSCDSTC 413
Q A S C CV PV +G+ S C
Sbjct: 255 SCQPACCTSSPCQHAC-CV----PVCSGASTSCC 283
Score = 30.4 bits (67), Expect = 4.5
Identities = 24/94 (25%), Positives = 30/94 (31%)
Query: 320 GCSSHQIAGITHQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSW 379
GC+S Q+S S C +AC P+ C P V + C
Sbjct: 80 GCTSSCTPSCCQQSSCQLACCASSPCQQACCVPVCCKTVCCKPVCCVSVCCGDSSCCQQS 139
Query: 380 VVQDALDNSQVFYTNCSCVVEGNPVLAGSCDSTC 413
Q A S C V PV +G S C
Sbjct: 140 SCQSACCTSSPCQQACCVPVCCKPVCSGISSSCC 173
>gi|4504093 G protein-coupled receptor 32 [Homo sapiens]
Length = 356
Score = 30.4 bits (67), Expect = 4.5
Identities = 14/50 (28%), Positives = 28/50 (56%)
Query: 209 VIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQF 258
V+ + ++ RV+L+ + HP LL++ + L + + + FL F+ R F
Sbjct: 274 VVLLVHLWRRVMLKEIYHPRMLLILQASFALGCVNSSLNPFLYVFVGRDF 323
>gi|26051246 tumor necrosis factor ligand superfamily, member 13
isoform beta proprotein [Homo sapiens]
Length = 234
Score = 30.0 bits (66), Expect = 5.9
Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 11/83 (13%)
Query: 115 PEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQ-FRRKV--L 171
P G + +++P A WL + A GAVA A + ++ ELQ RR+V L
Sbjct: 14 PPGNMGGPVREPALSVALWLSWGAALGAVACA--------MALLTQQTELQSLRREVSRL 65
Query: 172 AVTDSPARKGKDSPSKQSPGEST 194
T P++ G+ P + P +S+
Sbjct: 66 QGTGGPSQNGEGYPWQSLPEQSS 88
>gi|4507599 tumor necrosis factor ligand superfamily, member 13
isoform alpha proprotein [Homo sapiens]
Length = 250
Score = 30.0 bits (66), Expect = 5.9
Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 11/83 (13%)
Query: 115 PEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQ-FRRKV--L 171
P G + +++P A WL + A GAVA A + ++ ELQ RR+V L
Sbjct: 14 PPGNMGGPVREPALSVALWLSWGAALGAVACA--------MALLTQQTELQSLRREVSRL 65
Query: 172 AVTDSPARKGKDSPSKQSPGEST 194
T P++ G+ P + P +S+
Sbjct: 66 QGTGGPSQNGEGYPWQSLPEQSS 88
>gi|26051248 tumor necrosis factor ligand superfamily, member 13
isoform gamma proprotein [Homo sapiens]
Length = 247
Score = 30.0 bits (66), Expect = 5.9
Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 11/83 (13%)
Query: 115 PEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQ-FRRKV--L 171
P G + +++P A WL + A GAVA A + ++ ELQ RR+V L
Sbjct: 14 PPGNMGGPVREPALSVALWLSWGAALGAVACA--------MALLTQQTELQSLRREVSRL 65
Query: 172 AVTDSPARKGKDSPSKQSPGEST 194
T P++ G+ P + P +S+
Sbjct: 66 QGTGGPSQNGEGYPWQSLPEQSS 88
>gi|31083174 interleukin 21 receptor precursor [Homo sapiens]
Length = 538
Score = 30.0 bits (66), Expect = 5.9
Identities = 23/81 (28%), Positives = 32/81 (39%), Gaps = 10/81 (12%)
Query: 339 LELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCV 398
L+ C CSC DG+ P D +E S ++D L ++ +C CV
Sbjct: 382 LDAEGPCTWPCSCEDDGY-PALDLDAGLE---------PSPGLEDPLLDAGTTVLSCGCV 431
Query: 399 VEGNPVLAGSCDSTCSHLVVP 419
G+P L G S L P
Sbjct: 432 SAGSPGLGGPLGSLLDRLKPP 452
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.139 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,783,635
Number of Sequences: 37866
Number of extensions: 1056309
Number of successful extensions: 3695
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 3546
Number of HSP's gapped (non-prelim): 74
length of query: 565
length of database: 18,247,518
effective HSP length: 108
effective length of query: 457
effective length of database: 14,157,990
effective search space: 6470201430
effective search space used: 6470201430
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.