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Search of human proteins with 21553317
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21553317 SFT2 domain containing 1 [Homo sapiens]
(159 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21553317 SFT2 domain containing 1 [Homo sapiens] 324 2e-89
gi|40786408 SFT2 domain containing 2 [Homo sapiens] 213 6e-56
gi|33413418 signal peptide peptidase 3 [Homo sapiens] 33 0.079
gi|13994190 frizzled 8 [Homo sapiens] 32 0.18
gi|27894385 frizzled 5 precursor [Homo sapiens] 31 0.39
gi|31542731 major facilitator superfamily domain containing 7 [H... 31 0.39
gi|30039714 otopetrin 2 [Homo sapiens] 28 3.3
gi|225637544 olfactory receptor, family 56, subfamily A, member ... 28 4.3
gi|169202671 PREDICTED: olfactory receptor, family 56, subfamily... 28 4.3
gi|89034551 PREDICTED: olfactory receptor, family 56, subfamily ... 28 4.3
gi|239744276 PREDICTED: olfactory receptor, family 56, subfamily... 28 4.3
gi|62526033 ATP-binding cassette, sub-family G, member 2 [Homo s... 27 5.6
gi|31317278 WD repeat domain 20 isoform 3 [Homo sapiens] 27 5.6
gi|31317276 WD repeat domain 20 isoform 4 [Homo sapiens] 27 5.6
gi|31317274 WD repeat domain 20 isoform 1 [Homo sapiens] 27 5.6
gi|31317280 WD repeat domain 20 isoform 2 [Homo sapiens] 27 5.6
gi|53933287 olfactory receptor, family 5, subfamily K, member 4 ... 27 5.6
gi|5454070 solute carrier family 9 (sodium/hydrogen exchanger), ... 27 7.4
gi|110227626 solute carrier family 9 (sodium/hydrogen exchanger)... 27 7.4
gi|115270955 olfactory receptor, family 5, subfamily K, member 1... 27 7.4
gi|47679099 Kazal type serine protease inhibitor 5-like 2 [Homo ... 27 7.4
gi|53933278 olfactory receptor, family 5, subfamily K, member 3 ... 27 9.6
>gi|21553317 SFT2 domain containing 1 [Homo sapiens]
Length = 159
Score = 324 bits (831), Expect = 2e-89
Identities = 159/159 (100%), Positives = 159/159 (100%)
Query: 1 MEKLRRVLSGQDDEEQGLTAQVLDASSLSFNTRLKWFAICFVCGVFFSILGTGLLWLPGG 60
MEKLRRVLSGQDDEEQGLTAQVLDASSLSFNTRLKWFAICFVCGVFFSILGTGLLWLPGG
Sbjct: 1 MEKLRRVLSGQDDEEQGLTAQVLDASSLSFNTRLKWFAICFVCGVFFSILGTGLLWLPGG 60
Query: 61 IKLFAVFYTLGNLAALASTCFLMGPVKQLKKMFEATRLLATIVMLLCFIFTLCAALWWHK 120
IKLFAVFYTLGNLAALASTCFLMGPVKQLKKMFEATRLLATIVMLLCFIFTLCAALWWHK
Sbjct: 61 IKLFAVFYTLGNLAALASTCFLMGPVKQLKKMFEATRLLATIVMLLCFIFTLCAALWWHK 120
Query: 121 KGLAVLFCILQFLSMTWYSLSYIPYARDAVIKCCSSLLS 159
KGLAVLFCILQFLSMTWYSLSYIPYARDAVIKCCSSLLS
Sbjct: 121 KGLAVLFCILQFLSMTWYSLSYIPYARDAVIKCCSSLLS 159
>gi|40786408 SFT2 domain containing 2 [Homo sapiens]
Length = 160
Score = 213 bits (542), Expect = 6e-56
Identities = 100/160 (62%), Positives = 132/160 (82%), Gaps = 1/160 (0%)
Query: 1 MEKLRRVLSGQDDEEQGLTAQVLDASSLSFNTRLKWFAICFVCGVFFSILGTGLLWLPG- 59
M+KL++VLSGQD E++ ++V++ASSLS++TR+K F CF G+ S+LGT LLW+P
Sbjct: 1 MDKLKKVLSGQDTEDRSGLSEVVEASSLSWSTRIKGFIACFAIGILCSLLGTVLLWVPRK 60
Query: 60 GIKLFAVFYTLGNLAALASTCFLMGPVKQLKKMFEATRLLATIVMLLCFIFTLCAALWWH 119
G+ LFAVFYT GN+A++ ST FLMGPVKQLK+MFE TRL+ATI++LLCF TLC+A WWH
Sbjct: 61 GLHLFAVFYTFGNIASIGSTIFLMGPVKQLKRMFEPTRLIATIMVLLCFALTLCSAFWWH 120
Query: 120 KKGLAVLFCILQFLSMTWYSLSYIPYARDAVIKCCSSLLS 159
KGLA++FCILQ L++TWYSLS+IP+ARDAV KC + L+
Sbjct: 121 NKGLALIFCILQSLALTWYSLSFIPFARDAVKKCFAVCLA 160
>gi|33413418 signal peptide peptidase 3 [Homo sapiens]
Length = 384
Score = 33.5 bits (75), Expect = 0.079
Identities = 22/100 (22%), Positives = 42/100 (42%)
Query: 44 GVFFSILGTGLLWLPGGIKLFAVFYTLGNLAALASTCFLMGPVKQLKKMFEATRLLATIV 103
G FS+LG G + +PG + F + Y A +C GP +M + + T++
Sbjct: 261 GSHFSMLGIGDIVMPGLLLCFVLRYDNYKKQASGDSCGAPGPANISGRMQKVSYFHCTLI 320
Query: 104 MLLCFIFTLCAALWWHKKGLAVLFCILQFLSMTWYSLSYI 143
+ T A H+ L ++ F + +++Y+
Sbjct: 321 GYFVGLLTATVASRIHRAAQPALLYLVPFTLLPLLTMAYL 360
>gi|13994190 frizzled 8 [Homo sapiens]
Length = 694
Score = 32.3 bits (72), Expect = 0.18
Identities = 16/68 (23%), Positives = 32/68 (47%), Gaps = 12/68 (17%)
Query: 83 MGPVKQLKKMFEATRLLATIVMLLCFIFTLCAALWWHKKGLAVLFCILQFLSMTWYSLSY 142
+G V+Q + L T+V LL + F + +++WW LS+TW+ +
Sbjct: 379 LGAVEQHVRYETTGPALCTVVFLLVYFFGMASSIWW------------VILSLTWFLAAG 426
Query: 143 IPYARDAV 150
+ + +A+
Sbjct: 427 MKWGNEAI 434
>gi|27894385 frizzled 5 precursor [Homo sapiens]
Length = 585
Score = 31.2 bits (69), Expect = 0.39
Identities = 14/52 (26%), Positives = 26/52 (50%), Gaps = 12/52 (23%)
Query: 99 LATIVMLLCFIFTLCAALWWHKKGLAVLFCILQFLSMTWYSLSYIPYARDAV 150
L TIV LL + F + +++WW LS+TW+ + + + +A+
Sbjct: 314 LCTIVFLLVYFFGMASSIWW------------VILSLTWFLAAGMKWGNEAI 353
>gi|31542731 major facilitator superfamily domain containing 7 [Homo
sapiens]
Length = 559
Score = 31.2 bits (69), Expect = 0.39
Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 11/90 (12%)
Query: 65 AVFYTLGNLAALASTCFLMGP-VKQLKKMFEATRLLATIVMLLCFIFTLCAALWWHKKGL 123
A+F T G L ALA +GP V + K EAT++ + L C F L + L L
Sbjct: 288 ALFITFGILGALA-----LGPYVDRTKHFTEATKIGLCLFSLACVPFALVSQLQGQTLAL 342
Query: 124 AVLFCILQFLSMTWYSLSYIPYARDAVIKC 153
A +L + S P A + ++C
Sbjct: 343 AATCSLLGL-----FGFSVGPVAMELAVEC 367
>gi|30039714 otopetrin 2 [Homo sapiens]
Length = 562
Score = 28.1 bits (61), Expect = 3.3
Identities = 23/100 (23%), Positives = 37/100 (37%), Gaps = 13/100 (13%)
Query: 43 CGVFFSILGTGLLWLPGGIKLFAVFYTLGNLAALASTCFLMGPVKQLKKMFEATRLLATI 102
C V + G +WL GG+ LF + L F G + A ++L +
Sbjct: 89 CAVPYRDAHAGPIWLRGGLVLFGI-------CTLIMDVFKTGYYSSFFECQSAIKILHPL 141
Query: 103 VMLLCFIFTLCAALWWHKKGLAVLFCILQFLSMTWYSLSY 142
+ + F+ LW K C+ L +TW L +
Sbjct: 142 IQAV-FVIIQTYFLWVSAKD-----CVHVHLDLTWCGLMF 175
>gi|225637544 olfactory receptor, family 56, subfamily A, member 5
[Homo sapiens]
Length = 313
Score = 27.7 bits (60), Expect = 4.3
Identities = 26/106 (24%), Positives = 42/106 (39%), Gaps = 5/106 (4%)
Query: 56 WLPGGIKLFAVFYTLGNLAALASTCFLMGPVKQLKKMFEATRLLATIVMLLCFIFTLCAA 115
WL + L + +G A L T +L + Q + L IV+ L I + A
Sbjct: 29 WLSLPLSLLFLL-AMGANATLLITIYLEASLHQPLYYLLSLLSLLDIVLCLTVIPKVLAI 87
Query: 116 LWWHKKGLAVLFCILQFLSM----TWYSLSYIPYARDAVIKCCSSL 157
W+ + ++ C LQ M T S +++ A D + C L
Sbjct: 88 FWFDLRSISFPACFLQVFIMNSFLTMESCTFMIMAYDRYVAICKPL 133
>gi|169202671 PREDICTED: olfactory receptor, family 56, subfamily A,
member 5 [Homo sapiens]
Length = 313
Score = 27.7 bits (60), Expect = 4.3
Identities = 26/106 (24%), Positives = 42/106 (39%), Gaps = 5/106 (4%)
Query: 56 WLPGGIKLFAVFYTLGNLAALASTCFLMGPVKQLKKMFEATRLLATIVMLLCFIFTLCAA 115
WL + L + +G A L T +L + Q + L IV+ L I + A
Sbjct: 29 WLSLPLSLLFLL-AMGANATLLITIYLEASLHQPLYYLLSLLSLLDIVLCLTVIPKVLAI 87
Query: 116 LWWHKKGLAVLFCILQFLSM----TWYSLSYIPYARDAVIKCCSSL 157
W+ + ++ C LQ M T S +++ A D + C L
Sbjct: 88 FWFDLRSISFPACFLQVFIMNSFLTMESCTFMIMAYDRYVAICKPL 133
>gi|89034551 PREDICTED: olfactory receptor, family 56, subfamily A,
member 5 [Homo sapiens]
Length = 313
Score = 27.7 bits (60), Expect = 4.3
Identities = 26/106 (24%), Positives = 42/106 (39%), Gaps = 5/106 (4%)
Query: 56 WLPGGIKLFAVFYTLGNLAALASTCFLMGPVKQLKKMFEATRLLATIVMLLCFIFTLCAA 115
WL + L + +G A L T +L + Q + L IV+ L I + A
Sbjct: 29 WLSLPLSLLFLL-AMGANATLLITIYLEASLHQPLYYLLSLLSLLDIVLCLTVIPKVLAI 87
Query: 116 LWWHKKGLAVLFCILQFLSM----TWYSLSYIPYARDAVIKCCSSL 157
W+ + ++ C LQ M T S +++ A D + C L
Sbjct: 88 FWFDLRSISFPACFLQVFIMNSFLTMESCTFMIMAYDRYVAICKPL 133
>gi|239744276 PREDICTED: olfactory receptor, family 56, subfamily A,
member 5 [Homo sapiens]
Length = 313
Score = 27.7 bits (60), Expect = 4.3
Identities = 26/106 (24%), Positives = 42/106 (39%), Gaps = 5/106 (4%)
Query: 56 WLPGGIKLFAVFYTLGNLAALASTCFLMGPVKQLKKMFEATRLLATIVMLLCFIFTLCAA 115
WL + L + +G A L T +L + Q + L IV+ L I + A
Sbjct: 29 WLSLPLSLLFLL-AMGANATLLITIYLEASLHQPLYYLLSLLSLLDIVLCLTVIPKVLAI 87
Query: 116 LWWHKKGLAVLFCILQFLSM----TWYSLSYIPYARDAVIKCCSSL 157
W+ + ++ C LQ M T S +++ A D + C L
Sbjct: 88 FWFDLRSISFPACFLQVFIMNSFLTMESCTFMIMAYDRYVAICKPL 133
>gi|62526033 ATP-binding cassette, sub-family G, member 2 [Homo
sapiens]
Length = 655
Score = 27.3 bits (59), Expect = 5.6
Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 12/109 (11%)
Query: 38 AICFVCGVFFSILGTGLLWLPGGIKLFAVFYTLGNLAALASTCFLMGPVKQLKKMFEATR 97
+I F C V+F + GL P F + +TL +A AS+ L Q +
Sbjct: 486 SIIFTCIVYFML---GLK--PKADAFFVMMFTLMMVAYSASSMALAIAAGQ------SVV 534
Query: 98 LLATIVMLLCFIFTLC-AALWWHKKGLAVLFCILQFLSMTWYSLSYIPY 145
+AT++M +CF+F + + L + +A LQ+ S+ Y + + +
Sbjct: 535 SVATLLMTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQH 583
>gi|31317278 WD repeat domain 20 isoform 3 [Homo sapiens]
Length = 508
Score = 27.3 bits (59), Expect = 5.6
Identities = 17/46 (36%), Positives = 23/46 (50%), Gaps = 2/46 (4%)
Query: 52 TGLLWLPGGIKLFAVFYTLGN--LAALASTCFLMGPVKQLKKMFEA 95
T + W+PG LF V ++ GN L + TC P QL K E+
Sbjct: 92 TCVKWVPGSESLFLVAHSSGNMYLYNVEHTCGTTAPHYQLLKQGES 137
>gi|31317276 WD repeat domain 20 isoform 4 [Homo sapiens]
Length = 445
Score = 27.3 bits (59), Expect = 5.6
Identities = 17/46 (36%), Positives = 23/46 (50%), Gaps = 2/46 (4%)
Query: 52 TGLLWLPGGIKLFAVFYTLGN--LAALASTCFLMGPVKQLKKMFEA 95
T + W+PG LF V ++ GN L + TC P QL K E+
Sbjct: 29 TCVKWVPGSESLFLVAHSSGNMYLYNVEHTCGTTAPHYQLLKQGES 74
>gi|31317274 WD repeat domain 20 isoform 1 [Homo sapiens]
Length = 581
Score = 27.3 bits (59), Expect = 5.6
Identities = 17/46 (36%), Positives = 23/46 (50%), Gaps = 2/46 (4%)
Query: 52 TGLLWLPGGIKLFAVFYTLGN--LAALASTCFLMGPVKQLKKMFEA 95
T + W+PG LF V ++ GN L + TC P QL K E+
Sbjct: 153 TCVKWVPGSESLFLVAHSSGNMYLYNVEHTCGTTAPHYQLLKQGES 198
>gi|31317280 WD repeat domain 20 isoform 2 [Homo sapiens]
Length = 569
Score = 27.3 bits (59), Expect = 5.6
Identities = 17/46 (36%), Positives = 23/46 (50%), Gaps = 2/46 (4%)
Query: 52 TGLLWLPGGIKLFAVFYTLGN--LAALASTCFLMGPVKQLKKMFEA 95
T + W+PG LF V ++ GN L + TC P QL K E+
Sbjct: 153 TCVKWVPGSESLFLVAHSSGNMYLYNVEHTCGTTAPHYQLLKQGES 198
>gi|53933287 olfactory receptor, family 5, subfamily K, member 4
[Homo sapiens]
Length = 321
Score = 27.3 bits (59), Expect = 5.6
Identities = 17/53 (32%), Positives = 25/53 (47%), Gaps = 1/53 (1%)
Query: 63 LFAVFYTLGNLAALASTCFLMGPVKQLKKMFEATRLLATIVMLLCFIFTLCAA 115
L ++ LGNLA + S C K L+ F R+++ + F F LC A
Sbjct: 56 LTPMYIFLGNLALMDSCCSCAVTPKMLENFFSEDRIISLYECMAQFYF-LCLA 107
>gi|5454070 solute carrier family 9 (sodium/hydrogen exchanger),
member 6 isoform b [Homo sapiens]
Length = 669
Score = 26.9 bits (58), Expect = 7.4
Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 8/85 (9%)
Query: 65 AVFYTLGNLAALASTCFLMGP--------VKQLKKMFEATRLLATIVMLLCFIFTLCAAL 116
A+F ++G + S F MG V + K+ E L + L+ + L A
Sbjct: 287 AMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLLETGLFFLMSWSTFLLAEA 346
Query: 117 WWHKKGLAVLFCILQFLSMTWYSLS 141
W +AVLFC + T+ +LS
Sbjct: 347 WGFTGVVAVLFCGITQAHYTYNNLS 371
>gi|110227626 solute carrier family 9 (sodium/hydrogen exchanger),
member 6 isoform a [Homo sapiens]
Length = 701
Score = 26.9 bits (58), Expect = 7.4
Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 8/85 (9%)
Query: 65 AVFYTLGNLAALASTCFLMGP--------VKQLKKMFEATRLLATIVMLLCFIFTLCAAL 116
A+F ++G + S F MG V + K+ E L + L+ + L A
Sbjct: 319 AMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLLETGLFFLMSWSTFLLAEA 378
Query: 117 WWHKKGLAVLFCILQFLSMTWYSLS 141
W +AVLFC + T+ +LS
Sbjct: 379 WGFTGVVAVLFCGITQAHYTYNNLS 403
>gi|115270955 olfactory receptor, family 5, subfamily K, member 1
[Homo sapiens]
Length = 308
Score = 26.9 bits (58), Expect = 7.4
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 15/80 (18%)
Query: 45 VFFSILGTGLLWLPGGIKLFAVFYT-----------LGNLAALASTCFLMGPVKQLKKMF 93
VFF+I L+ + G I L A+ +T LGNLA + S C K L+ F
Sbjct: 30 VFFAIY---LITVVGNISLVALIFTHRRLHTPMYIFLGNLALVDSCCACAITPKMLENFF 86
Query: 94 EATRLLATIVMLLCFIFTLC 113
+ ++ + F F LC
Sbjct: 87 SENKRISLYECAVQFYF-LC 105
>gi|47679099 Kazal type serine protease inhibitor 5-like 2 [Homo
sapiens]
Length = 97
Score = 26.9 bits (58), Expect = 7.4
Identities = 12/51 (23%), Positives = 25/51 (49%)
Query: 89 LKKMFEATRLLATIVMLLCFIFTLCAALWWHKKGLAVLFCILQFLSMTWYS 139
+ K F LL+ I++ L WW +G+ + C + ++++WY+
Sbjct: 1 MAKSFPVFSLLSFILIHLVLSSVSGPRHWWPPRGIIKVKCPYEKVNLSWYN 51
>gi|53933278 olfactory receptor, family 5, subfamily K, member 3
[Homo sapiens]
Length = 321
Score = 26.6 bits (57), Expect = 9.6
Identities = 31/113 (27%), Positives = 48/113 (42%), Gaps = 20/113 (17%)
Query: 14 EEQGLTAQVLDASSLSFNTRLKWFAICFVCGVFFSILGTGLLWLPGGIKLFAVFYT---- 69
E L A+ + + +++ +LK + FV VFF+I L+ + G I L A+ Y
Sbjct: 4 ENHSLIAEFI-LTGFTYHPKLK--TVLFV--VFFAIY---LITMVGNIGLVALIYIEQRL 55
Query: 70 -------LGNLAALASTCFLMGPVKQLKKMFEATRLLATIVMLLCFIFTLCAA 115
LGNL + S C K L+ F + + + F F LC A
Sbjct: 56 HTPMYIFLGNLVLMDSCCSSAITPKMLENFFSEDKRITLYECMAQFYF-LCLA 107
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.332 0.142 0.464
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,371,199
Number of Sequences: 37866
Number of extensions: 191778
Number of successful extensions: 640
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 632
Number of HSP's gapped (non-prelim): 23
length of query: 159
length of database: 18,247,518
effective HSP length: 94
effective length of query: 65
effective length of database: 14,688,114
effective search space: 954727410
effective search space used: 954727410
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (22.0 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.