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Search of human proteins with 221136969
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|221136969 SLIT and NTRK-like family, member 2 [Homo sapiens]
(845 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221136985 SLIT and NTRK-like family, member 2 [Homo sapiens] 1712 0.0
gi|221136981 SLIT and NTRK-like family, member 2 [Homo sapiens] 1712 0.0
gi|221136977 SLIT and NTRK-like family, member 2 [Homo sapiens] 1712 0.0
gi|221136973 SLIT and NTRK-like family, member 2 [Homo sapiens] 1712 0.0
gi|221136969 SLIT and NTRK-like family, member 2 [Homo sapiens] 1712 0.0
gi|221136965 SLIT and NTRK-like family, member 2 [Homo sapiens] 1712 0.0
gi|221136961 SLIT and NTRK-like family, member 2 [Homo sapiens] 1712 0.0
gi|221136957 SLIT and NTRK-like family, member 2 [Homo sapiens] 1712 0.0
gi|33504581 SLIT and NTRK-like family, member 2 [Homo sapiens] 1712 0.0
gi|40217823 SLIT and NTRK-like family, member 5 [Homo sapiens] 799 0.0
gi|27436867 slit and trk like 4 protein [Homo sapiens] 656 0.0
gi|40217820 slit and trk like 3 protein [Homo sapiens] 652 0.0
gi|40217825 slit and trk like 6 [Homo sapiens] 587 e-167
gi|40217817 slit and trk like 1 protein [Homo sapiens] 544 e-154
gi|188528675 slit homolog 1 [Homo sapiens] 146 9e-35
gi|4759146 slit homolog 2 [Homo sapiens] 134 5e-31
gi|11321571 slit homolog 3 [Homo sapiens] 132 1e-30
gi|194440719 chondroadherin-like [Homo sapiens] 125 2e-28
gi|13194201 reticulon 4 receptor precursor [Homo sapiens] 105 1e-22
gi|205277468 leucine rich repeat containing 15 isoform a [Homo s... 105 2e-22
gi|18677767 leucine rich repeat containing 15 isoform b [Homo sa... 105 2e-22
gi|30425563 reticulon 4 receptor-like 2 [Homo sapiens] 100 4e-21
gi|198041768 synleurin [Homo sapiens] 99 1e-20
gi|34577057 fibronectin leucine rich transmembrane protein 1 [Ho... 96 1e-19
gi|38202222 fibronectin leucine rich transmembrane protein 3 pre... 96 1e-19
gi|7019383 fibronectin leucine rich transmembrane protein 3 prec... 96 1e-19
gi|153251229 chondroadherin precursor [Homo sapiens] 96 2e-19
gi|10190722 leucine-rich repeats and transmembrane domains 1 [Ho... 93 9e-19
gi|84781739 leucine-rich repeats and transmembrane domains 2 [Ho... 92 3e-18
gi|30425553 reticulon 4 receptor-like 1 [Homo sapiens] 92 3e-18
>gi|221136985 SLIT and NTRK-like family, member 2 [Homo sapiens]
Length = 845
Score = 1712 bits (4435), Expect = 0.0
Identities = 845/845 (100%), Positives = 845/845 (100%)
Query: 1 MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP
Sbjct: 1 MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
Query: 61 QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN
Sbjct: 61 QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
Query: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF
Sbjct: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
Query: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE
Sbjct: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
Query: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK
Sbjct: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
Query: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ
Sbjct: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
Query: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT
Sbjct: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
Query: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN
Sbjct: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
Query: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL
Sbjct: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
Query: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600
KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR
Sbjct: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600
Query: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660
SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL
Sbjct: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660
Query: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720
DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY
Sbjct: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720
Query: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780
SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP
Sbjct: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780
Query: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840
KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT
Sbjct: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840
Query: 841 AISQL 845
AISQL
Sbjct: 841 AISQL 845
>gi|221136981 SLIT and NTRK-like family, member 2 [Homo sapiens]
Length = 845
Score = 1712 bits (4435), Expect = 0.0
Identities = 845/845 (100%), Positives = 845/845 (100%)
Query: 1 MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP
Sbjct: 1 MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
Query: 61 QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN
Sbjct: 61 QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
Query: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF
Sbjct: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
Query: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE
Sbjct: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
Query: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK
Sbjct: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
Query: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ
Sbjct: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
Query: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT
Sbjct: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
Query: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN
Sbjct: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
Query: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL
Sbjct: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
Query: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600
KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR
Sbjct: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600
Query: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660
SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL
Sbjct: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660
Query: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720
DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY
Sbjct: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720
Query: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780
SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP
Sbjct: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780
Query: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840
KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT
Sbjct: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840
Query: 841 AISQL 845
AISQL
Sbjct: 841 AISQL 845
>gi|221136977 SLIT and NTRK-like family, member 2 [Homo sapiens]
Length = 845
Score = 1712 bits (4435), Expect = 0.0
Identities = 845/845 (100%), Positives = 845/845 (100%)
Query: 1 MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP
Sbjct: 1 MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
Query: 61 QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN
Sbjct: 61 QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
Query: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF
Sbjct: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
Query: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE
Sbjct: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
Query: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK
Sbjct: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
Query: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ
Sbjct: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
Query: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT
Sbjct: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
Query: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN
Sbjct: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
Query: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL
Sbjct: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
Query: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600
KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR
Sbjct: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600
Query: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660
SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL
Sbjct: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660
Query: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720
DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY
Sbjct: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720
Query: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780
SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP
Sbjct: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780
Query: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840
KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT
Sbjct: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840
Query: 841 AISQL 845
AISQL
Sbjct: 841 AISQL 845
>gi|221136973 SLIT and NTRK-like family, member 2 [Homo sapiens]
Length = 845
Score = 1712 bits (4435), Expect = 0.0
Identities = 845/845 (100%), Positives = 845/845 (100%)
Query: 1 MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP
Sbjct: 1 MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
Query: 61 QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN
Sbjct: 61 QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
Query: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF
Sbjct: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
Query: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE
Sbjct: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
Query: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK
Sbjct: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
Query: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ
Sbjct: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
Query: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT
Sbjct: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
Query: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN
Sbjct: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
Query: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL
Sbjct: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
Query: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600
KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR
Sbjct: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600
Query: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660
SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL
Sbjct: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660
Query: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720
DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY
Sbjct: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720
Query: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780
SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP
Sbjct: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780
Query: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840
KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT
Sbjct: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840
Query: 841 AISQL 845
AISQL
Sbjct: 841 AISQL 845
>gi|221136969 SLIT and NTRK-like family, member 2 [Homo sapiens]
Length = 845
Score = 1712 bits (4435), Expect = 0.0
Identities = 845/845 (100%), Positives = 845/845 (100%)
Query: 1 MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP
Sbjct: 1 MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
Query: 61 QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN
Sbjct: 61 QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
Query: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF
Sbjct: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
Query: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE
Sbjct: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
Query: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK
Sbjct: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
Query: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ
Sbjct: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
Query: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT
Sbjct: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
Query: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN
Sbjct: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
Query: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL
Sbjct: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
Query: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600
KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR
Sbjct: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600
Query: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660
SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL
Sbjct: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660
Query: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720
DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY
Sbjct: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720
Query: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780
SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP
Sbjct: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780
Query: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840
KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT
Sbjct: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840
Query: 841 AISQL 845
AISQL
Sbjct: 841 AISQL 845
>gi|221136965 SLIT and NTRK-like family, member 2 [Homo sapiens]
Length = 845
Score = 1712 bits (4435), Expect = 0.0
Identities = 845/845 (100%), Positives = 845/845 (100%)
Query: 1 MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP
Sbjct: 1 MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
Query: 61 QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN
Sbjct: 61 QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
Query: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF
Sbjct: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
Query: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE
Sbjct: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
Query: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK
Sbjct: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
Query: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ
Sbjct: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
Query: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT
Sbjct: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
Query: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN
Sbjct: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
Query: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL
Sbjct: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
Query: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600
KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR
Sbjct: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600
Query: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660
SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL
Sbjct: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660
Query: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720
DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY
Sbjct: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720
Query: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780
SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP
Sbjct: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780
Query: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840
KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT
Sbjct: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840
Query: 841 AISQL 845
AISQL
Sbjct: 841 AISQL 845
>gi|221136961 SLIT and NTRK-like family, member 2 [Homo sapiens]
Length = 845
Score = 1712 bits (4435), Expect = 0.0
Identities = 845/845 (100%), Positives = 845/845 (100%)
Query: 1 MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP
Sbjct: 1 MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
Query: 61 QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN
Sbjct: 61 QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
Query: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF
Sbjct: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
Query: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE
Sbjct: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
Query: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK
Sbjct: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
Query: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ
Sbjct: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
Query: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT
Sbjct: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
Query: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN
Sbjct: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
Query: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL
Sbjct: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
Query: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600
KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR
Sbjct: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600
Query: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660
SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL
Sbjct: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660
Query: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720
DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY
Sbjct: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720
Query: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780
SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP
Sbjct: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780
Query: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840
KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT
Sbjct: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840
Query: 841 AISQL 845
AISQL
Sbjct: 841 AISQL 845
>gi|221136957 SLIT and NTRK-like family, member 2 [Homo sapiens]
Length = 845
Score = 1712 bits (4435), Expect = 0.0
Identities = 845/845 (100%), Positives = 845/845 (100%)
Query: 1 MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP
Sbjct: 1 MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
Query: 61 QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN
Sbjct: 61 QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
Query: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF
Sbjct: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
Query: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE
Sbjct: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
Query: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK
Sbjct: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
Query: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ
Sbjct: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
Query: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT
Sbjct: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
Query: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN
Sbjct: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
Query: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL
Sbjct: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
Query: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600
KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR
Sbjct: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600
Query: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660
SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL
Sbjct: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660
Query: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720
DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY
Sbjct: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720
Query: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780
SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP
Sbjct: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780
Query: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840
KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT
Sbjct: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840
Query: 841 AISQL 845
AISQL
Sbjct: 841 AISQL 845
>gi|33504581 SLIT and NTRK-like family, member 2 [Homo sapiens]
Length = 845
Score = 1712 bits (4435), Expect = 0.0
Identities = 845/845 (100%), Positives = 845/845 (100%)
Query: 1 MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP
Sbjct: 1 MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
Query: 61 QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN
Sbjct: 61 QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
Query: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF
Sbjct: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
Query: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE
Sbjct: 181 VLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
Query: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK
Sbjct: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
Query: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ
Sbjct: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
Query: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT
Sbjct: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
Query: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN
Sbjct: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
Query: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL
Sbjct: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
Query: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600
KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR
Sbjct: 541 KDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPR 600
Query: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660
SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL
Sbjct: 601 SLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNL 660
Query: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720
DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY
Sbjct: 661 DVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSY 720
Query: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780
SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP
Sbjct: 721 SNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLP 780
Query: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840
KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT
Sbjct: 781 KRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQT 840
Query: 841 AISQL 845
AISQL
Sbjct: 841 AISQL 845
>gi|40217823 SLIT and NTRK-like family, member 5 [Homo sapiens]
Length = 958
Score = 799 bits (2063), Expect = 0.0
Identities = 440/918 (47%), Positives = 584/918 (63%), Gaps = 106/918 (11%)
Query: 27 DICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYS 86
+IC C CEEK+ +L ++CEN+G ++S + PP++ IY L L+GNLL RLYPNEFVNY+
Sbjct: 46 EICDNACPCEEKDGILTVSCENRGIISLSEISPPRFPIYHLLLSGNLLNRLYPNEFVNYT 105
Query: 87 NAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYI 146
A LHLG+N +Q+I TGAF GL+ L+RLHLNNNKLE+LR+DTFLGLE+LEYLQ DYNYI
Sbjct: 106 GASILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYI 165
Query: 147 SAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHIG 206
S IE AF KL+ L+VLILNDNLL SLP+N+FRFV LTHLDLRGNRLK++P+ G+L+H+
Sbjct: 166 SVIEPNAFGKLHLLQVLILNDNLLSSLPNNLFRFVPLTHLDLRGNRLKLLPYVGLLQHMD 225
Query: 207 GIMEIQLEENPWNCTCDLLPLKAWLDTIT--VFVGEIVCETPFRLHGKDVTQLTRQDLCP 264
++E+QLEENPWNC+C+L+ LK WLD+I+ VG++VCETPFRLHG+D+ ++++Q+LCP
Sbjct: 226 KVVELQLEENPWNCSCELISLKDWLDSISYSALVGDVVCETPFRLHGRDLDEVSKQELCP 285
Query: 265 RKSASDSSQRGS---------HADTHVQRLSPTMNPALN--PTRAPKASRPP-KMRNRPT 312
R+ SD R H T + A+ P + PK +R P K R RPT
Sbjct: 286 RRLISDYEMRPQTPLSTTGYLHTTPASVNSVATSSSAVYKPPLKPPKGTRQPNKPRVRPT 345
Query: 313 PRVTVSKDR--QSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDL 370
R SKD ++GP + YQTKSPVPL CP++C C Q SD GLNVNCQERK +I++L
Sbjct: 346 SRQP-SKDLGYSNYGPSIAYQTKSPVPLECPTACSCNLQISDLGLNVNCQERKIESIAEL 404
Query: 371 QPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYL 430
QPKP +PKK+YLT NY+ V + D LE + LDLLHLGNNRI++IQ+ AF +LT+LRRLYL
Sbjct: 405 QPKPYNPKKMYLTENYIAVVRRTDFLEATGLDLLHLGNNRISMIQDRAFGDLTNLRRLYL 464
Query: 431 NGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNI 490
NGN +E L P +F GLQSLQYL+L+YN+I+EI+ TFD + NLQLLFLNNNLL+++P +
Sbjct: 465 NGNRIERLSPELFYGLQSLQYLFLQYNLIREIQSGTFDPVPNLQLLFLNNNLLQAMPSGV 524
Query: 491 FGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSP 550
F G L RLNLR+NHF+ LPV GVLDQL + IQIDL +NPWDCTCDI+G+K W E
Sbjct: 525 FSGLTLLRLNLRSNHFTSLPVSGVLDQLKSLIQIDLHDNPWDCTCDIVGMKLWVEQLKVG 584
Query: 551 VIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMN----------------H 594
V+++EV C++P K A ++ + E +CPD ++ T + +
Sbjct: 585 VLVDEVICKAPKKFAETDMRSIKSELLCPDYSDVVVSTPTPSSIQVPARTSAVTPAVRLN 644
Query: 595 NTDTPRSLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVP 654
+T P SL + + VPLSVLIL LL+VFI+SV AGLFV V+KRRK S
Sbjct: 645 STGAPASLGAGGGA-----SSVPLSVLILSLLLVFIMSVFVAAGLFVLVMKRRKKNQSDH 699
Query: 655 RNTNNLDVSSFQLQYGSY----------NTETHDK---------TDGHVYNYIPPPVGQM 695
+TNN DVSSF +QY Y + H + GHVY YIP P+G M
Sbjct: 700 TSTNNSDVSSFNMQYSVYGGGGGTGGHPHAHVHHRGPALPKVKTPAGHVYEYIPHPLGHM 759
Query: 696 CQNPIYMQKEGDPVAYYRNLQEF-----SYSNLEEKKEEP-------------------- 730
C+NPIY +EG+ V Y++L E S +L+++++ P
Sbjct: 760 CKNPIYRSREGNSVEDYKDLHELKVTYSSNHHLQQQQQPPPPPQQPQQQPPPQLQLQPGE 819
Query: 731 ---------ATPAYTISATELLEKQATP-REPELLYQNIAERVKELPSA----GLVHYNF 776
+PAY++S E E +P ++ + Y+ I E K + L Y
Sbjct: 820 EERRESHHLRSPAYSVSTIEPREDLLSPVQDADRFYRGILEPDKHCSTTPAGNSLPEYPK 879
Query: 777 --CTLPKRQFAPSYESRRQNQ--------DRINKTVLYGTPRKCFVGQSKPNHPLLQAKP 826
C+ F+P+Y+ RR +Q R+ + VLY P FV ++ + L+AK
Sbjct: 880 FPCSPAAYTFSPNYDLRRPHQYLHPGAGDSRLREPVLYSPPSAVFVEPNRNEYLELKAKL 939
Query: 827 QSEPDYLEVLEKQTAISQ 844
EPDYLEVLEKQT SQ
Sbjct: 940 NVEPDYLEVLEKQTTFSQ 957
>gi|27436867 slit and trk like 4 protein [Homo sapiens]
Length = 837
Score = 656 bits (1692), Expect = 0.0
Identities = 373/868 (42%), Positives = 515/868 (59%), Gaps = 60/868 (6%)
Query: 5 VWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRI 64
+W +L+ + +IC + C C ENVL +NCE + L+PP
Sbjct: 3 LWLFLILSALISSTNADSDISVEICNV-CSCVSVENVLYVNCEKVSVYRPNQLKPPWSNF 61
Query: 65 YQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEI 124
Y L N L LYPN F+N+S+AV+LHLGNN LQ I GAF GL LK+LHLNNN+L+I
Sbjct: 62 YHLNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKI 121
Query: 125 LREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLT 184
LR DTFLG+E+LEYLQADYN I IE GAF+KL+KLKVLILNDNL+ LP N+FRF LT
Sbjct: 122 LRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFRFASLT 181
Query: 185 HLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTI--TVFVGEIV 242
HLD+RGNR++ +P+ GVLEHIG ++E+QLE+NPWNC+CDLLPLKAWL+ + +++GE +
Sbjct: 182 HLDIRGNRIQKLPYIGVLEHIGRVVELQLEDNPWNCSCDLLPLKAWLENMPYNIYIGEAI 241
Query: 243 CETPFRLHGKDVTQLTRQDLCPRKSASDSSQR---------------GSHADTHVQRLSP 287
CETP L+G+ + + +Q+LCP + SD R G T + RL
Sbjct: 242 CETPSDLYGRLLKETNKQELCPMGTGSDFDVRILPPSQLENGYTTPNGHTTQTSLHRLV- 300
Query: 288 TMNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCT 347
T+ PK + P K+ + +++ I+ YQT+ P CP+ C C
Sbjct: 301 --------TKPPKTTNPSKISGIVAGKALSNRN---LSQIVSYQTRVPPLTPCPAPCFCK 349
Query: 348 SQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLG 407
+ SD GL+VNCQE+ ++S+L PKP + KKL++ GN ++ V +D ++ LDLLHLG
Sbjct: 350 THPSDLGLSVNCQEKNIQSMSELIPKPLNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLG 409
Query: 408 NNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTF 467
+N+I VI+ F NLT+LRRLYLNGN +E LYP +F GL +LQYLYLEYN+IKEI TF
Sbjct: 410 SNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEISAGTF 469
Query: 468 DALINLQLLFLNNNLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQ 527
D++ NLQLL+LNNNLL+SLP IF G L RLNLRNN F +LPV GVLDQL + QIDL+
Sbjct: 470 DSMPNLQLLYLNNNLLKSLPVYIFSGAPLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLE 529
Query: 528 ENPWDCTCDIMGLKDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAIC------PDS 581
NPWDCTCD++ LK W E + +++ E+ CE+P + A LK L E +C P +
Sbjct: 530 GNPWDCTCDLVALKLWVEKLSDGIVVKELKCETPVQFANIELKSLKNEILCPKLLNKPSA 589
Query: 582 PNLSDGTVLSMNHNTDTPRSLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFV 641
P S ++ TP SP P VPLS+LIL +LVV IL+V L V
Sbjct: 590 PFTSPAPAITFT----TPLGPIRSPPGGP-----VPLSILILSILVVLILTVFVAFCLLV 640
Query: 642 FVLKRRKGVPSVPRNTNNLDVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIY 701
FVL+R K N D S QLQ ++ +T+ K +IP + QM ++
Sbjct: 641 FVLRRNKKPTVKHEGLGNPDCGSMQLQLRKHDHKTNKKDGLSTEAFIPQTIEQMSKSHTC 700
Query: 702 MQKEGDPVAYYRNL--QEFSYSNLEEKKEE--PATPAYTISATELLEKQATPREPELLYQ 757
KE + + + Q+ N+ +K+++ +S + L++ R+ + Q
Sbjct: 701 GLKESETGFMFSDPPGQKVVMRNVADKEKDLLHVDTRKRLSTIDELDELFPSRDSNVFIQ 760
Query: 758 NIAERVKELPSAGLVHYNFCTLPKRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKP 817
N E KE S G+ + P++Q P +S+ K+++ G K V Q K
Sbjct: 761 NFLESKKEYNSIGVSGFEI-RYPEKQ--PDKKSK--------KSLIGGNHSKIVVEQRKS 809
Query: 818 NHPLLQAKPQSEPDYLEVLEKQTAISQL 845
+ L+AK QS PDYL+VLE+QTA++++
Sbjct: 810 EYFELKAKLQSSPDYLQVLEEQTALNKI 837
>gi|40217820 slit and trk like 3 protein [Homo sapiens]
Length = 977
Score = 652 bits (1682), Expect = 0.0
Identities = 358/815 (43%), Positives = 492/815 (60%), Gaps = 66/815 (8%)
Query: 5 VWFLSVLTVA-----GILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQP 59
+W + + T+A I E + + C C CE KE++ +I+C++KGFT +S +
Sbjct: 15 LWIILLSTIALGWTTPIPLIEDSEEIDEPCFDPCYCEVKESLFHIHCDSKGFTNISQITE 74
Query: 60 PQYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNN 119
R ++L+L N + +LY N F++ +NAV+++LGNN LQ+I+TGAF+GLK LKRL+L+
Sbjct: 75 FWSRPFKLYLQRNSMRKLYTNSFLHLNNAVSINLGNNALQDIQTGAFNGLKILKRLYLHE 134
Query: 120 NKLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFR 179
NKL++ R DTFLGLESLEYLQADYN I IE+GAF L+KL+VLILNDNL+ LP+N+F+
Sbjct: 135 NKLDVFRNDTFLGLESLEYLQADYNVIKRIESGAFRNLSKLRVLILNDNLIPMLPTNLFK 194
Query: 180 FVLLTHLDLRGNRLKVMPFAGVLEHIG-GIMEIQLEENPWNCTCDLLPLKAWLDTI--TV 236
V LTHLDLRGNRLKV+ + G+L+HIG +ME+QLEENPWNCTC+++ LK+WL+ I T
Sbjct: 195 AVSLTHLDLRGNRLKVLFYRGMLDHIGRSLMELQLEENPWNCTCEIVQLKSWLERIPYTA 254
Query: 237 FVGEIVCETPFRLHGKDVTQLTRQDLCPRKSASD--SSQRGSHADTHVQRLSPTM----- 289
VG+I CETPF HGKD+ ++ + +LCP S S+ +S H+ + + PT
Sbjct: 255 LVGDITCETPFHFHGKDLREIRKTELCPLLSDSEVEASLGIPHSSSSKENAWPTKPSSML 314
Query: 290 ---------------NPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKS 334
N PT+ P+ RPP P PI YQT+
Sbjct: 315 SSVHFTASSVEYKSSNKQPKPTKQPRTPRPPSTSQALYPGPNQP-------PIAPYQTRP 367
Query: 335 PVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKND 394
P+P+ CP+ C C +D GL VNC+ER F NIS+L P+P + KKLYL+ N +Q +Y++D
Sbjct: 368 PIPIICPTGCTCNLHINDLGLTVNCKERGFNNISELLPRPLNAKKLYLSSNLIQKIYRSD 427
Query: 395 LLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYL 454
+SSLDLLHLGNNRI+ +Q+GAF NL +L+ L+LNGN +E L P MF GLQSL YLY
Sbjct: 428 FWNFSSLDLLHLGNNRISYVQDGAFINLPNLKSLFLNGNDIEKLTPGMFRGLQSLHYLYF 487
Query: 455 EYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGV 514
E+NVI+EI+P F + NL+LLFLNNNLLR+LP + F GT+L RLNLR N+F +LPV GV
Sbjct: 488 EFNVIREIQPAAFSLMPNLKLLFLNNNLLRTLPTDAFAGTSLARLNLRKNYFLYLPVAGV 547
Query: 515 LDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVTCESPAKHAGEILKFLGR 574
L+ L A +QIDL ENPWDCTCD++ K W E +S ++ +V C SP ++ +
Sbjct: 548 LEHLNAIVQIDLNENPWDCTCDLVPFKQWIETISSVSVVGDVLCRSPENLTHRDVRTIEL 607
Query: 575 EAICPD----SPNLSDGTVLSMNHNTDTPRSLSVSPSSYPELHTEVPLSVLILGLLVVFI 630
E +CP+ +P +H P S SP + VPLSVLIL LLV+F
Sbjct: 608 EVLCPEMLHVAPAGESPAQPGDSHLIGAP--TSASPYEFSPPGGPVPLSVLILSLLVLFF 665
Query: 631 LSVCFGAGLFVFVL-KRRKGVPSVPRNTNNLDVSSFQLQY-----------------GSY 672
+V AGLF +VL +RRK +P + +D++ Q+Q G
Sbjct: 666 SAVFVAAGLFAYVLRRRRKKLPFRSKRQEGVDLTGIQMQCHRLFEDGGGGGGGSGGGGRP 725
Query: 673 NTETHDKTD--GHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSYSNLEEKKEEP 730
+ +K GHVY YIP PV QMC NPIY +E + VA + S + P
Sbjct: 726 TLSSPEKAPPVGHVYEYIPHPVTQMCNNPIYKPREEEEVAVSSAQEAGSAERGGPGTQPP 785
Query: 731 ATPAYTISATELLEKQATPREPELLYQNIAERVKE 765
+ + + E TP+E Y+ + E+ KE
Sbjct: 786 GMGEALLGSEQFAE---TPKENHSNYRTLLEKEKE 817
Score = 35.4 bits (80), Expect = 0.22
Identities = 30/87 (34%), Positives = 47/87 (54%), Gaps = 7/87 (8%)
Query: 761 ERVKELP-SAGLVHYNFCTLPKRQ----FAPSYESRRQNQD-RINKTVLYGTPRKCFVGQ 814
ER + P + G V + T+PK + P + QD R+ +T+L+ + Q
Sbjct: 888 ERPQPAPCTVGFVDCLYGTVPKLKELHVHPPGMQYPDLQQDARLKETLLFSAGKGFTDHQ 947
Query: 815 SKPNHPL-LQAKPQSEPDYLEVLEKQT 840
++ + L L+AK Q++PDYLEVLEK T
Sbjct: 948 TQKSDYLELRAKLQTKPDYLEVLEKTT 974
>gi|40217825 slit and trk like 6 [Homo sapiens]
Length = 841
Score = 587 bits (1514), Expect = e-167
Identities = 346/860 (40%), Positives = 505/860 (58%), Gaps = 49/860 (5%)
Query: 5 VWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRI 64
+++ S+L + +++ C C CEEK+ + INCE KG VS + P R
Sbjct: 7 LFYSSLLACISLHSQTPVLSSRGSCDSLCNCEEKDGTMLINCEAKGIKMVSEISVPPSRP 66
Query: 65 YQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEI 124
+QL L N LT L+ N+F +NA+++HLG N + +I GAF+GL LK+LH+N+N LEI
Sbjct: 67 FQLSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEI 126
Query: 125 LREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLT 184
L+EDTF GLE+LE+LQAD N+I+ IE AFSKLN+LKVLILNDN + SLP N+FRFV LT
Sbjct: 127 LKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVPLT 186
Query: 185 HLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITV--FVGEIV 242
HLDLRGN+L+ +P+ G LEHIG I+++QLE+N W C CDLL LK WL+ + +G++V
Sbjct: 187 HLDLRGNQLQTLPYVGFLEHIGRILDLQLEDNKWACNCDLLQLKTWLENMPPQSIIGDVV 246
Query: 243 CETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPKAS 302
C +P G +++L ++ +CP + + S H+ S ++N + T+
Sbjct: 247 CNSPPFFKGSILSRLKKESICPTPPVYEEHEDPS-GSLHLAATS-SINDSRMSTKTTSIL 304
Query: 303 RPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQER 362
+ P P +T T+ P P CP C C S +GL ++CQER
Sbjct: 305 KLPTKAPGLIPYITKPS------------TQLPGPY-CPIPCNC-KVLSPSGLLIHCQER 350
Query: 363 KFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNL 422
++SDL+P P +P+KL L GN + ++ K+DL+EY +L++LHLGNNRI V++EG+F NL
Sbjct: 351 NIESLSDLRPPPQNPRKLILAGNIIHSLMKSDLVEYFTLEMLHLGNNRIEVLEEGSFMNL 410
Query: 423 TSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNL 482
T L++LYLNGN+L L MF GL +L+YLYLEYN IKEI P TF+ + L++L+LNNNL
Sbjct: 411 TRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIKEILPGTFNPMPKLKVLYLNNNL 470
Query: 483 LRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKD 542
L+ LP +IF G LT++NL+ N F+HLPV +LD L QIDL++NPWDC+CD++GL+
Sbjct: 471 LQVLPPHIFSGVPLTKVNLKTNQFTHLPVSNILDDLDLLTQIDLEDNPWDCSCDLVGLQQ 530
Query: 543 WTEHANSPVIINEVTCESPAKHAGEILKFLGREAICP---DSPNLSDGTVLSMNHNTDTP 599
W + + + +++ C SP + LK L E +CP ++P++ T M T
Sbjct: 531 WIQKLSKNTVTDDILCTSPGHLDKKELKALNSEILCPGLVNNPSMPTQTSYLM--VTTPA 588
Query: 600 RSLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNN 659
+ + + + L VPLSVLILGLL++FI V AG+ V VL RR+ +
Sbjct: 589 TTTNTADTILRSLTDAVPLSVLILGLLIMFITIVFCAAGIVVLVLHRRRRYKKKQVDEQM 648
Query: 660 LDVSSFQLQYGSY-NTETHDKTD---GHVY-NYIPPPVGQMCQNPIYMQKEGDPVAYYRN 714
D S LQY Y + TH T+ +Y ++ P+ + ++P + K + RN
Sbjct: 649 RDNSPVHLQYSMYGHKTTHHTTERPSASLYEQHMVSPMVHVYRSPSFGPKHLEE-EEERN 707
Query: 715 LQEFS------YSNLEEKKEEPATPA-----YTISATELLEKQATPREPELLYQNIAERV 763
+E S S LE++ P T + T +TE L Q + LY+NI E+
Sbjct: 708 EKEGSDAKHLQRSLLEQENHSPLTGSNMKYKTTNQSTEFLSFQ----DASSLYRNILEKE 763
Query: 764 KELPSAGLVHYNFCTLPKRQFAPSYESR---RQNQDRINKTVLYGTPRKCFVGQSKPNHP 820
+EL G+ Y + Q P E+ + ++ +T++Y PRK V Q+K +
Sbjct: 764 RELQQLGITEYLRKNI--AQLQPDMEAHYPGAHEELKLMETLMYSRPRKVLVEQTKNEYF 821
Query: 821 LLQAKPQSEPDYLEVLEKQT 840
L+A +EPDYLEVLE+QT
Sbjct: 822 ELKANLHAEPDYLEVLEQQT 841
>gi|40217817 slit and trk like 1 protein [Homo sapiens]
Length = 696
Score = 544 bits (1401), Expect = e-154
Identities = 289/655 (44%), Positives = 405/655 (61%), Gaps = 26/655 (3%)
Query: 27 DICKIR-CLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNY 85
D+CK + C C E E L+++CE KGFT++ P + Y LFL+GN LTRL+PNEF N+
Sbjct: 22 DVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANF 81
Query: 86 SNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNY 145
NAV+LH+ NNGL EI GAF GL+ +KRLH+NNNK++ R+ TFLGL+ LEYLQAD+N
Sbjct: 82 YNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNL 141
Query: 146 ISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHI 205
+ I+ GAF LNKL+VLILNDNL+ +LP+NVF++V +THLDLRGNRLK +P+ VLE I
Sbjct: 142 LRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQI 201
Query: 206 GGIMEIQLEENPWNCTCDLLPLKAWLDTI--TVFVGEIVCETPFRLHGKDVTQLTRQDLC 263
GI EI LE+NPW+CTCDLL LK WL+ I +G +VCE P RL GKD+ + T QDLC
Sbjct: 202 PGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLC 261
Query: 264 PRKSASDSSQRGSHA--DTHVQRLSPT----------MNPALNPTRAPKASRPPKMRNRP 311
P K+ DSS A +T PT P P K +++ RP
Sbjct: 262 PLKNRVDSSLPAPPAQEETFAPGPLPTPFKTNGQEDHATPGSAPNGGTKIPGNWQIKIRP 321
Query: 312 TPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQ 371
T + R P+ L CP C C +GL +NC R ++++DL+
Sbjct: 322 TAAIATGSSRNK--PL-------ANSLPCPGGCSC-DHIPGSGLKMNCNNRNVSSLADLK 371
Query: 372 PKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLN 431
PK ++ ++L+L N + ++ K+ ++Y +L LL LGNN IA ++ F NL LR LY++
Sbjct: 372 PKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMD 431
Query: 432 GNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIF 491
NYL+ L F GLQ+L+YL +EYN I+ I P TF+A+ L++L LNNNLLRSLP ++F
Sbjct: 432 SNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVF 491
Query: 492 GGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPV 551
G +L++L+L NN+F +LPV GVLDQL + IQIDL NPW+C+C I+ K W E S V
Sbjct: 492 AGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWAERLGSEV 551
Query: 552 IINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPRSLSVSPSSYPE 611
+++++ CE+P + L + ICP T+ S + N+ +SY +
Sbjct: 552 LMSDLKCETPVNFFRKDFMLLSNDEICPQLYARISPTLTSHSKNSTGLAETGTHSNSYLD 611
Query: 612 LHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNLDVSSFQ 666
+ V +SVL+ GLL+VF+ S G+ VF+L+ RK N++ +++S Q
Sbjct: 612 T-SRVSISVLVPGLLLVFVTSAFTVVGMLVFILRNRKRSKRRDANSSASEINSLQ 665
>gi|188528675 slit homolog 1 [Homo sapiens]
Length = 1534
Score = 146 bits (368), Expect = 9e-35
Identities = 144/543 (26%), Positives = 212/543 (39%), Gaps = 105/543 (19%)
Query: 29 CKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNA 88
C C C ++C G + P +L LNGN +TR++ N+F
Sbjct: 34 CPALCTCTGT----TVDCHGTGLQAIPKNIPRNTE--RLELNGNNITRIHKNDFAGLKQL 87
Query: 89 VTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISA 148
L L N + + GAF +K L+RL LN N+L +L E F ++L L N I A
Sbjct: 88 RVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQA 147
Query: 149 IEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVL-LTHLDLRGNRLKVMPFAGVLEHIGG 207
I AF LK L L+ N + + FR + L L L N + +P + H+
Sbjct: 148 IPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSS-FNHMPK 206
Query: 208 IMEIQLEENPWNCTCDLLPLKAWL---DTITVFVGEIVCETPFRLHGKDVTQLTRQDLCP 264
+ +L N C C L L WL TI +F C P L G +V ++ + +
Sbjct: 207 LRTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFT---QCSGPASLRGLNVAEVQKSEF-- 261
Query: 265 RKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSF 324
S S + G P T+S
Sbjct: 262 --SCSGQGEAGR-----------------------------------VPTCTLSSG---- 280
Query: 325 GPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTG 384
+CP+ C C+ NG+ V+C+ + T I P+ + +L L G
Sbjct: 281 --------------SCPAMCTCS-----NGI-VDCRGKGLTAIPANLPETMTEIRLELNG 320
Query: 385 NYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFD 444
++++ Y L + L NN+IA I AF L SL L L GN + L +F
Sbjct: 321 --IKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFG 378
Query: 445 GLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTRLNLRNN 504
GL +LQ L L N I I+P F L NL LL L +N ++SL
Sbjct: 379 GLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSL------------------ 420
Query: 505 HFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVTCESPAKH 564
KG L A + L +NP+ C C++ L D+ +P+ + C SP +
Sbjct: 421 ------AKGTFTSLRAIQTLHLAQNPFICDCNLKWLADFLR--TNPIETSGARCASPRRL 472
Query: 565 AGE 567
A +
Sbjct: 473 ANK 475
Score = 110 bits (275), Expect = 5e-24
Identities = 114/454 (25%), Positives = 172/454 (37%), Gaps = 65/454 (14%)
Query: 29 CKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNA 88
C C C ++C KG T + P +L LNG + + P F Y
Sbjct: 282 CPAMCTCSNGI----VDCRGKGLTAIPANLPETMTEIRLELNG--IKSIPPGAFSPYRKL 335
Query: 89 VTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISA 148
+ L NN + EI AF GL++L L L NK+ L F GL +L+ L + N I+
Sbjct: 336 RRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINC 395
Query: 149 IEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHIGGI 208
I AF L L +L L DN + SL G + I
Sbjct: 396 IRPDAFQDLQNLSLLSLYDNKIQSLAK------------------------GTFTSLRAI 431
Query: 209 MEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDLCPRKSA 268
+ L +NP+ C C+L L +L T + C +P RL K + Q+ +K
Sbjct: 432 QTLHLAQNPFICDCNLKWLADFLRTNPIETSGARCASPRRLANKRIGQIK-----SKKFR 486
Query: 269 SDSSQRGSHADTHVQRLSPTMNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSFGPIM 328
+ ++ T +L+ N + V K R +
Sbjct: 487 CSAKEQYFIPGTEDYQLNSECNSDV---------------------VCPHKCRCEANVVE 525
Query: 329 VYQTK-SPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYL 387
K + +P P S L +N E + + K T KK+ L+ N +
Sbjct: 526 CSSLKLTKIPERIPQSTA--------ELRLNNNEISILEATGMFKKLTHLKKINLSNNKV 577
Query: 388 QTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQ 447
+ +S+ LHL N++ I+ G F L LR L L N + ++ F GL+
Sbjct: 578 SEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLR 637
Query: 448 SLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNN 481
+++ L L N I + P FD L +L L L N
Sbjct: 638 NVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 95.9 bits (237), Expect = 1e-19
Identities = 83/296 (28%), Positives = 120/296 (40%), Gaps = 26/296 (8%)
Query: 340 CPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYS 399
CP+ C CT G V+C I P+ T ++L L GN + ++KND
Sbjct: 34 CPALCTCT------GTTVDCHGTGLQAIPKNIPRNT--ERLELNGNNITRIHKNDFAGLK 85
Query: 400 SLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVI 459
L +L L N+I ++ GAF ++ L RL LN N L +L +F Q+L L L N I
Sbjct: 86 QLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAI 145
Query: 460 KEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGG-TALTRLNLRNNHFSHLPVKGVLDQL 518
+ I F +L+ L L+ N + + + F L L L NN+ + +PV + +
Sbjct: 146 QAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSS-FNHM 204
Query: 519 PAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVTCESPAKHAG----EILKF--- 571
P L N C C + L W P I C PA G E+ K
Sbjct: 205 PKLRTFRLHSNHLFCDCHLAWLSQWLR--QRPTIGLFTQCSGPASLRGLNVAEVQKSEFS 262
Query: 572 ------LGREAICPDSPNLSDGTVLSMNHNTD-TPRSLSVSPSSYPELHTEVPLSV 620
GR C S N D + L+ P++ PE TE+ L +
Sbjct: 263 CSGQGEAGRVPTCTLSSGSCPAMCTCSNGIVDCRGKGLTAIPANLPETMTEIRLEL 318
Score = 92.0 bits (227), Expect = 2e-18
Identities = 100/440 (22%), Positives = 182/440 (41%), Gaps = 59/440 (13%)
Query: 134 ESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVL-LTHLDLRGNR 192
E++ ++ + N I +I GAFS KL+ + L++N + + + F+ + L L L GN+
Sbjct: 309 ETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNK 368
Query: 193 LKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGK 252
+ +P GV + + + L N NC + A+ D + + L+
Sbjct: 369 ITDLP-RGVFGGLYTLQLLLLNANKINC----IRPDAFQDLQNLSL--------LSLYDN 415
Query: 253 DVTQLTRQDLCPRKSASDS--SQRGSHADTHVQRLSPTMNPALNPTRAPKASRPPKMRNR 310
+ L + ++ +Q D +++ L+ + T + + P ++ N+
Sbjct: 416 KIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWLADFLRTNPIETSGARCASPRRLANK 475
Query: 311 PTPRVTVSKDR-----QSFGP-IMVYQTKSPV--PLTCPSSCVCTSQSSDNGLNVNCQER 362
++ K R Q F P YQ S + CP C C + V C
Sbjct: 476 RIGQIKSKKFRCSAKEQYFIPGTEDYQLNSECNSDVVCPHKCRCEANV------VECSSL 529
Query: 363 KFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLE-YSSLDLLHLGNNRIAVIQEGAFTN 421
K T I + P+ T+ +L L N + + + + + L ++L NN+++ I++GAF
Sbjct: 530 KLTKIPERIPQSTA--ELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEG 587
Query: 422 LTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNN 481
S+ L+L N LE + MF GL L+ L L N I I +F L N++LL L +N
Sbjct: 588 AASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDN 647
Query: 482 LLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLK 541
+ ++ G D L + ++L NP++C C + L
Sbjct: 648 QITTVSP------------------------GAFDTLQSLSTLNLLANPFNCNCQLAWLG 683
Query: 542 DWTEHANSPVIINEVTCESP 561
W ++ C++P
Sbjct: 684 GWLR--KRKIVTGNPRCQNP 701
Score = 88.6 bits (218), Expect = 2e-17
Identities = 106/426 (24%), Positives = 167/426 (39%), Gaps = 67/426 (15%)
Query: 18 QTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRL 77
Q S + +C +C CE NV + C + T + P +L LN N ++ L
Sbjct: 502 QLNSECNSDVVCPHKCRCEA--NV--VECSSLKLTKIPERIPQSTA--ELRLNNNEISIL 555
Query: 78 YPNE-FVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESL 136
F ++ ++L NN + EI GAF G ++ LHL N+LE +R F GL+ L
Sbjct: 556 EATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGL 615
Query: 137 EYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVM 196
L N IS I +F+ L +++L L DN + ++
Sbjct: 616 RTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVS---------------------- 653
Query: 197 PFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQ 256
G + + + + L NP+NC C L L WL + G C+ P L Q
Sbjct: 654 --PGAFDTLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPDFLR-----Q 706
Query: 257 LTRQDLC-PRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPKASRPPKMRNRPTPR- 314
+ QD+ P + + G + R A T +++ + + P+
Sbjct: 707 IPLQDVAFPDFRCEEGQEEGG----CLPRPQCPQECACLDTVVRCSNKHLRALPKGIPKN 762
Query: 315 -VTVSKDRQSF----GPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISD 369
+ D F G + ++ V L S+N ++ + FTN+S
Sbjct: 763 VTELYLDGNQFTLVPGQLSTFKYLQLVDL------------SNNKIS-SLSNSSFTNMSQ 809
Query: 370 LQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLY 429
L L L+ N LQ + SL LL L N I+ +QEG F ++TSL L
Sbjct: 810 L-------TTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLA 862
Query: 430 LNGNYL 435
+ N L
Sbjct: 863 IGANPL 868
Score = 70.1 bits (170), Expect = 8e-12
Identities = 86/354 (24%), Positives = 144/354 (40%), Gaps = 29/354 (8%)
Query: 134 ESLEYLQADYNYISAIEA-GAFSKLNKLKVLILNDNLLLSLPSNVFRFVL-LTHLDLRGN 191
+S L+ + N IS +EA G F KL LK + L++N + + F ++ L L N
Sbjct: 540 QSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTAN 599
Query: 192 RLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHG 251
+L+ + +G+ + G+ + L N +C + D+ T + L+
Sbjct: 600 QLESIR-SGMFRGLDGLRTLMLRNNRISCIHN--------DSFTGLRNVRLLS----LYD 646
Query: 252 KDVTQLTRQDLCPRKSASDSSQRGSHADTHVQR--LSPTMNPALNPTRAPKASRPPKMRN 309
+T ++ +S S + + + + Q L + T P+ P +R
Sbjct: 647 NQITTVSPGAFDTLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPDFLRQ 706
Query: 310 RPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISD 369
P V R G P CP C C V C + +
Sbjct: 707 IPLQDVAFPDFRCEEGQEEGGCLPRP---QCPQECACLDTV------VRCSNKHLRALPK 757
Query: 370 LQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLY 429
PK + +LYL GN T+ L + L L+ L NN+I+ + +FTN++ L L
Sbjct: 758 GIPKNVT--ELYLDGNQF-TLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLI 814
Query: 430 LNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLL 483
L+ N L+ + P F GL+SL+ L L N I ++ F + +L L + N L
Sbjct: 815 LSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPL 868
Score = 50.4 bits (119), Expect = 7e-06
Identities = 45/167 (26%), Positives = 65/167 (38%), Gaps = 27/167 (16%)
Query: 87 NAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYI 146
N L+L N + G S K L+ + L+NNK+ L +F + L L YN +
Sbjct: 762 NVTELYLDGNQFTLV-PGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNAL 820
Query: 147 SAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVL-LTHLDLRGNRLKVMPFAGVLEHI 205
I AF L L++L L+ N + +L +F V L+HL
Sbjct: 821 QCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHL------------------- 861
Query: 206 GGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGK 252
+ NP C C L L +W+ T G C P + GK
Sbjct: 862 ------AIGANPLYCDCHLRWLSSWVKTGYKEPGIARCAGPQDMEGK 902
>gi|4759146 slit homolog 2 [Homo sapiens]
Length = 1529
Score = 134 bits (336), Expect = 5e-31
Identities = 145/567 (25%), Positives = 214/567 (37%), Gaps = 102/567 (17%)
Query: 2 LSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQ 61
+ GV + + G++ K A C +C C ++C +V P
Sbjct: 1 MRGVGWQMLSLSLGLVLAILNKVAPQACPAQCSCSGS----TVDCHGLALRSVPRNIPRN 56
Query: 62 YRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNK 121
+L LNGN +TR+ +F + L L N + I GAF LK L+RL LN N
Sbjct: 57 TE--RLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNH 114
Query: 122 LEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFV 181
L++ E FLG L L N I AI AF +K L L+ N + + FR +
Sbjct: 115 LQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRAL 174
Query: 182 L-LTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
L L L N + + A H+ + +L N C C L AWL
Sbjct: 175 RDLEVLTLNNNNITRLSVAS-FNHMPKLRTFRLHSNNLYCDCHL----AWL--------- 220
Query: 241 IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPK 300
SD ++ + Q + P+ N K
Sbjct: 221 ----------------------------SDWLRQRPRVGLYTQCMGPSHLRGHNVAEVQK 252
Query: 301 ASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQ 360
R V QSF S L CP++C C++ V+C+
Sbjct: 253 -------------REFVCSGHQSF------MAPSCSVLHCPAACTCSNNI------VDCR 287
Query: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFT 420
+ T I P+ + ++ L N ++ + Y L + L NN+I+ + AF
Sbjct: 288 GKGLTEIPTNLPETIT--EIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQ 345
Query: 421 NLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNN 480
L SL L L GN + L S+F+GL SLQ L L N I ++ F L NL LL L +
Sbjct: 346 GLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYD 405
Query: 481 NLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGL 540
N L+++ KG L A + L +NP+ C C + L
Sbjct: 406 NKLQTI------------------------AKGTFSPLRAIQTMHLAQNPFICDCHLKWL 441
Query: 541 KDWTEHANSPVIINEVTCESPAKHAGE 567
D+ H N P+ + C SP + A +
Sbjct: 442 ADYL-HTN-PIETSGARCTSPRRLANK 466
Score = 100 bits (250), Expect = 4e-21
Identities = 110/434 (25%), Positives = 168/434 (38%), Gaps = 47/434 (10%)
Query: 29 CKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNA 88
C C C N+ ++C KG T + P I ++ L N + + P F Y
Sbjct: 273 CPAACTCSN--NI--VDCRGKGLTEIPTNLPET--ITEIRLEQNTIKVIPPGAFSPYKKL 326
Query: 89 VTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISA 148
+ L NN + E+ AF GL++L L L NK+ L + F GL SL+ L + N I+
Sbjct: 327 RRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINC 386
Query: 149 IEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHIGGI 208
+ AF L+ L +L L DN L ++ G + I
Sbjct: 387 LRVDAFQDLHNLNLLSLYDNKLQTIAK------------------------GTFSPLRAI 422
Query: 209 MEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDLCPRKSA 268
+ L +NP+ C C L L +L T + C +P RL K + Q+ +
Sbjct: 423 QTMHLAQNPFICDCHLKWLADYLHTNPIETSGARCTSPRRLANKRIGQIKSKKF------ 476
Query: 269 SDSSQRGSHADTHVQRLSPTMNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSFGPIM 328
R S + + + L+ + P K R T V S + + P
Sbjct: 477 -----RCSAKEQYFIPGTEDYRSKLSGDCFADLACPEKCRCEGT-TVDCSNQKLNKIPEH 530
Query: 329 VYQTKSPVPLTCPSSCVCTSQSSDNGL----NVNCQERKFTNISDLQPKPTS-PKKLYLT 383
+ Q + + L V + L +N K T+I + + S ++ LT
Sbjct: 531 IPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLT 590
Query: 384 GNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMF 443
N L+ V SL L L +NRI + +F L+S+R L L N + + P F
Sbjct: 591 SNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAF 650
Query: 444 DGLQSLQYLYLEYN 457
D L SL L L N
Sbjct: 651 DTLHSLSTLNLLAN 664
Score = 93.2 bits (230), Expect = 9e-19
Identities = 100/442 (22%), Positives = 183/442 (41%), Gaps = 61/442 (13%)
Query: 134 ESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVL-LTHLDLRGNR 192
E++ ++ + N I I GAFS KL+ + L++N + L + F+ + L L L GN+
Sbjct: 300 ETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNK 359
Query: 193 LKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGK 252
+ +P + E + + + L N NC L + A+ D + + L+
Sbjct: 360 ITELP-KSLFEGLFSLQLLLLNANKINC----LRVDAFQDLHNLNL--------LSLYDN 406
Query: 253 DVTQLTRQDLCPRKSASDS--SQRGSHADTHVQRLSPTMNPALNPTRAPKASRPPKMRNR 310
+ + + P ++ +Q D H++ L+ ++ T + + P ++ N+
Sbjct: 407 KLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNPIETSGARCTSPRRLANK 466
Query: 311 PTPRVTVSKDR-----QSFGP-IMVYQTKSP----VPLTCPSSCVCTSQSSDNGLNVNCQ 360
++ K R Q F P Y++K L CP C C G V+C
Sbjct: 467 RIGQIKSKKFRCSAKEQYFIPGTEDYRSKLSGDCFADLACPEKCRC------EGTTVDCS 520
Query: 361 ERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLE-YSSLDLLHLGNNRIAVIQEGAF 419
+K I + P+ T+ +L L N + + + L ++ NN+I I+EGAF
Sbjct: 521 NQKLNKIPEHIPQYTA--ELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAF 578
Query: 420 TNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLN 479
+ + + L N LE + MF GL+SL+ L L N I + +F L +++LL L
Sbjct: 579 EGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLY 638
Query: 480 NNLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMG 539
+N + ++ G D L + ++L NP++C C +
Sbjct: 639 DNQITTV------------------------APGAFDTLHSLSTLNLLANPFNCNCYLAW 674
Query: 540 LKDWTEHANSPVIINEVTCESP 561
L +W ++ C+ P
Sbjct: 675 LGEWLR--KKRIVTGNPRCQKP 694
Score = 90.5 bits (223), Expect = 6e-18
Identities = 80/295 (27%), Positives = 124/295 (42%), Gaps = 25/295 (8%)
Query: 337 PLTCPSSCVCTSQSSD-NGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDL 395
P CP+ C C+ + D +GL + R P + ++L L GN + + K D
Sbjct: 25 PQACPAQCSCSGSTVDCHGLALRSVPRNI---------PRNTERLDLNGNNITRITKTDF 75
Query: 396 LEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLE 455
L +L L N+I+ I+ GAF +L L RL LN N+L++ +F G L L L
Sbjct: 76 AGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLS 135
Query: 456 YNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTA-LTRLNLRNNHFSHLPVKGV 514
N I+ I F ++++ L L+ N + + D F L L L NN+ + L V
Sbjct: 136 ENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVAS- 194
Query: 515 LDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVTCESPAKHAG-EILKFLG 573
+ +P L N C C + L DW P + C P+ G + +
Sbjct: 195 FNHMPKLRTFRLHSNNLYCDCHLAWLSDWLR--QRPRVGLYTQCMGPSHLRGHNVAEVQK 252
Query: 574 REAIC--------PDSPNLSDGTVLSMNHNTDTPR--SLSVSPSSYPELHTEVPL 618
RE +C P L + ++N R L+ P++ PE TE+ L
Sbjct: 253 REFVCSGHQSFMAPSCSVLHCPAACTCSNNIVDCRGKGLTEIPTNLPETITEIRL 307
Score = 83.2 bits (204), Expect = 9e-16
Identities = 94/409 (22%), Positives = 159/409 (38%), Gaps = 55/409 (13%)
Query: 29 CKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNE-FVNYSN 87
C +C CE ++C N+ + PQY +L LN N T L F
Sbjct: 506 CPEKCRCEGT----TVDCSNQKLNKIPE-HIPQYTA-ELRLNNNEFTVLEATGIFKKLPQ 559
Query: 88 AVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYIS 147
++ NN + +I GAF G + + L +N+LE ++ F GLESL+ L N I+
Sbjct: 560 LRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRIT 619
Query: 148 AIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHIGG 207
+ +F L+ +++L L DN + ++ G + +
Sbjct: 620 CVGNDSFIGLSSVRLLSLYDNQITTVA------------------------PGAFDTLHS 655
Query: 208 IMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDL-CPRK 266
+ + L NP+NC C L L WL + G C+ P+ L + + QD C
Sbjct: 656 LSTLNLLANPFNCNCYLAWLGEWLRKKRIVTGNPRCQKPYFLKEIPIQDVAIQDFTCDDG 715
Query: 267 SASDSSQRGSHADTHVQRLSPTMNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSFGP 326
+ +S S T L + + + PK R + + ++ + P
Sbjct: 716 NDDNSCSPLSRCPTECTCLDTVVRCSNKGLKV-----LPKGIPRDVTELYLDGNQFTLVP 770
Query: 327 IMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNY 386
+ K + ++ + T + F+N++ L L L+ N
Sbjct: 771 KELSNYKHLTLIDLSNNRIST-----------LSNQSFSNMTQL-------LTLILSYNR 812
Query: 387 LQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYL 435
L+ + SL LL L N I+V+ EGAF +L++L L + N L
Sbjct: 813 LRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPL 861
Score = 75.5 bits (184), Expect = 2e-13
Identities = 95/377 (25%), Positives = 149/377 (39%), Gaps = 61/377 (16%)
Query: 115 LHLNNNKLEILRED-TFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSL 173
L LNNN+ +L F L L + N I+ IE GAF + + ++L N L ++
Sbjct: 538 LRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENV 597
Query: 174 PSNVFRFV-LLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLD 232
+F+ + L L LR NR+ + + G+ ++L
Sbjct: 598 QHKMFKGLESLKTLMLRSNRITCVGNDSFI----GLSSVRL------------------- 634
Query: 233 TITVFVGEIVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPA 292
++++ +I P D S + + + ++ L +
Sbjct: 635 -LSLYDNQITTVAPGAF-----------DTLHSLSTLNLLANPFNCNCYLAWLGEWLRKK 682
Query: 293 LNPTRAPKASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLT-CPSSCVCTS--- 348
T P+ +P ++ P V + Q F S PL+ CP+ C C
Sbjct: 683 RIVTGNPRCQKPYFLKEIPIQDVAI----QDFTCDDGNDDNSCSPLSRCPTECTCLDTVV 738
Query: 349 QSSDNGLNVNCQERKFTNISDLQPK--PTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHL 406
+ S+ GL V PK P +LYL GN V K +L Y L L+ L
Sbjct: 739 RCSNKGLKV-------------LPKGIPRDVTELYLDGNQFTLVPK-ELSNYKHLTLIDL 784
Query: 407 GNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLT 466
NNRI+ + +F+N+T L L L+ N L + P FDGL+SL+ L L N I +
Sbjct: 785 SNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGA 844
Query: 467 FDALINLQLLFLNNNLL 483
F+ L L L + N L
Sbjct: 845 FNDLSALSHLAIGANPL 861
Score = 58.9 bits (141), Expect = 2e-08
Identities = 50/176 (28%), Positives = 79/176 (44%), Gaps = 11/176 (6%)
Query: 397 EYSSLD-LLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLE 455
E + LD ++ N + V+ +G ++T L YL+GN L P + L + L
Sbjct: 730 ECTCLDTVVRCSNKGLKVLPKGIPRDVTEL---YLDGNQF-TLVPKELSNYKHLTLIDLS 785
Query: 456 YNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGT-ALTRLNLRNNHFSHLPVKGV 514
N I + +F + L L L+ N LR +P F G +L L+L N S +P +G
Sbjct: 786 NNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVP-EGA 844
Query: 515 LDQLPAFIQIDLQENPWDCTCDIMGLKDWTE-HANSPVIINEVTCESPAKHAGEIL 569
+ L A + + NP C C++ L DW + P I C P + A ++L
Sbjct: 845 FNDLSALSHLAIGANPLYCDCNMQWLSDWVKSEYKEPGI---ARCAGPGEMADKLL 897
Score = 49.3 bits (116), Expect = 1e-05
Identities = 50/224 (22%), Positives = 77/224 (34%), Gaps = 55/224 (24%)
Query: 29 CKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNA 88
C C C + + C NKG + P + +L+L+GN T L P E NY
Sbjct: 727 CPTECTCLDTV----VRCSNKGLKVLPKGIPRD--VTELYLDGNQFT-LVPKELSNY--- 776
Query: 89 VTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISA 148
K L + L+NN++ L +F + L L YN +
Sbjct: 777 ---------------------KHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRC 815
Query: 149 IEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHIGGI 208
I F L L++L L GN + V+P G + +
Sbjct: 816 IPPRTFDGLKSLRLL-----------------------SLHGNDISVVP-EGAFNDLSAL 851
Query: 209 MEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGK 252
+ + NP C C++ L W+ + G C P + K
Sbjct: 852 SHLAIGANPLYCDCNMQWLSDWVKSEYKEPGIARCAGPGEMADK 895
>gi|11321571 slit homolog 3 [Homo sapiens]
Length = 1523
Score = 132 bits (333), Expect = 1e-30
Identities = 136/564 (24%), Positives = 211/564 (37%), Gaps = 149/564 (26%)
Query: 29 CKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNA 88
C +C C + +++C G V P +L L+ N +TR+ +F N
Sbjct: 34 CPTKCTC----SAASVDCHGLGLRAVPRGIPRNAE--RLDLDRNNITRITKMDFAGLKNL 87
Query: 89 VTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILRE--------------------- 127
LHL +N + I GAF LK L+RL LN NKL++L E
Sbjct: 88 RVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQG 147
Query: 128 ---DTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLT 184
F G+ ++ LQ D N+IS IE GAF L L++L LN+N N+ R ++ +
Sbjct: 148 IPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNN-------NISRILVTS 200
Query: 185 HLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCE 244
H+ I ++L N C C L L WL +C
Sbjct: 201 -----------------FNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRTVGQFTLCM 243
Query: 245 TPFRLHGKDVTQLTRQD-LCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPKASR 303
P L G +V + +++ +CP AP +
Sbjct: 244 APVHLRGFNVADVQKKEYVCP---------------------------------APHSEP 270
Query: 304 PPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERK 363
P N P P TC ++ V+C+ +
Sbjct: 271 PSCNAN---------------------SISCPSPCTCSNNI------------VDCRGKG 297
Query: 364 FTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLT 423
I P ++ L N ++ + +Y L + + N+I+ I AF L
Sbjct: 298 LMEIP--ANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLK 355
Query: 424 SLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLL 483
SL L L GN + + +FDGL SLQ L L N I ++ TF L NL LL L +N L
Sbjct: 356 SLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKL 415
Query: 484 RSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDW 543
+++ KG+ L + + L +NP+ C C + L D+
Sbjct: 416 QTIS------------------------KGLFAPLQSIQTLHLAQNPFVCDCHLKWLADY 451
Query: 544 TEHANSPVIINEVTCESPAKHAGE 567
+ ++P+ + C SP + A +
Sbjct: 452 LQ--DNPIETSGARCSSPRRLANK 473
Score = 97.8 bits (242), Expect = 4e-20
Identities = 101/434 (23%), Positives = 183/434 (42%), Gaps = 53/434 (12%)
Query: 134 ESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVL-LTHLDLRGNR 192
E + ++ + N I AI AGAF++ KLK + ++ N + + + F+ + LT L L GN+
Sbjct: 307 EGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNK 366
Query: 193 LKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGK 252
+ + G+ + + + + L N NC L + + D + + L+
Sbjct: 367 ITEIA-KGLFDGLVSLQLLLLNANKINC----LRVNTFQDLQNLNL--------LSLYDN 413
Query: 253 DVTQLTRQDLCPRKSASDS--SQRGSHADTHVQRLSPTMNPALNPTRAPKASRPPKMRNR 310
+ +++ P +S +Q D H++ L+ + T + S P ++ N+
Sbjct: 414 KLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRRLANK 473
Query: 311 PTPRVTVSKDRQSFGPIMVYQTKSP--VPLTCPSSCVCTSQSSDNGLNVNCQERKFTNIS 368
++ K R S + S + L CP C C G V+C +K I
Sbjct: 474 RISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCRC------EGTIVDCSNQKLVRIP 527
Query: 369 DLQPKPTSPKKLYLTGNYLQTVYKNDLLE-YSSLDLLHLGNNRIAVIQEGAFTNLTSLRR 427
P+ + L L N + + + + +L ++L NN+I ++EGAF S++
Sbjct: 528 SHLPEYVTD--LRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQE 585
Query: 428 LYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLP 487
L L GN LE ++ +F GL L+ L L N+I + TF L +++LL L +N + ++
Sbjct: 586 LMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTIT 645
Query: 488 DNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHA 547
F T L L+ I+L NP++C C + L W
Sbjct: 646 PGAF--TTLVSLST----------------------INLLSNPFNCNCHLAWLGKWLRKR 681
Query: 548 NSPVIINEVTCESP 561
++ C+ P
Sbjct: 682 R--IVSGNPRCQKP 693
Score = 95.9 bits (237), Expect = 1e-19
Identities = 72/249 (28%), Positives = 114/249 (45%), Gaps = 17/249 (6%)
Query: 335 PVPLTCPSSCVCTSQSSD-NGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKN 393
P + CP+ C C++ S D +GL + R P + ++L L N + + K
Sbjct: 29 PPAVACPTKCTCSAASVDCHGLGLRAVPRGI---------PRNAERLDLDRNNITRITKM 79
Query: 394 DLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLY 453
D +L +LHL +N+++VI+ GAF +L L RL LN N L+VL +F L L
Sbjct: 80 DFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLD 139
Query: 454 LEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTA-LTRLNLRNNHFSHLPVK 512
L N I+ I F + +++ L L+NN + + D F L L L NN+ S + V
Sbjct: 140 LSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVT 199
Query: 513 GVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVT-CESPAKHAG-EILK 570
+ +P + L N C C + L DW + + + T C +P G +
Sbjct: 200 S-FNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRT---VGQFTLCMAPVHLRGFNVAD 255
Query: 571 FLGREAICP 579
+E +CP
Sbjct: 256 VQKKEYVCP 264
Score = 89.0 bits (219), Expect = 2e-17
Identities = 101/436 (23%), Positives = 162/436 (37%), Gaps = 59/436 (13%)
Query: 29 CKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNA 88
C C C N+ ++C KG + P I ++ L N + + F Y
Sbjct: 280 CPSPCTCSN--NI--VDCRGKGLMEIPANLPEG--IVEIRLEQNSIKAIPAGAFTQYKKL 333
Query: 89 VTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISA 148
+ + N + +I AF GLK+L L L NK+ + + F GL SL+ L + N I+
Sbjct: 334 KRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINC 393
Query: 149 IEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHIGGI 208
+ F L L +L L DN L ++ G+ + I
Sbjct: 394 LRVNTFQDLQNLNLLSLYDNKLQTISK------------------------GLFAPLQSI 429
Query: 209 MEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDLCPRKSA 268
+ L +NP+ C C L L +L + C +P RL K ++Q+ + R S
Sbjct: 430 QTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRRLANKRISQIKSKKF--RCSG 487
Query: 269 SDSSQRGSHADTHVQRLSPTMNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSFGPIM 328
S+ + ++ + + P K R T V Q I
Sbjct: 488 SEDYRSRFSSECFMDLVC-----------------PEKCRCEGT---IVDCSNQKLVRIP 527
Query: 329 VYQTKSPVPLTCPSSCVCTSQSS------DNGLNVNCQERKFTNISD-LQPKPTSPKKLY 381
+ + L + V +++ N +N K + + S ++L
Sbjct: 528 SHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELM 587
Query: 382 LTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPS 441
LTGN L+TV+ S L L L +N I + F L+S+R L L N + + P
Sbjct: 588 LTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPG 647
Query: 442 MFDGLQSLQYLYLEYN 457
F L SL + L N
Sbjct: 648 AFTTLVSLSTINLLSN 663
Score = 86.7 bits (213), Expect = 8e-17
Identities = 98/409 (23%), Positives = 158/409 (38%), Gaps = 54/409 (13%)
Query: 28 ICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNE-FVNYS 86
+C +C CE ++C N+ + P+Y + L LN N ++ L F
Sbjct: 504 VCPEKCRCEGTI----VDCSNQKLVRIPS-HLPEY-VTDLRLNDNEVSVLEATGIFKKLP 557
Query: 87 NAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYI 146
N ++L NN ++E+R GAF G +++ L L N+LE + F GL L+ L N I
Sbjct: 558 NLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLI 617
Query: 147 SAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHIG 206
+ F+ L+ +++L L DN + ++ F ++
Sbjct: 618 GCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLV------------------------ 653
Query: 207 GIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDLCPRK 266
+ I L NP+NC C L L WL + G C+ PF L + + QD
Sbjct: 654 SLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQKPFFLKEIPIQDVAIQDFTCDG 713
Query: 267 SASDSSQRGSHADTHVQRLSPTMNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSFGP 326
+ S Q + + + RA P KD
Sbjct: 714 NEESSCQLSPRCPEQCTCMETVVRCSNKGLRALPRGMP--------------KDVTELYL 759
Query: 327 IMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNY 386
+ T P L+ + S+N +++ F+N+S L L L+ N
Sbjct: 760 EGNHLTAVPRELSALRH-LTLIDLSNNSISM-LTNYTFSNMSHL-------STLILSYNR 810
Query: 387 LQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYL 435
L+ + + SL +L L N I+ + EG+F +LTSL L L N L
Sbjct: 811 LRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPL 859
Score = 70.9 bits (172), Expect = 5e-12
Identities = 85/349 (24%), Positives = 144/349 (41%), Gaps = 30/349 (8%)
Query: 139 LQADYNYISAIEA-GAFSKLNKLKVLILNDNLLLSLPSNVFRFVL-LTHLDLRGNRLKVM 196
L+ + N +S +EA G F KL L+ + L++N + + F + L L GN+L+ +
Sbjct: 537 LRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETV 596
Query: 197 PFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQ 256
V + G+ + L N C + DT F G + L+ +T
Sbjct: 597 -HGRVFRGLSGLKTLMLRSNLIGCVSN--------DT---FAG-LSSVRLLSLYDNRITT 643
Query: 257 LTRQDLCPRKSASDSSQRGS--HADTHVQRLSPTMNPALNPTRAPKASRPPKMRNRPTPR 314
+T S S + + + + H+ L + + P+ +P ++ P
Sbjct: 644 ITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQKPFFLKEIPIQD 703
Query: 315 VTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKP 374
V + Q F ++ + CP C C V C + + PK
Sbjct: 704 VAI----QDFTCDGNEESSCQLSPRCPEQCTCMETV------VRCSNKGLRALPRGMPKD 753
Query: 375 TSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNY 434
+ +LYL GN+L T +L L L+ L NN I+++ F+N++ L L L+ N
Sbjct: 754 VT--ELYLEGNHL-TAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNR 810
Query: 435 LEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLL 483
L + F+GL+SL+ L L N I + +F+ L +L L L N L
Sbjct: 811 LRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPL 859
Score = 56.2 bits (134), Expect = 1e-07
Identities = 53/218 (24%), Positives = 78/218 (35%), Gaps = 55/218 (25%)
Query: 29 CKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNA 88
C +C C E + C NKG + P + +L+L GN LT + P E
Sbjct: 725 CPEQCTCMETV----VRCSNKGLRALPRGMPKD--VTELYLEGNHLTAV-PREL------ 771
Query: 89 VTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISA 148
S L+ L + L+NN + +L TF + L L YN +
Sbjct: 772 ------------------SALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRC 813
Query: 149 IEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHIGGI 208
I AF+ L L+VL L+ N + S+P F + +
Sbjct: 814 IPVHAFNGLRSLRVLTLHGNDISSVPEGSFN------------------------DLTSL 849
Query: 209 MEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETP 246
+ L NP +C C L L W+ G C +P
Sbjct: 850 SHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSP 887
>gi|194440719 chondroadherin-like [Homo sapiens]
Length = 762
Score = 125 bits (314), Expect = 2e-28
Identities = 135/519 (26%), Positives = 196/519 (37%), Gaps = 106/519 (20%)
Query: 66 QLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEIL 125
+L L GN L L P F TL+L +N L + AF GL ++ L L++N L +L
Sbjct: 138 RLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVL 197
Query: 126 REDTFLGLESLEYLQADYNYISAIEAGAFSK------------------------LNKLK 161
+ GL +L L +N + A+ S+ L L+
Sbjct: 198 APEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALPGLR 257
Query: 162 VLILNDNLLLSLPSNVFRFVLLTH-LDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNC 220
L+L+ L +L F H LDLRGN+L +P L+ G + ++L+ NP C
Sbjct: 258 ELLLDGGALQALGPRAFAHCPRLHTLDLRGNQLDTLP---PLQGPGQLRRLRLQGNPLWC 314
Query: 221 TCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDL-CPRKSASDSSQRGSHAD 279
C PL WL V + C+ P RL G+ + L DL CP +A + + A
Sbjct: 315 GCQARPLLEWLARARV-RSDGACQGPRRLRGEALDALRPWDLRCPGDAAQEEEELEERA- 372
Query: 280 THVQRLSPTMNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLT 339
++ P P R P R
Sbjct: 373 -----VAGPRAPPRGPPRGPGEER--------------------------------AVAP 395
Query: 340 CPSSCVCTSQ---SSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLL 396
CP +CVC + SS G + R F P+ + L L N+ +V +
Sbjct: 396 CPRACVCVPESRHSSCEGCGLQAVPRGF---------PSDTQLLDLRRNHFPSVPRAAFP 446
Query: 397 EYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEY 456
L LHL + IA ++ GA L L LYL+ N L L + +G L YLYLE
Sbjct: 447 GLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYLER 506
Query: 457 NVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGT---------------------- 494
N ++ AL +L L L +N + L G T
Sbjct: 507 NRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSLGALG 566
Query: 495 ---ALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENP 530
L +L+L N +P G L+ LPA +++ L NP
Sbjct: 567 PARELEKLHLDRNQLREVPT-GALEGLPALLELQLSGNP 604
Score = 82.0 bits (201), Expect = 2e-15
Identities = 59/194 (30%), Positives = 93/194 (47%), Gaps = 7/194 (3%)
Query: 64 IYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLE 123
++ L L N + RL P + ++L N + E+ GA + L++LHL+ N+L
Sbjct: 523 LFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSLGALGPARELEKLHLDRNQLR 582
Query: 124 ILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNK-LKVLILNDNLLLSLPSNVFRFV- 181
+ GL +L LQ N + A+ GAF + + L+ L LN + L + F +
Sbjct: 583 EVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQHLFLNSSGLEQICPGAFSGLG 642
Query: 182 -LLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGE 240
L L L+ N+L+ +P L + + I L NP++C C LLPL WL + + VG
Sbjct: 643 PGLQSLHLQKNQLRALP---ALPSLSQLELIDLSSNPFHCDCQLLPLHRWLTGLNLRVG- 698
Query: 241 IVCETPFRLHGKDV 254
C TP G+ V
Sbjct: 699 ATCATPPNARGQRV 712
Score = 80.5 bits (197), Expect = 6e-15
Identities = 65/191 (34%), Positives = 92/191 (48%), Gaps = 8/191 (4%)
Query: 340 CPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYS 399
CP +C+C + +V C+ + T + D P+ T ++L L GN L+ +
Sbjct: 33 CPQACICDNSRR----HVACRYQNLTEVPDAIPELT--QRLDLQGNLLKVIPAAAFQGVP 86
Query: 400 SLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVI 459
L L L + + ++ EGAF L L L L N+L L DGL SL+ L LE N +
Sbjct: 87 HLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQEALDGLGSLRRLELEGNAL 146
Query: 460 KEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTR-LNLRNNHFSHLPVKGVLDQL 518
+E++P TF AL L L L +N L LP F G R L L +N S L + L L
Sbjct: 147 EELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPE-ALAGL 205
Query: 519 PAFIQIDLQEN 529
PA ++ L N
Sbjct: 206 PALRRLSLHHN 216
Score = 66.2 bits (160), Expect = 1e-10
Identities = 61/227 (26%), Positives = 95/227 (41%), Gaps = 30/227 (13%)
Query: 16 ILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLT 75
+L +R+ A C C+C+ ++ C + T V P + +L L GNLL
Sbjct: 20 LLLAPARQAAAQRCPQACICDNSRR--HVACRYQNLTEVPDAIPELTQ--RLDLQGNLLK 75
Query: 76 RLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLES 135
+ F + L L + ++ + GAF GL L L+L +N L L ++ GL S
Sbjct: 76 VIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQEALDGLGS 135
Query: 136 LEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVF------RFVLLTH---- 185
L L+ + N + + G F L L L L N L+ LP+ F R++ L+H
Sbjct: 136 LRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALS 195
Query: 186 ---------------LDLRGNRLKVMPFAGVLEHIGGIMEIQLEENP 217
L L N L+ +P VL G+ ++L NP
Sbjct: 196 VLAPEALAGLPALRRLSLHHNELQALP-GPVLSQARGLARLELGHNP 241
Score = 65.9 bits (159), Expect = 2e-10
Identities = 63/230 (27%), Positives = 90/230 (39%), Gaps = 35/230 (15%)
Query: 380 LYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLY 439
LYL N V L SL LHL +N + + G +LR +YL+GN + +
Sbjct: 502 LYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVS 561
Query: 440 PSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFG------- 492
+ L+ L+L+ N ++E+ + L L L L+ N LR+L D F
Sbjct: 562 LGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQ 621
Query: 493 --------------------GTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWD 532
G L L+L+ N LP L QL IDL NP+
Sbjct: 622 HLFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLRALPALPSLSQLEL---IDLSSNPFH 678
Query: 533 CTCDIMGLKDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSP 582
C C ++ L W N V TC +P G+ +K A+ D P
Sbjct: 679 CDCQLLPLHRWLTGLNLRV---GATCATPPNARGQRVK--AAAAVFEDCP 723
Score = 62.0 bits (149), Expect = 2e-09
Identities = 62/222 (27%), Positives = 93/222 (41%), Gaps = 31/222 (13%)
Query: 376 SPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYL 435
S ++L L GN L+ + +L L+L +N + + AF L +R L L+ N L
Sbjct: 135 SLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNAL 194
Query: 436 EVLYPSMFDGLQSLQYLYLEYNVIKEI------------------KPLTFD------ALI 471
VL P GL +L+ L L +N ++ + PLT+ AL
Sbjct: 195 SVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALP 254
Query: 472 NLQLLFLNNNLLRSLPDNIFGGTA-LTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENP 530
L+ L L+ L++L F L L+LR N LP QL ++ LQ NP
Sbjct: 255 GLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQLDTLPPLQGPGQLR---RLRLQGNP 311
Query: 531 WDCTCDIMGLKDWTEHANSPVIINEVTCESPAKHAGEILKFL 572
C C L +W A + ++ C+ P + GE L L
Sbjct: 312 LWCGCQARPLLEWLARAR---VRSDGACQGPRRLRGEALDAL 350
>gi|13194201 reticulon 4 receptor precursor [Homo sapiens]
Length = 473
Score = 105 bits (263), Expect = 1e-22
Identities = 75/214 (35%), Positives = 107/214 (50%), Gaps = 10/214 (4%)
Query: 51 FTTVSLLQPPQYRIYQLFLNGNLLTR-LYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGL 109
FT ++LL+ QL L+ N R + P F TLHL GLQE+ G F GL
Sbjct: 101 FTGLALLE-------QLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGL 153
Query: 110 KTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNL 169
L+ L+L +N L+ L +DTF L +L +L N IS++ AF L+ L L+L+ N
Sbjct: 154 AALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNR 213
Query: 170 LLSLPSNVFRFV-LLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLK 228
+ + + FR + L L L N L +P L + + ++L +NPW C C PL
Sbjct: 214 VAHVHPHAFRDLGRLMTLYLFANNLSALP-TEALAPLRALQYLRLNDNPWVCDCRARPLW 272
Query: 229 AWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDL 262
AWL E+ C P RL G+D+ +L DL
Sbjct: 273 AWLQKFRGSSSEVPCSLPQRLAGRDLKRLAANDL 306
Score = 89.0 bits (219), Expect = 2e-17
Identities = 80/287 (27%), Positives = 119/287 (41%), Gaps = 58/287 (20%)
Query: 336 VPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDL 395
V CP +CVC ++ + +C ++ + P + ++++L GN + V
Sbjct: 23 VAAPCPGACVCYNEPK---VTTSCPQQGLQAVP--VGIPAASQRIFLHGNRISHVPAASF 77
Query: 396 LEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNY--------------------- 434
+L +L L +N +A I AFT L L +L L+ N
Sbjct: 78 RACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATFHGLGRLHTLHL 137
Query: 435 ----LEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNI 490
L+ L P +F GL +LQYLYL+ N ++ + TF L NL LFL+ N + S+P+
Sbjct: 138 DRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRISSVPERA 197
Query: 491 FGGT-ALTRLNLRNNHFSH------------------------LPVKGVLDQLPAFIQID 525
F G +L RL L N +H LP + L L A +
Sbjct: 198 FRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTE-ALAPLRALQYLR 256
Query: 526 LQENPWDCTCDIMGLKDWTEHANSPVIINEVTCESPAKHAGEILKFL 572
L +NPW C C L W + +EV C P + AG LK L
Sbjct: 257 LNDNPWVCDCRARPLWAWLQKFRGS--SSEVPCSLPQRLAGRDLKRL 301
>gi|205277468 leucine rich repeat containing 15 isoform a [Homo
sapiens]
Length = 587
Score = 105 bits (262), Expect = 2e-22
Identities = 72/238 (30%), Positives = 116/238 (48%), Gaps = 43/238 (18%)
Query: 54 VSLLQPP----QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGL 109
+ LL P + + +L+L+ N +++L P+ F+ L L N L+E+ G F +
Sbjct: 239 IGLLSPGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPM 298
Query: 110 KTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNL 169
L+ L L +N + L ++ F L L+ L N IS I GAF+ L +L+ L L+ N
Sbjct: 299 PNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNA 358
Query: 170 LLSLPSNVFRFVL-LTHLDLRGNRLKVMP---FA--------------------GVLEHI 205
L L NVFR + L ++ L+ NRL+ +P FA G+ +H+
Sbjct: 359 LQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLPLGIFDHL 418
Query: 206 GGIMEIQLEENPWNCTCDLLPLKAWL---------DTITVFVGEIVCETPFRLHGKDV 254
G + E++L +NPW C D+LPL+ WL DT+ VC +P + G+ +
Sbjct: 419 GKLCELRLYDNPWRCDSDILPLRNWLLLNQPRLGTDTVP------VCFSPANVRGQSL 470
Score = 102 bits (253), Expect = 2e-21
Identities = 67/204 (32%), Positives = 102/204 (50%), Gaps = 5/204 (2%)
Query: 379 KLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVL 438
+L L GN L+ + +L L L +N I+ + + F+NL L+ L L+ N + +
Sbjct: 279 RLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFI 338
Query: 439 YPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGG-TALT 497
P F+GL L+ L L N ++++ F L NLQ + L NN LR LP NIF L
Sbjct: 339 SPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLM 398
Query: 498 RLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEV- 556
+ L+NN +LP+ G+ D L ++ L +NPW C DI+ L++W N P + +
Sbjct: 399 AIQLQNNQLENLPL-GIFDHLGKLCELRLYDNPWRCDSDILPLRNWL-LLNQPRLGTDTV 456
Query: 557 -TCESPAKHAGEILKFLGREAICP 579
C SPA G+ L + P
Sbjct: 457 PVCFSPANVRGQSLIIINVNVAVP 480
Score = 88.6 bits (218), Expect = 2e-17
Identities = 58/171 (33%), Positives = 84/171 (49%), Gaps = 8/171 (4%)
Query: 340 CPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYS 399
CPS C C+ S V C + + P P + L + ++ + ++ L S
Sbjct: 31 CPSECTCSRASQ-----VECTGARIVAVPT--PLPWNAMSLQILNTHITELNESPFLNIS 83
Query: 400 SLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVI 459
+L L + N ++ I GAF NL SLR L L N L+VL +F GL SL+ L L N +
Sbjct: 84 ALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQL 143
Query: 460 KEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGG-TALTRLNLRNNHFSHL 509
+I+P F NL+ L L+ N L +PD F LT+LNL N +H+
Sbjct: 144 LQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHI 194
Score = 83.6 bits (205), Expect = 7e-16
Identities = 62/189 (32%), Positives = 89/189 (47%), Gaps = 7/189 (3%)
Query: 29 CKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNA 88
C C C V E G V++ P + L + +T L + F+N S
Sbjct: 31 CPSECTCSRASQV-----ECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFLNISAL 85
Query: 89 VTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISA 148
+ L + N L I GAF L +L+ L L NNKL++L F GL+SLE L N +
Sbjct: 86 IALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQ 145
Query: 149 IEAGAFSKLNKLKVLILNDNLLLSLPSNVF-RFVLLTHLDLRGNRLKVMPFAGVLEHIGG 207
I+ FS+ + LK L L+ N L +P F V LT L+L N L + V +H+G
Sbjct: 146 IQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHIS-PRVFQHLGN 204
Query: 208 IMEIQLEEN 216
+ ++L EN
Sbjct: 205 LQVLRLYEN 213
Score = 68.2 bits (165), Expect = 3e-11
Identities = 57/179 (31%), Positives = 76/179 (42%), Gaps = 26/179 (14%)
Query: 376 SPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYL 435
S + L L N LQ + SL+ L L +N++ IQ F+ ++L+ L L+GN+L
Sbjct: 108 SLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHL 167
Query: 436 EVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTA 495
E + FD L L L L N + I P F L NLQ+L L N L +P F G
Sbjct: 168 EYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLV 227
Query: 496 -------------------------LTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQEN 529
L RL L NNH S LP + QLP ++ L N
Sbjct: 228 NLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLP-PSIFMQLPQLNRLTLFGN 285
Score = 65.5 bits (158), Expect = 2e-10
Identities = 48/133 (36%), Positives = 62/133 (46%), Gaps = 1/133 (0%)
Query: 379 KLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVL 438
KL L N L + +L +L L NR+ I G F L +L+ L L N + +L
Sbjct: 183 KLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLL 242
Query: 439 YPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTA-LT 497
P +F +LQ LYL N I ++ P F L L L L N L+ L IFG L
Sbjct: 243 SPGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLR 302
Query: 498 RLNLRNNHFSHLP 510
L L +NH S LP
Sbjct: 303 ELWLYDNHISSLP 315
Score = 62.4 bits (150), Expect = 2e-09
Identities = 49/165 (29%), Positives = 77/165 (46%), Gaps = 6/165 (3%)
Query: 57 LQPPQY----RIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTL 112
+QP + + +L L+GN L + F + L+LG N L I F L L
Sbjct: 146 IQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNL 205
Query: 113 KRLHLNNNKLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLS 172
+ L L N+L + TF GL +L+ L N I + G F + L+ L L++N +
Sbjct: 206 QVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQ 265
Query: 173 LPSNVF-RFVLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEEN 216
LP ++F + L L L GN LK + G+ + + E+ L +N
Sbjct: 266 LPPSIFMQLPQLNRLTLFGNSLKELSL-GIFGPMPNLRELWLYDN 309
Score = 36.6 bits (83), Expect = 0.10
Identities = 36/121 (29%), Positives = 53/121 (43%), Gaps = 3/121 (2%)
Query: 375 TSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNY 434
T ++L L N LQ + N ++L + L NNR+ + F N+ L + L N
Sbjct: 347 TELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQ 406
Query: 435 LEVLYPSMFDGLQSLQYLYLEYNVIK---EIKPLTFDALINLQLLFLNNNLLRSLPDNIF 491
LE L +FD L L L L N + +I PL L+N L + + P N+
Sbjct: 407 LENLPLGIFDHLGKLCELRLYDNPWRCDSDILPLRNWLLLNQPRLGTDTVPVCFSPANVR 466
Query: 492 G 492
G
Sbjct: 467 G 467
>gi|18677767 leucine rich repeat containing 15 isoform b [Homo
sapiens]
Length = 581
Score = 105 bits (262), Expect = 2e-22
Identities = 72/238 (30%), Positives = 116/238 (48%), Gaps = 43/238 (18%)
Query: 54 VSLLQPP----QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGL 109
+ LL P + + +L+L+ N +++L P+ F+ L L N L+E+ G F +
Sbjct: 233 IGLLSPGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPM 292
Query: 110 KTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNL 169
L+ L L +N + L ++ F L L+ L N IS I GAF+ L +L+ L L+ N
Sbjct: 293 PNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNA 352
Query: 170 LLSLPSNVFRFVL-LTHLDLRGNRLKVMP---FA--------------------GVLEHI 205
L L NVFR + L ++ L+ NRL+ +P FA G+ +H+
Sbjct: 353 LQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLPLGIFDHL 412
Query: 206 GGIMEIQLEENPWNCTCDLLPLKAWL---------DTITVFVGEIVCETPFRLHGKDV 254
G + E++L +NPW C D+LPL+ WL DT+ VC +P + G+ +
Sbjct: 413 GKLCELRLYDNPWRCDSDILPLRNWLLLNQPRLGTDTVP------VCFSPANVRGQSL 464
Score = 102 bits (253), Expect = 2e-21
Identities = 67/204 (32%), Positives = 102/204 (50%), Gaps = 5/204 (2%)
Query: 379 KLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVL 438
+L L GN L+ + +L L L +N I+ + + F+NL L+ L L+ N + +
Sbjct: 273 RLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFI 332
Query: 439 YPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGG-TALT 497
P F+GL L+ L L N ++++ F L NLQ + L NN LR LP NIF L
Sbjct: 333 SPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLM 392
Query: 498 RLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEV- 556
+ L+NN +LP+ G+ D L ++ L +NPW C DI+ L++W N P + +
Sbjct: 393 AIQLQNNQLENLPL-GIFDHLGKLCELRLYDNPWRCDSDILPLRNWL-LLNQPRLGTDTV 450
Query: 557 -TCESPAKHAGEILKFLGREAICP 579
C SPA G+ L + P
Sbjct: 451 PVCFSPANVRGQSLIIINVNVAVP 474
Score = 88.6 bits (218), Expect = 2e-17
Identities = 58/171 (33%), Positives = 84/171 (49%), Gaps = 8/171 (4%)
Query: 340 CPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYS 399
CPS C C+ S V C + + P P + L + ++ + ++ L S
Sbjct: 25 CPSECTCSRASQ-----VECTGARIVAVPT--PLPWNAMSLQILNTHITELNESPFLNIS 77
Query: 400 SLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVI 459
+L L + N ++ I GAF NL SLR L L N L+VL +F GL SL+ L L N +
Sbjct: 78 ALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQL 137
Query: 460 KEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGG-TALTRLNLRNNHFSHL 509
+I+P F NL+ L L+ N L +PD F LT+LNL N +H+
Sbjct: 138 LQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHI 188
Score = 83.6 bits (205), Expect = 7e-16
Identities = 62/189 (32%), Positives = 89/189 (47%), Gaps = 7/189 (3%)
Query: 29 CKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNA 88
C C C V E G V++ P + L + +T L + F+N S
Sbjct: 25 CPSECTCSRASQV-----ECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFLNISAL 79
Query: 89 VTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISA 148
+ L + N L I GAF L +L+ L L NNKL++L F GL+SLE L N +
Sbjct: 80 IALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQ 139
Query: 149 IEAGAFSKLNKLKVLILNDNLLLSLPSNVF-RFVLLTHLDLRGNRLKVMPFAGVLEHIGG 207
I+ FS+ + LK L L+ N L +P F V LT L+L N L + V +H+G
Sbjct: 140 IQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHIS-PRVFQHLGN 198
Query: 208 IMEIQLEEN 216
+ ++L EN
Sbjct: 199 LQVLRLYEN 207
Score = 68.2 bits (165), Expect = 3e-11
Identities = 57/179 (31%), Positives = 76/179 (42%), Gaps = 26/179 (14%)
Query: 376 SPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYL 435
S + L L N LQ + SL+ L L +N++ IQ F+ ++L+ L L+GN+L
Sbjct: 102 SLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHL 161
Query: 436 EVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTA 495
E + FD L L L L N + I P F L NLQ+L L N L +P F G
Sbjct: 162 EYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLV 221
Query: 496 -------------------------LTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQEN 529
L RL L NNH S LP + QLP ++ L N
Sbjct: 222 NLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLP-PSIFMQLPQLNRLTLFGN 279
Score = 65.5 bits (158), Expect = 2e-10
Identities = 48/133 (36%), Positives = 62/133 (46%), Gaps = 1/133 (0%)
Query: 379 KLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVL 438
KL L N L + +L +L L NR+ I G F L +L+ L L N + +L
Sbjct: 177 KLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLL 236
Query: 439 YPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTA-LT 497
P +F +LQ LYL N I ++ P F L L L L N L+ L IFG L
Sbjct: 237 SPGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLR 296
Query: 498 RLNLRNNHFSHLP 510
L L +NH S LP
Sbjct: 297 ELWLYDNHISSLP 309
Score = 62.4 bits (150), Expect = 2e-09
Identities = 49/165 (29%), Positives = 77/165 (46%), Gaps = 6/165 (3%)
Query: 57 LQPPQY----RIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTL 112
+QP + + +L L+GN L + F + L+LG N L I F L L
Sbjct: 140 IQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNL 199
Query: 113 KRLHLNNNKLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLS 172
+ L L N+L + TF GL +L+ L N I + G F + L+ L L++N +
Sbjct: 200 QVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQ 259
Query: 173 LPSNVF-RFVLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEEN 216
LP ++F + L L L GN LK + G+ + + E+ L +N
Sbjct: 260 LPPSIFMQLPQLNRLTLFGNSLKELSL-GIFGPMPNLRELWLYDN 303
Score = 36.6 bits (83), Expect = 0.10
Identities = 36/121 (29%), Positives = 53/121 (43%), Gaps = 3/121 (2%)
Query: 375 TSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNY 434
T ++L L N LQ + N ++L + L NNR+ + F N+ L + L N
Sbjct: 341 TELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQ 400
Query: 435 LEVLYPSMFDGLQSLQYLYLEYNVIK---EIKPLTFDALINLQLLFLNNNLLRSLPDNIF 491
LE L +FD L L L L N + +I PL L+N L + + P N+
Sbjct: 401 LENLPLGIFDHLGKLCELRLYDNPWRCDSDILPLRNWLLLNQPRLGTDTVPVCFSPANVR 460
Query: 492 G 492
G
Sbjct: 461 G 461
>gi|30425563 reticulon 4 receptor-like 2 [Homo sapiens]
Length = 420
Score = 100 bits (250), Expect = 4e-21
Identities = 90/321 (28%), Positives = 133/321 (41%), Gaps = 59/321 (18%)
Query: 29 CKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNA 88
C + C C ++C+ F++V L PP + +LFL NL+ L P F SN
Sbjct: 31 CPMLCTCYSSPPT--VSCQANNFSSVPLSLPPSTQ--RLFLQNNLIRTLRPGTFG--SNL 84
Query: 89 VTLHLGNNGLQEIRTGAF-------------------------SGLKTLKRLHLNNNKLE 123
+TL L +N L I G F GL+ L+ LHL +L
Sbjct: 85 LTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLS 144
Query: 124 ILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFV-L 182
L + F GL SL+YL N + ++ F+ L L L L+ N L L +VFR +
Sbjct: 145 SLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGS 204
Query: 183 LTHLDLRGNRLKVM---PFAGV--------------------LEHIGGIMEIQLEENPWN 219
L L L GNRL+ + F G+ L + + ++L NPW
Sbjct: 205 LDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNANPWA 264
Query: 220 CTCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDL--CPRKSAS--DSSQRG 275
C C PL AW V ++ C TP G+D+ L D CP + + S RG
Sbjct: 265 CDCRARPLWAWFQRARVSSSDVTCATPPERQGRDLRALREADFQACPPAAPTRPGSRARG 324
Query: 276 SHADTHVQRLSPTMNPALNPT 296
+ + H+ ++ P +P+
Sbjct: 325 NSSSNHLYGVAEAGAPPADPS 345
Score = 100 bits (248), Expect = 7e-21
Identities = 88/299 (29%), Positives = 127/299 (42%), Gaps = 57/299 (19%)
Query: 339 TCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPK-------------------- 378
+CP C C S V+CQ F+++ P T
Sbjct: 30 SCPMLCTCYSSPP----TVSCQANNFSSVPLSLPPSTQRLFLQNNLIRTLRPGTFGSNLL 85
Query: 379 KLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNR-IAVIQEGAFTNLTSLRRLYLNGNYLEV 437
L+L N L T+Y +L+ L LG+NR + ++ F L L+ L+L L
Sbjct: 86 TLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSS 145
Query: 438 LYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGG---- 493
L ++F GL SLQYLYL+ N + ++ F L NL LFL+ N LR L +++F G
Sbjct: 146 LPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSL 205
Query: 494 ---------------------TALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWD 532
+ LT L L NN + LP + + D LP+ + L NPW
Sbjct: 206 DRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALAD-LPSLEFLRLNANPWA 264
Query: 533 CTCDIMGLKDWTEHANSPVIINEVTCESPAKHAGEILKFLGREA---ICPDSPNLSDGT 588
C C L W + A V ++VTC +P + G L+ L REA CP + G+
Sbjct: 265 CDCRARPLWAWFQRAR--VSSSDVTCATPPERQGRDLRAL-READFQACPPAAPTRPGS 320
>gi|198041768 synleurin [Homo sapiens]
Length = 622
Score = 99.4 bits (246), Expect = 1e-20
Identities = 67/232 (28%), Positives = 112/232 (48%), Gaps = 30/232 (12%)
Query: 380 LYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLY 439
L L+ N + + ++ +L L+LG+N + + AF L SLRRL L+ N +E +
Sbjct: 185 LDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQ 244
Query: 440 PSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFG------- 492
P F GL +L+YL L+ + I+ + F + NL+ L L++N L +L + F
Sbjct: 245 PFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIY 304
Query: 493 -------------------GTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDC 533
G +L LNL N+ + L + VL L + I + NPW+C
Sbjct: 305 LKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHPR-VLKPLSSLIHLQANSNPWEC 363
Query: 534 TCDIMGLKDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLS 585
C ++GL+DW A+S + +N + C++P G L+++ S N+S
Sbjct: 364 NCKLLGLRDWL--ASSAITLN-IYCQNPPSMRGRALRYINITNCVTSSINVS 412
Score = 98.2 bits (243), Expect = 3e-20
Identities = 66/211 (31%), Positives = 107/211 (50%), Gaps = 26/211 (12%)
Query: 67 LFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILR 126
L L+ N + R+ + F + N L+LG+N L ++ + AF LK+L+RL L++N +E ++
Sbjct: 185 LDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQ 244
Query: 127 EDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVL-LTH 185
F GL +LEYL + I + FS +N LK LIL+ N L +L S+ F + L +
Sbjct: 245 PFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIY 304
Query: 186 LDLRGNR---------------LKVMPFA---------GVLEHIGGIMEIQLEENPWNCT 221
L L NR LK++ + VL+ + ++ +Q NPW C
Sbjct: 305 LKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLIHLQANSNPWECN 364
Query: 222 CDLLPLKAWLDTITVFVGEIVCETPFRLHGK 252
C LL L+ WL + + + I C+ P + G+
Sbjct: 365 CKLLGLRDWLASSAITL-NIYCQNPPSMRGR 394
Score = 87.8 bits (216), Expect = 4e-17
Identities = 63/180 (35%), Positives = 93/180 (51%), Gaps = 14/180 (7%)
Query: 338 LTCPSSC-VCTSQSSDNGLNVNCQERKFTNISDLQPK--PTSPKKLYLTGNYLQTVYKND 394
L C S C +CT G +NC+ ++I PK P S LYLTGN + + +++
Sbjct: 30 LGCSSVCQLCT------GRQINCRNLGLSSI----PKNFPESTVFLYLTGNNISYINESE 79
Query: 395 LLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYL 454
L SL L+L N+ I + AF L L L+LN N+++ L P +F GL +L+ LYL
Sbjct: 80 LTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYL 139
Query: 455 EYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIF-GGTALTRLNLRNNHFSHLPVKG 513
+YN + + F+ L+++Q L L N L L F G AL L+L NN+ + G
Sbjct: 140 QYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESG 199
Score = 74.3 bits (181), Expect = 4e-13
Identities = 48/138 (34%), Positives = 68/138 (49%), Gaps = 2/138 (1%)
Query: 64 IYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLE 123
+Y LFLN N + RL P F N L+L N + + G F+ L +++ L+L N+L
Sbjct: 110 LYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLT 169
Query: 124 ILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFV-L 182
+L TF+G+ +L L N I I F L L L L N L +PSN F +
Sbjct: 170 VLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKS 229
Query: 183 LTHLDLRGNRLK-VMPFA 199
L L L N ++ + PFA
Sbjct: 230 LRRLSLSHNPIEAIQPFA 247
Score = 68.6 bits (166), Expect = 2e-11
Identities = 53/174 (30%), Positives = 85/174 (48%), Gaps = 4/174 (2%)
Query: 44 INCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRT 103
INC N G +++ P+ ++ L+L GN ++ + +E + V L+L N+ + +
Sbjct: 44 INCRNLGLSSIPK-NFPESTVF-LYLTGNNISYINESELTGLHSLVALYLDNSNILYVYP 101
Query: 104 GAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVL 163
AF L+ L L LNNN ++ L F GL +L L YN +S + G F+ L ++ L
Sbjct: 102 KAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYL 161
Query: 164 ILNDNLLLSLPSNVF-RFVLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEEN 216
L N L L S F V L LDL N + + +G +H+ + + L N
Sbjct: 162 NLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESG-FQHLENLACLYLGSN 214
Score = 67.8 bits (164), Expect = 4e-11
Identities = 42/157 (26%), Positives = 79/157 (50%), Gaps = 2/157 (1%)
Query: 62 YRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNK 121
+ + L+L+ + + +YP FV + L L NN ++ + G F GL L+ L+L N+
Sbjct: 84 HSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQ 143
Query: 122 LEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFV 181
+ + F L S++YL N ++ + +G F + L++L L++N +L + + F+ +
Sbjct: 144 VSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHL 203
Query: 182 -LLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENP 217
L L L N L +P + E + + + L NP
Sbjct: 204 ENLACLYLGSNNLTKVP-SNAFEVLKSLRRLSLSHNP 239
Score = 35.4 bits (80), Expect = 0.22
Identities = 27/81 (33%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 378 KKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNL-TSLRRLYLNGNYLE 436
K L L+ N L+ + + +L L L NRI I F N+ SL+ L L+ N L
Sbjct: 279 KHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLT 338
Query: 437 VLYPSMFDGLQSLQYLYLEYN 457
L+P + L SL +L N
Sbjct: 339 ALHPRVLKPLSSLIHLQANSN 359
>gi|34577057 fibronectin leucine rich transmembrane protein 1 [Homo
sapiens]
Length = 674
Score = 96.3 bits (238), Expect = 1e-19
Identities = 76/228 (33%), Positives = 119/228 (52%), Gaps = 17/228 (7%)
Query: 352 DNGLN-VNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNR 410
DN ++ V+ +E F + L K L+L+ N+L ++ L ++ L+ L L +NR
Sbjct: 160 DNSVSTVSIEEDAFADSKQL-------KLLFLSRNHLSSIPSG--LPHT-LEELRLDDNR 209
Query: 411 IAVIQEGAFTNLTSLRRLYLNGNYL--EVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFD 468
I+ I AF L SLRRL L+GN L + + F LQ+L L L N + PL
Sbjct: 210 ISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAA-PPLNLP 268
Query: 469 ALINLQLLFLNNNLLRSLPDNIFGGTA-LTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQ 527
+ +LQ L+L +N + +P N L RL+L NN+ + LP +G+ D L Q+ L+
Sbjct: 269 SA-HLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNLTTLP-RGLFDDLGNLAQLLLR 326
Query: 528 ENPWDCTCDIMGLKDWTEHANSPVIINEVTCESPAKHAGEILKFLGRE 575
NPW C C++M L+DW + + V + + C+ P K G +K + E
Sbjct: 327 NNPWFCGCNLMWLRDWVKARAAVVNVRGLMCQGPEKVRGMAIKDITSE 374
Score = 78.6 bits (192), Expect = 2e-14
Identities = 60/207 (28%), Positives = 103/207 (49%), Gaps = 14/207 (6%)
Query: 91 LHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKL--EILREDTFLGLESLEYLQADYNYISA 148
L L +N + I AF GL +L+RL L+ N L + + +DTF L++L L N ++A
Sbjct: 203 LRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAA 262
Query: 149 IEAGAFSKLNKLKVLILNDNLLLSLPSNVF-RFVLLTHLDLRGNRLKVMPFAGVLEHIGG 207
S L+ L L DN + +P N + L LDL N L +P G+ + +G
Sbjct: 263 PPLNLPSA--HLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNLTTLP-RGLFDDLGN 319
Query: 208 IMEIQLEENPWNCTCDLLPLKAWLD--TITVFVGEIVCETPFRLHGKDVTQLTRQ-DLC- 263
+ ++ L NPW C C+L+ L+ W+ V V ++C+ P ++ G + +T + D C
Sbjct: 320 LAQLLLRNNPWFCGCNLMWLRDWVKARAAVVNVRGLMCQGPEKVRGMAIKDITSEMDECF 379
Query: 264 ---PRKSASDSSQRGSHADTHVQRLSP 287
P+ ++++ + + A H +P
Sbjct: 380 ETGPQGGVANAAAK-TTASNHASATTP 405
Score = 33.1 bits (74), Expect = 1.1
Identities = 19/64 (29%), Positives = 27/64 (42%)
Query: 57 LQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLH 116
L P + +L+L N ++ + N L L NN L + G F L L +L
Sbjct: 265 LNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQLL 324
Query: 117 LNNN 120
L NN
Sbjct: 325 LRNN 328
>gi|38202222 fibronectin leucine rich transmembrane protein 3
precursor [Homo sapiens]
Length = 649
Score = 95.9 bits (237), Expect = 1e-19
Identities = 75/242 (30%), Positives = 120/242 (49%), Gaps = 15/242 (6%)
Query: 380 LYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEV-- 437
L+L+ N+L T+ +++ L L +NRI+ I + LTSL+RL L+GN L
Sbjct: 159 LFLSRNHLSTIPWG---LPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHG 215
Query: 438 LYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTA-L 496
L +F L +L L L N + P+ NL+ L+L +N + +P N F L
Sbjct: 216 LGDKVFFNLVNLTELSLVRNSLTAA-PVNLPGT-NLRKLYLQDNHINRVPPNAFSYLRQL 273
Query: 497 TRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEV 556
RL++ NN+ S+LP +G+ D L Q+ L+ NPW C C + ++DW + V + +
Sbjct: 274 YRLDMSNNNLSNLP-QGIFDDLDNITQLILRNNPWYCGCKMKWVRDWLQSLPVKVNVRGL 332
Query: 557 TCESPAKHAGEILKFLGREAI-CPDSPNLSDGTVLSMNHNTDTPRSLSVSPSSYPELHTE 615
C++P K G +K L E C DS G V ++ T P ++ + +P T+
Sbjct: 333 MCQAPEKVRGMAIKDLNAELFDCKDS-----GIVSTIQITTAIPNTVYPAQGQWPAPVTK 387
Query: 616 VP 617
P
Sbjct: 388 QP 389
Score = 74.7 bits (182), Expect = 3e-13
Identities = 66/241 (27%), Positives = 110/241 (45%), Gaps = 22/241 (9%)
Query: 91 LHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEI--LREDTFLGLESLEYLQADYNYISA 148
L L +N + I + + GL +LKRL L+ N L L + F L +L L N ++A
Sbjct: 180 LRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTA 239
Query: 149 IEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVL-LTHLDLRGNRLKVMPFAGVLEHIGG 207
L+ L L DN + +P N F ++ L LD+ N L +P G+ + +
Sbjct: 240 APVNLPG--TNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLP-QGIFDDLDN 296
Query: 208 IMEIQLEENPWNCTCDLLPLKAWLDTITVFVG--EIVCETPFRLHGKDVTQLTRQDLCPR 265
I ++ L NPW C C + ++ WL ++ V V ++C+ P ++ G + L +
Sbjct: 297 ITQLILRNNPWYCGCKMKWVRDWLQSLPVKVNVRGLMCQAPEKVRGMAIKDLNAE----- 351
Query: 266 KSASDSSQRGSHADTHVQRLSP-TMNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSF 324
D G + + P T+ PA AP ++ P ++N P++T KD Q+
Sbjct: 352 --LFDCKDSGIVSTIQITTAIPNTVYPAQGQWPAP-VTKQPDIKN---PKLT--KDHQTT 403
Query: 325 G 325
G
Sbjct: 404 G 404
Score = 55.5 bits (132), Expect = 2e-07
Identities = 53/192 (27%), Positives = 80/192 (41%), Gaps = 14/192 (7%)
Query: 1 MLSGVW--FLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQ 58
M+S W FL + LQ C C C+ I C ++ T++
Sbjct: 1 MISAAWSIFLIGTKIGLFLQVAPLSVMAKSCPSVCRCDAGF----IYCNDRFLTSIPTGI 56
Query: 59 PPQYRIYQLFLNGNLLTRL-YPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHL 117
P L+L N + P++ N ++L +N L E T K +K LHL
Sbjct: 57 PEDATT--LYLQNNQINNAGIPSDLKNLLKVERIYLYHNSLDEFPTNL---PKYVKELHL 111
Query: 118 NNNKLEILREDTFLGLESLEYLQADYNYISA--IEAGAFSKLNKLKVLILNDNLLLSLPS 175
N + + D+ + LE L D N +SA IE GAF N L++L L+ N L ++P
Sbjct: 112 QENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPW 171
Query: 176 NVFRFVLLTHLD 187
+ R + LD
Sbjct: 172 GLPRTIEELRLD 183
Score = 37.0 bits (84), Expect = 0.077
Identities = 20/68 (29%), Positives = 31/68 (45%)
Query: 53 TVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTL 112
T + + P + +L+L N + R+ PN F L + NN L + G F L +
Sbjct: 238 TAAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNI 297
Query: 113 KRLHLNNN 120
+L L NN
Sbjct: 298 TQLILRNN 305
Score = 35.8 bits (81), Expect = 0.17
Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Query: 375 TSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGN- 433
T+ +KLYL N++ V N L L + NN ++ + +G F +L ++ +L L N
Sbjct: 247 TNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNNP 306
Query: 434 -YLEVLYPSMFDGLQSL 449
Y + D LQSL
Sbjct: 307 WYCGCKMKWVRDWLQSL 323
Score = 32.7 bits (73), Expect = 1.4
Identities = 18/54 (33%), Positives = 30/54 (55%)
Query: 86 SNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYL 139
+N L+L +N + + AFS L+ L RL ++NN L L + F L+++ L
Sbjct: 247 TNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQL 300
>gi|7019383 fibronectin leucine rich transmembrane protein 3
precursor [Homo sapiens]
Length = 649
Score = 95.9 bits (237), Expect = 1e-19
Identities = 75/242 (30%), Positives = 120/242 (49%), Gaps = 15/242 (6%)
Query: 380 LYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEV-- 437
L+L+ N+L T+ +++ L L +NRI+ I + LTSL+RL L+GN L
Sbjct: 159 LFLSRNHLSTIPWG---LPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHG 215
Query: 438 LYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTA-L 496
L +F L +L L L N + P+ NL+ L+L +N + +P N F L
Sbjct: 216 LGDKVFFNLVNLTELSLVRNSLTAA-PVNLPGT-NLRKLYLQDNHINRVPPNAFSYLRQL 273
Query: 497 TRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEV 556
RL++ NN+ S+LP +G+ D L Q+ L+ NPW C C + ++DW + V + +
Sbjct: 274 YRLDMSNNNLSNLP-QGIFDDLDNITQLILRNNPWYCGCKMKWVRDWLQSLPVKVNVRGL 332
Query: 557 TCESPAKHAGEILKFLGREAI-CPDSPNLSDGTVLSMNHNTDTPRSLSVSPSSYPELHTE 615
C++P K G +K L E C DS G V ++ T P ++ + +P T+
Sbjct: 333 MCQAPEKVRGMAIKDLNAELFDCKDS-----GIVSTIQITTAIPNTVYPAQGQWPAPVTK 387
Query: 616 VP 617
P
Sbjct: 388 QP 389
Score = 74.7 bits (182), Expect = 3e-13
Identities = 66/241 (27%), Positives = 110/241 (45%), Gaps = 22/241 (9%)
Query: 91 LHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEI--LREDTFLGLESLEYLQADYNYISA 148
L L +N + I + + GL +LKRL L+ N L L + F L +L L N ++A
Sbjct: 180 LRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTA 239
Query: 149 IEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVL-LTHLDLRGNRLKVMPFAGVLEHIGG 207
L+ L L DN + +P N F ++ L LD+ N L +P G+ + +
Sbjct: 240 APVNLPG--TNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLP-QGIFDDLDN 296
Query: 208 IMEIQLEENPWNCTCDLLPLKAWLDTITVFVG--EIVCETPFRLHGKDVTQLTRQDLCPR 265
I ++ L NPW C C + ++ WL ++ V V ++C+ P ++ G + L +
Sbjct: 297 ITQLILRNNPWYCGCKMKWVRDWLQSLPVKVNVRGLMCQAPEKVRGMAIKDLNAE----- 351
Query: 266 KSASDSSQRGSHADTHVQRLSP-TMNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSF 324
D G + + P T+ PA AP ++ P ++N P++T KD Q+
Sbjct: 352 --LFDCKDSGIVSTIQITTAIPNTVYPAQGQWPAP-VTKQPDIKN---PKLT--KDHQTT 403
Query: 325 G 325
G
Sbjct: 404 G 404
Score = 55.5 bits (132), Expect = 2e-07
Identities = 53/192 (27%), Positives = 80/192 (41%), Gaps = 14/192 (7%)
Query: 1 MLSGVW--FLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQ 58
M+S W FL + LQ C C C+ I C ++ T++
Sbjct: 1 MISAAWSIFLIGTKIGLFLQVAPLSVMAKSCPSVCRCDAGF----IYCNDRFLTSIPTGI 56
Query: 59 PPQYRIYQLFLNGNLLTRL-YPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHL 117
P L+L N + P++ N ++L +N L E T K +K LHL
Sbjct: 57 PEDATT--LYLQNNQINNAGIPSDLKNLLKVERIYLYHNSLDEFPTNL---PKYVKELHL 111
Query: 118 NNNKLEILREDTFLGLESLEYLQADYNYISA--IEAGAFSKLNKLKVLILNDNLLLSLPS 175
N + + D+ + LE L D N +SA IE GAF N L++L L+ N L ++P
Sbjct: 112 QENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPW 171
Query: 176 NVFRFVLLTHLD 187
+ R + LD
Sbjct: 172 GLPRTIEELRLD 183
Score = 37.0 bits (84), Expect = 0.077
Identities = 20/68 (29%), Positives = 31/68 (45%)
Query: 53 TVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTL 112
T + + P + +L+L N + R+ PN F L + NN L + G F L +
Sbjct: 238 TAAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNI 297
Query: 113 KRLHLNNN 120
+L L NN
Sbjct: 298 TQLILRNN 305
Score = 35.8 bits (81), Expect = 0.17
Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Query: 375 TSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGN- 433
T+ +KLYL N++ V N L L + NN ++ + +G F +L ++ +L L N
Sbjct: 247 TNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNNP 306
Query: 434 -YLEVLYPSMFDGLQSL 449
Y + D LQSL
Sbjct: 307 WYCGCKMKWVRDWLQSL 323
Score = 32.7 bits (73), Expect = 1.4
Identities = 18/54 (33%), Positives = 30/54 (55%)
Query: 86 SNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYL 139
+N L+L +N + + AFS L+ L RL ++NN L L + F L+++ L
Sbjct: 247 TNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQL 300
>gi|153251229 chondroadherin precursor [Homo sapiens]
Length = 359
Score = 95.5 bits (236), Expect = 2e-19
Identities = 66/218 (30%), Positives = 99/218 (45%), Gaps = 34/218 (15%)
Query: 380 LYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLY 439
LYL N + + + L +L +L L NN+I ++ GAF LR LYL+ N L L
Sbjct: 128 LYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQ 187
Query: 440 PSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIF-------- 491
P D +++L +++ N + L ++ L L++N L+S+PDN F
Sbjct: 188 PGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLE 247
Query: 492 ------------------GGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDC 533
G T L ++L NN + LP D L + L NPW C
Sbjct: 248 TLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPSNFPFDSLET---LALTNNPWKC 304
Query: 534 TCDIMGLKDWTE-HANSPVIINEVTCESPAKHAGEILK 570
TC + GL+ W E A+ P + TC SPAK G+ ++
Sbjct: 305 TCQLRGLRRWLEAKASRP----DATCASPAKFKGQHIR 338
Score = 88.6 bits (218), Expect = 2e-17
Identities = 66/241 (27%), Positives = 102/241 (42%), Gaps = 35/241 (14%)
Query: 67 LFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILR 126
L+L+ N +T L N L L NN ++E+R GAF G K L+ L+L+ N L L+
Sbjct: 128 LYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQ 187
Query: 127 EDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFR------- 179
+E+L D N +S+ + A SKL ++ L L+ N L S+P N F+
Sbjct: 188 PGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLE 247
Query: 180 -------------------FVLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNC 220
L H+ L NRL +P + + + L NPW C
Sbjct: 248 TLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPSNFPFD---SLETLALTNNPWKC 304
Query: 221 TCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADT 280
TC L L+ WL+ + C +P + G+ + +D +S ++R A
Sbjct: 305 TCQLRGLRRWLEA-KASRPDATCASPAKFKGQHI-----RDTDAFRSCKFPTKRSKKAGR 358
Query: 281 H 281
H
Sbjct: 359 H 359
Score = 77.8 bits (190), Expect = 4e-14
Identities = 63/196 (32%), Positives = 84/196 (42%), Gaps = 9/196 (4%)
Query: 335 PVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKND 394
P CP +C C S +V C + I + K K L L N + N
Sbjct: 18 PALAACPQNCHCHSDLQ----HVICDKVGLQKIPKVSEKT---KLLNLQRNNFPVLAANS 70
Query: 395 LLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYL 454
+L LHL + +I + GAF L L LYL+ N + VL FD L L YLYL
Sbjct: 71 FRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYL 130
Query: 455 EYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIF-GGTALTRLNLRNNHFSHLPVKG 513
++N + E+ L+NL +L LNNN +R L F G L L L N S L G
Sbjct: 131 DHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQ-PG 189
Query: 514 VLDQLPAFIQIDLQEN 529
LD + + + N
Sbjct: 190 ALDDVENLAKFHVDRN 205
Score = 72.8 bits (177), Expect = 1e-12
Identities = 61/217 (28%), Positives = 100/217 (46%), Gaps = 13/217 (5%)
Query: 1 MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPP 60
M+ + LS+ +AG+L A C C C ++ ++ C+ G + +
Sbjct: 1 MVRPMLLLSLGLLAGLLP------ALAACPQNCHCHS--DLQHVICDKVGLQKIPKVSE- 51
Query: 61 QYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNN 120
+ L L N L N F N V+LHL + ++E+ GAF GLK L L+L++N
Sbjct: 52 --KTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHN 109
Query: 121 KLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRF 180
+ +LR F L L YL D+N ++ + G S L L +L LN+N + L + F+
Sbjct: 110 DIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQG 169
Query: 181 VL-LTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEEN 216
L L L N L + G L+ + + + ++ N
Sbjct: 170 AKDLRWLYLSENALSSLQ-PGALDDVENLAKFHVDRN 205
>gi|10190722 leucine-rich repeats and transmembrane domains 1 [Homo
sapiens]
Length = 345
Score = 93.2 bits (230), Expect = 9e-19
Identities = 78/287 (27%), Positives = 124/287 (43%), Gaps = 36/287 (12%)
Query: 29 CKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNA 88
C +C C+ N ++C +G + PPQ R
Sbjct: 21 CPDKCYCQSSTNF--VDCSQQGLAEIPSHLPPQTR------------------------- 53
Query: 89 VTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISA 148
TLHL +N + + AF + L L+L+NN L L F GL+ L+ L N + +
Sbjct: 54 -TLHLQDNQIHHLPAFAFRSVPWLMTLNLSNNSLSNLAPGAFHGLQHLQVLNLTQNSLLS 112
Query: 149 IEAGAFSKLNKLKVLILNDNLLLSLPSNVFR-FVLLTHLDLRGNRLKVMPFAGVLEHIGG 207
+E+ F L +L+ L L+ N + LP+++ + LT L ++ N+L+ + A +LE +
Sbjct: 113 LESRLFHSLPQLRELDLSSNNISHLPTSLGETWENLTILAVQQNQLQQLDRA-LLESMPS 171
Query: 208 IMEIQLEENPWNCTCDLLPLKAWLDTITVFVG---EIVCETPFRLHGKDVTQLTRQ--DL 262
+ + L++N W C C LL LK WL+ G I+CE+P GKD+ ++ +
Sbjct: 172 VRLLLLKDNLWKCNCHLLGLKLWLEKFVYKGGLTDGIICESPDTWKGKDLLRIPHELYQP 231
Query: 263 CPRKSASD-SSQRGSHADTHVQRLSPTMNPALNPTRAPKASRPPKMR 308
CP + SSQ H L P N + PK R
Sbjct: 232 CPLPAPDPVSSQAQWPGSAHGVVLRPPENHNAGERELLECELKPKPR 278
Score = 83.2 bits (204), Expect = 9e-16
Identities = 87/325 (26%), Positives = 134/325 (41%), Gaps = 52/325 (16%)
Query: 336 VPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDL 395
V +CP C C QSS N V+C ++ I P T
Sbjct: 17 VVCSCPDKCYC--QSSTNF--VDCSQQGLAEIPSHLPPQTRT------------------ 54
Query: 396 LEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLE 455
LHL +N+I + AF ++ L L L+ N L L P F GLQ LQ L L
Sbjct: 55 --------LHLQDNQIHHLPAFAFRSVPWLMTLNLSNNSLSNLAPGAFHGLQHLQVLNLT 106
Query: 456 YNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGT--ALTRLNLRNNHFSHLPVKG 513
N + ++ F +L L+ L L++N + LP ++ G T LT L ++ N L +
Sbjct: 107 QNSLLSLESRLFHSLPQLRELDLSSNNISHLPTSL-GETWENLTILAVQQNQLQQLD-RA 164
Query: 514 VLDQLPAFIQIDLQENPWDCTCDIMGLKDWTE-HANSPVIINEVTCESPAKHAGEILKFL 572
+L+ +P+ + L++N W C C ++GLK W E + + + CESP G+ L +
Sbjct: 165 LLESMPSVRLLLLKDNLWKCNCHLLGLKLWLEKFVYKGGLTDGIICESPDTWKGKDLLRI 224
Query: 573 GREAI--CP-----------DSPNLSDGTVL--SMNHNTDTPRSL--SVSPSSYPELHTE 615
E CP P + G VL NHN L + P P
Sbjct: 225 PHELYQPCPLPAPDPVSSQAQWPGSAHGVVLRPPENHNAGERELLECELKPKPRPANLRH 284
Query: 616 VPLSVLILGLLVVFILSVCFGAGLF 640
+V+I G++ + + A ++
Sbjct: 285 AIATVIITGVVCGIVCLMMLAAAIY 309
>gi|84781739 leucine-rich repeats and transmembrane domains 2 [Homo
sapiens]
Length = 370
Score = 91.7 bits (226), Expect = 3e-18
Identities = 76/291 (26%), Positives = 110/291 (37%), Gaps = 36/291 (12%)
Query: 29 CKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNA 88
C C C+ + L ++C G TTV P R L L N L+ L F N S+
Sbjct: 39 CPFSCKCDSRS--LEVDCSGLGLTTVPPDVPAATRT--LLLLNNKLSALPSWAFANLSSL 94
Query: 89 VTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISA 148
L L NN L + F L L L L NN + L D L +L N ++
Sbjct: 95 QRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSIRTLDRDLLRHSPLLRHLDLSINGLAQ 154
Query: 149 IEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHIGGI 208
+ G F L L+ L L N L +L F E + +
Sbjct: 155 LPPGLFDGLLALRSLSLRSNRLQNLDRLTF------------------------EPLANL 190
Query: 209 MEIQLEENPWNCTCDLLPLKAWLDTITVFVG---EIVCETPFRLHGKDVTQLTRQ--DLC 263
+Q+ +NPW C C+L K W++ + G ++ C P L GKD+ + + + C
Sbjct: 191 QLLQVGDNPWECDCNLREFKHWMEWFSYRGGRLDQLACTLPKELRGKDMRMVPMEMFNYC 250
Query: 264 PRKSASDSSQRGSHADTHVQRLSP---TMNPALNPTRAPKASRPPKMRNRP 311
+ +SS + SP P P P + P K R+RP
Sbjct: 251 SQLEDENSSAGLDIPGPPCTKASPEPAKPKPGAEPEPEPSTACPQKQRHRP 301
Score = 66.2 bits (160), Expect = 1e-10
Identities = 51/165 (30%), Positives = 76/165 (46%), Gaps = 26/165 (15%)
Query: 339 TCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPT----------------------S 376
TCP SC C S+S L V+C T + P T S
Sbjct: 38 TCPFSCKCDSRS----LEVDCSGLGLTTVPPDVPAATRTLLLLNNKLSALPSWAFANLSS 93
Query: 377 PKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLE 436
++L L+ N+L + ++ + ++L L L NN I + + LR L L+ N L
Sbjct: 94 LQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSIRTLDRDLLRHSPLLRHLDLSINGLA 153
Query: 437 VLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNN 481
L P +FDGL +L+ L L N ++ + LTF+ L NLQLL + +N
Sbjct: 154 QLPPGLFDGLLALRSLSLRSNRLQNLDRLTFEPLANLQLLQVGDN 198
>gi|30425553 reticulon 4 receptor-like 1 [Homo sapiens]
Length = 441
Score = 91.7 bits (226), Expect = 3e-18
Identities = 86/295 (29%), Positives = 118/295 (40%), Gaps = 53/295 (17%)
Query: 327 IMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISD----------------- 369
+++ + P+ CP CVC + V+CQ F I +
Sbjct: 12 LLLVAAELPLGGGCPRDCVCYPAP----MTVSCQAHNFAAIPEGIPVDSERVFLQNNRIG 67
Query: 370 -LQPKPTSPKK--LYLTGNYLQTVYKNDLLEYSSLDLLHLGNNR-IAVIQEGAFTNLTSL 425
LQP SP L++ N + ++ + + L+ L LG+NR + + F L L
Sbjct: 68 LLQPGHFSPAMVTLWIYSNNITYIHPSTFEGFVHLEELDLGDNRQLRTLAPETFQGLVKL 127
Query: 426 RRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRS 485
LYL L L +F GL SLQYLYL+ N I+ ++ F L+NL LFL+ N L S
Sbjct: 128 HALYLYKCGLSALPAGVFGGLHSLQYLYLQDNHIEYLQDDIFVDLVNLSHLFLHGNKLWS 187
Query: 486 LPDNIFGGTA-------------------------LTRLNLRNNHFSHLPVKGVLDQLPA 520
L F G LT L L NN S L + L L A
Sbjct: 188 LGPGTFRGLVNLDRLLLHENQLQWVHHKAFHDLRRLTTLFLFNNSLSELQGE-CLAPLGA 246
Query: 521 FIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVTCESPAKHAGEILKFLGRE 575
+ L NPWDC C L +W + + V C SP G+ LK L E
Sbjct: 247 LEFLRLNGNPWDCGCRARSLWEWLQRFRGS--SSAVPCVSPGLRHGQDLKLLRAE 299
Score = 88.2 bits (217), Expect = 3e-17
Identities = 79/303 (26%), Positives = 129/303 (42%), Gaps = 38/303 (12%)
Query: 54 VSLLQPPQYR--IYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNN--------------- 96
+ LLQP + + L++ N +T ++P+ F + + L LG+N
Sbjct: 66 IGLLQPGHFSPAMVTLWIYSNNITYIHPSTFEGFVHLEELDLGDNRQLRTLAPETFQGLV 125
Query: 97 ----------GLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYI 146
GL + G F GL +L+ L+L +N +E L++D F+ L +L +L N +
Sbjct: 126 KLHALYLYKCGLSALPAGVFGGLHSLQYLYLQDNHIEYLQDDIFVDLVNLSHLFLHGNKL 185
Query: 147 SAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFV-LLTHLDLRGNRLKVMPFAGVLEHI 205
++ G F L L L+L++N L + F + LT L L N L + L +
Sbjct: 186 WSLGPGTFRGLVNLDRLLLHENQLQWVHHKAFHDLRRLTTLFLFNNSLSELQ-GECLAPL 244
Query: 206 GGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDLCPR 265
G + ++L NPW+C C L WL + C +P HG+D+ L +D
Sbjct: 245 GALEFLRLNGNPWDCGCRARSLWEWLQRFRGSSSAVPCVSPGLRHGQDLKLLRAEDFRNC 304
Query: 266 KSASDSSQRGSHADTHVQRLSPTMNPALN-PTRA--------PKASRPPKMRNRPTPRVT 316
+ Q SH T R + + + + PTR+ P +P K P R
Sbjct: 305 TGPASPHQIKSHTLTTTDRAARKEHHSPHGPTRSKGHPHGPRPGHRKPGKNCTNPRNRNQ 364
Query: 317 VSK 319
+SK
Sbjct: 365 ISK 367
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,201,994
Number of Sequences: 37866
Number of extensions: 1682503
Number of successful extensions: 8136
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 225
Number of HSP's successfully gapped in prelim test: 77
Number of HSP's that attempted gapping in prelim test: 4747
Number of HSP's gapped (non-prelim): 1602
length of query: 845
length of database: 18,247,518
effective HSP length: 111
effective length of query: 734
effective length of database: 14,044,392
effective search space: 10308583728
effective search space used: 10308583728
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.