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Search of human proteins with 223468602
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223468602 t-complex 10-like 2 [Homo sapiens]
(353 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223468602 t-complex 10-like 2 [Homo sapiens] 709 0.0
gi|105553088 t-complex 10 [Homo sapiens] 629 0.0
gi|21389535 T-complex 10A-2 [Homo sapiens] 333 2e-91
gi|130980075 centromere protein J [Homo sapiens] 58 1e-08
gi|171906567 peripheral benzodiazepine receptor-associated prote... 47 3e-05
gi|171906559 peripheral benzodiazepine receptor-associated prote... 47 3e-05
gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo... 42 8e-04
gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo... 42 8e-04
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa... 42 0.001
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 42 0.001
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 42 0.001
gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa... 41 0.001
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 41 0.002
gi|157738619 smoothelin-like 1 [Homo sapiens] 40 0.002
gi|254028234 MAP/microtubule affinity-regulating kinase 2 isofor... 40 0.003
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora... 40 0.003
gi|62955044 F-box protein 42 [Homo sapiens] 40 0.003
gi|254028237 MAP/microtubule affinity-regulating kinase 2 isofor... 40 0.004
gi|219842214 protein phosphatase 1, regulatory (inhibitor) subun... 40 0.004
gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun... 40 0.004
gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit... 40 0.004
gi|29893555 angiopoietin-like 6 [Homo sapiens] 40 0.004
gi|23308697 signal recognition particle receptor [Homo sapiens] 39 0.005
gi|116812616 RecQ protein-like 4 [Homo sapiens] 39 0.009
gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapi... 39 0.009
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 39 0.009
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 39 0.009
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 39 0.009
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 38 0.012
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 38 0.012
>gi|223468602 t-complex 10-like 2 [Homo sapiens]
Length = 353
Score = 709 bits (1829), Expect = 0.0
Identities = 353/353 (100%), Positives = 353/353 (100%)
Query: 1 MLEGQLEAREPKEGTHPEDPCPGAGAAMEKTPAAAEVPREDSNAGEMPSLQQQITSLHQE 60
MLEGQLEAREPKEGTHPEDPCPGAGAAMEKTPAAAEVPREDSNAGEMPSLQQQITSLHQE
Sbjct: 1 MLEGQLEAREPKEGTHPEDPCPGAGAAMEKTPAAAEVPREDSNAGEMPSLQQQITSLHQE 60
Query: 61 LGRQQSLWADIHRKLQSHMDALRKQNRELREELRGLQRQQWEAGKKPAASPHAGRESHTL 120
LGRQQSLWADIHRKLQSHMDALRKQNRELREELRGLQRQQWEAGKKPAASPHAGRESHTL
Sbjct: 61 LGRQQSLWADIHRKLQSHMDALRKQNRELREELRGLQRQQWEAGKKPAASPHAGRESHTL 120
Query: 121 ALEPAFGKISPLSADEETTPKYAGRKSQSATLLGQRWSSNHLAPPKPMSLKTERINSGKT 180
ALEPAFGKISPLSADEETTPKYAGRKSQSATLLGQRWSSNHLAPPKPMSLKTERINSGKT
Sbjct: 121 ALEPAFGKISPLSADEETTPKYAGRKSQSATLLGQRWSSNHLAPPKPMSLKTERINSGKT 180
Query: 181 PPQEDREKSPPGRRQDRSPAPTGRPTPGAERREVSEDGKIMHPSSRSLQNSGGRKSPVQA 240
PPQEDREKSPPGRRQDRSPAPTGRPTPGAERREVSEDGKIMHPSSRSLQNSGGRKSPVQA
Sbjct: 181 PPQEDREKSPPGRRQDRSPAPTGRPTPGAERREVSEDGKIMHPSSRSLQNSGGRKSPVQA 240
Query: 241 SQAATLQEQTAAAGVADRSSSVLGSSEGGFLSRVQAEEFASSSPDSAERQNLPVNPPSSL 300
SQAATLQEQTAAAGVADRSSSVLGSSEGGFLSRVQAEEFASSSPDSAERQNLPVNPPSSL
Sbjct: 241 SQAATLQEQTAAAGVADRSSSVLGSSEGGFLSRVQAEEFASSSPDSAERQNLPVNPPSSL 300
Query: 301 EIAQAMDTKMKKEEVQEEKRHPNGKADDCRRSGFPSEFPGALHAAPSRQDMGP 353
EIAQAMDTKMKKEEVQEEKRHPNGKADDCRRSGFPSEFPGALHAAPSRQDMGP
Sbjct: 301 EIAQAMDTKMKKEEVQEEKRHPNGKADDCRRSGFPSEFPGALHAAPSRQDMGP 353
>gi|105553088 t-complex 10 [Homo sapiens]
Length = 326
Score = 629 bits (1623), Expect = 0.0
Identities = 316/326 (96%), Positives = 319/326 (97%)
Query: 28 MEKTPAAAEVPREDSNAGEMPSLQQQITSLHQELGRQQSLWADIHRKLQSHMDALRKQNR 87
MEKTPAAAEVPREDSNAGEMPSLQQQITSLHQELGRQQSLWADIHRKLQSHMDALRKQNR
Sbjct: 1 MEKTPAAAEVPREDSNAGEMPSLQQQITSLHQELGRQQSLWADIHRKLQSHMDALRKQNR 60
Query: 88 ELREELRGLQRQQWEAGKKPAASPHAGRESHTLALEPAFGKISPLSADEETTPKYAGRKS 147
ELREELRGLQRQQWEAGKKPAASPHAGRESHTLALEPAFGKIS LSADE+TTPKYAGRKS
Sbjct: 61 ELREELRGLQRQQWEAGKKPAASPHAGRESHTLALEPAFGKISHLSADEDTTPKYAGRKS 120
Query: 148 QSATLLGQRWSSNHLAPPKPMSLKTERINSGKTPPQEDREKSPPGRRQDRSPAPTGRPTP 207
QSATLLGQRWSSNHLAPPKPMSLKTERINSGKTPPQEDREKSPPGRRQDRSPAPTGRPTP
Sbjct: 121 QSATLLGQRWSSNHLAPPKPMSLKTERINSGKTPPQEDREKSPPGRRQDRSPAPTGRPTP 180
Query: 208 GAERREVSEDGKIMHPSSRSLQNSGGRKSPVQASQAATLQEQTAAAGVADRSSSVLGSSE 267
GAERR VSEDGKIMHPSSRS QNSGGRKSPVQASQA TLQEQTAAA ADRSSSVLGSSE
Sbjct: 181 GAERRGVSEDGKIMHPSSRSPQNSGGRKSPVQASQATTLQEQTAAARGADRSSSVLGSSE 240
Query: 268 GGFLSRVQAEEFASSSPDSAERQNLPVNPPSSLEIAQAMDTKMKKEEVQEEKRHPNGKAD 327
GGFLSRVQA+EFASS+PDSAERQNLPVNPPSSLEIAQAMDTKMKKEEVQEEKRHP GKAD
Sbjct: 241 GGFLSRVQADEFASSAPDSAERQNLPVNPPSSLEIAQAMDTKMKKEEVQEEKRHPKGKAD 300
Query: 328 DCRRSGFPSEFPGALHAAPSRQDMGP 353
DCRRSGFPSEFPGALHAAPSRQDMGP
Sbjct: 301 DCRRSGFPSEFPGALHAAPSRQDMGP 326
>gi|21389535 T-complex 10A-2 [Homo sapiens]
Length = 215
Score = 333 bits (853), Expect = 2e-91
Identities = 166/212 (78%), Positives = 182/212 (85%)
Query: 1 MLEGQLEAREPKEGTHPEDPCPGAGAAMEKTPAAAEVPREDSNAGEMPSLQQQITSLHQE 60
ML GQLEAR+PKEGTHPEDPCPGAGA MEKT AAEV ED N GEMP LQQQI LHQE
Sbjct: 1 MLAGQLEARDPKEGTHPEDPCPGAGAVMEKTAVAAEVLTEDCNTGEMPPLQQQIIRLHQE 60
Query: 61 LGRQQSLWADIHRKLQSHMDALRKQNRELREELRGLQRQQWEAGKKPAASPHAGRESHTL 120
LGRQ+SLWAD+H KL+SH+DALR+QN ELRE+LR LQ Q+W+A KK AASPHAG+ESHTL
Sbjct: 61 LGRQKSLWADVHGKLRSHIDALREQNMELREKLRALQLQRWKARKKSAASPHAGQESHTL 120
Query: 121 ALEPAFGKISPLSADEETTPKYAGRKSQSATLLGQRWSSNHLAPPKPMSLKTERINSGKT 180
ALEPAFGKISPLSADEET PKYAG K+QSATLLGQR SSN+ APPKPMSLK ERI+S KT
Sbjct: 121 ALEPAFGKISPLSADEETIPKYAGHKNQSATLLGQRSSSNNSAPPKPMSLKIERISSWKT 180
Query: 181 PPQEDREKSPPGRRQDRSPAPTGRPTPGAERR 212
PPQE+R+K+ RRQDR PTGRPTP AERR
Sbjct: 181 PPQENRDKNLSRRRQDRRATPTGRPTPCAERR 212
>gi|130980075 centromere protein J [Homo sapiens]
Length = 1338
Score = 58.2 bits (139), Expect = 1e-08
Identities = 49/201 (24%), Positives = 91/201 (45%), Gaps = 22/201 (10%)
Query: 29 EKTPAAAEVPREDSNAGEMPSLQQQITSLHQELGRQQSLWADIHRKLQSHMDALRKQNRE 88
EK AA + E+ +L+QQI L ++L R+++ W+ H +L+S + L ++N +
Sbjct: 978 EKYTTAARTFPDKKEREEIQTLKQQIADLREDLKRKETKWSSTHSRLRSQIQMLVRENTD 1037
Query: 89 LREELRGLQRQQWEAGKKPAASPHAGRESHTLALEPAFGKISPLSADEETTPKYAGRKSQ 148
LREE++ ++R + +A K+ A+E + ++ T+ ++ +
Sbjct: 1038 LREEIKVMERFRLDAWKRAE------------AIESSL-EVEKKDKLANTSVRFQNSQIS 1084
Query: 149 SATLLGQRWSSNHLAPPKPMSLKTERINSGKTPPQEDREKSPPGRRQDRSP-APTGRPTP 207
S T + +++ N+L PM R S PP++ R P P P P
Sbjct: 1085 SGTQV-EKYKKNYL----PMQGNPPR-RSKSAPPRDLGNLDKGQAASPREPLEPLNFPDP 1138
Query: 208 GAERREVSED--GKIMHPSSR 226
+ E +D G+I HP +
Sbjct: 1139 EYKEEEEDQDIQGEISHPDGK 1159
>gi|171906567 peripheral benzodiazepine receptor-associated protein
1 isoform b [Homo sapiens]
Length = 1797
Score = 46.6 bits (109), Expect = 3e-05
Identities = 76/323 (23%), Positives = 120/323 (37%), Gaps = 51/323 (15%)
Query: 41 DSNAGEMPSLQQQITSLHQELGRQQSLWADIHRKLQSHMDALRKQNRELREELRGLQRQQ 100
DS + LQ ++ SL Q L + + A ++L+ + R RE +EE+R LQ+ Q
Sbjct: 358 DSALRKSQGLQSKLESLEQVLKHMREV-AQRRQQLEVEHEQARLSLREKQEEVRRLQQAQ 416
Query: 101 WEAGKKPAASPHAGRESHTLALEPAFGKISPLSADEETTPKYAGRKSQSATLLGQRWSSN 160
EA ++ H A++ + + A + +++ +LL Q +
Sbjct: 417 AEAQRE-----------HEGAVQLLESTLDSMQARVRELEEQCRSQTEQFSLLAQELQAF 465
Query: 161 HLAPPKPMSLKTERINSGK-----------TPPQEDREKSP---------PGRRQDRSPA 200
L P P+ L T ++ G + PQ R P PGR +S
Sbjct: 466 RLHPG-PLDLLTSALDCGSLGDCPPPPCCCSIPQPCRGSGPKDLDLPPGSPGRCTPKSSE 524
Query: 201 PTGRPTPGAERREVSEDGKIMHPS-SRSLQNSGGRKSPVQASQAATLQEQTAAAGVADRS 259
P G RR + + + S S S+ NS + P A+ E+ A V+
Sbjct: 525 PAPATLTGVPRRTAKKAESLSNSSHSESIHNS-PKSCPTPEVDTASEVEELEADSVSLLP 583
Query: 260 SSVLGSSEGG----FLSRVQAEEFASSSPDSAERQNLPVNPPSSLEIAQAMDTKMKKEEV 315
++ GS G FL+R F P+ LP+ + I MD
Sbjct: 584 AAPEGSRGGARIQVFLARYSYNPF--EGPNENPEAELPLTAGEYIYIYGNMD-------- 633
Query: 316 QEEKRHPNGKADDCRRSGFPSEF 338
E G+ D RR PS F
Sbjct: 634 --EDGFFEGELMDGRRGLVPSNF 654
>gi|171906559 peripheral benzodiazepine receptor-associated protein
1 isoform a [Homo sapiens]
Length = 1857
Score = 46.6 bits (109), Expect = 3e-05
Identities = 76/323 (23%), Positives = 120/323 (37%), Gaps = 51/323 (15%)
Query: 41 DSNAGEMPSLQQQITSLHQELGRQQSLWADIHRKLQSHMDALRKQNRELREELRGLQRQQ 100
DS + LQ ++ SL Q L + + A ++L+ + R RE +EE+R LQ+ Q
Sbjct: 418 DSALRKSQGLQSKLESLEQVLKHMREV-AQRRQQLEVEHEQARLSLREKQEEVRRLQQAQ 476
Query: 101 WEAGKKPAASPHAGRESHTLALEPAFGKISPLSADEETTPKYAGRKSQSATLLGQRWSSN 160
EA ++ H A++ + + A + +++ +LL Q +
Sbjct: 477 AEAQRE-----------HEGAVQLLESTLDSMQARVRELEEQCRSQTEQFSLLAQELQAF 525
Query: 161 HLAPPKPMSLKTERINSGK-----------TPPQEDREKSP---------PGRRQDRSPA 200
L P P+ L T ++ G + PQ R P PGR +S
Sbjct: 526 RLHPG-PLDLLTSALDCGSLGDCPPPPCCCSIPQPCRGSGPKDLDLPPGSPGRCTPKSSE 584
Query: 201 PTGRPTPGAERREVSEDGKIMHPS-SRSLQNSGGRKSPVQASQAATLQEQTAAAGVADRS 259
P G RR + + + S S S+ NS + P A+ E+ A V+
Sbjct: 585 PAPATLTGVPRRTAKKAESLSNSSHSESIHNS-PKSCPTPEVDTASEVEELEADSVSLLP 643
Query: 260 SSVLGSSEGG----FLSRVQAEEFASSSPDSAERQNLPVNPPSSLEIAQAMDTKMKKEEV 315
++ GS G FL+R F P+ LP+ + I MD
Sbjct: 644 AAPEGSRGGARIQVFLARYSYNPF--EGPNENPEAELPLTAGEYIYIYGNMD-------- 693
Query: 316 QEEKRHPNGKADDCRRSGFPSEF 338
E G+ D RR PS F
Sbjct: 694 --EDGFFEGELMDGRRGLVPSNF 714
>gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo
sapiens]
Length = 870
Score = 42.0 bits (97), Expect = 8e-04
Identities = 55/242 (22%), Positives = 90/242 (37%), Gaps = 15/242 (6%)
Query: 105 KKPAASPHAGRESHTLALEPAFGKISPLSADEETTPKYAGRKSQSATLLGQRWSSNHLAP 164
++ A A E L+L P+ + P D T PK + + + R S P
Sbjct: 633 RREARPARARGEIGGLSLSPSPERRKPPPPDPATKPKVSWIHGKHSAAAAGRAPS----P 688
Query: 165 PKPMSLKTERINSGKTPPQEDR----EKSPPGRRQDRSPAPTGRPTPGAERREVSEDGKI 220
P P S + K P + E P R +D +P P G P S
Sbjct: 689 PPPGSEAAPSPSKRKRTPSDKSAHTVEHGSP-RTRDPTPRPPGLPEEATALAAPSPPRAR 747
Query: 221 MHPSSRSLQNSGGRKSPVQASQAATL-----QEQTAAAGVADRSSSVLGSSEGGFLSRVQ 275
+ R L G R+SP + ++AA++ + +T + G A+ + G E +
Sbjct: 748 ARAAPRPLGAHGRRRSPAKRAEAASMLAADVRGKTRSLGRAEVALGAQGPREKPAPPQKA 807
Query: 276 AEEFASSSPDSAERQNLPVNPPSSLEIAQAMDTKMKKEEVQEEKRHPNGK-ADDCRRSGF 334
+SP A P + A +T KK +Q+ R + + A + R+G
Sbjct: 808 KRSVPPASPARAPPATETPGPEKAATDLPAPETPRKKTPIQKPPRKKSREAAGELGRAGA 867
Query: 335 PS 336
P+
Sbjct: 868 PT 869
>gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo
sapiens]
Length = 865
Score = 42.0 bits (97), Expect = 8e-04
Identities = 55/242 (22%), Positives = 90/242 (37%), Gaps = 15/242 (6%)
Query: 105 KKPAASPHAGRESHTLALEPAFGKISPLSADEETTPKYAGRKSQSATLLGQRWSSNHLAP 164
++ A A E L+L P+ + P D T PK + + + R S P
Sbjct: 628 RREARPARARGEIGGLSLSPSPERRKPPPPDPATKPKVSWIHGKHSAAAAGRAPS----P 683
Query: 165 PKPMSLKTERINSGKTPPQEDR----EKSPPGRRQDRSPAPTGRPTPGAERREVSEDGKI 220
P P S + K P + E P R +D +P P G P S
Sbjct: 684 PPPGSEAAPSPSKRKRTPSDKSAHTVEHGSP-RTRDPTPRPPGLPEEATALAAPSPPRAR 742
Query: 221 MHPSSRSLQNSGGRKSPVQASQAATL-----QEQTAAAGVADRSSSVLGSSEGGFLSRVQ 275
+ R L G R+SP + ++AA++ + +T + G A+ + G E +
Sbjct: 743 ARAAPRPLGAHGRRRSPAKRAEAASMLAADVRGKTRSLGRAEVALGAQGPREKPAPPQKA 802
Query: 276 AEEFASSSPDSAERQNLPVNPPSSLEIAQAMDTKMKKEEVQEEKRHPNGK-ADDCRRSGF 334
+SP A P + A +T KK +Q+ R + + A + R+G
Sbjct: 803 KRSVPPASPARAPPATETPGPEKAATDLPAPETPRKKTPIQKPPRKKSREAAGELGRAGA 862
Query: 335 PS 336
P+
Sbjct: 863 PT 864
>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
sapiens]
Length = 1297
Score = 41.6 bits (96), Expect = 0.001
Identities = 78/328 (23%), Positives = 137/328 (41%), Gaps = 49/328 (14%)
Query: 51 QQQITSLHQELGRQQSLWADIHRKL---QSHMDALRKQNRELREELRGLQRQQ------- 100
Q+Q+ L Q+L +Q+L + RK Q + L++Q ++ R+ L LQ Q+
Sbjct: 455 QRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVE 514
Query: 101 ------WEAGKKPAASPHAGRE-SHTLALE---PAFGKISPLSADEETTPKYAGRKS--- 147
++ G P+ P +E H +A++ PA + S E+ T +G +
Sbjct: 515 KKPLYHYKEGMSPSEKPAWAKEIPHLVAVKSQGPAL--TASQSVHEQPTKGLSGFQEALN 572
Query: 148 -QSATLLGQRWSSNHLAPPKPMSLKTERIN-SGKTPPQEDREKSPPGRRQDRSPAPTGRP 205
S + R +S+ + P+ + E+ + S +ED P R SPA +
Sbjct: 573 VTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKN 632
Query: 206 TPG----AERREVSEDGKIMHPSSRS----LQNSGGRKSPVQASQAATLQEQTAAAGVAD 257
+PG R S+ + +P R L++ R S +S ++T Q ++ G
Sbjct: 633 SPGNGSALGPRLGSQPIRASNPDLRRTEPILESPLQRTSSGSSSSSSTPSSQPSSQG-GS 691
Query: 258 RSSSVLGSSEGGFLSRVQAEEFASSSPDSAERQNLPVNPPSSLEIAQ--------AMDTK 309
+ S GSSE +RV+A + SP + V P S +I + A+ +
Sbjct: 692 QPGSQAGSSE---RTRVRANSKSEGSP-VLPHEPAKVKPEESRDITRPSRPADLTALAKE 747
Query: 310 MKKEEVQEEKRHPNGKADDCRRSGFPSE 337
+++ ++E R P K D S SE
Sbjct: 748 LRELRIEETNR-PMKKVTDYSSSSEESE 774
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 41.6 bits (96), Expect = 0.001
Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 7/83 (8%)
Query: 46 EMPSLQQQITSLHQELGRQQSLWADIHRKLQ-----SHMDALRKQNRELREELRGLQRQQ 100
E LQ Q+ L +L +++ A H KLQ +H DA ++QN+EL+E+LR L++ Q
Sbjct: 1585 EAQRLQAQLNELQAQLSQKEQ--AAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQ 1642
Query: 101 WEAGKKPAASPHAGRESHTLALE 123
E + A + G E L+
Sbjct: 1643 KENKELRAEAERLGHELQQAGLK 1665
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 41.6 bits (96), Expect = 0.001
Identities = 63/232 (27%), Positives = 87/232 (37%), Gaps = 25/232 (10%)
Query: 121 ALEPAFGKISPLSADEETTPKYAGRKSQSATLLGQRWSSNHLAPPKPMSLKTERINSGKT 180
A E G+ SP D + SQS R +S P P S + +
Sbjct: 2389 AYERVSGRTSPPLLDRARSRTPPSAPSQS------RMTSERA--PSPSSRMGQAPSQSLL 2440
Query: 181 PPQEDREKSP-PGRRQDRSPAPTGRPTPGAERREVSEDGKIMHPSSRSLQNS-------G 232
PP +D+ +SP P D+S + TP A + +S SS N G
Sbjct: 2441 PPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPG 2500
Query: 233 GRKSPVQASQAATLQEQTAAAGVAD-----RSSSVLGSSEGGFLSRVQAEEFASSSPDSA 287
S V A+T +Q +A RSSS SS S + +SSS S+
Sbjct: 2501 VPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSS 2560
Query: 288 ---ERQNLPVNPPSSLEIAQAMDTKMKKEEVQEEKRHPNGKADDCRRSGFPS 336
E +LPV P +L+ + T KE V+E + A RRS S
Sbjct: 2561 SDSEGSSLPVQPEVALKRVPS-PTPAPKEAVREGRPPEPTPAKRKRRSSSSS 2611
Score = 39.7 bits (91), Expect = 0.004
Identities = 44/190 (23%), Positives = 76/190 (40%), Gaps = 10/190 (5%)
Query: 97 QRQQWEAGKKPAASPHAGRESHTLALEPAFGKISPLSADEETTPKYAGRKSQSATLLGQR 156
QR+ EA K+PA P + ++L E + + ++ K GR+S+S++ +R
Sbjct: 154 QRRAREA-KQPAPEPP---KPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRER 209
Query: 157 WSSNHLAPPKPMSLKTERINSGKTPPQEDREKSPPGRRQDRSPAPTGRPTPGAERREVSE 216
S+ + S +R + TP + + K +++ RS + T P R S
Sbjct: 210 KKSSKKKKHRSESESKKRKHRSPTPKSKRKSKD---KKRKRSRSTTPAPKSRRAHRSTSA 266
Query: 217 DGKIMHPSSRSLQNSGGRKSPVQASQAATLQEQTAAAGVADRSSSVLGSSEGGFLSRVQA 276
D +SRS S K+ A + + G D S G++ R +
Sbjct: 267 DSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTS---TQRPSS 323
Query: 277 EEFASSSPDS 286
E A+ P S
Sbjct: 324 PETATKQPSS 333
Score = 38.9 bits (89), Expect = 0.007
Identities = 59/271 (21%), Positives = 104/271 (38%), Gaps = 36/271 (13%)
Query: 39 REDSNAGEMPSLQQQITSLHQELGRQQSLWADIHRKLQSHMDALRKQNRELREELRG--L 96
R+ S + + S ++Q + + R++ + H + + ++ R +R R R
Sbjct: 1788 RDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPT 1847
Query: 97 QRQQWEAGKKPA--------ASPHAGRESHTLALEPAFGKISPLSADEETTPKYAGRKSQ 148
R++ + PA ASP R S + IS + T+P + R+S+
Sbjct: 1848 SRKRSRSRTSPAPWKRSRSRASPATHRRSRSRT-----PLISRRRSRSRTSP-VSRRRSR 1901
Query: 149 SATLLGQRWSSNHLAPPKPMSLKTERINSGKTPP---QEDREKSPPGRRQDRSPAPTGRP 205
S T + +R S + +P + R + +TPP + R ++P RR+ RS P
Sbjct: 1902 SRTSVTRRRSRSRASPV------SRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTP---- 1951
Query: 206 TPGAERREVSEDGKIMHPSSRSLQNSGGRKSPVQASQAATLQEQTAAAGVADRSSSVLGS 265
P RR S + SRS R SP+ ++ + R+S V
Sbjct: 1952 -PVTRRRSRSRTPPVTRRRSRS------RTSPITRRRSRSRTSPVTRRRSRSRTSPVTRR 2004
Query: 266 SEGGFLSRVQAEEFASSSPDSAERQNLPVNP 296
S V S +P + R++ P
Sbjct: 2005 RSRSRTSPVTRRRSRSRTPPAIRRRSRSRTP 2035
Score = 38.5 bits (88), Expect = 0.009
Identities = 74/322 (22%), Positives = 123/322 (38%), Gaps = 58/322 (18%)
Query: 23 GAGAAMEKTPAAAEVPREDSNAGEMPSLQQQI-TSLHQELGRQQSLWADIHRKLQSHMDA 81
G+ ++ P+A+ P+E S + P + + T L Q S D +L S +
Sbjct: 1540 GSSQELDVKPSAS--PQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRL-SPRRS 1596
Query: 82 LRKQNRELREELRGLQRQQWEAGKKP---AASPHA-GRESHTLALEPAFGKISPLSADEE 137
+ E++++ R R Q + P A +P A R S + + G S+ E
Sbjct: 1597 RSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTE 1656
Query: 138 TTPKYAGRKSQSATLLGQRWSSNHLAPPKPMSLKTERINSGKTPPQ-------------- 183
++P++ KS++A R S PK S R S ++ P+
Sbjct: 1657 SSPEHPP-KSRTA-----RRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSA 1710
Query: 184 ----EDREKSPPGRRQDRSPAPTGRPTPGAERREVSEDGKIMHPSSRSLQNSGGRKSP-- 237
E R ++PP R RSP+ + P P + R P +++ G SP
Sbjct: 1711 SSSPETRSRTPPRHR--RSPSVSS-PEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKP 1767
Query: 238 --VQASQAATLQEQTAAAGVADRSSSVLGSSE------------------GGFLSRVQAE 277
+Q S++ + +E+T DRS S +S G+ SR A
Sbjct: 1768 RGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPAR 1827
Query: 278 EFASSSPDSAERQNLPVNPPSS 299
+ SS S R+ PP+S
Sbjct: 1828 Q-ESSRTSSRRRRGRSRTPPTS 1848
Score = 36.2 bits (82), Expect = 0.046
Identities = 50/205 (24%), Positives = 79/205 (38%), Gaps = 25/205 (12%)
Query: 164 PPKPMSLKTERINS-GKTPPQEDREKSPPGRRQDRSPAPTGRPTPGAER---REVSEDGK 219
PPKP SL E +S TP Q+ ++K R+ S +P +++ R SE K
Sbjct: 167 PPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKK 226
Query: 220 IMH--PSSRSLQNSGGRK-----SPVQASQAATLQEQTAAAGVADRSSSVLGSSEGGFLS 272
H P+ +S + S +K S A ++ T+A + +S S +
Sbjct: 227 RKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKT 286
Query: 273 RVQAEEFASSSPDSAER--QNLPVNPP--SSLEIAQAMDTKMKKEEVQEEKRHPNGKADD 328
A S SP S R + P + P +S + + +T K+ E + + K
Sbjct: 287 HTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKS 346
Query: 329 CRRSGFPSEFPGALHAAPSRQDMGP 353
R PS +P R GP
Sbjct: 347 ATR---PS-------PSPERSSTGP 361
Score = 32.7 bits (73), Expect = 0.50
Identities = 42/195 (21%), Positives = 71/195 (36%), Gaps = 36/195 (18%)
Query: 106 KPAASPHAGRESHTLALEPAFGKISPLSADEETTPKYAGRKSQSATLLGQRWSSNHLAPP 165
+P AS A + S AL+PA + S S+ ++ + S S++ SS+
Sbjct: 2508 EPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSS 2567
Query: 166 KPMS--LKTERINSGKTPPQED-REKSPPGRRQDRSPAPTGRPTPGAERREVSEDGKIMH 222
P+ + +R+ S P+E RE PP PTP +R
Sbjct: 2568 LPVQPEVALKRVPSPTPAPKEAVREGRPP------------EPTPAKRKR---------- 2605
Query: 223 PSSRSLQNSGGRKSPVQASQAATLQEQTAAAGVADRSSSVLGSSEGGFLSRVQAEEFASS 282
R S +S +++ ++++ + SSS SS S + A
Sbjct: 2606 -----------RSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKP 2654
Query: 283 SPDSAERQNLPVNPP 297
P + + P PP
Sbjct: 2655 GPQALPKPASPKKPP 2669
Score = 31.6 bits (70), Expect = 1.1
Identities = 61/297 (20%), Positives = 104/297 (35%), Gaps = 33/297 (11%)
Query: 4 GQLEAREPKEGTHPEDPCPGA-GAAMEKTPAAAEVPREDSNAGEMPSLQQQITSLHQELG 62
G+ +R P P G + +TPA R + P+ + + S G
Sbjct: 645 GRSRSRTPARRGRSRSRTPARRGRSRSRTPAR----RSGRSRSRTPARRGRSRSRTPRRG 700
Query: 63 RQQSLWADIHRKLQSHMDALRKQNRELREELRGLQRQQWEAGKKPAASPHAGRESHTLAL 122
R +S + R+ +SH ++ RG E K S R + + +
Sbjct: 701 RSRS--RSLVRRGRSHSRTPQR---------RGRSGSSSERKNKSRTSQRRSRSNSSPEM 749
Query: 123 EPAFGKISPLSADEETTPKYAGRKSQSATLLGQRWSSNHLAPPKPMSLKTERINSGKTPP 182
+ + +IS + ++P+ K++S L + S + P + R SG + P
Sbjct: 750 KKS--RISSRRSRSLSSPR---SKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQP 804
Query: 183 QEDREKSPPGRRQDRSPAPTGRPTPGAERREVSEDGKIMHPSSRSLQNSGGRKSPVQASQ 242
+ + ++PP R + S P + + R+ S S + G SP Q
Sbjct: 805 KA-KSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQ 863
Query: 243 AATLQEQTAAAGVADRSSSVLGSSEGGFLSRVQAEEFAS-SSPDSAERQNLPVNPPS 298
+ T Q R S S + SR + S SSP + P PS
Sbjct: 864 SVTPQ----------RRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPS 910
Score = 30.8 bits (68), Expect = 1.9
Identities = 33/157 (21%), Positives = 57/157 (36%), Gaps = 33/157 (21%)
Query: 104 GKKPAASPHAGRESHTLALEPAFGKISPLSADEETTPKYAGRKSQSATLLGQRWSSNHLA 163
G+ P +P + + + + S S+ ++ + S S++ SS A
Sbjct: 2593 GRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPA 2652
Query: 164 PPKPMSLKTERINSGKTPPQEDREKSPPGRRQDRSP---------------------APT 202
P P +L P +K PPG R+ RSP P+
Sbjct: 2653 KPGPQAL----------PKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPS 2702
Query: 203 GRPTPGAERREVSEDG--KIMHPSSRSLQNSGGRKSP 237
+P+P ++ SE G + SRS + R++P
Sbjct: 2703 PQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETP 2739
Score = 29.6 bits (65), Expect = 4.3
Identities = 34/126 (26%), Positives = 49/126 (38%), Gaps = 10/126 (7%)
Query: 181 PPQEDREKSPPGRRQDRSPAPT-GRPTPGAERREVSEDGKIMHPSSRSLQNSGGRKSPVQ 239
PPQED SPP ++ SP P RP E V +D P RS S ++ Q
Sbjct: 1171 PPQEDATASPPRQKDKFSPFPVQDRP----ESSLVFKDTLRTPPRERSGAGS-SPETKEQ 1225
Query: 240 ASQAATLQEQTAAAGVADRSSSVLGSSEGGFLSRVQAEEFASSSPDSAERQNLPVNPPSS 299
S T + V ++S G LS + +E S+ + + P S
Sbjct: 1226 NSALPTSSQDEELMEVVEKSEEPAGQ----ILSHLSSELKEMSTSNFESSPEVEERPAVS 1281
Query: 300 LEIAQA 305
L + Q+
Sbjct: 1282 LTLDQS 1287
Score = 28.5 bits (62), Expect = 9.5
Identities = 65/297 (21%), Positives = 101/297 (34%), Gaps = 33/297 (11%)
Query: 17 PEDPCPGAGAAMEKTPAAA--EVPREDSNAGEMPSLQQQITSLHQEL-----------GR 63
P +P A +++P + ++P+ S+ PS Q S H G
Sbjct: 390 PVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGS 449
Query: 64 QQSLWADIHRKLQSHMDALRKQNRELREELR-GLQRQQWEAGKKPAASPHAGRESHTLAL 122
+ + + K +SH A R ++ R G R A + + S + H+ +
Sbjct: 450 HREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSR 509
Query: 123 EPAFGKISPLSADEETTPKYAGRKSQSATLLGQRWSSNHLAPPKPMSLKTERINSGKTPP 182
P + + SA + R+ +S + WS + + S R S
Sbjct: 510 SPQWRRSR--SAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRS----- 562
Query: 183 QEDREKSPPGRRQDRSPAPTGRP---TPGAERREVSEDGKIMHPSSRSLQNSGGRKSPVQ 239
R + GR + R+PA GR TP A RR S SR+ G +S
Sbjct: 563 -HSRSPATRGRSRSRTPARRGRSRSRTP-ARRRSRSRTPTRRRSRSRTPARRGRSRSRTP 620
Query: 240 A-------SQAATLQEQTAAAGVADRSSSVLGSSEGGFLSRVQAEEFASSSPDSAER 289
A S + A + RS S + G SR A S S A R
Sbjct: 621 ARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARR 677
>gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo
sapiens]
Length = 1305
Score = 41.2 bits (95), Expect = 0.001
Identities = 71/301 (23%), Positives = 126/301 (41%), Gaps = 40/301 (13%)
Query: 51 QQQITSLHQELGRQQSLWADIHRKL---QSHMDALRKQNRELREELRGLQRQQ------- 100
Q+Q+ L Q+L +Q+L + RK Q + L++Q ++ R+ L LQ Q+
Sbjct: 455 QRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVE 514
Query: 101 ------WEAGKKPAASPHAGRE-SHTLALE---PAFGKISPLSADEETTPKYAGRKS--- 147
++ G P+ P +E H +A++ PA + S E+ T +G +
Sbjct: 515 KKPLYHYKEGMSPSEKPAWAKEIPHLVAVKSQGPAL--TASQSVHEQPTKGLSGFQEALN 572
Query: 148 -QSATLLGQRWSSNHLAPPKPMSLKTERIN-SGKTPPQEDREKSPPGRRQDRSPAPTGRP 205
S + R +S+ + P+ + E+ + S +ED P R SPA +
Sbjct: 573 VTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKN 632
Query: 206 TPG----AERREVSEDGKIMHPSSRS----LQNSGGRKSPVQASQAATLQEQTAAAGVAD 257
+PG R S+ + +P R L++ R S +S ++T Q ++ G
Sbjct: 633 SPGNGSALGPRLGSQPIRASNPDLRRTEPILESPLQRTSSGSSSSSSTPSSQPSSQG-GS 691
Query: 258 RSSSVLGSSEGGFLSRVQAEEFASSSPDSAERQNLPVNPPSSLEIAQAMDTKMKKEEVQE 317
+ S GSSE +RV+A + SP + V P S +I + K+ + E
Sbjct: 692 QPGSQAGSSE---RTRVRANSKSEGSP-VLPHEPAKVKPEESRDITRPSRPASYKKAIDE 747
Query: 318 E 318
+
Sbjct: 748 D 748
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 40.8 bits (94), Expect = 0.002
Identities = 63/306 (20%), Positives = 106/306 (34%), Gaps = 51/306 (16%)
Query: 31 TPAAAE-----VPREDSNAGEMPSLQQQITSLHQELGRQQSLWADIHRKLQSHMDALRKQ 85
TP+ AE P +DS Q ++S+ Q +Q + H Q ++ +
Sbjct: 376 TPSTAEPSKFPFPTKDS---------QHVSSVTQNQ-KQYDTSSKTHSNSQQGTSSMLED 425
Query: 86 NRELREELRGLQRQQWEAGKKPAASPHAGRESHTLALEPAFGKISPLSADEETTPKYAGR 145
+ +L + Q E +A P A + EP S + E T+ +
Sbjct: 426 DLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLP----EPVASAHSSSAESESTSDSDSSS 481
Query: 146 KSQSATLLGQRWSSNHLAPPKP-----------MSLKTERINSGKTPPQEDREKSPPGRR 194
S+S + + L P P + +++ PP+ R PP R
Sbjct: 482 DSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRH 541
Query: 195 QDR---SPAPTGR-------PTPGAERREVSEDGKIMHPSSRSLQNSGGRKSPVQASQAA 244
+ S + T + P P + + + HP RS Q S ++ P Q
Sbjct: 542 PESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVG 601
Query: 245 TLQ--EQTAAAGVADRSSSVLGSSEGGFLSRVQAEEFASSSPD---------SAERQNLP 293
T Q + A+ A +S+ G E G L ++ + P +A + P
Sbjct: 602 TKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKP 661
Query: 294 VNPPSS 299
PPSS
Sbjct: 662 AVPPSS 667
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 40.4 bits (93), Expect = 0.002
Identities = 69/350 (19%), Positives = 123/350 (35%), Gaps = 34/350 (9%)
Query: 7 EAREPKEGTHPEDPCPGAGAAMEKTPAAAEVPREDSNAGEMPSLQQQITSLHQELGRQQS 66
E E KEG ED + AA + P E++ ++ + + E G+Q+
Sbjct: 17 EKMEQKEGKLSEDGTTVSPAADNPEMSGGGAPAEETKGTAGKAINEGPPT---ESGKQEK 73
Query: 67 LWAD--IHRKLQSHMDALRKQNRELREELRGLQRQQWEAGKKPAASPHAGRESHTLALEP 124
A+ + +LQ + L + E + E G + + E K+ +E T+ +
Sbjct: 74 APAEDGMSAELQGEANGLDEVKVESQREAGGKEDAEAELKKEDGE-----KEETTVGSQE 128
Query: 125 AFGKISPLSADEETTPKYAGRKSQSATLLGQRWSSNHLAPPKPMSLKTERINSGKTPPQE 184
G+ EET + + + +TL ++ + K + SG+
Sbjct: 129 MTGR------KEETKSEPKEAEEKESTLASEKQKAEE---------KEAKPESGQKADAN 173
Query: 185 DREKSPPGRRQDRSPAPTGRPTPGAERREVSEDGKIMHPSSRSLQNSGGRKSPVQASQAA 244
DR+K P + A T +R+E S + K + S +K+ V+ A
Sbjct: 174 DRDKPEPKATVEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAES--QKAVVEDEAKA 231
Query: 245 TLQEQTAAAGVADRSSSVLGSSEGGFLSRVQAEEFASSSPDSAERQNLPVNPPSSLEIAQ 304
+E + + E AEE SP + Q++ P +
Sbjct: 232 EPKEPDGKEEAKHGAKEEADAKE----EAEDAEEAEPGSPSEEQEQDVEKEPEGGAGVIP 287
Query: 305 AMDTKMKKEEVQE-EKRHPNGKADDCRRSGFPSEFPGALHAAPSRQDMGP 353
+ + + E +G DC SG S P A ++PS P
Sbjct: 288 SSPEEWPESPTGEGHNLSTDGLGPDCVASGQTS--PSASESSPSDVPQSP 335
>gi|254028234 MAP/microtubule affinity-regulating kinase 2 isoform d
[Homo sapiens]
Length = 788
Score = 40.0 bits (92), Expect = 0.003
Identities = 60/250 (24%), Positives = 100/250 (40%), Gaps = 30/250 (12%)
Query: 116 ESHTLALEPAFGKISPLSADEETTPKYAGRKSQSATLLGQRWSSNHLAPPKPMS----LK 171
E T+ L+P + L+ +P + ++S SA +R+S P P S K
Sbjct: 369 EGDTITLKPR--PSADLTNSSAPSPSHKVQRSVSANPKQRRFSDQAAGPAIPTSNSYSKK 426
Query: 172 TERINSGKTPPQEDREKSPPGRRQDRSPAPTGRPTPGAERREVSEDGKIMHPSSRSLQNS 231
T+ N+ P+EDRE GR+ + P PG ER++ + PS+ S+ ++
Sbjct: 427 TQSNNAENKRPEEDRES---GRKASSTAKVPASPLPGLERKKTTPT-----PSTNSVLST 478
Query: 232 G---GRKSPV----QASQAATLQEQTAAAGVADRSSSVLGSSEGGFLSRVQAEEFASSSP 284
R SP+ QA+ + + R+S+ S+ Q ++ S+S
Sbjct: 479 STNRSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAAVSAARPRQHQKSMSASV 538
Query: 285 DSAERQNLPVNPPSSLEIAQAMDTKMKKEEVQEEKRH---PNGKADDCRRSGFPS--EFP 339
+ LP S+ E+ + T ++ V H +G A D R+ FP
Sbjct: 539 HPNKASGLPPT-ESNCEVPRP-STAPQRVPVASPSAHNISSSGGAPD--RTNFPRGVSSR 594
Query: 340 GALHAAPSRQ 349
HA RQ
Sbjct: 595 STFHAGQLRQ 604
>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 1 [Homo sapiens]
Length = 559
Score = 40.0 bits (92), Expect = 0.003
Identities = 63/302 (20%), Positives = 107/302 (35%), Gaps = 30/302 (9%)
Query: 59 QELGRQQSLWADIHRKLQSHMDALRKQNRELREELRGLQRQQWEAGKKPAASPHAGRESH 118
++ ++ S + H+ + H + RK + E + + L+R+Q ++ K + GR
Sbjct: 182 KDANKESSKTSKPHKVTKEHRERPRKDS-ESKSSSKELEREQAKSSKDTSRKLGEGR--- 237
Query: 119 TLALEPAFGKISPLSADEETTPKYAGRKSQSATLLGQRWSSNHLAPPKPMSLKTERINSG 178
L +E+ P A K L + S P S
Sbjct: 238 -------------LPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASS 284
Query: 179 KTPPQEDREKSPPGRRQDRSPAPTGRPTPGAERREVSEDGKIMHPSSRSLQNSGGRK--- 235
K P D K P ++Q +S + R PG R S ++ ++ G K
Sbjct: 285 KRPATADSPK-PSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKA 343
Query: 236 --SPVQASQAATLQEQTAAAGVADRSSSVLGSSEGGFLSRVQAEEFASSSPDSAERQNLP 293
P +A +A ++E + + +S S S S + +SS D QN
Sbjct: 344 ESEPREAKKALEVEESNSEDEASFKSESAQSSP-----SNSSSSSDSSSDSDFEPSQNHS 398
Query: 294 VNP-PSSLEIAQAMDTKMKKEEVQEEKRHPNGKADDCRRSGFPSEFPGALHAA-PSRQDM 351
P S +E Q+ ++ EE D R S SE + ++ PSR+
Sbjct: 399 QGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADSSLPSREPP 458
Query: 352 GP 353
P
Sbjct: 459 PP 460
>gi|62955044 F-box protein 42 [Homo sapiens]
Length = 717
Score = 40.0 bits (92), Expect = 0.003
Identities = 58/267 (21%), Positives = 97/267 (36%), Gaps = 33/267 (12%)
Query: 81 ALRKQNRELREE--LRGLQRQQWEAGKKPAASPHAGRE----SHTLALEPAFGKISPLSA 134
AL + RE R + +R + G+ P A R+ S +L PA G SP+
Sbjct: 381 ALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSREGSLSPARGDGSPILN 440
Query: 135 DEETTPKYAGRKSQSATLLGQRWSSNHLAPPKPMSLK---TERINSGKTPPQEDREKSPP 191
+P A S Q S + + P+ LK + G P Q+D
Sbjct: 441 GGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSI 500
Query: 192 GRRQDRSPAPTGRPTPGAERREVSEDGKIMHPSSRS---------------LQNSGGRKS 236
D PA + P G + R V G + HP ++ + G +
Sbjct: 501 DLNWDLKPASSSNPMDGMDNRTVG--GSMRHPPEQTNGVHTPPHVASALAGAVSPGALRR 558
Query: 237 PVQASQAATLQEQTAAAGVADRSSSVLGSSEGGFLSRVQAEEFASSSPDSAERQNLPV-- 294
++A +A + + +A+A ++ S GS LS + P + +LP
Sbjct: 559 SLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPPIA 618
Query: 295 -----NPPSSLEIAQAMDTKMKKEEVQ 316
+PP SL + + + M + +Q
Sbjct: 619 RRLGHHPPQSLNVGKPLYQSMNCKPMQ 645
>gi|254028237 MAP/microtubule affinity-regulating kinase 2 isoform e
[Homo sapiens]
Length = 719
Score = 39.7 bits (91), Expect = 0.004
Identities = 56/203 (27%), Positives = 82/203 (40%), Gaps = 26/203 (12%)
Query: 116 ESHTLALEPAFGKISPLSADEETTPKYAGRKSQSATLLGQRWSSNHLAPPKPMS----LK 171
E T+ L+P + L+ +P + ++S SA +R+S P P S K
Sbjct: 369 EGDTITLKPR--PSADLTNSSAPSPSHKVQRSVSANPKQRRFSDQAAGPAIPTSNSYSKK 426
Query: 172 TERINSGKTPPQEDREKSPPGRRQDRSPAPTGRPTPGAERREVS---EDGKIMHPSSRSL 228
T+ N+ P+EDRE GR+ + P PG ER++ + ++ S+
Sbjct: 427 TQSNNAENKRPEEDRES---GRKASSTAKVPASPLPGLERKKTTPTPSTNSVLSTSTNRS 483
Query: 229 QNSG--GRKSPVQASQAATLQEQTAAAGVADRSSSVLG-SSEGGFLSRVQAEEFASSSP- 284
+NS R S QAS ++ TA V S S SS GG R SS
Sbjct: 484 RNSPLLERASLGQAS-IQNGKDSTAPQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRST 542
Query: 285 -------DSAERQNLP--VNPPS 298
++QNLP V P S
Sbjct: 543 FHAGQLRQVRDQQNLPYGVTPAS 565
>gi|219842214 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform b [Homo sapiens]
Length = 943
Score = 39.7 bits (91), Expect = 0.004
Identities = 47/245 (19%), Positives = 88/245 (35%), Gaps = 16/245 (6%)
Query: 31 TPAAAEVPREDSNAGEMPSLQQQITSLHQELGRQQSLWADIHRKLQSHMDALRKQNRELR 90
TP E A + Q + ++ L Q I R + + +E
Sbjct: 584 TPVRDEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGRSRSTRTREQENEEKEKE 643
Query: 91 EELRGLQRQQWEAGKKPAASPHAGRESHTLALEPAFGKISPLSADEETTPKYAGRKSQSA 150
E+ + + +Q E + + ++ ++ + + + P+S TTP S +
Sbjct: 644 EKEKQDKEKQEEKKESETSREDEYKQKYSRTYDETYQRYRPVSTSSSTTP-----SSSLS 698
Query: 151 TLLGQRWSSNHLAPPKPMSLKTERINSGKTPPQ----EDREKSPPGRRQDRSPAPTGRPT 206
T+ ++S+ L P + T + G T E RE+ G + + + R
Sbjct: 699 TMSSSLYASSQLNRPNSLVGITSAYSRGITKENEREGEKREEEKEGEDKSQPKSIRERRR 758
Query: 207 PGAERREV-----SEDGKIMHPSSRSLQNSGGRKSPVQASQAATLQEQTAAAGVADRSSS 261
P +RR ++D +S G K Q + + + +AG DR S
Sbjct: 759 PREKRRSTGVSFWTQDSDENEQEQQSDTEEGSNKKETQTDSISRYETSSTSAG--DRYDS 816
Query: 262 VLGSS 266
+LG S
Sbjct: 817 LLGRS 821
>gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 39.7 bits (91), Expect = 0.004
Identities = 47/245 (19%), Positives = 88/245 (35%), Gaps = 16/245 (6%)
Query: 31 TPAAAEVPREDSNAGEMPSLQQQITSLHQELGRQQSLWADIHRKLQSHMDALRKQNRELR 90
TP E A + Q + ++ L Q I R + + +E
Sbjct: 671 TPVRDEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGRSRSTRTREQENEEKEKE 730
Query: 91 EELRGLQRQQWEAGKKPAASPHAGRESHTLALEPAFGKISPLSADEETTPKYAGRKSQSA 150
E+ + + +Q E + + ++ ++ + + + P+S TTP S +
Sbjct: 731 EKEKQDKEKQEEKKESETSREDEYKQKYSRTYDETYQRYRPVSTSSSTTP-----SSSLS 785
Query: 151 TLLGQRWSSNHLAPPKPMSLKTERINSGKTPPQ----EDREKSPPGRRQDRSPAPTGRPT 206
T+ ++S+ L P + T + G T E RE+ G + + + R
Sbjct: 786 TMSSSLYASSQLNRPNSLVGITSAYSRGITKENEREGEKREEEKEGEDKSQPKSIRERRR 845
Query: 207 PGAERREV-----SEDGKIMHPSSRSLQNSGGRKSPVQASQAATLQEQTAAAGVADRSSS 261
P +RR ++D +S G K Q + + + +AG DR S
Sbjct: 846 PREKRRSTGVSFWTQDSDENEQEQQSDTEEGSNKKETQTDSISRYETSSTSAG--DRYDS 903
Query: 262 VLGSS 266
+LG S
Sbjct: 904 LLGRS 908
>gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 39.7 bits (91), Expect = 0.004
Identities = 47/245 (19%), Positives = 88/245 (35%), Gaps = 16/245 (6%)
Query: 31 TPAAAEVPREDSNAGEMPSLQQQITSLHQELGRQQSLWADIHRKLQSHMDALRKQNRELR 90
TP E A + Q + ++ L Q I R + + +E
Sbjct: 671 TPVRDEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGRSRSTRTREQENEEKEKE 730
Query: 91 EELRGLQRQQWEAGKKPAASPHAGRESHTLALEPAFGKISPLSADEETTPKYAGRKSQSA 150
E+ + + +Q E + + ++ ++ + + + P+S TTP S +
Sbjct: 731 EKEKQDKEKQEEKKESETSREDEYKQKYSRTYDETYQRYRPVSTSSSTTP-----SSSLS 785
Query: 151 TLLGQRWSSNHLAPPKPMSLKTERINSGKTPPQ----EDREKSPPGRRQDRSPAPTGRPT 206
T+ ++S+ L P + T + G T E RE+ G + + + R
Sbjct: 786 TMSSSLYASSQLNRPNSLVGITSAYSRGITKENEREGEKREEEKEGEDKSQPKSIRERRR 845
Query: 207 PGAERREV-----SEDGKIMHPSSRSLQNSGGRKSPVQASQAATLQEQTAAAGVADRSSS 261
P +RR ++D +S G K Q + + + +AG DR S
Sbjct: 846 PREKRRSTGVSFWTQDSDENEQEQQSDTEEGSNKKETQTDSISRYETSSTSAG--DRYDS 903
Query: 262 VLGSS 266
+LG S
Sbjct: 904 LLGRS 908
>gi|29893555 angiopoietin-like 6 [Homo sapiens]
Length = 470
Score = 39.7 bits (91), Expect = 0.004
Identities = 35/102 (34%), Positives = 49/102 (48%), Gaps = 9/102 (8%)
Query: 25 GAAMEKTPAAAEVPREDSNAGEMPSLQQQITSLHQELGRQQSLWADIHRKLQSHMDALRK 84
GA PA+ E +NA E+ +L+ ++ H+EL R+ A + + ALRK
Sbjct: 40 GAVCWSGPASTRATPEAANASELAALRMRV-GRHEELLRELQRLAAADGAVAGEVRALRK 98
Query: 85 QNRELREELRGLQRQ-QWEAGKKPAASPHAGRESHTLALEPA 125
++R L L L+ Q Q EAG P A P A L EPA
Sbjct: 99 ESRGLSARLGQLRAQLQHEAG--PGAGPGA-----DLGAEPA 133
>gi|23308697 signal recognition particle receptor [Homo sapiens]
Length = 638
Score = 39.3 bits (90), Expect = 0.005
Identities = 30/127 (23%), Positives = 57/127 (44%), Gaps = 10/127 (7%)
Query: 212 REVSEDGKIMHPSS-RSLQNSGGRKSPVQASQAATLQEQTAAAGVADRSSSVLGSSEGGF 270
RE E KI P++ + ++S K PV++ ++ A + + + S+G
Sbjct: 122 REAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSDG-- 179
Query: 271 LSRVQAEEFASSSPDSAERQNLPVNPPSSLEIAQAMDTKMKKEEVQEEKRHPNGKADDCR 330
A+S P AE+ LPV P + +E+++ + K+EE ++ K++
Sbjct: 180 -------PLATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKST 232
Query: 331 RSGFPSE 337
+S P E
Sbjct: 233 KSDAPKE 239
>gi|116812616 RecQ protein-like 4 [Homo sapiens]
Length = 1208
Score = 38.5 bits (88), Expect = 0.009
Identities = 71/310 (22%), Positives = 114/310 (36%), Gaps = 62/310 (20%)
Query: 73 RKLQSHMDALRKQNRELREELRGLQRQQWEAG---KKPAASPHAGRES--------HTLA 121
R Q ++A ++ R L E R L+R +AG + + P A E+ H
Sbjct: 25 RPSQDDVEAAPEETRALYREYRTLKRTTGQAGGGLRSSESLPAAAEEAPEPRCWGPHLNR 84
Query: 122 LEPAFGKISPLSADEETTPKYAGRKS-------QSATLLGQR-W----SSNHLAPPKPMS 169
+ +P + + + P Y R Q+ LG+R W +S+ + PKP
Sbjct: 85 AATKSPQSTPGRSRQGSVPDYGQRLKANLKGTLQAGPALGRRPWPLGRASSKASTPKPPG 144
Query: 170 LK-----TERINSGKTPPQEDREKSPPGRRQD--------------------RSPAPTGR 204
E+++ PPQ + PGR Q S P
Sbjct: 145 TGPVPSFAEKVSD--EPPQLPEPQPRPGRLQHLQASLSQRLGSLDPGWLQRCHSEVPDFL 202
Query: 205 PTPGAERREV-SEDGKIMHPSSRSLQNSGGRKSPVQASQAATLQEQTAAAGVADRSSSVL 263
P A R ++ SE+ +++ P ++ G Q +A+ QE V+ R S
Sbjct: 203 GAPKACRPDLGSEESQLLIPGESAVLGPGAGS---QGPEASAFQE------VSIRVGSPQ 253
Query: 264 GSSEGGFLSRVQAEEFASSSPDSAERQNLPVNPPSSLEIAQAMDTKMKKEEVQEEKRHPN 323
SS GG R E + SP ++++ PPS A A++ E VQ + P
Sbjct: 254 PSSSGGEKRRWNEEPW--ESPAQVQQESSQAGPPSEGAGAVAVEEDPPGEPVQAQPPQPC 311
Query: 324 GKADDCRRSG 333
+ R G
Sbjct: 312 SSPSNPRYHG 321
>gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapiens]
Length = 1790
Score = 38.5 bits (88), Expect = 0.009
Identities = 52/257 (20%), Positives = 95/257 (36%), Gaps = 22/257 (8%)
Query: 5 QLEAREPKEGTHPEDPCPGAGAAMEKTPAAAEVPREDSNAGEMPSLQQQITSLHQELGRQ 64
++E REP E +EK PAA A P + +++ L + G
Sbjct: 1516 KVEIREPSEEEE-------VVVTIEKPPAAEPTYTTWKRARIFPMIFKKVRGLADKRGIV 1568
Query: 65 QSLWADIHRKLQSHMDALRKQNRELREELRGLQRQQWEAGKKPAA-SPHAGRESHTLALE 123
+ R+L+ K + E + E+ S S + E
Sbjct: 1569 DLEGEEWQRRLEEEDKDYLKLTLDQEEATESTVESEEESSSDYTEYSEEESEFSESETTE 1628
Query: 124 PAFGKISPLSADEETTPKYAGRKSQSATLLGQRWSSNH-LAPPKPMSLKTERINSGKTPP 182
+P +E +TP+ +S+S G++ N LA +PM + + + K P
Sbjct: 1629 EESESETPSEEEESSTPE--SEESESTESEGEKARKNIVLARRRPMVEEVKEVKGRKEEP 1686
Query: 183 QEDREKSPPGRRQDRSPAPTGRPTP-----GAERREVSEDGKIMHPSSRSLQNSGGRKSP 237
QE+ +K P ++ S P P E +++ E+G S+ S GG +S
Sbjct: 1687 QEE-QKEPKMEEEEHSEEEESGPAPVEESTDPEAQDIPEEG-----SAESASVEGGVESE 1740
Query: 238 VQASQAATLQEQTAAAG 254
++ ++ + +G
Sbjct: 1741 EESESGSSSSSSESQSG 1757
>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
[Homo sapiens]
Length = 2191
Score = 38.5 bits (88), Expect = 0.009
Identities = 38/117 (32%), Positives = 49/117 (41%), Gaps = 11/117 (9%)
Query: 192 GRRQDRSPAPTGR-PTPGAERREVSEDGKIMHPSSRSLQNSGGRKSPVQASQAATLQE-- 248
G Q P GR P+ G + R + M PSS + GG P T+
Sbjct: 828 GPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGG---PGMGPPMPTVNRKA 884
Query: 249 QTAAAGVADRSSSVLGSSEGGFLSRVQAEEFASSSPDSAERQNLPVNPPSSLEIAQA 305
Q AAA V +++ S +G F Q+ ASSSP S P+N SSL QA
Sbjct: 885 QEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQ-----PMNNSSSLMNTQA 936
>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
[Homo sapiens]
Length = 2231
Score = 38.5 bits (88), Expect = 0.009
Identities = 38/117 (32%), Positives = 49/117 (41%), Gaps = 11/117 (9%)
Query: 192 GRRQDRSPAPTGR-PTPGAERREVSEDGKIMHPSSRSLQNSGGRKSPVQASQAATLQE-- 248
G Q P GR P+ G + R + M PSS + GG P T+
Sbjct: 815 GPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGG---PGMGPPMPTVNRKA 871
Query: 249 QTAAAGVADRSSSVLGSSEGGFLSRVQAEEFASSSPDSAERQNLPVNPPSSLEIAQA 305
Q AAA V +++ S +G F Q+ ASSSP S P+N SSL QA
Sbjct: 872 QEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQ-----PMNNSSSLMNTQA 923
>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
[Homo sapiens]
Length = 2178
Score = 38.5 bits (88), Expect = 0.009
Identities = 38/117 (32%), Positives = 49/117 (41%), Gaps = 11/117 (9%)
Query: 192 GRRQDRSPAPTGR-PTPGAERREVSEDGKIMHPSSRSLQNSGGRKSPVQASQAATLQE-- 248
G Q P GR P+ G + R + M PSS + GG P T+
Sbjct: 815 GPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGG---PGMGPPMPTVNRKA 871
Query: 249 QTAAAGVADRSSSVLGSSEGGFLSRVQAEEFASSSPDSAERQNLPVNPPSSLEIAQA 305
Q AAA V +++ S +G F Q+ ASSSP S P+N SSL QA
Sbjct: 872 QEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQ-----PMNNSSSLMNTQA 923
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 38.1 bits (87), Expect = 0.012
Identities = 38/166 (22%), Positives = 77/166 (46%), Gaps = 10/166 (6%)
Query: 36 EVPREDSNAGEMPSLQQQITSLHQELGRQQSLWADIHRKLQSHMDALRKQNRELREELRG 95
E+ + ++AG+ ++ + L + + + LW ++ S + + QNRE + L+G
Sbjct: 1653 ELKAQMASAGQ--GKEEAVKQLRKMQAQMKELWREVEETRTSR-EEIFSQNRESEKRLKG 1709
Query: 96 LQRQQWEAGKKPAASPHAGRESH----TLALEPAFGKISPLSADEETTPKYAGRKSQSAT 151
L+ + ++ AAS A R++ +A E A G +S + EE + GR Q
Sbjct: 1710 LEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKR-QLEGRLGQLEE 1768
Query: 152 LLGQRWSSNHLAPP--KPMSLKTERINSGKTPPQEDREKSPPGRRQ 195
L + S++ L + + L+ E + + + + K+ GR+Q
Sbjct: 1769 ELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQ 1814
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 38.1 bits (87), Expect = 0.012
Identities = 38/166 (22%), Positives = 77/166 (46%), Gaps = 10/166 (6%)
Query: 36 EVPREDSNAGEMPSLQQQITSLHQELGRQQSLWADIHRKLQSHMDALRKQNRELREELRG 95
E+ + ++AG+ ++ + L + + + LW ++ S + + QNRE + L+G
Sbjct: 1645 ELKAQMASAGQ--GKEEAVKQLRKMQAQMKELWREVEETRTSR-EEIFSQNRESEKRLKG 1701
Query: 96 LQRQQWEAGKKPAASPHAGRESH----TLALEPAFGKISPLSADEETTPKYAGRKSQSAT 151
L+ + ++ AAS A R++ +A E A G +S + EE + GR Q
Sbjct: 1702 LEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKR-QLEGRLGQLEE 1760
Query: 152 LLGQRWSSNHLAPP--KPMSLKTERINSGKTPPQEDREKSPPGRRQ 195
L + S++ L + + L+ E + + + + K+ GR+Q
Sbjct: 1761 ELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQ 1806
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.124 0.351
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,736,162
Number of Sequences: 37866
Number of extensions: 925184
Number of successful extensions: 6385
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 555
Number of HSP's that attempted gapping in prelim test: 5571
Number of HSP's gapped (non-prelim): 1295
length of query: 353
length of database: 18,247,518
effective HSP length: 103
effective length of query: 250
effective length of database: 14,347,320
effective search space: 3586830000
effective search space used: 3586830000
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.