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Search of human proteins with 223005857
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223005857 WD repeat domain 67 isoform 2 [Homo sapiens]
(970 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223005857 WD repeat domain 67 isoform 2 [Homo sapiens] 1951 0.0
gi|223005859 WD repeat domain 67 isoform 1 [Homo sapiens] 1769 0.0
gi|148746195 trichohyalin [Homo sapiens] 65 3e-10
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 60 8e-09
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 60 1e-08
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 59 3e-08
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 59 3e-08
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 58 5e-08
gi|32189425 WD repeat domain 69 [Homo sapiens] 58 5e-08
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 57 6e-08
gi|4557741 platelet-activating factor acetylhydrolase, isoform I... 57 1e-07
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 57 1e-07
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 57 1e-07
gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens] 57 1e-07
gi|219803769 trichoplein [Homo sapiens] 56 1e-07
gi|14150056 trichoplein [Homo sapiens] 56 1e-07
gi|4505257 moesin [Homo sapiens] 55 2e-07
gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens] 55 2e-07
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 55 4e-07
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 55 4e-07
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 55 4e-07
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 55 4e-07
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 54 5e-07
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 54 5e-07
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 54 7e-07
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 54 7e-07
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 54 7e-07
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 54 7e-07
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 54 7e-07
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 54 7e-07
>gi|223005857 WD repeat domain 67 isoform 2 [Homo sapiens]
Length = 970
Score = 1951 bits (5053), Expect = 0.0
Identities = 970/970 (100%), Positives = 970/970 (100%)
Query: 1 MQSTDLGNKESGKIWHRKPSPATRDGIIVNIIHNTSDYHPKVLRFLNVAFDGTGDCLIAG 60
MQSTDLGNKESGKIWHRKPSPATRDGIIVNIIHNTSDYHPKVLRFLNVAFDGTGDCLIAG
Sbjct: 1 MQSTDLGNKESGKIWHRKPSPATRDGIIVNIIHNTSDYHPKVLRFLNVAFDGTGDCLIAG 60
Query: 61 DHQGNIYVFDLHGNRFNLVQRTAQACTALAFNLRRKSEFLVALADYSIKCFDTVTKELVS 120
DHQGNIYVFDLHGNRFNLVQRTAQACTALAFNLRRKSEFLVALADYSIKCFDTVTKELVS
Sbjct: 61 DHQGNIYVFDLHGNRFNLVQRTAQACTALAFNLRRKSEFLVALADYSIKCFDTVTKELVS 120
Query: 121 WMRGHESSVFSISVHASGKYAITTSSDTAQLWDLDTFQRKRKLNIRQSVGIQKVFFLPLS 180
WMRGHESSVFSISVHASGKYAITTSSDTAQLWDLDTFQRKRKLNIRQSVGIQKVFFLPLS
Sbjct: 121 WMRGHESSVFSISVHASGKYAITTSSDTAQLWDLDTFQRKRKLNIRQSVGIQKVFFLPLS 180
Query: 181 NTILSCFKDNSIFAWECDTLFCKYQLPAPPESSSILYKVFAVTRDGRILAAGGKSNHLHL 240
NTILSCFKDNSIFAWECDTLFCKYQLPAPPESSSILYKVFAVTRDGRILAAGGKSNHLHL
Sbjct: 181 NTILSCFKDNSIFAWECDTLFCKYQLPAPPESSSILYKVFAVTRDGRILAAGGKSNHLHL 240
Query: 241 WCLEARQLFRIIQMPTKVRAIRHLEFLPDSFDAGSNQVLGVLSQDGIMRFINMQTCKLLF 300
WCLEARQLFRIIQMPTKVRAIRHLEFLPDSFDAGSNQVLGVLSQDGIMRFINMQTCKLLF
Sbjct: 241 WCLEARQLFRIIQMPTKVRAIRHLEFLPDSFDAGSNQVLGVLSQDGIMRFINMQTCKLLF 300
Query: 301 EIGSLDEGISSSAISPHGRYIASIMENGSLNIYSVQALTQEINKPPPPLVKVIEDLPKNK 360
EIGSLDEGISSSAISPHGRYIASIMENGSLNIYSVQALTQEINKPPPPLVKVIEDLPKNK
Sbjct: 301 EIGSLDEGISSSAISPHGRYIASIMENGSLNIYSVQALTQEINKPPPPLVKVIEDLPKNK 360
Query: 361 LSSSDLKMKVTSGRVQQPAKSRESKMQTRILKQDLTGDFESKKNELPDGLNKKRLQILLK 420
LSSSDLKMKVTSGRVQQPAKSRESKMQTRILKQDLTGDFESKKNELPDGLNKKRLQILLK
Sbjct: 361 LSSSDLKMKVTSGRVQQPAKSRESKMQTRILKQDLTGDFESKKNELPDGLNKKRLQILLK 420
Query: 421 GYGEYPTKYRMFIWRSLLQLPENHTAFSTLIDKGTHVAFLNLQKKYPIKSRKLLRVLQRT 480
GYGEYPTKYRMFIWRSLLQLPENHTAFSTLIDKGTHVAFLNLQKKYPIKSRKLLRVLQRT
Sbjct: 421 GYGEYPTKYRMFIWRSLLQLPENHTAFSTLIDKGTHVAFLNLQKKYPIKSRKLLRVLQRT 480
Query: 481 LSALAHWSVIFSDTPYLPLLAFPFVKLFQNNQLICFEVIATLIINWCQHWFEYFPNPPIN 540
LSALAHWSVIFSDTPYLPLLAFPFVKLFQNNQLICFEVIATLIINWCQHWFEYFPNPPIN
Sbjct: 481 LSALAHWSVIFSDTPYLPLLAFPFVKLFQNNQLICFEVIATLIINWCQHWFEYFPNPPIN 540
Query: 541 ILSMIENVLAFHDKELLQHFIDHDITSQLYAWPLLETVFSEVLTREEWLKLFDNIFSNHP 600
ILSMIENVLAFHDKELLQHFIDHDITSQLYAWPLLETVFSEVLTREEWLKLFDNIFSNHP
Sbjct: 541 ILSMIENVLAFHDKELLQHFIDHDITSQLYAWPLLETVFSEVLTREEWLKLFDNIFSNHP 600
Query: 601 SFLLMTVVAYNICSRTPLLSCNLKDDFEFFFHHRNNLDINVVIRQVYHLMETTPTDIHPD 660
SFLLMTVVAYNICSRTPLLSCNLKDDFEFFFHHRNNLDINVVIRQVYHLMETTPTDIHPD
Sbjct: 601 SFLLMTVVAYNICSRTPLLSCNLKDDFEFFFHHRNNLDINVVIRQVYHLMETTPTDIHPD 660
Query: 661 SMLNVFVALTKGQYPVFNQYPKFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQR 720
SMLNVFVALTKGQYPVFNQYPKFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQR
Sbjct: 661 SMLNVFVALTKGQYPVFNQYPKFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQR 720
Query: 721 VEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRF 780
VEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRF
Sbjct: 721 VEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRF 780
Query: 781 LKLQQDQQEMELRRLDDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAG 840
LKLQQDQQEMELRRLDDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAG
Sbjct: 781 LKLQQDQQEMELRRLDDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAG 840
Query: 841 ETQSQKTQKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRF 900
ETQSQKTQKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRF
Sbjct: 841 ETQSQKTQKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRF 900
Query: 901 QNEQDSSCLPRTSQLNDSSEMDPSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARH 960
QNEQDSSCLPRTSQLNDSSEMDPSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARH
Sbjct: 901 QNEQDSSCLPRTSQLNDSSEMDPSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARH 960
Query: 961 RCQTPHLLAA 970
RCQTPHLLAA
Sbjct: 961 RCQTPHLLAA 970
>gi|223005859 WD repeat domain 67 isoform 1 [Homo sapiens]
Length = 1066
Score = 1769 bits (4583), Expect = 0.0
Identities = 923/1068 (86%), Positives = 935/1068 (87%), Gaps = 100/1068 (9%)
Query: 1 MQSTDLGNKESGKIWHRKPSPATRDGIIVNIIHNTSDYHPKVLRFLNVAFDGTGDCLIAG 60
MQSTDLGNKESGKIWHRKPSPATRDGIIVNIIHNTSDYHPKVLRFLNVAFDGTGDCLIAG
Sbjct: 1 MQSTDLGNKESGKIWHRKPSPATRDGIIVNIIHNTSDYHPKVLRFLNVAFDGTGDCLIAG 60
Query: 61 DHQGNIYVFDLHGNRFNLVQRTAQACTALAFNLRRKSEFLVALADYSIKCFDTVTKELVS 120
DHQGNIYVFDLHGNRFNLVQRTAQACTALAFNLRRKSEFLVALADYSIKCFDTVTKELVS
Sbjct: 61 DHQGNIYVFDLHGNRFNLVQRTAQACTALAFNLRRKSEFLVALADYSIKCFDTVTKELVS 120
Query: 121 WMRGHESSVFSISVHASGKYAITTSSDTAQLWDLDTFQRKRKLNIRQSVGIQKVFFLPLS 180
WMRGHESSVFSISVHASGKYAITTSSDTAQLWDLDTFQRKRKLNIRQSVGIQKVFFLPLS
Sbjct: 121 WMRGHESSVFSISVHASGKYAITTSSDTAQLWDLDTFQRKRKLNIRQSVGIQKVFFLPLS 180
Query: 181 NTILSCFKDNSIFAWECDTLFCKYQLPAPPESSSILYKVFAVTRDGRILAAGGKSNHLHL 240
NTILSCFKDNSIFAWECDTLFCKYQLPAPPESSSILYKVFAVTRDGRILAAGGKSNHLHL
Sbjct: 181 NTILSCFKDNSIFAWECDTLFCKYQLPAPPESSSILYKVFAVTRDGRILAAGGKSNHLHL 240
Query: 241 WCLEARQLFRIIQMPTKVRAIRHLEFLPDSFDAGSNQVLGVLSQDGIMRFINMQTCKLLF 300
WCLEARQLFRIIQMPTKVRAIRHLEFLPDSFDAGSNQVLGVLSQDGIMRFINMQTCKLLF
Sbjct: 241 WCLEARQLFRIIQMPTKVRAIRHLEFLPDSFDAGSNQVLGVLSQDGIMRFINMQTCKLLF 300
Query: 301 EIGSLDEGISSSAISPHGRYIASIMENGSLNIYSVQALTQEINKPPPPLVKVIEDLPKNK 360
EIGSLDEGISSSAISPHGRYIASIMENGSLNIYSVQALTQEINKPPPPLVKVIEDLPKNK
Sbjct: 301 EIGSLDEGISSSAISPHGRYIASIMENGSLNIYSVQALTQEINKPPPPLVKVIEDLPKNK 360
Query: 361 LSSSDLKMKVTSGRVQQPAKSRESKMQTRILKQDLTGDFESKKNELPDGLNKKRLQILLK 420
LSSSDLKMKVTSGRVQQPAKSRESKMQTRILKQDLTGDFESKKNELPDGLNKKRLQILLK
Sbjct: 361 LSSSDLKMKVTSGRVQQPAKSRESKMQTRILKQDLTGDFESKKNELPDGLNKKRLQILLK 420
Query: 421 GYGEYPTKYRMFIWRSLLQLPENHTAFSTLIDKGTHVAFLNLQKKYPIKSRKLLRVLQRT 480
GYGEYPTKYRMFIWRSLLQLPENHTAFSTLIDKGTHVAFLNLQKKYPIKSRKLLRVLQRT
Sbjct: 421 GYGEYPTKYRMFIWRSLLQLPENHTAFSTLIDKGTHVAFLNLQKKYPIKSRKLLRVLQRT 480
Query: 481 LSALAHWSVIFSDTPYLPLLAFPFVKLFQNNQLICFEVIATLIINWCQHWFEYFPNPPIN 540
LSALAHWSVIFSDTPYLPLLAFPFVKLFQNNQLICFEVIATLIINWCQHWFEYFPNPPIN
Sbjct: 481 LSALAHWSVIFSDTPYLPLLAFPFVKLFQNNQLICFEVIATLIINWCQHWFEYFPNPPIN 540
Query: 541 ILSMIENVLAFHDKELLQHFIDHDITSQLYAWPLLETVFSEVLTREEWLKLFDNIFSNHP 600
ILSMIENVLAFHDKELLQHFIDHDITSQLYAWPLLETVFSEVLTREEWLKLFDNIFSNHP
Sbjct: 541 ILSMIENVLAFHDKELLQHFIDHDITSQLYAWPLLETVFSEVLTREEWLKLFDNIFSNHP 600
Query: 601 SFLLMTVVAYNICSRTPLLSCNLKDDFEFFFHHRNNLDINVVIRQVYHLMETTPTDIHPD 660
SFLLMTVVAYNICSRTPLLSCNLKDDFEFFFHHRNNLDINVVIRQVYHLMETTPTDIHPD
Sbjct: 601 SFLLMTVVAYNICSRTPLLSCNLKDDFEFFFHHRNNLDINVVIRQVYHLMETTPTDIHPD 660
Query: 661 SMLNVFVALTKGQYPVFNQYPKFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQR 720
SMLNVFVALTKGQYPVFNQYPKFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQR
Sbjct: 661 SMLNVFVALTKGQYPVFNQYPKFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQR 720
Query: 721 VEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRF 780
VEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRF
Sbjct: 721 VEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRF 780
Query: 781 LKLQQDQQEMELRRLDDEIGR-------------------------------KNLTENQE 809
LKLQQDQQEMELRRLDDEIGR KNLTENQE
Sbjct: 781 LKLQQDQQEMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQE 840
Query: 810 ALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQK-WKEAEGK--------EFRL 860
ALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQK KE K ++++
Sbjct: 841 ALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQI 900
Query: 861 RSAKK---------------ASALSDASRKWFLKQEINAAVEHAE---NPCHKEEPRFQN 902
+S K A L + RK + INA VE +E R ++
Sbjct: 901 QSLHKQKCDDLQRNKCYQEVAKLLRENRRKEI--EIINAMVEEEAKKWKEAEGKEFRLRS 958
Query: 903 EQDSSCL----------------------------PRTSQLNDS------------SEMD 922
+ +S L PR DS SEMD
Sbjct: 959 AKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSSEMD 1018
Query: 923 PSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHRCQTPHLLAA 970
PSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHRCQTPHLLAA
Sbjct: 1019 PSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHRCQTPHLLAA 1066
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 65.1 bits (157), Expect = 3e-10
Identities = 68/295 (23%), Positives = 130/295 (44%), Gaps = 44/295 (14%)
Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEE 749
Q+ R + + + L +R+ + ++ + +QR++ E ++ +LL++ EE R++ L +E+E
Sbjct: 536 QQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQE 595
Query: 750 KMIQQRQRLAAV-------KRELKVKEMHLQDAARRRFLKL--QQDQQEMELRRLDDEIG 800
+ ++QR + V +RE ++K ++ R++ LK Q+++++ +LRR E
Sbjct: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR 655
Query: 801 RKNL--TENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEF 858
+ L E +E L + ++ + + RR+ +L E + +A E + KW
Sbjct: 656 EQRLKREEEEERLEQRLKREHEEERREQELAE---EEQEQARERIKSRIPKW-------- 704
Query: 859 RLRSAKKASALSDASRKWFLKQEINAAVEHA-ENPCHKEEPRFQNEQDSSCLPRTSQL-- 915
+W L+ E +A P +E R + EQ+ R S+L
Sbjct: 705 ----------------QWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQW 748
Query: 916 NDSSEMDPSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHRCQTPHLLAA 970
+ Q RR W + +K RQRL+AR R Q L A
Sbjct: 749 QEEERAHRQQQEEEQRRDFTWQWQAE---EKSERGRQRLSARPPLREQRERQLRA 800
Score = 64.7 bits (156), Expect = 4e-10
Identities = 49/236 (20%), Positives = 111/236 (47%), Gaps = 21/236 (8%)
Query: 686 DYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLL 745
+ + + +++R ++ + RE+Q + + + +Q++ E ++++ LR+ ++ RRE L
Sbjct: 342 EQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQL 401
Query: 746 QEE-----------EKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQD-----QQE 789
+ E E+ +++ Q+L + E + ++ H Q+ +R + Q++ ++E
Sbjct: 402 RREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKRE 461
Query: 790 MELRRLDDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQK 849
E R + E ++ L +QE +E + R+ E E E + Q+ ++
Sbjct: 462 EETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKR 521
Query: 850 WKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQD 905
+E E + RLRS ++ + R+ LK+E +E + E R + EQ+
Sbjct: 522 QEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQ-----ERREQRLKREQE 572
Score = 62.4 bits (150), Expect = 2e-09
Identities = 61/252 (24%), Positives = 124/252 (49%), Gaps = 31/252 (12%)
Query: 688 QTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRR------ 741
Q ++++ ++ +E LRE + +Q + Q R E+E ++++LL + ETRR
Sbjct: 1019 QYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELER 1078
Query: 742 -----EMLLQEEEKMI---------QQRQRLAAVKRELKVKEMHL--QDAARRRFLKLQ- 784
E L QEEE+++ Q+R+R + EL+ +E L ++ +RR +L+
Sbjct: 1079 QYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELER 1138
Query: 785 QDQQEMELRRLDDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQS 844
Q ++E E+++ ++++ R+ E ++ +E+ YR + +L++ L E E +
Sbjct: 1139 QYREEEEVQQEEEQLLRE---EPEKRRRQELERQ---YREEEELQQEEEQLLREEQEKRR 1192
Query: 845 QKTQK-WKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCH-KEEPRFQN 902
Q+ ++ ++E E + + R + + KW + E AV + C +E +F+
Sbjct: 1193 QERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQ 1252
Query: 903 EQDSSCLPRTSQ 914
+DS R SQ
Sbjct: 1253 LEDSQLRDRQSQ 1264
Score = 60.5 bits (145), Expect = 8e-09
Identities = 68/297 (22%), Positives = 132/297 (44%), Gaps = 37/297 (12%)
Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQ-----RVEDEAWYQK----QELLRKAEETR 740
+E E+++ +E RE Q E+ K+++Q R E+E Q+ Q+L RK EE R
Sbjct: 255 KEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEER 314
Query: 741 REMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQ--EMELRRLDDE 798
RE QEE + Q+R+ +RE +++ Q+ R + L+ +Q+++ E +LRR +E
Sbjct: 315 REQ--QEERREQQERREQQEERREQQLRRE--QEERREQQLRREQEEERREQQLRREQEE 370
Query: 799 IGRKNLTENQEALAKEMRADADAYRRK---------VDLEEHMFHKLIEAGETQSQKTQK 849
R+ ++ L +E + + R+ + E+ + + E Q ++ Q+
Sbjct: 371 ERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQE 430
Query: 850 WKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQ---NEQDS 906
+ E K + R ++ + R W ++E E H++E R Q +Q+
Sbjct: 431 EERHEQKHEQERREQRLKREQEERRDWLKREE--------ETERHEQERRKQQLKRDQEE 482
Query: 907 SCLPRTSQLNDSSEMDPSTQISLNRRAVEWDTTGQNLIK--KVRNLRQRLTARARHR 961
R +L + + + R + + Q L + + L+QRL + + R
Sbjct: 483 ERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLR 539
Score = 59.3 bits (142), Expect = 2e-08
Identities = 71/276 (25%), Positives = 118/276 (42%), Gaps = 43/276 (15%)
Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWY-----QKQELLRKAEETRRE-- 742
QE ER RE++ + + + D + E+E +KQ+L R EE RRE
Sbjct: 429 QEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERW 488
Query: 743 MLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRK 802
+ L+EEE+ QQ +R ++RE Q+ R + LK Q++++ ++ R ++ R+
Sbjct: 489 LKLEEEERREQQERREQQLRRE--------QEERREQRLKRQEEEERLQQRLRSEQQLRR 540
Query: 803 NLTENQEALAK---EMRADADAYRRKVDLE-EHMFHKLIEAGETQSQKTQKWKEAEGKEF 858
E +E L K E R + + +++ E E +L++ E + Q+ K ++ E E
Sbjct: 541 EQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQ 600
Query: 859 RLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDS 918
RL+ + L+QE E E +EEP + Q QL S
Sbjct: 601 RLKREEVER----------LEQE-----ERREQRLKREEPEEERRQ---------QLLKS 636
Query: 919 SEMDPSTQISLNRRAVEWDTTGQNLIKKVRNLRQRL 954
E + Q L R E ++ L QRL
Sbjct: 637 EEQEERRQQQLRREQQERREQRLKREEEEERLEQRL 672
Score = 58.2 bits (139), Expect = 4e-08
Identities = 54/241 (22%), Positives = 112/241 (46%), Gaps = 15/241 (6%)
Query: 691 ERERIRNDELDYLRERQTVEDMQAKVDQQ-----RVEDEAWYQKQELLRKAEETRREMLL 745
+ E++R EL LR + E Q + ++Q E++ W +++ +LRK EE +E
Sbjct: 206 DEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP 265
Query: 746 QEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKNLT 805
Q + ++ ++ ++L ++R+ +E ++ ++R + QQ +++ E R + + R+
Sbjct: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQ 325
Query: 806 ENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFRLRSAKK 865
E +E +E R + R + + E + E E + Q+ ++ +E E +E +LR ++
Sbjct: 326 ERRE--QQEERREQQLRREQEERREQQLRREQEE-ERREQQLRREQEEERREQQLRREQQ 382
Query: 866 ASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSSEMDPST 925
R+ L++E E + E + + EQ L R QL E +
Sbjct: 383 LRREQQLRREQQLRREQQLRREQQ----LRREQQLRREQQ---LRREQQLRREQEEERHE 435
Query: 926 Q 926
Q
Sbjct: 436 Q 436
Score = 58.2 bits (139), Expect = 4e-08
Identities = 53/232 (22%), Positives = 112/232 (48%), Gaps = 17/232 (7%)
Query: 688 QTQERERIRNDE-LDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQ 746
+ Q+++R+R ++ L +E + E + + +QQ ++ ++++ LR+ +E RRE L+
Sbjct: 293 EEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLR 352
Query: 747 EEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQ---EMELRRLDDEIGRKN 803
E++ ++ Q+L + E + ++ ++ RR +L+++QQ E +LRR + ++ R+
Sbjct: 353 REQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRR-EQQLRREQ 411
Query: 804 LTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWK-EAEGKEFRLRS 862
++ L +E + RR+ + E H E Q ++ Q+ K E E + L+
Sbjct: 412 QLRREQQLRREQQ-----LRREQEEERH------EQKHEQERREQRLKREQEERRDWLKR 460
Query: 863 AKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQ 914
++ RK LK++ +EE R Q E+ L R +
Sbjct: 461 EEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQE 512
Score = 56.6 bits (135), Expect = 1e-07
Identities = 55/231 (23%), Positives = 103/231 (44%), Gaps = 25/231 (10%)
Query: 688 QTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLL-- 745
Q + R+ ++ +E + R Q Q K DQ+ E W + +E R+ ++ RRE L
Sbjct: 451 QEERRDWLKREE-ETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRR 509
Query: 746 ------------QEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELR 793
QEEE+ +QQR R R + +E Q R +L+Q+++E L+
Sbjct: 510 EQEERREQRLKRQEEEERLQQRLRSEQQLRR-EQEERREQLLKREEEKRLEQERREQRLK 568
Query: 794 RLDDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEA 853
R +E R++ +E ++ R + R LE+ + + +E E + ++ Q+ K
Sbjct: 569 REQEE--RRDQLLKREEERRQQRLKREQEER---LEQRLKREEVERLEQEERREQRLKRE 623
Query: 854 EGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQ 904
E +E R + K+ + ++ +++ E E +EE + EQ
Sbjct: 624 EPEEERRQQLLKSEEQEERRQQQLRREQ----QERREQRLKREEEEERLEQ 670
Score = 53.1 bits (126), Expect = 1e-06
Identities = 67/299 (22%), Positives = 127/299 (42%), Gaps = 39/299 (13%)
Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRVED-----EAWYQK------QELLRKAEE 738
+E E+ R E LR+RQ+ +D+Q + +Q+ D W Q+ +E L + E+
Sbjct: 1245 RENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQ 1304
Query: 739 ---TRREMLLQEEEKMI----QQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEME 791
RR+ QEE++++ ++++R R+ + +E LQ+ + + ++D++ E
Sbjct: 1305 KEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFRE 1364
Query: 792 LRRLDDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWK 851
E GRK L E Q +E RK EE + + + +K++
Sbjct: 1365 EELRHQEQGRKFLEEEQRLRRQER-------ERKFLKEEQQLRCQEREQQLRQDRDRKFR 1417
Query: 852 EAE------GKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQD 905
E E ++ + R ++ + RK FL++E E +EE + E++
Sbjct: 1418 EEEQQLSRQERDRKFREEEQQVRRQERERK-FLEEEQQLRQERHRK--FREEEQLLQERE 1474
Query: 906 SSCLPRTSQLNDSSEMDPSTQI---SLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHR 961
L R Q D ++ Q+ +R+ E + Q +K Q+L + R R
Sbjct: 1475 EQQLHR--QERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQR 1531
Score = 50.4 bits (119), Expect = 8e-06
Identities = 59/268 (22%), Positives = 107/268 (39%), Gaps = 36/268 (13%)
Query: 688 QTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELL----RKAEE----- 738
Q QERE +E +ER D +QR ++E W Q+QE R+AEE
Sbjct: 142 QEQERELAEGEEQSEKQERLEQRD------RQRRDEELWRQRQEWQEREERRAEEEQLQS 195
Query: 739 --------------TRREMLLQ-----EEEKMIQQRQRLAAVKRELKVKEMHLQDAARRR 779
RR LL+ EEK Q+R+R V +E + KE ++ R+
Sbjct: 196 CKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRK 255
Query: 780 FLKLQQDQQEMELRRLDDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEA 839
+ Q+++ R L +E + E QE + R + + ++++ E+ + K E
Sbjct: 256 EEEKLQEEEPQRQRELQEEEEQLRKLERQE--LRRERQEEEQQQQRLRREQQLRRKQEEE 313
Query: 840 GETQSQKTQKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPR 899
Q ++ ++ +E ++ R + + + +++ E +EE R
Sbjct: 314 RREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERR 373
Query: 900 FQNEQDSSCLPRTSQLNDSSEMDPSTQI 927
Q + L R QL ++ Q+
Sbjct: 374 EQQLRREQQLRREQQLRREQQLRREQQL 401
Score = 49.7 bits (117), Expect = 1e-05
Identities = 73/322 (22%), Positives = 133/322 (41%), Gaps = 52/322 (16%)
Query: 685 VDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRR--- 741
++ Q ++ E ++ +E LRE Q + Q R E+E ++++LLR+ E RR
Sbjct: 1076 LERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE 1135
Query: 742 --------EMLLQEEEKMI---------QQRQRLAAVKRELKVKEMHL--QDAARRRFLK 782
E + QEEE+++ Q+ +R + EL+ +E L ++ +RR +
Sbjct: 1136 LERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER 1195
Query: 783 LQQDQQEMEL------RRLDDEIGRKNL-----TENQEALA-----------KEMRADAD 820
+Q ++E EL +R DE R +L E + A+ ++ R D
Sbjct: 1196 ERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLED 1255
Query: 821 AYRRKVDLEEHMFHKLIEAGE-TQSQKTQKWKEAEGKEFRLRSAKKASALSDASRKWFLK 879
+ R ++ + H L E E + Q+ ++W++ + + F + +A R+
Sbjct: 1256 SQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRD-RHFPEEEQLEREEQKEAKRRDRKS 1314
Query: 880 QEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSSEMDPSTQISLNRRAVEWDTT 939
QE + +EE R + E D QL E P + +R+ E +
Sbjct: 1315 QEEKQLLRE-----EREEKRRRQETDRK-FREEEQLLQEREEQPLRRQERDRKFREEELR 1368
Query: 940 GQNLIKKVRNLRQRLTARARHR 961
Q +K QRL + R R
Sbjct: 1369 HQEQGRKFLEEEQRLRRQERER 1390
Score = 47.4 bits (111), Expect = 7e-05
Identities = 49/221 (22%), Positives = 96/221 (43%), Gaps = 32/221 (14%)
Query: 688 QTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRR----EM 743
Q +E E+++ +E LRE + Q + Q R + + ++++LL + E RR E
Sbjct: 929 QYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK 988
Query: 744 LLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKN 803
+EEE++ Q+ ++L +RE + ++ R++ K + QQE E + L +E ++
Sbjct: 989 KYREEEELQQEEEQLLREEREKRRRQEW-----ERQYRKKDELQQEEE-QLLREEREKRR 1042
Query: 804 LTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFRLRSA 863
L E + YR + +L++ L E ET+ ++ + R
Sbjct: 1043 LQERERQ-----------YREEEELQQEEEQLLGEERETRRRQELE-----------RQY 1080
Query: 864 KKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQ 904
+K L + ++ + E C +EE Q E+
Sbjct: 1081 RKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEE 1121
Score = 47.0 bits (110), Expect = 9e-05
Identities = 51/216 (23%), Positives = 98/216 (45%), Gaps = 20/216 (9%)
Query: 682 KFIVDYQT---QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEE 738
KF+ + Q QERER E LR ++ + ++ D++ E+E +QE RK E
Sbjct: 1375 KFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFRE 1434
Query: 739 TRREMLLQE-------EEKMIQQRQRLAAVKRELKVKEMHLQDAAR----RRFLKLQQDQ 787
+++ QE EE+ ++Q + + E ++E Q R R+FL+ +Q
Sbjct: 1435 EEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQL 1494
Query: 788 QEMELRRLDDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKT 847
+ E R E ++ ++ L +E + +RK EE + + + +
Sbjct: 1495 RRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRD 1554
Query: 848 QKWKEAEGKEFRLRSAKKASALS--DASRKWFLKQE 881
+K++E E +LR ++ LS + RK+ L+++
Sbjct: 1555 RKFREEE----QLRQEREEQQLSRQERDRKFRLEEQ 1586
Score = 46.2 bits (108), Expect = 1e-04
Identities = 52/232 (22%), Positives = 104/232 (44%), Gaps = 17/232 (7%)
Query: 682 KFIVDYQT---QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEE 738
KF+ + Q Q+R+R E LR ++ + + D++ E+E Q++E + + +
Sbjct: 1516 KFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQ 1575
Query: 739 TRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAAR----RRFLKLQQDQQEMELRR 794
R EE+K+ +Q Q ++ E +++ Q R R+F + +Q QE E ++
Sbjct: 1576 ERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQ 1635
Query: 795 LDDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAE 854
L + + E + L ++ R + R E +L++ GE Q + Q+
Sbjct: 1636 LHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREE--EQLLQEGEEQQLRRQE----- 1688
Query: 855 GKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEP-RFQNEQD 905
++ + R ++ + RK FL++E + E +EE R + EQ+
Sbjct: 1689 -RDRKFREEEQQLRRQERERK-FLQEEQQLRRQELERKFREEEQLRQETEQE 1738
Score = 45.1 bits (105), Expect = 3e-04
Identities = 48/214 (22%), Positives = 97/214 (45%), Gaps = 13/214 (6%)
Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEE 749
QER+R +E LR ++ + ++ D++ E+E Q+ E + + R +EE+
Sbjct: 1639 QERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQ 1698
Query: 750 KMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKNLTENQE 809
++ +Q + ++ E +++ L+ R +L+Q+ ++ +LRR E RK L E Q
Sbjct: 1699 QLRRQERERKFLQEEQQLRRQELERKFREE-EQLRQETEQEQLRR--QERYRKILEEEQ- 1754
Query: 810 ALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFRLRSAKKASAL 869
+ R + R++ D + +L + E Q ++Q+ +E +LR ++ L
Sbjct: 1755 --LRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQL 1812
Query: 870 ----SDASRKWFLKQEINAAVEHAENPCHKEEPR 899
D +W +E +E E +E R
Sbjct: 1813 RPQQRDGKYRW---EEEQLQLEEQEQRLRQERDR 1843
Score = 42.7 bits (99), Expect = 0.002
Identities = 58/228 (25%), Positives = 103/228 (45%), Gaps = 26/228 (11%)
Query: 688 QTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREML--L 745
Q++ R R E R+ Q + + + + Q E+E +++Q+ EE RR+
Sbjct: 716 QSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQ----EEEQRRDFTWQW 771
Query: 746 QEEEKMIQQRQRLAA--VKRELKVKEMHLQDAARR--RFLKLQQDQQEMELRRLDDEIGR 801
Q EEK + RQRL+A RE + +++ ++ +R RFL ++++++ +R + E
Sbjct: 772 QAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRERE-KE 830
Query: 802 KNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQ-KTQKWK---EAEGKE 857
E +E L + RA +++ EE + E +Q Q + QKW+ E E K
Sbjct: 831 LQFLEEEEQLQRRERA------QQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKR 884
Query: 858 FRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQD 905
R K + ++ L QE E E + E R + EQ+
Sbjct: 885 RRHTLYAKPALQEQLRKEQQLLQE-----EEEELQREEREKRRRQEQE 927
Score = 42.7 bits (99), Expect = 0.002
Identities = 56/237 (23%), Positives = 106/237 (44%), Gaps = 25/237 (10%)
Query: 688 QTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQEL--LRKAEETR--REM 743
+ + R+R +E LRE + + + + D++ E+E Q++E LR+ E R RE
Sbjct: 1306 EAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREE 1365
Query: 744 LLQEEE---KMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIG 800
L+ +E K +++ QRL +RE K + Q L+ Q+ +Q++ R
Sbjct: 1366 ELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQ-------LRCQEREQQLRQDR-----D 1413
Query: 801 RKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFRL 860
RK E Q+ +E ++V +E L E + + ++ +K++E E +L
Sbjct: 1414 RKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEE----QL 1469
Query: 861 RSAKKASALSDASR-KWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLN 916
++ L R + FL++E + + ++E R Q E + L QL+
Sbjct: 1470 LQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQ-EPERKFLEEEQQLH 1525
Score = 42.7 bits (99), Expect = 0.002
Identities = 69/289 (23%), Positives = 124/289 (42%), Gaps = 40/289 (13%)
Query: 690 QERERIRNDELDYLRE------RQTVEDMQAKVDQQ---RVEDEAWYQKQELLRKAEETR 740
QERER +E LR+ R+ + +Q + +QQ + D + ++++ LR+ E R
Sbjct: 1442 QERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDR 1501
Query: 741 R----EMLLQE-EEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRL 795
+ E+ QE E K +++ Q+L +R+ K + ++ RR + QQ +Q+ + +
Sbjct: 1502 KFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQ---EEQQLRRQERGQQRRQDRDRKFR 1558
Query: 796 DDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEG 855
++E R+ E Q L+++ R RK LEE + E + Q+ + EG
Sbjct: 1559 EEEQLRQEREEQQ--LSRQER------DRKFRLEEQKVRRQ-EQERKFMEDEQQLRRQEG 1609
Query: 856 KEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHK---EEPRFQNEQDSSCLPRT 912
++ +LR + D L QE H + K EEP+ + ++ R
Sbjct: 1610 QQ-QLRQERDRKFREDEQ----LLQEREEQQLHRQERDRKFLEEEPQLRRQE------RE 1658
Query: 913 SQLNDSSEMDPSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHR 961
QL + + L + E Q +K R Q+L + R R
Sbjct: 1659 QQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERER 1707
Score = 42.0 bits (97), Expect = 0.003
Identities = 62/280 (22%), Positives = 113/280 (40%), Gaps = 35/280 (12%)
Query: 686 DYQTQERERIRNDELDYLRERQTVEDMQAKVDQQR------VEDEAWYQKQELLRKAEET 739
+ Q QE ER + + + R QA+ +R Q++ LR E
Sbjct: 745 ELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQ 804
Query: 740 RREM-LLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQD----QQEMELRR 794
+RE L EEE+ Q+R++ ++EL+ E Q R R +LQ++ Q++ E RR
Sbjct: 805 QREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRR 864
Query: 795 -------------LDDEIGRKNLT-ENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAG 840
L++E R+ T + AL +++R + + + EE + + E
Sbjct: 865 SQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEE---EEELQREEREKR 921
Query: 841 ETQSQKTQKWKE---AEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEE 897
Q Q+ Q +E + +E LR ++ + R++ +++ + E EE
Sbjct: 922 RRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKL----QQKEEQLLGEE 977
Query: 898 PRFQNEQDSSCLPRTSQLNDSSEMDPSTQISLNRRAVEWD 937
P + Q+ R + E + RR EW+
Sbjct: 978 PEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWE 1017
Score = 38.9 bits (89), Expect = 0.024
Identities = 66/290 (22%), Positives = 118/290 (40%), Gaps = 35/290 (12%)
Query: 690 QERERIRNDELD-YLRERQTVEDMQAKVDQQR--VEDEAWYQKQELLRKAEETRREMLLQ 746
QE ++ R + D L E Q + +Q+R E E +KQE L + + RR+ L
Sbjct: 115 QEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELW 174
Query: 747 EEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQ-----EMELRRLDDEIGR 801
+ + Q+R+ E + +E LQ + ++Q +ELRR E +
Sbjct: 175 RQRQEWQERE-------ERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQ 227
Query: 802 KNLTENQEAL-----AKEMRADADAYRR---KVDLEEHMFHKLIEAGETQSQKTQKW--- 850
+ E Q+ + KE R R+ K+ EE + ++ E Q +K ++
Sbjct: 228 QQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELR 287
Query: 851 ---KEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSS 907
+E E ++ RLR ++ + R+ ++E E E + E + + EQ+
Sbjct: 288 RERQEEEQQQQRLRREQQLRRKQEEERR-EQQEERREQQERREQQEERREQQLRREQEER 346
Query: 908 CLPRTSQLNDSSEMDPSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLTAR 957
R QL E + Q RR E + Q L ++ + R++ R
Sbjct: 347 ---REQQLRREQEEERREQ--QLRREQEEERREQQLRREQQLRREQQLRR 391
Score = 37.7 bits (86), Expect = 0.053
Identities = 41/224 (18%), Positives = 102/224 (45%), Gaps = 14/224 (6%)
Query: 688 QTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQE 747
Q E +++R E D + + + + +++ +++E ++QEL RK E E L QE
Sbjct: 1677 QEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFRE--EEQLRQE 1734
Query: 748 -EEKMIQQRQRLAAVKRELKVK----EMHLQDAAR-RRFLKLQQDQQEMELRRLDDEIGR 801
E++ +++++R + E +++ E L+ R R+F + +Q +QE E ++L +
Sbjct: 1735 TEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESD 1794
Query: 802 KNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFRLR 861
+ E + ++R + + + + + + E + + Q+ Q+ ++ +++R
Sbjct: 1795 RKFREEE-----QLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQE-QRLRQERDRQYRAE 1848
Query: 862 SAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQD 905
S + ++E + E +E R Q +++
Sbjct: 1849 EQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEE 1892
Score = 35.8 bits (81), Expect = 0.20
Identities = 28/108 (25%), Positives = 58/108 (53%), Gaps = 12/108 (11%)
Query: 688 QTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEA--WYQKQELLRKAEETRREMLL 745
Q +E +++R + D + R E +Q + +QR+ E Y+ +E E++RR
Sbjct: 1805 QEREEQQLRPQQRDG-KYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRR---- 1859
Query: 746 QEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELR 793
EE+++ Q+ ++ +RE K++E H+ RR+ + Q+ +Q E++
Sbjct: 1860 -EEQELWQEEEQKRRQERERKLREEHI----RRQQKEEQRHRQVGEIK 1902
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 60.5 bits (145), Expect = 8e-09
Identities = 67/260 (25%), Positives = 112/260 (43%), Gaps = 18/260 (6%)
Query: 650 METTPTDIHPDSMLNVFVALTKGQYPVFNQYPKFIVDYQTQERERIRNDELDYLRERQTV 709
M TPT P S++ F+ K P+ V+ + Q E +R E RQ V
Sbjct: 504 MLMTPTSA-PRSVMKSFI---KRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKV 559
Query: 710 EDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRLAAV-KRELKVK 768
E+ D++R +E +++E LRK + R + +EEK Q Q+ A + ++ K K
Sbjct: 560 EE-----DKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAK 614
Query: 769 EMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKNLTENQEALAKEMRADADAYRRKVDL 828
E L + ++ ++ +E+E RR +E R+ QE +E R + ++K +
Sbjct: 615 EERLAEEKAKKKAAAKK-MEEVEARRKQEEEARRLRWLQQE---EEERRHQELLQKKKEE 670
Query: 829 EEHMFHKLIEAGETQSQKTQKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVE- 887
E+ K EA Q+ Q+ +E E +E R ++ + +QE E
Sbjct: 671 EQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQER 730
Query: 888 -HAENPCHKEEP--RFQNEQ 904
AE + E R Q EQ
Sbjct: 731 LQAERELQEREKALRLQKEQ 750
Score = 53.5 bits (127), Expect = 9e-07
Identities = 47/195 (24%), Positives = 100/195 (51%), Gaps = 18/195 (9%)
Query: 685 VDYQTQE--RERIRNDELDYLRERQTVEDMQAKVDQQRVEDEA----WYQKQELLRKAEE 738
+D +T++ ER+ ++ + +E+++A+ Q E+EA W Q++E EE
Sbjct: 606 IDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQ---EEEARRLRWLQQEE-----EE 657
Query: 739 TRREMLLQEEEKMIQQRQRLAA-VKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDD 797
R + LLQ++++ Q+R R AA KR + +E ++ RR + +Q+++E E R +
Sbjct: 658 RRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQER 717
Query: 798 EIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKE 857
++ + QE L E + + + L++ + +E + + ++ Q+ E + +E
Sbjct: 718 QLAEQERRREQERLQAE--RELQEREKALRLQKEQLQRELEE-KKKKEEQQRLAERQLQE 774
Query: 858 FRLRSAKKASALSDA 872
+ + AK+A+ S A
Sbjct: 775 EQEKKAKEAAGASKA 789
Score = 52.8 bits (125), Expect = 2e-06
Identities = 39/146 (26%), Positives = 76/146 (52%), Gaps = 7/146 (4%)
Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEE 749
QE E R+ EL ++ + E ++ + +R+ ++ +++E R+ +E RRE +E+E
Sbjct: 653 QEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQE-RREQERREQE 711
Query: 750 KMIQQRQRLAAVKRELKVK---EMHLQDAARRRFLKLQQDQQEMELRRLDDE---IGRKN 803
+ Q+RQ +R + + E LQ+ + L+ +Q Q+E+E ++ +E + +
Sbjct: 712 RREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQ 771
Query: 804 LTENQEALAKEMRADADAYRRKVDLE 829
L E QE AKE + A VD++
Sbjct: 772 LQEEQEKKAKEAAGASKALNVTVDVQ 797
Score = 37.7 bits (86), Expect = 0.053
Identities = 32/123 (26%), Positives = 60/123 (48%), Gaps = 8/123 (6%)
Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEE 749
++RE+ R ++ +ER+ Q + +Q+R E E +QE R+ E + E LQE E
Sbjct: 686 EQREQERREQERREQERRE----QERREQERREQERQLAEQERRREQERLQAERELQERE 741
Query: 750 KMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKNLTENQE 809
K ++ ++ + E K K+ Q A R+ Q++QE + + N+T + +
Sbjct: 742 KALRLQKEQLQRELEEKKKKEEQQRLAERQL----QEEQEKKAKEAAGASKALNVTVDVQ 797
Query: 810 ALA 812
+ A
Sbjct: 798 SPA 800
Score = 32.7 bits (73), Expect = 1.7
Identities = 39/195 (20%), Positives = 87/195 (44%), Gaps = 9/195 (4%)
Query: 777 RRRFLKLQQDQQEMELRRLD-DEIGRKNLTE----NQEALAKEMRADADAYRRKVDLEEH 831
R+R L++ ++ +LRR +E R+ L E +E L K ++A + K + ++
Sbjct: 539 RQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQ 598
Query: 832 MFHKLIEAGETQSQKTQKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAEN 891
+ K + E +++K ++ + AE K + +AKK + ++ + + + E
Sbjct: 599 IEQKFAQIDE-KTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEE 657
Query: 892 PCHKEEPRFQNEQDSSCLPRTSQ---LNDSSEMDPSTQISLNRRAVEWDTTGQNLIKKVR 948
H+E + + E++ L + ++ L + E + Q + E + Q ++ R
Sbjct: 658 RRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQER 717
Query: 949 NLRQRLTARARHRCQ 963
L ++ R + R Q
Sbjct: 718 QLAEQERRREQERLQ 732
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 60.1 bits (144), Expect = 1e-08
Identities = 55/220 (25%), Positives = 99/220 (45%), Gaps = 9/220 (4%)
Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEE 749
+E+ER R + L E + + + + D++R +E +++E LRK + R + +EE
Sbjct: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 590
Query: 750 KMIQQRQRLAAV-KRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKNLTENQ 808
K Q Q+ A + ++ K KE L + ++ ++ +E+E RR +E R+ Q
Sbjct: 591 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKK-MEEVEARRKQEEEARRLRWLQQ 649
Query: 809 EALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFRLRSAKKASA 868
E +E R + ++K + E+ K EA Q+ Q+ +E E +E R ++
Sbjct: 650 E---EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQ 706
Query: 869 LSDASRKWFLKQEINAAVE--HAENPCHKEEP--RFQNEQ 904
+ +QE E AE + E R Q EQ
Sbjct: 707 ERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQ 746
Score = 53.5 bits (127), Expect = 9e-07
Identities = 47/195 (24%), Positives = 100/195 (51%), Gaps = 18/195 (9%)
Query: 685 VDYQTQE--RERIRNDELDYLRERQTVEDMQAKVDQQRVEDEA----WYQKQELLRKAEE 738
+D +T++ ER+ ++ + +E+++A+ Q E+EA W Q++E EE
Sbjct: 602 IDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQ---EEEARRLRWLQQEE-----EE 653
Query: 739 TRREMLLQEEEKMIQQRQRLAA-VKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDD 797
R + LLQ++++ Q+R R AA KR + +E ++ RR + +Q+++E E R +
Sbjct: 654 RRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQER 713
Query: 798 EIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKE 857
++ + QE L E + + + L++ + +E + + ++ Q+ E + +E
Sbjct: 714 QLAEQERRREQERLQAE--RELQEREKALRLQKEQLQRELEE-KKKKEEQQRLAERQLQE 770
Query: 858 FRLRSAKKASALSDA 872
+ + AK+A+ S A
Sbjct: 771 EQEKKAKEAAGASKA 785
Score = 52.8 bits (125), Expect = 2e-06
Identities = 39/146 (26%), Positives = 76/146 (52%), Gaps = 7/146 (4%)
Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEE 749
QE E R+ EL ++ + E ++ + +R+ ++ +++E R+ +E RRE +E+E
Sbjct: 649 QEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQE-RREQERREQE 707
Query: 750 KMIQQRQRLAAVKRELKVK---EMHLQDAARRRFLKLQQDQQEMELRRLDDE---IGRKN 803
+ Q+RQ +R + + E LQ+ + L+ +Q Q+E+E ++ +E + +
Sbjct: 708 RREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQ 767
Query: 804 LTENQEALAKEMRADADAYRRKVDLE 829
L E QE AKE + A VD++
Sbjct: 768 LQEEQEKKAKEAAGASKALNVTVDVQ 793
Score = 37.7 bits (86), Expect = 0.053
Identities = 32/123 (26%), Positives = 60/123 (48%), Gaps = 8/123 (6%)
Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEE 749
++RE+ R ++ +ER+ Q + +Q+R E E +QE R+ E + E LQE E
Sbjct: 682 EQREQERREQERREQERRE----QERREQERREQERQLAEQERRREQERLQAERELQERE 737
Query: 750 KMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKNLTENQE 809
K ++ ++ + E K K+ Q A R+ Q++QE + + N+T + +
Sbjct: 738 KALRLQKEQLQRELEEKKKKEEQQRLAERQL----QEEQEKKAKEAAGASKALNVTVDVQ 793
Query: 810 ALA 812
+ A
Sbjct: 794 SPA 796
Score = 34.3 bits (77), Expect = 0.58
Identities = 42/211 (19%), Positives = 95/211 (45%), Gaps = 10/211 (4%)
Query: 761 VKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLD-DEIGRKNLTE----NQEALAKEM 815
+KR ++ M ++ R+R L++ ++ +LRR +E R+ L E +E L K +
Sbjct: 520 IKRNTPLR-MDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVL 578
Query: 816 RADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFRLRSAKKASALSDASRK 875
+A + K + ++ + K + E +++K ++ + AE K + +AKK + ++
Sbjct: 579 QARERVEQMKEEKKKQIEQKFAQIDE-KTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQ 637
Query: 876 WFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQ---LNDSSEMDPSTQISLNRR 932
+ + + E H+E + + E++ L + ++ L + E + Q +
Sbjct: 638 EEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQE 697
Query: 933 AVEWDTTGQNLIKKVRNLRQRLTARARHRCQ 963
E + Q ++ R L ++ R + R Q
Sbjct: 698 RREQERREQERREQERQLAEQERRREQERLQ 728
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 58.5 bits (140), Expect = 3e-08
Identities = 51/236 (21%), Positives = 110/236 (46%), Gaps = 25/236 (10%)
Query: 691 ERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQEL------LRKAEET--RRE 742
E+ I+ + + R+ + + + +V +++E W Q++EL +RK EE R+E
Sbjct: 240 EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQE 299
Query: 743 MLLQE--------EEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRR 794
L+E EEKM +Q +RL ++EL+ +E L++ R + Q +QE ++
Sbjct: 300 ERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWE 359
Query: 795 LDDEI--GRKNLTENQEALAKEMRADADAYRRKVDLEEHMF---HKLIEAGETQSQKTQK 849
++++ + + +E L ++ + + ++ D EE M+ +L E E ++ +
Sbjct: 360 QEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKM 419
Query: 850 WKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQD 905
W++ E ++R KK +R K + + E +EE + +++
Sbjct: 420 WEQVE----KMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEE 471
Score = 52.8 bits (125), Expect = 2e-06
Identities = 46/193 (23%), Positives = 95/193 (49%), Gaps = 21/193 (10%)
Query: 677 FNQYPKFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKA 736
++Q K + + +ERE+ +E + +RE++ E MQ + ++ + ++E ++++E +++
Sbjct: 579 WDQEEKMREEERMREREKKMREEEEMMREQE--EKMQEQEEKMQEQEEKMWEQEEKMQEQ 636
Query: 737 EETRREMLLQEEEKMIQQ------RQRLAAVKREL----KVKEMHLQDAARRRFL---KL 783
EE + ++EEKM +Q +QRL K +L K++E + K+
Sbjct: 637 EEK----MWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKM 692
Query: 784 QQDQQEMELRRLDDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQ 843
++ QE E + D E R+ E+ K+MR + + R + + + K+ E E
Sbjct: 693 EKKTQEQEKKTWDQEKMREE--ESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEM 750
Query: 844 SQKTQKWKEAEGK 856
++ +K E E K
Sbjct: 751 WEQEEKMWEQEEK 763
Score = 51.6 bits (122), Expect = 4e-06
Identities = 57/281 (20%), Positives = 126/281 (44%), Gaps = 26/281 (9%)
Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRV----EDEAWYQKQELLRKAEETRREMLL 745
QE ERIR E E +T+ + + K+ +Q ++E +Q+Q L + E+ + +
Sbjct: 447 QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKM 506
Query: 746 QEEEKMIQQRQRLAAVKREL--KVKEMHLQDAARRRFLKLQQDQQEM---ELRRLDDEIG 800
QE+E+ I +++ + E+ + K+M Q+ R + ++ + +++M E + D E
Sbjct: 507 QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER 566
Query: 801 RKNLTENQEALA----KEMRADADAYRR--KVDLEEHMFHKLIEAGETQSQKTQKWKEAE 854
+ T+ QE ++MR + R K+ EE M + E + Q +K Q+ +E
Sbjct: 567 MEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKM 626
Query: 855 GKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEE--PRFQNEQDSSCLPRT 912
++ ++ + W ++++ E P KE+ + ++ +
Sbjct: 627 WEQEEKMQEQEEKMWEQEEKMWEQEEKM---WEQQRLPEQKEKLWEHEKMQEQEKMQEQE 683
Query: 913 SQLNDSSEMDPSTQISLNRRAVEWDTTGQNLIKKVRNLRQR 953
++ + +M+ TQ + WD Q +++ ++R+R
Sbjct: 684 EKIWEQEKMEKKTQ---EQEKKTWD---QEKMREEESMRER 718
Score = 48.9 bits (115), Expect = 2e-05
Identities = 35/224 (15%), Positives = 106/224 (47%), Gaps = 9/224 (4%)
Query: 688 QTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETR--REMLL 745
+ +E++ +R E + + + + + K+ +Q E++ W Q++ L + ++ R + +
Sbjct: 336 ELREQKELREQEEQMQEQEEKMWEQEEKMREQ--EEKMWRQEERLWEQEKQMREQEQKMR 393
Query: 746 QEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKNLT 805
+EE+M +Q +RL + ++ +E + + R K Q+Q++ + + + +
Sbjct: 394 DQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIR 453
Query: 806 ENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQ---SQKTQKWKEAEGKEFRLRS 862
E ++ + +E + + EE+M+ + + + Q QK + W++ + +E +
Sbjct: 454 EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKI 513
Query: 863 AKKASALSDASRKWFLKQEI--NAAVEHAENPCHKEEPRFQNEQ 904
++ + D W ++++ + E+ ++E + ++++
Sbjct: 514 WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE 557
Score = 48.1 bits (113), Expect = 4e-05
Identities = 40/216 (18%), Positives = 98/216 (45%), Gaps = 12/216 (5%)
Query: 692 RERIRNDELDYLRERQTVEDMQAKV--DQQRVEDEAWYQKQELLRKAEETRREMLLQEEE 749
+E++R E + + + D + K+ ++R+E + Q+++ + E+ R E ++E E
Sbjct: 536 QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRERE 595
Query: 750 KMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKNLTENQE 809
K +++ + + + E ++ + + ++ QE E + + E + + E +E
Sbjct: 596 KKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQE---EKMWEQEE 652
Query: 810 ALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFRLRSAKKASAL 869
+ ++ R +K L EH K+ E + Q Q+ + W E E E + + +K +
Sbjct: 653 KMWEQQRLP----EQKEKLWEH--EKMQEQEKMQEQEEKIW-EQEKMEKKTQEQEKKTWD 705
Query: 870 SDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQD 905
+ R+ +E + E ++E + Q +++
Sbjct: 706 QEKMREEESMREREKKMREEEEMMREQEEKMQEQEE 741
Score = 47.8 bits (112), Expect = 5e-05
Identities = 36/180 (20%), Positives = 92/180 (51%), Gaps = 12/180 (6%)
Query: 685 VDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREM- 743
++ +TQE+E+ D+ + +RE + + + + K+ R E+E +++E +++ EE +E
Sbjct: 567 MEKKTQEQEKKTWDQEEKMREEERMREREKKM---REEEEMMREQEEKMQEQEEKMQEQE 623
Query: 744 --LLQEEEKMIQQRQRL-----AAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLD 796
+ ++EEKM +Q +++ ++E K+ E + + + ++ Q++ +++ +
Sbjct: 624 EKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQE 683
Query: 797 DEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGK 856
++I + E + ++ D + R + + E K+ E E ++ +K +E E K
Sbjct: 684 EKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRERE-KKMREEEEMMREQEEKMQEQEEK 742
Score = 44.7 bits (104), Expect = 4e-04
Identities = 44/232 (18%), Positives = 103/232 (44%), Gaps = 23/232 (9%)
Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEE 749
++ +R+R E + + + + + + + R ++E +++E + + EE RE +EE
Sbjct: 318 RQEKRLREQEKELREQEKELREQK----ELREQEEQMQEQEEKMWEQEEKMRE----QEE 369
Query: 750 KMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKNLTENQE 809
KM +Q +RL +++++ +E ++D R + +Q+ LR ++ + + Q
Sbjct: 370 KMWRQEERLWEQEKQMREQEQKMRDQEERMW------EQDERLREKEERMREQEKMWEQV 423
Query: 810 ALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFRLRSAKKASAL 869
+E + + ++ D EE M E + +K + +E +E + K+ +
Sbjct: 424 EKMREEKKMQEQEKKTRDQEEKMQE---EERIREREKKMREEEETMREQEEKMQKQEENM 480
Query: 870 SDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSSEM 921
+ K + +Q + E E +E+ EQ+ + ++ D EM
Sbjct: 481 WEQEEKEWQQQRL---PEQKEKLWEQEK---MQEQEEKIWEQEEKIRDQEEM 526
Score = 43.5 bits (101), Expect = 0.001
Identities = 41/242 (16%), Positives = 110/242 (45%), Gaps = 26/242 (10%)
Query: 698 DELDYLRERQTVEDMQAKVDQQ----RVEDEAWYQ-----KQELLRKAEE---TRREMLL 745
++ + L E++ +++ + K+ +Q R ++E W Q +QE +R+ E+ + E +
Sbjct: 495 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 554
Query: 746 QEEEKMIQQRQRLAAVKRELKVK------EMHLQDAARRRFLKLQQDQQEMELRRLDDEI 799
+E+KM Q +R+ +E + K +M ++ R R K++++++ M + +
Sbjct: 555 DQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQE 614
Query: 800 GRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFR 859
+ + E +E + ++ + + + EE M+ + E + + Q+ E + K +
Sbjct: 615 QEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ-----EEKMWEQQRLPEQKEKLWE 669
Query: 860 LRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSS 919
++ + + K + ++++ + E +E + ++ S R ++ +
Sbjct: 670 HEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQE---KMREEESMREREKKMREEE 726
Query: 920 EM 921
EM
Sbjct: 727 EM 728
Score = 39.7 bits (91), Expect = 0.014
Identities = 35/215 (16%), Positives = 98/215 (45%), Gaps = 8/215 (3%)
Query: 691 ERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEEK 750
E E+++ E +E + E + + Q E + W Q++ ++ R + + +EEE
Sbjct: 669 EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEM 728
Query: 751 MIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKNLTENQEA 810
M +Q +++ + +++ +E + + + + +Q+++ E +RL ++ ++ L E+++
Sbjct: 729 MREQEEKMQEQEEKMQEQEEEMWEQEEKMW---EQEEKMWEQQRLPEQ--KEKLWEHEKM 783
Query: 811 LAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFRLRSAKKASALS 870
+E + + R D EE M E Q +K + +E + ++
Sbjct: 784 QEQEKIWEQEEKMR--DQEEKM-RGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWG 840
Query: 871 DASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQD 905
+ W ++++ ++ E ++E + + +++
Sbjct: 841 QEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEE 875
Score = 38.5 bits (88), Expect = 0.031
Identities = 38/229 (16%), Positives = 102/229 (44%), Gaps = 12/229 (5%)
Query: 688 QTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEET-----RRE 742
Q QE + +E + +E + E + ++++ + Q+QE +++ EE + E
Sbjct: 634 QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKME 693
Query: 743 MLLQEEEKMI--QQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIG 800
QE+EK Q++ R RE + K ++ R + K+Q+ +++M+ + +
Sbjct: 694 KKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQ 753
Query: 801 RKNLTENQEALAKEMRADADAYR----RKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGK 856
+ + E +E + ++ R + K+ +E ++ + + + + + + ++ G+
Sbjct: 754 EEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQ 813
Query: 857 EFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQD 905
E ++R ++ + W ++++ E K E + Q +++
Sbjct: 814 EEKMR-GQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEE 861
Score = 35.4 bits (80), Expect = 0.26
Identities = 45/239 (18%), Positives = 111/239 (46%), Gaps = 24/239 (10%)
Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRV---EDEAWYQKQELLRKAE--ETRREML 744
++ ER+R E + +RE++ + + K+ +++ +++ ++E +++ E R + +
Sbjct: 401 EQDERLREKE-ERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKM 459
Query: 745 LQEEEKMIQQRQRLAAVKR---ELKVKEMHLQDAARRRFLKLQQD----------QQEME 791
+EEE M +Q +++ + E + KE Q ++ +Q+ +QE +
Sbjct: 460 REEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 519
Query: 792 LRRLDDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMF---HKLIEAGETQSQKTQ 848
+R ++ G++ QE + ++ + + D E+ M+ ++ + + Q +KT
Sbjct: 520 IRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTW 579
Query: 849 KWKEAEGKEFRLRS-AKKASALSDASRKWFLK-QEINAAVEHAENPCHKEEPRFQNEQD 905
+E +E R+R KK + R+ K QE ++ E ++E + Q +++
Sbjct: 580 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEE 638
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 58.5 bits (140), Expect = 3e-08
Identities = 51/246 (20%), Positives = 109/246 (44%), Gaps = 30/246 (12%)
Query: 688 QTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQE 747
+T E ERI + + R +Q V D+ K ++++ ++EL RK +E ++ LQ
Sbjct: 446 KTSEEERISLQQ-ELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKK--LQT 502
Query: 748 EEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDD-EIGRKNLTE 806
E+ Q++ ++A K ++ +LK+ Q++++ E L++ E+ +K +
Sbjct: 503 REREFQEQMKVALEK-------------SQSEYLKISQEKEQQESLALEELELQKKAILT 549
Query: 807 NQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAE----GKEFRLRS 862
E ++++ +A+ YR ++ E K ++ + QS+ EAE KE +
Sbjct: 550 ESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMV 609
Query: 863 AKKASALSDASRK----W-----FLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTS 913
K + L + W LKQ+ +E C +E+ +++
Sbjct: 610 EKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIE 669
Query: 914 QLNDSS 919
++N+ +
Sbjct: 670 EMNEKT 675
Score = 36.2 bits (82), Expect = 0.15
Identities = 54/277 (19%), Positives = 117/277 (42%), Gaps = 65/277 (23%)
Query: 687 YQTQERERIRNDELDYLRERQTVEDMQAKVDQQR-----------VEDEAWYQKQELLRK 735
++ +E + D+ D +++ +++AK+D+Q+ E E Q+ E K
Sbjct: 701 HKLEEELSVLKDQTDKMKQ-----ELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALK 755
Query: 736 AEETRREMLLQEEEKMIQQRQ-RLAAVKRELKVKEMHLQDA------------ARRRFLK 782
+ + E+LL+E +K +++ Q + ++ ++K E LQ A A K
Sbjct: 756 DQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTK 815
Query: 783 LQQDQ-QEMELRRLDDEIGRKNLTE---NQEALAKEMRADADAYR--------------- 823
++Q +++ + LD E R LT+ EA K++ + DA++
Sbjct: 816 AYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNS 875
Query: 824 ---RKVDLEEHMFHKLIEAGETQSQKTQ-----------KWKEAEGKEFRLRSAKKASAL 869
+KV ++ +E G + ++T+ + +E + KE + + +K SA
Sbjct: 876 EMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILT-QKLSAK 934
Query: 870 SDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDS 906
D+ L +E ++ E K + + + Q++
Sbjct: 935 EDSIH--ILNEEYETKFKNQEKKMEKVKQKAKEMQET 969
Score = 36.2 bits (82), Expect = 0.15
Identities = 45/224 (20%), Positives = 93/224 (41%), Gaps = 24/224 (10%)
Query: 687 YQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEE----TRRE 742
Y + + EL+++ ++ + K + R+E E+ + EL RKAE+ +++
Sbjct: 1595 YSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQ 1654
Query: 743 MLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRK 802
+L Q EEK Q + K E HL + L + ++E E+ L++++
Sbjct: 1655 LLSQMEEKEEQYK----------KGTESHLSE------LNTKLQEREREVHILEEKLKSV 1698
Query: 803 NLTENQEALAKEMRADADAYRRKVDLE-EHMFHKLIEAGETQSQKTQKWKEAEGKEFRLR 861
++++ + + AY + + + + K E + Q+ KE K +
Sbjct: 1699 ESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKE---KLLQRV 1755
Query: 862 SAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQD 905
+K +S QE +EHAE H+++ + Q+
Sbjct: 1756 GQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQE 1799
Score = 35.0 bits (79), Expect = 0.34
Identities = 47/253 (18%), Positives = 111/253 (43%), Gaps = 12/253 (4%)
Query: 703 LRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRLAAVK 762
L E T E ++ + Q ++ Q +L K RE +E + Q+ K
Sbjct: 1899 LLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRK 1958
Query: 763 RELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKNLTENQEALAKEMRADADAY 822
+ E+ ++ + R K++Q+Q+++EL+ + ++ + E LA++ +
Sbjct: 1959 EHQQELEILKKEYDQEREEKIKQEQEDLELKH--NSTLKQLMREFNTQLAQKEQELEMTI 2016
Query: 823 RRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEI 882
+ ++ + + +L+E+ + ++ + K K AE + R+AK+ + DA ++E+
Sbjct: 2017 KETINKAQEVEAELLESHQEETNQLLK-KIAEKDDDLKRTAKRYEEILDAR-----EEEM 2070
Query: 883 NAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSSEMDPSTQISLNRRAV-EWDTTGQ 941
A V + + + ++Q + + P + + M+ TQ++ + + Q
Sbjct: 2071 TAKVRDLQTQLEELQKKYQQKLEQEENPGNDNV---TIMELQTQLAQKTTLISDSKLKEQ 2127
Query: 942 NLIKKVRNLRQRL 954
+++ NL RL
Sbjct: 2128 EFREQIHNLEDRL 2140
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 57.8 bits (138), Expect = 5e-08
Identities = 45/217 (20%), Positives = 107/217 (49%), Gaps = 14/217 (6%)
Query: 688 QTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQE 747
Q Q++E ++ + +R+++ E M + +Q + ++E +++E +RK EE RE +
Sbjct: 214 QMQKQEEQMGEQEEQMRKQE--EQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMRE----Q 267
Query: 748 EEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKNLTEN 807
EE+M +Q +++ K + + +E + + R + Q +QE ++R +++ + E
Sbjct: 268 EEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQ-----MREQ 322
Query: 808 QEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFRLRSAKKAS 867
+E + K+ + + + +E M+ + + GE + Q ++ ++ +E ++R ++
Sbjct: 323 EEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQM 382
Query: 868 ALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQ 904
+ + KQE + + KE+ R Q EQ
Sbjct: 383 RKQEEQMR---KQEEQMGEQKEQMGEQKEQMREQEEQ 416
Score = 45.4 bits (106), Expect = 3e-04
Identities = 32/153 (20%), Positives = 81/153 (52%), Gaps = 19/153 (12%)
Query: 688 QTQERERIRNDELDYLRE-----RQTVEDMQAKVDQQ-RVEDEAWYQKQELLRKAEETRR 741
QT E+E ++ + +RE R+ E M+ + +Q + E++ W QK+++ ++
Sbjct: 290 QTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWE-----QK 344
Query: 742 EMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIG- 800
E + ++EE+M +Q +++ + +++ +E + R + Q +QE ++R+ ++++G
Sbjct: 345 EQMWKQEEQMGEQEEQMQKQEEQVRKQEEQM------RKQEEQMRKQEEQMRKQEEQMGE 398
Query: 801 -RKNLTENQEALAKEMRADADAYRRKVDLEEHM 832
++ + E +E + ++ + + EEHM
Sbjct: 399 QKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHM 431
Score = 44.3 bits (103), Expect = 6e-04
Identities = 46/217 (21%), Positives = 95/217 (43%), Gaps = 14/217 (6%)
Query: 688 QTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQE 747
Q +E+E ++ + E++ E M + +Q + ++E +++E +RK EE E QE
Sbjct: 186 QVREQEGQMGEQEGQMGEQE--EQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGE---QE 240
Query: 748 EEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKNLTEN 807
E+ Q+ Q K+E ++M Q+ R + ++Q+E L++ + + E
Sbjct: 241 EQVQKQEEQ---VQKQE---EQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQ 294
Query: 808 QEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFRLRSAKKAS 867
+E + ++ + + + EE M + + G+ Q+ Q W++ E + K
Sbjct: 295 EEQMREQEEQMREQEEQMREQEEQMREQEEQMGK---QEEQMWEQKEQMWEQKEQMWKQE 351
Query: 868 ALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQ 904
+ KQE + + +E+ R Q EQ
Sbjct: 352 EQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQ 388
Score = 30.4 bits (67), Expect = 8.4
Identities = 29/128 (22%), Positives = 60/128 (46%), Gaps = 5/128 (3%)
Query: 730 QELLRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQE 789
+EL K E + E+ L E EK + + + +KR+L+ ++ L + R + Q +QE
Sbjct: 7 EELKEKNAELQEELQLVETEKS-EIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQE 65
Query: 790 MELRRLDDEI-GRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQ 848
++R + ++ ++ QE +E +V +E + + G+ + Q+ Q
Sbjct: 66 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE--QEGQVREQEGQ 123
Query: 849 KWKEAEGK 856
+E EG+
Sbjct: 124 V-REQEGQ 130
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 57.8 bits (138), Expect = 5e-08
Identities = 61/298 (20%), Positives = 114/298 (38%), Gaps = 17/298 (5%)
Query: 42 VLRFLNVAFDGTGDCLIAGDHQGNIYVFDL-HGNRFNLVQRTAQACTALAFNLRRKSEFL 100
+L NVA + +G C I G + ++D G N ++ A+AFN +
Sbjct: 92 ILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKIA 151
Query: 101 VALADYSIKCFDTVTKELVSWMRGHESSVFSISVHASGKYAITTSSD-TAQLWDLDTFQR 159
D + K + T + RGH + + +S + T S D TA+LWD+ +
Sbjct: 152 TGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEE 211
Query: 160 KRKLNIRQSVGIQKVFFLPLSNTILSCFKDNSIFAWECDT-LFCKYQLPAPPESSSILYK 218
L S I + F + I++ D+++ W+ DT + E SS +
Sbjct: 212 VYTLR-GHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASF- 269
Query: 219 VFAVTRDGRILAAGGKSNHLHLWCLEARQLFRIIQMPTKVRAIRHLEFLPDSFDAGSNQV 278
D ++ G LW + + H + + DS + ++
Sbjct: 270 ----NWDCSLILTGSMDKTCKLWDATNGKCVATL--------TGHDDEILDSCFDYTGKL 317
Query: 279 LGVLSQDGIMRFINMQTCKLLFEIGSLDEGISSSAISPHGRYIASIMENGSLNIYSVQ 336
+ S DG R + T K + ++ + IS + +P G ++ + + + I+ Q
Sbjct: 318 IATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQ 375
Score = 55.8 bits (133), Expect = 2e-07
Identities = 49/201 (24%), Positives = 87/201 (43%), Gaps = 14/201 (6%)
Query: 46 LNVAFDGTGDCLIAGDHQGNIYVFDLH-GNRFNLVQRTAQACTALAFNLRRKSEFLVALA 104
++++F+ +GD +I G + V+D G + N++ ++ +FN S L
Sbjct: 223 ISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDC-SLILTGSM 281
Query: 105 DYSIKCFDTVTKELVSWMRGHESSVFSISVHASGKYAITTSSD-TAQLWDLDTFQRKRKL 163
D + K +D + V+ + GH+ + +GK T S+D TA+++ T + KL
Sbjct: 282 DKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKL 341
Query: 164 NIRQSVGIQKVFFLPLSNTILSCFKDNSIFAWECDTLFCKYQLPAPPE---SSSILYKVF 220
+ I K+ F P N +L+ D + W+ T C L + S + YK
Sbjct: 342 EGHEG-EISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYK-- 398
Query: 221 AVTRDGRILAAGGKSNHLHLW 241
G I+ G K N +W
Sbjct: 399 -----GNIVITGSKDNTCRIW 414
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 57.4 bits (137), Expect = 6e-08
Identities = 52/237 (21%), Positives = 116/237 (48%), Gaps = 27/237 (11%)
Query: 691 ERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQEL------LRKAEET--RRE 742
E+ I+ + + R+ + + + +V +++E W Q++EL +RK EE R+E
Sbjct: 202 EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQE 261
Query: 743 MLLQE--------EEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRR 794
L+E EEKM +Q +RL ++EL+ +E L++ + R + Q +QE ++
Sbjct: 262 ERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWE 321
Query: 795 LDDEI--GRKNLTENQEALAKEMRADADAYRRKVDLEEHMF---HKLIEAGETQSQKTQK 849
++++ + + +E L ++ + + ++ D EE M+ +L E E ++ +
Sbjct: 322 QEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKM 381
Query: 850 WKEAE--GKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQ 904
W++ E +E R+R +K + + ++++ + EN +EE +Q ++
Sbjct: 382 WEQEEKMQEEERIREREKKMREEEET----MREQEEKMQKQEENMWEQEEKEWQQQR 434
Score = 52.4 bits (124), Expect = 2e-06
Identities = 49/235 (20%), Positives = 110/235 (46%), Gaps = 21/235 (8%)
Query: 673 QYPVFNQYPKFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQEL 732
Q ++ Q K + +TQE+E+ D+ + +RE + + + + K+ R E+E +++E
Sbjct: 526 QKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKM---REEEEMMREQEEK 582
Query: 733 LRKAEETRREM---LLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRR---FLKLQQD 786
+++ EE RE + ++EEKM +Q +++ ++E K+ E +D + + + ++
Sbjct: 583 MQEQEEKMREQEEKMWEQEEKMQEQEEKM--WEQEEKMWEQEEEDKMQEQEEMMWEQEEK 640
Query: 787 QQEMELRRLDDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGE-TQSQ 845
QE E + + E + E ++M+ + R + + + K+ E E + Q
Sbjct: 641 MQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQ 700
Query: 846 KTQKWKEAE---GKEFRL----RSAKKASALSDASRKWFLKQEINAAVEHAENPC 893
+ + W + E G+E ++ +K + D K +++ + E PC
Sbjct: 701 EEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEK--MQERLPEHEERCSEPC 753
Score = 51.6 bits (122), Expect = 4e-06
Identities = 49/222 (22%), Positives = 101/222 (45%), Gaps = 15/222 (6%)
Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRV----EDEAWYQKQELLRKAEETRREMLL 745
QE ERIR E E +T+ + + K+ +Q ++E +Q+Q L + E+ + +
Sbjct: 389 QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKM 448
Query: 746 QEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQ-EMELRRLDDEIGRKNL 804
QE+E+ I +++ + E+ +E + R+ ++ Q+DQ E E + D E +
Sbjct: 449 QEQEEKIWEQEEKIRDQEEMWGQEKKMW---RQEKMREQEDQMWEQEEKMRDQEQKMWDQ 505
Query: 805 TENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAE--GKEFRLRS 862
E + +R + R + + + K+ E +TQ Q+ + W + E +E R+R
Sbjct: 506 EERMWEQDERLREKEERMREQKKMWQQE-EKMREEKKTQEQEKKTWDQEEKMREEERMRE 564
Query: 863 AKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQ 904
+K + ++++ E E +EE ++ E+
Sbjct: 565 REKKM----REEEEMMREQEEKMQEQEEKMREQEEKMWEQEE 602
Score = 49.3 bits (116), Expect = 2e-05
Identities = 40/213 (18%), Positives = 102/213 (47%), Gaps = 8/213 (3%)
Query: 698 DELDYLRERQTVEDMQAKVDQQ----RVEDEAWYQKQELLRKAEETRRE-MLLQEEEKMI 752
++ + L E++ +++ + K+ +Q R ++E W Q++++ R+ + +E + ++EEKM
Sbjct: 437 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 496
Query: 753 QQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKNLTENQEALA 812
Q Q++ + + ++ L++ R + + QQE ++R ++ T +QE
Sbjct: 497 DQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKM 556
Query: 813 KEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFRLRSAKKASALSDA 872
+E + +K+ EE M + E + Q +K ++ +E ++ ++
Sbjct: 557 REEERMRER-EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 615
Query: 873 SRKWFLKQEINAAVEHAENPCHKEEPRFQNEQD 905
+ W +QE ++ E ++E + Q +++
Sbjct: 616 EKMW--EQEEEDKMQEQEEMMWEQEEKMQEQEE 646
Score = 46.6 bits (109), Expect = 1e-04
Identities = 36/212 (16%), Positives = 103/212 (48%), Gaps = 20/212 (9%)
Query: 688 QTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETR--REMLL 745
+ +E++++R E + + + + + K+ +Q E++ W Q++ L + ++ R + +
Sbjct: 298 ELREQKKLREQEEQMQEQEEKMWEQEEKMREQ--EEKMWRQEERLWEQEKQMREQEQKMR 355
Query: 746 QEEEKMIQQRQRLAAVKRELKVKE--------MHLQDAARRRFLKLQQD-----QQEMEL 792
+EE+M +Q +RL + ++ +E M ++ R R K++++ +QE ++
Sbjct: 356 DQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKM 415
Query: 793 RRLDDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMF---HKLIEAGETQSQKTQK 849
++ ++ + + E Q+ E + + + EE ++ K+ + E Q+ +
Sbjct: 416 QKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKM 475
Query: 850 WKEAEGKEFRLRSAKKASALSDASRKWFLKQE 881
W++ + +E + ++ + D +K + ++E
Sbjct: 476 WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEE 507
Score = 46.6 bits (109), Expect = 1e-04
Identities = 43/230 (18%), Positives = 100/230 (43%), Gaps = 19/230 (8%)
Query: 688 QTQERERIRNDELDYLRER--QTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLL 745
Q QE +E ++ ++R + E + + Q E++ W Q++++ + E +E +
Sbjct: 416 QKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKM 475
Query: 746 QEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKNLT 805
+EKM +Q ++ + +++ +E + D R + +Q+ LR ++ + +
Sbjct: 476 WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMW------EQDERLREKEERMREQKKM 529
Query: 806 ENQEALAKEMRADADAYRRKVDLEEHMFH---------KLIEAGETQSQKTQKWKEAEGK 856
QE +E + + ++ D EE M K+ E E ++ +K +E E K
Sbjct: 530 WQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEK 589
Query: 857 --EFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQ 904
E + ++ + + K + ++E E + +EE ++ E+
Sbjct: 590 MREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEE 639
Score = 46.2 bits (108), Expect = 1e-04
Identities = 46/238 (19%), Positives = 111/238 (46%), Gaps = 19/238 (7%)
Query: 690 QERERIRNDELDYLRERQTVED--MQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQE 747
++ ER+R E + +E + E+ ++ + + R E+E +++E ++K EE + E
Sbjct: 370 EKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN-----MWE 424
Query: 748 EEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGR-KNLTE 806
+E+ Q+QRL K +L +E +Q+ + + + ++ + + E+ + ++ R + + E
Sbjct: 425 QEEKEWQQQRLPEQKEKLWEQE-KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 483
Query: 807 NQEALAKEMRADADAYRRKVDLEEHMF---HKLIEAGETQSQKTQKWKEAEGKEFRLRSA 863
++ + ++ D ++ D EE M+ +L E E ++ + W++ E ++R
Sbjct: 484 QEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEE----KMREE 539
Query: 864 KKASALSDASRKWFLKQEINAAVEHAENPCH-KEEPRFQNEQDSSCLPRTSQLNDSSE 920
KK + W ++++ E +EE EQ+ + ++ + E
Sbjct: 540 KKTQ--EQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE 595
Score = 40.0 bits (92), Expect = 0.011
Identities = 33/180 (18%), Positives = 89/180 (49%), Gaps = 13/180 (7%)
Query: 686 DYQTQERERIRNDELDYLRERQTV----EDMQAKVDQQRVEDEAWYQKQELLRKAEETRR 741
D ++ E++R+ E + + + E ++ K ++ R + + W Q++++ + + +
Sbjct: 486 DQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQ 545
Query: 742 EMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGR 801
E ++E+ +++ +R+ +RE K++E ++ R + K+Q+ +++M +
Sbjct: 546 EKKTWDQEEKMREEERMR--EREKKMREE--EEMMREQEEKMQEQEEKMREQEEKMWEQE 601
Query: 802 KNLTENQEAL--AKEMRADADAYRRKVDLEEHMF---HKLIEAGETQSQKTQKWKEAEGK 856
+ + E +E + +E + + + + EE M+ K+ E E ++ +K +E E K
Sbjct: 602 EKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEK 661
>gi|4557741 platelet-activating factor acetylhydrolase, isoform Ib,
alpha subunit [Homo sapiens]
Length = 410
Score = 56.6 bits (135), Expect = 1e-07
Identities = 51/252 (20%), Positives = 104/252 (41%), Gaps = 22/252 (8%)
Query: 97 SEFLVALADYSIKCFDTVTKELVSWMRGHESSVFSISVHASGKYAITTSSD-TAQLWDLD 155
S + A D +IK +D T + ++GH SV IS SGK + S+D T +LWD
Sbjct: 121 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 180
Query: 156 TFQRKRKLNIRQSVGIQKVFFLPLSNTILSCFKDNSIFAWECDTLFCKYQLPAPPESSSI 215
F+ R ++ + V +P + I+S +D +I WE T +C E
Sbjct: 181 GFECIRTMH-GHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHRE---- 235
Query: 216 LYKVFAVTRDGRILAAGGKSNHLHLWCLEARQLFRIIQMPTKVRAIRHLEFLPDSFDAGS 275
++ +DG ++A+ + +W + ++ ++ + + + P+S +
Sbjct: 236 WVRMVRPNQDGTLIASCSNDQTVRVWVVATKEC--KAELREHEHVVECISWAPESSYSSI 293
Query: 276 NQVLGVL--------------SQDGIMRFINMQTCKLLFEIGSLDEGISSSAISPHGRYI 321
++ G S+D ++ ++ T L + D + G++I
Sbjct: 294 SEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFI 353
Query: 322 ASIMENGSLNIY 333
S ++ +L ++
Sbjct: 354 LSCADDKTLRVW 365
Score = 32.7 bits (73), Expect = 1.7
Identities = 32/140 (22%), Positives = 61/140 (43%), Gaps = 15/140 (10%)
Query: 203 KYQLPAPPESSSILYKVFAVTRD-----GRILAAGGKSNHLHLWCLEARQLFRIIQMPTK 257
K +P PPE ++ VTR ++ + + + +W E R ++
Sbjct: 92 KEWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLK---- 147
Query: 258 VRAIRHLEFLPD-SFDAGSNQVLGVLSQDGIMRFINMQTCKLLFEIGSLDEGISSSAISP 316
H + + D SFD S ++L S D ++ + Q + + + D +SS AI P
Sbjct: 148 ----GHTDSVQDISFDH-SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMP 202
Query: 317 HGRYIASIMENGSLNIYSVQ 336
+G +I S + ++ ++ VQ
Sbjct: 203 NGDHIVSASRDKTIKMWEVQ 222
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 56.6 bits (135), Expect = 1e-07
Identities = 44/184 (23%), Positives = 96/184 (52%), Gaps = 22/184 (11%)
Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEE 749
++ E+IR E R+ + + + K+ +Q E+E W Q +E +R+ EE R+E + ++E+
Sbjct: 357 EQEEKIREQEEKMWRQEEKIREQDEKIQEQ--EEEMWRQ-EEKIREQEEKRQEKMWRQEK 413
Query: 750 KMIQQRQRLAAVKREL-----KVKEMH-----LQDAARRRFLKLQQDQQEME-----LRR 794
KM +Q +++ + E+ K++E+ ++ R K+Q+++++M+ ++R
Sbjct: 414 KMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQR 473
Query: 795 LDDEI-GRKNLTENQEALAKEMRADADAYRRKVDLEEHMF---HKLIEAGETQSQKTQKW 850
+++I ++ T QE L K+ + + EE M+ K+ E E ++ +K
Sbjct: 474 QEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKM 533
Query: 851 KEAE 854
+E E
Sbjct: 534 REQE 537
Score = 46.6 bits (109), Expect = 1e-04
Identities = 43/221 (19%), Positives = 107/221 (48%), Gaps = 30/221 (13%)
Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEE 749
++ E+IR E R+ + + + + K+ +Q E++ W Q++++ + E+ +QE+E
Sbjct: 336 EQEEKIREQEDKMWRQEEKIREQEEKIREQ--EEKMWRQEEKIREQDEK------IQEQE 387
Query: 750 KMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQD----QQEMELRRLDDEIGR-KNL 804
+ + +++ + E + ++M Q+ R +QD +QE E+ R +++I + +
Sbjct: 388 EEMWRQEEKIREQEEKRQEKMWRQEKKMR-----EQDEKIREQEEEMWRQEEKIRELEEM 442
Query: 805 TENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFRLRSAK 864
++QE +E+ K+ EE + E + Q +K Q+ +E ++ +L K
Sbjct: 443 MQDQEEKLREV-------EEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL--LK 493
Query: 865 KASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQD 905
+ + + K + ++E + E ++E + Q +++
Sbjct: 494 QEEKIWEQEEKMWRQEE---KMWEQEEKMQEQEEKMQRQEE 531
Score = 42.4 bits (98), Expect = 0.002
Identities = 58/290 (20%), Positives = 131/290 (45%), Gaps = 35/290 (12%)
Query: 649 LMETTPTDIHPDSMLNVFVALTKGQ-YPVFNQYPKFIVDYQTQER-----ERIRNDELDY 702
L+E T H M LTK + P Y I D + +E+ E++R E +
Sbjct: 175 LLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEK 234
Query: 703 LRERQTVEDMQAKVD-------QQRVEDEAWYQKQELLR-------KAEETRREMLL--Q 746
+ V+D++ K++ QQ+++ EA +EL + EE LL Q
Sbjct: 235 SEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQ 294
Query: 747 EEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQ-DQQEMELRRLDDEIGR---- 801
+EEKM +Q +++ + ++ +E+ +++ + + + ++ +QE ++R +D++ R
Sbjct: 295 QEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEK 354
Query: 802 -----KNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQK-WKEAEG 855
+ + E +E + ++ + + + EE M+ + + E + ++ +K W++
Sbjct: 355 IREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE-- 412
Query: 856 KEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQD 905
K+ R + K + R+ +E+ ++ E + E + Q E++
Sbjct: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Score = 41.2 bits (95), Expect = 0.005
Identities = 23/102 (22%), Positives = 55/102 (53%), Gaps = 13/102 (12%)
Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQ----RVEDEAWYQKQELLRKAE-------- 737
+E E+++ E R+ + +++ + K +Q + E++ W Q++++ R+ E
Sbjct: 459 EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK 518
Query: 738 -ETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARR 778
+ + E + ++EEKM +Q RL + +++ +E+ LQ+ R
Sbjct: 519 MQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEER 560
Score = 35.0 bits (79), Expect = 0.34
Identities = 24/85 (28%), Positives = 47/85 (55%), Gaps = 9/85 (10%)
Query: 688 QTQERERIRNDELDYLRERQTVEDMQAKVDQQRV----EDEAWYQKQELLRKAEETRREM 743
Q QE + R ++L L++ + + + + K+ +Q ++E +++E +++ EE RE
Sbjct: 479 QEQEEKTWRQEKL--LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQ 536
Query: 744 ---LLQEEEKMIQQRQRLAAVKREL 765
L Q+EEKM +Q RL ++ L
Sbjct: 537 EVRLWQQEEKMQEQEVRLQELEERL 561
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 56.6 bits (135), Expect = 1e-07
Identities = 44/184 (23%), Positives = 96/184 (52%), Gaps = 22/184 (11%)
Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEE 749
++ E+IR E R+ + + + K+ +Q E+E W Q +E +R+ EE R+E + ++E+
Sbjct: 357 EQEEKIREQEEKMWRQEEKIREQDEKIQEQ--EEEMWRQ-EEKIREQEEKRQEKMWRQEK 413
Query: 750 KMIQQRQRLAAVKREL-----KVKEMH-----LQDAARRRFLKLQQDQQEME-----LRR 794
KM +Q +++ + E+ K++E+ ++ R K+Q+++++M+ ++R
Sbjct: 414 KMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQR 473
Query: 795 LDDEI-GRKNLTENQEALAKEMRADADAYRRKVDLEEHMF---HKLIEAGETQSQKTQKW 850
+++I ++ T QE L K+ + + EE M+ K+ E E ++ +K
Sbjct: 474 QEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKM 533
Query: 851 KEAE 854
+E E
Sbjct: 534 REQE 537
Score = 46.6 bits (109), Expect = 1e-04
Identities = 43/221 (19%), Positives = 107/221 (48%), Gaps = 30/221 (13%)
Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEE 749
++ E+IR E R+ + + + + K+ +Q E++ W Q++++ + E+ +QE+E
Sbjct: 336 EQEEKIREQEDKMWRQEEKIREQEEKIREQ--EEKMWRQEEKIREQDEK------IQEQE 387
Query: 750 KMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQD----QQEMELRRLDDEIGR-KNL 804
+ + +++ + E + ++M Q+ R +QD +QE E+ R +++I + +
Sbjct: 388 EEMWRQEEKIREQEEKRQEKMWRQEKKMR-----EQDEKIREQEEEMWRQEEKIRELEEM 442
Query: 805 TENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFRLRSAK 864
++QE +E+ K+ EE + E + Q +K Q+ +E ++ +L K
Sbjct: 443 MQDQEEKLREV-------EEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL--LK 493
Query: 865 KASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQD 905
+ + + K + ++E + E ++E + Q +++
Sbjct: 494 QEEKIWEQEEKMWRQEE---KMWEQEEKMQEQEEKMQRQEE 531
Score = 41.2 bits (95), Expect = 0.005
Identities = 39/215 (18%), Positives = 100/215 (46%), Gaps = 15/215 (6%)
Query: 704 RERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLL--QEEEKMIQQRQRLAAV 761
R + + Q +V+ R+ E +L + EE LL Q+EEKM +Q +++
Sbjct: 250 RAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQ 309
Query: 762 KRELKVKEMHLQDAARRRFLKLQQ-DQQEMELRRLDDEIGR---------KNLTENQEAL 811
+ ++ +E+ +++ + + + ++ +QE ++R +D++ R + + E +E +
Sbjct: 310 EEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKM 369
Query: 812 AKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQK-WKEAEGKEFRLRSAKKASALS 870
++ + + + EE M+ + + E + ++ +K W++ K+ R + K
Sbjct: 370 WRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE--KKMREQDEKIREQEE 427
Query: 871 DASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQD 905
+ R+ +E+ ++ E + E + Q E++
Sbjct: 428 EMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Score = 41.2 bits (95), Expect = 0.005
Identities = 23/102 (22%), Positives = 55/102 (53%), Gaps = 13/102 (12%)
Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQ----RVEDEAWYQKQELLRKAE-------- 737
+E E+++ E R+ + +++ + K +Q + E++ W Q++++ R+ E
Sbjct: 459 EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK 518
Query: 738 -ETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARR 778
+ + E + ++EEKM +Q RL + +++ +E+ LQ+ R
Sbjct: 519 MQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEER 560
Score = 35.0 bits (79), Expect = 0.34
Identities = 24/85 (28%), Positives = 47/85 (55%), Gaps = 9/85 (10%)
Query: 688 QTQERERIRNDELDYLRERQTVEDMQAKVDQQRV----EDEAWYQKQELLRKAEETRREM 743
Q QE + R ++L L++ + + + + K+ +Q ++E +++E +++ EE RE
Sbjct: 479 QEQEEKTWRQEKL--LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQ 536
Query: 744 ---LLQEEEKMIQQRQRLAAVKREL 765
L Q+EEKM +Q RL ++ L
Sbjct: 537 EVRLWQQEEKMQEQEVRLQELEERL 561
Score = 30.8 bits (68), Expect = 6.4
Identities = 29/170 (17%), Positives = 74/170 (43%), Gaps = 22/170 (12%)
Query: 742 EMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGR 801
E L +E + + + R ELK K LQ+ + R ++ ++ + ++ ++ L ++ R
Sbjct: 193 EKLTKERDALSLELYRNTITDEELKEKNAELQE--KLRLVESEKSEIQLNVKDLKRKLER 250
Query: 802 KNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGE-----TQSQKTQKWKEAEG- 855
L Q+ +++ +AD +++ +E E Q Q+ + W++ E
Sbjct: 251 AQLLLPQQ----QLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKI 306
Query: 856 KEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQD 905
+E + ++ + + K + ++E H++E + + ++D
Sbjct: 307 QEQEEKMCEQELKIREQEEKMWRQEE----------KMHEQEEKIREQED 346
>gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens]
Length = 841
Score = 56.6 bits (135), Expect = 1e-07
Identities = 73/280 (26%), Positives = 132/280 (47%), Gaps = 37/280 (13%)
Query: 693 ERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEEKMI 752
E+ R EL+ L+ QTVE++QA+V + W++++ L++AEE+ ++ ++EE +
Sbjct: 494 EKARTRELETLQ--QTVEELQAQVHSMDGA-KGWFERR--LKEAEESLQQQQQEQEEALK 548
Query: 753 QQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELR---RLDDEIGRKNLTENQE 809
Q R++ AA ELK KE LQD R L+ Q++++ L+ L E+ K+ + Q
Sbjct: 549 QCREQHAA---ELKGKEEELQDV--RDQLEQAQEERDCHLKTISSLKQEV--KDTVDGQR 601
Query: 810 ALAKEMRADADAYRRKVDLEEHMFHKLIEAGE---TQSQKTQKWKEAEGKEFRLRSAKK- 865
L K+ A +R++ LE KL E + T S+ +E E S +
Sbjct: 602 ILEKKGSAALKDLKRQLHLERKRADKLQERLQDILTNSKSRSGLEELVLSEMNSPSRTQT 661
Query: 866 --ASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSSEMDP 923
+S++S S + L+++ ++AV R + + PR ++L+D +
Sbjct: 662 GDSSSISSFSYREILREKESSAV----------PARSLSSSPQAQPPRPAELSDEEVAE- 710
Query: 924 STQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHRCQ 963
L +R E L +KV++L + A C+
Sbjct: 711 -----LFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLCR 745
Score = 36.6 bits (83), Expect = 0.12
Identities = 44/231 (19%), Positives = 92/231 (39%), Gaps = 24/231 (10%)
Query: 691 ERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEEK 750
E+E + ND + + E Q ++ K R + + Q+ L A ++ E+ Q + +
Sbjct: 248 EKETLFNDSRNKIEELQQRKEADHKAQLARTQ-----KLQQELEAANQSLAELRDQRQGE 302
Query: 751 MIQQRQRLAAVKRELKVKEMHLQD----------AARRRFLKLQQDQ----QEMELRRLD 796
++ L A++ ++ ++ Q+ A R L+Q Q QE+ + R +
Sbjct: 303 RLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQELNMLR-E 361
Query: 797 DEIGRKNLTENQEALAKEMRADADAYRRKVD----LEEHMFHKLIEAGETQSQKTQKWKE 852
G + Q+A +++ D ++ + +L E G+ + Q TQ+ +E
Sbjct: 362 QTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQELQE 421
Query: 853 AEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNE 903
A + ++ A+ K K+E+ A E R++ E
Sbjct: 422 ARKSAEKRKAMLDELAMETLQEKSQHKEELGAVRLRHEKEVLGVRARYERE 472
>gi|219803769 trichoplein [Homo sapiens]
Length = 498
Score = 56.2 bits (134), Expect = 1e-07
Identities = 69/278 (24%), Positives = 124/278 (44%), Gaps = 31/278 (11%)
Query: 690 QERERIRNDELDYLR-ERQTVEDMQAKVDQQRVED----EAWYQKQELLRKAEETRREML 744
QE +R N+ Y R R+ +E M+A+ +++++ED EA Q+ E L K +E L
Sbjct: 182 QENKRYENE---YERARREALERMKAEEERRQLEDKLQAEALLQQMEEL-KLKEVEATKL 237
Query: 745 LQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFL----------KLQQDQQEMEL-R 793
+E+E +++QR L ++ E K E Q A RFL + QQ Q+E+E R
Sbjct: 238 KKEQENLLKQRWELERLEEERKQMEAFRQKAELGRFLRHQYNAQLSRRTQQIQEELEADR 297
Query: 794 RLDDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQ----SQKTQK 849
R+ + K + LA+ + AD K +EE + + E Q + +
Sbjct: 298 RILQALLEKEDESQRLHLARREQVMADVAWMKQAIEEQLQLERAREAELQMLLREEAKEM 357
Query: 850 WKEAEGKEFRLRSAK-KASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSC 908
W++ E + R RSA+ + + R+ ++++I E E +N ++
Sbjct: 358 WEKREAEWARERSARDRLMSEVLTGRQQQIQEKIEQNRRAQEESLKHREQLIRNLEEVRE 417
Query: 909 LPR-----TSQLNDSSEMDPSTQISLNRRAVEWDTTGQ 941
L R + +L + + + Q++ RR W+ Q
Sbjct: 418 LARREKEESEKLKSARKQELEAQVA-ERRLQAWEADQQ 454
Score = 45.1 bits (105), Expect = 3e-04
Identities = 56/229 (24%), Positives = 100/229 (43%), Gaps = 42/229 (18%)
Query: 687 YQTQERERIRNDELDYLRERQTVEDMQAKVDQ----------QRVEDEAWY----QKQEL 732
Y Q R + + + +R+ ++ + K D+ Q + D AW ++Q
Sbjct: 278 YNAQLSRRTQQIQEELEADRRILQALLEKEDESQRLHLARREQVMADVAWMKQAIEEQLQ 337
Query: 733 LRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMEL 792
L +A E +MLL+EE K + ++ R A RE ++ + + R QQ Q+++E
Sbjct: 338 LERAREAELQMLLREEAKEMWEK-REAEWARERSARDRLMSEVLTGR---QQQIQEKIEQ 393
Query: 793 RRLDDEIGRK-------NLTENQEALAKEMRADADAYR--RKVDLEEHMFHKLIEAGETQ 843
R E K NL E +E LA+ + +++ + RK +LE + + ++A E
Sbjct: 394 NRRAQEESLKHREQLIRNLEEVRE-LARREKEESEKLKSARKQELEAQVAERRLQAWEAD 452
Query: 844 SQKTQKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENP 892
Q+ ++ +EA ++ LSDA L+QE E P
Sbjct: 453 QQEEEEEEEA----------RRVEQLSDA----LLQQEAETMAEQGYRP 487
Score = 31.6 bits (70), Expect = 3.8
Identities = 54/237 (22%), Positives = 101/237 (42%), Gaps = 23/237 (9%)
Query: 702 YLRERQTVEDMQAKVDQQRVEDEAWYQKQELL-RKAEETRREMLLQEEEKMIQQRQRLAA 760
Y RE+ E ++ ++ + ++Q+LL R+ EE R M LQ E ++ +Q +L +
Sbjct: 67 YQREKMKEEKRRSLEARREKLRQLMQEEQDLLARELEELRLSMNLQ-ERRIREQHGKLKS 125
Query: 761 VKRELK--VKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIG-RKNLTENQEALAKE--- 814
K E + + E L + ++ KL++ + ++ + + + +K + QEA A++
Sbjct: 126 AKEEQRKLIAEQLLYEHWKKNNPKLREMELDLHQKHVVNSWEMQKEEKKQQEATAEQENK 185
Query: 815 ------MRADADAYRRKVDLEE--HMFHKLIEAGETQSQKTQKWKEAEGKEFRLRSAKKA 866
RA +A R EE + KL Q + K KE E + +
Sbjct: 186 RYENEYERARREALERMKAEEERRQLEDKLQAEALLQQMEELKLKEVEATKLKKEQENLL 245
Query: 867 SALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLP-RTSQLNDSSEMD 922
+ R ++++ A + A E RF Q ++ L RT Q+ + E D
Sbjct: 246 KQRWELERLEEERKQMEAFRQKA------ELGRFLRHQYNAQLSRRTQQIQEELEAD 296
Score = 31.2 bits (69), Expect = 4.9
Identities = 39/163 (23%), Positives = 82/163 (50%), Gaps = 21/163 (12%)
Query: 711 DMQAKVDQQRVEDEAWYQKQELL--RKAEET-----RREMLLQEEEKMIQQRQRLAAVKR 763
+ +A++ QQ ++ +++ ++ ++AE + +R M + EKM ++++R +R
Sbjct: 25 EQEARLRQQWEQNSRYFRMSDICSSKQAEWSSKTSYQRSMHAYQREKMKEEKRRSLEARR 84
Query: 764 E-LKVKEMHLQDAARRRF--LKLQQDQQEMELRRLDDEIGR-KNLTENQ-----EALAKE 814
E L+ QD R L+L + QE RR+ ++ G+ K+ E Q E L E
Sbjct: 85 EKLRQLMQEEQDLLARELEELRLSMNLQE---RRIREQHGKLKSAKEEQRKLIAEQLLYE 141
Query: 815 MRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKE 857
+ R+++L+ H H ++ + E Q ++ +K +EA ++
Sbjct: 142 HWKKNNPKLREMELDLHQKH-VVNSWEMQKEE-KKQQEATAEQ 182
>gi|14150056 trichoplein [Homo sapiens]
Length = 498
Score = 56.2 bits (134), Expect = 1e-07
Identities = 69/278 (24%), Positives = 124/278 (44%), Gaps = 31/278 (11%)
Query: 690 QERERIRNDELDYLR-ERQTVEDMQAKVDQQRVED----EAWYQKQELLRKAEETRREML 744
QE +R N+ Y R R+ +E M+A+ +++++ED EA Q+ E L K +E L
Sbjct: 182 QENKRYENE---YERARREALERMKAEEERRQLEDKLQAEALLQQMEEL-KLKEVEATKL 237
Query: 745 LQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFL----------KLQQDQQEMEL-R 793
+E+E +++QR L ++ E K E Q A RFL + QQ Q+E+E R
Sbjct: 238 KKEQENLLKQRWELERLEEERKQMEAFRQKAELGRFLRHQYNAQLSRRTQQIQEELEADR 297
Query: 794 RLDDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQ----SQKTQK 849
R+ + K + LA+ + AD K +EE + + E Q + +
Sbjct: 298 RILQALLEKEDESQRLHLARREQVMADVAWMKQAIEEQLQLERAREAELQMLLREEAKEM 357
Query: 850 WKEAEGKEFRLRSAK-KASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSC 908
W++ E + R RSA+ + + R+ ++++I E E +N ++
Sbjct: 358 WEKREAEWARERSARDRLMSEVLTGRQQQIQEKIEQNRRAQEESLKHREQLIRNLEEVRE 417
Query: 909 LPR-----TSQLNDSSEMDPSTQISLNRRAVEWDTTGQ 941
L R + +L + + + Q++ RR W+ Q
Sbjct: 418 LARREKEESEKLKSARKQELEAQVA-ERRLQAWEADQQ 454
Score = 45.1 bits (105), Expect = 3e-04
Identities = 56/229 (24%), Positives = 100/229 (43%), Gaps = 42/229 (18%)
Query: 687 YQTQERERIRNDELDYLRERQTVEDMQAKVDQ----------QRVEDEAWY----QKQEL 732
Y Q R + + + +R+ ++ + K D+ Q + D AW ++Q
Sbjct: 278 YNAQLSRRTQQIQEELEADRRILQALLEKEDESQRLHLARREQVMADVAWMKQAIEEQLQ 337
Query: 733 LRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMEL 792
L +A E +MLL+EE K + ++ R A RE ++ + + R QQ Q+++E
Sbjct: 338 LERAREAELQMLLREEAKEMWEK-REAEWARERSARDRLMSEVLTGR---QQQIQEKIEQ 393
Query: 793 RRLDDEIGRK-------NLTENQEALAKEMRADADAYR--RKVDLEEHMFHKLIEAGETQ 843
R E K NL E +E LA+ + +++ + RK +LE + + ++A E
Sbjct: 394 NRRAQEESLKHREQLIRNLEEVRE-LARREKEESEKLKSARKQELEAQVAERRLQAWEAD 452
Query: 844 SQKTQKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENP 892
Q+ ++ +EA ++ LSDA L+QE E P
Sbjct: 453 QQEEEEEEEA----------RRVEQLSDA----LLQQEAETMAEQGYRP 487
Score = 31.6 bits (70), Expect = 3.8
Identities = 54/237 (22%), Positives = 101/237 (42%), Gaps = 23/237 (9%)
Query: 702 YLRERQTVEDMQAKVDQQRVEDEAWYQKQELL-RKAEETRREMLLQEEEKMIQQRQRLAA 760
Y RE+ E ++ ++ + ++Q+LL R+ EE R M LQ E ++ +Q +L +
Sbjct: 67 YQREKMKEEKRRSLEARREKLRQLMQEEQDLLARELEELRLSMNLQ-ERRIREQHGKLKS 125
Query: 761 VKRELK--VKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIG-RKNLTENQEALAKE--- 814
K E + + E L + ++ KL++ + ++ + + + +K + QEA A++
Sbjct: 126 AKEEQRKLIAEQLLYEHWKKNNPKLREMELDLHQKHVVNSWEMQKEEKKQQEATAEQENK 185
Query: 815 ------MRADADAYRRKVDLEE--HMFHKLIEAGETQSQKTQKWKEAEGKEFRLRSAKKA 866
RA +A R EE + KL Q + K KE E + +
Sbjct: 186 RYENEYERARREALERMKAEEERRQLEDKLQAEALLQQMEELKLKEVEATKLKKEQENLL 245
Query: 867 SALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLP-RTSQLNDSSEMD 922
+ R ++++ A + A E RF Q ++ L RT Q+ + E D
Sbjct: 246 KQRWELERLEEERKQMEAFRQKA------ELGRFLRHQYNAQLSRRTQQIQEELEAD 296
Score = 31.2 bits (69), Expect = 4.9
Identities = 39/163 (23%), Positives = 82/163 (50%), Gaps = 21/163 (12%)
Query: 711 DMQAKVDQQRVEDEAWYQKQELL--RKAEET-----RREMLLQEEEKMIQQRQRLAAVKR 763
+ +A++ QQ ++ +++ ++ ++AE + +R M + EKM ++++R +R
Sbjct: 25 EQEARLRQQWEQNSRYFRMSDICSSKQAEWSSKTSYQRSMHAYQREKMKEEKRRSLEARR 84
Query: 764 E-LKVKEMHLQDAARRRF--LKLQQDQQEMELRRLDDEIGR-KNLTENQ-----EALAKE 814
E L+ QD R L+L + QE RR+ ++ G+ K+ E Q E L E
Sbjct: 85 EKLRQLMQEEQDLLARELEELRLSMNLQE---RRIREQHGKLKSAKEEQRKLIAEQLLYE 141
Query: 815 MRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKE 857
+ R+++L+ H H ++ + E Q ++ +K +EA ++
Sbjct: 142 HWKKNNPKLREMELDLHQKH-VVNSWEMQKEE-KKQQEATAEQ 182
>gi|4505257 moesin [Homo sapiens]
Length = 577
Score = 55.5 bits (132), Expect = 2e-07
Identities = 65/250 (26%), Positives = 121/250 (48%), Gaps = 33/250 (13%)
Query: 697 NDELDYLRERQ--TVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQ 754
N EL Y+R R+ T+E Q K Q E++ Q + + + E+ +REM +E+EK+ ++
Sbjct: 287 NHEL-YMRRRKPDTIEVQQMKA--QAREEKHQKQMERAMLENEKKKREMAEKEKEKIERE 343
Query: 755 R----QRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQ--EMELRRLDDEIGRKNLTENQ 808
+ +RL ++ + K + L++ RR L+L+Q+++ + E +L E R+ E +
Sbjct: 344 KEELMERLKQIEEQTKKAQQELEEQTRRA-LELEQERKRAQSEAEKLAKE--RQEAEEAK 400
Query: 809 EALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFRLRSAKKASA 868
EAL ++A D + + L M + A +Q + ++ KE+E E++ +KA
Sbjct: 401 EAL---LQASRDQKKTQEQLALEMAE--LTARISQLEMARQKKESEAVEWQ----QKAQM 451
Query: 869 LSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQD------SSCLPRTSQLNDSSEMD 922
+ + K + + + H P E Q+EQD S+ L + D SE +
Sbjct: 452 VQEDLEKTRAELKTAMSTPHVAEPAENE----QDEQDENGAEASADLRADAMAKDRSEEE 507
Query: 923 PSTQISLNRR 932
+T+ N R
Sbjct: 508 RTTEAEKNER 517
>gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens]
Length = 631
Score = 55.5 bits (132), Expect = 2e-07
Identities = 52/231 (22%), Positives = 108/231 (46%), Gaps = 15/231 (6%)
Query: 105 DYSIKCFDTVTKELVSWMRGHESSVFSISVHASGKYAITTSSD-TAQLWDLDTFQRKRKL 163
D ++K +D + + GH +V+S + H+ G + ++S D T+++WD+++ +R R
Sbjct: 415 DTTVKLWDLCKGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNS-ERCRCT 473
Query: 164 NIRQSVGIQKVFFLPLSNTILSCFKDNSIFAWECDTLFCKYQLPAPPESSSILYKVFAVT 223
+ + + F P SNT+L+ D ++ W+ T C+ L SI +F
Sbjct: 474 LYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYG--HMHSINDAIF--D 529
Query: 224 RDGRILAAGGKSNHLHLWCLEARQLFRIIQMPTKVRAIRHLEFLPDSFDAGSNQVLGVLS 283
G ++A+ LW + R+L I+ + + F DS S +VL S
Sbjct: 530 PRGHMIASCDACGVTKLW--DFRKLLPIVSIDIGPSPGNEVNF--DS----SGRVLAQAS 581
Query: 284 QDGIMRFINMQTCKLLFEIGSLDEGISSSAISPHGRYIASIMENGSLNIYS 334
+G++ +++++ ++ +G +E + S G + S +G++ +S
Sbjct: 582 GNGVIHLLDLKSGEIHKLMGHENEA-HTVVFSHDGEILFSGGSDGTVRTWS 631
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 54.7 bits (130), Expect = 4e-07
Identities = 49/184 (26%), Positives = 89/184 (48%), Gaps = 20/184 (10%)
Query: 688 QTQERERIRNDELDYLR-----ERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRRE 742
Q + R R E+ R ERQ E+ +++++R E+E +++ELLRK EE +
Sbjct: 784 QEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAK 843
Query: 743 MLLQEEE----------KMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMEL 792
+EEE +M ++ RL + E K KE+ +Q R++ L Q+ QQ+ L
Sbjct: 844 WAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ---RQKELMRQRQQQQEAL 900
Query: 793 RRLDDEIGRKNLTENQ--EALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKW 850
RRL + ++ L + + + +++ A + + L KL E E Q ++ Q+
Sbjct: 901 RRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRR 960
Query: 851 KEAE 854
++ E
Sbjct: 961 QQRE 964
Score = 52.0 bits (123), Expect = 3e-06
Identities = 57/177 (32%), Positives = 93/177 (52%), Gaps = 23/177 (12%)
Query: 688 QTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQE 747
Q Q+ E+ + +L+ +ER+ E M+AK E+E +++EL R+ EE R QE
Sbjct: 719 QLQQLEKAKAAKLE--QERREAE-MRAKR-----EEEERKRQEELRRQQEEILRRQ--QE 768
Query: 748 EEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEME-LRRL-----DDEIGR 801
EE+ ++ + LA K+E ++ Q+ A RR + ++ QQ+ E LRRL ++E R
Sbjct: 769 EERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERR 828
Query: 802 KN---LTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQ-SQKTQKWKEAE 854
K L + +E AK R + +A RR LEE+ EA + ++ +K KE E
Sbjct: 829 KQEELLRKQEEEAAKWAREEEEAQRR---LEENRLRMEEEAARLRHEEEERKRKELE 882
Score = 41.2 bits (95), Expect = 0.005
Identities = 48/193 (24%), Positives = 88/193 (45%), Gaps = 25/193 (12%)
Query: 745 LQEEEKM----IQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMEL-RRLDDEI 799
LQ+ EK ++Q +R A ++ + + +E Q+ RR+ ++ + QQE E RR ++E+
Sbjct: 720 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 779
Query: 800 GRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFR 859
R+ QE + R A RR+ + EE + EA ++ ++ +E +E
Sbjct: 780 ARR----KQEEALRRQREQEIALRRQREEEERQQQE--EALRRLEERRREEEERRKQEEL 833
Query: 860 LRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSS 919
LR ++ +A KW A E E EE R + E++++ L +
Sbjct: 834 LRKQEEEAA------KW--------AREEEEAQRRLEENRLRMEEEAARLRHEEEERKRK 879
Query: 920 EMDPSTQISLNRR 932
E++ Q L R+
Sbjct: 880 ELEVQRQKELMRQ 892
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 54.7 bits (130), Expect = 4e-07
Identities = 49/184 (26%), Positives = 89/184 (48%), Gaps = 20/184 (10%)
Query: 688 QTQERERIRNDELDYLR-----ERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRRE 742
Q + R R E+ R ERQ E+ +++++R E+E +++ELLRK EE +
Sbjct: 811 QEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAK 870
Query: 743 MLLQEEE----------KMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMEL 792
+EEE +M ++ RL + E K KE+ +Q R++ L Q+ QQ+ L
Sbjct: 871 WAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ---RQKELMRQRQQQQEAL 927
Query: 793 RRLDDEIGRKNLTENQ--EALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKW 850
RRL + ++ L + + + +++ A + + L KL E E Q ++ Q+
Sbjct: 928 RRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRR 987
Query: 851 KEAE 854
++ E
Sbjct: 988 QQRE 991
Score = 52.0 bits (123), Expect = 3e-06
Identities = 57/177 (32%), Positives = 93/177 (52%), Gaps = 23/177 (12%)
Query: 688 QTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQE 747
Q Q+ E+ + +L+ +ER+ E M+AK E+E +++EL R+ EE R QE
Sbjct: 746 QLQQLEKAKAAKLE--QERREAE-MRAKR-----EEEERKRQEELRRQQEEILRRQ--QE 795
Query: 748 EEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEME-LRRL-----DDEIGR 801
EE+ ++ + LA K+E ++ Q+ A RR + ++ QQ+ E LRRL ++E R
Sbjct: 796 EERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERR 855
Query: 802 KN---LTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQ-SQKTQKWKEAE 854
K L + +E AK R + +A RR LEE+ EA + ++ +K KE E
Sbjct: 856 KQEELLRKQEEEAAKWAREEEEAQRR---LEENRLRMEEEAARLRHEEEERKRKELE 909
Score = 41.2 bits (95), Expect = 0.005
Identities = 48/193 (24%), Positives = 88/193 (45%), Gaps = 25/193 (12%)
Query: 745 LQEEEKM----IQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMEL-RRLDDEI 799
LQ+ EK ++Q +R A ++ + + +E Q+ RR+ ++ + QQE E RR ++E+
Sbjct: 747 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 806
Query: 800 GRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFR 859
R+ QE + R A RR+ + EE + EA ++ ++ +E +E
Sbjct: 807 ARR----KQEEALRRQREQEIALRRQREEEERQQQE--EALRRLEERRREEEERRKQEEL 860
Query: 860 LRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSS 919
LR ++ +A KW A E E EE R + E++++ L +
Sbjct: 861 LRKQEEEAA------KW--------AREEEEAQRRLEENRLRMEEEAARLRHEEEERKRK 906
Query: 920 EMDPSTQISLNRR 932
E++ Q L R+
Sbjct: 907 ELEVQRQKELMRQ 919
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 54.7 bits (130), Expect = 4e-07
Identities = 49/184 (26%), Positives = 89/184 (48%), Gaps = 20/184 (10%)
Query: 688 QTQERERIRNDELDYLR-----ERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRRE 742
Q + R R E+ R ERQ E+ +++++R E+E +++ELLRK EE +
Sbjct: 790 QEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAK 849
Query: 743 MLLQEEE----------KMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMEL 792
+EEE +M ++ RL + E K KE+ +Q R++ L Q+ QQ+ L
Sbjct: 850 WAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ---RQKELMRQRQQQQEAL 906
Query: 793 RRLDDEIGRKNLTENQ--EALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKW 850
RRL + ++ L + + + +++ A + + L KL E E Q ++ Q+
Sbjct: 907 RRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRR 966
Query: 851 KEAE 854
++ E
Sbjct: 967 QQRE 970
Score = 52.0 bits (123), Expect = 3e-06
Identities = 57/177 (32%), Positives = 93/177 (52%), Gaps = 23/177 (12%)
Query: 688 QTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQE 747
Q Q+ E+ + +L+ +ER+ E M+AK E+E +++EL R+ EE R QE
Sbjct: 725 QLQQLEKAKAAKLE--QERREAE-MRAKR-----EEEERKRQEELRRQQEEILRRQ--QE 774
Query: 748 EEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEME-LRRL-----DDEIGR 801
EE+ ++ + LA K+E ++ Q+ A RR + ++ QQ+ E LRRL ++E R
Sbjct: 775 EERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERR 834
Query: 802 KN---LTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQ-SQKTQKWKEAE 854
K L + +E AK R + +A RR LEE+ EA + ++ +K KE E
Sbjct: 835 KQEELLRKQEEEAAKWAREEEEAQRR---LEENRLRMEEEAARLRHEEEERKRKELE 888
Score = 41.2 bits (95), Expect = 0.005
Identities = 48/193 (24%), Positives = 88/193 (45%), Gaps = 25/193 (12%)
Query: 745 LQEEEKM----IQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMEL-RRLDDEI 799
LQ+ EK ++Q +R A ++ + + +E Q+ RR+ ++ + QQE E RR ++E+
Sbjct: 726 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 785
Query: 800 GRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFR 859
R+ QE + R A RR+ + EE + EA ++ ++ +E +E
Sbjct: 786 ARR----KQEEALRRQREQEIALRRQREEEERQQQE--EALRRLEERRREEEERRKQEEL 839
Query: 860 LRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSS 919
LR ++ +A KW A E E EE R + E++++ L +
Sbjct: 840 LRKQEEEAA------KW--------AREEEEAQRRLEENRLRMEEEAARLRHEEEERKRK 885
Query: 920 EMDPSTQISLNRR 932
E++ Q L R+
Sbjct: 886 ELEVQRQKELMRQ 898
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 54.7 bits (130), Expect = 4e-07
Identities = 49/184 (26%), Positives = 89/184 (48%), Gaps = 20/184 (10%)
Query: 688 QTQERERIRNDELDYLR-----ERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRRE 742
Q + R R E+ R ERQ E+ +++++R E+E +++ELLRK EE +
Sbjct: 790 QEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAK 849
Query: 743 MLLQEEE----------KMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMEL 792
+EEE +M ++ RL + E K KE+ +Q R++ L Q+ QQ+ L
Sbjct: 850 WAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ---RQKELMRQRQQQQEAL 906
Query: 793 RRLDDEIGRKNLTENQ--EALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKW 850
RRL + ++ L + + + +++ A + + L KL E E Q ++ Q+
Sbjct: 907 RRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRR 966
Query: 851 KEAE 854
++ E
Sbjct: 967 QQRE 970
Score = 52.0 bits (123), Expect = 3e-06
Identities = 57/177 (32%), Positives = 93/177 (52%), Gaps = 23/177 (12%)
Query: 688 QTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQE 747
Q Q+ E+ + +L+ +ER+ E M+AK E+E +++EL R+ EE R QE
Sbjct: 725 QLQQLEKAKAAKLE--QERREAE-MRAKR-----EEEERKRQEELRRQQEEILRRQ--QE 774
Query: 748 EEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEME-LRRL-----DDEIGR 801
EE+ ++ + LA K+E ++ Q+ A RR + ++ QQ+ E LRRL ++E R
Sbjct: 775 EERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERR 834
Query: 802 KN---LTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQ-SQKTQKWKEAE 854
K L + +E AK R + +A RR LEE+ EA + ++ +K KE E
Sbjct: 835 KQEELLRKQEEEAAKWAREEEEAQRR---LEENRLRMEEEAARLRHEEEERKRKELE 888
Score = 41.2 bits (95), Expect = 0.005
Identities = 48/193 (24%), Positives = 88/193 (45%), Gaps = 25/193 (12%)
Query: 745 LQEEEKM----IQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMEL-RRLDDEI 799
LQ+ EK ++Q +R A ++ + + +E Q+ RR+ ++ + QQE E RR ++E+
Sbjct: 726 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 785
Query: 800 GRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFR 859
R+ QE + R A RR+ + EE + EA ++ ++ +E +E
Sbjct: 786 ARR----KQEEALRRQREQEIALRRQREEEERQQQE--EALRRLEERRREEEERRKQEEL 839
Query: 860 LRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSS 919
LR ++ +A KW A E E EE R + E++++ L +
Sbjct: 840 LRKQEEEAA------KW--------AREEEEAQRRLEENRLRMEEEAARLRHEEEERKRK 885
Query: 920 EMDPSTQISLNRR 932
E++ Q L R+
Sbjct: 886 ELEVQRQKELMRQ 898
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 54.3 bits (129), Expect = 5e-07
Identities = 52/244 (21%), Positives = 111/244 (45%), Gaps = 24/244 (9%)
Query: 673 QYPVFNQYPKFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQEL 732
Q + Q K + + +E+E+ + E R+ + + + + K+ +Q E + W Q +E
Sbjct: 389 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ--EKKMWRQ-EEK 445
Query: 733 LRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKE-MHLQDAARRRFLKLQQDQ---- 787
+ + E+ R E QE+E+M +Q +++ + + KE MH Q+ R++ K+ + +
Sbjct: 446 IHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMH 505
Query: 788 -QEMELRRLDDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQK 846
QE ++R ++++ R QE +E K+ +E M + E Q +K
Sbjct: 506 DQEEKIREQEEKMWR------QEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEK 559
Query: 847 TQKWKEAEGKEFRLRS------AKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRF 900
Q+ ++ +E ++R +K + W +++I E E +EE +
Sbjct: 560 MQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIR---EQEEMMQEQEEKMW 616
Query: 901 QNEQ 904
+ E+
Sbjct: 617 EQEE 620
Score = 47.8 bits (112), Expect = 5e-05
Identities = 38/221 (17%), Positives = 105/221 (47%), Gaps = 19/221 (8%)
Query: 690 QERERIRNDELDYLRERQTVEDMQA--KVDQQRVEDEAWYQKQELLRKAEETRREMLLQE 747
++ E+IR E R+ + + + + + ++++ ++E W Q++++ + E R++ + E
Sbjct: 427 EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHE 486
Query: 748 EEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQ-DQQEMELRRLDDEIGRKNLTE 806
+EK+ +Q +++ + ++ +E +++ + + + ++ +QE ++R +++I
Sbjct: 487 QEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKI------R 540
Query: 807 NQEALAKEMRADADAYRRKVDLEEHM---FHKLIEAGETQSQKTQKWKEAEGKEFRLRSA 863
QE + +E K+ +E M K+ E E ++ +K +E E K +
Sbjct: 541 EQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEK 600
Query: 864 KKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQ 904
+ ++ ++++ E E C +EE + E+
Sbjct: 601 IR-------EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 634
Score = 43.1 bits (100), Expect = 0.001
Identities = 41/188 (21%), Positives = 95/188 (50%), Gaps = 22/188 (11%)
Query: 690 QERERIRNDELDYLRE-----RQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREML 744
++ E+IR E + +RE R+ E M K ++ R ++E ++K+E +R+ EE +
Sbjct: 318 EQEEKIREQE-EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEE-----M 371
Query: 745 LQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQ------QEMELRRLDDE 798
+ E+E+ I++ + + +++ +E Q+ + R + +Q+Q QE ++R +++
Sbjct: 372 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 431
Query: 799 I--GRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGK 856
I K + +E + ++ + + R++ +E M+ + + E + QK K E +
Sbjct: 432 IREQEKKMWRQEEKIHEQEKIREEEKRQE---QEEMWRQEEKIREQEEIWRQKEKMHEQE 488
Query: 857 EFRLRSAK 864
+ R + K
Sbjct: 489 KIRKQEEK 496
Score = 43.1 bits (100), Expect = 0.001
Identities = 38/174 (21%), Positives = 87/174 (50%), Gaps = 19/174 (10%)
Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRV--EDEAWYQKQELLRKAEETRRE--MLL 745
++ E++R E + + + +++ K+ +Q E E Q++E +R+ E+ + + +
Sbjct: 360 EKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 419
Query: 746 QEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEM----ELRRLDDEIGR 801
++EEK+ +Q +++ ++++ +E + + + R + +Q+Q+EM E R +EI R
Sbjct: 420 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 479
Query: 802 -KNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAE 854
K QE + K+ KV +E H E + + Q+ + W++ E
Sbjct: 480 QKEKMHEQEKIRKQ--------EEKVWRQEEKMHDQEE--KIREQEEKMWRQEE 523
Score = 42.0 bits (97), Expect = 0.003
Identities = 32/148 (21%), Positives = 78/148 (52%), Gaps = 14/148 (9%)
Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREM---LLQ 746
++ E+IR E + +RE+ E+M + +++ E E Q+QE +R+ EE RE + +
Sbjct: 527 EQEEKIREQE-EKIREQ---EEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIRE 582
Query: 747 EEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKNLTE 806
++EK+ +Q +++ + +++ +E +Q+ + + +Q+++ E E K +
Sbjct: 583 QKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMW---EQEEKMCEQEEKMQEQEEKMRRQ 639
Query: 807 NQEALAKEMRADADAYRRKVDLEEHMFH 834
++ +E+R +++ ++EH H
Sbjct: 640 EEKMWEQEVR----LRQQEEKMQEHQEH 663
Score = 41.2 bits (95), Expect = 0.005
Identities = 44/213 (20%), Positives = 105/213 (49%), Gaps = 22/213 (10%)
Query: 699 ELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRL 758
E D+L + ++ + AK+ Q E+E W + + + + E + + EEK+ +Q +++
Sbjct: 266 EADHLGKE--LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKI 323
Query: 759 AAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKNLTENQEALAKEMRAD 818
++E K++E Q+ RR ++ +++E ++RR ++ + K E + +EM +
Sbjct: 324 R--EQEEKIRE---QEEKMRRQEEMMWEKEE-KMRRQEEMMWEK---EEKMRRLEEMMWE 374
Query: 819 ADAYRRKVDLEEHMFHKLIEAGETQSQ-----KTQKWKEAEGKEFRL--RSAKKASALSD 871
+ R+++ + H K+ E E + + + +K +E E K +R + ++ + +
Sbjct: 375 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 434
Query: 872 ASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQ 904
+K + ++E H + +EE R + E+
Sbjct: 435 QEKKMWRQEE----KIHEQEKIREEEKRQEQEE 463
Score = 41.2 bits (95), Expect = 0.005
Identities = 20/88 (22%), Positives = 50/88 (56%), Gaps = 4/88 (4%)
Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAE--ETRREMLLQE 747
+++E+IR E + + + + + + +Q E++ W Q++++ + E + + E + ++
Sbjct: 582 EQKEKIREQEEKIWEQEEKIREQEEMMQEQ--EEKMWEQEEKMCEQEEKMQEQEEKMRRQ 639
Query: 748 EEKMIQQRQRLAAVKRELKVKEMHLQDA 775
EEKM +Q RL + +++ + HL+ A
Sbjct: 640 EEKMWEQEVRLRQQEEKMQEHQEHLEAA 667
Score = 36.6 bits (83), Expect = 0.12
Identities = 43/240 (17%), Positives = 111/240 (46%), Gaps = 28/240 (11%)
Query: 680 YPKFIVDYQTQERERIRNDELDYLRERQT-----VEDMQAKVD-------QQRVEDEAWY 727
Y I D + +E+ ++L + ++ V++++ K++ QQ+++ EA +
Sbjct: 210 YRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADH 269
Query: 728 QKQELLRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQD- 786
+EL + + + ++ E + Q+Q ++E K++E + + ++ Q++
Sbjct: 270 LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEK 329
Query: 787 --QQEMELRRLDDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQS 844
+QE ++RR ++ + K E + +EM + + R+ LEE M+ K
Sbjct: 330 IREQEEKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKMRR--LEEMMWEK--------E 376
Query: 845 QKTQKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQ 904
+K ++ +E ++ ++R ++ + R+ +QE A + E ++E + + ++
Sbjct: 377 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 436
Score = 36.2 bits (82), Expect = 0.15
Identities = 25/124 (20%), Positives = 63/124 (50%), Gaps = 8/124 (6%)
Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEET--RREMLLQE 747
QE+E ++ + ++E++ + + K+ +Q +E +++E +R+ EE +E ++E
Sbjct: 547 QEQEEKMGEQEEKMQEQEKMRRQEEKIREQ---EEKIREQKEKIREQEEKIWEQEEKIRE 603
Query: 748 EEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKNLTEN 807
+E+M+Q+++ + E ++ + + ++ E E+R E + + E+
Sbjct: 604 QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE---EKMQEH 660
Query: 808 QEAL 811
QE L
Sbjct: 661 QEHL 664
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 54.3 bits (129), Expect = 5e-07
Identities = 50/246 (20%), Positives = 118/246 (47%), Gaps = 19/246 (7%)
Query: 673 QYPVFNQYPKFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQEL 732
Q + Q K + + +E+E+ + E R+ + + + + K+ +Q E++ W Q +E
Sbjct: 450 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ--EEKMWRQ-EEK 506
Query: 733 LRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKE-MHLQ-DAARRRFLKLQQDQ--- 787
+ + E+ R E QE+E+M +Q +++ + + KE +H Q + R++ K+ + +
Sbjct: 507 IHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKM 566
Query: 788 --QEMELRRLDDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQ 845
QE ++R ++++ R+ E +++R + R + ++ + K+ E E +
Sbjct: 567 HDQEEKIREQEEKVWRQE--EKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCE 624
Query: 846 KTQKWKEAEGK----EFRLRSAKKASALSD---ASRKWFLKQEINAAVEHAENPCHKEEP 898
+ +K +E E K E ++R +K + ++ ++++ E E C +EE
Sbjct: 625 QEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 684
Query: 899 RFQNEQ 904
+ E+
Sbjct: 685 MQEQEE 690
Score = 42.4 bits (98), Expect = 0.002
Identities = 48/223 (21%), Positives = 100/223 (44%), Gaps = 30/223 (13%)
Query: 690 QERERIRNDELDYLRE-----RQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREML 744
++ E+IR E + +RE R+ E M K ++ R ++E ++K+E +R+ EE +
Sbjct: 379 EQEEKIREQE-EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE-----M 432
Query: 745 LQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKNL 804
+ E+E+ I REL+ K MH Q+ R + K Q++++ E + ++ +
Sbjct: 433 MWEKEEKI----------RELEEK-MHEQEKIREQEEKRQEEEKIREQEKRQEQEAK--- 478
Query: 805 TENQEALAKEMRADADAYRRKVDLEEHMFH--KLIEAGETQSQKTQKWKEAEGKEFRLRS 862
QE +E K+ +E H + I E + ++ + W++ E +
Sbjct: 479 MWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 538
Query: 863 AKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQD 905
++ + + K KQE + E H +E + + +++
Sbjct: 539 WRQKEKIHEQEEK-IRKQE--EKMWRQEEKMHDQEEKIREQEE 578
Score = 41.2 bits (95), Expect = 0.005
Identities = 44/214 (20%), Positives = 102/214 (47%), Gaps = 24/214 (11%)
Query: 699 ELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRL 758
E D+L + ++ + AK+ Q E+E W + + + + E + + EEK+ +Q +++
Sbjct: 327 EADHLGKE--LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKI 384
Query: 759 AAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKNLTENQEALAKEMRAD 818
++E K++E Q+ RR ++ +++E ++RR ++ + K E + +EM +
Sbjct: 385 R--EQEEKIRE---QEEKMRRQEEMMWEKEE-KMRRQEEMMWEK---EEKMRRQEEMMWE 435
Query: 819 ADAYRRKVDLEEHMFHKLIEAGETQSQ-----KTQKWKEAEGKEFRLRS---AKKASALS 870
+ R+++ + H K+ E E + + + +K +E E K +R ++
Sbjct: 436 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 495
Query: 871 DASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQ 904
+ W +++I H + +EE R + E+
Sbjct: 496 QEEKMWRQEEKI-----HEQEKIREEEKRQEQEE 524
Score = 40.4 bits (93), Expect = 0.008
Identities = 20/88 (22%), Positives = 49/88 (55%), Gaps = 4/88 (4%)
Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAE--ETRREMLLQE 747
++ E+IR E + + + + + + +Q E++ W Q++++ + E + + E + ++
Sbjct: 638 RQEEKIREQEKKIREQEEKIREQEEMMQEQ--EEKMWEQEEKMCEQEEKMQEQEEKMRRQ 695
Query: 748 EEKMIQQRQRLAAVKRELKVKEMHLQDA 775
EEKM +Q RL + +++ + HL+ A
Sbjct: 696 EEKMWEQEVRLRQQEEKMQEHQEHLEAA 723
Score = 37.0 bits (84), Expect = 0.090
Identities = 26/135 (19%), Positives = 62/135 (45%), Gaps = 16/135 (11%)
Query: 690 QERERIRNDELDYLRERQTVEDMQAKVDQQRV----EDEAWYQKQELLRKAEETRREM-- 743
++ E+IR E + + ++ + K+ +Q ++E +++E +R+ EE RE
Sbjct: 589 EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEK 648
Query: 744 -------LLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLD 796
++E+E+M+Q+++ + E ++ + + ++ E E+R
Sbjct: 649 KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 708
Query: 797 DEIGRKNLTENQEAL 811
E + + E+QE L
Sbjct: 709 QE---EKMQEHQEHL 720
Score = 35.8 bits (81), Expect = 0.20
Identities = 44/242 (18%), Positives = 110/242 (45%), Gaps = 24/242 (9%)
Query: 680 YPKFIVDYQTQERERIRNDELDYLRERQT-----VEDMQAKVD-------QQRVEDEAWY 727
Y I D + +E+ ++L + ++ V++++ K++ QQ+++ EA +
Sbjct: 271 YRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADH 330
Query: 728 QKQELLRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQD- 786
+EL + + + ++ E + Q+Q ++E K++E + + ++ Q++
Sbjct: 331 LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEK 390
Query: 787 --QQEMELRRLDDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGET-- 842
+QE ++RR ++ + K E + M + RR+ ++ K+ E E
Sbjct: 391 IREQEEKMRRQEEMMWEKE--EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 448
Query: 843 QSQKTQKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQN 902
+ +K ++ +E +E ++R +K ++ W +++I E E +EE ++
Sbjct: 449 EQEKIREQEEKRQEEEKIREQEKRQ--EQEAKMWRQEEKIR---EQEEKIREQEEKMWRQ 503
Query: 903 EQ 904
E+
Sbjct: 504 EE 505
Score = 33.5 bits (75), Expect = 0.99
Identities = 28/159 (17%), Positives = 75/159 (47%), Gaps = 23/159 (14%)
Query: 691 ERERIRNDELDYLRERQTVEDMQAKVDQQ----RVEDEAWYQKQELL-----------RK 735
+ E+IR E R+ + + + + K+ +Q R ++E +++E + K
Sbjct: 569 QEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEK 628
Query: 736 AEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRL 795
+E +M ++EEK+ +Q +++ + +++ +E +Q+ + + +Q+++ E
Sbjct: 629 MQEQEEKM-RRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW---EQEEKMCEQEEK 684
Query: 796 DDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFH 834
E K + ++ +E+R +++ ++EH H
Sbjct: 685 MQEQEEKMRRQEEKMWEQEVR----LRQQEEKMQEHQEH 719
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 53.9 bits (128), Expect = 7e-07
Identities = 65/300 (21%), Positives = 135/300 (45%), Gaps = 25/300 (8%)
Query: 678 NQYPKFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQ-KQELLRKA 736
+QY KFI + + E R E ER+ + +++A +++QR EA Q K + R+A
Sbjct: 1331 SQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREA 1390
Query: 737 EETRREM---LLQEEEKMIQQRQRLAAVKREL----KVKEMHLQ------DAARRRFLKL 783
+E ++ M +++ EE + +Q+ +++ EL + E +Q +AA R L++
Sbjct: 1391 KELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRI 1450
Query: 784 QQDQQEMELRRLDDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQ 843
+++ + + L+ E R +AL + +A+A +R+ E + ++
Sbjct: 1451 EEEIRVVRLQLEATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQ----- 1504
Query: 844 SQKTQKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNE 903
++Q+ ++AE E R +A A + R +E+ E AE + E +
Sbjct: 1505 -DESQRKRQAE-VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE--VERA 1560
Query: 904 QDSSCLPRTSQLNDSSEMDPSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHRCQ 963
+ T+Q + +E+ S + S + + + + Q V LR+ RA+ + +
Sbjct: 1561 RQVQVALETAQRSAEAELQ-SKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAE 1619
Score = 52.4 bits (124), Expect = 2e-06
Identities = 55/284 (19%), Positives = 126/284 (44%), Gaps = 16/284 (5%)
Query: 691 ERERIRNDELDYLRERQTVE-------DMQAKVDQQRVEDEAWYQKQELLRKAEETRREM 743
E RIR++ D LR ++ E + A+ +++R E E QK + +R+
Sbjct: 1947 ELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKA 2006
Query: 744 LLQEEEKM---IQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIG 800
L+E E++ +++ +RL + +++ L A ++ L+ ++ +++ + E+
Sbjct: 2007 ALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQEL- 2065
Query: 801 RKNLTENQEALAKEMRADADAYRRKV-DLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFR 859
+ + ++++ ++R +A+A RR + EE EA +++ Q + + + E +
Sbjct: 2066 -QQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2124
Query: 860 LRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSS 919
++ +A A ++ RK ++ A K+ + E+ +T +
Sbjct: 2125 AQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQV 2184
Query: 920 EMDPSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHRCQ 963
E + +T L + E D L ++++ L+ T AR R Q
Sbjct: 2185 EQELTT---LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQ 2225
Score = 50.4 bits (119), Expect = 8e-06
Identities = 60/197 (30%), Positives = 91/197 (46%), Gaps = 37/197 (18%)
Query: 691 ERERIRNDEL---DYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEET----RREM 743
E + +R EL + ++RQ E QQR+ E QEL+R ET ++
Sbjct: 1680 EEQAVRQRELAEQELEKQRQLAEGTA----QQRLAAE-----QELIRLRAETEQGEQQRQ 1730
Query: 744 LLQEEEKMIQQRQRLAAVKRE------LKVK-EMHLQDAARRRFLKLQQDQQEMELRRLD 796
LL+EE +Q+ A KR+ KV+ EM + A++ R + + E +RL+
Sbjct: 1731 LLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLE 1790
Query: 797 DEIGR-KNLTENQ---EALAKEMR-----ADADAYRRKVDLEEHMFHKLIEAGETQSQKT 847
E GR + L E ALA+E + A+ DA R++ + E + KL GE KT
Sbjct: 1791 AEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKT 1850
Query: 848 Q-----KWKEAEGKEFR 859
+ K KEAE + R
Sbjct: 1851 EAEIALKEKEAENERLR 1867
Score = 49.3 bits (116), Expect = 2e-05
Identities = 37/161 (22%), Positives = 85/161 (52%), Gaps = 14/161 (8%)
Query: 686 DYQTQERERIRND----ELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRR 741
+ QT ++E++ + + +L E+ ++ + ++Q++ + E +Q + + KA++ R
Sbjct: 2475 EMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDE--VAKAQQLRE 2532
Query: 742 EMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGR 801
E Q+++ M Q+RQRL A E + ++ ++ RR+ +LQQ +Q+ RR +E+
Sbjct: 2533 EQQRQQQQ-MEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQ---RRQQEEL-- 2586
Query: 802 KNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGET 842
L E + L ++++ + +R + E + + A +T
Sbjct: 2587 --LAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKT 2625
Score = 43.9 bits (102), Expect = 7e-04
Identities = 53/219 (24%), Positives = 100/219 (45%), Gaps = 35/219 (15%)
Query: 690 QERERIRNDELDYLRERQTVEDM-------QAKVDQQRVEDEAWYQKQELLRKAEETRRE 742
+E ER + + LR R E++ QA+ ++Q+ E E +++ + +RE
Sbjct: 1629 RELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRE 1688
Query: 743 MLLQEEEKMIQ-----QRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDD 797
+ QE EK Q +QRLAA + ++ L+ + +Q E + + L++
Sbjct: 1689 LAEQELEKQRQLAEGTAQQRLAAEQELIR--------------LRAETEQGEQQRQLLEE 1734
Query: 798 EIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMF----HKLIEAGETQSQKTQKWKEA 853
E+ R + + A A + R + +A KV E + + E + S+K+++ EA
Sbjct: 1735 ELAR---LQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEA 1791
Query: 854 EGKEFR--LRSAKKASALSDASRKWFLKQEINAAVEHAE 890
E FR A + AL++ +++ E +AA + AE
Sbjct: 1792 EAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAE 1830
Score = 40.4 bits (93), Expect = 0.008
Identities = 49/202 (24%), Positives = 94/202 (46%), Gaps = 41/202 (20%)
Query: 694 RIRNDELDYLRERQTVED----MQAKVDQQR-VEDEAWYQKQ------ELLRKAEETRRE 742
R++ +EL L+ R E+ ++ K + QR +++EA KQ L A+E R
Sbjct: 2234 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARL 2293
Query: 743 MLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRR----FLKLQQDQQEMELRRLDDE 798
L EE+ + QQR A ++ LK K +Q+A R + L+ Q++ + + RRL
Sbjct: 2294 RQLAEED-LAQQR---ALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ-- 2347
Query: 799 IGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEF 858
E++E +A+++ + ++R ++ E + ++ + EAE +
Sbjct: 2348 -------EDKEQMAQQLAEETQGFQRTLEAE-------------RQRQLEMSAEAERLKL 2387
Query: 859 RLRSAKKASALSDASRKWFLKQ 880
R+ +A A ++ + F KQ
Sbjct: 2388 RVAEMSRAQARAEEDAQRFRKQ 2409
Score = 35.4 bits (80), Expect = 0.26
Identities = 46/201 (22%), Positives = 87/201 (43%), Gaps = 13/201 (6%)
Query: 688 QTQERERIR-NDELDYLRERQTVEDMQ---AKVDQQRVE---DEAWYQKQELLRKAEETR 740
+ ER R+R +E+ +R + + Q A+ + Q + +EA QK++ +AE R
Sbjct: 1441 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLR 1500
Query: 741 REMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIG 800
R++ + + K + + + VK E + + L+LQ ++ E LR+ + E
Sbjct: 1501 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERA 1560
Query: 801 RKNLTENQEALAKEMR-ADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFR 859
R + Q AL R A+A+ ++ E E Q +EAE + +
Sbjct: 1561 R----QVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1616
Query: 860 LRSAKKASALSDAS-RKWFLK 879
A++A ++ +W LK
Sbjct: 1617 QAEAERAREEAERELERWQLK 1637
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 53.9 bits (128), Expect = 7e-07
Identities = 65/300 (21%), Positives = 135/300 (45%), Gaps = 25/300 (8%)
Query: 678 NQYPKFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQ-KQELLRKA 736
+QY KFI + + E R E ER+ + +++A +++QR EA Q K + R+A
Sbjct: 1335 SQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREA 1394
Query: 737 EETRREM---LLQEEEKMIQQRQRLAAVKREL----KVKEMHLQ------DAARRRFLKL 783
+E ++ M +++ EE + +Q+ +++ EL + E +Q +AA R L++
Sbjct: 1395 KELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRI 1454
Query: 784 QQDQQEMELRRLDDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQ 843
+++ + + L+ E R +AL + +A+A +R+ E + ++
Sbjct: 1455 EEEIRVVRLQLEATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQ----- 1508
Query: 844 SQKTQKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNE 903
++Q+ ++AE E R +A A + R +E+ E AE + E +
Sbjct: 1509 -DESQRKRQAE-VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE--VERA 1564
Query: 904 QDSSCLPRTSQLNDSSEMDPSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHRCQ 963
+ T+Q + +E+ S + S + + + + Q V LR+ RA+ + +
Sbjct: 1565 RQVQVALETAQRSAEAELQ-SKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAE 1623
Score = 52.4 bits (124), Expect = 2e-06
Identities = 55/284 (19%), Positives = 126/284 (44%), Gaps = 16/284 (5%)
Query: 691 ERERIRNDELDYLRERQTVE-------DMQAKVDQQRVEDEAWYQKQELLRKAEETRREM 743
E RIR++ D LR ++ E + A+ +++R E E QK + +R+
Sbjct: 1951 ELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKA 2010
Query: 744 LLQEEEKM---IQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIG 800
L+E E++ +++ +RL + +++ L A ++ L+ ++ +++ + E+
Sbjct: 2011 ALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQEL- 2069
Query: 801 RKNLTENQEALAKEMRADADAYRRKV-DLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFR 859
+ + ++++ ++R +A+A RR + EE EA +++ Q + + + E +
Sbjct: 2070 -QQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2128
Query: 860 LRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSS 919
++ +A A ++ RK ++ A K+ + E+ +T +
Sbjct: 2129 AQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQV 2188
Query: 920 EMDPSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHRCQ 963
E + +T L + E D L ++++ L+ T AR R Q
Sbjct: 2189 EQELTT---LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQ 2229
Score = 50.4 bits (119), Expect = 8e-06
Identities = 60/197 (30%), Positives = 91/197 (46%), Gaps = 37/197 (18%)
Query: 691 ERERIRNDEL---DYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEET----RREM 743
E + +R EL + ++RQ E QQR+ E QEL+R ET ++
Sbjct: 1684 EEQAVRQRELAEQELEKQRQLAEGTA----QQRLAAE-----QELIRLRAETEQGEQQRQ 1734
Query: 744 LLQEEEKMIQQRQRLAAVKRE------LKVK-EMHLQDAARRRFLKLQQDQQEMELRRLD 796
LL+EE +Q+ A KR+ KV+ EM + A++ R + + E +RL+
Sbjct: 1735 LLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLE 1794
Query: 797 DEIGR-KNLTENQ---EALAKEMR-----ADADAYRRKVDLEEHMFHKLIEAGETQSQKT 847
E GR + L E ALA+E + A+ DA R++ + E + KL GE KT
Sbjct: 1795 AEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKT 1854
Query: 848 Q-----KWKEAEGKEFR 859
+ K KEAE + R
Sbjct: 1855 EAEIALKEKEAENERLR 1871
Score = 49.3 bits (116), Expect = 2e-05
Identities = 37/161 (22%), Positives = 85/161 (52%), Gaps = 14/161 (8%)
Query: 686 DYQTQERERIRND----ELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRR 741
+ QT ++E++ + + +L E+ ++ + ++Q++ + E +Q + + KA++ R
Sbjct: 2479 EMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDE--VAKAQQLRE 2536
Query: 742 EMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGR 801
E Q+++ M Q+RQRL A E + ++ ++ RR+ +LQQ +Q+ RR +E+
Sbjct: 2537 EQQRQQQQ-MEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQ---RRQQEEL-- 2590
Query: 802 KNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGET 842
L E + L ++++ + +R + E + + A +T
Sbjct: 2591 --LAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKT 2629
Score = 43.9 bits (102), Expect = 7e-04
Identities = 53/219 (24%), Positives = 100/219 (45%), Gaps = 35/219 (15%)
Query: 690 QERERIRNDELDYLRERQTVEDM-------QAKVDQQRVEDEAWYQKQELLRKAEETRRE 742
+E ER + + LR R E++ QA+ ++Q+ E E +++ + +RE
Sbjct: 1633 RELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRE 1692
Query: 743 MLLQEEEKMIQ-----QRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDD 797
+ QE EK Q +QRLAA + ++ L+ + +Q E + + L++
Sbjct: 1693 LAEQELEKQRQLAEGTAQQRLAAEQELIR--------------LRAETEQGEQQRQLLEE 1738
Query: 798 EIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMF----HKLIEAGETQSQKTQKWKEA 853
E+ R + + A A + R + +A KV E + + E + S+K+++ EA
Sbjct: 1739 ELAR---LQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEA 1795
Query: 854 EGKEFR--LRSAKKASALSDASRKWFLKQEINAAVEHAE 890
E FR A + AL++ +++ E +AA + AE
Sbjct: 1796 EAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAE 1834
Score = 40.4 bits (93), Expect = 0.008
Identities = 49/202 (24%), Positives = 94/202 (46%), Gaps = 41/202 (20%)
Query: 694 RIRNDELDYLRERQTVED----MQAKVDQQR-VEDEAWYQKQ------ELLRKAEETRRE 742
R++ +EL L+ R E+ ++ K + QR +++EA KQ L A+E R
Sbjct: 2238 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARL 2297
Query: 743 MLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRR----FLKLQQDQQEMELRRLDDE 798
L EE+ + QQR A ++ LK K +Q+A R + L+ Q++ + + RRL
Sbjct: 2298 RQLAEED-LAQQR---ALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ-- 2351
Query: 799 IGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEF 858
E++E +A+++ + ++R ++ E + ++ + EAE +
Sbjct: 2352 -------EDKEQMAQQLAEETQGFQRTLEAE-------------RQRQLEMSAEAERLKL 2391
Query: 859 RLRSAKKASALSDASRKWFLKQ 880
R+ +A A ++ + F KQ
Sbjct: 2392 RVAEMSRAQARAEEDAQRFRKQ 2413
Score = 35.4 bits (80), Expect = 0.26
Identities = 46/201 (22%), Positives = 87/201 (43%), Gaps = 13/201 (6%)
Query: 688 QTQERERIR-NDELDYLRERQTVEDMQ---AKVDQQRVE---DEAWYQKQELLRKAEETR 740
+ ER R+R +E+ +R + + Q A+ + Q + +EA QK++ +AE R
Sbjct: 1445 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLR 1504
Query: 741 REMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIG 800
R++ + + K + + + VK E + + L+LQ ++ E LR+ + E
Sbjct: 1505 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERA 1564
Query: 801 RKNLTENQEALAKEMR-ADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFR 859
R + Q AL R A+A+ ++ E E Q +EAE + +
Sbjct: 1565 R----QVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1620
Query: 860 LRSAKKASALSDAS-RKWFLK 879
A++A ++ +W LK
Sbjct: 1621 QAEAERAREEAERELERWQLK 1641
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 53.9 bits (128), Expect = 7e-07
Identities = 65/300 (21%), Positives = 135/300 (45%), Gaps = 25/300 (8%)
Query: 678 NQYPKFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQ-KQELLRKA 736
+QY KFI + + E R E ER+ + +++A +++QR EA Q K + R+A
Sbjct: 1331 SQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREA 1390
Query: 737 EETRREM---LLQEEEKMIQQRQRLAAVKREL----KVKEMHLQ------DAARRRFLKL 783
+E ++ M +++ EE + +Q+ +++ EL + E +Q +AA R L++
Sbjct: 1391 KELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRI 1450
Query: 784 QQDQQEMELRRLDDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQ 843
+++ + + L+ E R +AL + +A+A +R+ E + ++
Sbjct: 1451 EEEIRVVRLQLEATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQ----- 1504
Query: 844 SQKTQKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNE 903
++Q+ ++AE E R +A A + R +E+ E AE + E +
Sbjct: 1505 -DESQRKRQAE-VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE--VERA 1560
Query: 904 QDSSCLPRTSQLNDSSEMDPSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHRCQ 963
+ T+Q + +E+ S + S + + + + Q V LR+ RA+ + +
Sbjct: 1561 RQVQVALETAQRSAEAELQ-SKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAE 1619
Score = 52.4 bits (124), Expect = 2e-06
Identities = 55/284 (19%), Positives = 126/284 (44%), Gaps = 16/284 (5%)
Query: 691 ERERIRNDELDYLRERQTVE-------DMQAKVDQQRVEDEAWYQKQELLRKAEETRREM 743
E RIR++ D LR ++ E + A+ +++R E E QK + +R+
Sbjct: 1947 ELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKA 2006
Query: 744 LLQEEEKM---IQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIG 800
L+E E++ +++ +RL + +++ L A ++ L+ ++ +++ + E+
Sbjct: 2007 ALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQEL- 2065
Query: 801 RKNLTENQEALAKEMRADADAYRRKV-DLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFR 859
+ + ++++ ++R +A+A RR + EE EA +++ Q + + + E +
Sbjct: 2066 -QQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2124
Query: 860 LRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSS 919
++ +A A ++ RK ++ A K+ + E+ +T +
Sbjct: 2125 AQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQV 2184
Query: 920 EMDPSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHRCQ 963
E + +T L + E D L ++++ L+ T AR R Q
Sbjct: 2185 EQELTT---LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQ 2225
Score = 50.4 bits (119), Expect = 8e-06
Identities = 60/197 (30%), Positives = 91/197 (46%), Gaps = 37/197 (18%)
Query: 691 ERERIRNDEL---DYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEET----RREM 743
E + +R EL + ++RQ E QQR+ E QEL+R ET ++
Sbjct: 1680 EEQAVRQRELAEQELEKQRQLAEGTA----QQRLAAE-----QELIRLRAETEQGEQQRQ 1730
Query: 744 LLQEEEKMIQQRQRLAAVKRE------LKVK-EMHLQDAARRRFLKLQQDQQEMELRRLD 796
LL+EE +Q+ A KR+ KV+ EM + A++ R + + E +RL+
Sbjct: 1731 LLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLE 1790
Query: 797 DEIGR-KNLTENQ---EALAKEMR-----ADADAYRRKVDLEEHMFHKLIEAGETQSQKT 847
E GR + L E ALA+E + A+ DA R++ + E + KL GE KT
Sbjct: 1791 AEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKT 1850
Query: 848 Q-----KWKEAEGKEFR 859
+ K KEAE + R
Sbjct: 1851 EAEIALKEKEAENERLR 1867
Score = 49.3 bits (116), Expect = 2e-05
Identities = 37/161 (22%), Positives = 85/161 (52%), Gaps = 14/161 (8%)
Query: 686 DYQTQERERIRND----ELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRR 741
+ QT ++E++ + + +L E+ ++ + ++Q++ + E +Q + + KA++ R
Sbjct: 2475 EMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDE--VAKAQQLRE 2532
Query: 742 EMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGR 801
E Q+++ M Q+RQRL A E + ++ ++ RR+ +LQQ +Q+ RR +E+
Sbjct: 2533 EQQRQQQQ-MEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQ---RRQQEEL-- 2586
Query: 802 KNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGET 842
L E + L ++++ + +R + E + + A +T
Sbjct: 2587 --LAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKT 2625
Score = 43.9 bits (102), Expect = 7e-04
Identities = 53/219 (24%), Positives = 100/219 (45%), Gaps = 35/219 (15%)
Query: 690 QERERIRNDELDYLRERQTVEDM-------QAKVDQQRVEDEAWYQKQELLRKAEETRRE 742
+E ER + + LR R E++ QA+ ++Q+ E E +++ + +RE
Sbjct: 1629 RELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRE 1688
Query: 743 MLLQEEEKMIQ-----QRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDD 797
+ QE EK Q +QRLAA + ++ L+ + +Q E + + L++
Sbjct: 1689 LAEQELEKQRQLAEGTAQQRLAAEQELIR--------------LRAETEQGEQQRQLLEE 1734
Query: 798 EIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMF----HKLIEAGETQSQKTQKWKEA 853
E+ R + + A A + R + +A KV E + + E + S+K+++ EA
Sbjct: 1735 ELAR---LQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEA 1791
Query: 854 EGKEFR--LRSAKKASALSDASRKWFLKQEINAAVEHAE 890
E FR A + AL++ +++ E +AA + AE
Sbjct: 1792 EAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAE 1830
Score = 40.4 bits (93), Expect = 0.008
Identities = 49/202 (24%), Positives = 94/202 (46%), Gaps = 41/202 (20%)
Query: 694 RIRNDELDYLRERQTVED----MQAKVDQQR-VEDEAWYQKQ------ELLRKAEETRRE 742
R++ +EL L+ R E+ ++ K + QR +++EA KQ L A+E R
Sbjct: 2234 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARL 2293
Query: 743 MLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRR----FLKLQQDQQEMELRRLDDE 798
L EE+ + QQR A ++ LK K +Q+A R + L+ Q++ + + RRL
Sbjct: 2294 RQLAEED-LAQQR---ALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ-- 2347
Query: 799 IGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEF 858
E++E +A+++ + ++R ++ E + ++ + EAE +
Sbjct: 2348 -------EDKEQMAQQLAEETQGFQRTLEAE-------------RQRQLEMSAEAERLKL 2387
Query: 859 RLRSAKKASALSDASRKWFLKQ 880
R+ +A A ++ + F KQ
Sbjct: 2388 RVAEMSRAQARAEEDAQRFRKQ 2409
Score = 35.4 bits (80), Expect = 0.26
Identities = 46/201 (22%), Positives = 87/201 (43%), Gaps = 13/201 (6%)
Query: 688 QTQERERIR-NDELDYLRERQTVEDMQ---AKVDQQRVE---DEAWYQKQELLRKAEETR 740
+ ER R+R +E+ +R + + Q A+ + Q + +EA QK++ +AE R
Sbjct: 1441 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLR 1500
Query: 741 REMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIG 800
R++ + + K + + + VK E + + L+LQ ++ E LR+ + E
Sbjct: 1501 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERA 1560
Query: 801 RKNLTENQEALAKEMR-ADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFR 859
R + Q AL R A+A+ ++ E E Q +EAE + +
Sbjct: 1561 R----QVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1616
Query: 860 LRSAKKASALSDAS-RKWFLK 879
A++A ++ +W LK
Sbjct: 1617 QAEAERAREEAERELERWQLK 1637
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 53.9 bits (128), Expect = 7e-07
Identities = 65/300 (21%), Positives = 135/300 (45%), Gaps = 25/300 (8%)
Query: 678 NQYPKFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQ-KQELLRKA 736
+QY KFI + + E R E ER+ + +++A +++QR EA Q K + R+A
Sbjct: 1299 SQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREA 1358
Query: 737 EETRREM---LLQEEEKMIQQRQRLAAVKREL----KVKEMHLQ------DAARRRFLKL 783
+E ++ M +++ EE + +Q+ +++ EL + E +Q +AA R L++
Sbjct: 1359 KELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRI 1418
Query: 784 QQDQQEMELRRLDDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQ 843
+++ + + L+ E R +AL + +A+A +R+ E + ++
Sbjct: 1419 EEEIRVVRLQLEATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQ----- 1472
Query: 844 SQKTQKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNE 903
++Q+ ++AE E R +A A + R +E+ E AE + E +
Sbjct: 1473 -DESQRKRQAE-VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE--VERA 1528
Query: 904 QDSSCLPRTSQLNDSSEMDPSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHRCQ 963
+ T+Q + +E+ S + S + + + + Q V LR+ RA+ + +
Sbjct: 1529 RQVQVALETAQRSAEAELQ-SKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAE 1587
Score = 52.4 bits (124), Expect = 2e-06
Identities = 55/284 (19%), Positives = 126/284 (44%), Gaps = 16/284 (5%)
Query: 691 ERERIRNDELDYLRERQTVE-------DMQAKVDQQRVEDEAWYQKQELLRKAEETRREM 743
E RIR++ D LR ++ E + A+ +++R E E QK + +R+
Sbjct: 1915 ELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKA 1974
Query: 744 LLQEEEKM---IQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIG 800
L+E E++ +++ +RL + +++ L A ++ L+ ++ +++ + E+
Sbjct: 1975 ALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQEL- 2033
Query: 801 RKNLTENQEALAKEMRADADAYRRKV-DLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFR 859
+ + ++++ ++R +A+A RR + EE EA +++ Q + + + E +
Sbjct: 2034 -QQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2092
Query: 860 LRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSS 919
++ +A A ++ RK ++ A K+ + E+ +T +
Sbjct: 2093 AQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQV 2152
Query: 920 EMDPSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHRCQ 963
E + +T L + E D L ++++ L+ T AR R Q
Sbjct: 2153 EQELTT---LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQ 2193
Score = 50.4 bits (119), Expect = 8e-06
Identities = 60/197 (30%), Positives = 91/197 (46%), Gaps = 37/197 (18%)
Query: 691 ERERIRNDEL---DYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEET----RREM 743
E + +R EL + ++RQ E QQR+ E QEL+R ET ++
Sbjct: 1648 EEQAVRQRELAEQELEKQRQLAEGTA----QQRLAAE-----QELIRLRAETEQGEQQRQ 1698
Query: 744 LLQEEEKMIQQRQRLAAVKRE------LKVK-EMHLQDAARRRFLKLQQDQQEMELRRLD 796
LL+EE +Q+ A KR+ KV+ EM + A++ R + + E +RL+
Sbjct: 1699 LLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLE 1758
Query: 797 DEIGR-KNLTENQ---EALAKEMR-----ADADAYRRKVDLEEHMFHKLIEAGETQSQKT 847
E GR + L E ALA+E + A+ DA R++ + E + KL GE KT
Sbjct: 1759 AEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKT 1818
Query: 848 Q-----KWKEAEGKEFR 859
+ K KEAE + R
Sbjct: 1819 EAEIALKEKEAENERLR 1835
Score = 49.3 bits (116), Expect = 2e-05
Identities = 37/161 (22%), Positives = 85/161 (52%), Gaps = 14/161 (8%)
Query: 686 DYQTQERERIRND----ELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRR 741
+ QT ++E++ + + +L E+ ++ + ++Q++ + E +Q + + KA++ R
Sbjct: 2443 EMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDE--VAKAQQLRE 2500
Query: 742 EMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGR 801
E Q+++ M Q+RQRL A E + ++ ++ RR+ +LQQ +Q+ RR +E+
Sbjct: 2501 EQQRQQQQ-MEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQ---RRQQEEL-- 2554
Query: 802 KNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGET 842
L E + L ++++ + +R + E + + A +T
Sbjct: 2555 --LAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKT 2593
Score = 43.9 bits (102), Expect = 7e-04
Identities = 53/219 (24%), Positives = 100/219 (45%), Gaps = 35/219 (15%)
Query: 690 QERERIRNDELDYLRERQTVEDM-------QAKVDQQRVEDEAWYQKQELLRKAEETRRE 742
+E ER + + LR R E++ QA+ ++Q+ E E +++ + +RE
Sbjct: 1597 RELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRE 1656
Query: 743 MLLQEEEKMIQ-----QRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDD 797
+ QE EK Q +QRLAA + ++ L+ + +Q E + + L++
Sbjct: 1657 LAEQELEKQRQLAEGTAQQRLAAEQELIR--------------LRAETEQGEQQRQLLEE 1702
Query: 798 EIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMF----HKLIEAGETQSQKTQKWKEA 853
E+ R + + A A + R + +A KV E + + E + S+K+++ EA
Sbjct: 1703 ELAR---LQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEA 1759
Query: 854 EGKEFR--LRSAKKASALSDASRKWFLKQEINAAVEHAE 890
E FR A + AL++ +++ E +AA + AE
Sbjct: 1760 EAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAE 1798
Score = 40.4 bits (93), Expect = 0.008
Identities = 49/202 (24%), Positives = 94/202 (46%), Gaps = 41/202 (20%)
Query: 694 RIRNDELDYLRERQTVED----MQAKVDQQR-VEDEAWYQKQ------ELLRKAEETRRE 742
R++ +EL L+ R E+ ++ K + QR +++EA KQ L A+E R
Sbjct: 2202 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARL 2261
Query: 743 MLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRR----FLKLQQDQQEMELRRLDDE 798
L EE+ + QQR A ++ LK K +Q+A R + L+ Q++ + + RRL
Sbjct: 2262 RQLAEED-LAQQR---ALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ-- 2315
Query: 799 IGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEF 858
E++E +A+++ + ++R ++ E + ++ + EAE +
Sbjct: 2316 -------EDKEQMAQQLAEETQGFQRTLEAE-------------RQRQLEMSAEAERLKL 2355
Query: 859 RLRSAKKASALSDASRKWFLKQ 880
R+ +A A ++ + F KQ
Sbjct: 2356 RVAEMSRAQARAEEDAQRFRKQ 2377
Score = 35.4 bits (80), Expect = 0.26
Identities = 46/201 (22%), Positives = 87/201 (43%), Gaps = 13/201 (6%)
Query: 688 QTQERERIR-NDELDYLRERQTVEDMQ---AKVDQQRVE---DEAWYQKQELLRKAEETR 740
+ ER R+R +E+ +R + + Q A+ + Q + +EA QK++ +AE R
Sbjct: 1409 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLR 1468
Query: 741 REMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIG 800
R++ + + K + + + VK E + + L+LQ ++ E LR+ + E
Sbjct: 1469 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERA 1528
Query: 801 RKNLTENQEALAKEMR-ADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFR 859
R + Q AL R A+A+ ++ E E Q +EAE + +
Sbjct: 1529 R----QVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1584
Query: 860 LRSAKKASALSDAS-RKWFLK 879
A++A ++ +W LK
Sbjct: 1585 QAEAERAREEAERELERWQLK 1605
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 53.9 bits (128), Expect = 7e-07
Identities = 65/300 (21%), Positives = 135/300 (45%), Gaps = 25/300 (8%)
Query: 678 NQYPKFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQ-KQELLRKA 736
+QY KFI + + E R E ER+ + +++A +++QR EA Q K + R+A
Sbjct: 1468 SQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREA 1527
Query: 737 EETRREM---LLQEEEKMIQQRQRLAAVKREL----KVKEMHLQ------DAARRRFLKL 783
+E ++ M +++ EE + +Q+ +++ EL + E +Q +AA R L++
Sbjct: 1528 KELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRI 1587
Query: 784 QQDQQEMELRRLDDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQ 843
+++ + + L+ E R +AL + +A+A +R+ E + ++
Sbjct: 1588 EEEIRVVRLQLEATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQ----- 1641
Query: 844 SQKTQKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNE 903
++Q+ ++AE E R +A A + R +E+ E AE + E +
Sbjct: 1642 -DESQRKRQAE-VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE--VERA 1697
Query: 904 QDSSCLPRTSQLNDSSEMDPSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHRCQ 963
+ T+Q + +E+ S + S + + + + Q V LR+ RA+ + +
Sbjct: 1698 RQVQVALETAQRSAEAELQ-SKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAE 1756
Score = 52.4 bits (124), Expect = 2e-06
Identities = 55/284 (19%), Positives = 126/284 (44%), Gaps = 16/284 (5%)
Query: 691 ERERIRNDELDYLRERQTVE-------DMQAKVDQQRVEDEAWYQKQELLRKAEETRREM 743
E RIR++ D LR ++ E + A+ +++R E E QK + +R+
Sbjct: 2084 ELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKA 2143
Query: 744 LLQEEEKM---IQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIG 800
L+E E++ +++ +RL + +++ L A ++ L+ ++ +++ + E+
Sbjct: 2144 ALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQEL- 2202
Query: 801 RKNLTENQEALAKEMRADADAYRRKV-DLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFR 859
+ + ++++ ++R +A+A RR + EE EA +++ Q + + + E +
Sbjct: 2203 -QQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2261
Query: 860 LRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSS 919
++ +A A ++ RK ++ A K+ + E+ +T +
Sbjct: 2262 AQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQV 2321
Query: 920 EMDPSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHRCQ 963
E + +T L + E D L ++++ L+ T AR R Q
Sbjct: 2322 EQELTT---LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQ 2362
Score = 50.4 bits (119), Expect = 8e-06
Identities = 60/197 (30%), Positives = 91/197 (46%), Gaps = 37/197 (18%)
Query: 691 ERERIRNDEL---DYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEET----RREM 743
E + +R EL + ++RQ E QQR+ E QEL+R ET ++
Sbjct: 1817 EEQAVRQRELAEQELEKQRQLAEGTA----QQRLAAE-----QELIRLRAETEQGEQQRQ 1867
Query: 744 LLQEEEKMIQQRQRLAAVKRE------LKVK-EMHLQDAARRRFLKLQQDQQEMELRRLD 796
LL+EE +Q+ A KR+ KV+ EM + A++ R + + E +RL+
Sbjct: 1868 LLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLE 1927
Query: 797 DEIGR-KNLTENQ---EALAKEMR-----ADADAYRRKVDLEEHMFHKLIEAGETQSQKT 847
E GR + L E ALA+E + A+ DA R++ + E + KL GE KT
Sbjct: 1928 AEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKT 1987
Query: 848 Q-----KWKEAEGKEFR 859
+ K KEAE + R
Sbjct: 1988 EAEIALKEKEAENERLR 2004
Score = 49.3 bits (116), Expect = 2e-05
Identities = 37/161 (22%), Positives = 85/161 (52%), Gaps = 14/161 (8%)
Query: 686 DYQTQERERIRND----ELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRR 741
+ QT ++E++ + + +L E+ ++ + ++Q++ + E +Q + + KA++ R
Sbjct: 2612 EMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDE--VAKAQQLRE 2669
Query: 742 EMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGR 801
E Q+++ M Q+RQRL A E + ++ ++ RR+ +LQQ +Q+ RR +E+
Sbjct: 2670 EQQRQQQQ-MEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQ---RRQQEEL-- 2723
Query: 802 KNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGET 842
L E + L ++++ + +R + E + + A +T
Sbjct: 2724 --LAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKT 2762
Score = 43.9 bits (102), Expect = 7e-04
Identities = 53/219 (24%), Positives = 100/219 (45%), Gaps = 35/219 (15%)
Query: 690 QERERIRNDELDYLRERQTVEDM-------QAKVDQQRVEDEAWYQKQELLRKAEETRRE 742
+E ER + + LR R E++ QA+ ++Q+ E E +++ + +RE
Sbjct: 1766 RELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRE 1825
Query: 743 MLLQEEEKMIQ-----QRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDD 797
+ QE EK Q +QRLAA + ++ L+ + +Q E + + L++
Sbjct: 1826 LAEQELEKQRQLAEGTAQQRLAAEQELIR--------------LRAETEQGEQQRQLLEE 1871
Query: 798 EIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMF----HKLIEAGETQSQKTQKWKEA 853
E+ R + + A A + R + +A KV E + + E + S+K+++ EA
Sbjct: 1872 ELAR---LQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEA 1928
Query: 854 EGKEFR--LRSAKKASALSDASRKWFLKQEINAAVEHAE 890
E FR A + AL++ +++ E +AA + AE
Sbjct: 1929 EAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAE 1967
Score = 40.4 bits (93), Expect = 0.008
Identities = 49/202 (24%), Positives = 94/202 (46%), Gaps = 41/202 (20%)
Query: 694 RIRNDELDYLRERQTVED----MQAKVDQQR-VEDEAWYQKQ------ELLRKAEETRRE 742
R++ +EL L+ R E+ ++ K + QR +++EA KQ L A+E R
Sbjct: 2371 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARL 2430
Query: 743 MLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRR----FLKLQQDQQEMELRRLDDE 798
L EE+ + QQR A ++ LK K +Q+A R + L+ Q++ + + RRL
Sbjct: 2431 RQLAEED-LAQQR---ALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ-- 2484
Query: 799 IGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEF 858
E++E +A+++ + ++R ++ E + ++ + EAE +
Sbjct: 2485 -------EDKEQMAQQLAEETQGFQRTLEAE-------------RQRQLEMSAEAERLKL 2524
Query: 859 RLRSAKKASALSDASRKWFLKQ 880
R+ +A A ++ + F KQ
Sbjct: 2525 RVAEMSRAQARAEEDAQRFRKQ 2546
Score = 35.4 bits (80), Expect = 0.26
Identities = 46/201 (22%), Positives = 87/201 (43%), Gaps = 13/201 (6%)
Query: 688 QTQERERIR-NDELDYLRERQTVEDMQ---AKVDQQRVE---DEAWYQKQELLRKAEETR 740
+ ER R+R +E+ +R + + Q A+ + Q + +EA QK++ +AE R
Sbjct: 1578 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLR 1637
Query: 741 REMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIG 800
R++ + + K + + + VK E + + L+LQ ++ E LR+ + E
Sbjct: 1638 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERA 1697
Query: 801 RKNLTENQEALAKEMR-ADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFR 859
R + Q AL R A+A+ ++ E E Q +EAE + +
Sbjct: 1698 R----QVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1753
Query: 860 LRSAKKASALSDAS-RKWFLK 879
A++A ++ +W LK
Sbjct: 1754 QAEAERAREEAERELERWQLK 1774
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 53.9 bits (128), Expect = 7e-07
Identities = 65/300 (21%), Positives = 135/300 (45%), Gaps = 25/300 (8%)
Query: 678 NQYPKFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQ-KQELLRKA 736
+QY KFI + + E R E ER+ + +++A +++QR EA Q K + R+A
Sbjct: 1309 SQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREA 1368
Query: 737 EETRREM---LLQEEEKMIQQRQRLAAVKREL----KVKEMHLQ------DAARRRFLKL 783
+E ++ M +++ EE + +Q+ +++ EL + E +Q +AA R L++
Sbjct: 1369 KELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRI 1428
Query: 784 QQDQQEMELRRLDDEIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQ 843
+++ + + L+ E R +AL + +A+A +R+ E + ++
Sbjct: 1429 EEEIRVVRLQLEATERQRGGAEGELQAL-RARAEEAEAQKRQAQEEAERLRRQVQ----- 1482
Query: 844 SQKTQKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNE 903
++Q+ ++AE E R +A A + R +E+ E AE + E +
Sbjct: 1483 -DESQRKRQAE-VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE--VERA 1538
Query: 904 QDSSCLPRTSQLNDSSEMDPSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHRCQ 963
+ T+Q + +E+ S + S + + + + Q V LR+ RA+ + +
Sbjct: 1539 RQVQVALETAQRSAEAELQ-SKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAE 1597
Score = 52.4 bits (124), Expect = 2e-06
Identities = 55/284 (19%), Positives = 126/284 (44%), Gaps = 16/284 (5%)
Query: 691 ERERIRNDELDYLRERQTVE-------DMQAKVDQQRVEDEAWYQKQELLRKAEETRREM 743
E RIR++ D LR ++ E + A+ +++R E E QK + +R+
Sbjct: 1925 ELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKA 1984
Query: 744 LLQEEEKM---IQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIG 800
L+E E++ +++ +RL + +++ L A ++ L+ ++ +++ + E+
Sbjct: 1985 ALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQEL- 2043
Query: 801 RKNLTENQEALAKEMRADADAYRRKV-DLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFR 859
+ + ++++ ++R +A+A RR + EE EA +++ Q + + + E +
Sbjct: 2044 -QQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2102
Query: 860 LRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSS 919
++ +A A ++ RK ++ A K+ + E+ +T +
Sbjct: 2103 AQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQV 2162
Query: 920 EMDPSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHRCQ 963
E + +T L + E D L ++++ L+ T AR R Q
Sbjct: 2163 EQELTT---LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQ 2203
Score = 50.4 bits (119), Expect = 8e-06
Identities = 60/197 (30%), Positives = 91/197 (46%), Gaps = 37/197 (18%)
Query: 691 ERERIRNDEL---DYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEET----RREM 743
E + +R EL + ++RQ E QQR+ E QEL+R ET ++
Sbjct: 1658 EEQAVRQRELAEQELEKQRQLAEGTA----QQRLAAE-----QELIRLRAETEQGEQQRQ 1708
Query: 744 LLQEEEKMIQQRQRLAAVKRE------LKVK-EMHLQDAARRRFLKLQQDQQEMELRRLD 796
LL+EE +Q+ A KR+ KV+ EM + A++ R + + E +RL+
Sbjct: 1709 LLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLE 1768
Query: 797 DEIGR-KNLTENQ---EALAKEMR-----ADADAYRRKVDLEEHMFHKLIEAGETQSQKT 847
E GR + L E ALA+E + A+ DA R++ + E + KL GE KT
Sbjct: 1769 AEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKT 1828
Query: 848 Q-----KWKEAEGKEFR 859
+ K KEAE + R
Sbjct: 1829 EAEIALKEKEAENERLR 1845
Score = 49.3 bits (116), Expect = 2e-05
Identities = 37/161 (22%), Positives = 85/161 (52%), Gaps = 14/161 (8%)
Query: 686 DYQTQERERIRND----ELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRR 741
+ QT ++E++ + + +L E+ ++ + ++Q++ + E +Q + + KA++ R
Sbjct: 2453 EMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDE--VAKAQQLRE 2510
Query: 742 EMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGR 801
E Q+++ M Q+RQRL A E + ++ ++ RR+ +LQQ +Q+ RR +E+
Sbjct: 2511 EQQRQQQQ-MEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQ---RRQQEEL-- 2564
Query: 802 KNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGET 842
L E + L ++++ + +R + E + + A +T
Sbjct: 2565 --LAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKT 2603
Score = 43.9 bits (102), Expect = 7e-04
Identities = 53/219 (24%), Positives = 100/219 (45%), Gaps = 35/219 (15%)
Query: 690 QERERIRNDELDYLRERQTVEDM-------QAKVDQQRVEDEAWYQKQELLRKAEETRRE 742
+E ER + + LR R E++ QA+ ++Q+ E E +++ + +RE
Sbjct: 1607 RELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRE 1666
Query: 743 MLLQEEEKMIQ-----QRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDD 797
+ QE EK Q +QRLAA + ++ L+ + +Q E + + L++
Sbjct: 1667 LAEQELEKQRQLAEGTAQQRLAAEQELIR--------------LRAETEQGEQQRQLLEE 1712
Query: 798 EIGRKNLTENQEALAKEMRADADAYRRKVDLEEHMF----HKLIEAGETQSQKTQKWKEA 853
E+ R + + A A + R + +A KV E + + E + S+K+++ EA
Sbjct: 1713 ELAR---LQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEA 1769
Query: 854 EGKEFR--LRSAKKASALSDASRKWFLKQEINAAVEHAE 890
E FR A + AL++ +++ E +AA + AE
Sbjct: 1770 EAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAE 1808
Score = 40.4 bits (93), Expect = 0.008
Identities = 49/202 (24%), Positives = 94/202 (46%), Gaps = 41/202 (20%)
Query: 694 RIRNDELDYLRERQTVED----MQAKVDQQR-VEDEAWYQKQ------ELLRKAEETRRE 742
R++ +EL L+ R E+ ++ K + QR +++EA KQ L A+E R
Sbjct: 2212 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARL 2271
Query: 743 MLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRR----FLKLQQDQQEMELRRLDDE 798
L EE+ + QQR A ++ LK K +Q+A R + L+ Q++ + + RRL
Sbjct: 2272 RQLAEED-LAQQR---ALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ-- 2325
Query: 799 IGRKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEF 858
E++E +A+++ + ++R ++ E + ++ + EAE +
Sbjct: 2326 -------EDKEQMAQQLAEETQGFQRTLEAE-------------RQRQLEMSAEAERLKL 2365
Query: 859 RLRSAKKASALSDASRKWFLKQ 880
R+ +A A ++ + F KQ
Sbjct: 2366 RVAEMSRAQARAEEDAQRFRKQ 2387
Score = 35.4 bits (80), Expect = 0.26
Identities = 46/201 (22%), Positives = 87/201 (43%), Gaps = 13/201 (6%)
Query: 688 QTQERERIR-NDELDYLRERQTVEDMQ---AKVDQQRVE---DEAWYQKQELLRKAEETR 740
+ ER R+R +E+ +R + + Q A+ + Q + +EA QK++ +AE R
Sbjct: 1419 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLR 1478
Query: 741 REMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIG 800
R++ + + K + + + VK E + + L+LQ ++ E LR+ + E
Sbjct: 1479 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERA 1538
Query: 801 RKNLTENQEALAKEMR-ADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKWKEAEGKEFR 859
R + Q AL R A+A+ ++ E E Q +EAE + +
Sbjct: 1539 R----QVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1594
Query: 860 LRSAKKASALSDAS-RKWFLK 879
A++A ++ +W LK
Sbjct: 1595 QAEAERAREEAERELERWQLK 1615
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.134 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,251,418
Number of Sequences: 37866
Number of extensions: 1550615
Number of successful extensions: 10573
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 167
Number of HSP's successfully gapped in prelim test: 669
Number of HSP's that attempted gapping in prelim test: 6363
Number of HSP's gapped (non-prelim): 2652
length of query: 970
length of database: 18,247,518
effective HSP length: 112
effective length of query: 858
effective length of database: 14,006,526
effective search space: 12017599308
effective search space used: 12017599308
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.