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Search of human proteins with 218931217
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|218931217 leucine rich repeat containing 61 [Homo sapiens]
(259 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|218931217 leucine rich repeat containing 61 [Homo sapiens] 525 e-149
gi|13027616 leucine rich repeat containing 61 [Homo sapiens] 525 e-149
gi|39930571 leucine rich repeat containing 56 [Homo sapiens] 58 7e-09
gi|117414162 sodium channel associated protein 2 isoform a [Homo... 54 1e-07
gi|66472382 nischarin [Homo sapiens] 49 6e-06
gi|24308207 leucine rich repeat containing 47 [Homo sapiens] 47 2e-05
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 47 2e-05
gi|4826651 hypothetical protein LOC755 [Homo sapiens] 46 4e-05
gi|21389483 leucine-rich repeats and guanylate kinase domain con... 46 4e-05
gi|153792305 leucine rich repeat containing 58 [Homo sapiens] 46 4e-05
gi|50593002 small nuclear ribonucleoprotein polypeptide A' [Homo... 45 5e-05
gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo sap... 45 8e-05
gi|30181233 leucine-rich repeats and calponin homology (CH) doma... 44 1e-04
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 44 2e-04
gi|31621309 leucine rich repeat containing 6 [Homo sapiens] 43 2e-04
gi|110825984 malignant fibrous histiocytoma amplified sequence 1... 42 4e-04
gi|194272228 leucine rich repeat containing 48 isoform b [Homo s... 42 5e-04
gi|194272226 leucine rich repeat containing 48 isoform b [Homo s... 42 5e-04
gi|194272224 leucine rich repeat containing 48 isoform a [Homo s... 42 5e-04
gi|194272222 leucine rich repeat containing 48 isoform a [Homo s... 42 5e-04
gi|55743114 leucine rich repeat containing 49 [Homo sapiens] 42 5e-04
gi|61966761 leucine rich repeat containing 26 [Homo sapiens] 42 7e-04
gi|33285015 leucine rich repeat containing 28 [Homo sapiens] 42 7e-04
gi|31377705 centrosomal protein 97kDa [Homo sapiens] 42 7e-04
gi|238908508 leucine-rich repeat and death domain-containing pro... 41 0.001
gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 41 0.001
gi|55770895 ERBB2 interacting protein isoform 7 [Homo sapiens] 41 0.001
gi|8923909 ERBB2 interacting protein isoform 2 [Homo sapiens] 41 0.001
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami... 40 0.002
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof... 40 0.002
>gi|218931217 leucine rich repeat containing 61 [Homo sapiens]
Length = 259
Score = 525 bits (1353), Expect = e-149
Identities = 259/259 (100%), Positives = 259/259 (100%)
Query: 1 MDPPAEKPGEAGGLQITPQLLKSRTGEFSLESILLLKLRGLGLADLGCLGECLGLEWLDL 60
MDPPAEKPGEAGGLQITPQLLKSRTGEFSLESILLLKLRGLGLADLGCLGECLGLEWLDL
Sbjct: 1 MDPPAEKPGEAGGLQITPQLLKSRTGEFSLESILLLKLRGLGLADLGCLGECLGLEWLDL 60
Query: 61 SGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLATCENLQSLNAAGNLLATPGQLQCLAG 120
SGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLATCENLQSLNAAGNLLATPGQLQCLAG
Sbjct: 61 SGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLATCENLQSLNAAGNLLATPGQLQCLAG 120
Query: 121 LPCLEYLRLRDPLARLSNPLCANPSYWAAVRELLPGLKVIDGERVIGRGSEFYQLCRDLD 180
LPCLEYLRLRDPLARLSNPLCANPSYWAAVRELLPGLKVIDGERVIGRGSEFYQLCRDLD
Sbjct: 121 LPCLEYLRLRDPLARLSNPLCANPSYWAAVRELLPGLKVIDGERVIGRGSEFYQLCRDLD 180
Query: 181 SSLRPSSSPGPRATEAQPWVEPGYWESWPSRSSSILEEACRQFQDTLQECWDLDRQASDS 240
SSLRPSSSPGPRATEAQPWVEPGYWESWPSRSSSILEEACRQFQDTLQECWDLDRQASDS
Sbjct: 181 SSLRPSSSPGPRATEAQPWVEPGYWESWPSRSSSILEEACRQFQDTLQECWDLDRQASDS 240
Query: 241 LAQAEQVLSSAGPTSSFVF 259
LAQAEQVLSSAGPTSSFVF
Sbjct: 241 LAQAEQVLSSAGPTSSFVF 259
>gi|13027616 leucine rich repeat containing 61 [Homo sapiens]
Length = 259
Score = 525 bits (1353), Expect = e-149
Identities = 259/259 (100%), Positives = 259/259 (100%)
Query: 1 MDPPAEKPGEAGGLQITPQLLKSRTGEFSLESILLLKLRGLGLADLGCLGECLGLEWLDL 60
MDPPAEKPGEAGGLQITPQLLKSRTGEFSLESILLLKLRGLGLADLGCLGECLGLEWLDL
Sbjct: 1 MDPPAEKPGEAGGLQITPQLLKSRTGEFSLESILLLKLRGLGLADLGCLGECLGLEWLDL 60
Query: 61 SGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLATCENLQSLNAAGNLLATPGQLQCLAG 120
SGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLATCENLQSLNAAGNLLATPGQLQCLAG
Sbjct: 61 SGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLATCENLQSLNAAGNLLATPGQLQCLAG 120
Query: 121 LPCLEYLRLRDPLARLSNPLCANPSYWAAVRELLPGLKVIDGERVIGRGSEFYQLCRDLD 180
LPCLEYLRLRDPLARLSNPLCANPSYWAAVRELLPGLKVIDGERVIGRGSEFYQLCRDLD
Sbjct: 121 LPCLEYLRLRDPLARLSNPLCANPSYWAAVRELLPGLKVIDGERVIGRGSEFYQLCRDLD 180
Query: 181 SSLRPSSSPGPRATEAQPWVEPGYWESWPSRSSSILEEACRQFQDTLQECWDLDRQASDS 240
SSLRPSSSPGPRATEAQPWVEPGYWESWPSRSSSILEEACRQFQDTLQECWDLDRQASDS
Sbjct: 181 SSLRPSSSPGPRATEAQPWVEPGYWESWPSRSSSILEEACRQFQDTLQECWDLDRQASDS 240
Query: 241 LAQAEQVLSSAGPTSSFVF 259
LAQAEQVLSSAGPTSSFVF
Sbjct: 241 LAQAEQVLSSAGPTSSFVF 259
>gi|39930571 leucine rich repeat containing 56 [Homo sapiens]
Length = 542
Score = 58.2 bits (139), Expect = 7e-09
Identities = 49/133 (36%), Positives = 66/133 (49%), Gaps = 7/133 (5%)
Query: 36 LKLRGLGLADLGCLGECLG-LEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLA 94
LKL G L L LG LG L+ L L+ L L +ASL L L S N ++ L PL
Sbjct: 98 LKLNGSHLGSLRDLGTSLGHLQVLWLARCGLADLDGIASLPALKELYASYNNISDLSPLC 157
Query: 95 TCENLQSLNAAGNLLATPGQLQCLAGLPCLEYLRLRDPLARL------SNPLCANPSYWA 148
E L+ L+ GN + GQ++ L P L L L L L +N + +Y A
Sbjct: 158 LLEQLEVLDLEGNSVEDLGQVRYLQLCPRLAMLTLEGNLVCLQPAPGPTNKVPRGYNYRA 217
Query: 149 AVRELLPGLKVID 161
VR+L+P L+V+D
Sbjct: 218 EVRKLIPQLQVLD 230
>gi|117414162 sodium channel associated protein 2 isoform a [Homo
sapiens]
Length = 1032
Score = 54.3 bits (129), Expect = 1e-07
Identities = 48/169 (28%), Positives = 74/169 (43%), Gaps = 30/169 (17%)
Query: 27 EFSLESIL-LLKLRGLGLADLGCLGECLGLEWLDLSGNALTHLGPLASLRQLAVLNVSNN 85
E SL+S L + L ++ + + L+ LDLS N ++ + L +L +L LN+S N
Sbjct: 38 ELSLDSTLHAVNLHCNNISKIEAIDHIWNLQHLDLSSNQISRIEGLNTLTKLCTLNLSCN 97
Query: 86 RLTGLEPLATCENLQSLNAAGN-------LLATPG--------------------QLQCL 118
+T +E L NL LN + N L+ G LQC+
Sbjct: 98 LITKVEGLEELINLTRLNVSYNHIDDLSGLIPLHGIKHKLRYIDLHSNRIDSIHHLLQCM 157
Query: 119 AGLPCLEYLRLRDPLARLSNPLCANPSYWAAVRELLPGLKVIDGERVIG 167
GL L L L NP+C P Y A + + LP L+++D + + G
Sbjct: 158 VGLHFLTNLILEKDGD--DNPVCRLPGYRAVILQTLPQLRILDCKNIFG 204
>gi|66472382 nischarin [Homo sapiens]
Length = 1504
Score = 48.5 bits (114), Expect = 6e-06
Identities = 38/115 (33%), Positives = 56/115 (48%), Gaps = 29/115 (25%)
Query: 55 LEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLAT-CENLQSLNAAGNLLATPG 113
+E+LDLS N L + L L L L++S N+L+ LE L T N+++LN AGNLL +
Sbjct: 312 IEFLDLSHNGLLVVDNLQHLYNLVHLDLSYNKLSSLEGLHTKLGNIKTLNLAGNLLESLS 371
Query: 114 ----------------------QLQCLAGLPCLEYLRLRDPLARLSNPLCANPSY 146
+++ + LPCLE++ L L+NPL P Y
Sbjct: 372 GLHKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHVSL------LNNPLSIIPDY 420
>gi|24308207 leucine rich repeat containing 47 [Homo sapiens]
Length = 583
Score = 47.0 bits (110), Expect = 2e-05
Identities = 47/117 (40%), Positives = 53/117 (45%), Gaps = 11/117 (9%)
Query: 34 LLLKLRGLGLADLGCLGECLGLEWLDLSGNALTHLGP--------LASLRQLAVLNVSNN 85
L+L+ LG LG L LDLSGNAL L P L QL LN+S N
Sbjct: 80 LVLRRNALGPGLSPELGPLPALRVLDLSGNALEALPPGQGLGPAEPPGLPQLQSLNLSGN 139
Query: 86 RLTGL-EPLATC-ENLQSLNAAGNLL-ATPGQLQCLAGLPCLEYLRLRDPLARLSNP 139
RL L LA C LQSLN GN L + P +L LP L L D R +P
Sbjct: 140 RLRELPADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLLSELAAADNCLRELSP 196
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 46.6 bits (109), Expect = 2e-05
Identities = 36/102 (35%), Positives = 52/102 (50%), Gaps = 5/102 (4%)
Query: 11 AGGLQITPQLLKSRTGEFSLESILLLKLR-----GLGLADLGCLGECLGLEWLDLSGNAL 65
AG IT L+K T + +L I L L G + L +C+ LE L+LS N +
Sbjct: 78 AGVRYITEALIKKLTKQDNLALIKSLNLSLSKDGGKKFKYIENLEKCVKLEVLNLSYNLI 137
Query: 66 THLGPLASLRQLAVLNVSNNRLTGLEPLATCENLQSLNAAGN 107
+ L L +L LN+S N+++ +E + NLQ LN AGN
Sbjct: 138 GKIEKLDKLLKLRELNLSYNKISKIEGIENMCNLQKLNLAGN 179
>gi|4826651 hypothetical protein LOC755 [Homo sapiens]
Length = 256
Score = 45.8 bits (107), Expect = 4e-05
Identities = 33/110 (30%), Positives = 51/110 (46%), Gaps = 8/110 (7%)
Query: 58 LDLSGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLATCENLQSLNAAGNLLATPGQLQC 117
L+ G+ LT + + L V+ +S N ++ LEP++ C+ L L N + + +L
Sbjct: 23 LNCWGSRLTDISICQEMPSLEVITLSVNSISTLEPVSRCQRLSELYLRRNRIPSLAELFY 82
Query: 118 LAGLPCLEYLRLRDPLARLSNPLCANP--SYWAAVRELLPGLKVIDGERV 165
L GLP L L L + NP C Y V LP L+ +D + V
Sbjct: 83 LKGLPRLRVLWLAE------NPCCGTSPHRYRMTVLRTLPRLQKLDNQAV 126
>gi|21389483 leucine-rich repeats and guanylate kinase domain
containing [Homo sapiens]
Length = 825
Score = 45.8 bits (107), Expect = 4e-05
Identities = 31/113 (27%), Positives = 57/113 (50%), Gaps = 6/113 (5%)
Query: 53 LGLEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLATCENLQSLNAAGNLLATP 112
L ++ L LS N + + L L+ L L++S+N+++ L+ L + L+ +N N +A
Sbjct: 258 LPIKILCLSNNQIEMITGLEDLKALQNLDLSHNQISSLQGLENHDLLEVINLEDNKIAEL 317
Query: 113 GQLQCLAGLPCLEYLRLRDPLARLSNPLCANPSYWAAVRELLPGLKVIDGERV 165
+++ + LP L L L L NP+ YW V +L L +D +++
Sbjct: 318 REIEYIKNLPILRVLNL------LENPIQEKSEYWFFVIFMLLRLTELDQKKI 364
Score = 37.0 bits (84), Expect = 0.017
Identities = 26/87 (29%), Positives = 42/87 (48%)
Query: 24 RTGEFSLESILLLKLRGLGLADLGCLGECLGLEWLDLSGNALTHLGPLASLRQLAVLNVS 83
R+G + + L L L G L D+ L + L+ LDLS N + L ++ + L LN S
Sbjct: 120 RSGSGTEQVYLNLTLSGCNLIDVSILCGYVHLQKLDLSANKIEDLSCVSCMPYLLELNAS 179
Query: 84 NNRLTGLEPLATCENLQSLNAAGNLLA 110
N LT +NL+ + + N ++
Sbjct: 180 QNNLTTFFNFKPPKNLKKADFSHNQIS 206
Score = 31.2 bits (69), Expect = 0.94
Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 1/66 (1%)
Query: 49 LGECLGLEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLATCENLQSLNAAGNL 108
L + L+ LDLS N ++ L L + L V+N+ +N++ L + +NL L NL
Sbjct: 276 LEDLKALQNLDLSHNQISSLQGLENHDLLEVINLEDNKIAELREIEYIKNLPILRVL-NL 334
Query: 109 LATPGQ 114
L P Q
Sbjct: 335 LENPIQ 340
>gi|153792305 leucine rich repeat containing 58 [Homo sapiens]
Length = 371
Score = 45.8 bits (107), Expect = 4e-05
Identities = 30/61 (49%), Positives = 35/61 (57%), Gaps = 8/61 (13%)
Query: 55 LEWLDLSGNALTHLGP-LASLRQLAVLNVSNNRL-------TGLEPLATCENLQSLNAAG 106
L+ LD+SGNALT LGP L +LR L L NNRL GL C +LQ LN +G
Sbjct: 70 LQLLDVSGNALTALGPELLALRGLRTLLAKNNRLGGPSALPKGLAQSPLCRSLQVLNLSG 129
Query: 107 N 107
N
Sbjct: 130 N 130
>gi|50593002 small nuclear ribonucleoprotein polypeptide A' [Homo
sapiens]
Length = 255
Score = 45.4 bits (106), Expect = 5e-05
Identities = 43/135 (31%), Positives = 60/135 (44%), Gaps = 13/135 (9%)
Query: 36 LKLRGLGLADLGCLGECLG-LEWLDLSGNALTHLGPLASLRQLAVLNVSNNRL----TGL 90
L LRG + + LG L + +D S N + L LR+L L V+NNR+ GL
Sbjct: 24 LDLRGYKIPVIENLGATLDQFDAIDFSDNEIRKLDGFPLLRRLKTLLVNNNRICRIGEGL 83
Query: 91 EPLATCENLQSLNAAGNLLATPGQLQCLAGLPCLEYLRLRDPLARLSNPLCANPSYWAAV 150
+ C L L N L G L LA L L YL + L NP+ Y V
Sbjct: 84 DQALPC--LTELILTNNSLVELGDLDPLASLKSLTYLSI------LRNPVTNKKHYRLYV 135
Query: 151 RELLPGLKVIDGERV 165
+P ++V+D ++V
Sbjct: 136 IYKVPQVRVLDFQKV 150
>gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo
sapiens]
Length = 360
Score = 44.7 bits (104), Expect = 8e-05
Identities = 36/133 (27%), Positives = 62/133 (46%), Gaps = 6/133 (4%)
Query: 29 SLESILLLKLRGLGLADLGCLGECLGLEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLT 88
+L ++ +L ++ L + L + L L LS N + + L + +L +L++++NR+
Sbjct: 228 ALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVIEGLENNNKLTMLDIASNRIK 287
Query: 89 GLEPLATCENLQSLNAAGNLLATPGQLQCLAGLPCLEYLRLRDPLARLSNPLCANPSYWA 148
+E ++ LQ NLL + L L G LE + L NPL +P Y
Sbjct: 288 KIENISHLTELQEFWMNDNLLESWSDLDELKGARSLETVYLE------RNPLQKDPQYRR 341
Query: 149 AVRELLPGLKVID 161
V LP ++ ID
Sbjct: 342 KVMLALPSVRQID 354
Score = 37.0 bits (84), Expect = 0.017
Identities = 25/79 (31%), Positives = 40/79 (50%)
Query: 29 SLESILLLKLRGLGLADLGCLGECLGLEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLT 88
+L + +L+L + + + LE L L N +T L L +L L VL++ +NRLT
Sbjct: 184 NLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLT 243
Query: 89 GLEPLATCENLQSLNAAGN 107
+E L NL+ L + N
Sbjct: 244 KIEGLQNLVNLRELYLSHN 262
Score = 36.6 bits (83), Expect = 0.022
Identities = 22/70 (31%), Positives = 36/70 (51%)
Query: 55 LEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLATCENLQSLNAAGNLLATPGQ 114
L+ L L N ++ + L++L QL +L + +NR+ +E + T NL+SL N +
Sbjct: 166 LKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQN 225
Query: 115 LQCLAGLPCL 124
L L L L
Sbjct: 226 LDALTNLTVL 235
Score = 34.3 bits (77), Expect = 0.11
Identities = 29/111 (26%), Positives = 48/111 (43%)
Query: 14 LQITPQLLKSRTGEFSLESILLLKLRGLGLADLGCLGECLGLEWLDLSGNALTHLGPLAS 73
L + L+K L+S+ L L + + L LE LD+S N L ++ +
Sbjct: 103 LCLRQNLIKCIENLEELQSLRELDLYDNQIKKIENLEALTELEILDISFNLLRNIEGVDK 162
Query: 74 LRQLAVLNVSNNRLTGLEPLATCENLQSLNAAGNLLATPGQLQCLAGLPCL 124
L +L L + NN+++ +E L+ LQ L N + + L L L
Sbjct: 163 LTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRAIENIDTLTNLESL 213
>gi|30181233 leucine-rich repeats and calponin homology (CH) domain
containing 4 [Homo sapiens]
Length = 683
Score = 44.3 bits (103), Expect = 1e-04
Identities = 43/119 (36%), Positives = 59/119 (49%), Gaps = 11/119 (9%)
Query: 20 LLKSRTGEFSLESILLLKLRGLGLAD--LGCLGECLG----LEWLDLSGNALTHLGPLAS 73
L ++R E + L+ L GL L L CL LG L +L+LS N L+ L P
Sbjct: 75 LSRNRFPEVPEAACQLVSLEGLSLYHNCLRCLNPALGNLTALTYLNLSRNQLSLLPPYIC 134
Query: 74 LRQLAVLNVSNNRLTGLEP-LATCENLQSLNAAGN-LLATPGQLQCLAGLPCLEYLRLR 130
L VL VSNN+L L P + T +L+ L+ + N L + P + L GL L L +R
Sbjct: 135 QLPLRVLIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSLPSE---LCGLSSLRDLNVR 190
>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member B [Homo sapiens]
Length = 251
Score = 43.5 bits (101), Expect = 2e-04
Identities = 41/118 (34%), Positives = 55/118 (46%), Gaps = 8/118 (6%)
Query: 47 GCLGECLGLEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLTG-LEPLAT-CENLQSLNA 104
G E + LE+L L L + L L +L L +S NR+ G L+ LA NL LN
Sbjct: 36 GLTAEFVNLEFLSLINVGLISVSNLPKLPKLKKLELSENRIFGGLDMLAEKLPNLTHLNL 95
Query: 105 AGNLLATPGQLQCLAGLPCLEYLRLRDPLARLSNPLCANPSYWAAVRELLPGLKVIDG 162
+GN L L+ L L CL+ L L + N Y +V +LLP L +DG
Sbjct: 96 SGNKLKDISTLEPLKKLECLKSLDLFNCEVTNLN------DYRESVFKLLPQLTYLDG 147
>gi|31621309 leucine rich repeat containing 6 [Homo sapiens]
Length = 466
Score = 43.1 bits (100), Expect = 2e-04
Identities = 32/114 (28%), Positives = 54/114 (47%), Gaps = 6/114 (5%)
Query: 52 CLGLEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLATCENLQSLNAAGNLLAT 111
C L+ L L N + + ++ L++L LN++ N + +E L CE L L+ N +
Sbjct: 43 CRDLKILYLQNNLIGKIENVSKLKKLEYLNLALNNIEKIENLEGCEELAKLDLTVNFI-- 100
Query: 112 PGQLQCLAGLPCLEYLRLRDPLARLSNPLCANPSYWAAVRELLPGLKVIDGERV 165
G+L + L +L+ L + NP + Y V LP LK +DG+ +
Sbjct: 101 -GELSSIKNLQHNIHLK---ELFLMGNPCASFDHYREFVVATLPQLKWLDGKEI 150
>gi|110825984 malignant fibrous histiocytoma amplified sequence 1
[Homo sapiens]
Length = 1052
Score = 42.4 bits (98), Expect = 4e-04
Identities = 44/119 (36%), Positives = 62/119 (52%), Gaps = 11/119 (9%)
Query: 13 GLQITPQLLKSRTGEFSLESILLLKLRGLGLADLGCLGECLG--LEWLDLSGNALTHLGP 70
GL+ P+ L S G S+ +L LR A L LG L LD+S N LT LG
Sbjct: 74 GLEEVPEGLGSALG-----SLRVLVLRRNRFARLPPAVAELGHHLTELDVSHNRLTALGA 128
Query: 71 --LASLRQLAVLNVSNNRLTGL-EPLATCENLQSLNAAGNLLA-TPGQLQCLAGLPCLE 125
+++LR+L LN+S+N+L L L +L+ L+ + N LA P L CL+ L L+
Sbjct: 129 EVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSLSCLSRLRTLD 187
>gi|194272228 leucine rich repeat containing 48 isoform b [Homo
sapiens]
Length = 457
Score = 42.0 bits (97), Expect = 5e-04
Identities = 32/111 (28%), Positives = 48/111 (43%), Gaps = 6/111 (5%)
Query: 55 LEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLATCENLQSLNAAGNLLATPGQ 114
L WLDLS N + + L +L L L++ NNR++ ++ L LQ L+ N +
Sbjct: 89 LVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMN 148
Query: 115 LQCLAGLPCLEYLRLRDPLARLSNPLCANPSYWAAVRELLPGLKVIDGERV 165
+ L CL L L NP+ Y + LP L +D R+
Sbjct: 149 IIYLRRFKCLRTLSLS------RNPISEAEDYKMFICAYLPDLMYLDYRRI 193
>gi|194272226 leucine rich repeat containing 48 isoform b [Homo
sapiens]
Length = 457
Score = 42.0 bits (97), Expect = 5e-04
Identities = 32/111 (28%), Positives = 48/111 (43%), Gaps = 6/111 (5%)
Query: 55 LEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLATCENLQSLNAAGNLLATPGQ 114
L WLDLS N + + L +L L L++ NNR++ ++ L LQ L+ N +
Sbjct: 89 LVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMN 148
Query: 115 LQCLAGLPCLEYLRLRDPLARLSNPLCANPSYWAAVRELLPGLKVIDGERV 165
+ L CL L L NP+ Y + LP L +D R+
Sbjct: 149 IIYLRRFKCLRTLSLS------RNPISEAEDYKMFICAYLPDLMYLDYRRI 193
>gi|194272224 leucine rich repeat containing 48 isoform a [Homo
sapiens]
Length = 523
Score = 42.0 bits (97), Expect = 5e-04
Identities = 32/111 (28%), Positives = 48/111 (43%), Gaps = 6/111 (5%)
Query: 55 LEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLATCENLQSLNAAGNLLATPGQ 114
L WLDLS N + + L +L L L++ NNR++ ++ L LQ L+ N +
Sbjct: 89 LVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMN 148
Query: 115 LQCLAGLPCLEYLRLRDPLARLSNPLCANPSYWAAVRELLPGLKVIDGERV 165
+ L CL L L NP+ Y + LP L +D R+
Sbjct: 149 IIYLRRFKCLRTLSLS------RNPISEAEDYKMFICAYLPDLMYLDYRRI 193
>gi|194272222 leucine rich repeat containing 48 isoform a [Homo
sapiens]
Length = 523
Score = 42.0 bits (97), Expect = 5e-04
Identities = 32/111 (28%), Positives = 48/111 (43%), Gaps = 6/111 (5%)
Query: 55 LEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLATCENLQSLNAAGNLLATPGQ 114
L WLDLS N + + L +L L L++ NNR++ ++ L LQ L+ N +
Sbjct: 89 LVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMN 148
Query: 115 LQCLAGLPCLEYLRLRDPLARLSNPLCANPSYWAAVRELLPGLKVIDGERV 165
+ L CL L L NP+ Y + LP L +D R+
Sbjct: 149 IIYLRRFKCLRTLSLS------RNPISEAEDYKMFICAYLPDLMYLDYRRI 193
>gi|55743114 leucine rich repeat containing 49 [Homo sapiens]
Length = 686
Score = 42.0 bits (97), Expect = 5e-04
Identities = 49/225 (21%), Positives = 90/225 (40%), Gaps = 29/225 (12%)
Query: 29 SLESILLLKLRGLGLADLGCLGECLGLEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLT 88
+L+S+ +L L G + + + L L+L+ N L+H+ L L L LN+ +N++T
Sbjct: 176 NLKSLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQIT 235
Query: 89 GLEPLATCENLQSLNAAGNLLATPGQLQCLAGLPCLEYLRLRDPLARLSNPLCANPSYWA 148
+ + LQ L + N +++ + CLA L + NP+ Y
Sbjct: 236 FVRDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFD------GNPIAQESWYKH 289
Query: 149 AVRELLPGLKVIDGERVIGRGSEFYQLCRDLDSSLRPSSSPGPRATEAQPWVEPGYWESW 208
V + + L+ +D +R+ + R +S + E +
Sbjct: 290 TVLQNMMQLRQLDMKRI-------------TEEERRMASVLAKKEEE----------KKR 326
Query: 209 PSRSSSILEEACRQFQDTLQECWDLDRQASDSLAQAEQVLSSAGP 253
S S+L+E R + + WDL +Q ++A E S P
Sbjct: 327 ESHKQSLLKEKKRLTINNVARQWDLQQQRVANIATNEDRKDSDSP 371
>gi|61966761 leucine rich repeat containing 26 [Homo sapiens]
Length = 334
Score = 41.6 bits (96), Expect = 7e-04
Identities = 36/82 (43%), Positives = 43/82 (52%), Gaps = 9/82 (10%)
Query: 55 LEWLDLSGNALTHLGP--LASLRQLAVLNVSNNRLTGLEP--LATCENLQSLNAAGNLLA 110
L+ LDLS N L L P A LR L L+++ NRL LEP L L+SL+ N LA
Sbjct: 121 LQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELA 180
Query: 111 --TPGQLQCLAGLPCLEYLRLR 130
PG L LP L+ L LR
Sbjct: 181 ALAPG---LLGRLPALDALHLR 199
>gi|33285015 leucine rich repeat containing 28 [Homo sapiens]
Length = 367
Score = 41.6 bits (96), Expect = 7e-04
Identities = 50/147 (34%), Positives = 70/147 (47%), Gaps = 18/147 (12%)
Query: 13 GLQITPQLLKSRTGEFSLESILLLKLRGLGLADLG---------CLGECLGLEWLDLSGN 63
GLQ +L R SL L KL L L +G + L+ LDLS N
Sbjct: 39 GLQYLERLYMKRNSLTSLPENLAQKLPNLVELYLHSNNIVVVPEAIGSLVKLQCLDLSDN 98
Query: 64 ALTHLGP-LASLRQLAVLNVSNNRLTGLEP-LATCENLQSLNAAGN-LLATPGQL-QCLA 119
AL + P + LR L L ++NN+L L P + + LQ+L+ + N LL P +L CL+
Sbjct: 99 ALEIVCPEIGRLRALRHLRLANNQLQFLPPEVGDLKELQTLDISTNRLLTLPERLHMCLS 158
Query: 120 GLPCLEYLRL-RDPLARLSNPLCANPS 145
L+YL + R+ L + LC PS
Sbjct: 159 ----LQYLTVDRNRLWYVPRHLCQLPS 181
>gi|31377705 centrosomal protein 97kDa [Homo sapiens]
Length = 865
Score = 41.6 bits (96), Expect = 7e-04
Identities = 25/82 (30%), Positives = 47/82 (57%), Gaps = 3/82 (3%)
Query: 33 ILLLKLRGLGLADLGC---LGECLGLEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLTG 89
+ LL++ L +GC L E + LEWL+L+GN L + + S L L++S+N ++
Sbjct: 79 LTLLRVLNLPHNSIGCVEGLKELVHLEWLNLAGNNLKAMEQINSCTALQHLDLSDNNISQ 138
Query: 90 LEPLATCENLQSLNAAGNLLAT 111
+ L+ +L++L GN++ +
Sbjct: 139 IGDLSKLVSLKTLLLHGNIITS 160
Score = 37.0 bits (84), Expect = 0.017
Identities = 25/77 (32%), Positives = 38/77 (49%)
Query: 49 LGECLGLEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLATCENLQSLNAAGNL 108
L +C L L ++ N L + +A L L VLN+ +N + +E L +L+ LN AGN
Sbjct: 54 LEKCKRLIQLSVANNRLVRMMGVAKLTLLRVLNLPHNSIGCVEGLKELVHLEWLNLAGNN 113
Query: 109 LATPGQLQCLAGLPCLE 125
L Q+ L L+
Sbjct: 114 LKAMEQINSCTALQHLD 130
Score = 31.2 bits (69), Expect = 0.94
Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 4/91 (4%)
Query: 40 GLGLADLGCLGEC-LGLEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLATCEN 98
G GL LG C + L L N + L L ++L L+V+NNRL + +A
Sbjct: 22 GQGLQKLGPNLPCEADIHTLILDKNQIIKLENLEKCKRLIQLSVANNRLVRMMGVAKLTL 81
Query: 99 LQSLNAAGNLLATPGQLQCLAGLPCLEYLRL 129
L+ LN N + G ++ L L LE+L L
Sbjct: 82 LRVLNLPHNSI---GCVEGLKELVHLEWLNL 109
>gi|238908508 leucine-rich repeat and death domain-containing
protein [Homo sapiens]
Length = 860
Score = 41.2 bits (95), Expect = 0.001
Identities = 35/85 (41%), Positives = 47/85 (55%), Gaps = 8/85 (9%)
Query: 44 ADLGCLGECLGLEWLDLSGNALTHL-GPLASLRQLAVLNVSNNRLTGLEPLATC--ENLQ 100
+DL CLG LE L L N L H+ L SL+ L VLN+ N+LT P A C L
Sbjct: 251 SDLECLGN---LEILSLGKNKLRHIPDTLPSLKTLRVLNLEYNQLTTF-PKALCFLPKLI 306
Query: 101 SLNAAGNLLAT-PGQLQCLAGLPCL 124
SL+ GNL+++ P +++ L L L
Sbjct: 307 SLDLTGNLISSLPKEIRELKNLETL 331
>gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member A [Homo sapiens]
Length = 249
Score = 41.2 bits (95), Expect = 0.001
Identities = 43/119 (36%), Positives = 56/119 (47%), Gaps = 10/119 (8%)
Query: 47 GCLGECLGLEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLTG-LEPLAT-CENLQSLNA 104
G E LE+L LT + L L +L L +S+NR++G LE LA C NL LN
Sbjct: 36 GLTDEFEELEFLSTINVGLTSIANLPKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNL 95
Query: 105 AGNLLATPGQLQCLAGLPCLEYLRLRDPLARLSNPLCAN-PSYWAAVRELLPGLKVIDG 162
+GN + L + L LE L+ D L N N Y V +LLP L +DG
Sbjct: 96 SGNKIK---DLSTIEPLKKLENLKSLD----LFNCEVTNLNDYRENVFKLLPQLTYLDG 147
>gi|55770895 ERBB2 interacting protein isoform 7 [Homo sapiens]
Length = 1302
Score = 40.8 bits (94), Expect = 0.001
Identities = 33/102 (32%), Positives = 51/102 (50%), Gaps = 11/102 (10%)
Query: 19 QLLKSRTGEFSLESILLLKLRGLGLADLGC---------LGECLGLEWLDLSGNALTHL- 68
Q+L+ R + + + +L L DLG L + GL+ + N LT +
Sbjct: 164 QILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIP 223
Query: 69 GPLASLRQLAVLNVSNNRLTGLEP-LATCENLQSLNAAGNLL 109
G + SL+QL L+VS N + +E ++TCENLQ L + N L
Sbjct: 224 GFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSL 265
>gi|8923909 ERBB2 interacting protein isoform 2 [Homo sapiens]
Length = 1371
Score = 40.8 bits (94), Expect = 0.001
Identities = 33/102 (32%), Positives = 51/102 (50%), Gaps = 11/102 (10%)
Query: 19 QLLKSRTGEFSLESILLLKLRGLGLADLGC---------LGECLGLEWLDLSGNALTHL- 68
Q+L+ R + + + +L L DLG L + GL+ + N LT +
Sbjct: 164 QILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIP 223
Query: 69 GPLASLRQLAVLNVSNNRLTGLEP-LATCENLQSLNAAGNLL 109
G + SL+QL L+VS N + +E ++TCENLQ L + N L
Sbjct: 224 GFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSL 265
>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member E isoform 1 [Homo sapiens]
Length = 268
Score = 40.4 bits (93), Expect = 0.002
Identities = 35/110 (31%), Positives = 55/110 (50%), Gaps = 8/110 (7%)
Query: 55 LEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLTG-LEPLAT-CENLQSLNAAGNLLATP 112
LE+L ++ L+ L L SL +L L +S+N ++G LE LA C NL LN +GN +
Sbjct: 44 LEFLSMANVELSSLARLPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDL 103
Query: 113 GQLQCLAGLPCLEYLRLRDPLARLSNPLCANPSYWAAVRELLPGLKVIDG 162
++ L L L+ L L + + Y ++ ELL + +DG
Sbjct: 104 STVEALQNLKNLKSLDL------FNCEITNLEDYRESIFELLQQITYLDG 147
>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform
1 [Homo sapiens]
Length = 1722
Score = 40.4 bits (93), Expect = 0.002
Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Query: 32 SILLLKLRGLGLADLGCLGECLGLEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLTGLE 91
++ L LR GL L L C L+++D N + + +L L V+ ++ N+LT L
Sbjct: 819 NLQFLSLRRCGLTSLHSLSNCKKLKYIDAQENHIEAI-ECENLENLCVVLLNKNQLTSLH 877
Query: 92 PLATCENLQSLNAAGNLLATPG 113
L C N+Q L + N + G
Sbjct: 878 GLDGCTNIQCLELSYNKITRIG 899
Score = 39.3 bits (90), Expect = 0.003
Identities = 34/139 (24%), Positives = 68/139 (48%), Gaps = 8/139 (5%)
Query: 35 LLKLRGLGLADLGCLGECLGLEWLDLSGNALTHLGPLAS--LRQLAVLNVSNNRLTGLEP 92
+LKL+G L++L L + L L L N+++ + +S L L + +S N LT + P
Sbjct: 1017 ILKLQGNYLSELPSLENLVLLRELHLDDNSISTVEAFSSYWLPLLQNITISQNSLTKIVP 1076
Query: 93 LATCENLQSLNAAGNLLATPGQLQCLAGLPCLEYLRLRDPLARLSNPLCANPSYWAAVRE 152
L +L+ L+ + N L+ + + + L+ NPL ++ ++ +
Sbjct: 1077 LFHFVSLEKLDVSHNCLS-----DLKSAIKWFDACYSLHELSLTGNPLLQETNWRDSLLK 1131
Query: 153 LLPGLKVIDGERVIGRGSE 171
+LP L++++G ++ SE
Sbjct: 1132 VLPALRILNG-NILNSNSE 1149
Score = 34.3 bits (77), Expect = 0.11
Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 6/93 (6%)
Query: 55 LEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLATCENLQSLNAAGNLLATPGQ 114
L+ L L N L + L + L+ S+N LT +E + C LQ L GN L+ +
Sbjct: 971 LQQLILDHNQLINTKGLCDTPTIVYLDCSHNHLTDVEGVENCGLLQILKLQGNYLS---E 1027
Query: 115 LQCLAGLPCLEYLRLRDPLARLSNPLCANPSYW 147
L L L L L L D + + A SYW
Sbjct: 1028 LPSLENLVLLRELHLDD---NSISTVEAFSSYW 1057
Score = 31.6 bits (70), Expect = 0.72
Identities = 35/111 (31%), Positives = 50/111 (45%), Gaps = 13/111 (11%)
Query: 29 SLESILLLKLRGLGLADLGCLGECLGLEWLDL------SGNALTHLGPLASLRQLAVLNV 82
SLE+++LL+ L + + E WL L S N+LT + PL L L+V
Sbjct: 1030 SLENLVLLRELHLDDNSISTV-EAFSSYWLPLLQNITISQNSLTKIVPLFHFVSLEKLDV 1088
Query: 83 SNNRLTGLEP----LATCENLQSLNAAGN--LLATPGQLQCLAGLPCLEYL 127
S+N L+ L+ C +L L+ GN L T + L LP L L
Sbjct: 1089 SHNCLSDLKSAIKWFDACYSLHELSLTGNPLLQETNWRDSLLKVLPALRIL 1139
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,221,298
Number of Sequences: 37866
Number of extensions: 511251
Number of successful extensions: 1929
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 102
Number of HSP's that attempted gapping in prelim test: 1773
Number of HSP's gapped (non-prelim): 245
length of query: 259
length of database: 18,247,518
effective HSP length: 100
effective length of query: 159
effective length of database: 14,460,918
effective search space: 2299285962
effective search space used: 2299285962
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.