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Search of human proteins with 21389509
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21389509 KPL2 protein isoform 2 [Homo sapiens]
(514 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21389509 KPL2 protein isoform 2 [Homo sapiens] 1009 0.0
gi|145699133 KPL2 protein isoform 1 [Homo sapiens] 996 0.0
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 62 2e-09
gi|148746195 trichohyalin [Homo sapiens] 59 1e-08
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 59 1e-08
gi|147903302 MAP7 domain containing 3 [Homo sapiens] 56 9e-08
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 56 9e-08
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 55 1e-07
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 54 3e-07
gi|94721321 coiled-coil domain containing 11 [Homo sapiens] 54 3e-07
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 53 8e-07
gi|92859701 myosin VI [Homo sapiens] 52 1e-06
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 52 1e-06
gi|109134347 NY-REN-58 antigen [Homo sapiens] 52 1e-06
gi|109134355 NY-REN-58 antigen [Homo sapiens] 52 1e-06
gi|148612801 KIAA1009 protein [Homo sapiens] 52 1e-06
gi|42794779 myosin 18A isoform b [Homo sapiens] 51 2e-06
gi|28416946 myosin 18A isoform a [Homo sapiens] 51 2e-06
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 51 3e-06
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 51 3e-06
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 51 3e-06
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 51 3e-06
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 51 3e-06
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 51 3e-06
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 51 3e-06
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 51 3e-06
gi|21735548 centrosomal protein 2 [Homo sapiens] 50 6e-06
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 49 1e-05
gi|38569484 kinesin family member 21A [Homo sapiens] 49 1e-05
gi|225579095 S-phase cyclin A-associated protein in the ER isofo... 49 1e-05
>gi|21389509 KPL2 protein isoform 2 [Homo sapiens]
Length = 514
Score = 1009 bits (2608), Expect = 0.0
Identities = 514/514 (100%), Positives = 514/514 (100%)
Query: 1 MSEILCQWLNKELKVSRTVSPKSFAKAFSSGYLLGEVLHKFELQDDFSEFLDSRVSSAKL 60
MSEILCQWLNKELKVSRTVSPKSFAKAFSSGYLLGEVLHKFELQDDFSEFLDSRVSSAKL
Sbjct: 1 MSEILCQWLNKELKVSRTVSPKSFAKAFSSGYLLGEVLHKFELQDDFSEFLDSRVSSAKL 60
Query: 61 NNFSRLEPTLNLLGVQFDQNVAHGIITEKPGVATKLLYQLYIALQKKKKSGLTGVEMQTM 120
NNFSRLEPTLNLLGVQFDQNVAHGIITEKPGVATKLLYQLYIALQKKKKSGLTGVEMQTM
Sbjct: 61 NNFSRLEPTLNLLGVQFDQNVAHGIITEKPGVATKLLYQLYIALQKKKKSGLTGVEMQTM 120
Query: 121 QRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLHFEKLER 180
QRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLHFEKLER
Sbjct: 121 QRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLHFEKLER 180
Query: 181 FQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMMKKKKE 240
FQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMMKKKKE
Sbjct: 181 FQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMMKKKKE 240
Query: 241 AEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQKRLEED 300
AEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQKRLEED
Sbjct: 241 AEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQKRLEED 300
Query: 301 AFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQLMHVRHEKE 360
AFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQLMHVRHEKE
Sbjct: 301 AFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQLMHVRHEKE 360
Query: 361 VLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKEKRFHDQIAVERAQA 420
VLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKEKRFHDQIAVERAQA
Sbjct: 361 VLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKEKRFHDQIAVERAQA 420
Query: 421 RYEKHYSVCAEILDQIVDLSTKVADYRMLTNNLIPYKLMHDWKELFFNAKPIYEQASVKT 480
RYEKHYSVCAEILDQIVDLSTKVADYRMLTNNLIPYKLMHDWKELFFNAKPIYEQASVKT
Sbjct: 421 RYEKHYSVCAEILDQIVDLSTKVADYRMLTNNLIPYKLMHDWKELFFNAKPIYEQASVKT 480
Query: 481 LPANPSREQLTELEKRDLLDTNDYEEYKVPTDMK 514
LPANPSREQLTELEKRDLLDTNDYEEYKVPTDMK
Sbjct: 481 LPANPSREQLTELEKRDLLDTNDYEEYKVPTDMK 514
>gi|145699133 KPL2 protein isoform 1 [Homo sapiens]
Length = 1822
Score = 996 bits (2576), Expect = 0.0
Identities = 508/508 (100%), Positives = 508/508 (100%)
Query: 1 MSEILCQWLNKELKVSRTVSPKSFAKAFSSGYLLGEVLHKFELQDDFSEFLDSRVSSAKL 60
MSEILCQWLNKELKVSRTVSPKSFAKAFSSGYLLGEVLHKFELQDDFSEFLDSRVSSAKL
Sbjct: 1 MSEILCQWLNKELKVSRTVSPKSFAKAFSSGYLLGEVLHKFELQDDFSEFLDSRVSSAKL 60
Query: 61 NNFSRLEPTLNLLGVQFDQNVAHGIITEKPGVATKLLYQLYIALQKKKKSGLTGVEMQTM 120
NNFSRLEPTLNLLGVQFDQNVAHGIITEKPGVATKLLYQLYIALQKKKKSGLTGVEMQTM
Sbjct: 61 NNFSRLEPTLNLLGVQFDQNVAHGIITEKPGVATKLLYQLYIALQKKKKSGLTGVEMQTM 120
Query: 121 QRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLHFEKLER 180
QRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLHFEKLER
Sbjct: 121 QRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLHFEKLER 180
Query: 181 FQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMMKKKKE 240
FQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMMKKKKE
Sbjct: 181 FQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMMKKKKE 240
Query: 241 AEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQKRLEED 300
AEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQKRLEED
Sbjct: 241 AEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQKRLEED 300
Query: 301 AFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQLMHVRHEKE 360
AFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQLMHVRHEKE
Sbjct: 301 AFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQLMHVRHEKE 360
Query: 361 VLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKEKRFHDQIAVERAQA 420
VLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKEKRFHDQIAVERAQA
Sbjct: 361 VLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKEKRFHDQIAVERAQA 420
Query: 421 RYEKHYSVCAEILDQIVDLSTKVADYRMLTNNLIPYKLMHDWKELFFNAKPIYEQASVKT 480
RYEKHYSVCAEILDQIVDLSTKVADYRMLTNNLIPYKLMHDWKELFFNAKPIYEQASVKT
Sbjct: 421 RYEKHYSVCAEILDQIVDLSTKVADYRMLTNNLIPYKLMHDWKELFFNAKPIYEQASVKT 480
Query: 481 LPANPSREQLTELEKRDLLDTNDYEEYK 508
LPANPSREQLTELEKRDLLDTNDYEEYK
Sbjct: 481 LPANPSREQLTELEKRDLLDTNDYEEYK 508
Score = 29.6 bits (65), Expect = 6.9
Identities = 15/62 (24%), Positives = 29/62 (46%)
Query: 220 PASNRTLKALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTD 279
P S+ L E + M+ + A+E+K ++ +K +A+ A L G++ D
Sbjct: 643 PVSDEVLPETEGETMLSANADKTPKAEEVKSSDSFLKLTTRAQLGAKSEQLLKKGKSIPD 702
Query: 280 LL 281
+L
Sbjct: 703 VL 704
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 61.6 bits (148), Expect = 2e-09
Identities = 63/308 (20%), Positives = 145/308 (47%), Gaps = 30/308 (9%)
Query: 121 QRLTNLRLQNMKSDTFQERL---RHMIPRQ------TDFNLMRITYRFQEKYKHVKEDLA 171
Q L+ + Q K+D + E L R + + TD L + QEK + V+ + +
Sbjct: 167 QALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKS 226
Query: 172 HLHFE------KLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRT 225
+ KLER + L +Q+ E +L + Q+ + AK+QA Q+ +
Sbjct: 227 EIQLNVKELKRKLERAKLLLPQQQ-LQAEADHLGKELQS-VSAKLQA---QVEENELWNR 281
Query: 226 LKALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYS 285
L + +KM +++++ ++ ++I++ E I++ + + + + +
Sbjct: 282 LNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 341
Query: 286 DDEYIKKIQKRLEEDAFAREQREKRRRK-LLMDQLIAHEAQEEAYREEQLINRLMRQSQQ 344
+E I+++++++ E REQ EKR+ + + +Q E + + +R+E+ I R+ ++
Sbjct: 342 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI----REQEE 397
Query: 345 ERRIAVQLMHVRHEK-----EVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDF 399
+ R ++M + EK E +W+ ++Q E+ R ++ + + ++ KI
Sbjct: 398 KIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 457
Query: 400 EEQFLKEK 407
+E+ ++E+
Sbjct: 458 QEEMMQEQ 465
Score = 42.4 bits (98), Expect = 0.001
Identities = 69/386 (17%), Positives = 171/386 (44%), Gaps = 43/386 (11%)
Query: 49 EFLDSRVSSAKLNNFS---RLEPTLNLLGVQFDQNVAHGIITEKPGVATKLLYQ-----L 100
+ ++S S +LN +LE LL Q Q A + E V+ KL Q L
Sbjct: 219 QLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENEL 278
Query: 101 YIALQKKKKSGLTGVEMQTMQRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQ 160
+ L ++++ + E + +R ++ Q K +E++R + R Q
Sbjct: 279 WNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWE---KEEKMRRQ 335
Query: 161 EKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKP 220
E+ KE+ EK+ +K++E++ ++Q + R+ E + +A + + +
Sbjct: 336 EEMMWEKEEKIRELEEKMHEQEKIREQEE----KRQEEEKIREQEKRQEQEAKMWRQEEK 391
Query: 221 ASNRTLKALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDL 280
+ K E ++MM++++E +E K +E ++++Q +E +
Sbjct: 392 IREQEEKIREQEEMMQEQEEKMGEQEE-KMWEQ--EEEMQEQEEKMRRQ----------- 437
Query: 281 LNTYSDDEYIKKIQKRL-EEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLM 339
+E I++ +K++ E++ REQ E + + ++ + + + +E ++ +
Sbjct: 438 ------EEKIREQEKKIREQEEKIREQEEMMQEQ---EEKMGEQEGKMCEQEAKMQEQEE 488
Query: 340 RQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDF 399
+ +QE +I Q +R ++E + + ++Q E+ ++ + E ++ K+
Sbjct: 489 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 548
Query: 400 EEQFLKEKRFHDQIAVERAQARYEKH 425
+E+ ++E+ ++ + + + + ++H
Sbjct: 549 QEEKMREQ----EVRLRQQEEKMQEH 570
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 58.9 bits (141), Expect = 1e-08
Identities = 59/294 (20%), Positives = 131/294 (44%), Gaps = 17/294 (5%)
Query: 137 QERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQ 196
QERL ++ D L R +QE+ + E+ E+ Q K + +++
Sbjct: 158 QERLEQRDRQRRDEELWRQRQEWQEREERRAEE---------EQLQSCKGHETEEFPDEE 208
Query: 197 YLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMMKK----KKEAEDVADEIKKFE 252
L RR E+ K + Q + +R + E ++ K+ +KE E + +E + +
Sbjct: 209 QLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQ 268
Query: 253 ALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQK--RLEEDAFAREQREKR 310
++++ + + L Q ++ +++ Q+ R E+ REQ+E+R
Sbjct: 269 RELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERR 328
Query: 311 RRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFRE 370
++ + QEE R EQ + R + ++E+++ + R E+++ + ++ RE
Sbjct: 329 EQQEERREQQLRREQEE--RREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRRE 386
Query: 371 KQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKEKRFHDQIAVERAQARYEK 424
+Q + + L RE L ++ ++ E+Q +E++ + ER + ++E+
Sbjct: 387 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQ 440
Score = 57.4 bits (137), Expect = 3e-08
Identities = 68/325 (20%), Positives = 143/325 (44%), Gaps = 47/325 (14%)
Query: 105 QKKKKSGLTGVEMQTMQRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYK 164
Q ++KS + L R + ++++ Q+R + +P + + R R +EK
Sbjct: 772 QAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKEL 831
Query: 165 HVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNR 224
E+ L ++ ER Q+L+EE+ +++ RR Q + + ++ +
Sbjct: 832 QFLEEEEQL--QRRERAQQLQEEED--GLQEDQERRRSQEQRRDQKWRWQLEEERKRRRH 887
Query: 225 TLKALEA-QKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNT 283
TL A A Q+ ++K+++ +E + E K+ Q +E
Sbjct: 888 TLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQER------------------- 928
Query: 284 YSDDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLI----NRLM 339
+Y ++ Q + EE+ RE+REKRRR + +E YR+++ + +L+
Sbjct: 929 ----QYREEEQLQQEEEQLLREEREKRRR----------QERERQYRKDKKLQQKEEQLL 974
Query: 340 RQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDF 399
+ ++RR + R E+E+ + ++ E+RR ++++ ++ L ++
Sbjct: 975 GEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQE----- 1029
Query: 400 EEQFLKEKRFHDQIAVERAQARYEK 424
EEQ L+E+R ++ Q R E+
Sbjct: 1030 EEQLLREEREKRRLQERERQYREEE 1054
Score = 54.7 bits (130), Expect = 2e-07
Identities = 57/286 (19%), Positives = 128/286 (44%), Gaps = 14/286 (4%)
Query: 139 RLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYL 198
R R + R+ + L + Q + + +E L L ++L R ++ +EEQ+ + ++
Sbjct: 247 RKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRR-ERQEEEQQQQRLRREQQ 305
Query: 199 NRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMMKKKKEAEDVADEIKKFEALIKKD 258
RR+Q E + Q + + R + E ++ ++++ E ++++ + +++
Sbjct: 306 LRRKQEEERREQQ----EERREQQERREQQEERREQQLRREQEERREQQLRREQEEERRE 361
Query: 259 LQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQ 318
Q + + + + L ++ +++ Q+ E REQ+ +R ++L +Q
Sbjct: 362 QQLRREQEEERREQQLRREQQLRR----EQQLRREQQLRREQQLRREQQLRREQQLRREQ 417
Query: 319 LIAHEAQEEAYREEQLINRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRL 378
+ E Q R EQ R ++ +QERR Q + E+ W R ++HE+ R
Sbjct: 418 QLRREQQ---LRREQEEERHEQKHEQERR--EQRLKREQEERRDWLKREEETERHEQERR 472
Query: 379 KDFQDALDREAALAKQAKIDFEEQFLKEKRFHDQIAVERAQARYEK 424
K E + K++ EE+ +++R Q+ E+ + R ++
Sbjct: 473 KQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQR 518
Score = 53.9 bits (128), Expect = 3e-07
Identities = 68/299 (22%), Positives = 129/299 (43%), Gaps = 39/299 (13%)
Query: 127 RLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLHFEKLERFQKLKE 186
R Q +K + QE R + R+ + R Q+ + +E E+ ER+ KL+E
Sbjct: 443 REQRLKRE--QEERRDWLKREEETERHEQERRKQQLKRDQEE-------ERRERWLKLEE 493
Query: 187 EQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMMKKKKEAEDVAD 246
E+R E++ RR+ E ++ +K+++E E +
Sbjct: 494 EERREQQERREQQLRREQEE-----------------------RREQRLKRQEEEERLQQ 530
Query: 247 EIKKFEALIKKDLQAKESASKTSLDTA-GQTTTDLLNTYSDDEYIKKIQKRLEEDAFARE 305
++ + L ++ + +E K + Q + +E ++ KR EE R+
Sbjct: 531 RLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEE---RRQ 587
Query: 306 QREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQLMHVRHEKEVLWQN 365
QR KR ++ ++Q + E E +EE+ RL R+ +E R QL+ ++E Q
Sbjct: 588 QRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEER-RQQLLKSEEQEERRQQQ 646
Query: 366 RIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKEKRFHDQIAVERAQARYEK 424
+++ E+RLK ++ E L ++ + + EQ L E+ + A ER ++R K
Sbjct: 647 LRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEE--EQEQARERIKSRIPK 703
Score = 52.8 bits (125), Expect = 8e-07
Identities = 72/318 (22%), Positives = 140/318 (44%), Gaps = 31/318 (9%)
Query: 118 QTMQRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLHFEK 177
Q ++R LR + Q R + R+ + R Q+ + +E+ E+
Sbjct: 381 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQ 440
Query: 178 LERFQKLKEEQRCFDIEKQYLNRRRQ---NEIMAKIQAAIIQIPKPASNRTLKALEAQKM 234
R Q+LK EQ + + +L R + +E + Q + R LK E ++
Sbjct: 441 ERREQRLKREQ---EERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERR 497
Query: 235 MKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSD--DEYIKK 292
++++ + + E ++ +++ + K + L ++ L + ++ +K+
Sbjct: 498 EQQERREQQLRREQEE-----RREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKR 552
Query: 293 IQ-KRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQ 351
+ KRLE++ REQR KR ++ DQL+ E EE+ RL R+ QE R+ +
Sbjct: 553 EEEKRLEQER--REQRLKREQEERRDQLLKRE-------EERRQQRLKRE--QEERLEQR 601
Query: 352 LMH---VRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKEKR 408
L R E+E + R+ RE+ EERR + + E +Q ++ E+Q +E+R
Sbjct: 602 LKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEE---RRQQQLRREQQERREQR 658
Query: 409 FHDQIAVERAQARYEKHY 426
+ ER + R ++ +
Sbjct: 659 LKREEEEERLEQRLKREH 676
Score = 52.8 bits (125), Expect = 8e-07
Identities = 56/255 (21%), Positives = 116/255 (45%), Gaps = 29/255 (11%)
Query: 157 YRFQEKYKHVKEDLAHLHFEKL---ERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAA 213
YR +K + +E L EK ER +K +EE+ E+Q L R+ + +
Sbjct: 960 YRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWE-- 1017
Query: 214 IIQIPKPASNRTLKALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTA 273
+ + E ++++++++E + + +++ +++LQ +E
Sbjct: 1018 -----RQYRKKDELQQEEEQLLREEREKRRLQERERQYRE--EEELQQEEE------QLL 1064
Query: 274 GQTTTDLLNTYSDDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQ 333
G+ + +Y K+ + + EE+ RE+ EKRRR+ Q +EE +EE+
Sbjct: 1065 GEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQC---REEEELQQEEE 1121
Query: 334 LINRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAK 393
+L+R+ +++RR R E+EV + ++ E+RR ++ + E L +
Sbjct: 1122 ---QLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQ 1178
Query: 394 QAKIDFEEQFLKEKR 408
+ EEQ L+E++
Sbjct: 1179 E-----EEQLLREEQ 1188
Score = 52.0 bits (123), Expect = 1e-06
Identities = 60/301 (19%), Positives = 145/301 (48%), Gaps = 28/301 (9%)
Query: 114 GVEMQTMQRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHL 173
G E + ++L + +L++ +S Q+ L+H++ Q + + + R+Q++ +H E+
Sbjct: 1244 GRENEQFRQLEDSQLRDRQS---QQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLE 1300
Query: 174 HFEKLE---RFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALE 230
E+ E R +K +EE++ E++ RR++ + + + ++Q R + L
Sbjct: 1301 REEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQ------EREEQPLR 1354
Query: 231 AQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYI 290
Q+ +K +E E + + +K L+ ++ + + L ++ +
Sbjct: 1355 RQERDRKFREEE------LRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQL 1408
Query: 291 KKIQKRL---EEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERR 347
++ + R EE +R++R+++ R+ +Q + + +E + EE+ +L ++ ++ R
Sbjct: 1409 RQDRDRKFREEEQQLSRQERDRKFRE--EEQQVRRQERERKFLEEE--QQLRQERHRKFR 1464
Query: 348 IAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKEK 407
QL+ R E+++ Q R + + E++ + +D RE L Q + E +FL+E+
Sbjct: 1465 EEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQ---EPERKFLEEE 1521
Query: 408 R 408
+
Sbjct: 1522 Q 1522
Score = 48.1 bits (113), Expect = 2e-05
Identities = 61/323 (18%), Positives = 138/323 (42%), Gaps = 32/323 (9%)
Query: 160 QEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPK 219
+EK + + +L E+ R Q+ +E++R F + Q + + + + +
Sbjct: 736 EEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPL----R 791
Query: 220 PASNRTLKALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTD 279
R L+A E Q+ ++ E+ ++ ++ +K+LQ E + Q +
Sbjct: 792 EQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQE 851
Query: 280 LLNTYSDDEYIKKIQKRLEEDAFA---REQREKRR----------RKLLMDQLIAHEAQE 326
+ +D+ ++ Q++ + + E+R++RR +L +Q + E +E
Sbjct: 852 EEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEE 911
Query: 327 EAYREEQLINRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALD 386
E REE+ R+ +QER+ + + E+++L + R R +Q ER+ + +
Sbjct: 912 ELQREER---EKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQ 968
Query: 387 REAAL-----AKQAKIDFEEQFLKEKRF---HDQIAVERAQAR----YEKHYSVCAEILD 434
+E L K+ + + E+++ +E+ +Q+ E + R +E+ Y E+
Sbjct: 969 KEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ 1028
Query: 435 QIVDLSTKVADYRMLTNNLIPYK 457
+ L + + R L Y+
Sbjct: 1029 EEEQLLREEREKRRLQERERQYR 1051
Score = 47.8 bits (112), Expect = 2e-05
Identities = 56/251 (22%), Positives = 118/251 (47%), Gaps = 44/251 (17%)
Query: 158 RFQEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQI 217
R QE+ + +E+ L E+ + ++ +E++R + E+QY R+ ++ K + + +
Sbjct: 922 RRQEQERQYREE-EQLQQEEEQLLREEREKRRRQERERQY---RKDKKLQQKEEQLLGEE 977
Query: 218 PKPASNRTLKALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTT 277
P+ Q+ KK +E E++ E E L++++ + +
Sbjct: 978 PEKRRR--------QEREKKYREEEELQQEE---EQLLREEREKRRRQEW---------- 1016
Query: 278 TDLLNTYSDDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINR 337
+ +Y KK + + EE+ RE+REKRR L ++ + +EE +EE+ +
Sbjct: 1017 --------ERQYRKKDELQQEEEQLLREEREKRR---LQERERQYREEEELQQEEEQL-- 1063
Query: 338 LMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKI 397
L + + RR ++ + + E+ + ++ RE+ E+RR ++ + E L ++
Sbjct: 1064 LGEERETRRRQELERQYRKEEELQQEEEQLLREEP-EKRRRQERERQCREEEELQQE--- 1119
Query: 398 DFEEQFLKEKR 408
EEQ L+E+R
Sbjct: 1120 --EEQLLREER 1128
Score = 46.6 bits (109), Expect = 5e-05
Identities = 59/293 (20%), Positives = 124/293 (42%), Gaps = 51/293 (17%)
Query: 116 EMQTMQRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLHF 175
E + ++ LR Q + Q+R R + + +F+E+ + V+ F
Sbjct: 1389 ERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKF 1448
Query: 176 EKLERFQKLKEEQ-RCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKM 234
LE Q+L++E+ R F E+Q L R + ++ + R K LE ++
Sbjct: 1449 --LEEEQQLRQERHRKFREEEQLLQEREEQQLHRQ-------------ERDRKFLEEEQQ 1493
Query: 235 MKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQ 294
+++++ ++ + + +K L+ ++ + ++ +
Sbjct: 1494 LRRQERDRKFREQELRSQEPERKFLEEEQQLHRQ----------------------QRQR 1531
Query: 295 KRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQLMH 354
K L+E+ R Q ++R+ D+ E Q REEQ ++R +++R+ ++
Sbjct: 1532 KFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSR----QERDRKFRLEEQK 1587
Query: 355 VRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKEK 407
VR ++ Q R F E + + RR ++ Q L +E + K +EQ L+E+
Sbjct: 1588 VRRQE----QERKFMEDEQQLRR-QEGQQQLRQE----RDRKFREDEQLLQER 1631
Score = 46.6 bits (109), Expect = 5e-05
Identities = 66/314 (21%), Positives = 139/314 (44%), Gaps = 29/314 (9%)
Query: 137 QERLRHMIPRQT---DFNLMRITYRFQEKYKHVKEDLAHLHFE------KLERFQKLKEE 187
QER + RQ F L R QE+ + ED L + + ER +K +E+
Sbjct: 1565 QEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFRED 1624
Query: 188 QRCF-DIEKQYLNRRRQNEIMAKIQAAIIQIPKPAS---NRTLKALEAQKMMKKKKEAED 243
++ + E+Q L+R+ ++ + + + + + +R K E ++++++ +E +
Sbjct: 1625 EQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQL 1684
Query: 244 VADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIK------------ 291
E + ++ L+ +E K + +L + ++E ++
Sbjct: 1685 RRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQE 1744
Query: 292 KIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQ 351
+ +K LEE+ E+ E++ R+ D+ E Q REEQ + ++S ++ R Q
Sbjct: 1745 RYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLR--SQESDRKFREEEQ 1802
Query: 352 LMHVRHEKEVLWQNRIFREKQHEER-RLKDFQDALDREAALAKQAKIDFEEQFLKEKRFH 410
L R E+++ Q R + + EE+ +L++ + L +E +A+ F Q K +R
Sbjct: 1803 LRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQ-EKSRREE 1861
Query: 411 DQIAVERAQARYEK 424
++ E Q R ++
Sbjct: 1862 QELWQEEEQKRRQE 1875
Score = 45.8 bits (107), Expect = 9e-05
Identities = 49/240 (20%), Positives = 118/240 (49%), Gaps = 14/240 (5%)
Query: 158 RFQEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQI 217
R QE+ K +E+ L E+ + ++ +E++R + E+QY R+++E+ + + + +
Sbjct: 982 RRQEREKKYREE-EELQQEEEQLLREEREKRRRQEWERQY---RKKDELQQEEEQLLREE 1037
Query: 218 --PKPASNRTLKALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQ 275
+ R + E +++ +++++ E ++ + L ++ + +E + +
Sbjct: 1038 REKRRLQERERQYREEEELQQEEEQLLGEERETRRRQEL-ERQYRKEEELQQEEEQLLRE 1096
Query: 276 TTTDLLNTYSDDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLI 335
+ + ++ + + EE+ RE+REKRRR+ L Q + +EE +EE+
Sbjct: 1097 EPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQ---YREEEEVQQEEE-- 1151
Query: 336 NRLMRQSQQERRIAVQLMHVRHEKEVLW-QNRIFREKQHEERRLKDFQDALDREAALAKQ 394
+L+R+ ++RR R E+E+ + ++ RE+Q + R+ ++ Q + E K+
Sbjct: 1152 -QLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKR 1210
Score = 45.8 bits (107), Expect = 9e-05
Identities = 36/155 (23%), Positives = 68/155 (43%), Gaps = 23/155 (14%)
Query: 291 KKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINR------------- 337
++ +K EE RE+RE++RR+ D+ E Q REEQ + R
Sbjct: 1309 RRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELR 1368
Query: 338 -------LMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAA 390
+ + Q+ RR + ++ E+++ Q R + +Q +R+ ++ + L R+
Sbjct: 1369 HQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQE- 1427
Query: 391 LAKQAKIDFEEQFLKEKRFHDQIAVERAQARYEKH 425
+ K EEQ ++ + + E Q R E+H
Sbjct: 1428 --RDRKFREEEQQVRRQERERKFLEEEQQLRQERH 1460
Score = 43.1 bits (100), Expect = 6e-04
Identities = 69/315 (21%), Positives = 132/315 (41%), Gaps = 41/315 (13%)
Query: 127 RLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLHFEKLE-RFQKLK 185
R Q +KS+ +ER + + R+ R +++ K +E+ E+LE R ++
Sbjct: 630 RQQLLKSEEQEERRQQQLRREQQ-------ERREQRLKREEEE------ERLEQRLKREH 676
Query: 186 EEQRCFDIEKQYLNRRRQNEIMAKIQAAII----QIPKPASNRTLKALEAQKMMKKKKEA 241
EE+R +Q L Q + +I++ I Q+ A R K + + ++
Sbjct: 677 EEER----REQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRR 732
Query: 242 EDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQKRLEEDA 301
++ ++ ++ E+ +LQ +E + D + +E ++ ++RL
Sbjct: 733 QEQEEKRRRRES----ELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARP 788
Query: 302 FAREQREKRRR---KLLMDQLIAHEAQEEAYREEQLINR------LMRQSQQERRIAVQL 352
REQRE++ R + +Q E +E+ R Q R L + Q +RR Q
Sbjct: 789 PLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQ 848
Query: 353 MHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQ---AKIDFEEQFLKEKRF 409
+ E+E Q R + E+RR + ++ L+ E + AK +EQ KE++
Sbjct: 849 L---QEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQL 905
Query: 410 HDQIAVERAQARYEK 424
+ E + EK
Sbjct: 906 LQEEEEELQREEREK 920
Score = 42.7 bits (99), Expect = 8e-04
Identities = 54/224 (24%), Positives = 109/224 (48%), Gaps = 27/224 (12%)
Query: 158 RFQEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQI 217
R QE+ + +E+ L ++ ER + L+EEQ+ + +Q L R+ + E + + Q+
Sbjct: 1685 RRQERDRKFREEEQQLRRQERER-KFLQEEQQ---LRRQELERKFREEEQLRQETEQEQL 1740
Query: 218 PKPASNRTLKALEAQKMMKKKKEAEDVADEI-KKFEALIKKDLQAKESASKTSLDTAGQT 276
+ R K LE +++ +++E + E +KF +++ Q ++ + L +
Sbjct: 1741 RR--QERYRKILEEEQLRPEREEQQLRRQERDRKF----REEEQLRQEREEQQLRSQESD 1794
Query: 277 TTDLLNTYSDDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLIN 336
+ ++E ++ Q+R EE +QR+ + R ++ + E QE+ R+E+
Sbjct: 1795 -----RKFREEEQLR--QER-EEQQLRPQQRDGKYR--WEEEQLQLEEQEQRLRQER--- 1841
Query: 337 RLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKD 380
RQ + E + A Q R E+E LWQ + +Q ER+L++
Sbjct: 1842 --DRQYRAEEQFATQEKSRREEQE-LWQEEEQKRRQERERKLRE 1882
Score = 40.4 bits (93), Expect = 0.004
Identities = 66/355 (18%), Positives = 146/355 (41%), Gaps = 66/355 (18%)
Query: 106 KKKKSGLTGVEMQTMQRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKH 165
++++ L G E +T +R L Q K + Q+ ++ + + R QE+ +
Sbjct: 1057 QQEEEQLLGEERETRRR-QELERQYRKEEELQQEEEQLLREEPEKR------RRQERERQ 1109
Query: 166 VKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRT 225
+E+ L E+ + ++ +E++R ++E+QY R + E+ + + + + P+ +
Sbjct: 1110 CREE-EELQQEEEQLLREEREKRRRQELERQY---REEEEVQQEEEQLLREEPEKRRRQE 1165
Query: 226 LKALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSL-----------DTAG 274
L+ ++ +++E + + +E +K ++ + +E + D
Sbjct: 1166 LERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKW 1225
Query: 275 QTTTDLLNTYSDDEYIKK-----------------------IQKRLEEDAFAREQREKRR 311
Q + N D++ K +Q L E ++E+RR
Sbjct: 1226 QWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRR 1285
Query: 312 -----RKLLMDQLIAHEAQEEA-------------YREEQLINRLMRQSQQERRIAVQLM 353
R ++ + E Q+EA REE+ R +++ ++ R QL+
Sbjct: 1286 WQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLL 1345
Query: 354 HVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKEKR 408
R E+ + Q R + ++ E R + + L+ E L +Q + E +FLKE++
Sbjct: 1346 QEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQER---ERKFLKEEQ 1397
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 58.5 bits (140), Expect = 1e-08
Identities = 74/354 (20%), Positives = 163/354 (46%), Gaps = 49/354 (13%)
Query: 121 QRLTNLRLQNMKSDTFQERL---RHMIPRQ------TDFNLMRITYRFQEKYKHVKEDLA 171
Q L+ + Q K+D + E L R + + TD L + QEK + V+ + +
Sbjct: 179 QALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKS 238
Query: 172 HLHFE------KLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRT 225
+ KLER + L +Q+ E +L + Q+ + AK+QA Q+ +
Sbjct: 239 EIQLNVKELKRKLERAKLLLPQQQ-LQAEADHLGKELQS-VSAKLQA---QVEENELWNR 293
Query: 226 LKALEAQKMMKKKKEAEDVADEIKKFEALIKK-DLQAKESASKTSLDTAGQTTTDLLNTY 284
L + +KM +++++ ++ ++I++ E I++ + + +E K +
Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 353
Query: 285 SDDEYIKKIQK--RLEEDAFAREQREKRRRKLLM--------------DQLIAHEAQEEA 328
++ +K +K R EE + +E++ +R+ +++ +Q E +E+
Sbjct: 354 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 413
Query: 329 YREEQLINRLMRQSQ------QERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQ 382
EE++ + RQ Q QE +I Q +R +++ +W+ EK HE+ ++++ +
Sbjct: 414 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQ---EEKIHEQEKIREEE 470
Query: 383 DALDREAALAKQAKIDFEEQFLKEK-RFHDQIAVERAQARYEKHYSVCAEILDQ 435
++E ++ KI +E+ ++K + H+Q E+ + + EK + +I +Q
Sbjct: 471 KRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQ--EEKIRKQEEKVWRQEEKIREQ 522
Score = 51.6 bits (122), Expect = 2e-06
Identities = 55/288 (19%), Positives = 134/288 (46%), Gaps = 22/288 (7%)
Query: 158 RFQEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQI 217
R QE+ KE+ EK+ +K++E++ ++Q + R+ E + +A + +
Sbjct: 380 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEE----KRQEEEKIREQEKRQEQEAKMWRQ 435
Query: 218 PKPASNRTLKALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTT 277
+ + K E +K M +++E ++I++ E K+ Q + + + +
Sbjct: 436 EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE---KRQEQEEMWRQEEKIHEQEEIW 492
Query: 278 TDLLNTYSDDEYIKKIQKRL--------EEDAFAREQREK--RRRKLLMDQLIAHEAQEE 327
+ +E I+K ++++ E++ REQ EK R+ + + +Q +E+
Sbjct: 493 RQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEK 552
Query: 328 AYREEQLINRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDR 387
+ +E++ RQ +QE ++ Q +R ++E +W+ +Q E+R+ ++ +
Sbjct: 553 MHEQEKIWEEEKRQ-EQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQE 611
Query: 388 EAALAKQAKIDFEEQFLKEK----RFHDQIAVERAQARYEKHYSVCAE 431
E ++ KI +E+ ++E+ R +++ E+ + E+ +C +
Sbjct: 612 EKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQ 659
Score = 45.4 bits (106), Expect = 1e-04
Identities = 44/228 (19%), Positives = 110/228 (48%), Gaps = 17/228 (7%)
Query: 158 RFQEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNR----RRQNEIMAKIQAA 213
R QE+ +E+ E +K+ E+++ ++ EK+ R++ +I + +
Sbjct: 527 REQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKV 586
Query: 214 IIQIPKPASNRTLKALEAQKMMKKKKEAEDVADEIKKFEALIKKD---LQAKESASKTSL 270
Q K + + +KM K++++ + ++I++ E I++ ++ +E ++
Sbjct: 587 WRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQE 646
Query: 271 DTAGQTTTDLLNTYSDDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYR 330
+ G+ + E +K+Q++ EE + +E++ + + K + +Q QEE +
Sbjct: 647 EKMGEQEEKMC------EQEEKMQEQ-EETMWRQEEKIREQEKKIREQEEKIREQEEMMQ 699
Query: 331 E--EQLINRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEER 376
E E++ + + +QE ++ Q +R ++E +W+ + R +Q EE+
Sbjct: 700 EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV-RLRQQEEK 746
Score = 45.1 bits (105), Expect = 2e-04
Identities = 59/326 (18%), Positives = 153/326 (46%), Gaps = 20/326 (6%)
Query: 118 QTMQRLTNLRLQNMKSDTFQERLRHMIPRQT-DFNLMRITYRFQEKYKHVKEDLAHL--H 174
+ M +R Q K +E++R RQ + + R + +E+ + ++E +
Sbjct: 398 EKMHEQEKIREQEEKRQE-EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQ 456
Query: 175 FEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKM 234
EK+ +K++EE++ + E+ + RQ E + + + Q K + +K+
Sbjct: 457 EEKIHEQEKIREEEKRQEQEEMW----RQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKV 512
Query: 235 MKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQ 294
+++++ + ++I++ E + + Q ++ + + + + + +++ ++
Sbjct: 513 WRQEEKIREQEEKIREQEEKMWR--QEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQED 570
Query: 295 KRLEEDAFAREQREK--RRRKLLMDQLIAHEAQEEAY--REEQLINRLMRQSQQERRIAV 350
K ++ REQ EK R+ + + +Q + QEE +EE++ + + +QE +I
Sbjct: 571 KMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIRE 630
Query: 351 QLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQA-KIDFEEQFLKEK-- 407
Q +R E+E + Q + + + EE+ + + ++E + +Q KI +E+ ++E+
Sbjct: 631 QEEKIR-EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEE 689
Query: 408 --RFHDQIAVERAQARYEKHYSVCAE 431
R +++ E+ + +E+ +C +
Sbjct: 690 KIREQEEMMQEQEEKMWEQEEKMCEQ 715
Score = 41.6 bits (96), Expect = 0.002
Identities = 57/299 (19%), Positives = 138/299 (46%), Gaps = 21/299 (7%)
Query: 137 QERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLHFEKLERFQKL-KEEQRCF---- 191
QE++R RQ + R QE+ H +E++ + E+ +K+ K+E++ +
Sbjct: 463 QEKIREEEKRQEQEEMWR-----QEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEE 517
Query: 192 DIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMMKKKKEAEDVADEIKKF 251
I +Q R Q E M + Q I+ + K E +K+ +++K E D++ +
Sbjct: 518 KIREQEEKIREQEEKMWR-QEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQ-EDKMWRQ 575
Query: 252 EALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQKRLEE-DAFAREQREKR 310
E I++ + + + + + +E I++ +++++E + REQ EK
Sbjct: 576 EEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKI 635
Query: 311 RRKLLMDQ----LIAHEAQEEAYREEQLINRLMRQSQQERRIAVQLMHVRHEKEVLWQNR 366
R + M Q + + ++ +EE++ + +QE +I Q +R ++E + +
Sbjct: 636 REQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQE 695
Query: 367 IFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKEKRFHDQIAVERAQARYEKH 425
++Q EE+ + + ++E + +Q + + + +EK + ++ + + + + ++H
Sbjct: 696 EMMQEQ-EEKMWEQEEKMCEQEEKMQEQEE---KMRRQEEKMWEQEVRLRQQEEKMQEH 750
>gi|147903302 MAP7 domain containing 3 [Homo sapiens]
Length = 876
Score = 55.8 bits (133), Expect = 9e-08
Identities = 54/201 (26%), Positives = 96/201 (47%), Gaps = 38/201 (18%)
Query: 225 TLKALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTY 284
TL A +KKKKE V+ + EAL ++ + +ES +K+ T ++N
Sbjct: 548 TLSVQSASSTVKKKKET--VSKTTNRCEALSQRHMIYEESGNKS--------TAGIMNAE 597
Query: 285 SDDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQ 344
+ + + ++++ AREQREK +EE + E++ R++++S+
Sbjct: 598 AATKILTELRR------LAREQREK---------------EEEERQREEMQQRVIKKSKD 636
Query: 345 ERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAK-QAKIDFEEQF 403
+ AV H K Q +Q+E ++ K + D D+EA L K AKI +E+
Sbjct: 637 MAKEAVGGQAEDHLKLKDGQ------QQNETKKKKGWLDQEDQEAPLQKGDAKIKAQEEA 690
Query: 404 LKEKRFHDQIAVERAQARYEK 424
K K+ H++I ++ Q R E+
Sbjct: 691 DKRKKEHERIMLQNLQERLER 711
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 55.8 bits (133), Expect = 9e-08
Identities = 69/300 (23%), Positives = 132/300 (44%), Gaps = 33/300 (11%)
Query: 135 TFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIE 194
T Q M P ++M+ F ++ ++ D ++LE ++ +E ++ +
Sbjct: 498 TVQRNQMLMTPTSAPRSVMK---SFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQK 554
Query: 195 KQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMMK--KKKEAEDVADEIKKFE 252
+ RRR E+ K + + + L+A E + MK KKK+ E +I +
Sbjct: 555 VEEDKRRRLEEVKLKREERL--------RKVLQARERVEQMKEEKKKQIEQKFAQIDEKT 606
Query: 253 ALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQKRLEEDAFAREQREKRRR 312
K++ A+E A K + A + ++ +E ++++ +E+ E+R +
Sbjct: 607 EKAKEERLAEEKAKKKA---AAKKMEEVEARRKQEEEARRLRW------LQQEEEERRHQ 657
Query: 313 KLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQ 372
+LL + E ++E R+ RL Q +QERR + R E+E Q R +E+Q
Sbjct: 658 ELLQKK---KEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQ 714
Query: 373 -------HEERRLKDFQDALDREAALAKQ-AKIDFEEQFLKEKRFHDQIAVERAQARYEK 424
E+ RL+ ++ +RE AL Q ++ E + K+K ++A + Q EK
Sbjct: 715 LAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEK 774
Score = 51.2 bits (121), Expect = 2e-06
Identities = 56/274 (20%), Positives = 133/274 (48%), Gaps = 30/274 (10%)
Query: 127 RLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLHFEKLERFQKLKE 186
RL+N++ E+LR + R E+ K +E+ + ER +++KE
Sbjct: 537 RLENLRRKEEAEQLRRQKVEEDK-------RRRLEEVKLKREERLRKVLQARERVEQMKE 589
Query: 187 EQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMMKKKKEAEDVA- 245
E++ IE+++ + E + + A + K A+ + ++ +EA++ K+++EA +
Sbjct: 590 EKKK-QIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARR--KQEEEARRLRW 646
Query: 246 ----DEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQKRLEEDA 301
+E ++ + L++K + ++ + + + ++ Q+R E++
Sbjct: 647 LQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAE-------------QREQERREQER 693
Query: 302 FAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQLMHVRHEKEV 361
+E+RE+ RR+ + A++E RE++ + + QER A++L + ++E+
Sbjct: 694 REQERREQERREQERREQERQLAEQERRREQERLQ--AERELQEREKALRLQKEQLQREL 751
Query: 362 LWQNRIFREKQHEERRLKDFQDALDREAALAKQA 395
+ + +++ ER+L++ Q+ +EAA A +A
Sbjct: 752 EEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKA 785
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 55.5 bits (132), Expect = 1e-07
Identities = 62/259 (23%), Positives = 117/259 (45%), Gaps = 33/259 (12%)
Query: 179 ERFQKLKEEQRCFDIEKQYLN---RRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMM 235
+R + L+ ++ + +Q + RRR E+ K + + + L+A E + M
Sbjct: 540 QRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERL--------RKVLQARERVEQM 591
Query: 236 K--KKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKI 293
K KKK+ E +I + K++ A+E A K + A + ++ +E +++
Sbjct: 592 KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKA---AAKKMEEVEARRKQEEEARRL 648
Query: 294 QKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQLM 353
+ +E+ E+R ++LL + E ++E R+ RL Q +QERR +
Sbjct: 649 R------WLQQEEEERRHQELLQKK---KEEEQERLRKAAEAKRLAEQREQERREQERRE 699
Query: 354 HVRHEKEVLWQNRIFREKQ-------HEERRLKDFQDALDREAALAKQ-AKIDFEEQFLK 405
R E+E Q R +E+Q E+ RL+ ++ +RE AL Q ++ E + K
Sbjct: 700 QERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKK 759
Query: 406 EKRFHDQIAVERAQARYEK 424
+K ++A + Q EK
Sbjct: 760 KKEEQQRLAERQLQEEQEK 778
Score = 51.2 bits (121), Expect = 2e-06
Identities = 56/274 (20%), Positives = 133/274 (48%), Gaps = 30/274 (10%)
Query: 127 RLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLHFEKLERFQKLKE 186
RL+N++ E+LR + R E+ K +E+ + ER +++KE
Sbjct: 541 RLENLRRKEEAEQLRRQKVEEDK-------RRRLEEVKLKREERLRKVLQARERVEQMKE 593
Query: 187 EQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMMKKKKEAEDVA- 245
E++ IE+++ + E + + A + K A+ + ++ +EA++ K+++EA +
Sbjct: 594 EKKK-QIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARR--KQEEEARRLRW 650
Query: 246 ----DEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQKRLEEDA 301
+E ++ + L++K + ++ + + + ++ Q+R E++
Sbjct: 651 LQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAE-------------QREQERREQER 697
Query: 302 FAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQLMHVRHEKEV 361
+E+RE+ RR+ + A++E RE++ + + QER A++L + ++E+
Sbjct: 698 REQERREQERREQERREQERQLAEQERRREQERLQ--AERELQEREKALRLQKEQLQREL 755
Query: 362 LWQNRIFREKQHEERRLKDFQDALDREAALAKQA 395
+ + +++ ER+L++ Q+ +EAA A +A
Sbjct: 756 EEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKA 789
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 54.3 bits (129), Expect = 3e-07
Identities = 70/354 (19%), Positives = 155/354 (43%), Gaps = 51/354 (14%)
Query: 116 EMQTMQRLTNLRLQNMKSDTFQERLRHMIP--RQTDFNLMRITYRFQEKYKHVKEDLAHL 173
E + ++ +R Q K +ERLR R+ + + R R +E+ K ++E L
Sbjct: 278 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKEL 337
Query: 174 HFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQK 233
+K R Q+ + +++ + +Q R Q E M + + + + K + K + ++
Sbjct: 338 REQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 397
Query: 234 MM----KKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEY 289
M ++ +E E+ E +K ++K + K+ + + T D ++E
Sbjct: 398 RMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQE------KKTRDQEEKMQEEER 451
Query: 290 IKKIQKRL-EEDAFAREQREK----------------------RRRKLLMDQLIAHEAQE 326
I++ +K++ EE+ REQ EK +++ L +Q E +E
Sbjct: 452 IREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE 511
Query: 327 EAYREEQLIN-------------RLMRQSQQERRIAVQLMHVRHEKEVLW--QNRIFREK 371
+ + +E+ I R + +QE ++ Q +R +++ +W + R+ ++
Sbjct: 512 KIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKT 571
Query: 372 QHEERRLKDFQDAL-DREAALAKQAKIDFEEQFLKEKRFHDQIAVERAQARYEK 424
Q +E++ D ++ + + E ++ K+ EE+ ++E+ Q E+ Q + EK
Sbjct: 572 QEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEK 625
Score = 43.1 bits (100), Expect = 6e-04
Identities = 37/213 (17%), Positives = 103/213 (48%), Gaps = 8/213 (3%)
Query: 230 EAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEY 289
+ +KM +++K + E+++ E +++ + +E + + +++
Sbjct: 312 QEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKM 371
Query: 290 IKKIQKRLEEDAFAREQREKRR--RKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERR 347
++ ++ E++ REQ +K R + + +Q +EE RE++ + + + ++E++
Sbjct: 372 WRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKK 431
Query: 348 IAVQLMHVRHEKEVLWQNRIFREKQ----HEERRLKDFQDALDR-EAALAKQAKIDFEEQ 402
+ Q R ++E + + RE++ EE +++ ++ + + E + +Q + ++++Q
Sbjct: 432 MQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQ 491
Query: 403 FLKEKRFHDQIAVERAQARYEKHYSVCAEILDQ 435
L E++ E+ Q + EK + +I DQ
Sbjct: 492 RLPEQK-EKLWEQEKMQEQEEKIWEQEEKIRDQ 523
Score = 42.4 bits (98), Expect = 0.001
Identities = 43/247 (17%), Positives = 116/247 (46%), Gaps = 17/247 (6%)
Query: 182 QKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMMKKKKEA 241
+K++EE+R + EK+ R + E+M + + + + + + K E ++ M++++E
Sbjct: 583 EKMREEERMREREKKM---REEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEE- 638
Query: 242 EDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQKRLEEDA 301
K +E K Q ++ + L + + ++ ++ +K E++
Sbjct: 639 -------KMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEK 691
Query: 302 FAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQLMHVRHEKEV 361
++ +E+ ++ +++ E+ E ++ + +MR+ QE ++ Q ++ ++E
Sbjct: 692 MEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMRE--QEEKMQEQEEKMQEQEEE 749
Query: 362 LWQNR----IFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKEKRFHDQIAVER 417
+W+ EK E++RL + ++ L + +Q KI +E+ ++++ + E+
Sbjct: 750 MWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEK 809
Query: 418 AQARYEK 424
+ + EK
Sbjct: 810 MRGQEEK 816
Score = 40.8 bits (94), Expect = 0.003
Identities = 46/272 (16%), Positives = 126/272 (46%), Gaps = 24/272 (8%)
Query: 160 QEKYKHVKEDLAHLHFEKL-ERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIP 218
++K K +++ EK+ E+ +K+++++ + EK+ + + E ++ Q
Sbjct: 495 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWE---QEE 551
Query: 219 KPASNRTLKALEAQKMMKKKKEAE----DVADEIKKFEALIKKDLQAKESASKTSLDTAG 274
K + ++M KK +E E D +++++ E + +++ + +E
Sbjct: 552 KMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE--------- 602
Query: 275 QTTTDLLNTYSD--DEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREE 332
+++ + E +K+Q++ EE + +E++ + + + + +Q QEE E+
Sbjct: 603 ----EMMREQEEKMQEQEEKMQEQ-EEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ 657
Query: 333 QLINRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALA 392
Q + + + ++ Q E+++ Q ++ ++ Q +E++ D + + E+
Sbjct: 658 QRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRE 717
Query: 393 KQAKIDFEEQFLKEKRFHDQIAVERAQARYEK 424
++ K+ EE+ ++E+ Q E+ Q + E+
Sbjct: 718 REKKMREEEEMMREQEEKMQEQEEKMQEQEEE 749
Score = 39.3 bits (90), Expect = 0.009
Identities = 51/259 (19%), Positives = 120/259 (46%), Gaps = 24/259 (9%)
Query: 176 EKLERF-QKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKM 234
+K +R+ ++L +E+ +E Y N E+ K ++P S ++ L +++
Sbjct: 193 KKADRYIEELTKERDALSLEL-YRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKEL 251
Query: 235 MKKKKEAEDVADEIKKF---EALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIK 291
+K + A+ + +++ E + +++ + +E K + +E ++
Sbjct: 252 KRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEE--------KMWRQEERLR 303
Query: 292 KIQKRL---EEDAFAREQREKRRRKLLMDQ-LIAHEAQEEAYREEQLINRLMRQSQQERR 347
+ + ++ EE + +E+R + + K L +Q E +E +EEQ+ + + +QE +
Sbjct: 304 EQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEK 363
Query: 348 IAVQLMHVRHEKEVLW-QNRIFREKQ-----HEERRLKDFQDALDREAALAKQAKI-DFE 400
+ Q + ++E LW Q + RE++ EER + + ++E + +Q K+ +
Sbjct: 364 MREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQV 423
Query: 401 EQFLKEKRFHDQIAVERAQ 419
E+ +EK+ +Q R Q
Sbjct: 424 EKMREEKKMQEQEKKTRDQ 442
Score = 37.0 bits (84), Expect = 0.043
Identities = 48/283 (16%), Positives = 136/283 (48%), Gaps = 18/283 (6%)
Query: 160 QEKYKHVKEDLAHLHFEKLERFQKL-KEEQRCFDIEKQYLNRRRQNEIMAKI-QAAIIQI 217
+EK + +E + + E+ +K+ ++E++ ++ E++ ++R E K+ + +Q
Sbjct: 616 EEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQE 675
Query: 218 PKPASNRTLKALEAQKMMKKKKEAEDVA---DEIKKFEALIKKDLQAKESASKTSLDTAG 274
+ + K E +KM KK +E E +++++ E++ +++ + +E
Sbjct: 676 QEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEK 735
Query: 275 QTTTDLLNTYSDDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYR---- 330
+ ++E ++ +K E++ EQ+ +K ++L HE +E +
Sbjct: 736 MQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQK---EKLWEHEKMQEQEKIWEQ 792
Query: 331 EEQLINRLMRQSQQERRIAVQLMHVRHEKEVLW--QNRIFREKQH---EERRLKDFQDAL 385
EE++ ++ + QE ++ Q +R ++E +W + +++ +++ +E ++ ++ +
Sbjct: 793 EEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKM 852
Query: 386 DREAALAKQAKIDFEEQFLKEKRFHDQIAVERAQARYEKHYSV 428
+ E ++ K+ +E+ ++ + + E+ + + EK Y V
Sbjct: 853 E-EKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKIYCV 894
>gi|94721321 coiled-coil domain containing 11 [Homo sapiens]
Length = 514
Score = 54.3 bits (129), Expect = 3e-07
Identities = 68/330 (20%), Positives = 151/330 (45%), Gaps = 50/330 (15%)
Query: 116 EMQTMQRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLHF 175
EMQ + + M+ T + ++ RQ DF ++ +F+E+ + ++ +L +H
Sbjct: 115 EMQLKKETIEEKKDRMREKTKLLKEKNEKERQ-DFVAEKLDQQFRERCEELRVELLSIHQ 173
Query: 176 EKL----------------------ERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAA 213
+K+ + F KL EE R +++ RRQ E+M +
Sbjct: 174 KKVCEERKAQIAFNEELSRQKLVEEQMFSKLWEEDRLAKEKREAQEARRQKELMENTRLG 233
Query: 214 IIQIPKPASNRTLKALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESA---SKTSL 270
+ A ++KA + K++EA V + + ++D+ K+ A ++T L
Sbjct: 234 L-----NAQITSIKAQRQATQLLKEEEARLVESNNAQIKHENEQDMLKKQKAKQETRTIL 288
Query: 271 DTAGQTTTD-LLNTYSDDE--YIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAH----E 323
A Q + + Y D++ +K +Q+ L++ ++++++R ++ +Q I H +
Sbjct: 289 QKALQERIEHIQQEYRDEQDLNMKLVQRALQDLQEEADKKKQKREDMIREQKIYHKYLAQ 348
Query: 324 AQEEAYREEQLINRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQD 383
+EE +E+ +R++ + + +++A + +R EKE R ++ R+L+ Q+
Sbjct: 349 RREEEKAQEKEFDRIL-EEDKAKKLAEKDKELRLEKEA---RRQLVDEVMCTRKLQ-VQE 403
Query: 384 ALDREAALAKQAKIDFEEQFLKEKRFHDQI 413
L REA + EE+ +++K ++ +
Sbjct: 404 KLQREAK-------EQEERAMEQKHINESL 426
Score = 42.0 bits (97), Expect = 0.001
Identities = 66/298 (22%), Positives = 125/298 (41%), Gaps = 51/298 (17%)
Query: 93 ATKLLYQLYIALQKKKKSGLTGVEMQTMQRLTNLRLQNMKSDT-------FQERLRHMIP 145
AT+LL + L + + + Q M L+ Q K +T QER+ H+
Sbjct: 247 ATQLLKEEEARLVESNNAQIKHENEQDM-----LKKQKAKQETRTILQKALQERIEHIQQ 301
Query: 146 RQTDFNLMRITYRFQEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNE 205
D + + K V+ L L E ++ QK ++ R I +YL +RR+ E
Sbjct: 302 EYRDEQDLNM--------KLVQRALQDLQEEADKKKQKREDMIREQKIYHKYLAQRREEE 353
Query: 206 IMAKIQAAIIQIPKPASNRTLKALEAQKMMKKKKEAEDVADEIKKF--EALIKKDLQAKE 263
+ + +R L+ +A+K+ +K KE + ++ E + + LQ +E
Sbjct: 354 ----------KAQEKEFDRILEEDKAKKLAEKDKELRLEKEARRQLVDEVMCTRKLQVQE 403
Query: 264 SASKTSLDTAGQTTTDLLNTYSDDEYIKKIQKRL---EEDAFAREQR-EKRRRKLLMDQL 319
+ + + + + ++I + K L E++ FAR QR + RK L Q+
Sbjct: 404 KLQREAKEQEERAM--------EQKHINESLKELNCEEKENFARRQRLAQEYRKQLQMQI 455
Query: 320 IAHEAQEEAYREEQLINRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERR 377
+ +EA +EE ++ + E +A M + +EVL +++ + H R+
Sbjct: 456 AYQQQSQEAEKEE-------KRREFEAGVAANKMCLDKVQEVLSTHQVLPQNIHPMRK 506
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 52.8 bits (125), Expect = 8e-07
Identities = 54/283 (19%), Positives = 135/283 (47%), Gaps = 16/283 (5%)
Query: 154 RITYRFQEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAA 213
R+ + +EK +E + + E+ +K++E++ I +Q RRQ E+M + +
Sbjct: 354 RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE--KIREQEEKMRRQEEMMWEKEEK 411
Query: 214 IIQIPKPASNRTLKALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTA 273
+ + + + K ++MM +K+E +E + I++ + ++ K
Sbjct: 412 MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK 471
Query: 274 GQTTTDLLNTYSDDEYIKKIQKRL---EEDAFAREQREKRRRKLLMDQLIAHEAQEEAYR 330
Q + + +E I++ ++++ EE + +E++ + K+ ++ + QEE +R
Sbjct: 472 RQEQEAKM--WRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEE--KRQEQEEMWR 527
Query: 331 EEQLINRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQH-EERRLKDFQDALDREA 389
+E+ I +Q+ +I Q +R ++E +W+ EK H +E ++++ ++ + R+
Sbjct: 528 QEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQ---EEKMHDQEEKIREQEEKVWRQE 584
Query: 390 ALAKQAKIDFEEQFLKEK-RFHDQIAVERAQARYEKHYSVCAE 431
++ + EQ +EK R +++ E+ + E+ +C +
Sbjct: 585 EKIREQEEKIREQ--EEKIREQEEMTQEQEEKMGEQEEKMCEQ 625
Score = 49.7 bits (117), Expect = 6e-06
Identities = 56/302 (18%), Positives = 137/302 (45%), Gaps = 26/302 (8%)
Query: 118 QTMQRLTNLRLQNMKSDTFQERLRHMIPRQT-DFNLMRITYRFQEKYKHVKEDLAHL--H 174
+ M +R Q K +E++R RQ + + R + +E+ + ++E +
Sbjct: 445 EKMHEQEKIREQEEKRQE-EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQ 503
Query: 175 FEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKM 234
EK+ +K++EE++ + E+ + RQ E + + + Q K + +KM
Sbjct: 504 EEKIHEQEKIREEEKRQEQEEMW----RQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKM 559
Query: 235 MKKKKEAEDVADEIKKFEALI-KKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKI 293
+++++ D ++I++ E + +++ + +E K + + +++ ++
Sbjct: 560 WRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQE 619
Query: 294 QKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQLM 353
+K E++ +EQ EK RR QEE RE++ R +QE +I Q
Sbjct: 620 EKMCEQEEKMQEQEEKMRR------------QEEKIREQEKKIR-----EQEEKIREQEE 662
Query: 354 HVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKEKRFHDQI 413
++ ++E +W+ +Q E+ + ++ + E ++ ++ +E+ ++E + H +
Sbjct: 663 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 722
Query: 414 AV 415
A+
Sbjct: 723 AI 724
Score = 48.9 bits (115), Expect = 1e-05
Identities = 49/266 (18%), Positives = 120/266 (45%), Gaps = 35/266 (13%)
Query: 176 EKLERF-QKLKEEQRCFDIE--KQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQ 232
+K +R+ ++L +E+ +E + + E AK+Q + + S L E +
Sbjct: 250 KKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELK 309
Query: 233 KMMKKKK----------EAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLN 282
+ +++ K EA+ + E++ A ++ ++ E ++ LN
Sbjct: 310 RKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR-------------LN 356
Query: 283 TYSDDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQS 342
+++ ++ +K E + +EQ EK R + ++ I + ++ +EE + + +
Sbjct: 357 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQ---EEKIREQEEKMRRQEEMMWEKEEKMR 413
Query: 343 QQERRIAVQLMHVRHEKEVLWQN----RIFREKQHEERRLKDFQDALDREAALAKQAKID 398
+QE + + +R ++E++W+ R EK HE+ ++++ ++ E + +Q K
Sbjct: 414 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK-- 471
Query: 399 FEEQFLKEKRFHDQIAVERAQARYEK 424
+EQ K R ++I + + R ++
Sbjct: 472 RQEQEAKMWRQEEKIREQEEKIREQE 497
Score = 45.4 bits (106), Expect = 1e-04
Identities = 49/271 (18%), Positives = 122/271 (45%), Gaps = 22/271 (8%)
Query: 160 QEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPK 219
+EK + +E + E+ +K++ ++ +++ + RRQ E+M + + I ++ +
Sbjct: 388 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM--RRQEEMMWEKEEKIRELEE 445
Query: 220 PASNRTL------KALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTA 273
+ K E +K+ +++K E A ++ E + +++ + +E K
Sbjct: 446 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQE- 504
Query: 274 GQTTTDLLNTYSDDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQ 333
+ E I++ +KR E++ R++ + R ++ + Q QEE R+++
Sbjct: 505 --------EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQE 556
Query: 334 LINRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAK 393
+ +QE ++ Q +R ++E +W+ +Q E+ R ++ + E +
Sbjct: 557 -----EKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQ 611
Query: 394 QAKIDFEEQFLKEKRFHDQIAVERAQARYEK 424
+ K+ +E+ + E+ Q E+ + + EK
Sbjct: 612 EEKMGEQEEKMCEQEEKMQEQEEKMRRQEEK 642
Score = 42.4 bits (98), Expect = 0.001
Identities = 54/280 (19%), Positives = 128/280 (45%), Gaps = 31/280 (11%)
Query: 158 RFQEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQI 217
R QE+ KE+ EK+ +K++E++ E++ + ++ E AK+ +I
Sbjct: 427 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 486
Query: 218 PKPASNRTLKALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTT 277
+ + + + +K E E + +E K+ E ++++ +E + + Q
Sbjct: 487 REQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQE---QEEMWRQEEKIREQEEIWRQKE 543
Query: 278 TDLLNTYSDDEYIKKIQKRL-EEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLIN 336
+ +E I+K ++++ ++ +Q EK R E +E+ +R+E+ I
Sbjct: 544 ----KIHEQEEKIRKQEEKMWRQEEKMHDQEEKIR-----------EQEEKVWRQEEKIR 588
Query: 337 RLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQA- 395
+QE +I Q +R E+E + Q + + + EE+ + + ++E + +Q
Sbjct: 589 ------EQEEKIREQEEKIR-EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEE 641
Query: 396 KIDFEEQFLKEK----RFHDQIAVERAQARYEKHYSVCAE 431
KI +E+ ++E+ R +++ E+ + +E+ +C +
Sbjct: 642 KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQ 681
>gi|92859701 myosin VI [Homo sapiens]
Length = 1285
Score = 52.4 bits (124), Expect = 1e-06
Identities = 67/302 (22%), Positives = 131/302 (43%), Gaps = 30/302 (9%)
Query: 213 AIIQIPKPASNRTLKALEAQ--KMMKKKKEAEDVADEIKK-FEALIKKDLQAKESASKTS 269
++++ KP N+ +K LE +M K K ++I+K ++AL+K + + K
Sbjct: 858 SVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKK 917
Query: 270 LDTAGQTTTDLLNTYSDDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAY 329
+ E +++IQ+ +E++ RE+ EKRRRK ++ + E + +
Sbjct: 918 QQE------------EEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRK 965
Query: 330 REEQLINRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREA 389
+EE+ R R+ ++R A + +KE Q + E++ +R L + A
Sbjct: 966 QEEE--ERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELA-LRIAQSEAE 1022
Query: 390 ALAKQAKIDF---EEQFLKEKRFHDQIAVERAQ--ARYEKHYSVCAEILDQIVDLST-KV 443
++ +A+ D + K +Q+A E ++ +R + A + DLS K
Sbjct: 1023 LISDEAQADLALRRNDGTRPKMTPEQMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKWKY 1082
Query: 444 ADYRMLTNNLIPYKLMHDWKELFFNAKPIYEQASVKTLPANPSREQLTELEKRDLLDTND 503
A+ R N +L+ +E F +Y K ++++ TE E+R D
Sbjct: 1083 AELRDTINTSCDIELLAACREEFHRRLKVYHAWKSK------NKKRNTETEQRAPKSVTD 1136
Query: 504 YE 505
Y+
Sbjct: 1137 YD 1138
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 52.4 bits (124), Expect = 1e-06
Identities = 58/265 (21%), Positives = 117/265 (44%), Gaps = 45/265 (16%)
Query: 180 RFQKLKEEQRCFD-IEKQYLNRRRQNEIMAKIQAAI---IQIPKPASNRTLKALEAQKMM 235
R QK K E+ F+ +EK ++ E K++A + I+ + S +L+ Q++
Sbjct: 402 REQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQ-QELS 460
Query: 236 KKKKEAEDVA-----DEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTY---SDD 287
+ K+E DV ++I K + L +K+L KE L T + + + S
Sbjct: 461 RVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQS 520
Query: 288 EYIKKIQKRLEEDAFAREQREKRRRKLLMD---QLIAHEAQEEAYR------EEQLINRL 338
EY+K Q++ ++++ A E+ E +++ +L + +L + + E YR E L L
Sbjct: 521 EYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSL 580
Query: 339 MRQSQQERRIAV----------------------QLMHVRHEKEVLWQNRIFREKQHEER 376
Q + +AV +L ++H+++ LW ++ KQ +
Sbjct: 581 QENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQT 640
Query: 377 RLKDFQDALDRE-AALAKQAKIDFE 400
++ ++ ++E L K +I F+
Sbjct: 641 EMEKLREKCEQEKETLLKDKEIIFQ 665
Score = 44.3 bits (103), Expect = 3e-04
Identities = 59/314 (18%), Positives = 136/314 (43%), Gaps = 19/314 (6%)
Query: 116 EMQTMQRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLHF 175
E+ ++ T+ Q +++ +++ H +Q D + Q K +K+ + L
Sbjct: 706 ELSVLKDQTDKMKQELEAKMDEQKNHHQ--QQVDSIIKEHEVSIQRTEKALKDQINQLEL 763
Query: 176 EKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMM 235
ER + LKE Q + + + R A + + Q + A++ KA E Q
Sbjct: 764 LLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQ 823
Query: 236 KKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTY--SDDEYIKKI 293
++K + + I + + + + Q K+ T LD DL+ + E +K+
Sbjct: 824 LQQKLLDLETERILLTKQVAEVEAQKKDVC--TELDAHKIQVQDLMQQLEKQNSEMEQKV 881
Query: 294 -------QKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQER 346
+ +LE+ +++E+ ++ L+ + + + +E +E +++ + + +
Sbjct: 882 KSLTQVYESKLED---GNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSI 938
Query: 347 RIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKE 406
I + + + + ++ ++ + + LK + LD+EA L K+ + E KE
Sbjct: 939 HILNEEYETKFKNQEKKMEKVKQKAKEMQETLK--KKLLDQEAKLKKELENTALELSQKE 996
Query: 407 KRFHDQIAVERAQA 420
K+F+ ++ +E AQA
Sbjct: 997 KQFNAKM-LEMAQA 1009
Score = 41.2 bits (95), Expect = 0.002
Identities = 83/439 (18%), Positives = 176/439 (40%), Gaps = 63/439 (14%)
Query: 40 KFELQDDFSEFLDSRVSSAKLNNFSRLEPTLNLLGVQFDQNVAHGIITEKPGVATKLLYQ 99
K E+ + D V + S E ++ L Q+D+ ++ + ++ K+
Sbjct: 1366 KVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCE-LLDQVQDLSFKV--- 1421
Query: 100 LYIALQKKKKSGLTGVEMQTMQRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRF 159
L K+K S L V+ + N S+ ++ Q ++I
Sbjct: 1422 --DTLSKEKISALEQVDDWS----------NKFSEWKKKAQSRFTQHQNTVKELQIQLEL 1469
Query: 160 QEKYKHVKEDLAHLHFEKLE----RFQKLKEEQRCFDIEKQYLNRRRQN-EIMAKIQAA- 213
+ K + K++ +L E+L+ RF LK E + +K + ++ N E K Q A
Sbjct: 1470 KSKEAYEKDEQINLLKEELDQQNKRFDCLKGEM---EDDKSKMEKKESNLETELKSQTAR 1526
Query: 214 IIQIPKPASNRTLKALEAQKMMKKKKEAEDV-----ADEIKKFEAL-IKKDLQAKES--- 264
I+++ + +T++ +++K + +D+ +++ F+ L +KD + KE+
Sbjct: 1527 IMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEK 1586
Query: 265 ---------ASKTSLDTAGQTTTDL-LNTYSDDEYIKKIQKRLEEDAFAREQREKRR--- 311
+ K L+T + + L+ S +E +K ++ RLE ++ A+ KR+
Sbjct: 1587 ILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQ 1646
Query: 312 -----RKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQLMHVRHEK----EVL 362
+K L+ Q+ E Q + E L + ++ER + H+ EK E
Sbjct: 1647 KIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREV-----HILEEKLKSVESS 1701
Query: 363 WQNRIFREKQHEERRLKDFQDALDREAALAK--QAKIDFEEQFLKEKRFHDQIAVERAQA 420
+ + + Q+ D + + K + KI ++ L EK Q + +
Sbjct: 1702 QSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEE 1761
Query: 421 RYEKHYSVCAEILDQIVDL 439
H+ + + ++++ L
Sbjct: 1762 TVSSHFEMRCQYQERLIKL 1780
Score = 40.8 bits (94), Expect = 0.003
Identities = 64/288 (22%), Positives = 134/288 (46%), Gaps = 31/288 (10%)
Query: 138 ERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEK-Q 196
E L+ + RQ NL++ R +E + KE L EK ++L E R ++EK +
Sbjct: 282 ETLQQRVKRQE--NLLK---RCKETIQSHKEQCTLLTSEKEALQEQLDE--RLQELEKIK 334
Query: 197 YLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMMK-----KKKEAEDVADEIKKF 251
L+ + +++ +++ A I + ++ + E ++ M K++E + IK+
Sbjct: 335 DLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQM 394
Query: 252 EALIKKDLQAKESASKTS-------LDTAGQTTTDLLNTYSD-DEYIKKIQKRLEEDAFA 303
++ + KE + + + L TA +T ++ DE IK I+K EE+ +
Sbjct: 395 TTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERIS 454
Query: 304 REQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQLMHVRHEKEVLW 363
+Q R ++ ++D ++ ++E+ + ++L + + + +QE +Q E+E
Sbjct: 455 LQQELSRVKQEVVD-VMKKSSEEQIAKLQKLHEKELARKEQELTKKLQ----TREREFQE 509
Query: 364 QNRIFREKQHEE----RRLKDFQDALD-REAALAKQAKIDFEEQFLKE 406
Q ++ EK E + K+ Q++L E L K+A + E L++
Sbjct: 510 QMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRD 557
Score = 37.0 bits (84), Expect = 0.043
Identities = 80/390 (20%), Positives = 174/390 (44%), Gaps = 54/390 (13%)
Query: 107 KKKSGLTGVEMQTMQR-LTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKH 165
K+K L G E + M + +T L+ + +K DT L+ + +++ + Q++ K
Sbjct: 1077 KQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKS----AHVNSLAQDETKL 1132
Query: 166 VKEDLAHLHFEKLERFQKLKEEQRCFD--IEKQYL---NRRRQNEIMAKIQAAI--IQIP 218
AHL +++ + LKE + +E + L ++R+ +E+ +K++ Q
Sbjct: 1133 K----AHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSL 1188
Query: 219 KPASNRTLKALEAQKMMKKKKEAEDVADEI----KKFEALIKKDLQAKESASKTSLDTAG 274
K + ++ K+LE K ++ KK +E++A ++ KK EAL+ E+ + ++ +
Sbjct: 1189 KSSHEKSNKSLE-DKSLEFKKLSEELAIQLDICCKKTEALL-------EAKTNELINISS 1240
Query: 275 QTTTDLLNTYSDDEY-IKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQ 333
T +L+ S ++ K+++ L + E + R+L +Q + + ++A
Sbjct: 1241 SKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQA----- 1295
Query: 334 LINRLMRQSQQERRIAVQLMHVRHEKEVLW-----QNRIFREKQHEERRLK-DFQDALDR 387
++L + Q + + + + EKE L Q + EK+ +LK + + ++
Sbjct: 1296 -THQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINA 1354
Query: 388 EAALAKQAKIDFEEQFLKEKRFHD-QIAVERAQARYEKHYSVCA----------EILDQI 436
+ ++ K E K+ D + ++ + + EK ++ + E+LDQ+
Sbjct: 1355 VTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQV 1414
Query: 437 VDLSTKVADYRMLTNNLIPYKLMHDWKELF 466
DLS KV + + + + DW F
Sbjct: 1415 QDLSFKVD--TLSKEKISALEQVDDWSNKF 1442
Score = 35.0 bits (79), Expect = 0.16
Identities = 45/238 (18%), Positives = 108/238 (45%), Gaps = 20/238 (8%)
Query: 161 EKYKHVKEDLAHLHFEKLE-RFQKLKEEQRCFDIEKQYLNRRRQNEI-MAKIQAAIIQIP 218
E+ K +E LA L + L+ +++ ++ ++E Q + + + ++Q + Q+
Sbjct: 812 EQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLE 871
Query: 219 KPASNRTLKALEAQKMMKKKKEAEDVADEIKKFEALIKKD---LQAKESASK-----TSL 270
K S K ++ + K E + E K + L++K+ LQ +E K T
Sbjct: 872 KQNSEMEQKVKSLTQVYESKLEDGNKEQEQTK-QILVEKENMILQMREGQKKEIEILTQK 930
Query: 271 DTAGQTTTDLLNTYSDDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYR 330
+A + + +LN + ++ + +K + A+E +E ++KLL +EA
Sbjct: 931 LSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLL---------DQEAKL 981
Query: 331 EEQLINRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDRE 388
+++L N + SQ+E++ +++ + + + R + +++ +++ + RE
Sbjct: 982 KKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRE 1039
Score = 29.6 bits (65), Expect = 6.9
Identities = 47/224 (20%), Positives = 95/224 (42%), Gaps = 23/224 (10%)
Query: 234 MMKKKKEA--EDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDE--Y 289
++ +KEA E + + +++ E + KDL E KT L T + +L+ D+
Sbjct: 311 LLTSEKEALQEQLDERLQELEKI--KDLHMAE---KTKLITQLRDAKNLIEQLEQDKGMV 365
Query: 290 IKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIA 349
I + ++++ E +E+ + R + E E ++E+ + ++ A
Sbjct: 366 IAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELRE--QKEKSERAAFEELEKALSTA 423
Query: 350 VQLMHVRHEKEVLWQNRIFR-EKQHEERRLKDFQDALDREAALAKQAKIDF-----EEQF 403
+ R + + +I EK EE R+ +L +E + KQ +D EEQ
Sbjct: 424 QKTEEARRKLKAEMDEQIKTIEKTSEEERI-----SLQQELSRVKQEVVDVMKKSSEEQI 478
Query: 404 LKEKRFHDQIAVERAQARYEKHYSVCAEILDQI-VDLSTKVADY 446
K ++ H++ + Q +K + E +Q+ V L ++Y
Sbjct: 479 AKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEY 522
>gi|109134347 NY-REN-58 antigen [Homo sapiens]
Length = 701
Score = 52.0 bits (123), Expect = 1e-06
Identities = 78/398 (19%), Positives = 163/398 (40%), Gaps = 49/398 (12%)
Query: 116 EMQTMQRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAH-LH 174
E QT Q L L+ ++ + ++ + D M++ +K + ++ + L
Sbjct: 76 EKQTQQEKLQLLLEELRGE--------LVEKTKDLEEMKLQILTPQKLELLRAQIQQELE 127
Query: 175 FEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQ--------AAIIQIPKPASNRTL 226
ERF+ L EE + + N+ R K + A I+ K +
Sbjct: 128 TPMRERFRNLDEEVEKY---RAVYNKLRYEHTFLKSEFEHQKEEYARILDEGKIKYESEI 184
Query: 227 KALEAQKM-MKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYS 285
LE K ++ + D+ + K+ E L ++ + + + A + + N+ +
Sbjct: 185 ARLEEDKEELRNQLLNVDLTKDSKRVEQLAREKVYLCQKLKGLEAEVA-ELKAEKENSEA 243
Query: 286 DDEYIKKIQKR--LEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQ 343
E ++IQ R E A R +++ L + + E Q + + LIN+L + +
Sbjct: 244 QVENAQRIQVRQLAEMQATVRSLEAEKQSANLRAERLEKELQSSSEQNTFLINKLHKAER 303
Query: 344 QERRIAVQLMHVRHEKEV------LWQNRIFREKQHEERRLKDFQDALDREAALAKQAKI 397
+ ++ ++ ++H ++ L R E + E +++ D L + + K A +
Sbjct: 304 EINTLSSKVKELKHSNKLEITDIKLETARAKSELERERNKIQSELDGLQSDNEILK-AAV 362
Query: 398 DFEEQFLKEKRFHDQIAVERAQARYEKHYSVCAEILDQIVDLSTKVADYRMLTNNLIPYK 457
+ + L EK D+ + + QA E+ Y + D+ ++L ++AD + K
Sbjct: 363 EHHKVLLVEK---DRELIRKVQAAKEEGYQKLVVLQDEKLELENRLADLEKM-------K 412
Query: 458 LMHD-WKELFFNAKPIYEQASVKTLPANPSREQLTELE 494
+ HD W++ + K YE+ L A+ E++T E
Sbjct: 413 VEHDVWRQ---SEKDQYEE----KLRASQMAEEITRKE 443
Score = 38.9 bits (89), Expect = 0.011
Identities = 57/256 (22%), Positives = 114/256 (44%), Gaps = 43/256 (16%)
Query: 110 SGLTGVEMQTMQRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITY-RFQEKYKHVKE 168
SGLTG + + + L + RL R H + ++ ++ + R Q ++ ++
Sbjct: 22 SGLTGSQSEFQKMLIDERL----------RCEH---HKANYQTLKAEHTRLQNEHVKLQN 68
Query: 169 DLAHLHFEK---LERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRT 225
+L HL EK E+ Q L EE R +EK ++ +QI P
Sbjct: 69 ELKHLFNEKQTQQEKLQLLLEELRGELVEK-----------TKDLEEMKLQILTPQKLEL 117
Query: 226 LKALEAQKMMKKKKEA-EDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTY 284
L+A Q++ +E ++ +E++K+ A+ K L+ + + K+ + + +L+
Sbjct: 118 LRAQIQQELETPMRERFRNLDEEVEKYRAVYNK-LRYEHTFLKSEFEHQKEEYARILDE- 175
Query: 285 SDDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQ 344
+Y +I RLEED ++ L +QL+ + +++ R EQL + Q+
Sbjct: 176 GKIKYESEI-ARLEED-----------KEELRNQLLNVDLTKDSKRVEQLAREKVYLCQK 223
Query: 345 ERRIAVQLMHVRHEKE 360
+ + ++ ++ EKE
Sbjct: 224 LKGLEAEVAELKAEKE 239
>gi|109134355 NY-REN-58 antigen [Homo sapiens]
Length = 701
Score = 52.0 bits (123), Expect = 1e-06
Identities = 78/398 (19%), Positives = 163/398 (40%), Gaps = 49/398 (12%)
Query: 116 EMQTMQRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAH-LH 174
E QT Q L L+ ++ + ++ + D M++ +K + ++ + L
Sbjct: 76 EKQTQQEKLQLLLEELRGE--------LVEKTKDLEEMKLQILTPQKLELLRAQIQQELE 127
Query: 175 FEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQ--------AAIIQIPKPASNRTL 226
ERF+ L EE + + N+ R K + A I+ K +
Sbjct: 128 TPMRERFRNLDEEVEKY---RAVYNKLRYEHTFLKSEFEHQKEEYARILDEGKIKYESEI 184
Query: 227 KALEAQKM-MKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYS 285
LE K ++ + D+ + K+ E L ++ + + + A + + N+ +
Sbjct: 185 ARLEEDKEELRNQLLNVDLTKDSKRVEQLAREKVYLCQKLKGLEAEVA-ELKAEKENSEA 243
Query: 286 DDEYIKKIQKR--LEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQ 343
E ++IQ R E A R +++ L + + E Q + + LIN+L + +
Sbjct: 244 QVENAQRIQVRQLAEMQATVRSLEAEKQSANLRAERLEKELQSSSEQNTFLINKLHKAER 303
Query: 344 QERRIAVQLMHVRHEKEV------LWQNRIFREKQHEERRLKDFQDALDREAALAKQAKI 397
+ ++ ++ ++H ++ L R E + E +++ D L + + K A +
Sbjct: 304 EINTLSSKVKELKHSNKLEITDIKLETARAKSELERERNKIQSELDGLQSDNEILK-AAV 362
Query: 398 DFEEQFLKEKRFHDQIAVERAQARYEKHYSVCAEILDQIVDLSTKVADYRMLTNNLIPYK 457
+ + L EK D+ + + QA E+ Y + D+ ++L ++AD + K
Sbjct: 363 EHHKVLLVEK---DRELIRKVQAAKEEGYQKLVVLQDEKLELENRLADLEKM-------K 412
Query: 458 LMHD-WKELFFNAKPIYEQASVKTLPANPSREQLTELE 494
+ HD W++ + K YE+ L A+ E++T E
Sbjct: 413 VEHDVWRQ---SEKDQYEE----KLRASQMAEEITRKE 443
Score = 38.9 bits (89), Expect = 0.011
Identities = 57/256 (22%), Positives = 114/256 (44%), Gaps = 43/256 (16%)
Query: 110 SGLTGVEMQTMQRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITY-RFQEKYKHVKE 168
SGLTG + + + L + RL R H + ++ ++ + R Q ++ ++
Sbjct: 22 SGLTGSQSEFQKMLIDERL----------RCEH---HKANYQTLKAEHTRLQNEHVKLQN 68
Query: 169 DLAHLHFEK---LERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRT 225
+L HL EK E+ Q L EE R +EK ++ +QI P
Sbjct: 69 ELKHLFNEKQTQQEKLQLLLEELRGELVEK-----------TKDLEEMKLQILTPQKLEL 117
Query: 226 LKALEAQKMMKKKKEA-EDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTY 284
L+A Q++ +E ++ +E++K+ A+ K L+ + + K+ + + +L+
Sbjct: 118 LRAQIQQELETPMRERFRNLDEEVEKYRAVYNK-LRYEHTFLKSEFEHQKEEYARILDE- 175
Query: 285 SDDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQ 344
+Y +I RLEED ++ L +QL+ + +++ R EQL + Q+
Sbjct: 176 GKIKYESEI-ARLEED-----------KEELRNQLLNVDLTKDSKRVEQLAREKVYLCQK 223
Query: 345 ERRIAVQLMHVRHEKE 360
+ + ++ ++ EKE
Sbjct: 224 LKGLEAEVAELKAEKE 239
>gi|148612801 KIAA1009 protein [Homo sapiens]
Length = 1403
Score = 52.0 bits (123), Expect = 1e-06
Identities = 86/358 (24%), Positives = 148/358 (41%), Gaps = 52/358 (14%)
Query: 123 LTNLRLQNMKSDTFQERLRHMIPR----QTDFNLMR---------ITYRFQEKYKHVKED 169
L LR+ + D+ E ++ + + DF M+ I Y EK +K
Sbjct: 788 LAELRMAQKEKDSLLEDIKRLKQDKQALEVDFEKMKKERDQAKDQIAYVTGEKLYEIKI- 846
Query: 170 LAHLHFEKLERFQK----LKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRT 225
L H +++ R QK E Q D K L R NE + K++ I ++ + N +
Sbjct: 847 LEETHKQEISRLQKRLQWYAENQELLD--KDALRLREANEEIEKLKLEIEKLKAESGNPS 904
Query: 226 LKALEAQKMMKKKKEAE-----DVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDL 280
++ QK+ K K A+ D+ ++K+ E ++K+ A + AG T
Sbjct: 905 IR----QKIRLKDKAADAKKIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDTVDK- 959
Query: 281 LNTYSDDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEE--AYREEQLINRL 338
NT E+++K K+LE D +++ K+ + + Q + Q E ++EQL+
Sbjct: 960 -NTV---EFMEKRIKKLEADLEGKDEDAKKSLRTMEQQFQKMKIQYEQRLEQQEQLLACK 1015
Query: 339 MRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKID 398
+ Q R A+ EKE+ + I Q R L+ D L + A K D
Sbjct: 1016 LNQHDSPRIKAL-------EKEL---DDIKEAHQITVRNLEAEIDVLKHQNAELDVKKND 1065
Query: 399 FEEQFLKEKRFHDQIAVERAQARYEKHYSVCAEILDQIVDLSTKV----ADYRMLTNN 452
+++ + F Q+ A+A+ + A +I DLS V D RM+ +N
Sbjct: 1066 KDDEDFQSIEF--QVEQAHAKAKLVRLNEELAAKKREIQDLSKTVERLQKDRRMMLSN 1121
Score = 38.1 bits (87), Expect = 0.019
Identities = 58/247 (23%), Positives = 99/247 (40%), Gaps = 24/247 (9%)
Query: 194 EKQYLNRRRQNEIMAK---IQAAIIQIPKPASNRTLKALEAQKMMKKKKEAEDVADEIKK 250
EK+ L +R E K QA I QI S + K LE K+ + KK+ E ++ +
Sbjct: 610 EKKLLMFKRVQEAEDKWRGAQALIEQIKATFSEKE-KELE-NKLEELKKQQEKELFKLNQ 667
Query: 251 FEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQKRLEEDAFAREQREKR 310
+++ L + E +K D + E +K+IQK ++E + ++
Sbjct: 668 DNYILQAKLSSFEETNKKQRWLHFGEAADPVT----GEKLKQIQKEIQEQETLLQGYQQE 723
Query: 311 RRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQLMHVRHEKEVLWQ------ 364
+L + QE+ + E+ R+ +++Q L H+ L Q
Sbjct: 724 NERLYNQ---VKDLQEQNKKNEE---RMFKENQSLFSEVASLKEQMHKSRFLSQVVEDSE 777
Query: 365 ---NRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKEKRFHDQIAVERAQAR 421
N+ F + E R + +D+L + KQ K E F K K+ DQ + A
Sbjct: 778 PTRNQNFTDLLAELRMAQKEKDSLLEDIKRLKQDKQALEVDFEKMKKERDQAKDQIAYVT 837
Query: 422 YEKHYSV 428
EK Y +
Sbjct: 838 GEKLYEI 844
Score = 30.8 bits (68), Expect = 3.1
Identities = 56/261 (21%), Positives = 105/261 (40%), Gaps = 31/261 (11%)
Query: 160 QEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPK 219
++++ H E + EKL++ QK +EQ Q N R N++
Sbjct: 685 KQRWLHFGEAADPVTGEKLKQIQKEIQEQETLLQGYQQENERLYNQV------------- 731
Query: 220 PASNRTLKALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTD 279
+ L+ + + KE + + E+ + + K + + S T Q TD
Sbjct: 732 ----KDLQEQNKKNEERMFKENQSLFSEVASLKEQMHKS-RFLSQVVEDSEPTRNQNFTD 786
Query: 280 LL----NTYSDDEYIKKIQKRLEEDAFARE---QREKRRRKLLMDQLIAHEAQEEAYREE 332
LL + + + + KRL++D A E ++ K+ R DQ IA+ E+ Y +
Sbjct: 787 LLAELRMAQKEKDSLLEDIKRLKQDKQALEVDFEKMKKERDQAKDQ-IAYVTGEKLYEIK 845
Query: 333 QLINRLMRQSQQERRIAVQLMHVRHEKEVLWQNRI-FREKQHEERRLKDFQDALDREAAL 391
L Q+ R+ +L +E+L ++ + RE E +LK + L E+
Sbjct: 846 ILEE---THKQEISRLQKRLQWYAENQELLDKDALRLREANEEIEKLKLEIEKLKAESGN 902
Query: 392 AK-QAKIDFEEQFLKEKRFHD 411
+ KI +++ K+ D
Sbjct: 903 PSIRQKIRLKDKAADAKKIQD 923
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 51.2 bits (121), Expect = 2e-06
Identities = 65/275 (23%), Positives = 130/275 (47%), Gaps = 30/275 (10%)
Query: 115 VEMQTMQRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLH 174
VE Q ++L RL ++++D+ +E R + +Q R+T Q+ H++ H
Sbjct: 1399 VEQQNKRQLER-RLGDLQADS-EESQRAL--QQLKKKCQRLTAELQDTKLHLEGQQVRNH 1454
Query: 175 FEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKM 234
+L+++QR FD E + Q E K+Q +Q K +L+ Q++
Sbjct: 1455 --------ELEKKQRRFDSELSQAHEEAQRE---KLQREKLQREKDMLLAEAFSLK-QQL 1502
Query: 235 MKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQ 294
+K + ++ EA ++ D+ ++ES + SL + DL + +K +
Sbjct: 1503 EEKDMDIAGFTQKVVSLEAELQ-DISSQESKDEASLAKVKKQLRDL------EAKVKDQE 1555
Query: 295 KRLEEDAFAREQRE--KRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQL 352
+ L+E A + E K R ++ M+++ ++E R+E++ RQS Q++ ++
Sbjct: 1556 EELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEA--RQSCQKK---LKQ 1610
Query: 353 MHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDR 387
M V+ E+E + ++ REK+ E +L D ++R
Sbjct: 1611 MEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNR 1645
Score = 38.9 bits (89), Expect = 0.011
Identities = 43/190 (22%), Positives = 84/190 (44%), Gaps = 22/190 (11%)
Query: 166 VKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRT 225
++E L+ L EK E +L+E+Q NE+M K +AA+ Q + +
Sbjct: 1730 LEEQLSRLQREKNEIQNRLEEDQE------------DMNELMKKHKAAVAQASRDLAQIN 1777
Query: 226 LKALEAQKMMKKKKEAEDVADEIKK-----FEALIKKDLQAKESASKTSLDTAGQ-TTTD 279
+ ++ K+K+E ++ ++ ++++ K L +++ A L+T + T
Sbjct: 1778 DLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQ 1837
Query: 280 LLNTYSDDEYIKKIQKRLEED---AFAREQREKRRRKLLMDQL-IAHEAQEEAYREEQLI 335
+ S +K+ ++L E+ A E REK + K L QL E E R+E
Sbjct: 1838 VKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEA 1897
Query: 336 NRLMRQSQQE 345
+R + + +
Sbjct: 1898 SRKKHELEMD 1907
Score = 33.9 bits (76), Expect = 0.36
Identities = 59/308 (19%), Positives = 132/308 (42%), Gaps = 42/308 (13%)
Query: 179 ERFQKLKEEQRCFDIEKQYLNRRRQNEIMAK--IQAAIIQIPKPASN------------R 224
E ++L+ E+ +++ QY ++Q E+M ++A +I+ + +
Sbjct: 1315 ETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLK 1374
Query: 225 TLKALEAQKMMKKK--KEAEDVADEIKKFEALIKK---DLQAKESASKTSLDTAGQTTTD 279
+A+ KK+ +E ED + ++ + +++ DLQA S+ +L +
Sbjct: 1375 YERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQR 1434
Query: 280 LLNTYSD-----------DEYIKKIQKRLEED---AFAREQREKRRRKLLM---DQLIAH 322
L D + ++K Q+R + + A QREK +R+ L D L+A
Sbjct: 1435 LTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAE 1494
Query: 323 EAQEEAYREEQLINRLMRQSQQERRIAVQLMHV--RHEKEVLWQNRIFREKQHEERRLKD 380
+ EE+ ++ + +Q+ + +L + + K+ ++ ++ + E ++KD
Sbjct: 1495 AFSLKQQLEEKDMD-IAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKD 1553
Query: 381 FQDALDREAA---LAKQAKIDFEEQFLKEKRFHDQIAVERAQARYEKHYSVCAEILDQIV 437
++ LD +A + +QAK+ E + + ++ H + R + E S ++ V
Sbjct: 1554 QEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEV 1613
Query: 438 DLSTKVAD 445
L + D
Sbjct: 1614 QLEEEYED 1621
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 51.2 bits (121), Expect = 2e-06
Identities = 65/275 (23%), Positives = 130/275 (47%), Gaps = 30/275 (10%)
Query: 115 VEMQTMQRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLH 174
VE Q ++L RL ++++D+ +E R + +Q R+T Q+ H++ H
Sbjct: 1399 VEQQNKRQLER-RLGDLQADS-EESQRAL--QQLKKKCQRLTAELQDTKLHLEGQQVRNH 1454
Query: 175 FEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKM 234
+L+++QR FD E + Q E K+Q +Q K +L+ Q++
Sbjct: 1455 --------ELEKKQRRFDSELSQAHEEAQRE---KLQREKLQREKDMLLAEAFSLK-QQL 1502
Query: 235 MKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQ 294
+K + ++ EA ++ D+ ++ES + SL + DL + +K +
Sbjct: 1503 EEKDMDIAGFTQKVVSLEAELQ-DISSQESKDEASLAKVKKQLRDL------EAKVKDQE 1555
Query: 295 KRLEEDAFAREQRE--KRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQL 352
+ L+E A + E K R ++ M+++ ++E R+E++ RQS Q++ ++
Sbjct: 1556 EELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEA--RQSCQKK---LKQ 1610
Query: 353 MHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDR 387
M V+ E+E + ++ REK+ E +L D ++R
Sbjct: 1611 MEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNR 1645
Score = 40.4 bits (93), Expect = 0.004
Identities = 62/279 (22%), Positives = 117/279 (41%), Gaps = 52/279 (18%)
Query: 166 VKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRT 225
++E L+ L EK E +L+E+Q NE+M K +AA+ Q + +
Sbjct: 1730 LEEQLSRLQREKNEIQNRLEEDQE------------DMNELMKKHKAAVAQASRDLAQ-- 1775
Query: 226 LKALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYS 285
+ L+AQ K+ K++LQ K A ++ ++ Q+ D
Sbjct: 1776 INDLQAQLEEANKE----------------KQELQEKLQALQSQVEFLEQSMVDKSLVSR 1819
Query: 286 DDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYRE-EQLINRLMRQSQQ 344
+ I++++ RLE E+ + +R + L +L E E+ E +Q I R+ +Q
Sbjct: 1820 QEAKIRELETRLE-----FERTQVKRLESLASRL--KENMEKLTEERDQRIAAENREKEQ 1872
Query: 345 ERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFL 404
+R+ QL + E + R++ R+ + + L+ A + + D + F
Sbjct: 1873 NKRLQRQLRDTKEE-----MGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAF- 1926
Query: 405 KEKRFHD-QIAVERAQARYEKHYSVCAEILDQIVDLSTK 442
KR D Q A+E E ++++ + D+ TK
Sbjct: 1927 --KRIGDLQAAIEDEMESDENE-----DLINSLQDMVTK 1958
Score = 33.9 bits (76), Expect = 0.36
Identities = 59/308 (19%), Positives = 132/308 (42%), Gaps = 42/308 (13%)
Query: 179 ERFQKLKEEQRCFDIEKQYLNRRRQNEIMAK--IQAAIIQIPKPASN------------R 224
E ++L+ E+ +++ QY ++Q E+M ++A +I+ + +
Sbjct: 1315 ETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLK 1374
Query: 225 TLKALEAQKMMKKK--KEAEDVADEIKKFEALIKK---DLQAKESASKTSLDTAGQTTTD 279
+A+ KK+ +E ED + ++ + +++ DLQA S+ +L +
Sbjct: 1375 YERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQR 1434
Query: 280 LLNTYSD-----------DEYIKKIQKRLEED---AFAREQREKRRRKLLM---DQLIAH 322
L D + ++K Q+R + + A QREK +R+ L D L+A
Sbjct: 1435 LTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAE 1494
Query: 323 EAQEEAYREEQLINRLMRQSQQERRIAVQLMHV--RHEKEVLWQNRIFREKQHEERRLKD 380
+ EE+ ++ + +Q+ + +L + + K+ ++ ++ + E ++KD
Sbjct: 1495 AFSLKQQLEEKDMD-IAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKD 1553
Query: 381 FQDALDREAA---LAKQAKIDFEEQFLKEKRFHDQIAVERAQARYEKHYSVCAEILDQIV 437
++ LD +A + +QAK+ E + + ++ H + R + E S ++ V
Sbjct: 1554 QEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEV 1613
Query: 438 DLSTKVAD 445
L + D
Sbjct: 1614 QLEEEYED 1621
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 50.8 bits (120), Expect = 3e-06
Identities = 47/201 (23%), Positives = 98/201 (48%), Gaps = 24/201 (11%)
Query: 228 ALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDD 287
ALE + ++K K A+ + E ++ E K++ + ++ + + ++L ++
Sbjct: 716 ALEQLQQLEKAKAAK-LEQERREAEMRAKREEEERKRQEELR-----RQQEEILRRQQEE 769
Query: 288 EYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQ--LINRL--MRQSQ 343
E +KR EE+ AR ++E+ R+ ++ +EE R++Q + RL R+ +
Sbjct: 770 E-----RKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREE 824
Query: 344 QERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQF 403
+ERR +L+ + E+ W RE++ +RRL++ + ++ EA A++ EE+
Sbjct: 825 EERRKQEELLRKQEEEAAKWA----REEEEAQRRLEENRLRMEEEA-----ARLRHEEEE 875
Query: 404 LKEKRFHDQIAVERAQARYEK 424
K K Q E + R ++
Sbjct: 876 RKRKELEVQRQKELMRQRQQQ 896
Score = 44.7 bits (104), Expect = 2e-04
Identities = 50/259 (19%), Positives = 118/259 (45%), Gaps = 37/259 (14%)
Query: 160 QEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPK 219
+E+ + +E+L E L R Q+ + ++R E++ L RR+Q E + + + I + +
Sbjct: 745 EEEERKRQEELRRQQEEILRRQQEEERKRR----EEEELARRKQEEALRRQREQEIALRR 800
Query: 220 PASNRTLKALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTD 279
+ + ++ +++ +E +E +K E L++K +E A+K + +
Sbjct: 801 QREEEERQ--QQEEALRRLEERRREEEERRKQEELLRKQ---EEEAAKWARE-------- 847
Query: 280 LLNTYSDDEYIKKIQK---RLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLIN 336
++E +++++ R+EE+A E+ R++ ++ E + ++++ +
Sbjct: 848 ------EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALR 901
Query: 337 RLMRQSQQERRIAVQL-----------MHVRHEKEVLWQNRIFREKQHEERRLKDFQDAL 385
RL +Q QQ++ ++L + L I + ++ ER+L++ Q
Sbjct: 902 RLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQ 961
Query: 386 DREAALAKQAKIDFEEQFL 404
RE A Q + ++Q L
Sbjct: 962 QRELMKALQQQQQQQQQKL 980
Score = 35.4 bits (80), Expect = 0.13
Identities = 45/247 (18%), Positives = 116/247 (46%), Gaps = 12/247 (4%)
Query: 170 LAHLHFEKLERFQKLKEEQRCFDIE-KQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKA 228
+ L E+L R Q+L + ++ +Q+L +++ +++A+ Q A + + L
Sbjct: 596 MGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALL-- 653
Query: 229 LEAQKMMKKKKEAEDVADEIKKFEALIKKDL--QAKESASKTSLDTAGQTTTDLLNTYSD 286
L+ + +K + +++ + + ++ + + +AS+ ++ G L+T +
Sbjct: 654 LQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTP 713
Query: 287 DEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQER 346
++++Q+ + A EQ + + + QEE R+++ I R ++ +++R
Sbjct: 714 GPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKR 773
Query: 347 RIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKE 406
R +L + E+ + Q RE++ RR ++ ++ +E AL + + EE+ E
Sbjct: 774 REEEELARRKQEEALRRQ----REQEIALRRQREEEERQQQEEALRRLEERRREEE---E 826
Query: 407 KRFHDQI 413
+R +++
Sbjct: 827 RRKQEEL 833
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 50.8 bits (120), Expect = 3e-06
Identities = 47/201 (23%), Positives = 98/201 (48%), Gaps = 24/201 (11%)
Query: 228 ALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDD 287
ALE + ++K K A+ + E ++ E K++ + ++ + + ++L ++
Sbjct: 743 ALEQLQQLEKAKAAK-LEQERREAEMRAKREEEERKRQEELR-----RQQEEILRRQQEE 796
Query: 288 EYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQ--LINRL--MRQSQ 343
E +KR EE+ AR ++E+ R+ ++ +EE R++Q + RL R+ +
Sbjct: 797 E-----RKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREE 851
Query: 344 QERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQF 403
+ERR +L+ + E+ W RE++ +RRL++ + ++ EA A++ EE+
Sbjct: 852 EERRKQEELLRKQEEEAAKWA----REEEEAQRRLEENRLRMEEEA-----ARLRHEEEE 902
Query: 404 LKEKRFHDQIAVERAQARYEK 424
K K Q E + R ++
Sbjct: 903 RKRKELEVQRQKELMRQRQQQ 923
Score = 44.7 bits (104), Expect = 2e-04
Identities = 50/259 (19%), Positives = 118/259 (45%), Gaps = 37/259 (14%)
Query: 160 QEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPK 219
+E+ + +E+L E L R Q+ + ++R E++ L RR+Q E + + + I + +
Sbjct: 772 EEEERKRQEELRRQQEEILRRQQEEERKRR----EEEELARRKQEEALRRQREQEIALRR 827
Query: 220 PASNRTLKALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTD 279
+ + ++ +++ +E +E +K E L++K +E A+K + +
Sbjct: 828 QREEEERQ--QQEEALRRLEERRREEEERRKQEELLRKQ---EEEAAKWARE-------- 874
Query: 280 LLNTYSDDEYIKKIQK---RLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLIN 336
++E +++++ R+EE+A E+ R++ ++ E + ++++ +
Sbjct: 875 ------EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALR 928
Query: 337 RLMRQSQQERRIAVQL-----------MHVRHEKEVLWQNRIFREKQHEERRLKDFQDAL 385
RL +Q QQ++ ++L + L I + ++ ER+L++ Q
Sbjct: 929 RLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQ 988
Query: 386 DREAALAKQAKIDFEEQFL 404
RE A Q + ++Q L
Sbjct: 989 QRELMKALQQQQQQQQQKL 1007
Score = 35.4 bits (80), Expect = 0.13
Identities = 45/247 (18%), Positives = 116/247 (46%), Gaps = 12/247 (4%)
Query: 170 LAHLHFEKLERFQKLKEEQRCFDIE-KQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKA 228
+ L E+L R Q+L + ++ +Q+L +++ +++A+ Q A + + L
Sbjct: 623 MGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALL-- 680
Query: 229 LEAQKMMKKKKEAEDVADEIKKFEALIKKDL--QAKESASKTSLDTAGQTTTDLLNTYSD 286
L+ + +K + +++ + + ++ + + +AS+ ++ G L+T +
Sbjct: 681 LQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTP 740
Query: 287 DEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQER 346
++++Q+ + A EQ + + + QEE R+++ I R ++ +++R
Sbjct: 741 GPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKR 800
Query: 347 RIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKE 406
R +L + E+ + Q RE++ RR ++ ++ +E AL + + EE+ E
Sbjct: 801 REEEELARRKQEEALRRQ----REQEIALRRQREEEERQQQEEALRRLEERRREEE---E 853
Query: 407 KRFHDQI 413
+R +++
Sbjct: 854 RRKQEEL 860
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 50.8 bits (120), Expect = 3e-06
Identities = 47/201 (23%), Positives = 98/201 (48%), Gaps = 24/201 (11%)
Query: 228 ALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDD 287
ALE + ++K K A+ + E ++ E K++ + ++ + + ++L ++
Sbjct: 722 ALEQLQQLEKAKAAK-LEQERREAEMRAKREEEERKRQEELR-----RQQEEILRRQQEE 775
Query: 288 EYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQ--LINRL--MRQSQ 343
E +KR EE+ AR ++E+ R+ ++ +EE R++Q + RL R+ +
Sbjct: 776 E-----RKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREE 830
Query: 344 QERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQF 403
+ERR +L+ + E+ W RE++ +RRL++ + ++ EA A++ EE+
Sbjct: 831 EERRKQEELLRKQEEEAAKWA----REEEEAQRRLEENRLRMEEEA-----ARLRHEEEE 881
Query: 404 LKEKRFHDQIAVERAQARYEK 424
K K Q E + R ++
Sbjct: 882 RKRKELEVQRQKELMRQRQQQ 902
Score = 44.7 bits (104), Expect = 2e-04
Identities = 50/259 (19%), Positives = 118/259 (45%), Gaps = 37/259 (14%)
Query: 160 QEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPK 219
+E+ + +E+L E L R Q+ + ++R E++ L RR+Q E + + + I + +
Sbjct: 751 EEEERKRQEELRRQQEEILRRQQEEERKRR----EEEELARRKQEEALRRQREQEIALRR 806
Query: 220 PASNRTLKALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTD 279
+ + ++ +++ +E +E +K E L++K +E A+K + +
Sbjct: 807 QREEEERQ--QQEEALRRLEERRREEEERRKQEELLRKQ---EEEAAKWARE-------- 853
Query: 280 LLNTYSDDEYIKKIQK---RLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLIN 336
++E +++++ R+EE+A E+ R++ ++ E + ++++ +
Sbjct: 854 ------EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALR 907
Query: 337 RLMRQSQQERRIAVQL-----------MHVRHEKEVLWQNRIFREKQHEERRLKDFQDAL 385
RL +Q QQ++ ++L + L I + ++ ER+L++ Q
Sbjct: 908 RLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQ 967
Query: 386 DREAALAKQAKIDFEEQFL 404
RE A Q + ++Q L
Sbjct: 968 QRELMKALQQQQQQQQQKL 986
Score = 35.4 bits (80), Expect = 0.13
Identities = 45/247 (18%), Positives = 116/247 (46%), Gaps = 12/247 (4%)
Query: 170 LAHLHFEKLERFQKLKEEQRCFDIE-KQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKA 228
+ L E+L R Q+L + ++ +Q+L +++ +++A+ Q A + + L
Sbjct: 602 MGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALL-- 659
Query: 229 LEAQKMMKKKKEAEDVADEIKKFEALIKKDL--QAKESASKTSLDTAGQTTTDLLNTYSD 286
L+ + +K + +++ + + ++ + + +AS+ ++ G L+T +
Sbjct: 660 LQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTP 719
Query: 287 DEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQER 346
++++Q+ + A EQ + + + QEE R+++ I R ++ +++R
Sbjct: 720 GPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKR 779
Query: 347 RIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKE 406
R +L + E+ + Q RE++ RR ++ ++ +E AL + + EE+ E
Sbjct: 780 REEEELARRKQEEALRRQ----REQEIALRRQREEEERQQQEEALRRLEERRREEE---E 832
Query: 407 KRFHDQI 413
+R +++
Sbjct: 833 RRKQEEL 839
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 50.8 bits (120), Expect = 3e-06
Identities = 47/201 (23%), Positives = 98/201 (48%), Gaps = 24/201 (11%)
Query: 228 ALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDD 287
ALE + ++K K A+ + E ++ E K++ + ++ + + ++L ++
Sbjct: 722 ALEQLQQLEKAKAAK-LEQERREAEMRAKREEEERKRQEELR-----RQQEEILRRQQEE 775
Query: 288 EYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQ--LINRL--MRQSQ 343
E +KR EE+ AR ++E+ R+ ++ +EE R++Q + RL R+ +
Sbjct: 776 E-----RKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREE 830
Query: 344 QERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQF 403
+ERR +L+ + E+ W RE++ +RRL++ + ++ EA A++ EE+
Sbjct: 831 EERRKQEELLRKQEEEAAKWA----REEEEAQRRLEENRLRMEEEA-----ARLRHEEEE 881
Query: 404 LKEKRFHDQIAVERAQARYEK 424
K K Q E + R ++
Sbjct: 882 RKRKELEVQRQKELMRQRQQQ 902
Score = 44.7 bits (104), Expect = 2e-04
Identities = 50/259 (19%), Positives = 118/259 (45%), Gaps = 37/259 (14%)
Query: 160 QEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPK 219
+E+ + +E+L E L R Q+ + ++R E++ L RR+Q E + + + I + +
Sbjct: 751 EEEERKRQEELRRQQEEILRRQQEEERKRR----EEEELARRKQEEALRRQREQEIALRR 806
Query: 220 PASNRTLKALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTD 279
+ + ++ +++ +E +E +K E L++K +E A+K + +
Sbjct: 807 QREEEERQ--QQEEALRRLEERRREEEERRKQEELLRKQ---EEEAAKWARE-------- 853
Query: 280 LLNTYSDDEYIKKIQK---RLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLIN 336
++E +++++ R+EE+A E+ R++ ++ E + ++++ +
Sbjct: 854 ------EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALR 907
Query: 337 RLMRQSQQERRIAVQL-----------MHVRHEKEVLWQNRIFREKQHEERRLKDFQDAL 385
RL +Q QQ++ ++L + L I + ++ ER+L++ Q
Sbjct: 908 RLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQ 967
Query: 386 DREAALAKQAKIDFEEQFL 404
RE A Q + ++Q L
Sbjct: 968 QRELMKALQQQQQQQQQKL 986
Score = 35.4 bits (80), Expect = 0.13
Identities = 45/247 (18%), Positives = 116/247 (46%), Gaps = 12/247 (4%)
Query: 170 LAHLHFEKLERFQKLKEEQRCFDIE-KQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKA 228
+ L E+L R Q+L + ++ +Q+L +++ +++A+ Q A + + L
Sbjct: 602 MGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALL-- 659
Query: 229 LEAQKMMKKKKEAEDVADEIKKFEALIKKDL--QAKESASKTSLDTAGQTTTDLLNTYSD 286
L+ + +K + +++ + + ++ + + +AS+ ++ G L+T +
Sbjct: 660 LQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTP 719
Query: 287 DEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQER 346
++++Q+ + A EQ + + + QEE R+++ I R ++ +++R
Sbjct: 720 GPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKR 779
Query: 347 RIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKE 406
R +L + E+ + Q RE++ RR ++ ++ +E AL + + EE+ E
Sbjct: 780 REEEELARRKQEEALRRQ----REQEIALRRQREEEERQQQEEALRRLEERRREEE---E 832
Query: 407 KRFHDQI 413
+R +++
Sbjct: 833 RRKQEEL 839
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 50.8 bits (120), Expect = 3e-06
Identities = 48/220 (21%), Positives = 100/220 (45%), Gaps = 19/220 (8%)
Query: 291 KKIQKRLEEDAFAREQREKR---RRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERR 347
K+ Q++ E + EQ+ + + LL +QL +A+ E Y E + + + +QE
Sbjct: 865 KERQQKAENELKELEQKHSQLTEEKNLLQEQL---QAETELYAEAEEMRVRLAAKKQELE 921
Query: 348 IAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKEK 407
+ M R E+E ++ E++ +++ D ++ L+ E A ++ +++ K K
Sbjct: 922 EILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIK 981
Query: 408 RFHDQIAV-ERAQARYEKHYSVCAEILDQIVDLSTKVADYRMLTNNLIPYKLMHDWKELF 466
+ D+I V + + K + E +I DL+T +A+ NL K H+
Sbjct: 982 KLEDEILVMDDQNNKLSKERKLLEE---RISDLTTNLAEEEEKAKNLTKLKNKHE----- 1033
Query: 467 FNAKPIYEQASVKTLPANPSREQLTELEKRDLLDTNDYEE 506
+ + V+ SR++L +L+++ D +D+ E
Sbjct: 1034 ----SMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE 1069
Score = 50.4 bits (119), Expect = 4e-06
Identities = 64/291 (21%), Positives = 138/291 (47%), Gaps = 24/291 (8%)
Query: 153 MRITYRFQEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQA 212
+R+ + QE + + E A L E+ +R Q+L+ E++ + L + + E A+ +
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEE-DRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK- 968
Query: 213 AIIQIPKPASNRTLKALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDT 272
+Q+ K + +K LE + ++ +D +++ K L+++ + + + + +
Sbjct: 969 --LQLEKVTAEAKIKKLEDEILVM-----DDQNNKLSKERKLLEERI-SDLTTNLAEEEE 1020
Query: 273 AGQTTTDLLNTYSDDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREE 332
+ T L N + + I +++ RL+++ +R++ EK +RKL D HE + A +
Sbjct: 1021 KAKNLTKLKNKH--ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE--QIADLQA 1076
Query: 333 QLINRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAAL- 391
Q+ M+ +++E + L R + E+ +N ++ + E + D Q+ LD E A
Sbjct: 1077 QIAELKMQLAKKEEELQAAL--ARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAAR 1134
Query: 392 --AKQAKIDFEEQF--LK---EKRFHDQIAVERAQARYEKHYSVCAEILDQ 435
A++ K D E+ LK E + +A+ E+ +V + LD+
Sbjct: 1135 NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1185
Score = 43.1 bits (100), Expect = 6e-04
Identities = 73/346 (21%), Positives = 151/346 (43%), Gaps = 39/346 (11%)
Query: 116 EMQTMQRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLHF 175
E++ +R +++ MK+ E L + D L R+ Q + DL
Sbjct: 1529 ELEKSKRALETQMEEMKTQL--EELEDELQATEDAKL-RLEVNMQALKGQFERDLQARDE 1585
Query: 176 EKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMA----KIQAAIIQIPKPASNRTLKALEA 231
+ E+ ++L+ + ++ E + + R+Q + A K++ + + A + EA
Sbjct: 1586 QNEEKRRQLQRQLHEYETELE--DERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEA 1643
Query: 232 QKMMKK-KKEAEDVADEIKKFEALIKKD---LQAKESASKTSLDTAGQTTTDLLNTYSDD 287
K ++K + + +D E++ +A +D AKE+ K A DL+ D
Sbjct: 1644 IKQLRKLQAQMKDFQRELE--DARASRDEIFATAKENEKK-----AKSLEADLMQLQEDL 1696
Query: 288 EYIKKIQKR--LEEDAFARE-----------QREKRRRKLLMDQLIAHEAQEEAYREEQL 334
++ +K+ LE++ A E Q EKRR + + QL E +EE E +
Sbjct: 1697 AAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQL-EEELEEEQGNMEAM 1755
Query: 335 INRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERR--LKDFQDALD---REA 389
+R+ + +QQ +++ +L R + R E+Q++E R L + + A+ +
Sbjct: 1756 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST 1815
Query: 390 ALAKQAKIDFEEQFLKEKRFHDQIAVERAQARYEKHYSVCAEILDQ 435
A +AKI E+ ++++ Q A + + + +K + ++ D+
Sbjct: 1816 IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDE 1861
Score = 40.4 bits (93), Expect = 0.004
Identities = 56/276 (20%), Positives = 120/276 (43%), Gaps = 24/276 (8%)
Query: 176 EKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMM 235
+K +F +L E++ +I +Y + R + E A+ + A L+A E +
Sbjct: 1448 KKQRKFDQLLAEEK--NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERT 1505
Query: 236 KK--KKEAEDVA---DEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEY- 289
K K E ED+ D++ K ++K +A E+ + + T + D L D +
Sbjct: 1506 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME-EMKTQLEELEDELQATEDAKLR 1564
Query: 290 ----IKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQE 345
++ ++ + E D AR+++ + +R+ L QL +E + E R+++ L ++++
Sbjct: 1565 LEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQR---ALAAAAKKK 1621
Query: 346 RRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLK 405
++ + ++ + + + ++ + + ++KDFQ L+ A + +E K
Sbjct: 1622 LEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKK 1681
Query: 406 EKRF--------HDQIAVERAQARYEKHYSVCAEIL 433
K D A ERA+ + + AE L
Sbjct: 1682 AKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL 1717
Score = 40.0 bits (92), Expect = 0.005
Identities = 75/375 (20%), Positives = 153/375 (40%), Gaps = 53/375 (14%)
Query: 126 LRLQNMKSDTFQERLRHMIPRQTDFN--LMRITYRFQEKYKHVKEDLAHLHFEKLERFQK 183
L+L+ + ++ ++L I D N L + +E+ + +LA EK + K
Sbjct: 969 LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE-EKAKNLTK 1027
Query: 184 LKEEQRCF------DIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMMKK 237
LK + ++K+ +R+ ++ K++ + ++ + E + + K
Sbjct: 1028 LKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK 1087
Query: 238 KKEAEDVA-----DEIKKFEALIKK---------DLQAKESASKTSLDTAGQTTTDLLNT 283
K+E A DEI + +KK DLQ + + + + A + DL
Sbjct: 1088 KEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDL--- 1144
Query: 284 YSDDEYIK-KIQKRLEEDAFAREQREKRR------RKLLMDQLIAHEAQEEAYREE--QL 334
+ E +K +++ L+ A +E R KR +K L ++ +HEAQ + R++ Q
Sbjct: 1145 GEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA 1204
Query: 335 INRLMRQSQQERRIAVQL-----------MHVRHEKEVLWQNRIFREKQHEERRLKDFQD 383
+ L Q +Q +R L + E VL Q + +E +H++++L+
Sbjct: 1205 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAK--QEVEHKKKKLEAQVQ 1262
Query: 384 ALDREAALAKQAKIDFEEQFLKEKRFHDQIAVERAQARYEKHYSVCAEILDQIVDLSTKV 443
L + + ++A+ + L +K Q VE + ++ + LS+++
Sbjct: 1263 ELQSKCSDGERARAE-----LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQL 1317
Query: 444 ADYRMLTNNLIPYKL 458
D + L KL
Sbjct: 1318 QDTQELLQEETRQKL 1332
Score = 30.0 bits (66), Expect = 5.3
Identities = 34/166 (20%), Positives = 71/166 (42%), Gaps = 8/166 (4%)
Query: 179 ERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMMKKK 238
ER K E +E+Q R + + +++ A+ K T+ ALEA+ ++
Sbjct: 1776 ERSTAQKNESARQQLERQNKELRSK---LHEMEGAV----KSKFKSTIAALEAKIAQLEE 1828
Query: 239 KEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQKRLE 298
+ ++ ++ ++L +KD + KE + D + +K+++++LE
Sbjct: 1829 QVEQEAREKQAATKSLKQKDKKLKEILLQVE-DERKMAEQYKEQAEKGNARVKQLKRQLE 1887
Query: 299 EDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQ 344
E ++ RRKL + A E+ E RE + +R+ +
Sbjct: 1888 EAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNE 1933
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 50.8 bits (120), Expect = 3e-06
Identities = 48/220 (21%), Positives = 100/220 (45%), Gaps = 19/220 (8%)
Query: 291 KKIQKRLEEDAFAREQREKR---RRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERR 347
K+ Q++ E + EQ+ + + LL +QL +A+ E Y E + + + +QE
Sbjct: 872 KERQQKAENELKELEQKHSQLTEEKNLLQEQL---QAETELYAEAEEMRVRLAAKKQELE 928
Query: 348 IAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKEK 407
+ M R E+E ++ E++ +++ D ++ L+ E A ++ +++ K K
Sbjct: 929 EILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIK 988
Query: 408 RFHDQIAV-ERAQARYEKHYSVCAEILDQIVDLSTKVADYRMLTNNLIPYKLMHDWKELF 466
+ D+I V + + K + E +I DL+T +A+ NL K H+
Sbjct: 989 KLEDEILVMDDQNNKLSKERKLLEE---RISDLTTNLAEEEEKAKNLTKLKNKHE----- 1040
Query: 467 FNAKPIYEQASVKTLPANPSREQLTELEKRDLLDTNDYEE 506
+ + V+ SR++L +L+++ D +D+ E
Sbjct: 1041 ----SMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE 1076
Score = 50.4 bits (119), Expect = 4e-06
Identities = 64/291 (21%), Positives = 138/291 (47%), Gaps = 24/291 (8%)
Query: 153 MRITYRFQEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQA 212
+R+ + QE + + E A L E+ +R Q+L+ E++ + L + + E A+ +
Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEE-DRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK- 975
Query: 213 AIIQIPKPASNRTLKALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDT 272
+Q+ K + +K LE + ++ +D +++ K L+++ + + + + +
Sbjct: 976 --LQLEKVTAEAKIKKLEDEILVM-----DDQNNKLSKERKLLEERI-SDLTTNLAEEEE 1027
Query: 273 AGQTTTDLLNTYSDDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREE 332
+ T L N + + I +++ RL+++ +R++ EK +RKL D HE + A +
Sbjct: 1028 KAKNLTKLKNKH--ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE--QIADLQA 1083
Query: 333 QLINRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAAL- 391
Q+ M+ +++E + L R + E+ +N ++ + E + D Q+ LD E A
Sbjct: 1084 QIAELKMQLAKKEEELQAAL--ARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAAR 1141
Query: 392 --AKQAKIDFEEQF--LK---EKRFHDQIAVERAQARYEKHYSVCAEILDQ 435
A++ K D E+ LK E + +A+ E+ +V + LD+
Sbjct: 1142 NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1192
Score = 43.1 bits (100), Expect = 6e-04
Identities = 73/346 (21%), Positives = 151/346 (43%), Gaps = 39/346 (11%)
Query: 116 EMQTMQRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLHF 175
E++ +R +++ MK+ E L + D L R+ Q + DL
Sbjct: 1536 ELEKSKRALETQMEEMKTQL--EELEDELQATEDAKL-RLEVNMQALKGQFERDLQARDE 1592
Query: 176 EKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMA----KIQAAIIQIPKPASNRTLKALEA 231
+ E+ ++L+ + ++ E + + R+Q + A K++ + + A + EA
Sbjct: 1593 QNEEKRRQLQRQLHEYETELE--DERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEA 1650
Query: 232 QKMMKK-KKEAEDVADEIKKFEALIKKD---LQAKESASKTSLDTAGQTTTDLLNTYSDD 287
K ++K + + +D E++ +A +D AKE+ K A DL+ D
Sbjct: 1651 IKQLRKLQAQMKDFQRELE--DARASRDEIFATAKENEKK-----AKSLEADLMQLQEDL 1703
Query: 288 EYIKKIQKR--LEEDAFARE-----------QREKRRRKLLMDQLIAHEAQEEAYREEQL 334
++ +K+ LE++ A E Q EKRR + + QL E +EE E +
Sbjct: 1704 AAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQL-EEELEEEQGNMEAM 1762
Query: 335 INRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERR--LKDFQDALD---REA 389
+R+ + +QQ +++ +L R + R E+Q++E R L + + A+ +
Sbjct: 1763 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST 1822
Query: 390 ALAKQAKIDFEEQFLKEKRFHDQIAVERAQARYEKHYSVCAEILDQ 435
A +AKI E+ ++++ Q A + + + +K + ++ D+
Sbjct: 1823 IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDE 1868
Score = 40.4 bits (93), Expect = 0.004
Identities = 56/276 (20%), Positives = 120/276 (43%), Gaps = 24/276 (8%)
Query: 176 EKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMM 235
+K +F +L E++ +I +Y + R + E A+ + A L+A E +
Sbjct: 1455 KKQRKFDQLLAEEK--NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERT 1512
Query: 236 KK--KKEAEDVA---DEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEY- 289
K K E ED+ D++ K ++K +A E+ + + T + D L D +
Sbjct: 1513 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME-EMKTQLEELEDELQATEDAKLR 1571
Query: 290 ----IKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQE 345
++ ++ + E D AR+++ + +R+ L QL +E + E R+++ L ++++
Sbjct: 1572 LEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQR---ALAAAAKKK 1628
Query: 346 RRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLK 405
++ + ++ + + + ++ + + ++KDFQ L+ A + +E K
Sbjct: 1629 LEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKK 1688
Query: 406 EKRF--------HDQIAVERAQARYEKHYSVCAEIL 433
K D A ERA+ + + AE L
Sbjct: 1689 AKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL 1724
Score = 40.0 bits (92), Expect = 0.005
Identities = 75/375 (20%), Positives = 153/375 (40%), Gaps = 53/375 (14%)
Query: 126 LRLQNMKSDTFQERLRHMIPRQTDFN--LMRITYRFQEKYKHVKEDLAHLHFEKLERFQK 183
L+L+ + ++ ++L I D N L + +E+ + +LA EK + K
Sbjct: 976 LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE-EKAKNLTK 1034
Query: 184 LKEEQRCF------DIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMMKK 237
LK + ++K+ +R+ ++ K++ + ++ + E + + K
Sbjct: 1035 LKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK 1094
Query: 238 KKEAEDVA-----DEIKKFEALIKK---------DLQAKESASKTSLDTAGQTTTDLLNT 283
K+E A DEI + +KK DLQ + + + + A + DL
Sbjct: 1095 KEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDL--- 1151
Query: 284 YSDDEYIK-KIQKRLEEDAFAREQREKRR------RKLLMDQLIAHEAQEEAYREE--QL 334
+ E +K +++ L+ A +E R KR +K L ++ +HEAQ + R++ Q
Sbjct: 1152 GEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA 1211
Query: 335 INRLMRQSQQERRIAVQL-----------MHVRHEKEVLWQNRIFREKQHEERRLKDFQD 383
+ L Q +Q +R L + E VL Q + +E +H++++L+
Sbjct: 1212 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAK--QEVEHKKKKLEAQVQ 1269
Query: 384 ALDREAALAKQAKIDFEEQFLKEKRFHDQIAVERAQARYEKHYSVCAEILDQIVDLSTKV 443
L + + ++A+ + L +K Q VE + ++ + LS+++
Sbjct: 1270 ELQSKCSDGERARAE-----LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQL 1324
Query: 444 ADYRMLTNNLIPYKL 458
D + L KL
Sbjct: 1325 QDTQELLQEETRQKL 1339
Score = 30.0 bits (66), Expect = 5.3
Identities = 34/166 (20%), Positives = 71/166 (42%), Gaps = 8/166 (4%)
Query: 179 ERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMMKKK 238
ER K E +E+Q R + + +++ A+ K T+ ALEA+ ++
Sbjct: 1783 ERSTAQKNESARQQLERQNKELRSK---LHEMEGAV----KSKFKSTIAALEAKIAQLEE 1835
Query: 239 KEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQKRLE 298
+ ++ ++ ++L +KD + KE + D + +K+++++LE
Sbjct: 1836 QVEQEAREKQAATKSLKQKDKKLKEILLQVE-DERKMAEQYKEQAEKGNARVKQLKRQLE 1894
Query: 299 EDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQ 344
E ++ RRKL + A E+ E RE + +R+ +
Sbjct: 1895 EAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNE 1940
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 50.8 bits (120), Expect = 3e-06
Identities = 48/220 (21%), Positives = 100/220 (45%), Gaps = 19/220 (8%)
Query: 291 KKIQKRLEEDAFAREQREKR---RRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERR 347
K+ Q++ E + EQ+ + + LL +QL +A+ E Y E + + + +QE
Sbjct: 872 KERQQKAENELKELEQKHSQLTEEKNLLQEQL---QAETELYAEAEEMRVRLAAKKQELE 928
Query: 348 IAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKEK 407
+ M R E+E ++ E++ +++ D ++ L+ E A ++ +++ K K
Sbjct: 929 EILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIK 988
Query: 408 RFHDQIAV-ERAQARYEKHYSVCAEILDQIVDLSTKVADYRMLTNNLIPYKLMHDWKELF 466
+ D+I V + + K + E +I DL+T +A+ NL K H+
Sbjct: 989 KLEDEILVMDDQNNKLSKERKLLEE---RISDLTTNLAEEEEKAKNLTKLKNKHE----- 1040
Query: 467 FNAKPIYEQASVKTLPANPSREQLTELEKRDLLDTNDYEE 506
+ + V+ SR++L +L+++ D +D+ E
Sbjct: 1041 ----SMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE 1076
Score = 50.4 bits (119), Expect = 4e-06
Identities = 64/291 (21%), Positives = 138/291 (47%), Gaps = 24/291 (8%)
Query: 153 MRITYRFQEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQA 212
+R+ + QE + + E A L E+ +R Q+L+ E++ + L + + E A+ +
Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEE-DRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK- 975
Query: 213 AIIQIPKPASNRTLKALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDT 272
+Q+ K + +K LE + ++ +D +++ K L+++ + + + + +
Sbjct: 976 --LQLEKVTAEAKIKKLEDEILVM-----DDQNNKLSKERKLLEERI-SDLTTNLAEEEE 1027
Query: 273 AGQTTTDLLNTYSDDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREE 332
+ T L N + + I +++ RL+++ +R++ EK +RKL D HE + A +
Sbjct: 1028 KAKNLTKLKNKH--ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE--QIADLQA 1083
Query: 333 QLINRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAAL- 391
Q+ M+ +++E + L R + E+ +N ++ + E + D Q+ LD E A
Sbjct: 1084 QIAELKMQLAKKEEELQAAL--ARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAAR 1141
Query: 392 --AKQAKIDFEEQF--LK---EKRFHDQIAVERAQARYEKHYSVCAEILDQ 435
A++ K D E+ LK E + +A+ E+ +V + LD+
Sbjct: 1142 NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1192
Score = 43.1 bits (100), Expect = 6e-04
Identities = 73/346 (21%), Positives = 151/346 (43%), Gaps = 39/346 (11%)
Query: 116 EMQTMQRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLHF 175
E++ +R +++ MK+ E L + D L R+ Q + DL
Sbjct: 1536 ELEKSKRALETQMEEMKTQL--EELEDELQATEDAKL-RLEVNMQALKGQFERDLQARDE 1592
Query: 176 EKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMA----KIQAAIIQIPKPASNRTLKALEA 231
+ E+ ++L+ + ++ E + + R+Q + A K++ + + A + EA
Sbjct: 1593 QNEEKRRQLQRQLHEYETELE--DERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEA 1650
Query: 232 QKMMKK-KKEAEDVADEIKKFEALIKKD---LQAKESASKTSLDTAGQTTTDLLNTYSDD 287
K ++K + + +D E++ +A +D AKE+ K A DL+ D
Sbjct: 1651 IKQLRKLQAQMKDFQRELE--DARASRDEIFATAKENEKK-----AKSLEADLMQLQEDL 1703
Query: 288 EYIKKIQKR--LEEDAFARE-----------QREKRRRKLLMDQLIAHEAQEEAYREEQL 334
++ +K+ LE++ A E Q EKRR + + QL E +EE E +
Sbjct: 1704 AAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQL-EEELEEEQGNMEAM 1762
Query: 335 INRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERR--LKDFQDALD---REA 389
+R+ + +QQ +++ +L R + R E+Q++E R L + + A+ +
Sbjct: 1763 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST 1822
Query: 390 ALAKQAKIDFEEQFLKEKRFHDQIAVERAQARYEKHYSVCAEILDQ 435
A +AKI E+ ++++ Q A + + + +K + ++ D+
Sbjct: 1823 IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDE 1868
Score = 40.4 bits (93), Expect = 0.004
Identities = 56/276 (20%), Positives = 120/276 (43%), Gaps = 24/276 (8%)
Query: 176 EKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMM 235
+K +F +L E++ +I +Y + R + E A+ + A L+A E +
Sbjct: 1455 KKQRKFDQLLAEEK--NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERT 1512
Query: 236 KK--KKEAEDVA---DEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEY- 289
K K E ED+ D++ K ++K +A E+ + + T + D L D +
Sbjct: 1513 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME-EMKTQLEELEDELQATEDAKLR 1571
Query: 290 ----IKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQE 345
++ ++ + E D AR+++ + +R+ L QL +E + E R+++ L ++++
Sbjct: 1572 LEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQR---ALAAAAKKK 1628
Query: 346 RRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLK 405
++ + ++ + + + ++ + + ++KDFQ L+ A + +E K
Sbjct: 1629 LEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKK 1688
Query: 406 EKRF--------HDQIAVERAQARYEKHYSVCAEIL 433
K D A ERA+ + + AE L
Sbjct: 1689 AKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL 1724
Score = 40.0 bits (92), Expect = 0.005
Identities = 75/375 (20%), Positives = 153/375 (40%), Gaps = 53/375 (14%)
Query: 126 LRLQNMKSDTFQERLRHMIPRQTDFN--LMRITYRFQEKYKHVKEDLAHLHFEKLERFQK 183
L+L+ + ++ ++L I D N L + +E+ + +LA EK + K
Sbjct: 976 LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE-EKAKNLTK 1034
Query: 184 LKEEQRCF------DIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMMKK 237
LK + ++K+ +R+ ++ K++ + ++ + E + + K
Sbjct: 1035 LKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK 1094
Query: 238 KKEAEDVA-----DEIKKFEALIKK---------DLQAKESASKTSLDTAGQTTTDLLNT 283
K+E A DEI + +KK DLQ + + + + A + DL
Sbjct: 1095 KEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDL--- 1151
Query: 284 YSDDEYIK-KIQKRLEEDAFAREQREKRR------RKLLMDQLIAHEAQEEAYREE--QL 334
+ E +K +++ L+ A +E R KR +K L ++ +HEAQ + R++ Q
Sbjct: 1152 GEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA 1211
Query: 335 INRLMRQSQQERRIAVQL-----------MHVRHEKEVLWQNRIFREKQHEERRLKDFQD 383
+ L Q +Q +R L + E VL Q + +E +H++++L+
Sbjct: 1212 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAK--QEVEHKKKKLEAQVQ 1269
Query: 384 ALDREAALAKQAKIDFEEQFLKEKRFHDQIAVERAQARYEKHYSVCAEILDQIVDLSTKV 443
L + + ++A+ + L +K Q VE + ++ + LS+++
Sbjct: 1270 ELQSKCSDGERARAE-----LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQL 1324
Query: 444 ADYRMLTNNLIPYKL 458
D + L KL
Sbjct: 1325 QDTQELLQEETRQKL 1339
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 50.8 bits (120), Expect = 3e-06
Identities = 48/220 (21%), Positives = 100/220 (45%), Gaps = 19/220 (8%)
Query: 291 KKIQKRLEEDAFAREQREKR---RRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERR 347
K+ Q++ E + EQ+ + + LL +QL +A+ E Y E + + + +QE
Sbjct: 865 KERQQKAENELKELEQKHSQLTEEKNLLQEQL---QAETELYAEAEEMRVRLAAKKQELE 921
Query: 348 IAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKEK 407
+ M R E+E ++ E++ +++ D ++ L+ E A ++ +++ K K
Sbjct: 922 EILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIK 981
Query: 408 RFHDQIAV-ERAQARYEKHYSVCAEILDQIVDLSTKVADYRMLTNNLIPYKLMHDWKELF 466
+ D+I V + + K + E +I DL+T +A+ NL K H+
Sbjct: 982 KLEDEILVMDDQNNKLSKERKLLEE---RISDLTTNLAEEEEKAKNLTKLKNKHE----- 1033
Query: 467 FNAKPIYEQASVKTLPANPSREQLTELEKRDLLDTNDYEE 506
+ + V+ SR++L +L+++ D +D+ E
Sbjct: 1034 ----SMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE 1069
Score = 50.4 bits (119), Expect = 4e-06
Identities = 64/291 (21%), Positives = 138/291 (47%), Gaps = 24/291 (8%)
Query: 153 MRITYRFQEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQA 212
+R+ + QE + + E A L E+ +R Q+L+ E++ + L + + E A+ +
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEE-DRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK- 968
Query: 213 AIIQIPKPASNRTLKALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDT 272
+Q+ K + +K LE + ++ +D +++ K L+++ + + + + +
Sbjct: 969 --LQLEKVTAEAKIKKLEDEILVM-----DDQNNKLSKERKLLEERI-SDLTTNLAEEEE 1020
Query: 273 AGQTTTDLLNTYSDDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREE 332
+ T L N + + I +++ RL+++ +R++ EK +RKL D HE + A +
Sbjct: 1021 KAKNLTKLKNKH--ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE--QIADLQA 1076
Query: 333 QLINRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAAL- 391
Q+ M+ +++E + L R + E+ +N ++ + E + D Q+ LD E A
Sbjct: 1077 QIAELKMQLAKKEEELQAAL--ARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAAR 1134
Query: 392 --AKQAKIDFEEQF--LK---EKRFHDQIAVERAQARYEKHYSVCAEILDQ 435
A++ K D E+ LK E + +A+ E+ +V + LD+
Sbjct: 1135 NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1185
Score = 43.1 bits (100), Expect = 6e-04
Identities = 73/346 (21%), Positives = 151/346 (43%), Gaps = 39/346 (11%)
Query: 116 EMQTMQRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLHF 175
E++ +R +++ MK+ E L + D L R+ Q + DL
Sbjct: 1529 ELEKSKRALETQMEEMKTQL--EELEDELQATEDAKL-RLEVNMQALKGQFERDLQARDE 1585
Query: 176 EKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMA----KIQAAIIQIPKPASNRTLKALEA 231
+ E+ ++L+ + ++ E + + R+Q + A K++ + + A + EA
Sbjct: 1586 QNEEKRRQLQRQLHEYETELE--DERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEA 1643
Query: 232 QKMMKK-KKEAEDVADEIKKFEALIKKD---LQAKESASKTSLDTAGQTTTDLLNTYSDD 287
K ++K + + +D E++ +A +D AKE+ K A DL+ D
Sbjct: 1644 IKQLRKLQAQMKDFQRELE--DARASRDEIFATAKENEKK-----AKSLEADLMQLQEDL 1696
Query: 288 EYIKKIQKR--LEEDAFARE-----------QREKRRRKLLMDQLIAHEAQEEAYREEQL 334
++ +K+ LE++ A E Q EKRR + + QL E +EE E +
Sbjct: 1697 AAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQL-EEELEEEQGNMEAM 1755
Query: 335 INRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERR--LKDFQDALD---REA 389
+R+ + +QQ +++ +L R + R E+Q++E R L + + A+ +
Sbjct: 1756 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST 1815
Query: 390 ALAKQAKIDFEEQFLKEKRFHDQIAVERAQARYEKHYSVCAEILDQ 435
A +AKI E+ ++++ Q A + + + +K + ++ D+
Sbjct: 1816 IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDE 1861
Score = 40.4 bits (93), Expect = 0.004
Identities = 56/276 (20%), Positives = 120/276 (43%), Gaps = 24/276 (8%)
Query: 176 EKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMM 235
+K +F +L E++ +I +Y + R + E A+ + A L+A E +
Sbjct: 1448 KKQRKFDQLLAEEK--NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERT 1505
Query: 236 KK--KKEAEDVA---DEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEY- 289
K K E ED+ D++ K ++K +A E+ + + T + D L D +
Sbjct: 1506 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME-EMKTQLEELEDELQATEDAKLR 1564
Query: 290 ----IKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQE 345
++ ++ + E D AR+++ + +R+ L QL +E + E R+++ L ++++
Sbjct: 1565 LEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQR---ALAAAAKKK 1621
Query: 346 RRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLK 405
++ + ++ + + + ++ + + ++KDFQ L+ A + +E K
Sbjct: 1622 LEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKK 1681
Query: 406 EKRF--------HDQIAVERAQARYEKHYSVCAEIL 433
K D A ERA+ + + AE L
Sbjct: 1682 AKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL 1717
Score = 40.0 bits (92), Expect = 0.005
Identities = 75/375 (20%), Positives = 153/375 (40%), Gaps = 53/375 (14%)
Query: 126 LRLQNMKSDTFQERLRHMIPRQTDFN--LMRITYRFQEKYKHVKEDLAHLHFEKLERFQK 183
L+L+ + ++ ++L I D N L + +E+ + +LA EK + K
Sbjct: 969 LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE-EKAKNLTK 1027
Query: 184 LKEEQRCF------DIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMMKK 237
LK + ++K+ +R+ ++ K++ + ++ + E + + K
Sbjct: 1028 LKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK 1087
Query: 238 KKEAEDVA-----DEIKKFEALIKK---------DLQAKESASKTSLDTAGQTTTDLLNT 283
K+E A DEI + +KK DLQ + + + + A + DL
Sbjct: 1088 KEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDL--- 1144
Query: 284 YSDDEYIK-KIQKRLEEDAFAREQREKRR------RKLLMDQLIAHEAQEEAYREE--QL 334
+ E +K +++ L+ A +E R KR +K L ++ +HEAQ + R++ Q
Sbjct: 1145 GEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA 1204
Query: 335 INRLMRQSQQERRIAVQL-----------MHVRHEKEVLWQNRIFREKQHEERRLKDFQD 383
+ L Q +Q +R L + E VL Q + +E +H++++L+
Sbjct: 1205 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAK--QEVEHKKKKLEAQVQ 1262
Query: 384 ALDREAALAKQAKIDFEEQFLKEKRFHDQIAVERAQARYEKHYSVCAEILDQIVDLSTKV 443
L + + ++A+ + L +K Q VE + ++ + LS+++
Sbjct: 1263 ELQSKCSDGERARAE-----LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQL 1317
Query: 444 ADYRMLTNNLIPYKL 458
D + L KL
Sbjct: 1318 QDTQELLQEETRQKL 1332
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 49.7 bits (117), Expect = 6e-06
Identities = 62/278 (22%), Positives = 119/278 (42%), Gaps = 40/278 (14%)
Query: 160 QEKYKHVKEDLAHLHFEKLERFQKLKE-----EQRCFDIEKQYLNRRRQNEIMAKIQAAI 214
+E ++ DL + EK E +KL E E +E+ + +RQ E++A+
Sbjct: 672 EEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQE- 730
Query: 215 IQIPKPASNRTLKALEAQKMMKKKKEAEDVADEIKKFEA---LIKKDLQAKESASKTSLD 271
K A R ALE ++ +++ +D+A++++ + L++ L + +
Sbjct: 731 ----KEALVREKAALEV-RLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEV 785
Query: 272 TAGQTTTDLLNTYSDDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYRE 331
T GQ + E I Q E R KL +D + +A +E
Sbjct: 786 TKGQLEVQIQTVTQAKEVI---------------QGEVRCLKLELDT-----ERSQAEQE 825
Query: 332 EQLINRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAAL 391
R + Q++QE + A++ HEKEV N++ REK +ER Q L +
Sbjct: 826 RDAAARQLAQAEQEGKTALEQQKAAHEKEV---NQL-REKWEKERSW--HQQELAKALES 879
Query: 392 AKQAKIDFEEQFLKEKRFHDQIAVERAQARYEKHYSVC 429
++ K++ E + +++ + I +R + R + ++C
Sbjct: 880 LEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALC 917
Score = 36.2 bits (82), Expect = 0.073
Identities = 65/321 (20%), Positives = 140/321 (43%), Gaps = 48/321 (14%)
Query: 152 LMRITYRFQEKYKHVKEDLAHLHF----------EKLERFQKLKEEQRCFDI---EKQYL 198
L +T +E+ + ++ + +H E ER Q++K ++ + +K++L
Sbjct: 1590 LTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHL 1649
Query: 199 NR---RRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMMKKKKEAEDVADEIKKFEALI 255
+ RR E+M +Q IQ+ + R K LE + + + K + E+ L+
Sbjct: 1650 TQDLERRDQELM--LQKERIQVLEDQRTRQTKILE-EDLEQIKLSLRERGRELTTQRQLM 1706
Query: 256 KKDLQAKESASKTSLDTAGQTTTDLLNTYSD----DEYIKKIQK---RLEEDAFAREQR- 307
++ + + SK + L + + E+I ++Q+ +LE+ ++
Sbjct: 1707 QERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKV 1766
Query: 308 -------EKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQLMHVRHEKE 360
+R +++++ Q EA+E+ +EQ + + ++Q+ L E E
Sbjct: 1767 GETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRA------LAQRDQELE 1820
Query: 361 VLWQNRIFREKQHEERRLKD----FQDALDREAALAKQAKIDFEEQFLKEKRFHDQIAVE 416
L Q + ++ Q +E R+K+ Q AL++ K+ + ++ + +R +++AVE
Sbjct: 1821 ALQQEQ--QQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVE 1878
Query: 417 --RAQARYEKHYSVCAEILDQ 435
R QA E + AE +Q
Sbjct: 1879 GRRVQALEEVLGDLRAESREQ 1899
Score = 36.2 bits (82), Expect = 0.073
Identities = 70/345 (20%), Positives = 138/345 (40%), Gaps = 56/345 (16%)
Query: 87 TEKPGVATKLLYQLYIALQKKKKSGLTGVEMQTMQRLTNLRLQNMKSDTFQER--LRHM- 143
T + + + L Q+ ++L+++ G E+ T ++L R + K + +R L HM
Sbjct: 1675 TRQTKILEEDLEQIKLSLRER------GRELTTQRQLMQERAEEGKGPSKAQRGSLEHMK 1728
Query: 144 -IPRQTDFNL---MRITYRFQEKYKHVKEDLAHLHFEKLERFQKLKE-EQRCFDIEKQYL 198
I R + + + QE +++ L LH + E L + EQ +++Q
Sbjct: 1729 LILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQ 1788
Query: 199 NRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMMKKKKEAEDVADEIKKFEALIKKD 258
R Q E+ K Q+ Q+ + + E + + +++++A+ + +K+
Sbjct: 1789 EAREQGEL--KEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKE-------- 1838
Query: 259 LQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQKRLEEDAFAR-------------- 304
K A + +L+ A T + D K+ +RLEE+
Sbjct: 1839 ---KADALQGALEQAHMTLKERHGELQDH---KEQARRLEEELAVEGRRVQALEEVLGDL 1892
Query: 305 --EQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQLMHVRHEKEVL 362
E RE+ + L + Q A +AQE L Q+ + Q + ++E+
Sbjct: 1893 RAESREQEKALLALQQQCAEQAQEHEVETRAL---------QDSWLQAQAVLKERDQELE 1943
Query: 363 WQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKEK 407
+ +H+E + +AL +EA A + +EQ L E+
Sbjct: 1944 ALRAESQSSRHQEEAARARAEAL-QEALGKAHAALQGKEQHLLEQ 1987
Score = 35.4 bits (80), Expect = 0.13
Identities = 58/304 (19%), Positives = 121/304 (39%), Gaps = 27/304 (8%)
Query: 65 RLEPTLNLLGVQFDQNVAHGIITEKPGVATKLLYQLYIALQKKKKSGLTGVEMQTMQRLT 124
++E + L Q + E+ A L Q+ + +K++ S L + +QT + L
Sbjct: 884 KMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETL-LQTQKELA 942
Query: 125 NL--RLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLHFEKLERFQ 182
+ +L+ ++ D ++L+ Q +++ + QE + +KE A H + L Q
Sbjct: 943 DASQQLERLRQDMKVQKLKE----QETTGILQT--QLQEAQRELKE-AARQHRDDLAALQ 995
Query: 183 KLKEE--QRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMMKKKKE 240
+ Q D++KQ + + Q Q + Q E Q+ +++ +E
Sbjct: 996 EESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQ-------------EVQEKLRETQE 1042
Query: 241 AEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQKRL--E 298
+ E+++ +A + L KE + +L D + + QK L +
Sbjct: 1043 YNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQ 1102
Query: 299 EDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQLMHVRHE 358
+ +E +EK L + + E + E+QL L Q + ++ ++L +
Sbjct: 1103 MELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQ 1162
Query: 359 KEVL 362
E L
Sbjct: 1163 LEAL 1166
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 48.9 bits (115), Expect = 1e-05
Identities = 78/363 (21%), Positives = 150/363 (41%), Gaps = 60/363 (16%)
Query: 116 EMQTMQRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLHF 175
++ RLT + + ++S E+L+ Q + L + + K++L +
Sbjct: 861 QLAAENRLTEM--ETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICH 918
Query: 176 EKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMM 235
+ R ++ EE+RC ++ + + ++ IQ Q+ + S R QK+
Sbjct: 919 DLEARVEE--EEERCQHLQAE------KKKMQQNIQELEEQLEEEESAR-------QKLQ 963
Query: 236 KKKKEAEDVADEIKKFEALIKKDLQAKESASKTSL-DTAGQTTTDLLNTYSDDEYIKK-- 292
+K E ++++ E +I +D K + K L D + TT+L + + K
Sbjct: 964 LEKVTTEAKLKKLEE-EQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLK 1022
Query: 293 ---------IQKRLEEDAFAREQREKRRRKL------LMDQLIAHEAQ------EEAYRE 331
+++RL + R++ EK RRKL L DQ+ +AQ + A +E
Sbjct: 1023 NKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKE 1082
Query: 332 EQLINRLMRQSQQERRIAVQLMHVR-------HEKEVLWQNRIFREKQHEERR------- 377
E+L L R ++ + + L +R +E L R R K +++R
Sbjct: 1083 EELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELE 1142
Query: 378 -LK-DFQDALDREAALAKQAKIDFEEQFLKEKRFHDQIAVERAQAR--YEKHYSVCAEIL 433
LK + +D LD AA + +E + +K ++ AQ + +KH E+
Sbjct: 1143 ALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELA 1202
Query: 434 DQI 436
+Q+
Sbjct: 1203 EQL 1205
Score = 35.4 bits (80), Expect = 0.13
Identities = 92/420 (21%), Positives = 169/420 (40%), Gaps = 41/420 (9%)
Query: 104 LQKKKKSGLTGVEMQTMQRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKY 163
+ K G + E++ +R +++ MK+ E L + D L R+ Q
Sbjct: 1510 MSSKDDVGKSVHELEKSKRALEQQVEEMKTQL--EELEDELQATEDAKL-RLEVNLQAMK 1566
Query: 164 KHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMA--KIQAAIIQIPKPA 221
+ DL + E+ ++L + R + E + ++R + A K++ + +
Sbjct: 1567 AQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHI 1626
Query: 222 SNRTLKALEAQKMMKK-KKEAEDVADEIKKFEALIKKDL-QAKESASKTSLDTAGQTTTD 279
+ EA K ++K + + +D E+ A ++ L QAKE+ K L +
Sbjct: 1627 DSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKK--LKSMEAEMIQ 1684
Query: 280 LLNTYSDDEYIKKIQKRLEEDAFARE-----------QREKRRRKLLMDQLIAHEAQEEA 328
L + E K+ Q + E D A E EKRR + + QL E +EE
Sbjct: 1685 LQEELAAAERAKR-QAQQERDELADEIANSSGKGALALEEKRRLEARIAQL-EEELEEEQ 1742
Query: 329 YREEQLINRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLK--DFQDALD 386
E + +RL + + Q +I L R + R E+Q++E ++K + + +
Sbjct: 1743 GNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVK 1802
Query: 387 ---REAALAKQAKIDFEEQFLKEKRFHDQIAVERAQARYEKHYSVCAEILDQIVDLSTKV 443
+ + A +AKI E+ L + Q A ++ + +K ++L Q+ D
Sbjct: 1803 SKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKK----LKDVLLQVDDERRNA 1858
Query: 444 ADYRMLTNNLIPYKLMHDWKELFFNAKPIYEQASVKTLPANPSREQLTELEKRDLLDTND 503
Y+ + K K+L K E+A + AN SR +L + E D +T D
Sbjct: 1859 EQYKDQAD-----KASTRLKQL----KRQLEEAEEEAQRANASRRKL-QRELEDATETAD 1908
Score = 33.5 bits (75), Expect = 0.48
Identities = 60/302 (19%), Positives = 133/302 (44%), Gaps = 36/302 (11%)
Query: 165 HVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKI-QAAIIQIPKPASN 223
H ++ +L +K ++F +L E++ I +Y R + E A+ + + + +
Sbjct: 1431 HQRQSACNLE-KKQKKFDQLLAEEKT--ISAKYAEERDRAEAEAREKETKALSLARALEE 1487
Query: 224 RTLKALEAQKMMKK-KKEAEDVA---DEIKKFEALIKKDLQAKESASKTSLDTAGQTTTD 279
+ E +++ K+ + E ED+ D++ K ++K +A E + + T + D
Sbjct: 1488 AMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVE-EMKTQLEELED 1546
Query: 280 LLNTYSDDEY-----IKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQL 334
L D + ++ ++ + E D R+++ + ++K L+ Q+ EA+ E R+++
Sbjct: 1547 ELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRS 1606
Query: 335 INRLMRQSQQERRIAVQLMHVRHEKEVLWQNR--IFREKQHEERRLKDFQDALDREAALA 392
+ R +++ + L + + +NR ++ + + ++KD LD A
Sbjct: 1607 MAVAAR-----KKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASR 1661
Query: 393 KQAKIDFEEQFLKEKRFHDQI--------AVERA--QARYEKHYSVCAEILDQIVDLSTK 442
++ +E K K ++ A ERA QA+ E+ E+ D+I + S K
Sbjct: 1662 EEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERD-----ELADEIANSSGK 1716
Query: 443 VA 444
A
Sbjct: 1717 GA 1718
Score = 32.7 bits (73), Expect = 0.81
Identities = 33/180 (18%), Positives = 81/180 (45%), Gaps = 8/180 (4%)
Query: 286 DDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHE---AQEEAYREEQLINRLMRQS 342
++E +K +K+L + E E + +L+ ++L E A+ E E + + +
Sbjct: 851 EEELVKVREKQLAAENRLTEM-ETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAK 909
Query: 343 QQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQ 402
+QE + R E+E + EK+ ++ +++ ++ L+ E + ++ +++
Sbjct: 910 KQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTT 969
Query: 403 FLKEKRF-HDQIAVERAQARYEKHYSVCAEILDQIVDLSTKVADYRMLTNNLIPYKLMHD 461
K K+ +QI +E + K + + D+I + +T + + + +L K H+
Sbjct: 970 EAKLKKLEEEQIILEDQNCKLAKEKKL---LEDRIAEFTTNLTEEEEKSKSLAKLKNKHE 1026
Score = 30.8 bits (68), Expect = 3.1
Identities = 66/309 (21%), Positives = 122/309 (39%), Gaps = 57/309 (18%)
Query: 99 QLYIALQKKKK---SGLTGVEMQTMQRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRI 155
+L + L KK++ + L VE + Q+ NM +E + Q D R
Sbjct: 1073 ELKMQLAKKEEELQAALARVEEEAAQK-------NMALKKIRELESQISELQEDLESERA 1125
Query: 156 TYRFQEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAII 215
+ EK K DL E+LE + E+ +Q L +R+ E+
Sbjct: 1126 SRNKAEKQKR---DLG----EELEALKTELEDTLDSTAAQQELRSKREQEV--------- 1169
Query: 216 QIPKPASNRTLKALEAQ--KMMKKKKEA-EDVADEIKKFEALIKKDLQAKESASKTSLDT 272
I K K EAQ +M +K +A E++A+++++ + + +AK++ +
Sbjct: 1170 NILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGEL 1229
Query: 273 AGQTTTDLLNTYSDDEYIKKIQKRLEEDAFAREQREKRRRKLL---------MDQLIAHE 323
A + L + KK++ +L+E + E+ R +L +D +
Sbjct: 1230 ANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLL 1289
Query: 324 AQEEAYR----------EEQLINR---LMRQSQQERRIAVQLMHVRHEKEVLWQNRIFRE 370
+Q ++ E QL + L +++Q+ ++ +L V EK FRE
Sbjct: 1290 SQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEK------NSFRE 1343
Query: 371 KQHEERRLK 379
+ EE K
Sbjct: 1344 QLEEEEEAK 1352
Score = 29.3 bits (64), Expect = 9.0
Identities = 53/249 (21%), Positives = 101/249 (40%), Gaps = 54/249 (21%)
Query: 102 IALQKKKKSGLTGVEMQTMQRLTNLRLQNMKSDTFQERLR----HMIPRQTDFNLMRITY 157
+AL++K++ +E + Q L + ++ +RL+ + TD NL
Sbjct: 1719 LALEEKRR-----LEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNL----- 1768
Query: 158 RFQEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQI 217
E+ K + A E+ + K+K ++ ++ +Y + ++A I Q+
Sbjct: 1769 ---ERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKY------KASITALEAKIAQL 1819
Query: 218 PKPASNRTLKALEAQKMMKK-KKEAEDVA----DEIKKFEALIKKDLQAKESASKTSLDT 272
+ N T + A K +++ +K+ +DV DE + E Q K+ A K S
Sbjct: 1820 EEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAE-------QYKDQADKASTR- 1871
Query: 273 AGQTTTDLLNTYSDDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYRE- 331
+K+++++LEE ++ RRKL + A E + RE
Sbjct: 1872 -----------------LKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREV 1914
Query: 332 EQLINRLMR 340
L N+L R
Sbjct: 1915 SSLKNKLRR 1923
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 48.9 bits (115), Expect = 1e-05
Identities = 72/329 (21%), Positives = 137/329 (41%), Gaps = 40/329 (12%)
Query: 120 MQRLTNLRLQNMKSDTFQERLRHMIPRQT-------DFNLMRITYRFQEKYKHVKEDLAH 172
++ + +LR + ++S+ E LR + R T + T +K DLA
Sbjct: 483 IKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDLAK 542
Query: 173 LHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQ 232
EKL+R +K K++ + ++ ++ E K S R LE +
Sbjct: 543 KDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEE-------------KGVSERENNELEVE 589
Query: 233 KMMK------KKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSD 286
+ + +++E E+ D+I E+ + D ++ E A+ + D A T +
Sbjct: 590 ESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQA-DLANITCEIAIKQKLI 648
Query: 287 DEYIKKIQKRLE------EDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMR 340
DE ++ QKRL+ E+ Q + R +L DQ++ + E+Y EE+ + +R
Sbjct: 649 DE-LENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKA--KKVR 705
Query: 341 QSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLK----DFQDALDREAALAKQAK 396
+++ A+ R + R+ + + E++LK D + + L KQ K
Sbjct: 706 SEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMK 765
Query: 397 IDFEEQFLKEKRFHDQIAVERAQARYEKH 425
+ E+ L E R + +IA + R H
Sbjct: 766 EEQEKARLTESRRNREIAQLKKDQRKRDH 794
Score = 37.4 bits (85), Expect = 0.033
Identities = 49/279 (17%), Positives = 123/279 (44%), Gaps = 26/279 (9%)
Query: 112 LTGVEMQTMQRLTNLRLQ-NMKSDTFQERLRHMIPRQTDF-NLMRITYRFQEKYKHVKED 169
L VE + ++ +R + K + L+ + Q + L++ +++++ K +++D
Sbjct: 690 LGSVESYSEEKAKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQD 749
Query: 170 LAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKAL 229
+ + K+ +++KEEQ EK L R+N +A+++ + + L+ L
Sbjct: 750 VMEMKKTKVRLMKQMKEEQ-----EKARLTESRRNREIAQLKK-----DQRKRDHQLRLL 799
Query: 230 EAQK------MMKKKKEAEDVADEIK----KFEALIKKDLQAKESASKTSLDTAGQTTTD 279
EAQK + +K +E + +++ K + + L + ++ ++ + +A TD
Sbjct: 800 EAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDAPAQDTGSSAAAVETD 859
Query: 280 LLNTYSDDEY---IKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLIN 336
T + + + ++Q L A +++ +R+ L I+ A+ + E+ +
Sbjct: 860 ASRTGAQQKMRIPVARVQ-ALPTPATNGNRKKYQRKGLTGRVFISKTARMKWQLLERRVT 918
Query: 337 RLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEE 375
++ Q + + + ++E L + R K+ E+
Sbjct: 919 DIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREK 957
>gi|225579095 S-phase cyclin A-associated protein in the ER isoform
b [Homo sapiens]
Length = 1154
Score = 48.5 bits (114), Expect = 1e-05
Identities = 65/300 (21%), Positives = 126/300 (42%), Gaps = 33/300 (11%)
Query: 149 DFNLMRITYRFQEKYKH-------VKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRR 201
D+N + Y +E ++ V+E+ A + +KL R I + +++
Sbjct: 243 DWNDVLADYEARESWRQNTSWGDIVEEEPARPPGHGIHMHEKLSSPSRKRTIAE---SKK 299
Query: 202 RQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMMKKKKEAEDVAD------EIKKFEALI 255
+ E K Q ++ + + + K LE +K ++K KE ++ D E K A
Sbjct: 300 KHEEKQMKAQQLREKLREEKTLKLQKLLEREKDVRKWKE--ELLDQRRRMMEEKLLHAEF 357
Query: 256 KKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQKRLEE-DAFAREQREKRRRKL 314
K+++Q + K + A +NT + +L+E + E +E+R+R+
Sbjct: 358 KREVQLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNELQEERQRR- 416
Query: 315 LMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQ--LMHVRHEKEVLWQNRIFREKQ 372
QEE ++ + R + ER+ V+ LM + ++ + Q R +EK
Sbjct: 417 ----------QEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEKA 466
Query: 373 HEERRLKDFQDALDREAALAKQAKIDFEEQFLKEKRFHDQIAVERAQARYEKHYSVCAEI 432
E+ + +D +R AAL + EE K + HD+ ++ R + E+ AE+
Sbjct: 467 REDAARERARDREERLAALTAAQQEAMEELQKKIQLKHDE-SIRRHMEQIEQRKEKAAEL 525
Score = 36.6 bits (83), Expect = 0.056
Identities = 41/187 (21%), Positives = 88/187 (47%), Gaps = 33/187 (17%)
Query: 287 DEYIKKIQKRLEEDAFAREQREK---RRRKLLMDQLIAHEAQEE---------AYREEQL 334
+E K+QK LE + R+ +E+ +RR+++ ++L+ E + E A EE
Sbjct: 317 EEKTLKLQKLLEREKDVRKWKEELLDQRRRMMEEKLLHAEFKREVQLQAIVKKAQEEEAK 376
Query: 335 INRLM----RQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAA 390
+N + ++Q +R L ++ ++ L + + R+++ EE++ +D + +R+ A
Sbjct: 377 VNEIAFINTLEAQNKRHDV--LSKLKEYEQRLNELQEERQRRQEEKQARD-EAVQERKRA 433
Query: 391 LAKQAKIDFEEQFLKEK--------------RFHDQIAVERAQARYEKHYSVCAEILDQI 436
L + + EE +K K + + A ERA+ R E+ ++ A + +
Sbjct: 434 LEAERQARVEELLMKRKEQEARIEQQRQEKEKAREDAARERARDREERLAALTAAQQEAM 493
Query: 437 VDLSTKV 443
+L K+
Sbjct: 494 EELQKKI 500
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.131 0.359
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,075,323
Number of Sequences: 37866
Number of extensions: 732705
Number of successful extensions: 6610
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 95
Number of HSP's successfully gapped in prelim test: 613
Number of HSP's that attempted gapping in prelim test: 3871
Number of HSP's gapped (non-prelim): 1886
length of query: 514
length of database: 18,247,518
effective HSP length: 107
effective length of query: 407
effective length of database: 14,195,856
effective search space: 5777713392
effective search space used: 5777713392
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.