Search of human proteins with 21536404

Search of human proteins with 21536404

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens]
         (506 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens]           1020   0.0  
gi|21536402 bridging integrator 1 isoform 2 [Homo sapiens]            999   0.0  
gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens]            941   0.0  
gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens]            920   0.0  
gi|21536400 bridging integrator 1 isoform 1 [Homo sapiens]            881   0.0  
gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens]            868   0.0  
gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens]            858   0.0  
gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens]             838   0.0  
gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens]            819   0.0  
gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens]           739   0.0  
gi|21536423 amphiphysin isoform 2 [Homo sapiens]                      353   2e-97
gi|4502081 amphiphysin isoform 1 [Homo sapiens]                       353   2e-97
gi|49472835 bridging integrator 2 [Homo sapiens]                      304   1e-82
gi|154146199 sal-like 3 [Homo sapiens]                                 54   3e-07
gi|45439359 triple functional domain (PTPRF interacting) [Homo s...    51   3e-06
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap...    49   1e-05
gi|8923904 bridging integrator 3 [Homo sapiens]                        48   2e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni...    48   2e-05
gi|122937321 UNC homeobox [Homo sapiens]                               47   3e-05
gi|222418647 mucin 7, secreted precursor [Homo sapiens]                47   4e-05
gi|222418649 mucin 7, secreted precursor [Homo sapiens]                47   4e-05
gi|222418645 mucin 7, secreted precursor [Homo sapiens]                47   4e-05
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    47   4e-05
gi|110618248 mucin and cadherin-like isoform 1 [Homo sapiens]          47   4e-05
gi|154759259 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) ...    47   5e-05
gi|194595509 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) ...    47   5e-05
gi|33286446 opioid growth factor receptor [Homo sapiens]               47   5e-05
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    47   5e-05
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             46   7e-05
gi|49640014 ubiquitin associated and SH3 domain containing, A sh...    46   7e-05

>gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens]
          Length = 506

 Score = 1020 bits (2637), Expect = 0.0
 Identities = 506/506 (100%), Positives = 506/506 (100%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
           AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300

Query: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSLPSGEPSAAEGTFAVSWP 360
           DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSLPSGEPSAAEGTFAVSWP
Sbjct: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSLPSGEPSAAEGTFAVSWP 360

Query: 361 SQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVE 420
           SQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVE
Sbjct: 361 SQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVE 420

Query: 421 GGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVK 480
           GGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVK
Sbjct: 421 GGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVK 480

Query: 481 ESDWNQHKELEKCRGVFPENFTERVP 506
           ESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 481 ESDWNQHKELEKCRGVFPENFTERVP 506


>gi|21536402 bridging integrator 1 isoform 2 [Homo sapiens]
          Length = 550

 Score =  999 bits (2582), Expect = 0.0
 Identities = 506/550 (92%), Positives = 506/550 (92%), Gaps = 44/550 (8%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
           AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300

Query: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ-------------------------- 334
           DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ                          
Sbjct: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQASLLDLDFDPLPPVTS 360

Query: 335 ------------------PTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASE 376
                             PTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASE
Sbjct: 361 PVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASE 420

Query: 377 VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMF 436
           VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMF
Sbjct: 421 VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMF 480

Query: 437 KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV 496
           KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV
Sbjct: 481 KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV 540

Query: 497 FPENFTERVP 506
           FPENFTERVP
Sbjct: 541 FPENFTERVP 550


>gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens]
          Length = 475

 Score =  941 bits (2433), Expect = 0.0
 Identities = 475/506 (93%), Positives = 475/506 (93%), Gaps = 31/506 (6%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 269

Query: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSLPSGEPSAAEGTFAVSWP 360
           DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSLPSGEPSAAEGTFAVSWP
Sbjct: 270 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSLPSGEPSAAEGTFAVSWP 329

Query: 361 SQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVE 420
           SQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVE
Sbjct: 330 SQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVE 389

Query: 421 GGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVK 480
           GGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVK
Sbjct: 390 GGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVK 449

Query: 481 ESDWNQHKELEKCRGVFPENFTERVP 506
           ESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 450 ESDWNQHKELEKCRGVFPENFTERVP 475


>gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens]
          Length = 518

 Score =  920 bits (2379), Expect = 0.0
 Identities = 475/549 (86%), Positives = 475/549 (86%), Gaps = 74/549 (13%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 269

Query: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ-------------------------- 334
           DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ                          
Sbjct: 270 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS 329

Query: 335 -----------------PTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEV 377
                            PTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEV
Sbjct: 330 LFEDTFVPEISVTTPSQPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEV 389

Query: 378 AGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFK 437
           AGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFK
Sbjct: 390 AGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFK 449

Query: 438 VQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVF 497
           VQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVF
Sbjct: 450 VQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVF 509

Query: 498 PENFTERVP 506
           PENFTERVP
Sbjct: 510 PENFTERVP 518


>gi|21536400 bridging integrator 1 isoform 1 [Homo sapiens]
          Length = 593

 Score =  881 bits (2276), Expect = 0.0
 Identities = 469/593 (79%), Positives = 477/593 (80%), Gaps = 87/593 (14%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
           AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300

Query: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ-----PTESPAGSLPSGEP------S 349
           DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ     P   P    PS E       S
Sbjct: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS 360

Query: 350 AAEGTF----AVSWPSQTAEPGP------------------AQPAEASEVAG-------- 379
             E TF    +V+ PSQ   PGP                    P +A   +G        
Sbjct: 361 LFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLW 420

Query: 380 -GTQPAAGAQEPGETAAS------------------------------------------ 396
             T+  AG+   GE +A+                                          
Sbjct: 421 EPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET 480

Query: 397 ---EAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 453
              EAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ
Sbjct: 481 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 540

Query: 454 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 506
           LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 541 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 593


>gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens]
          Length = 482

 Score =  868 bits (2242), Expect = 0.0
 Identities = 447/513 (87%), Positives = 453/513 (88%), Gaps = 38/513 (7%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 269

Query: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ-----PTESPAGSLPSGEPSAAE--G 353
           DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ     P   P    PS E    +   
Sbjct: 270 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS 329

Query: 354 TFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPA 413
            F  ++  + +   P+QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPA
Sbjct: 330 LFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPA 389

Query: 414 TVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDE 473
           TVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDE
Sbjct: 390 TVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDE 449

Query: 474 GWLMGVKESDWNQHKELEKCRGVFPENFTERVP 506
           GWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 450 GWLMGVKESDWNQHKELEKCRGVFPENFTERVP 482


>gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens]
          Length = 497

 Score =  858 bits (2216), Expect = 0.0
 Identities = 447/528 (84%), Positives = 453/528 (85%), Gaps = 53/528 (10%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP--------------- 285
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP               
Sbjct: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPRKKSKLFSRLRRKKN 269

Query: 286 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ-----PTESPA 340
           SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ     P   P 
Sbjct: 270 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPP 329

Query: 341 GSLPSGEPSAAE--GTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEA 398
              PS E    +    F  ++  + +   P+QPAEASEVAGGTQPAAGAQEPGETAASEA
Sbjct: 330 KHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEA 389

Query: 399 ASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGD 458
           ASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGD
Sbjct: 390 ASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGD 449

Query: 459 VVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 506
           VVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 450 VVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 497


>gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens]
          Length = 454

 Score =  838 bits (2165), Expect = 0.0
 Identities = 438/521 (84%), Positives = 438/521 (84%), Gaps = 82/521 (15%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP--------------- 285
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP               
Sbjct: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPRKKSKLFSRLRRKKN 269

Query: 286 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSLPS 345
           SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQP E        
Sbjct: 270 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAE-------- 321

Query: 346 GEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPA 405
                                       ASEVAGGTQPAAGAQEPGETAASEAASSSLPA
Sbjct: 322 ----------------------------ASEVAGGTQPAAGAQEPGETAASEAASSSLPA 353

Query: 406 VVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPF 465
           VVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPF
Sbjct: 354 VVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPF 413

Query: 466 QNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 506
           QNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 414 QNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 454


>gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens]
          Length = 439

 Score =  819 bits (2116), Expect = 0.0
 Identities = 427/506 (84%), Positives = 429/506 (84%), Gaps = 67/506 (13%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 269

Query: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSLPSGEPSAAEGTFAVSWP 360
           DGSPAATPEIRVNH                                EP  A G    + P
Sbjct: 270 DGSPAATPEIRVNH--------------------------------EPEPAGG----ATP 293

Query: 361 SQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVE 420
             T    P+QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVE
Sbjct: 294 GATLPKSPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVE 353

Query: 421 GGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVK 480
           GGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVK
Sbjct: 354 GGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVK 413

Query: 481 ESDWNQHKELEKCRGVFPENFTERVP 506
           ESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 414 ESDWNQHKELEKCRGVFPENFTERVP 439


>gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens]
          Length = 409

 Score =  739 bits (1909), Expect = 0.0
 Identities = 393/506 (77%), Positives = 396/506 (78%), Gaps = 97/506 (19%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 269

Query: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSLPSGEPSAAEGTFAVSWP 360
           DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ                       S P
Sbjct: 270 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQS----------------------SLP 307

Query: 361 SQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVE 420
           +   E  PA       V G  +  +GA                                 
Sbjct: 308 AVVVETFPA------TVNGTVEGGSGA--------------------------------- 328

Query: 421 GGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVK 480
                GRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVK
Sbjct: 329 -----GRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVK 383

Query: 481 ESDWNQHKELEKCRGVFPENFTERVP 506
           ESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 384 ESDWNQHKELEKCRGVFPENFTERVP 409


>gi|21536423 amphiphysin isoform 2 [Homo sapiens]
          Length = 653

 Score =  353 bits (906), Expect = 2e-97
 Identities = 184/332 (55%), Positives = 226/332 (68%), Gaps = 35/332 (10%)

Query: 9   VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
           +  G  A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q  EGTRLQ++LR Y
Sbjct: 4   IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63

Query: 69  LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
           LA++K M EAS KL E L EVYEPDW GR++   + E  D+LW D+HQKLVD +LLT+DT
Sbjct: 64  LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123

Query: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEKAAPQWCQG 188
           YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+K               
Sbjct: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISK--------------- 168

Query: 189 KLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGL 248
                           AEEE  KAQKVFEE NVDLQEELPSLW+ RVGFYVNTF++++ L
Sbjct: 169 ----------------AEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSL 212

Query: 249 EENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP-DGSPAAT 307
           E  FHKE++ L   L +V+  L  QH    FT++  PSD+ P +  K+PSPP + SP  +
Sbjct: 213 EAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPS 272

Query: 308 PEIRVNHEPEPAGGATPGATLPKSPSQPTESP 339
           P    NH   P   A+P    P+SPSQ  + P
Sbjct: 273 PTASPNHTLAP---ASPAPARPRSPSQTRKGP 301



 Score =  114 bits (285), Expect = 2e-25
 Identities = 77/233 (33%), Positives = 107/233 (45%), Gaps = 19/233 (8%)

Query: 285 PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSLP 344
           P  +A A      S  +G+P    E      P   G +   A   K  ++ TE    + P
Sbjct: 427 PGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEA---KIGTETTEGAESAQP 483

Query: 345 SGEPSAAEGTFAVSWPSQTAEPGPAQPAEA-SEVAGGTQPAAGAQEPGETAASEAASSSL 403
             E   A        PS   EP      E  +E+  G +P    +E  E AA    +S  
Sbjct: 484 EAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEP----KETTEDAAPPGPTSET 539

Query: 404 PAVVVETFPATVNGTVEGGSGAGRLD-----------LPPGFMFKVQAQHDYTATDTDEL 452
           P +  E  P             G  D           LPPGF++KV+  HD+ A ++DEL
Sbjct: 540 PELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDEL 599

Query: 453 QLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERV 505
            L+ GDVVLV+P  +  +QD GWL+GVKESDW Q+++L   +G+FPENFT R+
Sbjct: 600 TLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRL 652


>gi|4502081 amphiphysin isoform 1 [Homo sapiens]
          Length = 695

 Score =  353 bits (906), Expect = 2e-97
 Identities = 184/332 (55%), Positives = 226/332 (68%), Gaps = 35/332 (10%)

Query: 9   VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
           +  G  A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q  EGTRLQ++LR Y
Sbjct: 4   IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63

Query: 69  LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
           LA++K M EAS KL E L EVYEPDW GR++   + E  D+LW D+HQKLVD +LLT+DT
Sbjct: 64  LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123

Query: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEKAAPQWCQG 188
           YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+K               
Sbjct: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISK--------------- 168

Query: 189 KLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGL 248
                           AEEE  KAQKVFEE NVDLQEELPSLW+ RVGFYVNTF++++ L
Sbjct: 169 ----------------AEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSL 212

Query: 249 EENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP-DGSPAAT 307
           E  FHKE++ L   L +V+  L  QH    FT++  PSD+ P +  K+PSPP + SP  +
Sbjct: 213 EAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPS 272

Query: 308 PEIRVNHEPEPAGGATPGATLPKSPSQPTESP 339
           P    NH   P   A+P    P+SPSQ  + P
Sbjct: 273 PTASPNHTLAP---ASPAPARPRSPSQTRKGP 301



 Score =  114 bits (285), Expect = 2e-25
 Identities = 77/233 (33%), Positives = 107/233 (45%), Gaps = 19/233 (8%)

Query: 285 PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSLP 344
           P  +A A      S  +G+P    E      P   G +   A   K  ++ TE    + P
Sbjct: 469 PGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEA---KIGTETTEGAESAQP 525

Query: 345 SGEPSAAEGTFAVSWPSQTAEPGPAQPAEA-SEVAGGTQPAAGAQEPGETAASEAASSSL 403
             E   A        PS   EP      E  +E+  G +P    +E  E AA    +S  
Sbjct: 526 EAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEP----KETTEDAAPPGPTSET 581

Query: 404 PAVVVETFPATVNGTVEGGSGAGRLD-----------LPPGFMFKVQAQHDYTATDTDEL 452
           P +  E  P             G  D           LPPGF++KV+  HD+ A ++DEL
Sbjct: 582 PELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDEL 641

Query: 453 QLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERV 505
            L+ GDVVLV+P  +  +QD GWL+GVKESDW Q+++L   +G+FPENFT R+
Sbjct: 642 TLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRL 694


>gi|49472835 bridging integrator 2 [Homo sapiens]
          Length = 565

 Score =  304 bits (779), Expect = 1e-82
 Identities = 196/472 (41%), Positives = 253/472 (53%), Gaps = 104/472 (22%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAE G  G  AG  A  VQKK +RAQEKVLQKLGKA ETKDE+FEQ   NF +Q  EG +
Sbjct: 1   MAE-GKAGGAAGLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHK 59

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           L KDL+ +L++VK MHE+SK+++E LQE+Y  +W G +E   I  NNDLLW DY +KL D
Sbjct: 60  LYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLAD 119

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QA+ TM+ Y+ QF +IK RIAKRGRKLVDYDSARHH E++Q AKKKDEAK AK       
Sbjct: 120 QAVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAK------- 172

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
                                   AEEE  KAQ VFE++N +L EELP L+NSR+G YV 
Sbjct: 173 ------------------------AEEEFNKAQTVFEDLNQELLEELPILYNSRIGCYVT 208

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSD------------- 287
            FQ+I+ L + F++EMSKLN NL +V+  LEKQH +  F VK   S              
Sbjct: 209 IFQNISNLRDVFYREMSKLNHNLYEVMSKLEKQHSNKVFVVKGLSSSSRRSLVISPPVRT 268

Query: 288 ---NAPAKGNKSPS-----------------PPD----------------------GSPA 305
              ++P     SPS                  PD                      GS A
Sbjct: 269 ATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKEGSEA 328

Query: 306 ATPEIRVNHEPEPA----GGATPGATLPKS-------PSQPTESPAGSL-PSGEPSAAEG 353
           ++ E     EP PA      A P  T  ++       PS  T SP G+L PSG+PS++  
Sbjct: 329 SSSE---EDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSS-- 383

Query: 354 TFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPA 405
              V   ++TA  G  QP + + +   + P +    P  TA+   +S ++P+
Sbjct: 384 ATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPS 435



 Score = 29.3 bits (64), Expect = 8.8
 Identities = 26/88 (29%), Positives = 30/88 (34%), Gaps = 15/88 (17%)

Query: 284 QPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSL 343
           QP   A  +   +P      P+  P  R    P P+ G          PS PT S  GS 
Sbjct: 400 QPKKRASIQRTSAP------PSRPPPPRATASPRPSSG--------NIPSSPTASGGGSP 445

Query: 344 PSGEPSAAEGTFAVSWPSQTAEPGPAQP 371
            S   S   GT A    S    P P  P
Sbjct: 446 TSPRASLGTGT-ASPRTSLEVSPNPEPP 472


>gi|154146199 sal-like 3 [Homo sapiens]
          Length = 1300

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 47/132 (35%), Positives = 62/132 (46%), Gaps = 14/132 (10%)

Query: 295 KSPSPPDGSPAATPEIRVNHEPEPAGGATPG-ATLPKSPSQPTESPAGSLPSGEPSAAEG 353
           + P  P  SPAA P       P PA    PG A LP S   P  + AGS P+  P+A EG
Sbjct: 235 RPPPRPSLSPAAAPSA-----PGPAPSQLPGLAALPLSAGAPAAAIAGSGPAA-PAAFEG 288

Query: 354 TFAVSWPSQTAEP--GPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETF 411
              +S P   A    GPA+P+  +  +    PAA A  P    A ++A+SS P     T 
Sbjct: 289 AQPLSRPESGASTPGGPAEPSAPAAPSAAPAPAAPAPAP----APQSAASSQPQ-SASTP 343

Query: 412 PATVNGTVEGGS 423
           PA   G++ G +
Sbjct: 344 PALAPGSLLGAA 355



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 46/190 (24%), Positives = 63/190 (33%), Gaps = 66/190 (34%)

Query: 282 KAQPSDNAPAKGNKSPSPPDGSPA------ATPEIRVNHEP------------------- 316
           +A+P D  PA   ++P PP  +PA        P   V  E                    
Sbjct: 130 EAEPMDAEPAGDTRAPRPPPAAPAPPTPAYGAPSTNVTLEALLSTKVAVAQFSQGARAAG 189

Query: 317 -EPAGGATPGATLP-------------------------------KSPSQPTESPA---- 340
              AGG    A +P                               + P +P+ SPA    
Sbjct: 190 GSGAGGGVAAAAVPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPS 249

Query: 341 --GSLPSGEPSAAEGTFAVSWPSQT-AEPGPAQPAEASEVAGGTQPAAGAQEPGETA--A 395
             G  PS  P  A    +   P+   A  GPA PA        ++P +GA  PG  A  +
Sbjct: 250 APGPAPSQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESGASTPGGPAEPS 309

Query: 396 SEAASSSLPA 405
           + AA S+ PA
Sbjct: 310 APAAPSAAPA 319



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 29/96 (30%), Positives = 42/96 (43%), Gaps = 6/96 (6%)

Query: 286 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATL-PKSPSQPTESPAGSLP 344
           S  APA       P   +PAA    +    PE +G +TPG    P +P+ P+ +PA + P
Sbjct: 267 SAGAPAAAIAGSGP--AAPAAFEGAQPLSRPE-SGASTPGGPAEPSAPAAPSAAPAPAAP 323

Query: 345 SGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGG 380
           +  P+ A  + A S P   + P    P      A G
Sbjct: 324 A--PAPAPQSAASSQPQSASTPPALAPGSLLGAAPG 357



 Score = 33.9 bits (76), Expect = 0.36
 Identities = 42/143 (29%), Positives = 54/143 (37%), Gaps = 35/143 (24%)

Query: 287 DNAPAKGNKSPSP---PDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSL 343
           ++APA     P P   P+ SPA++P  R   E     GA  GA     P +    P  + 
Sbjct: 84  EDAPA-----PPPEDFPEPSPASSPSERAESEAAEEAGAE-GAEGEARPVEKEAEPMDAE 137

Query: 344 PSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSL 403
           P+G+  A               P PA PA  +       PA GA  P      EA  S+ 
Sbjct: 138 PAGDTRAPR-------------PPPAAPAPPT-------PAYGA--PSTNVTLEALLSTK 175

Query: 404 PAVVVETFPATVNGTVEGGSGAG 426
            AV       +      GGSGAG
Sbjct: 176 VAVA----QFSQGARAAGGSGAG 194



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 35/111 (31%), Positives = 43/111 (38%), Gaps = 14/111 (12%)

Query: 303 SPAATPEIRVNHEPEPA----GGATPGATLPKSPSQPTESPAGSLPSGEP-SAAEGTFAV 357
           SP+ATP  R    P PA       +PG    +S    T     SL  G P + AE    V
Sbjct: 543 SPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTKAE---PV 599

Query: 358 SWPSQTAEPGP----AQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLP 404
           S P   A  G     AQ + A     G   + G+  PG  A SE   +  P
Sbjct: 600 SLPCTNARAGDAPVGAQASAAPTSVDGAPTSLGS--PGLPAVSEQFKAQFP 648



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 38/150 (25%), Positives = 60/150 (40%), Gaps = 23/150 (15%)

Query: 239  VNTFQSIAGLE--ENFHKEMSKLNQNLNDVLVGLEKQH-GSNTFTVKAQPSDNAPAKGN- 294
            V + Q + GL+  EN   E  +L+ + +  +  LE +  GS   +  +     +PA  N 
Sbjct: 853  VMSCQQLTGLKSVENGSGESDRLSNDSSSAVGDLESRSAGSPALSESSSSQALSPAPSNG 912

Query: 295  ---KSPSPPDGSPAATPEIRVNHEPEPAGGATPGA-TLPKSPSQPTESP---------AG 341
               +S SP  G+P    EI +  E   +  A PG+   P       E+P          G
Sbjct: 913  ESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEAPFSLLFLSRERG 972

Query: 342  SLPS------GEPSAAEGTFAVSWPSQTAE 365
              PS      G+P A +    + + S T E
Sbjct: 973  KCPSTVCGVCGKPFACKSALEIHYRSHTKE 1002


>gi|45439359 triple functional domain (PTPRF interacting) [Homo
            sapiens]
          Length = 3097

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 57/246 (23%), Positives = 95/246 (38%), Gaps = 39/246 (15%)

Query: 271  EKQHGSNTFTVKAQPSDNAPAKGNKSPSP-PDGSPAA--------TPEIRVNHEPEPAGG 321
            +K  G++T      P   AP  G  +PS  P G+ A          P+++V   P   G 
Sbjct: 2364 DKMSGTSTPGPSLPPPGAAPEAGPSAPSRRPPGADAEGSEREAEPIPKMKVLESPRK-GA 2422

Query: 322  ATPGATLPKSPSQPTESPAGSLPSGEPSAAEGT-----FAVSWPSQTAEP-GPAQPAEAS 375
            A    + P +P++   +  G+LP G+P A   +      + + PS   EP  P+ P +  
Sbjct: 2423 ANASGSSPDAPAKDARASLGTLPLGKPRAGAASPLNSPLSSAVPSLGKEPFPPSSPLQKG 2482

Query: 376  EVAGGTQPAAGAQEPGE---TAASEAASSSLPAVV--------VETFPATVNGTVEGGSG 424
                 + PA+ A  PG       S++     P           + T  +    +V+    
Sbjct: 2483 GSFWSSIPASPASRPGSFTFPGDSDSLQRQTPRHAAPGKDTDRMSTCSSASEQSVQSTQS 2542

Query: 425  AGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIP---------FQNPEEQ---D 472
             G        +  +   HDYTA   DE+ +  G+VV ++          F+   +Q    
Sbjct: 2543 NGSESSSSSNISTMLVTHDYTAVKEDEINVYQGEVVQILASNQQNMFLVFRAATDQCPAA 2602

Query: 473  EGWLMG 478
            EGW+ G
Sbjct: 2603 EGWIPG 2608



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 43/199 (21%), Positives = 71/199 (35%), Gaps = 17/199 (8%)

Query: 233  SRVGFYVNTF---QSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNA 289
            SR G  V TF    S   + + +  E++++ +N  + L  L       T  ++ Q + + 
Sbjct: 2240 SRTGDVVETFILHSSSPSVRQTWIHEINQILENQRNFLNAL-------TSPIEYQRNHSG 2292

Query: 290  PAKGNKSPSPPDGSPAA---TPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSLPSG 346
               G  S     G  +     P     H   P+      +T    PS+  +      P  
Sbjct: 2293 GGGGGGSGGSGGGGGSGGGGAPSGGSGHSGGPSSCGGAPSTSRSRPSRIPQPVRHHPPVL 2352

Query: 347  EPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEP--GETAASEAASSSLP 404
              SAA         S T+ PGP+ P   +    G  P+A ++ P   +   SE  +  +P
Sbjct: 2353 VSSAASSQAEADKMSGTSTPGPSLPPPGAAPEAG--PSAPSRRPPGADAEGSEREAEPIP 2410

Query: 405  AVVVETFPATVNGTVEGGS 423
             + V   P        G S
Sbjct: 2411 KMKVLESPRKGAANASGSS 2429


>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
           sapiens]
          Length = 2524

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 59/230 (25%), Positives = 88/230 (38%), Gaps = 30/230 (13%)

Query: 245 IAGLEENFHKEMSKLNQNLNDVLVG-----LEKQHGSNTFTVKAQPSDNAPAKGNKSPSP 299
           ++G EE   +E   L+ + N+V  G         + S+T ++ +  ++ A   G   P P
Sbjct: 710 VSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKP 769

Query: 300 P-----DGSPAATP-----EIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSLPSGEPS 349
           P     DG P   P     +I    EP PA  AT   T P +P  P+  P    P     
Sbjct: 770 PATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPP----PVVPKE 825

Query: 350 AAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSS-LPAVVV 408
             E   A + P +  E    +P  A E+A  T     A+EP ++  +E A          
Sbjct: 826 EKEEETAAAPPVEEGE--EQKPPAAEELAVDT---GKAEEPVKSECTEEAEEGPAKGKDA 880

Query: 409 ETFPATVNGTV-----EGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 453
           E   AT  G +     EGGSG        G      +    +A + DE +
Sbjct: 881 EAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAE 930


>gi|8923904 bridging integrator 3 [Homo sapiens]
          Length = 253

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 60/224 (26%), Positives = 103/224 (45%), Gaps = 41/224 (18%)

Query: 53  KQLTEGTR-LQKDLRTYLASVKAMHEASKKLNECL--QEVYEPDWPGRDEANKI-AENND 108
           +QL E TR LQKD++    +  AM +++ K++  L    + E D   +D  N + A +  
Sbjct: 32  QQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQD---QDLLNMVTALDTA 88

Query: 109 LLWMD-YHQKLVDQALLTMDTYLGQF----PDIKSRIAKRGRKLVDYDSARHHYESLQTA 163
           +  MD ++Q+ V+Q   T+   L +F    P +   + +R + L DY         LQ  
Sbjct: 89  MKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDY-------RRLQAK 141

Query: 164 KKKDEAKIAKPVSLLEKAAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDL 223
            +K E K        EK  P   +               +QA EEL   ++ FE  N  L
Sbjct: 142 VEKYEEK--------EKTGPVLAK--------------LHQAREELRPVREDFEAKNRQL 179

Query: 224 QEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVL 267
            EE+P  + SR+ ++  +F+S+   +  ++ EM K+  +L+  L
Sbjct: 180 LEEMPRFYGSRLDYFQPSFESLIRAQVVYYSEMHKIFGDLSHQL 223


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 42/146 (28%), Positives = 61/146 (41%), Gaps = 13/146 (8%)

Query: 292  KGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAG--SLPSGEPS 349
            KG  + SPP G+P  TP       P+ + G  P    P  P+    SP G  +LP+  PS
Sbjct: 1298 KGGPATSPPKGAP--TPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS 1355

Query: 350  AAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVV-- 407
            +  G       + +++ GP  PA      GG      + + G    S     + PAV+  
Sbjct: 1356 SKGGP-----TTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPL 1410

Query: 408  -VETFPATVNGTVEGGSGAGRLDLPP 432
              +  PAT   T EG +   + DL P
Sbjct: 1411 SPKKAPAT-PVTREGAATPSKGDLTP 1435



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 38/126 (30%), Positives = 52/126 (41%), Gaps = 16/126 (12%)

Query: 285  PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSP--SQPTESPAG- 341
            P   AP     +P  P G PA +P         P G  TP A  P SP  S  T  P G 
Sbjct: 1282 PHKGAPNPAVVTPPSPKGGPATSP---------PKGAPTPPAATPPSPKGSPGTPPPKGA 1332

Query: 342  -SLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAAS 400
             + P+  P + +GT  +   + +++ GP  P   S   G T PAA     G  A +  + 
Sbjct: 1333 PTPPAVTPPSPKGTPTLPATTPSSKGGPTTP---SSKEGPTPPAATPSHKGGPAMTPPSP 1389

Query: 401  SSLPAV 406
               PA+
Sbjct: 1390 KRGPAI 1395



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 40/136 (29%), Positives = 46/136 (33%), Gaps = 21/136 (15%)

Query: 283  AQPSDN-APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAG 341
            A PS   AP     +P  P G PA          P P G  TP A  P SP      PA 
Sbjct: 955  ATPSPKWAPTPPAATPPSPKGGPAT---------PSPKGAPTPPAATPPSPKG---GPAT 1002

Query: 342  SLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASS 401
              P G P+      AV+ PS    P     A        T PAA    P  + A+     
Sbjct: 1003 PSPKGAPTPP----AVTPPSPKGSPA----ATPFPKGASTPPAATPPSPKGSPAATPLPK 1054

Query: 402  SLPAVVVETFPATVNG 417
              P     T P+   G
Sbjct: 1055 GAPTTPAATLPSPKGG 1070



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 36/136 (26%), Positives = 50/136 (36%), Gaps = 6/136 (4%)

Query: 275  GSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGG--ATPGATLPKSP 332
            G  T ++K  P+  A    +    P   SP   P       P P GG    P    P +P
Sbjct: 1070 GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTP 1129

Query: 333  SQPTESPAGSLPSGEPSAAEGTFAVSWPSQ---TAEPGPAQPAEASEVAGGTQPAAGAQE 389
            +    SP G L +  P  A  T A + PS     A P P + A  +  A    P  G   
Sbjct: 1130 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP-PPKGAPTTPAATPPSPKGGLAT 1188

Query: 390  PGETAASEAASSSLPA 405
            P    A    +++ P+
Sbjct: 1189 PSPKGAPTTPAATPPS 1204



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 35/131 (26%), Positives = 46/131 (35%), Gaps = 11/131 (8%)

Query: 285  PSDNAPAKGNKSPSPPDGS-----PAATPEIRVNHEPEPAGG--ATPGATLPKSPSQPTE 337
            P   AP     +P  P G      P   P       P P GG    P    P +P+    
Sbjct: 1121 PHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1180

Query: 338  SPAGSLPSGEPSAAEGTFAVSWPSQ---TAEPGPAQPAEASEVAGGTQPAAGAQEPGETA 394
            SP G L +  P  A  T A + PS     A P P + A  +  A    P  G   P    
Sbjct: 1181 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP-KGAPTTPAATPPSPKGGLATPSPKG 1239

Query: 395  ASEAASSSLPA 405
            A    +++ P+
Sbjct: 1240 APTTPAATPPS 1250



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 37/132 (28%), Positives = 49/132 (37%), Gaps = 11/132 (8%)

Query: 285  PSDNAPAKGNKSPSPPDGS-----PAATPEIRVNHEPEPAGG-ATPGAT-LPKSPSQPTE 337
            P   AP     +P  P G      P   P       P P GG ATP     P +P+    
Sbjct: 1144 PPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1203

Query: 338  SPAGSLPSGEPSAAEGTFAVSWPSQ---TAEPGPAQPAEASEVAGGTQPAAGAQEPGETA 394
            SP G L +  P  A  T A + PS     A P P + A  +  A    P  G   P    
Sbjct: 1204 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP-KGAPTTPAATPPSPKGGPATPPPKG 1262

Query: 395  ASEAASSSLPAV 406
            A    +++ P++
Sbjct: 1263 APTPPAATPPSL 1274



 Score = 37.4 bits (85), Expect = 0.032
 Identities = 31/116 (26%), Positives = 39/116 (33%), Gaps = 5/116 (4%)

Query: 289  APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS----PSQPTESPAGSLP 344
            APA    S SP        P+  +   P P G  TP A  P S    P+ P+   A + P
Sbjct: 908  APALSMTSSSPKKARATPAPK-GIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPP 966

Query: 345  SGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAAS 400
            +  P + +G  A   P     P  A P           P      P  T  S   S
Sbjct: 967  AATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGS 1022



 Score = 37.4 bits (85), Expect = 0.032
 Identities = 38/145 (26%), Positives = 50/145 (34%), Gaps = 30/145 (20%)

Query: 290  PAKGNKSP---SPPDGSPAATPEIRVNHEPEPAG--------GATPGATLPK-------S 331
            P KG  +P   +PP  SP  TP +         G        G TP A  P        +
Sbjct: 1328 PPKGAPTPPAVTPP--SPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMT 1385

Query: 332  PSQPTESPAGSLPSGEPSA----------AEGTFAVSWPSQTAEPGPAQPAEASEVAGGT 381
            P  P   PA   P G+P++          A  T      + T   G   P   + V+   
Sbjct: 1386 PPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKK 1445

Query: 382  QPAAGAQEPGETAASEAASSSLPAV 406
             PA  A + G    S     +LPAV
Sbjct: 1446 APATSAPKGGPATPSSKGDPTLPAV 1470



 Score = 37.0 bits (84), Expect = 0.042
 Identities = 43/136 (31%), Positives = 57/136 (41%), Gaps = 19/136 (13%)

Query: 285  PSDNAPA-KGNKSPSPPDGSPAATPEIRVNHEPEPAGGATP---GATLP--KSPSQPTES 338
            P+   P+ KG  +   P G+P  TP       P+ +  ATP   GA+ P   +P  P  S
Sbjct: 989  PAATPPSPKGGPATPSPKGAP--TPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGS 1046

Query: 339  PAGS-LPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEP-GETAAS 396
            PA + LP G P+    T A + PS   + GPA P   S     T PAA    P G  A  
Sbjct: 1047 PAATPLPKGAPT----TPAATLPS--PKGGPATP---SLKGAPTPPAATPPSPKGGPATP 1097

Query: 397  EAASSSLPAVVVETFP 412
                + +P       P
Sbjct: 1098 SPKGAPMPPAATPPSP 1113



 Score = 37.0 bits (84), Expect = 0.042
 Identities = 37/118 (31%), Positives = 50/118 (42%), Gaps = 18/118 (15%)

Query: 285  PSDNAPA-KGNKSPSPPDGSP---AATPEIRVNHEPEPAGGATPGATLPKSPSQPT--ES 338
            P+   P+ KG+    PP G+P   A TP       P P G  T  AT P S   PT   S
Sbjct: 1313 PAATPPSPKGSPGTPPPKGAPTPPAVTP-------PSPKGTPTLPATTPSSKGGPTTPSS 1365

Query: 339  PAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAAS 396
              G  P     + +G  A++ PS   + GPA P+   +    T PA     P +  A+
Sbjct: 1366 KEGPTPPAATPSHKGGPAMTPPS--PKRGPAIPSPKGD---PTSPAVIPLSPKKAPAT 1418



 Score = 36.2 bits (82), Expect = 0.072
 Identities = 37/129 (28%), Positives = 49/129 (37%), Gaps = 21/129 (16%)

Query: 286  SDNAPAKGNKSPSP--------PDGSP---AATPEIRVNHEPEPAGG-ATPGAT-LPKSP 332
            + ++P K   +P+P        P G+P   AATP       P P GG ATP     P  P
Sbjct: 914  TSSSPKKARATPAPKGIPASPSPKGAPTPPAATP-------PSPKGGPATPSPKWAPTPP 966

Query: 333  SQPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGE 392
            +    SP G   +  P  A    A + PS    P    P  A      T P+     P  
Sbjct: 967  AATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKG-SPAA 1025

Query: 393  TAASEAASS 401
            T   + AS+
Sbjct: 1026 TPFPKGAST 1034



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 38/164 (23%), Positives = 59/164 (35%), Gaps = 8/164 (4%)

Query: 275 GSNTFTVKAQPS-DNAPAKGNKSPSPPDGSPAATPEIRVNHE-----PEPAGGATPGATL 328
           G++T+T  A P  +   +   K+    +G+    P +    E     P P     P ATL
Sbjct: 665 GTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATL 724

Query: 329 PKSPSQPTESPAGSL-PSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGA 387
             +P  P   P+ SL P+G P   +    +S  S  A P  + P E      G    A +
Sbjct: 725 VLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALA-PVASSPKECPTEDSGASATASS 783

Query: 388 QEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLP 431
           +      A   +   +        P T  G+    +  G L  P
Sbjct: 784 KGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSP 827



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 41/149 (27%), Positives = 53/149 (35%), Gaps = 27/149 (18%)

Query: 282  KAQPSDNAPAKGNKSPSPPDGS--PAATPEIRVNHEPEPAGGATPGATLPKSPSQ----- 334
            K  P+   P +   +PS  + S  PA TP       P P     P A    SP +     
Sbjct: 1559 KKTPAIPTPKEAPATPSSKEASSPPAVTPST-YKGAPSPKELLIPPAVTSPSPKEAPTPP 1617

Query: 335  ------PTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQ 388
                  P + PA   P G P++   T     PS + +  P  PA  +   G T P A   
Sbjct: 1618 AVTPPSPEKGPATPAPKGTPTSPPVT-----PS-SLKDSPTSPASVTCKMGATVPQASKG 1671

Query: 389  EP---GETAASEA----ASSSLPAVVVET 410
             P   G TA  E     A  S P +   T
Sbjct: 1672 LPAKKGPTALKEVLVAPAPESTPIITAPT 1700



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 38/152 (25%), Positives = 53/152 (34%), Gaps = 23/152 (15%)

Query: 280  TVKAQPSDNAPAKGNKSPS------------PPDGSPAATPEIRVNHEPE-------PAG 320
            ++K  P+ +AP  G  +PS            P    P A  ++  +  P+       P G
Sbjct: 1442 SLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMG 1501

Query: 321  GATPGATLPKSPSQPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGG 380
              T  A +P SP    E PA      +P A   T        T  P  A    A  V   
Sbjct: 1502 APTLPAVIPSSPK---EVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSP 1558

Query: 381  TQ-PAAGAQEPGETAASEAASSSLPAVVVETF 411
             + PA    +      S   +SS PAV   T+
Sbjct: 1559 KKTPAIPTPKEAPATPSSKEASSPPAVTPSTY 1590



 Score = 33.1 bits (74), Expect = 0.61
 Identities = 43/144 (29%), Positives = 57/144 (39%), Gaps = 31/144 (21%)

Query: 296  SPSPPDGSPAATPEIRVNHEPEPAGG-ATP---GATLPKSPSQPTESPAGSL-------- 343
            +P+PP    AATP       P P GG ATP   GA +P  P+    SP G L        
Sbjct: 1079 APTPP----AATP-------PSPKGGPATPSPKGAPMP--PAATPPSPKGGLATPPHKGA 1125

Query: 344  ---PSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGA-QEPGETAASEAA 399
               P+  P + +G  A   P + A   PA    + +    T P  GA   P  T  S   
Sbjct: 1126 PTTPAATPPSPKGGLATP-PPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG 1184

Query: 400  SSSLPAVV-VETFPATVNGTVEGG 422
              + P+     T PA    + +GG
Sbjct: 1185 GLATPSPKGAPTTPAATPPSPKGG 1208



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 39/150 (26%), Positives = 55/150 (36%), Gaps = 22/150 (14%)

Query: 285 PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPS----QPTESPA 340
           P ++   +G+K       SP  TP       P P G  TP A  P SP      P E+P 
Sbjct: 837 PENSLSFQGSKDSPATTHSP--TP-------PSPKGAPTPSAVTPLSPKGVTLPPKETPT 887

Query: 341 GSL-----PSGEPS--AAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET 393
            S+     P   P+  A +   A+S  S + +   A PA    +     P      P  T
Sbjct: 888 PSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKG-IPASPSPKGAPTPPAAT 946

Query: 394 AASEAASSSLPAVV-VETFPATVNGTVEGG 422
             S     + P+     T PA    + +GG
Sbjct: 947 PPSPKGGPATPSPKWAPTPPAATPPSPKGG 976


>gi|122937321 UNC homeobox [Homo sapiens]
          Length = 531

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 49/195 (25%), Positives = 73/195 (37%), Gaps = 30/195 (15%)

Query: 249 EENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTV------KAQPSDNAPAKGNKSPSPPDG 302
           EE   KE+ K+ +        L K  G +  +        A  SD+    G  SP PP  
Sbjct: 190 EEIARKELEKMEKKKRKHEKKLLKSQGRHLHSPGGLSLHSAPSSDSDSGGGGLSPEPP-- 247

Query: 303 SPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSLPSGEPSAAEGTFAVSWPSQ 362
                       EP P     PGA    +      +PA   P GEP A        +PSQ
Sbjct: 248 ------------EPPPPAAKGPGA---HASGAAGTAPA---PPGEPPAPGTCDPAFYPSQ 289

Query: 363 TA----EPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGT 418
            +    +P P +PA+    + G   A  A E G     +A+  S+ +++ ++ P     +
Sbjct: 290 RSGAGPQPRPGRPADKDAASCGPGAAVAAVERGAAGLPKASPFSVESLLSDSPPRRKAAS 349

Query: 419 VEGGSGAGRLDLPPG 433
               + A  LD  PG
Sbjct: 350 NAAAAAAAGLDFAPG 364



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 30/120 (25%), Positives = 45/120 (37%), Gaps = 13/120 (10%)

Query: 297 PSPPDGSPAAT----PEIRVNHEPEPAGGATPGATLPK-------SPSQPTESPAGSLPS 345
           P+P D  PA      P  + +       G  P +   +       SP  P  +PA     
Sbjct: 404 PAPKDAPPAPAVPPAPPAQASFGAFSGPGGAPDSAFARRSPDAVASPGAPAPAPAPFRDL 463

Query: 346 GEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPA 405
              +A EG       + TA  GPA P  A     G +P + A+EP      E  +++ P+
Sbjct: 464 ASAAATEGGGGDCADAGTA--GPAPPPPAPSPRPGPRPPSPAEEPATCGVPEPGAAAGPS 521


>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 35/131 (26%), Positives = 56/131 (42%), Gaps = 14/131 (10%)

Query: 280 TVKAQPSDNAPAKGNKSP-SPPDGSPA-----------ATPEIRVNHEPEPAGGATPGAT 327
           T +A PS +AP +   +P +PP  +PA           A P       P P   + P  T
Sbjct: 198 TTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPET 257

Query: 328 --LPKSPSQPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAA 385
             +P +PS  T  P+ +    E +AA  T + + P+  + P P +   A      + P  
Sbjct: 258 TAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTT 317

Query: 386 GAQEPGETAAS 396
            A +  ET+A+
Sbjct: 318 LAPDTSETSAA 328



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 41/191 (21%), Positives = 67/191 (35%), Gaps = 12/191 (6%)

Query: 226 ELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHG---------- 275
           ++PS+        + T  ++  L +N     S+ N N +  +  L   +           
Sbjct: 110 QIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAP 169

Query: 276 -SNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ 334
            + + T  A PS +AP +   +P  P  +  A P      E   A   TP AT P  PS 
Sbjct: 170 PTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPE-TTAAPPTPPATTPAPPSS 228

Query: 335 PTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETA 394
                  + P    +      + S P +T    P   A   + +  + P      P   +
Sbjct: 229 SAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPS 288

Query: 395 ASEAASSSLPA 405
           A+  A  S PA
Sbjct: 289 ATTPAPPSSPA 299



 Score = 33.1 bits (74), Expect = 0.61
 Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 13/93 (13%)

Query: 280 TVKAQPSDNAPAKGNKSPSPP-----DGSPAATPEIRVNHEPEP-AGGATPGATLPKSPS 333
           T  A  S +AP +    P  P     D S A+ P       PE  A   TP AT P  PS
Sbjct: 244 TTPAPLSSSAPPETTAVPPTPSATTLDPSSASAP-------PETTAAPPTPSATTPAPPS 296

Query: 334 QPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEP 366
            P      + P   P+++  T A      +A P
Sbjct: 297 SPAPQETTAAPITTPNSSPTTLAPDTSETSAAP 329


>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 35/131 (26%), Positives = 56/131 (42%), Gaps = 14/131 (10%)

Query: 280 TVKAQPSDNAPAKGNKSP-SPPDGSPA-----------ATPEIRVNHEPEPAGGATPGAT 327
           T +A PS +AP +   +P +PP  +PA           A P       P P   + P  T
Sbjct: 198 TTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPET 257

Query: 328 --LPKSPSQPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAA 385
             +P +PS  T  P+ +    E +AA  T + + P+  + P P +   A      + P  
Sbjct: 258 TAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTT 317

Query: 386 GAQEPGETAAS 396
            A +  ET+A+
Sbjct: 318 LAPDTSETSAA 328



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 41/191 (21%), Positives = 67/191 (35%), Gaps = 12/191 (6%)

Query: 226 ELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHG---------- 275
           ++PS+        + T  ++  L +N     S+ N N +  +  L   +           
Sbjct: 110 QIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAP 169

Query: 276 -SNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ 334
            + + T  A PS +AP +   +P  P  +  A P      E   A   TP AT P  PS 
Sbjct: 170 PTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPE-TTAAPPTPPATTPAPPSS 228

Query: 335 PTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETA 394
                  + P    +      + S P +T    P   A   + +  + P      P   +
Sbjct: 229 SAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPS 288

Query: 395 ASEAASSSLPA 405
           A+  A  S PA
Sbjct: 289 ATTPAPPSSPA 299



 Score = 33.1 bits (74), Expect = 0.61
 Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 13/93 (13%)

Query: 280 TVKAQPSDNAPAKGNKSPSPP-----DGSPAATPEIRVNHEPEP-AGGATPGATLPKSPS 333
           T  A  S +AP +    P  P     D S A+ P       PE  A   TP AT P  PS
Sbjct: 244 TTPAPLSSSAPPETTAVPPTPSATTLDPSSASAP-------PETTAAPPTPSATTPAPPS 296

Query: 334 QPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEP 366
            P      + P   P+++  T A      +A P
Sbjct: 297 SPAPQETTAAPITTPNSSPTTLAPDTSETSAAP 329


>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 35/131 (26%), Positives = 56/131 (42%), Gaps = 14/131 (10%)

Query: 280 TVKAQPSDNAPAKGNKSP-SPPDGSPA-----------ATPEIRVNHEPEPAGGATPGAT 327
           T +A PS +AP +   +P +PP  +PA           A P       P P   + P  T
Sbjct: 198 TTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPET 257

Query: 328 --LPKSPSQPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAA 385
             +P +PS  T  P+ +    E +AA  T + + P+  + P P +   A      + P  
Sbjct: 258 TAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTT 317

Query: 386 GAQEPGETAAS 396
            A +  ET+A+
Sbjct: 318 LAPDTSETSAA 328



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 41/191 (21%), Positives = 67/191 (35%), Gaps = 12/191 (6%)

Query: 226 ELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHG---------- 275
           ++PS+        + T  ++  L +N     S+ N N +  +  L   +           
Sbjct: 110 QIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAP 169

Query: 276 -SNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ 334
            + + T  A PS +AP +   +P  P  +  A P      E   A   TP AT P  PS 
Sbjct: 170 PTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPE-TTAAPPTPPATTPAPPSS 228

Query: 335 PTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETA 394
                  + P    +      + S P +T    P   A   + +  + P      P   +
Sbjct: 229 SAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPS 288

Query: 395 ASEAASSSLPA 405
           A+  A  S PA
Sbjct: 289 ATTPAPPSSPA 299



 Score = 33.1 bits (74), Expect = 0.61
 Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 13/93 (13%)

Query: 280 TVKAQPSDNAPAKGNKSPSPP-----DGSPAATPEIRVNHEPEP-AGGATPGATLPKSPS 333
           T  A  S +AP +    P  P     D S A+ P       PE  A   TP AT P  PS
Sbjct: 244 TTPAPLSSSAPPETTAVPPTPSATTLDPSSASAP-------PETTAAPPTPSATTPAPPS 296

Query: 334 QPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEP 366
            P      + P   P+++  T A      +A P
Sbjct: 297 SPAPQETTAAPITTPNSSPTTLAPDTSETSAAP 329


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 63/279 (22%), Positives = 124/279 (44%), Gaps = 23/279 (8%)

Query: 1    MAEMGSKGVTAGKIASNVQKKLTRAQE----KVLQKLGKADETKDEQFEQCVQNFNKQLT 56
            + E   KG+   K A++++ +L   QE    +  QKL  +   +  Q E+   +  +Q  
Sbjct: 1296 LEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIR--QLEEEKNSLQEQQE 1353

Query: 57   EGTRLQKDL-RTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYH 115
            E    +K+L +  LA    + +  KK+++ L  +   +    +   K+ ++ + L     
Sbjct: 1354 EEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLE----EAKKKLLKDAEAL----S 1405

Query: 116  QKLVDQALLTMDTYLGQFPDIKSRIAKRGRKL-VDYDSARHHYESLQTAKKKDEAKIAKP 174
            Q+L ++AL        +    K+R+ +    L VD D  R    +L+  +KK +  +A+ 
Sbjct: 1406 QRLEEKALA-----YDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEE 1460

Query: 175  VSLLEKAAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSR 234
             S+  + A +  + + +A       L   +A EE ++A++ FE  N  L+ ++  L +S+
Sbjct: 1461 KSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSK 1520

Query: 235  --VGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 271
              VG  V+  +      E   +EM    + L D L   E
Sbjct: 1521 DDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATE 1559



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 39/208 (18%), Positives = 89/208 (42%), Gaps = 18/208 (8%)

Query: 28   KVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTYLASVK-AMHEASKKLNECL 86
            KVLQ++    E K ++ +  VQ  + +++EG RL+ +L    + ++  +   S  L E  
Sbjct: 1241 KVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAE 1300

Query: 87   QEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDTYLGQFPDIKSRIAKRGRK 146
            ++  +         +++ +  +LL  +  QK      L + + + Q  + K+ + ++   
Sbjct: 1301 KKGIKFAKDAASLESQLQDTQELLQEETRQK------LNLSSRIRQLEEEKNSLQEQQE- 1353

Query: 147  LVDYDSARHHYE--------SLQTAKKKDEAKIAKPVSLLEKAAPQWCQGKLQAHLVAQT 198
              + + AR + E         L   KKK +  +    SL E         +  +  + + 
Sbjct: 1354 --EEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEK 1411

Query: 199  NLLRNQAEEELIKAQKVFEEMNVDLQEE 226
             L  ++ E+   + Q+  +++ VDL  +
Sbjct: 1412 ALAYDKLEKTKNRLQQELDDLTVDLDHQ 1439


>gi|110618248 mucin and cadherin-like isoform 1 [Homo sapiens]
          Length = 845

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 49/176 (27%), Positives = 70/176 (39%), Gaps = 17/176 (9%)

Query: 275 GSNTFTVKAQPSDNAPAKGNKSPSPPDG---SPAATPEIRVNHEPEPAGG----ATPGAT 327
           G+ T  ++ Q S+  P   +  PSP  G    P  +    V   PEP+ G    ++ G T
Sbjct: 441 GTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTSTTSEVPRPPEPSQGPSTTSSGGGT 500

Query: 328 LPKSPSQPT-ESPAGSLPSGEPSAAEGT-FAVSWP----SQTAEPGPAQPAEAS-EVAGG 380
            P  PS  T   P  S P G P A   T    + P    +QT +PG +QP       +  
Sbjct: 501 GPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPMPPGVGTSTS 560

Query: 381 TQPAAGAQEPGETAASEAASSSLPAVVVETF--PATV-NGTVEGGSGAGRLDLPPG 433
            QPA  +    +T     +    P++   T   PAT   GT +         +PPG
Sbjct: 561 HQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMPPG 616



 Score = 37.0 bits (84), Expect = 0.042
 Identities = 38/160 (23%), Positives = 58/160 (36%), Gaps = 21/160 (13%)

Query: 270 LEKQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLP 329
           + K +G        +  +  P   +     PD      P     H+P+PA    P    P
Sbjct: 690 VHKHYGPRLKCCSGKAPEPQPQGFDNQAFLPDHKANWAPVPSPTHDPKPAEAPMPAEPAP 749

Query: 330 KSPSQPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQE 389
             P+ P  +P       EP AA            A  G +  A  S +    +P  G + 
Sbjct: 750 PGPASPGGAP-------EPPAA------------ARAGGSPTAVRSILTKERRPEGGYKA 790

Query: 390 P--GETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGR 427
              GE   +EA    L A  ++   A+ +G+ + G GAGR
Sbjct: 791 VWFGEDIGTEADVVVLNAPTLDVDGASDSGSGDEGEGAGR 830



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 37/136 (27%), Positives = 54/136 (39%), Gaps = 20/136 (14%)

Query: 297 PSPPDGSPAATPEIRVNHEPEPAGG-------ATPGATLPKSP----SQPTESPAGSLPS 345
           P+ P G  A TP+   +    P  G       ATP     ++P    SQP     G+  S
Sbjct: 532 PATPGGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTS 591

Query: 346 GEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEP-GETAASEAASSSLP 404
            +P+   G  A     QT E G +QP        GT  +     P G TA +    +S P
Sbjct: 592 HQPATPGGGTA-----QTPEAGTSQPMPPGM---GTSTSHQPTTPGGGTAQTPEPGTSQP 643

Query: 405 AVVVETFPATVNGTVE 420
             + ++ P++  G  E
Sbjct: 644 MPLSKSTPSSGGGPSE 659


>gi|154759259 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
           isoform 2 [Homo sapiens]
          Length = 2472

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 66/288 (22%), Positives = 119/288 (41%), Gaps = 25/288 (8%)

Query: 3   EMGSKGVTAGKIASN-VQKKLTRAQEKVLQKLGKADETKDEQFEQCV--QNFNKQLT--- 56
           E G   + AG  AS+ V++KLT   E+    L +  E + +Q+EQC+  Q F +      
Sbjct: 422 ESGQALLAAGHYASDEVREKLTVLSEERAALL-ELWELRRQQYEQCMDLQLFYRDTEQVD 480

Query: 57  ------EGTRLQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLL 110
                 E   L +DL   L SV+A+ +  +   + L    E      + A K+ +NN   
Sbjct: 481 NWMSKQEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNN--- 537

Query: 111 WMDYHQKLVDQALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAK 170
               H  + D A    D  L +   +  R  +R  +L D    +  +      K     K
Sbjct: 538 ----HYAMEDVAT-RRDALLSRRNALHERAMRRRAQLADSFHLQQFFRDSDELKSWVNEK 592

Query: 171 IAKPVSLLEKAAPQWCQGKLQAHLVAQTNLLRNQAE-EELIKAQKVFEEMNVDLQEELPS 229
           +        K  P   QGK+Q H   +  L  NQ+  + L KA +   ++N   ++E+ +
Sbjct: 593 MKTATDEAYKD-PSNLQGKVQKHQAFEAELSANQSRIDALEKAGQKLIDVNHYAKDEVAA 651

Query: 230 LWNSRVGFYVNTFQS--IAGLEENFHKEMSKLNQNLNDVLVGLEKQHG 275
             N  +  +    ++  + G++     +  + N+N+ D+ + L +  G
Sbjct: 652 RMNEVISLWKKLLEATELKGIKLREANQQQQFNRNVEDIELWLYEVEG 699


>gi|194595509 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
           isoform 1 [Homo sapiens]
          Length = 2477

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 66/288 (22%), Positives = 119/288 (41%), Gaps = 25/288 (8%)

Query: 3   EMGSKGVTAGKIASN-VQKKLTRAQEKVLQKLGKADETKDEQFEQCV--QNFNKQLT--- 56
           E G   + AG  AS+ V++KLT   E+    L +  E + +Q+EQC+  Q F +      
Sbjct: 422 ESGQALLAAGHYASDEVREKLTVLSEERAALL-ELWELRRQQYEQCMDLQLFYRDTEQVD 480

Query: 57  ------EGTRLQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLL 110
                 E   L +DL   L SV+A+ +  +   + L    E      + A K+ +NN   
Sbjct: 481 NWMSKQEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNN--- 537

Query: 111 WMDYHQKLVDQALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAK 170
               H  + D A    D  L +   +  R  +R  +L D    +  +      K     K
Sbjct: 538 ----HYAMEDVAT-RRDALLSRRNALHERAMRRRAQLADSFHLQQFFRDSDELKSWVNEK 592

Query: 171 IAKPVSLLEKAAPQWCQGKLQAHLVAQTNLLRNQAE-EELIKAQKVFEEMNVDLQEELPS 229
           +        K  P   QGK+Q H   +  L  NQ+  + L KA +   ++N   ++E+ +
Sbjct: 593 MKTATDEAYKD-PSNLQGKVQKHQAFEAELSANQSRIDALEKAGQKLIDVNHYAKDEVAA 651

Query: 230 LWNSRVGFYVNTFQS--IAGLEENFHKEMSKLNQNLNDVLVGLEKQHG 275
             N  +  +    ++  + G++     +  + N+N+ D+ + L +  G
Sbjct: 652 RMNEVISLWKKLLEATELKGIKLREANQQQQFNRNVEDIELWLYEVEG 699


>gi|33286446 opioid growth factor receptor [Homo sapiens]
          Length = 677

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 43/155 (27%), Positives = 57/155 (36%), Gaps = 21/155 (13%)

Query: 285 PSDNAPAKGNKSPSPPDGSPAATPEIRVNHE---PEPAG--GATPGATLPKSPSQPTESP 339
           P +  P   +++P P    PA         E   P PAG  G  P  +  ++P      P
Sbjct: 510 PKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGP 569

Query: 340 AGSLPSGEPSAAEGTF--------AVSWPSQTAEPGPA-----QPAEASEVAGGTQPAAG 386
           AG  P+  PS   G              PS+T  P PA     +PAE+     G +PA  
Sbjct: 570 AGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGP 629

Query: 387 A-QEPGETAASEAASSSLPAVVVETFPATVNGTVE 420
           A  EP E+ +     S  PA      PA      E
Sbjct: 630 AGDEPAESPSETPGPS--PAGPTRDEPAKAGEAAE 662



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 44/146 (30%), Positives = 56/146 (38%), Gaps = 15/146 (10%)

Query: 289 APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPK--SPSQPTESPAGSLPSG 346
           A A G        GSPA +   +  H        T G T PK  +P  P+E+P  S    
Sbjct: 470 AVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPS---- 525

Query: 347 EPSAAEGTFAVSWPSQTAEPGPA-----QPAEASEVAGGTQPAAGA-QEPGETAASEAAS 400
            P+   G      PS+T  P PA     +PAE+     G +PA  A  EP E+ +     
Sbjct: 526 -PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP 584

Query: 401 SSLPAVVVETFPATVNGTVEGGSGAG 426
           S  PA      PA       G   AG
Sbjct: 585 S--PAGPTRDEPAESPSETPGPRPAG 608



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 47/156 (30%), Positives = 59/156 (37%), Gaps = 26/156 (16%)

Query: 287 DNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAG--GATPGATLPKSPSQPTESPAGSLP 344
           D     G K  +P  GSP+ TP       P PAG  G  P  +  ++P      PAG  P
Sbjct: 503 DTEGRTGPKEGTP--GSPSETPG------PSPAGPAGDEPAESPSETPGPRPAGPAGDEP 554

Query: 345 SGEPS--------AAEGTFAVSWPSQTAEPGPA-----QPAEASEVAGGTQPAAGA-QEP 390
           +  PS           G      PS+T  P PA     +PAE+     G +PA  A  EP
Sbjct: 555 AESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEP 614

Query: 391 GETAASEAASSSLPAVVVETFPATVNGTVEGGSGAG 426
            E+ +        PA      PA       G S AG
Sbjct: 615 AESPSE--TPGPRPAGPAGDEPAESPSETPGPSPAG 648



 Score = 38.1 bits (87), Expect = 0.019
 Identities = 37/133 (27%), Positives = 52/133 (39%), Gaps = 20/133 (15%)

Query: 283 AQPSDNAPAKG-NKSPSPPDGSPAATPEIRVNHE---PEPAGGAT--PGATLPKSPSQPT 336
           A P+ + PA+  +++P P    PA         E   P PAG     P  +  ++P    
Sbjct: 547 AGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRP 606

Query: 337 ESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPA-------AGAQE 389
             PAG  P+  PS   G        + A P   +PAE+     G  PA       A A E
Sbjct: 607 AGPAGDEPAESPSETPG-------PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGE 659

Query: 390 PGETAASEAASSS 402
             E   +E  SS+
Sbjct: 660 AAELQDAEVESSA 672


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 40/136 (29%), Positives = 54/136 (39%), Gaps = 29/136 (21%)

Query: 289 APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTES----PAGSLP 344
           A A G    +P +G+P A PE      P PAG A PG   P+ P  P+      PAG  P
Sbjct: 68  AGAAGAGPAAPAEGAPGAAPE------PPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAP 121

Query: 345 ------------SGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAG------ 386
                       +G  +      AV+   + A  GPA+PA  + +A    P  G      
Sbjct: 122 PAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPG 181

Query: 387 -AQEPGETAASEAASS 401
               PG+ A   AA +
Sbjct: 182 PGPGPGKPAGPGAAQT 197



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 46/156 (29%), Positives = 59/156 (37%), Gaps = 20/156 (12%)

Query: 283 AQPSDNAPAKGNKSPSP-------PDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQP 335
           A P+  APA     P P       P G PA  P       P  A      A    +P+  
Sbjct: 259 AAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPA 318

Query: 336 TESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAA 395
              PAG   SG+P       A + P   AE  P +  +A+  A  T  A+G   P  TAA
Sbjct: 319 AGGPAG--VSGQPGPGAAAAAPA-PGVKAE-SPKRVVQAAPPAAQTLAASG---PASTAA 371

Query: 396 SEAASSSL------PAVVVETFPATVNGTVEGGSGA 425
           S     ++      PA V    P T  G  +G +GA
Sbjct: 372 SMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGA 407



 Score = 38.1 bits (87), Expect = 0.019
 Identities = 41/145 (28%), Positives = 52/145 (35%), Gaps = 13/145 (8%)

Query: 285 PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATL----PKSPSQPTESPA 340
           P     A G    +PP    AA P       P P     P A      P  P+  T +  
Sbjct: 227 PLPKPAAPGTVIQTPPFVGAAAPPAPAA---PSPPAAPAPAAPAAAPPPPPPAPATLARP 283

Query: 341 GSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEA-SEVAGGTQPAAGAQEPGETAASEA- 398
              P+G P+AA    AV  P+     G A  A A +  AGG    +G   PG  AA+ A 
Sbjct: 284 PGHPAGPPTAAP---AVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAP 340

Query: 399 -ASSSLPAVVVETFPATVNGTVEGG 422
              +  P  VV+  P         G
Sbjct: 341 GVKAESPKRVVQAAPPAAQTLAASG 365



 Score = 35.8 bits (81), Expect = 0.094
 Identities = 40/137 (29%), Positives = 47/137 (34%), Gaps = 20/137 (14%)

Query: 307 TPEIRV-------NH--EPEPAGGATPGATLPKSPSQPTESPAGSLPSGEPSAAEGTFAV 357
           TPE+R        NH     PAG A  G      P+ P E   G+ P   P+      A 
Sbjct: 47  TPEVRAAAAGALGNHVVSGSPAGAAGAG------PAAPAEGAPGAAPEPPPAGR----AR 96

Query: 358 SWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGE-TAASEAASSSLPAVVVETFPATVN 416
                   PGP  P      AG   PAA  + P E +A S A   +  AV     PA   
Sbjct: 97  PGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAG 156

Query: 417 GTVEGGSGAGRLDLPPG 433
                G  A      PG
Sbjct: 157 PAKPAGPAALAARAGPG 173


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 48/139 (34%), Positives = 66/139 (47%), Gaps = 12/139 (8%)

Query: 289  APAKGNKSPSPPDGSPAA---TPEIRVNHE---PEPAGGATPGATLPKSPSQPTESPAGS 342
            +PA    +P  P  SPAA   TPE   +     P P   A+P A +P +P +P   PA +
Sbjct: 1093 SPAAAVPTPEEPT-SPAAAVPTPEEPASPAAAVPTPEEPASPAAAVP-TPEEPA-FPAPA 1149

Query: 343  LPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSS 402
            +P+ E SA+    AV  P ++A P  A P  A E A      A  +EP   AAS    ++
Sbjct: 1150 VPTPEESAS-AAVAVPTPEESASPAAAVPTPA-ESASFAAVVATLEEPTSPAASVPTPAA 1207

Query: 403  LPAVVVE-TFPATVNGTVE 420
            + A + E T PA    T E
Sbjct: 1208 MVATLEEFTSPAASVPTSE 1226



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 48/179 (26%), Positives = 73/179 (40%), Gaps = 16/179 (8%)

Query: 244  SIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGS 303
            +++  EE      + + Q     + G   +  +   TV     D  P +G  +P+    +
Sbjct: 925  AVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTP-EGPVTPATTVHA 983

Query: 304  PAA--TPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSLPSGEPSAAEGTFAVSWPS 361
            P    T  +RV+   EP   A+P A +P +P +PT SPA ++P+ E   +    AV  P 
Sbjct: 984  PEEPDTAAVRVSTPEEP---ASPAAAVP-TPEEPT-SPAAAVPTPEEPTSPAA-AVPPPE 1037

Query: 362  QTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVE 420
            +   P  A P         T PAA    P E  +  AA   +P     T PA    T E
Sbjct: 1038 EPTSPAAAVPTPEEP----TSPAAAVPTPEEPTSPAAA---VPTPEEPTSPAAAVPTPE 1089



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 52/164 (31%), Positives = 71/164 (43%), Gaps = 36/164 (21%)

Query: 289  APAKGNKSPSPPDGSPAA---TPEIRVNHE---PEPAGGATPGATLPKSPSQPTESPAGS 342
            +PA    +P  P  SPAA   TPE   +     P P    +P A +P +P +PT SPA +
Sbjct: 1054 SPAAAVPTPEEPT-SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP-TPEEPT-SPAAA 1110

Query: 343  LPSGE----PSAAEGT--------FAVSWPSQTAEPGPAQPAEASEVAG---------GT 381
            +P+ E    P+AA  T         AV  P + A P PA P      +            
Sbjct: 1111 VPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESA 1170

Query: 382  QPAAGAQEPGETAASEAASSSL-----PAVVVETFPATVNGTVE 420
             PAA    P E+A+  A  ++L     PA  V T PA +  T+E
Sbjct: 1171 SPAAAVPTPAESASFAAVVATLEEPTSPAASVPT-PAAMVATLE 1213



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 41/154 (26%), Positives = 56/154 (36%), Gaps = 14/154 (9%)

Query: 278  TFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ--P 335
            T    A P+   P     +  PP+   +    +    EP     A P    P SP+   P
Sbjct: 1014 TSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP 1073

Query: 336  T----ESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPG 391
            T     SPA ++P+ E   +    AV  P +   P  A P      +    PAA    P 
Sbjct: 1074 TPEEPTSPAAAVPTPEEPTSPAA-AVPTPEEPTSPAAAVPTPEEPAS----PAAAVPTPE 1128

Query: 392  ETAASEAASSSLPAVVVETFPATVNGTVEGGSGA 425
            E A+  AA   +P      FPA    T E  + A
Sbjct: 1129 EPASPAAA---VPTPEEPAFPAPAVPTPEESASA 1159



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 42/133 (31%), Positives = 56/133 (42%), Gaps = 22/133 (16%)

Query: 303  SPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSLPSGEPSAAEGTFAVSWPSQ 362
            SPAA+  +  + EP     A        +P +PT SPA ++P+ E   +    AV  P +
Sbjct: 1217 SPAAS--VPTSEEPASLAAAV------SNPEEPT-SPAAAVPTLEEPTSSAA-AVLTPEE 1266

Query: 363  TAEPG--------PAQPAEA-SEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPA 413
             + P         PA PA A S +     PAA    P E AA  AAS  +P   V   PA
Sbjct: 1267 LSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTP-EVAAIPAAS--VPTPEVPAIPA 1323

Query: 414  TVNGTVEGGSGAG 426
                 +E  S  G
Sbjct: 1324 AAVPPMEEVSPIG 1336



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 39/150 (26%), Positives = 53/150 (35%), Gaps = 8/150 (5%)

Query: 283  AQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGS 342
            A P+   PA    +   P+      P +    E   A  A P      SP+    +PA S
Sbjct: 1123 AVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAES 1182

Query: 343  LPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSS 402
                  S A     +  P+  A   P   A  + +   T PAA      E  AS AA+ S
Sbjct: 1183 -----ASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASV-PTSEEPASLAAAVS 1236

Query: 403  LPAVVVETFPATVNGTVEGGSGAGRLDLPP 432
             P     T PA    T+E  + +    L P
Sbjct: 1237 NPE--EPTSPAAAVPTLEEPTSSAAAVLTP 1264


>gi|49640014 ubiquitin associated and SH3 domain containing, A short
           form [Homo sapiens]
          Length = 623

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 24/67 (35%), Positives = 35/67 (52%), Gaps = 9/67 (13%)

Query: 438 VQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVF 497
           ++A   Y   + DEL L  GD + V P Q  +E  EGW++G+ +           CRG  
Sbjct: 243 LRALFQYKPQNVDELTLSPGDYIFVDPTQQ-DEASEGWVIGISQR--------TGCRGFL 293

Query: 498 PENFTER 504
           PEN+T+R
Sbjct: 294 PENYTDR 300


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.127    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,786,040
Number of Sequences: 37866
Number of extensions: 1237692
Number of successful extensions: 11742
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 211
Number of HSP's successfully gapped in prelim test: 1282
Number of HSP's that attempted gapping in prelim test: 7547
Number of HSP's gapped (non-prelim): 4440
length of query: 506
length of database: 18,247,518
effective HSP length: 107
effective length of query: 399
effective length of database: 14,195,856
effective search space: 5664146544
effective search space used: 5664146544
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.