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Search of human proteins with 21536398
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21536398 angiopoietin-like 4 protein isoform a precursor
[Homo sapiens]
(406 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21536398 angiopoietin-like 4 protein isoform a precursor [Hom... 838 0.0
gi|89264696 angiopoietin-like 4 protein isoform b precursor [Hom... 738 0.0
gi|7656888 angiopoietin-like 3 precursor [Homo sapiens] 199 3e-51
gi|169646754 angiopoietin 2 isoform c precursor [Homo sapiens] 165 6e-41
gi|169646749 angiopoietin 2 isoform b precursor [Homo sapiens] 165 6e-41
gi|4557315 angiopoietin 2 isoform a precursor [Homo sapiens] 165 6e-41
gi|20532340 angiopoietin 1 [Homo sapiens] 164 1e-40
gi|42544202 fibrinogen-like 1 precursor [Homo sapiens] 162 7e-40
gi|42544200 fibrinogen-like 1 precursor [Homo sapiens] 162 7e-40
gi|42544198 fibrinogen-like 1 precursor [Homo sapiens] 162 7e-40
gi|42544189 fibrinogen-like 1 precursor [Homo sapiens] 162 7e-40
gi|4757752 angiopoietin-like 1 precursor [Homo sapiens] 160 1e-39
gi|7705276 angiopoietin 4 [Homo sapiens] 159 4e-39
gi|6912236 angiopoietin-like 2 precursor [Homo sapiens] 155 5e-38
gi|10863949 angiopoietin-like 7 [Homo sapiens] 152 5e-37
gi|27754776 ficolin 3 isoform 1 precursor [Homo sapiens] 152 7e-37
gi|4503689 fibrinogen, alpha polypeptide isoform alpha-E preprop... 151 1e-36
gi|8051586 ficolin 2 isoform b precursor [Homo sapiens] 149 3e-36
gi|61744445 ficolin 2 isoform a precursor [Homo sapiens] 149 3e-36
gi|29893555 angiopoietin-like 6 [Homo sapiens] 149 3e-36
gi|8051584 ficolin 1 precursor [Homo sapiens] 149 3e-36
gi|70906439 fibrinogen, gamma chain isoform gamma-B precursor [H... 147 1e-35
gi|70906437 fibrinogen, gamma chain isoform gamma-A precursor [H... 147 1e-35
gi|223029463 fibrinogen C domain containing 1 [Homo sapiens] 147 2e-35
gi|223029461 fibrinogen C domain containing 1 [Homo sapiens] 147 2e-35
gi|27754778 ficolin 3 isoform 2 precursor [Homo sapiens] 147 2e-35
gi|23111005 microfibrillar-associated protein 4 [Homo sapiens] 142 7e-34
gi|70906435 fibrinogen, beta chain preproprotein [Homo sapiens] 134 2e-31
gi|5730075 fibrinogen-like 2 precursor [Homo sapiens] 132 4e-31
gi|157384973 tenascin R [Homo sapiens] 127 2e-29
>gi|21536398 angiopoietin-like 4 protein isoform a precursor [Homo
sapiens]
Length = 406
Score = 838 bits (2164), Expect = 0.0
Identities = 406/406 (100%), Positives = 406/406 (100%)
Query: 1 MSGAPTAGAALMLCAATAVLLSAQGGPVQSKSPRFASWDEMNVLAHGLLQLGQGLREHAE 60
MSGAPTAGAALMLCAATAVLLSAQGGPVQSKSPRFASWDEMNVLAHGLLQLGQGLREHAE
Sbjct: 1 MSGAPTAGAALMLCAATAVLLSAQGGPVQSKSPRFASWDEMNVLAHGLLQLGQGLREHAE 60
Query: 61 RTRSQLSALERRLSACGSACQGTEGSTDLPLAPESRVDPEVLHSLQTQLKAQNSRIQQLF 120
RTRSQLSALERRLSACGSACQGTEGSTDLPLAPESRVDPEVLHSLQTQLKAQNSRIQQLF
Sbjct: 61 RTRSQLSALERRLSACGSACQGTEGSTDLPLAPESRVDPEVLHSLQTQLKAQNSRIQQLF 120
Query: 121 HKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARRKRLPEMAQPVDPAHNVSR 180
HKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARRKRLPEMAQPVDPAHNVSR
Sbjct: 121 HKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARRKRLPEMAQPVDPAHNVSR 180
Query: 181 LHRLPRDCQELFQVGERQSGLFEIQPQGSPPFLVNCKMTSDGGWTVIQRRHDGSVDFNRP 240
LHRLPRDCQELFQVGERQSGLFEIQPQGSPPFLVNCKMTSDGGWTVIQRRHDGSVDFNRP
Sbjct: 181 LHRLPRDCQELFQVGERQSGLFEIQPQGSPPFLVNCKMTSDGGWTVIQRRHDGSVDFNRP 240
Query: 241 WEAYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQFSVHLGGEDTAY 300
WEAYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQFSVHLGGEDTAY
Sbjct: 241 WEAYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQFSVHLGGEDTAY 300
Query: 301 SLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSHSNLN 360
SLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSHSNLN
Sbjct: 301 SLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSHSNLN 360
Query: 361 GQYFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQPMAAEAAS 406
GQYFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQPMAAEAAS
Sbjct: 361 GQYFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQPMAAEAAS 406
>gi|89264696 angiopoietin-like 4 protein isoform b precursor [Homo
sapiens]
Length = 368
Score = 738 bits (1905), Expect = 0.0
Identities = 367/406 (90%), Positives = 367/406 (90%), Gaps = 38/406 (9%)
Query: 1 MSGAPTAGAALMLCAATAVLLSAQGGPVQSKSPRFASWDEMNVLAHGLLQLGQGLREHAE 60
MSGAPTAGAALMLCAATAVLLSAQGGPVQSKSPRFASWDEMNVLAHGLLQLGQGLREHAE
Sbjct: 1 MSGAPTAGAALMLCAATAVLLSAQGGPVQSKSPRFASWDEMNVLAHGLLQLGQGLREHAE 60
Query: 61 RTRSQLSALERRLSACGSACQGTEGSTDLPLAPESRVDPEVLHSLQTQLKAQNSRIQQLF 120
RTRSQLSALERRLSACGSACQGTEGSTDLPLAPESRVDPEVLHSLQTQLKAQNSRIQQLF
Sbjct: 61 RTRSQLSALERRLSACGSACQGTEGSTDLPLAPESRVDPEVLHSLQTQLKAQNSRIQQLF 120
Query: 121 HKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARRKRLPEMAQPVDPAHNVSR 180
HKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARRKRLPEMAQPVDPAHNVSR
Sbjct: 121 HKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARRKRLPEMAQPVDPAHNVSR 180
Query: 181 LHRLPRDCQELFQVGERQSGLFEIQPQGSPPFLVNCKMTSDGGWTVIQRRHDGSVDFNRP 240
LH GGWTVIQRRHDGSVDFNRP
Sbjct: 181 LHH--------------------------------------GGWTVIQRRHDGSVDFNRP 202
Query: 241 WEAYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQFSVHLGGEDTAY 300
WEAYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQFSVHLGGEDTAY
Sbjct: 203 WEAYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQFSVHLGGEDTAY 262
Query: 301 SLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSHSNLN 360
SLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSHSNLN
Sbjct: 263 SLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSHSNLN 322
Query: 361 GQYFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQPMAAEAAS 406
GQYFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQPMAAEAAS
Sbjct: 323 GQYFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQPMAAEAAS 368
>gi|7656888 angiopoietin-like 3 precursor [Homo sapiens]
Length = 460
Score = 199 bits (507), Expect = 3e-51
Identities = 130/430 (30%), Positives = 208/430 (48%), Gaps = 66/430 (15%)
Query: 34 RFASWDEMNVLAHGLLQLGQGLREHAERTRSQLSALERRL-----SACGSACQGTE---- 84
RFA D++ +LA+GLLQLG GL++ +T+ Q++ + ++L S + Q +E
Sbjct: 36 RFAMLDDVKILANGLLQLGHGLKDFVHKTKGQINDIFQKLNIFDQSFYDLSLQTSEIKEE 95
Query: 85 --------------------GSTDLPLAPESRVDPEVLHSLQTQLKAQNSRIQQLFHKVA 124
S +L ES ++ ++L LQ ++K ++ L
Sbjct: 96 EKELRRTTYKLQVKNEEVKNMSLELNSKLESLLEEKIL--LQQKVKYLEEQLTNLIQNQP 153
Query: 125 QQQRHLEKQHLR-------------IQHLQSQFGLLDHKHLD-HEVAKPARRKRLPE--- 167
+ H E L+ +Q ++ Q+ L+ +H E+ RR + E
Sbjct: 154 ETPEHPEVTSLKTFVEKQDNSIKDLLQTVEDQYKQLNQQHSQIKEIENQLRRTSIQEPTE 213
Query: 168 -------MAQPVDPAHNVSRLHR-----LPRDCQELFQVGERQSGLFEIQPQGSPPFLVN 215
A P ++ + +P +C ++ GE SG++ I+P S F V
Sbjct: 214 ISLSSKPRAPRTTPFLQLNEIRNVKHDGIPAECTTIYNRGEHTSGMYAIRPSNSQVFHVY 273
Query: 216 CKMTSDGGWTVIQRRHDGSVDFNRPWEAYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAV 275
C + S WT+IQ R DGS +FN WE YK GFG GEFWLGLEK++SI N L +
Sbjct: 274 CDVISGSPWTLIQHRIDGSQNFNETWENYKYGFGRLDGEFWLGLEKIYSIVKQSNYVLRI 333
Query: 276 QLRDWDGNAELLQFSVHLGGEDTAYSLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDL 335
+L DW N +++S +LG +T Y+L L A + G + P + FSTW DH
Sbjct: 334 ELEDWKDNKHYIEYSFYLGNHETNYTLHLVA-ITGNV--PNAIPENKDLVFSTW--DHKA 388
Query: 336 RRDKNCAKSLSGGWWF-GTCSHSNLNGQYFRSIPQQRQKLKKGIFWKTWRGRYYPLQATT 394
+ NC + SGGWW+ C +NLNG+Y + + + + ++G+ WK+ GR Y +++T
Sbjct: 389 KGHFNCPEGYSGGWWWHDECGENNLNGKYNKPRAKSKPERRRGLSWKSQNGRLYSIKSTK 448
Query: 395 MLIQPMAAEA 404
MLI P +E+
Sbjct: 449 MLIHPTDSES 458
>gi|169646754 angiopoietin 2 isoform c precursor [Homo sapiens]
Length = 444
Score = 165 bits (418), Expect = 6e-41
Identities = 93/221 (42%), Positives = 127/221 (57%), Gaps = 16/221 (7%)
Query: 186 RDCQELFQVGERQSGLFEIQ-PQGSPPFLVNCKMTSDGG-WTVIQRRHDGSVDFNRPWEA 243
RDC E+F+ G +G++ + P + C M + GG WT+IQRR DGSVDF R W+
Sbjct: 230 RDCAEVFKSGHTTNGIYTLTFPNSTEEIKAYCDMEAGGGGWTIIQRREDGSVDFQRTWKE 289
Query: 244 YKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGN-AELLQFSVHLGGEDTAYSL 302
YK GFG+P GE+WLG E V +T + L + L+DW+GN A L +L E+ Y +
Sbjct: 290 YKVGFGNPSGEYWLGNEFVSQLTNQQRYVLKIHLKDWEGNEAYSLYEHFYLSSEELNYRI 349
Query: 303 QL--TAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSHSNLN 360
L AG++ + + P + FST D D+D K C++ L+GGWWF C SNLN
Sbjct: 350 HLKGLTGTAGKISSISQPGN----DFSTKDGDNDKCICK-CSQMLTGGWWFDACGPSNLN 404
Query: 361 GQYFRSIPQQRQKLKK--GIFWKTWRGRYYPLQATTMLIQP 399
G Y+ QRQ K GI W W+G Y L+ATTM+I+P
Sbjct: 405 GMYY----PQRQNTNKFNGIKWYYWKGSGYSLKATTMMIRP 441
>gi|169646749 angiopoietin 2 isoform b precursor [Homo sapiens]
Length = 495
Score = 165 bits (418), Expect = 6e-41
Identities = 93/221 (42%), Positives = 127/221 (57%), Gaps = 16/221 (7%)
Query: 186 RDCQELFQVGERQSGLFEIQ-PQGSPPFLVNCKMTSDGG-WTVIQRRHDGSVDFNRPWEA 243
RDC E+F+ G +G++ + P + C M + GG WT+IQRR DGSVDF R W+
Sbjct: 281 RDCAEVFKSGHTTNGIYTLTFPNSTEEIKAYCDMEAGGGGWTIIQRREDGSVDFQRTWKE 340
Query: 244 YKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGN-AELLQFSVHLGGEDTAYSL 302
YK GFG+P GE+WLG E V +T + L + L+DW+GN A L +L E+ Y +
Sbjct: 341 YKVGFGNPSGEYWLGNEFVSQLTNQQRYVLKIHLKDWEGNEAYSLYEHFYLSSEELNYRI 400
Query: 303 QL--TAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSHSNLN 360
L AG++ + + P + FST D D+D K C++ L+GGWWF C SNLN
Sbjct: 401 HLKGLTGTAGKISSISQPGN----DFSTKDGDNDKCICK-CSQMLTGGWWFDACGPSNLN 455
Query: 361 GQYFRSIPQQRQKLKK--GIFWKTWRGRYYPLQATTMLIQP 399
G Y+ QRQ K GI W W+G Y L+ATTM+I+P
Sbjct: 456 GMYY----PQRQNTNKFNGIKWYYWKGSGYSLKATTMMIRP 492
>gi|4557315 angiopoietin 2 isoform a precursor [Homo sapiens]
Length = 496
Score = 165 bits (418), Expect = 6e-41
Identities = 93/221 (42%), Positives = 127/221 (57%), Gaps = 16/221 (7%)
Query: 186 RDCQELFQVGERQSGLFEIQ-PQGSPPFLVNCKMTSDGG-WTVIQRRHDGSVDFNRPWEA 243
RDC E+F+ G +G++ + P + C M + GG WT+IQRR DGSVDF R W+
Sbjct: 282 RDCAEVFKSGHTTNGIYTLTFPNSTEEIKAYCDMEAGGGGWTIIQRREDGSVDFQRTWKE 341
Query: 244 YKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGN-AELLQFSVHLGGEDTAYSL 302
YK GFG+P GE+WLG E V +T + L + L+DW+GN A L +L E+ Y +
Sbjct: 342 YKVGFGNPSGEYWLGNEFVSQLTNQQRYVLKIHLKDWEGNEAYSLYEHFYLSSEELNYRI 401
Query: 303 QL--TAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSHSNLN 360
L AG++ + + P + FST D D+D K C++ L+GGWWF C SNLN
Sbjct: 402 HLKGLTGTAGKISSISQPGN----DFSTKDGDNDKCICK-CSQMLTGGWWFDACGPSNLN 456
Query: 361 GQYFRSIPQQRQKLKK--GIFWKTWRGRYYPLQATTMLIQP 399
G Y+ QRQ K GI W W+G Y L+ATTM+I+P
Sbjct: 457 GMYY----PQRQNTNKFNGIKWYYWKGSGYSLKATTMMIRP 493
>gi|20532340 angiopoietin 1 [Homo sapiens]
Length = 498
Score = 164 bits (416), Expect = 1e-40
Identities = 121/376 (32%), Positives = 180/376 (47%), Gaps = 51/376 (13%)
Query: 69 LERRLSACGSACQGTEGSTDLP---LAPESRVDPEVLHSLQTQLKAQNSRIQQ------- 118
LE S + T TD+ L SR++ ++L + + K + +QQ
Sbjct: 128 LEIGTSLLSQTAEQTRKLTDVETQVLNQTSRLEIQLLENSLSTYKLEKQLLQQTNEILKI 187
Query: 119 ------LFHKVAQQQ-RHLEKQHLRIQHLQSQFGLLDHK-HLDHEVAKPARRKRL----- 165
L HK+ + + +H E+ + ++ GL+ + ++ E+ K R
Sbjct: 188 HEKNSLLEHKILEMEGKHKEELDTLKEEKENLQGLVTRQTYIIQELEKQLNRATTNNSVL 247
Query: 166 -PEMAQPVDPAHNVSRL---------------HRLPRDCQELFQVGERQSGLFEIQPQGS 209
+ + +D HN+ L + RDC +++Q G +SG++ I
Sbjct: 248 QKQQLELMDTVHNLVNLCTKEGVLLKGGKREEEKPFRDCADVYQAGFNKSGIYTIYINNM 307
Query: 210 P-PFLVNCKM-TSDGGWTVIQRRHDGSVDFNRPWEAYKAGFGDPHGEFWLGLEKVHSITG 267
P P V C M + GGWTVIQ R DGS+DF R W+ YK GFG+P GE+WLG E + +IT
Sbjct: 308 PEPKKVFCNMDVNGGGWTVIQHREDGSLDFQRGWKEYKMGFGNPSGEYWLGNEFIFAITS 367
Query: 268 DRNSRLAVQLRDWDGNAELLQFS-VHLGGEDTAYSLQLTAPVAGQLGATTVPPSGL--SV 324
R L ++L DW+GN Q+ H+G E Y L L G G S +
Sbjct: 368 QRQYMLRIELMDWEGNRAYSQYDRFHIGNEKQNYRLYL----KGHTGTAGKQSSLILHGA 423
Query: 325 PFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSHSNLNGQYFRSIPQQRQKLKKGIFWKTWR 384
FST D D+D K CA L+GGWWF C SNLNG ++ + Q KL GI W ++
Sbjct: 424 DFSTKDADNDNCMCK-CALMLTGGWWFDACGPSNLNGMFY-TAGQNHGKL-NGIKWHYFK 480
Query: 385 GRYYPLQATTMLIQPM 400
G Y L++TTM+I+P+
Sbjct: 481 GPSYSLRSTTMMIRPL 496
>gi|42544202 fibrinogen-like 1 precursor [Homo sapiens]
Length = 312
Score = 162 bits (409), Expect = 7e-40
Identities = 90/226 (39%), Positives = 124/226 (54%), Gaps = 16/226 (7%)
Query: 187 DCQELFQVGERQSGLFEIQPQGSPP-FLVNCKMTSDGGWTVIQRRHDGSVDFNRPWEAYK 245
DC E+F G + SG ++I+P SP F V C M+ GGWTVIQRR DGS +FNR W+ Y+
Sbjct: 82 DCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDMSDGGGWTVIQRRSDGSENFNRGWKDYE 141
Query: 246 AGFGD---PHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQF-SVHLGGEDTAYS 301
GFG+ HGE+WLG + +H +T + L + L D++ N+ Q+ + +G E Y
Sbjct: 142 NGFGNFVQKHGEYWLGNKNLHFLTTQEDYTLKIDLADFEKNSRYAQYKNFKVGDEKNFYE 201
Query: 302 LQL--TAPVAGQLGATTVPP------SGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGT 353
L + + AG A P S + FSTWD+DHD + NCA+ GWWF
Sbjct: 202 LNIGEYSGTAGDSLAGNFHPEVQWWASHQRMKFSTWDRDHD-NYEGNCAEEDQSGWWFNR 260
Query: 354 CSHSNLNGQYFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQP 399
C +NLNG Y+ K GI W TW G +Y L++ M I+P
Sbjct: 261 CHSANLNGVYYSG--PYTAKTDNGIVWYTWHGWWYSLKSVVMKIRP 304
>gi|42544200 fibrinogen-like 1 precursor [Homo sapiens]
Length = 312
Score = 162 bits (409), Expect = 7e-40
Identities = 90/226 (39%), Positives = 124/226 (54%), Gaps = 16/226 (7%)
Query: 187 DCQELFQVGERQSGLFEIQPQGSPP-FLVNCKMTSDGGWTVIQRRHDGSVDFNRPWEAYK 245
DC E+F G + SG ++I+P SP F V C M+ GGWTVIQRR DGS +FNR W+ Y+
Sbjct: 82 DCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDMSDGGGWTVIQRRSDGSENFNRGWKDYE 141
Query: 246 AGFGD---PHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQF-SVHLGGEDTAYS 301
GFG+ HGE+WLG + +H +T + L + L D++ N+ Q+ + +G E Y
Sbjct: 142 NGFGNFVQKHGEYWLGNKNLHFLTTQEDYTLKIDLADFEKNSRYAQYKNFKVGDEKNFYE 201
Query: 302 LQL--TAPVAGQLGATTVPP------SGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGT 353
L + + AG A P S + FSTWD+DHD + NCA+ GWWF
Sbjct: 202 LNIGEYSGTAGDSLAGNFHPEVQWWASHQRMKFSTWDRDHD-NYEGNCAEEDQSGWWFNR 260
Query: 354 CSHSNLNGQYFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQP 399
C +NLNG Y+ K GI W TW G +Y L++ M I+P
Sbjct: 261 CHSANLNGVYYSG--PYTAKTDNGIVWYTWHGWWYSLKSVVMKIRP 304
>gi|42544198 fibrinogen-like 1 precursor [Homo sapiens]
Length = 312
Score = 162 bits (409), Expect = 7e-40
Identities = 90/226 (39%), Positives = 124/226 (54%), Gaps = 16/226 (7%)
Query: 187 DCQELFQVGERQSGLFEIQPQGSPP-FLVNCKMTSDGGWTVIQRRHDGSVDFNRPWEAYK 245
DC E+F G + SG ++I+P SP F V C M+ GGWTVIQRR DGS +FNR W+ Y+
Sbjct: 82 DCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDMSDGGGWTVIQRRSDGSENFNRGWKDYE 141
Query: 246 AGFGD---PHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQF-SVHLGGEDTAYS 301
GFG+ HGE+WLG + +H +T + L + L D++ N+ Q+ + +G E Y
Sbjct: 142 NGFGNFVQKHGEYWLGNKNLHFLTTQEDYTLKIDLADFEKNSRYAQYKNFKVGDEKNFYE 201
Query: 302 LQL--TAPVAGQLGATTVPP------SGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGT 353
L + + AG A P S + FSTWD+DHD + NCA+ GWWF
Sbjct: 202 LNIGEYSGTAGDSLAGNFHPEVQWWASHQRMKFSTWDRDHD-NYEGNCAEEDQSGWWFNR 260
Query: 354 CSHSNLNGQYFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQP 399
C +NLNG Y+ K GI W TW G +Y L++ M I+P
Sbjct: 261 CHSANLNGVYYSG--PYTAKTDNGIVWYTWHGWWYSLKSVVMKIRP 304
>gi|42544189 fibrinogen-like 1 precursor [Homo sapiens]
Length = 312
Score = 162 bits (409), Expect = 7e-40
Identities = 90/226 (39%), Positives = 124/226 (54%), Gaps = 16/226 (7%)
Query: 187 DCQELFQVGERQSGLFEIQPQGSPP-FLVNCKMTSDGGWTVIQRRHDGSVDFNRPWEAYK 245
DC E+F G + SG ++I+P SP F V C M+ GGWTVIQRR DGS +FNR W+ Y+
Sbjct: 82 DCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDMSDGGGWTVIQRRSDGSENFNRGWKDYE 141
Query: 246 AGFGD---PHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQF-SVHLGGEDTAYS 301
GFG+ HGE+WLG + +H +T + L + L D++ N+ Q+ + +G E Y
Sbjct: 142 NGFGNFVQKHGEYWLGNKNLHFLTTQEDYTLKIDLADFEKNSRYAQYKNFKVGDEKNFYE 201
Query: 302 LQL--TAPVAGQLGATTVPP------SGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGT 353
L + + AG A P S + FSTWD+DHD + NCA+ GWWF
Sbjct: 202 LNIGEYSGTAGDSLAGNFHPEVQWWASHQRMKFSTWDRDHD-NYEGNCAEEDQSGWWFNR 260
Query: 354 CSHSNLNGQYFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQP 399
C +NLNG Y+ K GI W TW G +Y L++ M I+P
Sbjct: 261 CHSANLNGVYYSG--PYTAKTDNGIVWYTWHGWWYSLKSVVMKIRP 304
>gi|4757752 angiopoietin-like 1 precursor [Homo sapiens]
Length = 491
Score = 160 bits (406), Expect = 1e-39
Identities = 88/218 (40%), Positives = 128/218 (58%), Gaps = 8/218 (3%)
Query: 186 RDCQELFQVGERQSGLFEIQPQGSP-PFLVNCKMTSD-GGWTVIQRRHDGSVDFNRPWEA 243
+DCQ+ + G SG++ I+P+ S P + C+ + D GGWTVIQ+R DGSV+F R WE
Sbjct: 278 KDCQQAKEAGHSVSGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWEN 337
Query: 244 YKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQF-SVHLGGEDTAYSL 302
YK GFG+ GE+WLGLE ++ ++ N +L ++L DW ++ S L E Y L
Sbjct: 338 YKKGFGNIDGEYWLGLENIYMLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRL 397
Query: 303 QLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSHSNLNGQ 362
+L G G + + +G F+T D+D D+ NCA GGWW+ C+HSNLNG
Sbjct: 398 RL-GTYQGNAGDSMMWHNGKQ--FTTLDRDKDMYAG-NCAHFHKGGWWYNACAHSNLNGV 453
Query: 363 YFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQPM 400
++R R K + GIFW +RG Y L+A M+I+P+
Sbjct: 454 WYRG-GHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPI 490
>gi|7705276 angiopoietin 4 [Homo sapiens]
Length = 503
Score = 159 bits (402), Expect = 4e-39
Identities = 118/350 (33%), Positives = 179/350 (51%), Gaps = 38/350 (10%)
Query: 56 REHAERTRSQLSALERRLSACGSACQGTEGSTDLPLAPESRVDPEVLHSLQTQLKAQNSR 115
R+ ++ + Q SALE+RL A E++ E+ L + K N+
Sbjct: 185 RQKLQQLQGQNSALEKRLQAL-----------------ETKQQEELASILSKKAKLLNTL 227
Query: 116 IQQLFHKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARRKRLPEMAQPVDPA 175
+Q + ++E+ ++H S L D +H ++ R + E A PA
Sbjct: 228 SRQ-----SAALTNIERGLRGVRHNSSL--LQDQQHSLRQLLVLLRHL-VQERANASAPA 279
Query: 176 HNVSRLHRLPRDCQELFQVGERQSGLFEIQ-PQGSPPFLVNCKMTSDGG-WTVIQRRHDG 233
++ ++ +DC E+ + G SG++ IQ + P V C + S GG WT+IQRR +G
Sbjct: 280 FIMAG-EQVFQDCAEIQRSGASASGVYTIQVSNATKPRKVFCDLQSSGGRWTLIQRRENG 338
Query: 234 SVDFNRPWEAYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQFS-VH 292
+V+F R W+ YK GFGDP GE WLG E VH +T L V+L+DW+G+ Q+ H
Sbjct: 339 TVNFQRNWKDYKQGFGDPAGEHWLGNEVVHQLTRRAAYSLRVELQDWEGHEAYAQYEHFH 398
Query: 293 LGGEDTAYSLQLTAPVAGQLGATTVPPSGL--SVPFSTWDQDHDLRRDKNCAKSLSGGWW 350
LG E+ Y L V G G+ S + + FST D D+D K CA+ +SGGWW
Sbjct: 399 LGSENQLYRLS----VVGYSGSAGRQSSLVLQNTSFSTLDSDNDHCLCK-CAQVMSGGWW 453
Query: 351 FGTCSHSNLNGQYFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQPM 400
F C SNLNG Y+ + P + K+ GI W ++G Y L+A+ M+I+P+
Sbjct: 454 FDACGLSNLNGVYYHA-PDNKYKM-DGIRWHYFKGPSYSLRASRMMIRPL 501
>gi|6912236 angiopoietin-like 2 precursor [Homo sapiens]
Length = 493
Score = 155 bits (393), Expect = 5e-38
Identities = 85/217 (39%), Positives = 122/217 (56%), Gaps = 8/217 (3%)
Query: 186 RDCQELFQVGERQSGLFEIQPQGSPPFL-VNCKMTSD-GGWTVIQRRHDGSVDFNRPWEA 243
RDC + + G S ++ ++P+ + + V C D GGWTVIQRR DGSV+F R WE
Sbjct: 276 RDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWET 335
Query: 244 YKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQF-SVHLGGEDTAYSL 302
YK GFG+ GE+WLGLE ++ +T N +L V + DW G ++ S L E Y L
Sbjct: 336 YKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRLEPESEYYKL 395
Query: 303 QLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSHSNLNGQ 362
+L G G + +G F+T D+DHD+ NCA GGWW+ C+HSNLNG
Sbjct: 396 RL-GRYHGNAGDSFTWHNGKQ--FTTLDRDHDVYTG-NCAHYQKGGWWYNACAHSNLNGV 451
Query: 363 YFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQP 399
++R R + + G++W +RG Y L+ M+I+P
Sbjct: 452 WYRG-GHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRP 487
>gi|10863949 angiopoietin-like 7 [Homo sapiens]
Length = 346
Score = 152 bits (384), Expect = 5e-37
Identities = 103/299 (34%), Positives = 154/299 (51%), Gaps = 15/299 (5%)
Query: 108 QLKAQNSRIQQLFHKV-AQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARRKRLP 166
+LKAQ + + L ++ +Q+R +++ L+S ++ + D E ++
Sbjct: 51 ELKAQVANLSSLLSELNKKQERDWVSVVMQVMELESNSKRMESRLTDAESKYSEMNNQID 110
Query: 167 EMAQPVDPAHNVSRLHR-LPRDCQELFQVGERQSGLFEIQPQ---GSPPFLVNCKM-TSD 221
M + A V++ DC L+Q R SG++++ P GSP V C M TS
Sbjct: 111 IMQ--LQAAQTVTQTSADAIYDCSSLYQKNYRISGVYKLPPDDFLGSPELEVFCDMETSG 168
Query: 222 GGWTVIQRRHDGSVDFNRPWEAYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWD 281
GGWT+IQRR G V F R W+ YK GFG G+FWLG E +H ++ + +RL V++ DW+
Sbjct: 169 GGWTIIQRRKSGLVSFYRDWKQYKQGFGSIRGDFWLGNEHIHRLS-RQPTRLRVEMEDWE 227
Query: 282 GNAELLQFS-VHLGGEDTAYSLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKN 340
GN ++S LG E +Y L L G +G + + FST D+D+D DK
Sbjct: 228 GNLRYAEYSHFVLGNELNSYRLFL-GNYTGNVGNDALQYHN-NTAFSTKDKDNDNCLDK- 284
Query: 341 CAKSLSGGWWFGTCSHSNLNGQYFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQP 399
CA+ GG+W+ C+ SNLNG Y+R + K GI W W G Y L+ M I+P
Sbjct: 285 CAQLRKGGYWYNCCTDSNLNGVYYRL--GEHNKHLDGITWYGWHGSTYSLKRVEMKIRP 341
>gi|27754776 ficolin 3 isoform 1 precursor [Homo sapiens]
Length = 299
Score = 152 bits (383), Expect = 7e-37
Identities = 92/242 (38%), Positives = 125/242 (51%), Gaps = 9/242 (3%)
Query: 159 PARRKRLPEMAQPVDPAHNVSRLHRLPRDCQELFQVGERQSGLFEIQPQGSPPFLVNCKM 218
P ++ +P DP N+ R PR+C+EL G SG + + V C M
Sbjct: 65 PGPPGKMGPKGEPGDPV-NLLRCQEGPRNCRELLSQGATLSGWYHLCLPEGRALPVFCDM 123
Query: 219 -TSDGGWTVIQRRHDGSVDFNRPWEAYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQL 277
T GGW V QRR DGSVDF R W +Y+AGFG+ EFWLG E +H +T N L V+L
Sbjct: 124 DTEGGGWLVFQRRQDGSVDFFRSWSSYRAGFGNQESEFWLGNENLHQLTLQGNWELRVEL 183
Query: 278 RDWDGNAELLQFSV-HLGGEDTAYSLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLR 336
D++GN ++ L GE Y L L G G + SG PF+T+D DHD
Sbjct: 184 EDFNGNRTFAHYATFRLLGEVDHYQLALGKFSEGTAGDSLSLHSGR--PFTTYDADHD-S 240
Query: 337 RDKNCAKSLSGGWWFGTCSHSNLNGQYFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTML 396
+ NCA + G WW+ +C SNLNG+Y S + K GI W + RG +P + M+
Sbjct: 241 SNSNCAVIVHGAWWYASCYRSNLNGRYAVS---EAAAHKYGIDWASGRGVGHPYRRVRMM 297
Query: 397 IQ 398
++
Sbjct: 298 LR 299
>gi|4503689 fibrinogen, alpha polypeptide isoform alpha-E
preproprotein [Homo sapiens]
Length = 866
Score = 151 bits (381), Expect = 1e-36
Identities = 93/252 (36%), Positives = 138/252 (54%), Gaps = 26/252 (10%)
Query: 176 HNVSRLH---RLPRDCQELFQV--GERQSGLFEIQ-PQGSPPFLVNCKM-TSDGGWTVIQ 228
H+ R H R RDC ++ Q QSG+F I+ P S F V C TS GGW +IQ
Sbjct: 617 HSTKRGHAKSRPVRDCDDVLQTHPSGTQSGIFNIKLPGSSKIFSVYCDQETSLGGWLLIQ 676
Query: 229 RRHDGSVDFNRPWEAYKAGFG----DPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNA 284
+R DGS++FNR W+ YK GFG + GEFWLG + +H +T R S L V+L DW GN
Sbjct: 677 QRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLT-QRGSVLRVELEDWAGNE 735
Query: 285 ELLQFSVHLGGEDTAYSLQLT--------APVAGQLGATTVPPSGLSVPFSTWDQDHDLR 336
++ +G E Y+LQ++ A + G + S ++ FST+D+D D +
Sbjct: 736 AYAEYHFRVGSEAEGYALQVSSYEGTAGDALIEGSVEEGAEYTSHNNMQFSTFDRDAD-Q 794
Query: 337 RDKNCAKSLSGGWWFGTCSHSNLNGQYFRS---IPQQRQ--KLKKGIFWKTWRGRYYPLQ 391
++NCA+ GGWW+ C +NLNG Y+ P+ +++ G+ W ++RG Y L+
Sbjct: 795 WEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRNNSPYEIENGVVWVSFRGADYSLR 854
Query: 392 ATTMLIQPMAAE 403
A M I+P+ +
Sbjct: 855 AVRMKIRPLVTQ 866
>gi|8051586 ficolin 2 isoform b precursor [Homo sapiens]
Length = 275
Score = 149 bits (377), Expect = 3e-36
Identities = 88/217 (40%), Positives = 113/217 (52%), Gaps = 8/217 (3%)
Query: 185 PRDCQELFQVGERQSGLFEIQPQGSPPFLVNCKMTSDGG-WTVIQRRHDGSVDFNRPWEA 243
PR C++L G SG I P V C M +DGG WTV QRR DGSVDF R W
Sbjct: 64 PRTCKDLLDRGHFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWAT 123
Query: 244 YKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQF-SVHLGGEDTAYSL 302
YK GFG GEFWLG + +H++T S L V L D++ N + ++ S + E Y+L
Sbjct: 124 YKQGFGSRLGEFWLGNDNIHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAEKYNL 183
Query: 303 QLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSHSNLNGQ 362
L A V G G + + S FST DQD+DL NCA G WW+ C SNLNG+
Sbjct: 184 VLGAFVEGSAGDSLTFHNNQS--FSTKDQDNDLNTG-NCAVMFQGAWWYKNCHVSNLNGR 240
Query: 363 YFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQP 399
Y R GI WK+ +G Y + + M ++P
Sbjct: 241 YLRG---THGSFANGINWKSGKGYNYSYKVSEMKVRP 274
>gi|61744445 ficolin 2 isoform a precursor [Homo sapiens]
Length = 313
Score = 149 bits (377), Expect = 3e-36
Identities = 88/217 (40%), Positives = 113/217 (52%), Gaps = 8/217 (3%)
Query: 185 PRDCQELFQVGERQSGLFEIQPQGSPPFLVNCKMTSDGG-WTVIQRRHDGSVDFNRPWEA 243
PR C++L G SG I P V C M +DGG WTV QRR DGSVDF R W
Sbjct: 102 PRTCKDLLDRGHFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWAT 161
Query: 244 YKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQF-SVHLGGEDTAYSL 302
YK GFG GEFWLG + +H++T S L V L D++ N + ++ S + E Y+L
Sbjct: 162 YKQGFGSRLGEFWLGNDNIHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAEKYNL 221
Query: 303 QLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSHSNLNGQ 362
L A V G G + + S FST DQD+DL NCA G WW+ C SNLNG+
Sbjct: 222 VLGAFVEGSAGDSLTFHNNQS--FSTKDQDNDLNTG-NCAVMFQGAWWYKNCHVSNLNGR 278
Query: 363 YFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQP 399
Y R GI WK+ +G Y + + M ++P
Sbjct: 279 YLRG---THGSFANGINWKSGKGYNYSYKVSEMKVRP 312
>gi|29893555 angiopoietin-like 6 [Homo sapiens]
Length = 470
Score = 149 bits (377), Expect = 3e-36
Identities = 88/217 (40%), Positives = 117/217 (53%), Gaps = 8/217 (3%)
Query: 186 RDCQELFQVGERQSGLFEIQPQGSPPFLVNCKMTSDGG-WTVIQRRHDGSVDFNRPWEAY 244
+DC E Q G QSG++E++ G V C+ +GG WTVIQRR DGSV+F W+ Y
Sbjct: 258 QDCAEARQAGHEQSGVYELRV-GRHVVSVWCEQQLEGGGWTVIQRRQDGSVNFFTTWQHY 316
Query: 245 KAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQF-SVHLGGEDTAYSLQ 303
KAGFG P GE+WLGLE V+ +T + L V L DW G + L E Y L+
Sbjct: 317 KAGFGRPDGEYWLGLEPVYQLTSRGDHELLVLLEDWGGRGARAHYDGFSLEPESDHYRLR 376
Query: 304 LTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSHSNLNGQY 363
L G G + + PFST D+D D NCA GGWW+ C+HSNLNG +
Sbjct: 377 L-GQYHGDAGDSLSWHN--DKPFSTVDRDRD-SYSGNCALYQRGGWWYHACAHSNLNGVW 432
Query: 364 FRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQPM 400
R + + G++W +RG Y L+ MLI+P+
Sbjct: 433 HHG-GHYRSRYQDGVYWAEFRGGAYSLRKAAMLIRPL 468
>gi|8051584 ficolin 1 precursor [Homo sapiens]
Length = 326
Score = 149 bits (377), Expect = 3e-36
Identities = 86/217 (39%), Positives = 113/217 (52%), Gaps = 8/217 (3%)
Query: 185 PRDCQELFQVGERQSGLFEIQPQGSPPFLVNCKMTSDGG-WTVIQRRHDGSVDFNRPWEA 243
PR+C++L G SG I P V C M +DGG WTV QRR DGSVDF R W A
Sbjct: 115 PRNCKDLLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAA 174
Query: 244 YKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQF-SVHLGGEDTAYSL 302
YK GFG GEFWLG + +H++T +S L V L D++GN + ++ S + E Y L
Sbjct: 175 YKQGFGSQLGEFWLGNDNIHALTAQGSSELRVDLVDFEGNHQFAKYKSFKVADEAEKYKL 234
Query: 303 QLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSHSNLNGQ 362
L A V G G + + FST DQD+D+ NCA+ G WW+ C SNLNG
Sbjct: 235 VLGAFVGGSAGNSLTGHNNNF--FSTKDQDNDV-SSSNCAEKFQGAWWYADCHASNLNGL 291
Query: 363 YFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQP 399
Y + GI W +G Y + + M ++P
Sbjct: 292 YLMG---PHESYANGINWSAAKGYKYSYKVSEMKVRP 325
>gi|70906439 fibrinogen, gamma chain isoform gamma-B precursor [Homo
sapiens]
Length = 453
Score = 147 bits (372), Expect = 1e-35
Identities = 116/389 (29%), Positives = 178/389 (45%), Gaps = 55/389 (14%)
Query: 62 TRSQLSALERRLSACGSACQGTEGSTDLPLAPESRVDPEV--LHSLQTQLKAQNSRIQQL 119
TR L+ R GS C T G D +++VD ++ L + Q++ + S ++QL
Sbjct: 30 TRDNCCILDERF---GSYCPTTCGIADFLSTYQTKVDKDLQSLEDILHQVENKTSEVKQL 86
Query: 120 FHKV--------AQQQRHLEKQHLRIQHLQSQFGLLDHKHLDH--------EVAKPARRK 163
+ + + ++ L+ + + + + L H E+ +K
Sbjct: 87 IKAIQLTYNPDESSKPNMIDAATLKSRKMLEEIMKYEASILTHDSSIRYLQEIYNSNNQK 146
Query: 164 --RLPEM-----AQPVDPAHNVSRLHRLP-RDCQELFQVGERQSGLFEIQP-QGSPPFLV 214
L E AQ +P + ++H + +DCQ++ G +QSGL+ I+P + + FLV
Sbjct: 147 IVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLV 206
Query: 215 NCKMTSDG-GWTVIQRRHDGSVDFNRPWEAYKAGFG--DPHG--EFWLGLEKVHSITGDR 269
C++ G GWTV Q+R DGSVDF + W YK GFG P G EFWLG EK+H I+
Sbjct: 207 YCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQS 266
Query: 270 --NSRLAVQLRDWDGNAELLQFSV-HLGGEDTAYSLQLTAPVAGQLG------------A 314
L V+L DW+G +++ +G E Y L G G +
Sbjct: 267 AIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPS 326
Query: 315 TTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSHSNLNGQYFR----SIPQQ 370
S + FSTWD D+D + + NCA+ GWW C +LNG Y++ S
Sbjct: 327 DKFFTSHNGMQFSTWDNDND-KFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKAST 385
Query: 371 RQKLKKGIFWKTWRGRYYPLQATTMLIQP 399
GI W TW+ R+Y ++ TTM I P
Sbjct: 386 PNGYDNGIIWATWKTRWYSMKKTTMKIIP 414
>gi|70906437 fibrinogen, gamma chain isoform gamma-A precursor [Homo
sapiens]
Length = 437
Score = 147 bits (372), Expect = 1e-35
Identities = 116/389 (29%), Positives = 178/389 (45%), Gaps = 55/389 (14%)
Query: 62 TRSQLSALERRLSACGSACQGTEGSTDLPLAPESRVDPEV--LHSLQTQLKAQNSRIQQL 119
TR L+ R GS C T G D +++VD ++ L + Q++ + S ++QL
Sbjct: 30 TRDNCCILDERF---GSYCPTTCGIADFLSTYQTKVDKDLQSLEDILHQVENKTSEVKQL 86
Query: 120 FHKV--------AQQQRHLEKQHLRIQHLQSQFGLLDHKHLDH--------EVAKPARRK 163
+ + + ++ L+ + + + + L H E+ +K
Sbjct: 87 IKAIQLTYNPDESSKPNMIDAATLKSRKMLEEIMKYEASILTHDSSIRYLQEIYNSNNQK 146
Query: 164 --RLPEM-----AQPVDPAHNVSRLHRLP-RDCQELFQVGERQSGLFEIQP-QGSPPFLV 214
L E AQ +P + ++H + +DCQ++ G +QSGL+ I+P + + FLV
Sbjct: 147 IVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLV 206
Query: 215 NCKMTSDG-GWTVIQRRHDGSVDFNRPWEAYKAGFG--DPHG--EFWLGLEKVHSITGDR 269
C++ G GWTV Q+R DGSVDF + W YK GFG P G EFWLG EK+H I+
Sbjct: 207 YCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQS 266
Query: 270 --NSRLAVQLRDWDGNAELLQFSV-HLGGEDTAYSLQLTAPVAGQLG------------A 314
L V+L DW+G +++ +G E Y L G G +
Sbjct: 267 AIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPS 326
Query: 315 TTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSHSNLNGQYFR----SIPQQ 370
S + FSTWD D+D + + NCA+ GWW C +LNG Y++ S
Sbjct: 327 DKFFTSHNGMQFSTWDNDND-KFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKAST 385
Query: 371 RQKLKKGIFWKTWRGRYYPLQATTMLIQP 399
GI W TW+ R+Y ++ TTM I P
Sbjct: 386 PNGYDNGIIWATWKTRWYSMKKTTMKIIP 414
>gi|223029463 fibrinogen C domain containing 1 [Homo sapiens]
Length = 461
Score = 147 bits (370), Expect = 2e-35
Identities = 99/303 (32%), Positives = 147/303 (48%), Gaps = 28/303 (9%)
Query: 109 LKAQNSRIQQLFHKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARR---KRL 165
L A S +L +++ Q H+ HL + S +LD D + +P + +R
Sbjct: 172 LSALQSEQGRLIQLLSESQGHMA--HL----VNSVSDILDALQRDRGLGRPRNKADLQRA 225
Query: 166 PEMAQPVDPAHNVSRLHRLPRDCQELFQVGERQSGLFEIQPQGSPP-FLVNCKMTSDGG- 223
P SR PRDC ++ G++ G++ + P P F V C M +DGG
Sbjct: 226 PARGTRPRGCATGSR----PRDCLDVLLSGQQDDGVYSVFPTHYPAGFQVYCDMRTDGGG 281
Query: 224 WTVIQRRHDGSVDFNRPWEAYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGN 283
WTV QRR DGSV+F R W+AY+ GFG GE WLGL+++H++T L V L D++
Sbjct: 282 WTVFQRREDGSVNFFRGWDAYRDGFGRLTGEHWLGLKRIHALTTQAAYELHVDLEDFENG 341
Query: 284 AELLQFS------VHLGGEDTAYSLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRR 337
++ + E+ Y L + A +G G + + SG+ F+T D+D D
Sbjct: 342 TAYARYGSFGVGLFSVDPEEDGYPLTV-ADYSGTAGDSLLKHSGMR--FTTKDRDSD-HS 397
Query: 338 DKNCAKSLSGGWWFGTCSHSNLNGQYFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLI 397
+ NCA G WW+ C SNLNGQY R G+ W +W G Y L+ + M I
Sbjct: 398 ENNCAAFYRGAWWYRNCHTSNLNGQYLRG---AHASYADGVEWSSWTGWQYSLKFSEMKI 454
Query: 398 QPM 400
+P+
Sbjct: 455 RPV 457
>gi|223029461 fibrinogen C domain containing 1 [Homo sapiens]
Length = 461
Score = 147 bits (370), Expect = 2e-35
Identities = 99/303 (32%), Positives = 147/303 (48%), Gaps = 28/303 (9%)
Query: 109 LKAQNSRIQQLFHKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARR---KRL 165
L A S +L +++ Q H+ HL + S +LD D + +P + +R
Sbjct: 172 LSALQSEQGRLIQLLSESQGHMA--HL----VNSVSDILDALQRDRGLGRPRNKADLQRA 225
Query: 166 PEMAQPVDPAHNVSRLHRLPRDCQELFQVGERQSGLFEIQPQGSPP-FLVNCKMTSDGG- 223
P SR PRDC ++ G++ G++ + P P F V C M +DGG
Sbjct: 226 PARGTRPRGCATGSR----PRDCLDVLLSGQQDDGVYSVFPTHYPAGFQVYCDMRTDGGG 281
Query: 224 WTVIQRRHDGSVDFNRPWEAYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGN 283
WTV QRR DGSV+F R W+AY+ GFG GE WLGL+++H++T L V L D++
Sbjct: 282 WTVFQRREDGSVNFFRGWDAYRDGFGRLTGEHWLGLKRIHALTTQAAYELHVDLEDFENG 341
Query: 284 AELLQFS------VHLGGEDTAYSLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRR 337
++ + E+ Y L + A +G G + + SG+ F+T D+D D
Sbjct: 342 TAYARYGSFGVGLFSVDPEEDGYPLTV-ADYSGTAGDSLLKHSGMR--FTTKDRDSD-HS 397
Query: 338 DKNCAKSLSGGWWFGTCSHSNLNGQYFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLI 397
+ NCA G WW+ C SNLNGQY R G+ W +W G Y L+ + M I
Sbjct: 398 ENNCAAFYRGAWWYRNCHTSNLNGQYLRG---AHASYADGVEWSSWTGWQYSLKFSEMKI 454
Query: 398 QPM 400
+P+
Sbjct: 455 RPV 457
>gi|27754778 ficolin 3 isoform 2 precursor [Homo sapiens]
Length = 288
Score = 147 bits (370), Expect = 2e-35
Identities = 86/216 (39%), Positives = 115/216 (53%), Gaps = 8/216 (3%)
Query: 185 PRDCQELFQVGERQSGLFEIQPQGSPPFLVNCKM-TSDGGWTVIQRRHDGSVDFNRPWEA 243
PR+C+EL G SG + + V C M T GGW V QRR DGSVDF R W +
Sbjct: 79 PRNCRELLSQGATLSGWYHLCLPEGRALPVFCDMDTEGGGWLVFQRRQDGSVDFFRSWSS 138
Query: 244 YKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQFSV-HLGGEDTAYSL 302
Y+AGFG+ EFWLG E +H +T N L V+L D++GN ++ L GE Y L
Sbjct: 139 YRAGFGNQESEFWLGNENLHQLTLQGNWELRVELEDFNGNRTFAHYATFRLLGEVDHYQL 198
Query: 303 QLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSHSNLNGQ 362
L G G + SG PF+T+D DHD + NCA + G WW+ +C SNLNG+
Sbjct: 199 ALGKFSEGTAGDSLSLHSGR--PFTTYDADHD-SSNSNCAVIVHGAWWYASCYRSNLNGR 255
Query: 363 YFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQ 398
Y S + K GI W + RG +P + M+++
Sbjct: 256 YAVS---EAAAHKYGIDWASGRGVGHPYRRVRMMLR 288
>gi|23111005 microfibrillar-associated protein 4 [Homo sapiens]
Length = 255
Score = 142 bits (357), Expect = 7e-34
Identities = 86/222 (38%), Positives = 120/222 (54%), Gaps = 14/222 (6%)
Query: 185 PRDCQELFQVGERQSGLFEIQPQG-SPPFLVNCKMTSDGG-WTVIQRRHDGSVDFNRPWE 242
P DC +++ G + G++ I P G S P V C MT++GG WTV Q+R +GSV F R W
Sbjct: 38 PLDCDDIYAQGYQSDGVYLIYPSGPSVPVPVFCDMTTEGGKWTVFQKRFNGSVSFFRGWN 97
Query: 243 AYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGN---AELLQFSVH---LGGE 296
YK GFG GE+WLGL+ +H +T + L V L D++ N A+ FS+ + E
Sbjct: 98 DYKLGFGRADGEYWLGLQNMHLLTLKQKYELRVDLEDFENNTAYAKYADFSISPNAVSAE 157
Query: 297 DTAYSLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSH 356
+ Y+L + G G + SG FST+D+D DL +NCA SG +WF +C
Sbjct: 158 EDGYTLFVAGFEDGGAGDSLSYHSGQK--FSTFDRDQDL-FVQNCAALSSGAFWFRSCHF 214
Query: 357 SNLNGQYFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQ 398
+NLNG Y + GI W W+G YY L+ T M I+
Sbjct: 215 ANLNGFY---LGGSHLSYANGINWAQWKGFYYSLKRTEMKIR 253
>gi|70906435 fibrinogen, beta chain preproprotein [Homo sapiens]
Length = 491
Score = 134 bits (336), Expect = 2e-31
Identities = 83/252 (32%), Positives = 127/252 (50%), Gaps = 42/252 (16%)
Query: 186 RDCQELFQVGERQSGLFEIQPQGS-PPFLVNCKM-TSDGGWTVIQRRHDGSVDFNRPWEA 243
++C+E+ + G S ++ IQP S P+ V C M T +GGWTVIQ R DGSVDF R W+
Sbjct: 239 KECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDP 298
Query: 244 YKAGFGDP------------HGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQFSV 291
YK GFG+ GE+WLG +K+ +T + L +++ DW G+ +
Sbjct: 299 YKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGD----KVKA 354
Query: 292 HLGG-----EDTAYSLQL-----TAPVAGQLGATTVPPSGLSVP------FSTWDQDHD- 334
H GG E Y + + TA A GA+ + ++ FST+D+D+D
Sbjct: 355 HYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDG 414
Query: 335 -LRRD--KNCAKSLSGGWWFGTCSHSNLNGQYF----RSIPQQRQKLKKGIFWKTWRGRY 387
L D K C+K GGWW+ C +N NG+Y+ + + G+ W W+G +
Sbjct: 415 WLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSW 474
Query: 388 YPLQATTMLIQP 399
Y ++ +M I+P
Sbjct: 475 YSMRKMSMKIRP 486
>gi|5730075 fibrinogen-like 2 precursor [Homo sapiens]
Length = 439
Score = 132 bits (333), Expect = 4e-31
Identities = 75/220 (34%), Positives = 111/220 (50%), Gaps = 30/220 (13%)
Query: 182 HRLPRDCQELFQVGERQSGLFEIQPQG-SPPFLVNCKM-TSDGGWTVIQRRHDGSVDFNR 239
H + +DC + + +G+R S + + P + F V C M T GGWTV+Q R DGS +F R
Sbjct: 207 HLIYKDCSDYYAIGKRSSETYRVTPDPKNSSFEVYCDMETMGGGWTVLQARLDGSTNFTR 266
Query: 240 PWEAYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDG------------NAELL 287
W+ YKAGFG+ EFWLG +K+H +T + L + L D++G E L
Sbjct: 267 TWQDYKAGFGNLRREFWLGNDKIHLLTKSKEMILRIDLEDFNGVELYALYDQFYVANEFL 326
Query: 288 QFSVHLGGED--TAYSLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSL 345
++ +H+G + +L+ L T P D+D+D NC
Sbjct: 327 KYRLHVGNYNGTAGDALRFNKHYNHDLKFFTTP-----------DKDNDRYPSGNCGLYY 375
Query: 346 SGGWWFGTCSHSNLNGQYFRSIPQQRQKLKKGIFWKTWRG 385
S GWWF C +NLNG+Y+ Q+ + ++ GIFW TW G
Sbjct: 376 SSGWWFDACLSANLNGKYYH---QKYRGVRNGIFWGTWPG 412
>gi|157384973 tenascin R [Homo sapiens]
Length = 1358
Score = 127 bits (318), Expect = 2e-29
Identities = 77/218 (35%), Positives = 106/218 (48%), Gaps = 13/218 (5%)
Query: 185 PRDCQELFQVGERQSGLFEIQPQG--SPPFLVNCKMTSDGG-WTVIQRRHDGSVDFNRPW 241
P+DC + G+ SG++ I G S V C MT+DGG W V QRR +G DF R W
Sbjct: 1135 PQDCAQHLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKW 1194
Query: 242 EAYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQFSVHLGGEDTAYS 301
Y+ GFG+ EFWLGL+ +H IT L V +RD A + Y
Sbjct: 1195 ADYRVGFGNVEDEFWLGLDNIHRITSQGRYELRVDMRDGQEAAFASYDRFSVEDSRNLYK 1254
Query: 302 LQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSHSNLNG 361
L++ G G + G PFST D+D+D+ NCA S G WW+ C +NLNG
Sbjct: 1255 LRI-GSYNGTAGDSLSYHQGR--PFSTEDRDNDV-AVTNCAMSYKGAWWYKNCHRTNLNG 1310
Query: 362 QYFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQP 399
+Y S + +GI W W+G + + M ++P
Sbjct: 1311 KYGES------RHSQGINWYHWKGHEFSIPFVEMKMRP 1342
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,673,316
Number of Sequences: 37866
Number of extensions: 792982
Number of successful extensions: 2854
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 49
Number of HSP's that attempted gapping in prelim test: 2587
Number of HSP's gapped (non-prelim): 182
length of query: 406
length of database: 18,247,518
effective HSP length: 105
effective length of query: 301
effective length of database: 14,271,588
effective search space: 4295747988
effective search space used: 4295747988
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.