Search of human proteins with 216547769

Search of human proteins with 216547769

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|216547769 SH2 domain containing 3C isoform c [Homo sapiens]
         (506 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|216547801 SH2 domain containing 3C isoform e [Homo sapiens]       1011   0.0  
gi|216547790 SH2 domain containing 3C isoform d [Homo sapiens]       1011   0.0  
gi|216547779 SH2 domain containing 3C isoform c [Homo sapiens]       1011   0.0  
gi|216547769 SH2 domain containing 3C isoform c [Homo sapiens]       1011   0.0  
gi|216547763 SH2 domain containing 3C isoform b [Homo sapiens]       1011   0.0  
gi|41281821 SH2 domain containing 3C isoform a [Homo sapiens]        1011   0.0  
gi|4502371 breast cancer antiestrogen resistance 3 [Homo sapiens]     347   2e-95
gi|208609985 SH2 domain containing 3A [Homo sapiens]                  255   8e-68
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             45   2e-04
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             44   5e-04
gi|148747862 Rap guanine nucleotide exchange factor 3 isoform b ...    43   8e-04
gi|20070215 Rap guanine nucleotide exchange factor 3 isoform b [...    43   8e-04
gi|148747859 Rap guanine nucleotide exchange factor 3 isoform a ...    43   8e-04
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   43   8e-04
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   43   8e-04
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   43   8e-04
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    43   8e-04
gi|17511435 roundabout homolog 4, magic roundabout [Homo sapiens]      43   8e-04
gi|88702793 slit-like 2 [Homo sapiens]                                 43   8e-04
gi|119392077 Rap guanine nucleotide exchange factor (GEF) 5 [Hom...    42   0.001
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]       42   0.002
gi|237757310 synaptojanin 1 isoform a [Homo sapiens]                   41   0.002
gi|237757308 synaptojanin 1 isoform b [Homo sapiens]                   41   0.002
gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]     40   0.004
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          40   0.004
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          40   0.004
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          40   0.004
gi|46852392 chromobox homolog 6 [Homo sapiens]                         40   0.004
gi|38373682 pleckstrin homology domain containing family G membe...    40   0.005
gi|111154084 pleckstrin homology domain containing family G memb...    40   0.005

>gi|216547801 SH2 domain containing 3C isoform e [Homo sapiens]
          Length = 700

 Score = 1011 bits (2613), Expect = 0.0
 Identities = 506/506 (100%), Positives = 506/506 (100%)

Query: 1   MKRRSVTMTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESP 60
           MKRRSVTMTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESP
Sbjct: 195 MKRRSVTMTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESP 254

Query: 61  SSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHT 120
           SSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHT
Sbjct: 255 SSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHT 314

Query: 121 LGKASPSPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARSYGERLKELSENGAP 180
           LGKASPSPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARSYGERLKELSENGAP
Sbjct: 315 LGKASPSPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARSYGERLKELSENGAP 374

Query: 181 EGDWGKTFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVKELLAEVDARTLARHV 240
           EGDWGKTFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVKELLAEVDARTLARHV
Sbjct: 375 EGDWGKTFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVKELLAEVDARTLARHV 434

Query: 241 TKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGC 300
           TKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGC
Sbjct: 435 TKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGC 494

Query: 301 TGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISRLEQTWVTLRQRHTEG 360
           TGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISRLEQTWVTLRQRHTEG
Sbjct: 495 TGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISRLEQTWVTLRQRHTEG 554

Query: 361 AILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPPEGPEPWGSTEHGVE 420
           AILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPPEGPEPWGSTEHGVE
Sbjct: 555 AILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPPEGPEPWGSTEHGVE 614

Query: 421 VVLAHLEAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSSQA 480
           VVLAHLEAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSSQA
Sbjct: 615 VVLAHLEAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSSQA 674

Query: 481 RRYEKFDKVLTALSHKLEPAVRSSEL 506
           RRYEKFDKVLTALSHKLEPAVRSSEL
Sbjct: 675 RRYEKFDKVLTALSHKLEPAVRSSEL 700


>gi|216547790 SH2 domain containing 3C isoform d [Homo sapiens]
          Length = 702

 Score = 1011 bits (2613), Expect = 0.0
 Identities = 506/506 (100%), Positives = 506/506 (100%)

Query: 1   MKRRSVTMTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESP 60
           MKRRSVTMTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESP
Sbjct: 197 MKRRSVTMTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESP 256

Query: 61  SSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHT 120
           SSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHT
Sbjct: 257 SSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHT 316

Query: 121 LGKASPSPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARSYGERLKELSENGAP 180
           LGKASPSPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARSYGERLKELSENGAP
Sbjct: 317 LGKASPSPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARSYGERLKELSENGAP 376

Query: 181 EGDWGKTFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVKELLAEVDARTLARHV 240
           EGDWGKTFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVKELLAEVDARTLARHV
Sbjct: 377 EGDWGKTFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVKELLAEVDARTLARHV 436

Query: 241 TKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGC 300
           TKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGC
Sbjct: 437 TKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGC 496

Query: 301 TGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISRLEQTWVTLRQRHTEG 360
           TGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISRLEQTWVTLRQRHTEG
Sbjct: 497 TGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISRLEQTWVTLRQRHTEG 556

Query: 361 AILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPPEGPEPWGSTEHGVE 420
           AILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPPEGPEPWGSTEHGVE
Sbjct: 557 AILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPPEGPEPWGSTEHGVE 616

Query: 421 VVLAHLEAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSSQA 480
           VVLAHLEAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSSQA
Sbjct: 617 VVLAHLEAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSSQA 676

Query: 481 RRYEKFDKVLTALSHKLEPAVRSSEL 506
           RRYEKFDKVLTALSHKLEPAVRSSEL
Sbjct: 677 RRYEKFDKVLTALSHKLEPAVRSSEL 702


>gi|216547779 SH2 domain containing 3C isoform c [Homo sapiens]
          Length = 506

 Score = 1011 bits (2613), Expect = 0.0
 Identities = 506/506 (100%), Positives = 506/506 (100%)

Query: 1   MKRRSVTMTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESP 60
           MKRRSVTMTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESP
Sbjct: 1   MKRRSVTMTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESP 60

Query: 61  SSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHT 120
           SSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHT
Sbjct: 61  SSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHT 120

Query: 121 LGKASPSPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARSYGERLKELSENGAP 180
           LGKASPSPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARSYGERLKELSENGAP
Sbjct: 121 LGKASPSPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARSYGERLKELSENGAP 180

Query: 181 EGDWGKTFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVKELLAEVDARTLARHV 240
           EGDWGKTFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVKELLAEVDARTLARHV
Sbjct: 181 EGDWGKTFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVKELLAEVDARTLARHV 240

Query: 241 TKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGC 300
           TKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGC
Sbjct: 241 TKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGC 300

Query: 301 TGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISRLEQTWVTLRQRHTEG 360
           TGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISRLEQTWVTLRQRHTEG
Sbjct: 301 TGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISRLEQTWVTLRQRHTEG 360

Query: 361 AILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPPEGPEPWGSTEHGVE 420
           AILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPPEGPEPWGSTEHGVE
Sbjct: 361 AILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPPEGPEPWGSTEHGVE 420

Query: 421 VVLAHLEAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSSQA 480
           VVLAHLEAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSSQA
Sbjct: 421 VVLAHLEAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSSQA 480

Query: 481 RRYEKFDKVLTALSHKLEPAVRSSEL 506
           RRYEKFDKVLTALSHKLEPAVRSSEL
Sbjct: 481 RRYEKFDKVLTALSHKLEPAVRSSEL 506


>gi|216547769 SH2 domain containing 3C isoform c [Homo sapiens]
          Length = 506

 Score = 1011 bits (2613), Expect = 0.0
 Identities = 506/506 (100%), Positives = 506/506 (100%)

Query: 1   MKRRSVTMTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESP 60
           MKRRSVTMTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESP
Sbjct: 1   MKRRSVTMTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESP 60

Query: 61  SSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHT 120
           SSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHT
Sbjct: 61  SSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHT 120

Query: 121 LGKASPSPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARSYGERLKELSENGAP 180
           LGKASPSPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARSYGERLKELSENGAP
Sbjct: 121 LGKASPSPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARSYGERLKELSENGAP 180

Query: 181 EGDWGKTFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVKELLAEVDARTLARHV 240
           EGDWGKTFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVKELLAEVDARTLARHV
Sbjct: 181 EGDWGKTFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVKELLAEVDARTLARHV 240

Query: 241 TKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGC 300
           TKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGC
Sbjct: 241 TKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGC 300

Query: 301 TGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISRLEQTWVTLRQRHTEG 360
           TGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISRLEQTWVTLRQRHTEG
Sbjct: 301 TGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISRLEQTWVTLRQRHTEG 360

Query: 361 AILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPPEGPEPWGSTEHGVE 420
           AILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPPEGPEPWGSTEHGVE
Sbjct: 361 AILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPPEGPEPWGSTEHGVE 420

Query: 421 VVLAHLEAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSSQA 480
           VVLAHLEAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSSQA
Sbjct: 421 VVLAHLEAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSSQA 480

Query: 481 RRYEKFDKVLTALSHKLEPAVRSSEL 506
           RRYEKFDKVLTALSHKLEPAVRSSEL
Sbjct: 481 RRYEKFDKVLTALSHKLEPAVRSSEL 506


>gi|216547763 SH2 domain containing 3C isoform b [Homo sapiens]
          Length = 703

 Score = 1011 bits (2613), Expect = 0.0
 Identities = 506/506 (100%), Positives = 506/506 (100%)

Query: 1   MKRRSVTMTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESP 60
           MKRRSVTMTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESP
Sbjct: 198 MKRRSVTMTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESP 257

Query: 61  SSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHT 120
           SSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHT
Sbjct: 258 SSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHT 317

Query: 121 LGKASPSPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARSYGERLKELSENGAP 180
           LGKASPSPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARSYGERLKELSENGAP
Sbjct: 318 LGKASPSPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARSYGERLKELSENGAP 377

Query: 181 EGDWGKTFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVKELLAEVDARTLARHV 240
           EGDWGKTFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVKELLAEVDARTLARHV
Sbjct: 378 EGDWGKTFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVKELLAEVDARTLARHV 437

Query: 241 TKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGC 300
           TKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGC
Sbjct: 438 TKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGC 497

Query: 301 TGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISRLEQTWVTLRQRHTEG 360
           TGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISRLEQTWVTLRQRHTEG
Sbjct: 498 TGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISRLEQTWVTLRQRHTEG 557

Query: 361 AILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPPEGPEPWGSTEHGVE 420
           AILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPPEGPEPWGSTEHGVE
Sbjct: 558 AILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPPEGPEPWGSTEHGVE 617

Query: 421 VVLAHLEAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSSQA 480
           VVLAHLEAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSSQA
Sbjct: 618 VVLAHLEAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSSQA 677

Query: 481 RRYEKFDKVLTALSHKLEPAVRSSEL 506
           RRYEKFDKVLTALSHKLEPAVRSSEL
Sbjct: 678 RRYEKFDKVLTALSHKLEPAVRSSEL 703


>gi|41281821 SH2 domain containing 3C isoform a [Homo sapiens]
          Length = 860

 Score = 1011 bits (2613), Expect = 0.0
 Identities = 506/506 (100%), Positives = 506/506 (100%)

Query: 1   MKRRSVTMTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESP 60
           MKRRSVTMTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESP
Sbjct: 355 MKRRSVTMTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESP 414

Query: 61  SSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHT 120
           SSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHT
Sbjct: 415 SSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHT 474

Query: 121 LGKASPSPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARSYGERLKELSENGAP 180
           LGKASPSPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARSYGERLKELSENGAP
Sbjct: 475 LGKASPSPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARSYGERLKELSENGAP 534

Query: 181 EGDWGKTFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVKELLAEVDARTLARHV 240
           EGDWGKTFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVKELLAEVDARTLARHV
Sbjct: 535 EGDWGKTFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVKELLAEVDARTLARHV 594

Query: 241 TKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGC 300
           TKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGC
Sbjct: 595 TKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGC 654

Query: 301 TGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISRLEQTWVTLRQRHTEG 360
           TGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISRLEQTWVTLRQRHTEG
Sbjct: 655 TGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISRLEQTWVTLRQRHTEG 714

Query: 361 AILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPPEGPEPWGSTEHGVE 420
           AILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPPEGPEPWGSTEHGVE
Sbjct: 715 AILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPPEGPEPWGSTEHGVE 774

Query: 421 VVLAHLEAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSSQA 480
           VVLAHLEAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSSQA
Sbjct: 775 VVLAHLEAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSSQA 834

Query: 481 RRYEKFDKVLTALSHKLEPAVRSSEL 506
           RRYEKFDKVLTALSHKLEPAVRSSEL
Sbjct: 835 RRYEKFDKVLTALSHKLEPAVRSSEL 860


>gi|4502371 breast cancer antiestrogen resistance 3 [Homo sapiens]
          Length = 825

 Score =  347 bits (889), Expect = 2e-95
 Identities = 202/468 (43%), Positives = 282/468 (60%), Gaps = 18/468 (3%)

Query: 57  SESPSSPAYSTVTRVHAAPAAPSATALPA-SPVARRSSEPQLCPGSAPKTHGESDKGPHT 115
           S  P+SP + T +    +PA     +  A +  A R S+ QLCP   PK          +
Sbjct: 358 SPCPNSPVFRTGSEPALSPAVVRRVSSDARAGEALRGSDSQLCPKPPPKPCKVPFLKVPS 417

Query: 116 SPSHTLGKASPSPSLSSYSDPDSGHYCQLQPPVRGSRE--WAATETSSQQARSYG----- 168
           SPS  L   +    L+       G   +L    +GS      A +  +   R+ G     
Sbjct: 418 SPSAWLNSEANYCELNPAFATGCGRGAKLPSCAQGSHTELLTAKQNEAPGPRNSGVNYLI 477

Query: 169 ------ERLKELSENGAPEGDWGK-TFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLL 221
                 ER  E +     +G W K  F  P++E  SSF P  F+S  +P +N+PLE  +L
Sbjct: 478 LDDDDRERPWEPAAAQMEKGQWDKGEFVTPLLETVSSFRPNEFESKFLPPENKPLETAML 537

Query: 222 RKVKELLAEVDARTLARHVTKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLD 281
           ++ KEL    D + +A+HV  +DC VARILGV++EM+  MGV  G+EL+TLPHG QLRLD
Sbjct: 538 KRAKELFTNNDPKVIAQHVLSMDCRVARILGVSEEMRRNMGVSSGLELITLPHGHQLRLD 597

Query: 282 LLERFHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMA 341
           ++ER +TM+I +AVDILGCTG+ E+RAA L K IQ+A EL+ +MG+++SF+A+M AL+M 
Sbjct: 598 IIERHNTMAIGIAVDILGCTGTLEDRAATLSKIIQVAVELKDSMGDLYSFSALMKALEMP 657

Query: 342 QISRLEQTWVTLRQRHTEGAILYEKKLKPFLKSLNEGKEGP--PLSNTTFPHVLPLITLL 399
           QI+RLE+TW  LR ++T+ AILYEK+LKPF K L+EG+E    P +N + P ++PL+TL+
Sbjct: 658 QITRLEKTWTALRHQYTQTAILYEKQLKPFSKLLHEGRESTCVPPNNVSVPLLMPLVTLM 717

Query: 400 ECDSAPPEGPEPWGSTEHGVEVVLAHLEAARTVAHHGGLYHTNAEVKLQGFQARPELLEV 459
           E  +   EG + W   +   E++L HL  AR +A     Y  NAE  L GFQ   E+ E+
Sbjct: 718 ERQAVTFEGTDMWEKNDQSCEIMLNHLATARFMAEAADSYRMNAERILAGFQPDEEMNEI 777

Query: 460 FSTEFQMRLLWGSQGASSSQARRYEKFDKVLTALSHKLE-PAVRSSEL 506
             TEFQMRLLWGS+GA  +Q  RYEKF+++LTALS KLE P V+ +EL
Sbjct: 778 CKTEFQMRLLWGSKGAQVNQTERYEKFNQILTALSRKLEPPPVKQAEL 825


>gi|208609985 SH2 domain containing 3A [Homo sapiens]
          Length = 576

 Score =  255 bits (651), Expect = 8e-68
 Identities = 169/455 (37%), Positives = 239/455 (52%), Gaps = 25/455 (5%)

Query: 52  PMSPISESPSSPA-YSTVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESD 110
           P+     S S PA  + + R    PA   A+ +P S + R SS+P L    AP   G   
Sbjct: 138 PLRARKWSNSQPADLAHMGRSREDPAGMEASTMPISALPRTSSDPVLLKAPAPL--GTVA 195

Query: 111 KGPHTSPSHTLGKASPSPSLS-SYSDPDSGH----YCQLQPPVRGSREWAATETSSQQAR 165
                S      KA   P  + S+  PD+      YC+L P V   +  + +++  +   
Sbjct: 196 DSLRASDGQLQAKAPTKPPRTPSFELPDASERPPTYCELVPRVPSVQGTSPSQSCPEPEA 255

Query: 166 SYGERLKELSENGAPEGDWGKTFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVK 225
            + E  ++  E         + FT P  E+  SF P    S L+   NRPLE  +L  ++
Sbjct: 256 PWWEAEEDEEEEN-------RCFTRPQAEI--SFCPHDAPSCLLGPQNRPLEPQVLHTLR 306

Query: 226 ELLAEVDARTLARHVTKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLER 285
            L  E    + A H+  VDC    +LGVT++ +  MGV  G+ELLTLPHG  LRL+LLER
Sbjct: 307 GLFLEHHPGSTALHLLLVDCQATGLLGVTRDQRGNMGVSSGLELLTLPHGHHLRLELLER 366

Query: 286 FHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELR-GTMGNMFSFAAVMGALDMAQIS 344
             T+++  A+ +LGC+G  EERAA L   ++LA  LR G  G++   AAVMGAL M Q+S
Sbjct: 367 HQTLALAGALAVLGCSGPLEERAAALRGLVELALALRPGAAGDLPGLAAVMGALLMPQVS 426

Query: 345 RLEQTWVTLRQRHTEGAILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSA 404
           RLE TW  LR+ HTE A+ +E++LKP +++L+EG           PHV P++ LL     
Sbjct: 427 RLEHTWRQLRRSHTEAALAFEQELKPLMRALDEGAGPCDPGEVALPHVAPMVRLL----- 481

Query: 405 PPEGPEPWGSTEHGVEVVLAHLEAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEF 464
             EG E  G  +   E +L  L  AR +      +   A  +L+GF+  PEL E  +T F
Sbjct: 482 --EGEEVAGPLDESCERLLRTLHGARHMVRDAPKFRKVAAQRLRGFRPNPELREALTTGF 539

Query: 465 QMRLLWGSQGASSSQARRYEKFDKVLTALSHKLEP 499
             RLLWGS+GA + +A R+EKF +VL  LS +LEP
Sbjct: 540 VRRLLWGSRGAGAPRAERFEKFQRVLGVLSQRLEP 574


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 38/131 (29%), Positives = 58/131 (44%), Gaps = 14/131 (10%)

Query: 47   PDLHSPMSPISESPSSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTH 106
            P   SP +P+  +P+ PA +    V  APA+ SA A   +PV    S P   P +  +T 
Sbjct: 1878 PAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPV----SAPNPAPPAPAQTQ 1933

Query: 107  GESDKGPHTSPSHTLGKASPSPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARS 166
             ++ K P  +P  T  ++S  P       P S      Q P     ++ A+  S Q  +S
Sbjct: 1934 AQTHK-PVQNPLQTTSQSSKQP-------PPSIRLPSAQTP--NGTDYVASGKSIQTPQS 1983

Query: 167  YGERLKELSEN 177
            +G    EL +N
Sbjct: 1984 HGTLTAELWDN 1994



 Score = 37.0 bits (84), Expect = 0.042
 Identities = 35/120 (29%), Positives = 52/120 (43%), Gaps = 11/120 (9%)

Query: 20   SDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPA-YSTVTRVHAAPAAP 78
            S   P   S P P  +  S   S      L + ++P+  S S+P   ST+  V A+ +AP
Sbjct: 1743 SASVPPLASAPLPPSTSASVPASTSA--PLPATLTPVPASTSAPVPASTLAPVLASTSAP 1800

Query: 79   SATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHTLGKASPSPSLSSYSDPDS 138
               A P +PV+  +S     P S       S   P ++P       +P+P L+S S P S
Sbjct: 1801 -VPASPLAPVSASASVSASVPASTSAAAITSSSAPASAP-------APTPILASVSTPAS 1852



 Score = 33.1 bits (74), Expect = 0.61
 Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 9/87 (10%)

Query: 24   PTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISES-------PSSPAYSTVTRVHAAPA 76
            P STS P P  ++    L+    P   SP++P+S S       P+S + + +T   A  +
Sbjct: 1778 PASTSAPVPASTLAP-VLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPAS 1836

Query: 77   APSATALPASPVARRSSEPQLCPGSAP 103
            AP+ T + AS V+  +S   L   S P
Sbjct: 1837 APAPTPILAS-VSTPASVTILASASIP 1862


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 43/123 (34%), Positives = 57/123 (46%), Gaps = 7/123 (5%)

Query: 24   PTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYSTVTRVHAAPAAPSATAL 83
            PTS S      S    + S       +SP SP S SP+SP+YS  +  ++ P +PS +  
Sbjct: 1638 PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP-SYSPTSPSYSPTSPSYS-PTSPSYS-- 1693

Query: 84   PASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHTLGKASPSPSLSSYSDPDSGHYCQ 143
            P SP    +S P   P S P     S     TSPS++    S SP+  SYS P S +Y  
Sbjct: 1694 PTSPSYSPTS-PSYSPTS-PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS-PTSPNYSP 1750

Query: 144  LQP 146
              P
Sbjct: 1751 TSP 1753



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 39/126 (30%), Positives = 54/126 (42%), Gaps = 6/126 (4%)

Query: 24   PTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYSTVTRVHAAPAAPSATAL 83
            PTS S      S    + +       +SP SP S SP+SP+YS  +  ++ P +PS +  
Sbjct: 1617 PTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSP-SYSPTSPSYSPTSPSYS-PTSPSYSPT 1674

Query: 84   PASPVARRSSEPQLCPGSAPKTHGESDKGPH---TSPSHTLGKASPSPSLSSYSDPDSGH 140
              S      S     P  +P +   S   P    TSPS++    S SP+  SYS P S  
Sbjct: 1675 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS-PTSPS 1733

Query: 141  YCQLQP 146
            Y    P
Sbjct: 1734 YSPTSP 1739



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 35/100 (35%), Positives = 47/100 (47%), Gaps = 6/100 (6%)

Query: 50   HSPMSPISESPSSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGES 109
            +SP SP S SP+SP+YS  T  + +P +PS +    S      S     P  +P +   S
Sbjct: 1615 YSPTSP-SYSPTSPSYSP-TSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1672

Query: 110  DKGPH---TSPSHTLGKASPSPSLSSYSDPDSGHYCQLQP 146
               P    TSPS++    S SP+  SYS P S  Y    P
Sbjct: 1673 PTSPSYSPTSPSYSPTSPSYSPTSPSYS-PTSPSYSPTSP 1711



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 41/123 (33%), Positives = 56/123 (45%), Gaps = 7/123 (5%)

Query: 24   PTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYSTVTRVHAAPAAPSATAL 83
            PTS S      S    + S       ++P SP + +PSSP+YS  +  ++ P +P  T  
Sbjct: 1785 PTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSP-TYTPSSPSYSPSSPSYS-PTSPKYT-- 1840

Query: 84   PASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHTLGKASPSPSLSSYSDPDSGHYCQ 143
            P SP    SS P+  P S PK    S K   TSP ++    + SP+   YS P S  Y  
Sbjct: 1841 PTSPSYSPSS-PEYTPTS-PKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYS-PTSPTYSP 1897

Query: 144  LQP 146
              P
Sbjct: 1898 TSP 1900



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 41/123 (33%), Positives = 55/123 (44%), Gaps = 7/123 (5%)

Query: 24   PTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYSTVTRVHAAPAAPSATAL 83
            PTS S      S    + +       ++P SP S SP+SP+YS  T  +  P +P+ +  
Sbjct: 1729 PTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSP-SYSPTSPSYSP-TSPNYTPTSPNYS-- 1784

Query: 84   PASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHTLGKASPSPSLSSYSDPDSGHYCQ 143
            P SP    +S P   P S P     S +    SP++T    S SPS  SYS P S  Y  
Sbjct: 1785 PTSPSYSPTS-PSYSPTS-PSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYS-PTSPKYTP 1841

Query: 144  LQP 146
              P
Sbjct: 1842 TSP 1844



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 35/126 (27%), Positives = 53/126 (42%), Gaps = 8/126 (6%)

Query: 24   PTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYSTVTRVHAAPAAPSATAL 83
            P+S  +P P  ++     S       + P SP   +P SP+YS  +  ++ P +PS +  
Sbjct: 1577 PSSPYIPSPGGAMSP---SYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYS-PTSPSYSPT 1632

Query: 84   PASPVARRSSEPQLCPGSAPKTHGESDKGPH---TSPSHTLGKASPSPSLSSYSDPDSGH 140
              +      S     P  +P +   S   P    TSPS++    S SP+  SYS P S  
Sbjct: 1633 SPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS-PTSPS 1691

Query: 141  YCQLQP 146
            Y    P
Sbjct: 1692 YSPTSP 1697



 Score = 38.5 bits (88), Expect = 0.015
 Identities = 40/123 (32%), Positives = 54/123 (43%), Gaps = 14/123 (11%)

Query: 24   PTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYSTVTRVHAAPAAPSATAL 83
            PTS S      S    + +       +SP SP S SP+SP+YS  +  ++ P++P  T  
Sbjct: 1757 PTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSP-SYSPTSPSYSPTSPSYS-PSSPRYT-- 1812

Query: 84   PASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHTLGKASPSPSLSSYSDPDSGHYCQ 143
            P SP    SS     P  +P +   S     TSP +T    S SPS   Y+ P S  Y  
Sbjct: 1813 PQSPTYTPSS-----PSYSPSSPSYSP----TSPKYTPTSPSYSPSSPEYT-PTSPKYSP 1862

Query: 144  LQP 146
              P
Sbjct: 1863 TSP 1865


>gi|148747862 Rap guanine nucleotide exchange factor 3 isoform b
           [Homo sapiens]
          Length = 881

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 56/192 (29%), Positives = 86/192 (44%), Gaps = 14/192 (7%)

Query: 208 LIPRDNRPLEVGLLRKVKELLAEVDARTLARHVTKVDCLVARILGVTKEMQTLMGVRWGM 267
           LIP    P ++G      E L  V A+ LA  +T  D  +   +   + +  ++G +   
Sbjct: 599 LIPH---PDQLGPTVGSAEGLDLVSAKDLAGQLTDHDWSLFNSIHQVELIHYVLGPQHLR 655

Query: 268 ELLTLPHGRQLRLDLLERFHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRGTMGN 327
           ++ T    R +R     RF+ +   +A ++  C      RA LL K I+LAA L+    N
Sbjct: 656 DVTTANLERFMR-----RFNELQYWVATELCLCPVPGP-RAQLLRKFIKLAAHLK-EQKN 708

Query: 328 MFSFAAVMGALDMAQISRLEQTWVTLRQRHTEGAILYEKKLKPFLKSLNEGKEGPPLSNT 387
           + SF AVM  L  + ISRL  TW  L  +  +     E+ L P   S N       L+  
Sbjct: 709 LNSFFAVMFGLSNSAISRLAHTWERLPHKVRKLYSALERLLDP---SWNHRVYRLALAKL 765

Query: 388 TFPHVLPLITLL 399
           + P V+P + LL
Sbjct: 766 S-PPVIPFMPLL 776


>gi|20070215 Rap guanine nucleotide exchange factor 3 isoform b
           [Homo sapiens]
          Length = 881

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 56/192 (29%), Positives = 86/192 (44%), Gaps = 14/192 (7%)

Query: 208 LIPRDNRPLEVGLLRKVKELLAEVDARTLARHVTKVDCLVARILGVTKEMQTLMGVRWGM 267
           LIP    P ++G      E L  V A+ LA  +T  D  +   +   + +  ++G +   
Sbjct: 599 LIPH---PDQLGPTVGSAEGLDLVSAKDLAGQLTDHDWSLFNSIHQVELIHYVLGPQHLR 655

Query: 268 ELLTLPHGRQLRLDLLERFHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRGTMGN 327
           ++ T    R +R     RF+ +   +A ++  C      RA LL K I+LAA L+    N
Sbjct: 656 DVTTANLERFMR-----RFNELQYWVATELCLCPVPGP-RAQLLRKFIKLAAHLK-EQKN 708

Query: 328 MFSFAAVMGALDMAQISRLEQTWVTLRQRHTEGAILYEKKLKPFLKSLNEGKEGPPLSNT 387
           + SF AVM  L  + ISRL  TW  L  +  +     E+ L P   S N       L+  
Sbjct: 709 LNSFFAVMFGLSNSAISRLAHTWERLPHKVRKLYSALERLLDP---SWNHRVYRLALAKL 765

Query: 388 TFPHVLPLITLL 399
           + P V+P + LL
Sbjct: 766 S-PPVIPFMPLL 776


>gi|148747859 Rap guanine nucleotide exchange factor 3 isoform a
           [Homo sapiens]
          Length = 923

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 56/192 (29%), Positives = 86/192 (44%), Gaps = 14/192 (7%)

Query: 208 LIPRDNRPLEVGLLRKVKELLAEVDARTLARHVTKVDCLVARILGVTKEMQTLMGVRWGM 267
           LIP    P ++G      E L  V A+ LA  +T  D  +   +   + +  ++G +   
Sbjct: 641 LIPH---PDQLGPTVGSAEGLDLVSAKDLAGQLTDHDWSLFNSIHQVELIHYVLGPQHLR 697

Query: 268 ELLTLPHGRQLRLDLLERFHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRGTMGN 327
           ++ T    R +R     RF+ +   +A ++  C      RA LL K I+LAA L+    N
Sbjct: 698 DVTTANLERFMR-----RFNELQYWVATELCLCPVPGP-RAQLLRKFIKLAAHLK-EQKN 750

Query: 328 MFSFAAVMGALDMAQISRLEQTWVTLRQRHTEGAILYEKKLKPFLKSLNEGKEGPPLSNT 387
           + SF AVM  L  + ISRL  TW  L  +  +     E+ L P   S N       L+  
Sbjct: 751 LNSFFAVMFGLSNSAISRLAHTWERLPHKVRKLYSALERLLDP---SWNHRVYRLALAKL 807

Query: 388 TFPHVLPLITLL 399
           + P V+P + LL
Sbjct: 808 S-PPVIPFMPLL 818


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 31/138 (22%), Positives = 52/138 (37%), Gaps = 10/138 (7%)

Query: 2   KRRSVTMTDGLTADKVTRSDGCPTSTSLPRP----RDSIRSCALSMDQIPDLHSPMSPIS 57
           K ++ +  +  + +K +  D  PTS  L +P      + +  AL+  + P   +P  P S
Sbjct: 167 KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAS 226

Query: 58  ESPSSPAYSTVTRVHAAPAAP------SATALPASPVARRSSEPQLCPGSAPKTHGESDK 111
            +P  P  +T+      P  P      SA   P  P    + EP       P      + 
Sbjct: 227 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEP 286

Query: 112 GPHTSPSHTLGKASPSPS 129
            P T+ S       P+P+
Sbjct: 287 APTTTKSAPTTPKEPAPT 304



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 29/119 (24%), Positives = 41/119 (34%), Gaps = 8/119 (6%)

Query: 18  TRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYST-----VTRVH 72
           T +   PT+   P P    +  A +  + P   +P  P   +P  PA +T      T   
Sbjct: 289 TTTKSAPTTPKEPAPTTP-KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE 347

Query: 73  AAPAAPS--ATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHTLGKASPSPS 129
            AP AP   A   P  P      EP       P      +  P T+ S       P+P+
Sbjct: 348 PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 406



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 30/113 (26%), Positives = 44/113 (38%), Gaps = 9/113 (7%)

Query: 24  PTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYSTVTRVHAAPAAPSATAL 83
           PT T+   P  + +  A +  + P   +P  P   +P  PA +T         AP+ T  
Sbjct: 325 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT-----PKEPAPTTTKE 379

Query: 84  PASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHTLGKASPSPSLSSYSDP 136
           P SP   +   P     SAP T    +  P T+ S       PSP+ +    P
Sbjct: 380 P-SPTTPKEPAPTTTK-SAPTT--TKEPAPTTTKSAPTTPKEPSPTTTKEPAP 428


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 31/138 (22%), Positives = 52/138 (37%), Gaps = 10/138 (7%)

Query: 2   KRRSVTMTDGLTADKVTRSDGCPTSTSLPRP----RDSIRSCALSMDQIPDLHSPMSPIS 57
           K ++ +  +  + +K +  D  PTS  L +P      + +  AL+  + P   +P  P S
Sbjct: 208 KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAS 267

Query: 58  ESPSSPAYSTVTRVHAAPAAP------SATALPASPVARRSSEPQLCPGSAPKTHGESDK 111
            +P  P  +T+      P  P      SA   P  P    + EP       P      + 
Sbjct: 268 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEP 327

Query: 112 GPHTSPSHTLGKASPSPS 129
            P T+ S       P+P+
Sbjct: 328 APTTTKSAPTTPKEPAPT 345



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 29/119 (24%), Positives = 41/119 (34%), Gaps = 8/119 (6%)

Query: 18  TRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYST-----VTRVH 72
           T +   PT+   P P    +  A +  + P   +P  P   +P  PA +T      T   
Sbjct: 330 TTTKSAPTTPKEPAPTTP-KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE 388

Query: 73  AAPAAPS--ATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHTLGKASPSPS 129
            AP AP   A   P  P      EP       P      +  P T+ S       P+P+
Sbjct: 389 PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 447



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 30/113 (26%), Positives = 44/113 (38%), Gaps = 9/113 (7%)

Query: 24  PTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYSTVTRVHAAPAAPSATAL 83
           PT T+   P  + +  A +  + P   +P  P   +P  PA +T         AP+ T  
Sbjct: 366 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT-----PKEPAPTTTKE 420

Query: 84  PASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHTLGKASPSPSLSSYSDP 136
           P SP   +   P     SAP T    +  P T+ S       PSP+ +    P
Sbjct: 421 P-SPTTPKEPAPTTTK-SAPTT--TKEPAPTTTKSAPTTPKEPSPTTTKEPAP 469


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 31/138 (22%), Positives = 52/138 (37%), Gaps = 10/138 (7%)

Query: 2   KRRSVTMTDGLTADKVTRSDGCPTSTSLPRP----RDSIRSCALSMDQIPDLHSPMSPIS 57
           K ++ +  +  + +K +  D  PTS  L +P      + +  AL+  + P   +P  P S
Sbjct: 260 KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAS 319

Query: 58  ESPSSPAYSTVTRVHAAPAAP------SATALPASPVARRSSEPQLCPGSAPKTHGESDK 111
            +P  P  +T+      P  P      SA   P  P    + EP       P      + 
Sbjct: 320 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEP 379

Query: 112 GPHTSPSHTLGKASPSPS 129
            P T+ S       P+P+
Sbjct: 380 APTTTKSAPTTPKEPAPT 397



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 29/119 (24%), Positives = 41/119 (34%), Gaps = 8/119 (6%)

Query: 18  TRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYST-----VTRVH 72
           T +   PT+   P P    +  A +  + P   +P  P   +P  PA +T      T   
Sbjct: 382 TTTKSAPTTPKEPAPTTP-KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE 440

Query: 73  AAPAAPS--ATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHTLGKASPSPS 129
            AP AP   A   P  P      EP       P      +  P T+ S       P+P+
Sbjct: 441 PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 499



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 30/113 (26%), Positives = 44/113 (38%), Gaps = 9/113 (7%)

Query: 24  PTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYSTVTRVHAAPAAPSATAL 83
           PT T+   P  + +  A +  + P   +P  P   +P  PA +T         AP+ T  
Sbjct: 418 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT-----PKEPAPTTTKE 472

Query: 84  PASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHTLGKASPSPSLSSYSDP 136
           P SP   +   P     SAP T    +  P T+ S       PSP+ +    P
Sbjct: 473 P-SPTTPKEPAPTTTK-SAPTT--TKEPAPTTTKSAPTTPKEPSPTTTKEPAP 521


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 31/138 (22%), Positives = 52/138 (37%), Gaps = 10/138 (7%)

Query: 2   KRRSVTMTDGLTADKVTRSDGCPTSTSLPRP----RDSIRSCALSMDQIPDLHSPMSPIS 57
           K ++ +  +  + +K +  D  PTS  L +P      + +  AL+  + P   +P  P S
Sbjct: 301 KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAS 360

Query: 58  ESPSSPAYSTVTRVHAAPAAP------SATALPASPVARRSSEPQLCPGSAPKTHGESDK 111
            +P  P  +T+      P  P      SA   P  P    + EP       P      + 
Sbjct: 361 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEP 420

Query: 112 GPHTSPSHTLGKASPSPS 129
            P T+ S       P+P+
Sbjct: 421 APTTTKSAPTTPKEPAPT 438



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 29/119 (24%), Positives = 41/119 (34%), Gaps = 8/119 (6%)

Query: 18  TRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYST-----VTRVH 72
           T +   PT+   P P    +  A +  + P   +P  P   +P  PA +T      T   
Sbjct: 423 TTTKSAPTTPKEPAPTTP-KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE 481

Query: 73  AAPAAPS--ATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHTLGKASPSPS 129
            AP AP   A   P  P      EP       P      +  P T+ S       P+P+
Sbjct: 482 PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 540



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 30/113 (26%), Positives = 44/113 (38%), Gaps = 9/113 (7%)

Query: 24  PTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYSTVTRVHAAPAAPSATAL 83
           PT T+   P  + +  A +  + P   +P  P   +P  PA +T         AP+ T  
Sbjct: 459 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT-----PKEPAPTTTKE 513

Query: 84  PASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHTLGKASPSPSLSSYSDP 136
           P SP   +   P     SAP T    +  P T+ S       PSP+ +    P
Sbjct: 514 P-SPTTPKEPAPTTTK-SAPTT--TKEPAPTTTKSAPTTPKEPSPTTTKEPAP 562


>gi|17511435 roundabout homolog 4, magic roundabout [Homo sapiens]
          Length = 1007

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 8/94 (8%)

Query: 42  SMDQIPDLHSPMSPISESPSSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCPGS 101
           S +++   H P +P+    + P  S  T+   AP APS+  LPA+P+      P L P S
Sbjct: 705 SSNELVTRHLPPAPLFPHETPPTQSQQTQPPVAPQAPSSILLPAAPI------PILSPCS 758

Query: 102 APKTHGESDKGPHTSPSHTLGKASPSPSLSSYSD 135
            P     S  GP  SP+ +   +S   SL    D
Sbjct: 759 PPSPQASSLSGP--SPASSRLSSSSLSSLGEDQD 790


>gi|88702793 slit-like 2 [Homo sapiens]
          Length = 673

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 41/125 (32%), Positives = 52/125 (41%), Gaps = 8/125 (6%)

Query: 22  GCPTSTS---LPRPRDSIRS-CALSMDQIPDLHSPMSPISESPSSP--AYSTVTRVHAAP 75
           GCP +T+   +P  R  +R   ALS    P   SP  P +E+PS P  A  TV  V    
Sbjct: 348 GCPATTTTATVPTTRPVVREPTALSSSLAPTWLSPTEPATEAPSPPSTAPPTVGPVPQPQ 407

Query: 76  AAPSATALPASP--VARRSSEPQLCPGSAPKTHGESDKGPHTSPSHTLGKASPSPSLSSY 133
             P +T L      +  R     LCP      + ES  G  T PS T     P  SL+  
Sbjct: 408 DCPPSTCLNGGTCHLGTRHHLACLCPEGFTGLYCESQMGQGTRPSPTPVTPRPPRSLTLG 467

Query: 134 SDPDS 138
            +P S
Sbjct: 468 IEPVS 472


>gi|119392077 Rap guanine nucleotide exchange factor (GEF) 5 [Homo
           sapiens]
          Length = 730

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 25/69 (36%), Positives = 42/69 (60%), Gaps = 2/69 (2%)

Query: 282 LLERFHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMA 341
           LL+R + + + +A +IL C+    +R  L+ K I++AA  +    N+ SF A++  L+ A
Sbjct: 539 LLQRCNEVQLWVATEILLCS-QLGKRVQLVKKFIKIAAHCKAQR-NLNSFFAIVMGLNTA 596

Query: 342 QISRLEQTW 350
            +SRL QTW
Sbjct: 597 SVSRLSQTW 605


>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
          Length = 788

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 43/145 (29%), Positives = 63/145 (43%), Gaps = 20/145 (13%)

Query: 40  ALSMDQIPDLHSPMSPISESPSSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCP 99
           A+    IP    PM+ +S+S S P  S+      +P     T     P  + S +P   P
Sbjct: 409 AIPSSSIPLGRQPMAQVSQS-SLPMLSS-----PSPGQQVQTPQSMPPPPQPSPQPGQ-P 461

Query: 100 GSAPKTHGESDKGPHTSPSHTLGKASPSPSLS--------SYSDPDSGHYCQLQPPVRGS 151
            S P ++  S  GP  SPS  L   SP PS S        ++S P  G    L  PV  S
Sbjct: 462 SSQPNSNVSS--GPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPG---PLNTPVNPS 516

Query: 152 REWAATETSSQQARSYGERLKELSE 176
              +   +S  + + Y ++LK+LS+
Sbjct: 517 SVMSPAGSSQAEEQQYLDKLKQLSK 541


>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
          Length = 1612

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 53/222 (23%), Positives = 79/222 (35%), Gaps = 25/222 (11%)

Query: 4    RSVTMTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIP--DLHSPMSPISESPS 61
            +S T+++G       R    P+ T  P    S    A     +P  D   P+ P    P 
Sbjct: 1091 QSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPP 1150

Query: 62   SPAYSTVTRVHAAPAAPSATALPASPVARRSSEP---QLCPGSAPKTHG------ESDKG 112
             P         A P  P+    P  P   RS  P   +     AP + G      E+ K 
Sbjct: 1151 RPV--------APPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAPKS 1202

Query: 113  PHTSPSHTLGKASPSPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARSYGERLK 172
            P T+    +G++ PSP  +  + P    Y   +P +               AR+   RL 
Sbjct: 1203 PGTTRKDNIGRSQPSPQ-AGLAGPGPAGYSTARPTI--PPRAGVISAPQSHARASAGRLT 1259

Query: 173  ELSENGAPEGDWGKTFTVPIVEVTSSFNPATFQSLLIPRDNR 214
              S++   E   G TF    ++  ++F P   QS L P   R
Sbjct: 1260 PESQSKTSETSKGSTFLPEPLKPQAAFPP---QSSLPPPAQR 1298


>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
          Length = 1350

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 53/222 (23%), Positives = 79/222 (35%), Gaps = 25/222 (11%)

Query: 4    RSVTMTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIP--DLHSPMSPISESPS 61
            +S T+++G       R    P+ T  P    S    A     +P  D   P+ P    P 
Sbjct: 1091 QSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPP 1150

Query: 62   SPAYSTVTRVHAAPAAPSATALPASPVARRSSEP---QLCPGSAPKTHG------ESDKG 112
             P         A P  P+    P  P   RS  P   +     AP + G      E+ K 
Sbjct: 1151 RPV--------APPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAPKS 1202

Query: 113  PHTSPSHTLGKASPSPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARSYGERLK 172
            P T+    +G++ PSP  +  + P    Y   +P +               AR+   RL 
Sbjct: 1203 PGTTRKDNIGRSQPSPQ-AGLAGPGPAGYSTARPTI--PPRAGVISAPQSHARASAGRLT 1259

Query: 173  ELSENGAPEGDWGKTFTVPIVEVTSSFNPATFQSLLIPRDNR 214
              S++   E   G TF    ++  ++F P   QS L P   R
Sbjct: 1260 PESQSKTSETSKGSTFLPEPLKPQAAFPP---QSSLPPPAQR 1298


>gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]
          Length = 2013

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 27/111 (24%), Positives = 49/111 (44%), Gaps = 3/111 (2%)

Query: 9    TDGLTADKVTRSDGCPTS-TSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYST 67
            T   T+    R+   PT+ T+   P  +      +   +P   +  +P +   S+P  ST
Sbjct: 1900 TTSTTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTST 1959

Query: 68   VTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPS 118
             +   ++  +   T+  ++P +  +S PQ    SAP T   +  GP T+PS
Sbjct: 1960 TSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTT--STTSGPGTTPS 2008


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 41/156 (26%), Positives = 58/156 (37%), Gaps = 18/156 (11%)

Query: 10  DGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQI------PDLHSPM----SPISES 59
           +G +  K    D   TS S+P P+D+      S  Q       P L +P     +P S  
Sbjct: 142 EGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP 201

Query: 60  PSSPAYSTVTRVHAAPA-----APSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPH 114
           P +P   T     +A A     +P+A+  P  P A  +  P      AP  H +    PH
Sbjct: 202 PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH 261

Query: 115 TSPSHTLGKASPSPSLSSYSDPDSGHYCQLQPPVRG 150
             P H        P   S   P +  +   QPP+ G
Sbjct: 262 -PPPHPSPHPPLQPLTGSAGQPSAPSHA--QPPLHG 294



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 22/92 (23%), Positives = 38/92 (41%), Gaps = 3/92 (3%)

Query: 24  PTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYSTVTRVHAAPAAPSATAL 83
           P++T++P       S A +  Q P    P + I ++P+       +     P  PS    
Sbjct: 214 PSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSP--HPPPHPSPHP- 270

Query: 84  PASPVARRSSEPQLCPGSAPKTHGESDKGPHT 115
           P  P+   + +P     + P  HG+   GPH+
Sbjct: 271 PLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHS 302


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 41/156 (26%), Positives = 58/156 (37%), Gaps = 18/156 (11%)

Query: 10  DGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQI------PDLHSPM----SPISES 59
           +G +  K    D   TS S+P P+D+      S  Q       P L +P     +P S  
Sbjct: 696 EGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP 755

Query: 60  PSSPAYSTVTRVHAAPA-----APSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPH 114
           P +P   T     +A A     +P+A+  P  P A  +  P      AP  H +    PH
Sbjct: 756 PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH 815

Query: 115 TSPSHTLGKASPSPSLSSYSDPDSGHYCQLQPPVRG 150
             P H        P   S   P +  +   QPP+ G
Sbjct: 816 -PPPHPSPHPPLQPLTGSAGQPSAPSHA--QPPLHG 848



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 22/92 (23%), Positives = 38/92 (41%), Gaps = 3/92 (3%)

Query: 24  PTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYSTVTRVHAAPAAPSATAL 83
           P++T++P       S A +  Q P    P + I ++P+       +     P  PS    
Sbjct: 768 PSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSP--HPPPHPSPHP- 824

Query: 84  PASPVARRSSEPQLCPGSAPKTHGESDKGPHT 115
           P  P+   + +P     + P  HG+   GPH+
Sbjct: 825 PLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHS 856


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 41/156 (26%), Positives = 58/156 (37%), Gaps = 18/156 (11%)

Query: 10  DGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQI------PDLHSPM----SPISES 59
           +G +  K    D   TS S+P P+D+      S  Q       P L +P     +P S  
Sbjct: 696 EGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP 755

Query: 60  PSSPAYSTVTRVHAAPA-----APSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPH 114
           P +P   T     +A A     +P+A+  P  P A  +  P      AP  H +    PH
Sbjct: 756 PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH 815

Query: 115 TSPSHTLGKASPSPSLSSYSDPDSGHYCQLQPPVRG 150
             P H        P   S   P +  +   QPP+ G
Sbjct: 816 -PPPHPSPHPPLQPLTGSAGQPSAPSHA--QPPLHG 848



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 22/92 (23%), Positives = 38/92 (41%), Gaps = 3/92 (3%)

Query: 24  PTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYSTVTRVHAAPAAPSATAL 83
           P++T++P       S A +  Q P    P + I ++P+       +     P  PS    
Sbjct: 768 PSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSP--HPPPHPSPHP- 824

Query: 84  PASPVARRSSEPQLCPGSAPKTHGESDKGPHT 115
           P  P+   + +P     + P  HG+   GPH+
Sbjct: 825 PLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHS 856


>gi|46852392 chromobox homolog 6 [Homo sapiens]
          Length = 412

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 41/157 (26%), Positives = 62/157 (39%), Gaps = 20/157 (12%)

Query: 73  AAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHTLGKASPS---PS 129
           +AP      A PA+P   RSS    CP   P++    D  P   P  T+  ++PS   P 
Sbjct: 253 SAPGPGLLLAAPAAPYDARSSGSSGCPSPTPQSSDPDDTPPKLLP-ETVSPSAPSWREPE 311

Query: 130 LSSYS-DPDSGHYCQLQPPVRGSREWAATETSSQQARSYGERLKELSENGAPE-GDWGKT 187
           +   S  P+S    +  PP   +    A  T+ + A +  E          PE GDW   
Sbjct: 312 VLDLSLPPESAATSKRAPPEVTAAAGPAPPTAPEPAGASSE----------PEAGDWRPE 361

Query: 188 FT----VPIVEVTSSFNPATFQSLLIPRDNRPLEVGL 220
            +    V + +VTS+    T +    P D   +  G+
Sbjct: 362 MSPCSNVVVTDVTSNLLTVTIKEFCNPEDFEKVAAGV 398


>gi|38373682 pleckstrin homology domain containing family G member 5
           isoform a [Homo sapiens]
          Length = 1006

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 51/185 (27%), Positives = 73/185 (39%), Gaps = 22/185 (11%)

Query: 13  TADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYSTVTRVH 72
           T+   T S   PTS  LP      RSC  SMD      SP S        P    V R  
Sbjct: 787 TSLSTTASSATPTSELLPLGPVDGRSC--SMDSAYGTLSPTSLQDFVAPGPMAELVPR-- 842

Query: 73  AAPAAPSATALPASPVARRSSEPQL--CPGSAPKTHGESD----------KGPHTSPSHT 120
            AP +P   + P SP  RR +  QL  CP    K+  E+            G  ++PS +
Sbjct: 843 -APESPRVPSPPPSPRLRRRTPVQLLSCPPHLLKSKSEASLLQLLAGAGTHGTPSAPSRS 901

Query: 121 LGK---ASPSPSLSSYSDP-DSGHYCQLQ-PPVRGSREWAATETSSQQARSYGERLKELS 175
           L +   A P+P + +   P ++G     +  P  GS        + + A S+ +R  +L 
Sbjct: 902 LSELCLAVPAPGIRTQGSPQEAGPSWDCRGAPSPGSGPGLVGCLAGEPAGSHRKRCGDLP 961

Query: 176 ENGAP 180
              +P
Sbjct: 962 SGASP 966


>gi|111154084 pleckstrin homology domain containing family G member 5
            isoform b [Homo sapiens]
          Length = 1083

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 51/185 (27%), Positives = 73/185 (39%), Gaps = 22/185 (11%)

Query: 13   TADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYSTVTRVH 72
            T+   T S   PTS  LP      RSC  SMD      SP S        P    V R  
Sbjct: 864  TSLSTTASSATPTSELLPLGPVDGRSC--SMDSAYGTLSPTSLQDFVAPGPMAELVPR-- 919

Query: 73   AAPAAPSATALPASPVARRSSEPQL--CPGSAPKTHGESD----------KGPHTSPSHT 120
             AP +P   + P SP  RR +  QL  CP    K+  E+            G  ++PS +
Sbjct: 920  -APESPRVPSPPPSPRLRRRTPVQLLSCPPHLLKSKSEASLLQLLAGAGTHGTPSAPSRS 978

Query: 121  LGK---ASPSPSLSSYSDP-DSGHYCQLQ-PPVRGSREWAATETSSQQARSYGERLKELS 175
            L +   A P+P + +   P ++G     +  P  GS        + + A S+ +R  +L 
Sbjct: 979  LSELCLAVPAPGIRTQGSPQEAGPSWDCRGAPSPGSGPGLVGCLAGEPAGSHRKRCGDLP 1038

Query: 176  ENGAP 180
               +P
Sbjct: 1039 SGASP 1043


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.129    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,858,643
Number of Sequences: 37866
Number of extensions: 1090302
Number of successful extensions: 6741
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 67
Number of HSP's successfully gapped in prelim test: 392
Number of HSP's that attempted gapping in prelim test: 5664
Number of HSP's gapped (non-prelim): 1233
length of query: 506
length of database: 18,247,518
effective HSP length: 107
effective length of query: 399
effective length of database: 14,195,856
effective search space: 5664146544
effective search space used: 5664146544
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.