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Search of human proteins with 219689110
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|219689110 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 2 [Homo sapiens]
(415 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|219689110 serine (or cysteine) proteinase inhibitor, clade B ... 831 0.0
gi|4505595 serine (or cysteine) proteinase inhibitor, clade B (o... 831 0.0
gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (... 361 e-100
gi|4826902 serine (or cysteine) proteinase inhibitor, clade B (o... 355 5e-98
gi|41152086 serine (or cysteine) proteinase inhibitor, clade B (... 343 2e-94
gi|38504669 serine (or cysteine) proteinase inhibitor, clade B (... 337 9e-93
gi|38504673 serine (or cysteine) proteinase inhibitor, clade B (... 337 9e-93
gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s... 331 8e-91
gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (... 305 5e-83
gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (o... 303 1e-82
gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Hom... 291 6e-79
gi|17998551 serine (or cysteine) proteinase inhibitor, clade B (... 288 6e-78
gi|8393956 serine (or cysteine) proteinase inhibitor, clade B (o... 284 9e-77
gi|92859634 serine (or cysteine) proteinase inhibitor, clade B (... 252 5e-67
gi|4505149 serine (or cysteine) proteinase inhibitor, clade B (o... 252 5e-67
gi|167860126 serine (or cysteine) proteinase inhibitor, clade B ... 240 2e-63
gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo s... 212 6e-55
gi|73623033 serine (or cysteine) proteinase inhibitor, clade B (... 197 1e-50
gi|170295807 neuroserpin precursor [Homo sapiens] 195 6e-50
gi|4826904 neuroserpin precursor [Homo sapiens] 195 6e-50
gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member... 189 4e-48
gi|110225347 serine (or cysteine) proteinase inhibitor, clade A ... 186 3e-47
gi|50659080 serpin peptidase inhibitor, clade A, member 3 precur... 183 3e-46
gi|73858566 heparin cofactor II precursor [Homo sapiens] 180 2e-45
gi|194018472 serine (or cysteine) proteinase inhibitor, clade A ... 179 5e-45
gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom... 174 1e-43
gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom... 174 1e-43
gi|189163538 serine proteinase inhibitor, clade A, member 1 [Hom... 174 1e-43
gi|189163536 serine proteinase inhibitor, clade A, member 1 [Hom... 174 1e-43
gi|189163534 serine proteinase inhibitor, clade A, member 1 [Hom... 174 1e-43
>gi|219689110 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 2 [Homo sapiens]
Length = 415
Score = 831 bits (2147), Expect = 0.0
Identities = 415/415 (100%), Positives = 415/415 (100%)
Query: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF
Sbjct: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
Query: 61 NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN
Sbjct: 61 NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK
Sbjct: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK
Sbjct: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
Query: 241 LNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKM 300
LNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKM
Sbjct: 241 LNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKM 300
Query: 301 AEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMV 360
AEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMV
Sbjct: 301 AEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMV 360
Query: 361 DVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
DVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP
Sbjct: 361 DVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
>gi|4505595 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 2 [Homo sapiens]
Length = 415
Score = 831 bits (2147), Expect = 0.0
Identities = 415/415 (100%), Positives = 415/415 (100%)
Query: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF
Sbjct: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
Query: 61 NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN
Sbjct: 61 NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK
Sbjct: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK
Sbjct: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
Query: 241 LNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKM 300
LNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKM
Sbjct: 241 LNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKM 300
Query: 301 AEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMV 360
AEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMV
Sbjct: 301 AEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMV 360
Query: 361 DVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
DVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP
Sbjct: 361 DVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
>gi|13489087 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 1 [Homo sapiens]
Length = 379
Score = 361 bits (927), Expect = e-100
Identities = 190/416 (45%), Positives = 263/416 (63%), Gaps = 38/416 (9%)
Query: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
ME L ANT FAL+LF L++ +P N+F+SP+SISS MAMV++G+RG+T Q++K F
Sbjct: 1 MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60
Query: 61 NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
N V +++HS F+SL++ IN +
Sbjct: 61 NTV-------------------------------------EEVHSRFQSLNADINKRGAS 83
Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
Y+L+ N+L+GEK+ +F E++ QK Y ++ +VDF +E+ARK IN WVK QT+GK
Sbjct: 84 YILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDFQHASEDARKTINQWVKGQTEGK 143
Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
IP LL G VD T++VLVNA+YFKG WK F K+ PFR+N R V+MMY ++K
Sbjct: 144 IPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKK 203
Query: 241 LNIGYIEDLKAQILELPYAG-DVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
GYIEDLK ++LELPY G ++SM +LLPD+I D STGL+ +E ++T +KL++WT +
Sbjct: 204 FAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTKPEN 263
Query: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
+ EV V +P+FKLEE Y L S L +G++D FN +A+ SGMS D+F+S++ H++
Sbjct: 264 LDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSSKADLSGMSGARDIFISKIVHKSF 323
Query: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
V+VNEEGTEAAA T G+ T F ADHPFLF I H + ILF GRFSSP
Sbjct: 324 VEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLFFIRHNSSGSILFLGRFSSP 379
>gi|4826902 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 10 [Homo sapiens]
Length = 397
Score = 355 bits (910), Expect = 5e-98
Identities = 190/416 (45%), Positives = 278/416 (66%), Gaps = 20/416 (4%)
Query: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
M+ L + FAL L K LA+++ +N+F S WSIS+++ +VY+G++G+T QMA+VLQF
Sbjct: 1 MDSLATSINQFALELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQF 60
Query: 61 NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
N + PE+ ++ +K + +++IHS F++L S I +
Sbjct: 61 NR---DQGVKCDPES-------EKKRKMEF-----NLSNSEEIHSDFQTLISEILKPNDD 105
Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
YLL++ N ++GEK+ +F +Y+ + Y+ +EPQ V+F+E +++ RK INSWV+ QT+GK
Sbjct: 106 YLLKTANAIYGEKTYAFHNKYLEDMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGK 165
Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
I NLLP+ SVD TRM+LVNA+YFKG W+ F + PFR+N PVQMM++++K
Sbjct: 166 IQNLLPDDSVDSTTRMILVNALYFKGIWEHQFLVQNTTEKPFRINETTSKPVQMMFMKKK 225
Query: 241 LNIGYIEDLKAQILELPYAG-DVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
L+I +IE KA L+L Y D+S+ +LLP++I GLE LE ITY+KLN+WTS D
Sbjct: 226 LHIFHIEKPKAVGLQLYYKSRDLSLLILLPEDI----NGLEQLEKAITYEKLNEWTSADM 281
Query: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
M EV++++P+FKLE+ Y+L+S L SMGM DAF++ +A+FSGMS +LFLS VFH+A
Sbjct: 282 MELYEVQLHLPKFKLEDSYDLKSTLSSMGMSDAFSQSKADFSGMSSARNLFLSNVFHKAF 341
Query: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
V++NE+GTEAAAG+G + R +F A+HPFLF I H TN ILF+GR SP
Sbjct: 342 VEINEQGTEAAAGSGSEIDIRIRVPSIEFNANHPFLFFIRHNKTNTILFYGRLCSP 397
>gi|41152086 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 6 [Homo sapiens]
Length = 376
Score = 343 bits (880), Expect = 2e-94
Identities = 189/416 (45%), Positives = 256/416 (61%), Gaps = 41/416 (9%)
Query: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
M+ L AN FALNL K L K + ++N+F SP S+S +AMVYMG++G+T QMA++L F
Sbjct: 1 MDVLAEANGTFALNLLKTLGKDN-SKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF 59
Query: 61 NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
N+ G IH F+SL + +N +
Sbjct: 60 NKSGGGG----------------------------------DIHQGFQSLLTEVNKTGTQ 85
Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
YLL N+LFGEKS F + CQK+Y +E + +DF+ E++RK IN+WV +T+GK
Sbjct: 86 YLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEKSRKHINTWVAEKTEGK 145
Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
I LL GSVD TR+VLVNAVYF+G W F+K+ F+V+ + PVQMM+ +
Sbjct: 146 IAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFKQST 205
Query: 241 LNIGYIEDLKAQILELPYAG-DVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
YI ++ QIL LPY G +++M ++LPDE D+ T +E E+TY+K +WT D
Sbjct: 206 FKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTDLRT----VEKELTYEKFVEWTRLDM 261
Query: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
M E+EVEV +P+FKLEE Y++ S+LR++GM DAF G+A+FSGMS+ DL LS+V H++
Sbjct: 262 MDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGMSQ-TDLSLSKVVHKSF 320
Query: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
V+VNEEGTEAAA T +M R P+F ADHPFLF I H TN ILF GRFSSP
Sbjct: 321 VEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFIQHSKTNGILFCGRFSSP 376
>gi|38504669 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform a [Homo sapiens]
Length = 374
Score = 337 bits (865), Expect = 9e-93
Identities = 180/416 (43%), Positives = 254/416 (61%), Gaps = 43/416 (10%)
Query: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
M+DLC AN FA++LFK L + ++N+F SP SISS +AMV+MG++GST QM++ L
Sbjct: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60
Query: 61 NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
+ G IH F+SL S +N +
Sbjct: 61 YKDG-------------------------------------DIHRGFQSLLSEVNRTGTQ 83
Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
YLL + N+LFGEK+ F ++ CQK+Y +E + + F E EE RK IN WV +T+GK
Sbjct: 84 YLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGK 143
Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
I +L G+VD T++VLVNA+YFKGKW F++K F+ N ++T VQMM+ K
Sbjct: 144 ISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTNEEKKT-VQMMFKEAK 202
Query: 241 LNIGYIEDLKAQILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
+GY +++ Q+LELPY + +SM +LLPD+ +T L ++E +TY+K WT+ +K
Sbjct: 203 FKMGYADEVHTQVLELPYVEEELSMVILLPDD----NTDLAVVEKALTYEKFKAWTNSEK 258
Query: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
+ + +V+V++P+ KLEE Y+L LR +GM DAF++ +A+FSGMS ++ LS+V H+
Sbjct: 259 LTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCF 318
Query: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
V+VNEEGTEAAA T V R P+F ADHPFLF I H TNCILF GRFSSP
Sbjct: 319 VEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374
>gi|38504673 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform a [Homo sapiens]
Length = 374
Score = 337 bits (865), Expect = 9e-93
Identities = 180/416 (43%), Positives = 254/416 (61%), Gaps = 43/416 (10%)
Query: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
M+DLC AN FA++LFK L + ++N+F SP SISS +AMV+MG++GST QM++ L
Sbjct: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60
Query: 61 NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
+ G IH F+SL S +N +
Sbjct: 61 YKDG-------------------------------------DIHRGFQSLLSEVNRTGTQ 83
Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
YLL + N+LFGEK+ F ++ CQK+Y +E + + F E EE RK IN WV +T+GK
Sbjct: 84 YLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGK 143
Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
I +L G+VD T++VLVNA+YFKGKW F++K F+ N ++T VQMM+ K
Sbjct: 144 ISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTNEEKKT-VQMMFKEAK 202
Query: 241 LNIGYIEDLKAQILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
+GY +++ Q+LELPY + +SM +LLPD+ +T L ++E +TY+K WT+ +K
Sbjct: 203 FKMGYADEVHTQVLELPYVEEELSMVILLPDD----NTDLAVVEKALTYEKFKAWTNSEK 258
Query: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
+ + +V+V++P+ KLEE Y+L LR +GM DAF++ +A+FSGMS ++ LS+V H+
Sbjct: 259 LTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCF 318
Query: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
V+VNEEGTEAAA T V R P+F ADHPFLF I H TNCILF GRFSSP
Sbjct: 319 VEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374
>gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo
sapiens]
Length = 376
Score = 331 bits (848), Expect = 8e-91
Identities = 175/417 (41%), Positives = 253/417 (60%), Gaps = 43/417 (10%)
Query: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
ME L A+ FA+ L K L + +P+ N+F SP SISS +AMV +G++G+T QMA+ L
Sbjct: 1 METLSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSL 60
Query: 61 NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
N + IH +F+SL + +N +
Sbjct: 61 N-------------------------------------TEEDIHRAFQSLLTEVNKAGTQ 83
Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
YLL + N+LFGEK+ F + C ++Y +E + + F+ AEE+RK IN+WV +T+GK
Sbjct: 84 YLLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELSFIRAAEESRKHINTWVSKKTEGK 143
Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
I LLP S+D +TR+VLVNA+YFKGKW PF++ PF++N ++ PVQMMY
Sbjct: 144 IEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYTREMPFKINQEEQRPVQMMYQEAT 203
Query: 241 LNIGYIEDLKAQILELPYA-GDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
+ ++ +++AQ+LELPYA ++S+ +LLPD+ ++ST +E +T++KL WT D
Sbjct: 204 FKLAHVGEVRAQLLELPYARKELSLLVLLPDDGVELST----VEKSLTFEKLTAWTKPDC 259
Query: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
M EVEV +P+FKL+E Y++ S+LR +G+ DAF +G+A+ S MS DL LS+ H++
Sbjct: 260 MKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADLSAMSAERDLCLSKFVHKSF 319
Query: 360 VDVNEEGTEAAAGTG-GVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
V+VNEEGTEAAA + V+ GP+F ADHPFLF I H N ILF GRFSSP
Sbjct: 320 VEVNEEGTEAAAASSCFVVAECCMESGPRFCADHPFLFFIRHNRANSILFCGRFSSP 376
>gi|28076869 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 4 [Homo sapiens]
Length = 390
Score = 305 bits (781), Expect = 5e-83
Identities = 172/417 (41%), Positives = 246/417 (58%), Gaps = 29/417 (6%)
Query: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
M L ANT F +LF+ K S N+F SP SI+S + MV +G++ +T Q++KVL F
Sbjct: 1 MNSLSEANTKFMFDLFQQFRK-SKENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHF 59
Query: 61 NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
++V N A + +H F+ L + N ST
Sbjct: 60 DQVTENTTEKA---------------------ATYHVDRSGNVHHQFQKLLTEFNKSTDA 98
Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
Y L+ NKLFGEK+ F +EY+ +K+Y + ++ DF EE+RKKINSWV++QT K
Sbjct: 99 YELKIANKLFGEKTYQFLQEYLDAIKKFYQTSVESTDFANAPEESRKKINSWVESQTNEK 158
Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
I NL P+G++ DT +VLVNA+YFKG+W+ F+K+ F N VQMM
Sbjct: 159 IKNLFPDGTIGNDTTLVLVNAIYFKGQWENKFKKENTKEEKFWPNKNTYKSVQMMRQYNS 218
Query: 241 LNIGYIEDLKAQILELPYAG-DVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
N +ED++A++LE+PY G D+SM +LLP+EI GL+ LE ++T +KL +WTS
Sbjct: 219 FNFALLEDVQAKVLEIPYKGKDLSMIVLLPNEI----DGLQKLEEKLTAEKLMEWTSLQN 274
Query: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
M E V++++P+FK+EE Y+L+ LR+MGM + FN G A+ SGM+ + L +S+V H+A
Sbjct: 275 MRETCVDLHLPRFKMEESYDLKDTLRTMGMVNIFN-GDADLSGMTWSHGLSVSKVLHKAF 333
Query: 360 VDVNEEGTEAAAGTGGVMTGRTGHG-GPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
V+V EEG EAAA T V+ + +F +HPFLF I TN ILF+GRFSSP
Sbjct: 334 VEVTEEGVEAAAATAVVVVELSSPSTNEEFCCNHPFLFFIRQNKTNSILFYGRFSSP 390
>gi|5902072 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 3 [Homo sapiens]
Length = 390
Score = 303 bits (777), Expect = 1e-82
Identities = 174/417 (41%), Positives = 244/417 (58%), Gaps = 29/417 (6%)
Query: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
M L ANT F +LF+ K S N+F SP SI+S + MV +G++ +T Q+ KVL F
Sbjct: 1 MNSLSEANTKFMFDLFQQFRK-SKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHF 59
Query: 61 NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
++V N A + +H F+ L + N ST
Sbjct: 60 DQVTENTTGKA---------------------ATYHVDRSGNVHHQFQKLLTEFNKSTDA 98
Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
Y L+ NKLFGEK+ F +EY+ +K+Y + ++VDF EE+RKKINSWV++QT K
Sbjct: 99 YELKIANKLFGEKTYLFLQEYLDAIKKFYQTSVESVDFANAPEESRKKINSWVESQTNEK 158
Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
I NL+PEG++ +T +VLVNA+YFKG+W+ F K+ F N +QMM
Sbjct: 159 IKNLIPEGNIGSNTTLVLVNAIYFKGQWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTS 218
Query: 241 LNIGYIEDLKAQILELPYAG-DVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
+ +ED++A++LE+PY G D+SM +LLP+EI GL+ LE ++T +KL +WTS
Sbjct: 219 FHFASLEDVQAKVLEIPYKGKDLSMIVLLPNEI----DGLQKLEEKLTAEKLMEWTSLQN 274
Query: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
M E V++++P+FK+EE Y+L+ LR+MGM D FN G A+ SGM+ L LS V H+A
Sbjct: 275 MRETRVDLHLPRFKVEESYDLKDTLRTMGMVDIFN-GDADLSGMTGSRGLVLSGVLHKAF 333
Query: 360 VDVNEEGTEAAAGTGGVMTGRTGHG-GPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
V+V EEG EAAA T V G + +F +HPFLF I TN ILF+GRFSSP
Sbjct: 334 VEVTEEGAEAAAATAVVGFGSSPTSTNEEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390
>gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Homo
sapiens]
Length = 392
Score = 291 bits (746), Expect = 6e-79
Identities = 161/416 (38%), Positives = 247/416 (59%), Gaps = 25/416 (6%)
Query: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
M L AN F L++FK L + N+F S S+ ++MV +G+RG TE+Q+ KVL F
Sbjct: 1 MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHF 60
Query: 61 NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
+ + V + P + D+ +QA +IHS F S IN N
Sbjct: 61 S----HTVDSLKP---------------GFKDSPKCSQAG-RIHSEFGVEFSQINQPDSN 100
Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
L N+L+G K+ +F ++Y+ +K+Y + Q VDF + EE RK IN+WV+ +T GK
Sbjct: 101 CTLSIANRLYGTKTMAFHQQYLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGK 160
Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
+ NL + ++D + MVLVNA+YFKG+W+ F+ + PF+++ + V+MMY
Sbjct: 161 VANLFGKSTIDPSSVMVLVNAIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGT 220
Query: 241 LNIGYIEDLKAQILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
+ ++++ + Q+LELPY + +SM +LLP IA+ L+ +E ++ ++WTS
Sbjct: 221 FKLAFVKEPQMQVLELPYVNNKLSMIILLPVGIAN----LKQIEKQLNSGTFHEWTSSSN 276
Query: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
M E EVEV++P+FKLE YEL S+L+S+G+ D FN+ +A+ SGMS L+LS+ H++
Sbjct: 277 MMEREVEVHLPRFKLETKYELNSLLKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSY 336
Query: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
+DV+EEGTEAAA TG + ++ QF A+HPFLF I H TN ILF G+ +SP
Sbjct: 337 LDVSEEGTEAAAATGDSIAVKSLPMRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392
>gi|17998551 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 12 [Homo sapiens]
Length = 405
Score = 288 bits (737), Expect = 6e-78
Identities = 159/416 (38%), Positives = 251/416 (60%), Gaps = 12/416 (2%)
Query: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
M+ L ANT F +LF+ + K +N+F SP S+S+ + MV +G+R + Q+ +VL F
Sbjct: 1 MDSLVTANTKFCFDLFQEIGKDDRHKNIFFSPLSLSAALGMVRLGARSDSAHQIDEVLHF 60
Query: 61 NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
NE N P C + + GS + + + F L S ++ +
Sbjct: 61 NEFSQNESKEPDP-----CLKSNKQKAGSLNNE------SGLVSCYFGQLLSKLDRIKTD 109
Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
Y L N+L+GE+ +EY+ ++Y + ++VDF + E++R++IN WV+ Q++GK
Sbjct: 110 YTLSIANRLYGEQEFPICQEYLDGVIQFYHTTIESVDFQKNPEKSRQEINFWVECQSQGK 169
Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
I L + +++ +T +VLVNAVYFK KW+T F+ + PF +N+ + V+MM +
Sbjct: 170 IKELFSKDAINAETVLVLVNAVYFKAKWETYFDHENTVDAPFCLNANENKSVKMMTQKGL 229
Query: 241 LNIGYIEDLKAQILELPYA-GDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
IG+IE++KAQILE+ Y G +SMF+LLP D GLE LE +ITY+K+ W+S +
Sbjct: 230 YRIGFIEEVKAQILEMRYTKGKLSMFVLLPSHSKDNLKGLEELERKITYEKMVAWSSSEN 289
Query: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
M+E+ V + P+F LE+ Y+L SIL+ MG+ D F++ RA+ +G+S +L+LS++ H+
Sbjct: 290 MSEESVVLSFPRFTLEDSYDLNSILQDMGITDIFDETRADLTGISPSPNLYLSKIIHKTF 349
Query: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
V+V+E GT+AAA TG V++ R+ +F A+HPFLF I H T ILF+GR SP
Sbjct: 350 VEVDENGTQAAAATGAVVSERSLRSWVEFNANHPFLFFIRHNKTQTILFYGRVCSP 405
>gi|8393956 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 13 [Homo sapiens]
Length = 391
Score = 284 bits (727), Expect = 9e-77
Identities = 161/416 (38%), Positives = 246/416 (59%), Gaps = 26/416 (6%)
Query: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
M+ L +T +LFK L K + N+F SP I + + MV +G+RG+T Q+ +V
Sbjct: 1 MDSLGAVSTRLGFDLFKELKKTNDG-NIFFSPVGILTAIGMVLLGTRGATASQLEEVFH- 58
Query: 61 NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
E T ++ +K + I +A +H F+ + I+ T +
Sbjct: 59 ------------SEKETKSSRIKAEEK----EVIENTEA---VHQQFQKFLTEISKLTND 99
Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
Y L N+LFGEK+ F ++Y+ +KYY + + VDF+ A+E+RKKINSWV+++T K
Sbjct: 100 YELNITNRLFGEKTYLFLQKYLDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEK 159
Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
I +L P+GS+ T++VLVN VYFKG+W F+K+ F +N + VQMM
Sbjct: 160 IKDLFPDGSISSSTKLVLVNMVYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHS 219
Query: 241 LNIGYIEDLKAQILELPYA-GDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
+ ++EDL+A+IL +PY D+SMF+LLP++I GLE + +I+ +KL +WTS
Sbjct: 220 FSFTFLEDLQAKILGIPYKNNDLSMFVLLPNDI----DGLEKIIDKISPEKLVEWTSPGH 275
Query: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
M E +V +++P+F++E+ Y+L ++L +MGM DAF++ +A++SGMS + L+ + H +
Sbjct: 276 MEERKVNLHLPRFEVEDGYDLEAVLAAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSF 335
Query: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
V V EEGTEAAA TG T + G +HPFLF I H +N ILFFGRFSSP
Sbjct: 336 VAVTEEGTEAAAATGIGFTVTSAPGHENVHCNHPFLFFIRHNESNSILFFGRFSSP 391
>gi|92859634 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 7 [Homo sapiens]
Length = 380
Score = 252 bits (643), Expect = 5e-67
Identities = 143/415 (34%), Positives = 225/415 (54%), Gaps = 35/415 (8%)
Query: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
M L AN F NLF+ + N+F S S+ + +A+V +G++ + Q+ K+L
Sbjct: 1 MASLAAANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHV 60
Query: 61 NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
N T+ G+ + + + S + + S INAS +
Sbjct: 61 N---------------TASGYGNS------------SNSQSGLQSQLKRVFSDINASHKD 93
Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
Y L VN LF EK F ++YI +K Y ++ + VDF E+ R+ IN WV+ +T GK
Sbjct: 94 YDLSIVNGLFAEKVYGFHKDYIECAEKLYDAKVERVDFTNHLEDTRRNINKWVENETHGK 153
Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
I N++ EG + MVLVNAVYFKGKW++ F K F+ V MM+ K
Sbjct: 154 IKNVIGEGGISSSAVMVLVNAVYFKGKWQSAFTKSETINCHFKSPKCSGKAVAMMHQERK 213
Query: 241 LNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKM 300
N+ IED +ILEL Y G ++M++LLP+ L +E+++T+ L +WT+ +M
Sbjct: 214 FNLSVIEDPSMKILELRYNGGINMYVLLPE------NDLSEIENKLTFQNLMEWTNPRRM 267
Query: 301 AEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMV 360
VEV+ PQFK+E++YE++ LR++G++D F++ +A+ SG++ L++S + H++ +
Sbjct: 268 TSKYVEVFFPQFKIEKNYEMKQYLRALGLKDIFDESKADLSGIASGGRLYISRMMHKSYI 327
Query: 361 DVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
+V EEGTEA A TG + + F ADHPFLF+I + + ILF G+ S P
Sbjct: 328 EVTEEGTEATAATGSNIVEKQLPQSTLFRADHPFLFVI--RKDDIILFSGKVSCP 380
>gi|4505149 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 7 [Homo sapiens]
Length = 380
Score = 252 bits (643), Expect = 5e-67
Identities = 143/415 (34%), Positives = 225/415 (54%), Gaps = 35/415 (8%)
Query: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
M L AN F NLF+ + N+F S S+ + +A+V +G++ + Q+ K+L
Sbjct: 1 MASLAAANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHV 60
Query: 61 NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
N T+ G+ + + + S + + S INAS +
Sbjct: 61 N---------------TASGYGNS------------SNSQSGLQSQLKRVFSDINASHKD 93
Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
Y L VN LF EK F ++YI +K Y ++ + VDF E+ R+ IN WV+ +T GK
Sbjct: 94 YDLSIVNGLFAEKVYGFHKDYIECAEKLYDAKVERVDFTNHLEDTRRNINKWVENETHGK 153
Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
I N++ EG + MVLVNAVYFKGKW++ F K F+ V MM+ K
Sbjct: 154 IKNVIGEGGISSSAVMVLVNAVYFKGKWQSAFTKSETINCHFKSPKCSGKAVAMMHQERK 213
Query: 241 LNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKM 300
N+ IED +ILEL Y G ++M++LLP+ L +E+++T+ L +WT+ +M
Sbjct: 214 FNLSVIEDPSMKILELRYNGGINMYVLLPE------NDLSEIENKLTFQNLMEWTNPRRM 267
Query: 301 AEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMV 360
VEV+ PQFK+E++YE++ LR++G++D F++ +A+ SG++ L++S + H++ +
Sbjct: 268 TSKYVEVFFPQFKIEKNYEMKQYLRALGLKDIFDESKADLSGIASGGRLYISRMMHKSYI 327
Query: 361 DVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
+V EEGTEA A TG + + F ADHPFLF+I + + ILF G+ S P
Sbjct: 328 EVTEEGTEATAATGSNIVEKQLPQSTLFRADHPFLFVI--RKDDIILFSGKVSCP 380
>gi|167860126 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 5 [Homo sapiens]
Length = 375
Score = 240 bits (612), Expect = 2e-63
Identities = 130/416 (31%), Positives = 230/416 (55%), Gaps = 42/416 (10%)
Query: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
M+ L +AN+ FA++LFK L + P N+ SP +S+++++ +G++G T +++ +VL F
Sbjct: 1 MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHF 60
Query: 61 NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
V + F++++S +N +
Sbjct: 61 ENV-------------------------------------KDVPFGFQTVTSDVNKLSSF 83
Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
Y L+ + +L+ +KS + E+I ++ Y+ E + VDF + EE + +IN+ +K T G
Sbjct: 84 YSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKLEETKGQINNSIKDLTDGH 143
Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
N+L + SV+ T++++VNA YF GKW F + PFRVN PVQMM +
Sbjct: 144 FENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKECPFRVNKTDTKPVQMMNMEAT 203
Query: 241 LNIGYIEDLKAQILELPYAG-DVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
+G I+ + +I+ELP+ +SMF+LLP ++ D STGLE +E ++ + L++WT+
Sbjct: 204 FCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDESTGLEKIEKQLNSESLSQWTNPST 263
Query: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
MA +V++ IP+FK+E+ + ++ L ++G++ F++ ++FSGMSE + LS V H+
Sbjct: 264 MANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSEDTSDFSGMSETKGVALSNVIHKVC 323
Query: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
+++ E+G ++ G R + ADHPF+++I H T I+FFG+F SP
Sbjct: 324 LEITEDGGDSIEVPG----ARILQHKDELNADHPFIYIIRHNKTRNIIFFGKFCSP 375
>gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo
sapiens]
Length = 464
Score = 212 bits (539), Expect = 6e-55
Identities = 134/419 (31%), Positives = 222/419 (52%), Gaps = 45/419 (10%)
Query: 3 DLCVANTLFALNLFKHLAKA-SPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFN 61
+L AN+ FA ++HLA + + N+FLSP SIS+ AM +G+ T Q+ +V +F+
Sbjct: 82 ELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFD 141
Query: 62 EVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAI-NASTGN 120
+ + +D+IH F L+ + + +
Sbjct: 142 TISE--------------------------------KTSDQIHFFFAKLNCRLYRKANKS 169
Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
L S N+LFG+KS +F E Y + + Y ++ Q +DF E AE++R IN WV +T+G+
Sbjct: 170 SKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRAAINKWVSNKTEGR 229
Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
I +++P +++ T +VLVN +YFKG WK+ F + F + MMY K
Sbjct: 230 ITDVIPSEAINELTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSASMMYQEGK 289
Query: 241 LNIGYIEDLKAQILELPYAG-DVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
+ + Q+LELP+ G D++M L+LP L +E E+T + L +W D+
Sbjct: 290 FRYRRVAE-GTQVLELPFKGDDITMVLILPKP----EKSLAKVEKELTPEVLQEWL--DE 342
Query: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGM--SERNDLFLSEVFHQ 357
+ E + V++P+F++E+ + L+ L+ MG+ D F+ ++ G+ R+DL++S+ FH+
Sbjct: 343 LEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHK 402
Query: 358 AMVDVNEEGTEAAAGTGGVMTGRT-GHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
A ++VNEEG+EAAA T V+ GR+ F A+ PFL I N I+F GR ++P
Sbjct: 403 AFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANP 461
>gi|73623033 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform b [Homo sapiens]
Length = 242
Score = 197 bits (502), Expect = 1e-50
Identities = 109/277 (39%), Positives = 159/277 (57%), Gaps = 39/277 (14%)
Query: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
M+DLC AN FA++LFK L + ++N+F SP SISS +AMV+MG++GST QM++ L
Sbjct: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60
Query: 61 NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
+ G IH F+SL S +N +
Sbjct: 61 YKDG-------------------------------------DIHRGFQSLLSEVNRTGTQ 83
Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
YLL + N+LFGEK+ F ++ CQK+Y +E + + F E EE RK IN WV +T+GK
Sbjct: 84 YLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGK 143
Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
I +L G+VD T++VLVNA+YFKGKW F++K F+ N ++T VQMM+ K
Sbjct: 144 ISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTNEEKKT-VQMMFKEAK 202
Query: 241 LNIGYIEDLKAQILELPYA-GDVSMFLLLPDEIADVS 276
+GY +++ Q+LELPY ++SM +LLPD+ D++
Sbjct: 203 FKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLA 239
>gi|170295807 neuroserpin precursor [Homo sapiens]
Length = 410
Score = 195 bits (496), Expect = 6e-50
Identities = 116/411 (28%), Positives = 211/411 (51%), Gaps = 50/411 (12%)
Query: 12 ALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTPM 71
++N++ L +N+ SP SI+ M M+ +G++GST+ ++ + ++ +
Sbjct: 30 SVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSL-------- 81
Query: 72 TPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLFG 131
+N F+++ S+ + A Y+++ N LF
Sbjct: 82 --KNGEEFSFLKEF-------------------------SNMVTAKESQYVMKIANSLFV 114
Query: 132 EKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSVD 191
+ EE++++ +KY+++ VDF + A IN WV+ T + +L+ D
Sbjct: 115 QNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAVANY-INKWVENNTNNLVKDLVSPRDFD 173
Query: 192 GDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLKA 251
T + L+NAVYFKG WK+ F + + F + + MMY + + G D
Sbjct: 174 AATYLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSN 233
Query: 252 ------QILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDE 304
Q+LE+PY GD +SM L+L + ++T L+++++ + +W + K + +
Sbjct: 234 EAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEPLVKAQL----VEEWANSVK--KQK 287
Query: 305 VEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNE 364
VEVY+P+F +E+ +L+ +L+++G+ + F K AN +G+S+ ++FLS+ H++ ++VNE
Sbjct: 288 VEVYLPRFTVEQEIDLKDVLKALGITEIFIKD-ANLTGLSDNKEIFLSKAIHKSFLEVNE 346
Query: 365 EGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
EG+EAAA +G + R PQ + DHPF FLI ++ T ILF GR P
Sbjct: 347 EGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFLIRNRRTGTILFMGRVMHP 397
>gi|4826904 neuroserpin precursor [Homo sapiens]
Length = 410
Score = 195 bits (496), Expect = 6e-50
Identities = 116/411 (28%), Positives = 211/411 (51%), Gaps = 50/411 (12%)
Query: 12 ALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTPM 71
++N++ L +N+ SP SI+ M M+ +G++GST+ ++ + ++ +
Sbjct: 30 SVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSL-------- 81
Query: 72 TPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLFG 131
+N F+++ S+ + A Y+++ N LF
Sbjct: 82 --KNGEEFSFLKEF-------------------------SNMVTAKESQYVMKIANSLFV 114
Query: 132 EKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSVD 191
+ EE++++ +KY+++ VDF + A IN WV+ T + +L+ D
Sbjct: 115 QNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAVANY-INKWVENNTNNLVKDLVSPRDFD 173
Query: 192 GDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLKA 251
T + L+NAVYFKG WK+ F + + F + + MMY + + G D
Sbjct: 174 AATYLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSN 233
Query: 252 ------QILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDE 304
Q+LE+PY GD +SM L+L + ++T L+++++ + +W + K + +
Sbjct: 234 EAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEPLVKAQL----VEEWANSVK--KQK 287
Query: 305 VEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNE 364
VEVY+P+F +E+ +L+ +L+++G+ + F K AN +G+S+ ++FLS+ H++ ++VNE
Sbjct: 288 VEVYLPRFTVEQEIDLKDVLKALGITEIFIKD-ANLTGLSDNKEIFLSKAIHKSFLEVNE 346
Query: 365 EGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
EG+EAAA +G + R PQ + DHPF FLI ++ T ILF GR P
Sbjct: 347 EGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFLIRNRRTGTILFMGRVMHP 397
>gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member 2
[Homo sapiens]
Length = 405
Score = 189 bits (480), Expect = 4e-48
Identities = 122/411 (29%), Positives = 213/411 (51%), Gaps = 47/411 (11%)
Query: 8 NTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANA 67
NT FA++L++ ++ S N+ SP I+ + MV +G++G + Q+ + L+ E A
Sbjct: 26 NTEFAVDLYQEVS-LSHKDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGE 84
Query: 68 VTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVN 127
E F +S SAI+ + N
Sbjct: 85 ------EFFV-----------------------------LKSFFSAISEKKQEFTFNLAN 109
Query: 128 KLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPE 187
L+ ++ + +E+Y+ ++++ S + VDF + A+ + I++WV+ +T GKI ++
Sbjct: 110 ALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQD-AKACAEMISTWVERKTDGKIKDMFSG 168
Query: 188 GSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIE 247
TR+VLVNA+YFKG WK F K+ L F + + MM + GY
Sbjct: 169 EEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLINFTKKNGSTVKIPMMKALLRTKYGYFS 228
Query: 248 D--LKAQILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDE 304
+ L Q+LEL Y GD S+ ++LP E D+ E +E IT ++ KW S +M E+E
Sbjct: 229 ESSLNYQVLELSYKGDEFSLIIILPAEGMDI----EEVEKLITAQQILKWLS--EMQEEE 282
Query: 305 VEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNE 364
VE+ +P+FK+E+ + + +L S+ + + F+ G + SG+++ +++++S+V + ++NE
Sbjct: 283 VEISLPRFKVEQKVDFKDVLYSLNITEIFS-GGCDLSGITDSSEVYVSQVTQKVFFEINE 341
Query: 365 EGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
+G+EAA TG + QF+A+HPFLF++ H T ILF GR ++P
Sbjct: 342 DGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMKHNPTESILFMGRVTNP 392
>gi|110225347 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 9 isoform
A [Homo sapiens]
Length = 435
Score = 186 bits (473), Expect = 3e-47
Identities = 125/411 (30%), Positives = 212/411 (51%), Gaps = 47/411 (11%)
Query: 8 NTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANA 67
NT FA L++ L +P+QN+F SP S+S+++AM+ +G+ T+ Q+ + L FN
Sbjct: 66 NTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFN------ 119
Query: 68 VTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVN 127
TPE+ IH F+ L ++ + + L+ +
Sbjct: 120 -LTHTPES--------------------------AIHQGFQHLVHSLTVPSKDLTLKMGS 152
Query: 128 KLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPE 187
LF +K + ++ ++ Y +E + DF A+ +INS VK +T+GK+ +++
Sbjct: 153 ALFVKKELQLQANFLGNVKRLYEAEVFSTDFSN-PSIAQARINSHVKKKTQGKVVDIIQ- 210
Query: 188 GSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGL-YPFRVNSAQRTPVQMMYLREKLNIGYI 246
+D T MVLVN ++FK KW+ PF + +PF V V MM+ +E+ G
Sbjct: 211 -GLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVD 269
Query: 247 EDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVE 306
+L +L++ Y GD F +LP + + LE ++ L KW+ + + +E
Sbjct: 270 TELNCFVLQMDYKGDAVAFFVLPSK-----GKMRQLEQALSARTLRKWS--HSLQKRWIE 322
Query: 307 VYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNEEG 366
V+IP+F + Y L +IL MG+++ F+K A+FSG+++R+ L +S+ H+A++DV+EEG
Sbjct: 323 VFIPRFSISASYNLETILPKMGIQNVFDK-NADFSGIAKRDSLQVSKATHKAVLDVSEEG 381
Query: 367 TEAAAGTGGVMTGRTGHGGPQFVA--DHPFLFLIMHKITNCILFFGRFSSP 415
TEA A T R+ G F + FL +I +K T+ ILF G+ +P
Sbjct: 382 TEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENP 432
>gi|50659080 serpin peptidase inhibitor, clade A, member 3 precursor
[Homo sapiens]
Length = 423
Score = 183 bits (464), Expect = 3e-46
Identities = 128/417 (30%), Positives = 213/417 (51%), Gaps = 50/417 (11%)
Query: 4 LCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEV 63
L AN FA +L+K L +P +N+ SP SIS+ +A + +G+ +T ++ K L+FN
Sbjct: 49 LASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFN-- 106
Query: 64 GANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLL 123
L + +IH SF+ L +N S+ L
Sbjct: 107 -------------------------------LTETSEAEIHQSFQHLLRTLNQSSDELQL 135
Query: 124 ESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPN 183
N +F ++ S + + ++ Y SE A DF + A A+K IN +VK T+GKI +
Sbjct: 136 SMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAA-AKKLINDYVKNGTRGKITD 194
Query: 184 LLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNI 243
L+ + +D T MVLVN ++FK KW+ PF+ + F ++ + V MM L L I
Sbjct: 195 LIKD--LDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMSLHH-LTI 251
Query: 244 GYI--EDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMA 301
Y E+L ++EL Y G+ S +LPD+ +E +E+ + + L +W +D +
Sbjct: 252 PYFRDEELSCTVVELKYTGNASALFILPDQ-----DKMEEVEAMLLPETLKRW--RDSLE 304
Query: 302 EDEV-EVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMV 360
E+ E+Y+P+F + Y L IL +G+E+AF +A+ SG++ +L +S+V H+A++
Sbjct: 305 FREIGELYLPKFSISRDYNLNDILLQLGIEEAFTS-KADLSGITGARNLAVSQVVHKAVL 363
Query: 361 DVNEEGTEAAAGTGGVMTGRTGHGGPQFVA--DHPFLFLIMHKITNCILFFGRFSSP 415
DV EEGTEA+A T +T + + + + PFL +I+ T I F + ++P
Sbjct: 364 DVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNP 420
>gi|73858566 heparin cofactor II precursor [Homo sapiens]
Length = 499
Score = 180 bits (456), Expect = 2e-45
Identities = 129/421 (30%), Positives = 212/421 (50%), Gaps = 53/421 (12%)
Query: 1 MEDLCVANTLFALNLFKHLAKASPT-QNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQ 59
++ L + N FA NL++ L T N+F++P IS+ M M+ +G +G T +Q+ +L
Sbjct: 123 IQRLNILNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILH 182
Query: 60 FNE-VGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINAST 118
F + V A++ +T IH+ FR L+ +
Sbjct: 183 FKDFVNASSKYEITT-----------------------------IHNLFRKLTHRLFRRN 213
Query: 119 GNYLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTK 178
Y L SVN L+ +K ++ ++YY +E Q DF + A + K N+ + TK
Sbjct: 214 FGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQIADFSDPAFIS--KTNNHIMKLTK 271
Query: 179 GKIPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLR 238
G I + L ++D T+M+++N +YFKG W F ++ + FR+N + V MM +
Sbjct: 272 GLIKDALE--NIDPATQMMILNCIYFKGSWVNKFPVEMTHNHNFRLNEREVVKVSMMQTK 329
Query: 239 EKLNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKD 298
++L IL+L Y G +SM +++P ++ +G++ LE+++T + +W +
Sbjct: 330 GNFLAANDQELDCDILQLEYVGGISMLIVVPHKM----SGMKTLEAQLTPRVVERW--QK 383
Query: 299 KMAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERN---DLFLSEVF 355
M EV +P+FKLE++Y L L+ MG+ F+K N +G+S++ DLF
Sbjct: 384 SMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDK-NGNMAGISDQRIAIDLFK---- 438
Query: 356 HQAMVDVNEEGTEA-AAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSS 414
HQ + VNEEGT+A T G M T +F D PFLFLI T+C+LF GR ++
Sbjct: 439 HQGTITVNEEGTQATTVTTVGFMPLST---QVRFTVDRPFLFLIYEHRTSCLLFMGRVAN 495
Query: 415 P 415
P
Sbjct: 496 P 496
>gi|194018472 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 5 [Homo
sapiens]
Length = 406
Score = 179 bits (453), Expect = 5e-45
Identities = 122/423 (28%), Positives = 214/423 (50%), Gaps = 55/423 (13%)
Query: 1 MEDLCVANTL-------FALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQ 53
+EDL V T+ F +L++ LA A+P+Q++F SP SIS ++AM+ +G+ ST+ Q
Sbjct: 31 VEDLHVGATVAPSSRRDFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQ 90
Query: 54 MAKVLQFNEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSA 113
+ + L N LQ + ++H F+ L
Sbjct: 91 ILEGLGLN---------------------------------LQKSSEKELHRGFQQLLQE 117
Query: 114 INASTGNYLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWV 173
+N + L N LF + ++ ++ + Y ++ +F + A A K+IN +V
Sbjct: 118 LNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAG-AMKQINDYV 176
Query: 174 KTQTKGKIPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQ 233
QTKGKI +LL ++D + +++VN ++FK KW+T F K F V S V
Sbjct: 177 AKQTKGKIVDLLK--NLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVP 234
Query: 234 MMYLREKLNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNK 293
MM ++ + +L +++ +PY G+ + +LP E ++ +E+ ++ L K
Sbjct: 235 MMSREDQYHYLLDRNLSCRVVGVPYQGNATALFILPSE-----GKMQQVENGLSEKTLRK 289
Query: 294 WTSKDKMAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSE 353
W K + ++E+Y+P+F +E Y+L +L S+G+ + F A+ SG+S +++ +SE
Sbjct: 290 WLKMFK--KRQLELYLPKFSIEGSYQLEKVLPSLGISNVFT-SHADLSGISNHSNIQVSE 346
Query: 354 VFHQAMVDVNEEGTEAAAGTGGVMTGRTGH-GGPQFVADHPFLFLIMHKITNCILFFGRF 412
+ H+A+V+V+E GT AAA TG + T R+ + V + PFL I + N ILF G+
Sbjct: 347 MVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFI---VDNNILFLGKV 403
Query: 413 SSP 415
+ P
Sbjct: 404 NRP 406
>gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 174 bits (441), Expect = 1e-43
Identities = 120/405 (29%), Positives = 203/405 (50%), Gaps = 46/405 (11%)
Query: 11 FALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTP 70
FA +L++ LA S + N+F SP SI++ AM+ +G++ T D++ + L FN
Sbjct: 57 FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLT------- 109
Query: 71 MTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLF 130
P+A +IH F+ L +N L + N LF
Sbjct: 110 ------------------EIPEA--------QIHEGFQELLRTLNQPDSQLQLTTGNGLF 143
Query: 131 GEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSV 190
+ ++++ +K Y SE V+F + EEA+K+IN +V+ T+GKI +L+ E +
Sbjct: 144 LSEGLKLVDKFLEDVKKLYHSEAFTVNFGD-TEEAKKQINDYVEKGTQGKIVDLVKE--L 200
Query: 191 DGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLK 250
D DT LVN ++FKGKW+ PFE K F V+ V MM NI + + L
Sbjct: 201 DRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLS 260
Query: 251 AQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVEVYIP 310
+ +L + Y G+ + LPDE L+ LE+E+T+D + K+ + +++P
Sbjct: 261 SWVLLMKYLGNATAIFFLPDE-----GKLQHLENELTHDIITKFLENED--RRSASLHLP 313
Query: 311 QFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNEEGTEAA 370
+ + Y+L+S+L +G+ F+ G A+ SG++E L LS+ H+A++ ++E+GTEAA
Sbjct: 314 KLSITGTYDLKSVLGQLGITKVFSNG-ADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAA 372
Query: 371 AGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
+ P+ + PF+FL++ + T LF G+ +P
Sbjct: 373 GAM--FLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 174 bits (441), Expect = 1e-43
Identities = 120/405 (29%), Positives = 203/405 (50%), Gaps = 46/405 (11%)
Query: 11 FALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTP 70
FA +L++ LA S + N+F SP SI++ AM+ +G++ T D++ + L FN
Sbjct: 57 FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLT------- 109
Query: 71 MTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLF 130
P+A +IH F+ L +N L + N LF
Sbjct: 110 ------------------EIPEA--------QIHEGFQELLRTLNQPDSQLQLTTGNGLF 143
Query: 131 GEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSV 190
+ ++++ +K Y SE V+F + EEA+K+IN +V+ T+GKI +L+ E +
Sbjct: 144 LSEGLKLVDKFLEDVKKLYHSEAFTVNFGD-TEEAKKQINDYVEKGTQGKIVDLVKE--L 200
Query: 191 DGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLK 250
D DT LVN ++FKGKW+ PFE K F V+ V MM NI + + L
Sbjct: 201 DRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLS 260
Query: 251 AQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVEVYIP 310
+ +L + Y G+ + LPDE L+ LE+E+T+D + K+ + +++P
Sbjct: 261 SWVLLMKYLGNATAIFFLPDE-----GKLQHLENELTHDIITKFLENED--RRSASLHLP 313
Query: 311 QFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNEEGTEAA 370
+ + Y+L+S+L +G+ F+ G A+ SG++E L LS+ H+A++ ++E+GTEAA
Sbjct: 314 KLSITGTYDLKSVLGQLGITKVFSNG-ADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAA 372
Query: 371 AGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
+ P+ + PF+FL++ + T LF G+ +P
Sbjct: 373 GAM--FLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163538 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 174 bits (441), Expect = 1e-43
Identities = 120/405 (29%), Positives = 203/405 (50%), Gaps = 46/405 (11%)
Query: 11 FALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTP 70
FA +L++ LA S + N+F SP SI++ AM+ +G++ T D++ + L FN
Sbjct: 57 FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLT------- 109
Query: 71 MTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLF 130
P+A +IH F+ L +N L + N LF
Sbjct: 110 ------------------EIPEA--------QIHEGFQELLRTLNQPDSQLQLTTGNGLF 143
Query: 131 GEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSV 190
+ ++++ +K Y SE V+F + EEA+K+IN +V+ T+GKI +L+ E +
Sbjct: 144 LSEGLKLVDKFLEDVKKLYHSEAFTVNFGD-TEEAKKQINDYVEKGTQGKIVDLVKE--L 200
Query: 191 DGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLK 250
D DT LVN ++FKGKW+ PFE K F V+ V MM NI + + L
Sbjct: 201 DRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLS 260
Query: 251 AQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVEVYIP 310
+ +L + Y G+ + LPDE L+ LE+E+T+D + K+ + +++P
Sbjct: 261 SWVLLMKYLGNATAIFFLPDE-----GKLQHLENELTHDIITKFLENED--RRSASLHLP 313
Query: 311 QFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNEEGTEAA 370
+ + Y+L+S+L +G+ F+ G A+ SG++E L LS+ H+A++ ++E+GTEAA
Sbjct: 314 KLSITGTYDLKSVLGQLGITKVFSNG-ADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAA 372
Query: 371 AGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
+ P+ + PF+FL++ + T LF G+ +P
Sbjct: 373 GAM--FLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163536 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 174 bits (441), Expect = 1e-43
Identities = 120/405 (29%), Positives = 203/405 (50%), Gaps = 46/405 (11%)
Query: 11 FALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTP 70
FA +L++ LA S + N+F SP SI++ AM+ +G++ T D++ + L FN
Sbjct: 57 FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLT------- 109
Query: 71 MTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLF 130
P+A +IH F+ L +N L + N LF
Sbjct: 110 ------------------EIPEA--------QIHEGFQELLRTLNQPDSQLQLTTGNGLF 143
Query: 131 GEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSV 190
+ ++++ +K Y SE V+F + EEA+K+IN +V+ T+GKI +L+ E +
Sbjct: 144 LSEGLKLVDKFLEDVKKLYHSEAFTVNFGD-TEEAKKQINDYVEKGTQGKIVDLVKE--L 200
Query: 191 DGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLK 250
D DT LVN ++FKGKW+ PFE K F V+ V MM NI + + L
Sbjct: 201 DRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLS 260
Query: 251 AQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVEVYIP 310
+ +L + Y G+ + LPDE L+ LE+E+T+D + K+ + +++P
Sbjct: 261 SWVLLMKYLGNATAIFFLPDE-----GKLQHLENELTHDIITKFLENED--RRSASLHLP 313
Query: 311 QFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNEEGTEAA 370
+ + Y+L+S+L +G+ F+ G A+ SG++E L LS+ H+A++ ++E+GTEAA
Sbjct: 314 KLSITGTYDLKSVLGQLGITKVFSNG-ADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAA 372
Query: 371 AGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
+ P+ + PF+FL++ + T LF G+ +P
Sbjct: 373 GAM--FLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163534 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 174 bits (441), Expect = 1e-43
Identities = 120/405 (29%), Positives = 203/405 (50%), Gaps = 46/405 (11%)
Query: 11 FALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTP 70
FA +L++ LA S + N+F SP SI++ AM+ +G++ T D++ + L FN
Sbjct: 57 FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLT------- 109
Query: 71 MTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLF 130
P+A +IH F+ L +N L + N LF
Sbjct: 110 ------------------EIPEA--------QIHEGFQELLRTLNQPDSQLQLTTGNGLF 143
Query: 131 GEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSV 190
+ ++++ +K Y SE V+F + EEA+K+IN +V+ T+GKI +L+ E +
Sbjct: 144 LSEGLKLVDKFLEDVKKLYHSEAFTVNFGD-TEEAKKQINDYVEKGTQGKIVDLVKE--L 200
Query: 191 DGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLK 250
D DT LVN ++FKGKW+ PFE K F V+ V MM NI + + L
Sbjct: 201 DRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLS 260
Query: 251 AQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVEVYIP 310
+ +L + Y G+ + LPDE L+ LE+E+T+D + K+ + +++P
Sbjct: 261 SWVLLMKYLGNATAIFFLPDE-----GKLQHLENELTHDIITKFLENED--RRSASLHLP 313
Query: 311 QFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNEEGTEAA 370
+ + Y+L+S+L +G+ F+ G A+ SG++E L LS+ H+A++ ++E+GTEAA
Sbjct: 314 KLSITGTYDLKSVLGQLGITKVFSNG-ADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAA 372
Query: 371 AGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
+ P+ + PF+FL++ + T LF G+ +P
Sbjct: 373 GAM--FLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,675,209
Number of Sequences: 37866
Number of extensions: 605995
Number of successful extensions: 1738
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 1438
Number of HSP's gapped (non-prelim): 122
length of query: 415
length of database: 18,247,518
effective HSP length: 105
effective length of query: 310
effective length of database: 14,271,588
effective search space: 4424192280
effective search space used: 4424192280
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.