Search of human proteins with 11345454

Search of human proteins with 11345454

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11345454 Fanconi anemia, complementation group E [Homo
sapiens]
         (536 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11345454 Fanconi anemia, complementation group E [Homo sapiens]   1058   0.0  
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]     45   2e-04
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    40   0.005
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    40   0.005
gi|83716024 kinesin family member 21B [Homo sapiens]                   39   0.009
gi|55741655 anoctamin 8 [Homo sapiens]                                 39   0.016
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami...    39   0.016
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam...    39   0.016
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam...    39   0.016
gi|17136078 VGF nerve growth factor inducible precursor [Homo sa...    39   0.016
gi|38176300 nestin [Homo sapiens]                                      38   0.027
gi|13376339 plasticity-related protein 2 [Homo sapiens]                38   0.027
gi|149192871 OTU domain containing 3 [Homo sapiens]                    38   0.027
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]          37   0.035
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     37   0.045
gi|148806928 hypothetical protein LOC57482 [Homo sapiens]              37   0.059
gi|38569484 kinesin family member 21A [Homo sapiens]                   37   0.059
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo...    37   0.059
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo...    37   0.059
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             37   0.059
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            36   0.077
gi|33695153 guanine nucleotide binding protein (G protein), alph...    36   0.077
gi|157042792 coiled-coil domain containing 64B [Homo sapiens]          36   0.077
gi|71274144 AT hook, DNA binding motif, containing 1 [Homo sapiens]    36   0.077
gi|116256350 tuberous sclerosis 2 isoform 4 [Homo sapiens]             36   0.10 
gi|116256352 tuberous sclerosis 2 isoform 1 [Homo sapiens]             36   0.10 
gi|167412124 tuberous sclerosis 2 isoform 5 [Homo sapiens]             36   0.10 
gi|67188445 CTD (carboxy-terminal domain, RNA polymerase II, pol...    36   0.10 
gi|239749365 PREDICTED: hypothetical protein XP_002347014 [Homo ...    36   0.10 
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    36   0.10 

>gi|11345454 Fanconi anemia, complementation group E [Homo sapiens]
          Length = 536

 Score = 1058 bits (2735), Expect = 0.0
 Identities = 536/536 (100%), Positives = 536/536 (100%)

Query: 1   MATPDAGLPGAEGVEPAPWAQLEAPARLLLQALQAGPEGARRGLGVLRALGSRGWEPFDW 60
           MATPDAGLPGAEGVEPAPWAQLEAPARLLLQALQAGPEGARRGLGVLRALGSRGWEPFDW
Sbjct: 1   MATPDAGLPGAEGVEPAPWAQLEAPARLLLQALQAGPEGARRGLGVLRALGSRGWEPFDW 60

Query: 61  GRLLEALCREEPVVQGPDGRLELKPLLLRLPRICQRNLMSLLMAVRPSLPESGLLSVLQI 120
           GRLLEALCREEPVVQGPDGRLELKPLLLRLPRICQRNLMSLLMAVRPSLPESGLLSVLQI
Sbjct: 61  GRLLEALCREEPVVQGPDGRLELKPLLLRLPRICQRNLMSLLMAVRPSLPESGLLSVLQI 120

Query: 121 AQQDLAPDPDAWLRALGELLRRDLGVGTSMEGASPLSERCQRQLQSLCRGLGLGGRRLKS 180
           AQQDLAPDPDAWLRALGELLRRDLGVGTSMEGASPLSERCQRQLQSLCRGLGLGGRRLKS
Sbjct: 121 AQQDLAPDPDAWLRALGELLRRDLGVGTSMEGASPLSERCQRQLQSLCRGLGLGGRRLKS 180

Query: 181 PQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERPEHKSLE 240
           PQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERPEHKSLE
Sbjct: 181 PQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERPEHKSLE 240

Query: 241 SLADGGSASPIKDQPVMAVKTGEDGSNLDDAKGLAESLELPKAIQDQLPRLQQLLKTLEE 300
           SLADGGSASPIKDQPVMAVKTGEDGSNLDDAKGLAESLELPKAIQDQLPRLQQLLKTLEE
Sbjct: 241 SLADGGSASPIKDQPVMAVKTGEDGSNLDDAKGLAESLELPKAIQDQLPRLQQLLKTLEE 300

Query: 301 GLEGLEDAPPVELQLLHECSPSQMDLLCAQLQLPQLSDLGLLRLCTWLLALSPDLSLSNA 360
           GLEGLEDAPPVELQLLHECSPSQMDLLCAQLQLPQLSDLGLLRLCTWLLALSPDLSLSNA
Sbjct: 301 GLEGLEDAPPVELQLLHECSPSQMDLLCAQLQLPQLSDLGLLRLCTWLLALSPDLSLSNA 360

Query: 361 TVLTRSLFLGRILSLTSSASRLLTTALTSFCAKYTYPVCSALLDPVLQAPGTGPAQTELL 420
           TVLTRSLFLGRILSLTSSASRLLTTALTSFCAKYTYPVCSALLDPVLQAPGTGPAQTELL
Sbjct: 361 TVLTRSLFLGRILSLTSSASRLLTTALTSFCAKYTYPVCSALLDPVLQAPGTGPAQTELL 420

Query: 421 CCLVKMESLEPDAQVLMLGQILELPWKEETFLVLQSLLERQVEMTPEKFSVLMEKLCKKG 480
           CCLVKMESLEPDAQVLMLGQILELPWKEETFLVLQSLLERQVEMTPEKFSVLMEKLCKKG
Sbjct: 421 CCLVKMESLEPDAQVLMLGQILELPWKEETFLVLQSLLERQVEMTPEKFSVLMEKLCKKG 480

Query: 481 LAATTSMAYAKLMLTVMTKYQANITETQRLGLAMALEPNTTFLRKSLKAALKHLGP 536
           LAATTSMAYAKLMLTVMTKYQANITETQRLGLAMALEPNTTFLRKSLKAALKHLGP
Sbjct: 481 LAATTSMAYAKLMLTVMTKYQANITETQRLGLAMALEPNTTFLRKSLKAALKHLGP 536


>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
          Length = 569

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 49/202 (24%), Positives = 89/202 (44%), Gaps = 15/202 (7%)

Query: 132 WLRALGELLRRDLGVGTSMEGASPLSERC---QRQLQSLCRGLGLGG-RRLKSPQAPDPE 187
           +L+ L E  R++L   T M     L   C   +R+++ + + + L G R +  P AP P 
Sbjct: 276 FLKGLSEFFRKELLWSTEMADLDELILECVEIERKVR-VPKPIPLPGVRNIIFPFAPSPN 334

Query: 188 EEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCW-------EEEEDHEKERPEHKSLE 240
           EEE+ D +   +  +D E        K   KR+R +       EEEE  ++E  + K  +
Sbjct: 335 EEESEDEEYYSE-DEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEK 393

Query: 241 SLADGGSASPIKDQPVMAVKTGEDGSNLDDAKGLAESLELPKAIQDQLPRLQQLLKTLEE 300
              +       +++  +  K  E+G + D+     +  + P+    Q P  ++    +EE
Sbjct: 394 EEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEE 453

Query: 301 GLEGLEDAPPVELQLLHECSPS 322
             E L++A   +L  L E  P+
Sbjct: 454 --EPLDEAQDDDLDELMEMEPT 473


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 38/138 (27%), Positives = 64/138 (46%), Gaps = 8/138 (5%)

Query: 176  RRLKSPQAPDPEEEENRDS-QQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERP 234
            +R ++  A   E EEN+ S +Q  KRR+   +E +S E K   +     +EEE+ E+E  
Sbjct: 1362 QRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEE 1421

Query: 235  EHKSLESLADGGSASPIKDQPVMAVKTGEDGSNLDDAKGLAESLELPKAIQDQLPRLQQL 294
            E +  +   D  S SP K +  +     +D    +    L E  E  K I ++    ++L
Sbjct: 1422 EEEEEDENDD--SKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKL 1479

Query: 295  LKTLEEGLEGLEDAPPVE 312
             + +E     +EDA P +
Sbjct: 1480 REVIE-----IEDASPTK 1492


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 38/138 (27%), Positives = 64/138 (46%), Gaps = 8/138 (5%)

Query: 176  RRLKSPQAPDPEEEENRDS-QQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERP 234
            +R ++  A   E EEN+ S +Q  KRR+   +E +S E K   +     +EEE+ E+E  
Sbjct: 1400 QRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEE 1459

Query: 235  EHKSLESLADGGSASPIKDQPVMAVKTGEDGSNLDDAKGLAESLELPKAIQDQLPRLQQL 294
            E +  +   D  S SP K +  +     +D    +    L E  E  K I ++    ++L
Sbjct: 1460 EEEEEDENDD--SKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKL 1517

Query: 295  LKTLEEGLEGLEDAPPVE 312
             + +E     +EDA P +
Sbjct: 1518 REVIE-----IEDASPTK 1530


>gi|83716024 kinesin family member 21B [Homo sapiens]
          Length = 1624

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 43/156 (27%), Positives = 66/156 (42%), Gaps = 19/156 (12%)

Query: 148 TSMEGASPLSERCQRQLQSLCRGLGLGGRRLKSPQAPDPEEEENRDSQQPGKRRKDSEEE 207
           +SME AS +  R ++ L+ L +   +  RR    ++P+ E  + R   Q     +  E E
Sbjct: 532 SSMEDASEVIRRAKQDLERL-KKKEVRQRR----KSPEKEAFKKRAKLQQENSEETDENE 586

Query: 208 AASPEGKRVPKRLRCWEEEEDHEKERPEHKSLESLADGGSASPIKDQPVMAVKTGEDGSN 267
           A   E +R        EEEE  E E  +  S ESL D  S    K+    A         
Sbjct: 587 AEEEEEERDESGC---EEEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQA--------- 634

Query: 268 LDDAKGLAESLELPKAIQDQLPRLQQLLKTLEEGLE 303
             D   L   +E+ + + D+L   Q+ L+TL+   E
Sbjct: 635 --DLADLTCEIEIKQKLIDELENSQRRLQTLKHQYE 668


>gi|55741655 anoctamin 8 [Homo sapiens]
          Length = 1232

 Score = 38.5 bits (88), Expect = 0.016
 Identities = 37/109 (33%), Positives = 48/109 (44%), Gaps = 7/109 (6%)

Query: 133 LRALGELLRRDLGVGTSMEGASPLSERCQRQL-QSLCRGLGLGGRRLKSPQAPDPEEEEN 191
           LRA+ EL R  LG+   +    P   R + Q  +    G G GGRR  S     PEEEE 
Sbjct: 502 LRAVWELARALLGL---LSLRRPAPRRLEPQADEGGGGGSGGGGRRCLSGGCGAPEEEEE 558

Query: 192 RDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERPEHKSLE 240
               +  +  +  EE    P GK   +     EEEED E+E  E +  E
Sbjct: 559 AALVERRRAGEGGEEGDGPPGGKEEDED---DEEEEDEEEEEDEEEGEE 604


>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member E isoform 1 [Homo sapiens]
          Length = 268

 Score = 38.5 bits (88), Expect = 0.016
 Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 5/73 (6%)

Query: 173 LGGRRLKSPQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKE 232
           L G   +  +APD EEE++ D  +  +  ++ E EA  PEG    +     EEEED +++
Sbjct: 145 LDGFDQEDNEAPDSEEEDDEDGDEDDE--EEEENEAGPPEGYEEEEE---EEEEEDEDED 199

Query: 233 RPEHKSLESLADG 245
             E ++   L +G
Sbjct: 200 EDEDEAGSELGEG 212


>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
           family, member E isoform 2 [Homo sapiens]
          Length = 227

 Score = 38.5 bits (88), Expect = 0.016
 Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 5/73 (6%)

Query: 173 LGGRRLKSPQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKE 232
           L G   +  +APD EEE++ D  +  +  ++ E EA  PEG    +     EEEED +++
Sbjct: 104 LDGFDQEDNEAPDSEEEDDEDGDEDDE--EEEENEAGPPEGYEEEEE---EEEEEDEDED 158

Query: 233 RPEHKSLESLADG 245
             E ++   L +G
Sbjct: 159 EDEDEAGSELGEG 171


>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
           family, member E isoform 3 [Homo sapiens]
          Length = 220

 Score = 38.5 bits (88), Expect = 0.016
 Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 5/73 (6%)

Query: 173 LGGRRLKSPQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKE 232
           L G   +  +APD EEE++ D  +  +  ++ E EA  PEG    +     EEEED +++
Sbjct: 97  LDGFDQEDNEAPDSEEEDDEDGDEDDE--EEEENEAGPPEGYEEEEE---EEEEEDEDED 151

Query: 233 RPEHKSLESLADG 245
             E ++   L +G
Sbjct: 152 EDEDEAGSELGEG 164


>gi|17136078 VGF nerve growth factor inducible precursor [Homo
           sapiens]
          Length = 615

 Score = 38.5 bits (88), Expect = 0.016
 Identities = 43/170 (25%), Positives = 68/170 (40%), Gaps = 35/170 (20%)

Query: 161 QRQLQSLCRGLGLGGRRLK--SPQAPDPEEEENRDSQQPGKRRKDSEE-------EAASP 211
           Q  LQ   R  GLGGR L+  + +     EEE  + ++ G   +  EE       EA + 
Sbjct: 334 QYLLQGGARQRGLGGRGLQEAAEERESAREEEEAEQERRGGEERVGEEDEEAAEAEAEAE 393

Query: 212 EGKRVPKRLRCWEEEEDHE---------KERPEH--KSLESLADGGSASPIKDQPVMAVK 260
           E +R  +    + EEED E         +E P H  K  E   +GG     ++       
Sbjct: 394 EAERARQNALLFAEEEDGEAGAEDKRSQEETPGHRRKEAEGTEEGGEEEDDEEM------ 447

Query: 261 TGEDGSNLDDAKGLAESLELPKAIQDQLPRLQQLLKTLEEGLEGLEDAPP 310
              D   +D    L+  L LP         +  +++ +EE  +  ++APP
Sbjct: 448 ---DPQTIDSLIELSTKLHLP------ADDVVSIIEEVEEKRKRKKNAPP 488


>gi|38176300 nestin [Homo sapiens]
          Length = 1621

 Score = 37.7 bits (86), Expect = 0.027
 Identities = 43/164 (26%), Positives = 75/164 (45%), Gaps = 31/164 (18%)

Query: 178 LKSPQAPDPEEEENRDSQQPGKR-----RKDSE-------EEAASPEGKRVPK-RLRCWE 224
           L  P +PD    E +D +  G R     R + E       E+  + EGK V   +   WE
Sbjct: 466 LAPPLSPDHSSLEAKDGESGGSRVFSICRGEGEGQIWGLVEKETAIEGKVVSSLQQEIWE 525

Query: 225 EEEDHEKERP------EHKSLESLADGGSASPIKDQPVMAVKTGEDGSNLDDAKGLAESL 278
           EE+ + KE        E ++L+SL +    S         +KT E+ S+    +   E+ 
Sbjct: 526 EEDLNRKEIQDSQVPLEKETLKSLGEEIQES---------LKTLENQSHETLER---ENQ 573

Query: 279 ELPKAIQDQLPRLQQLLKTLEEGLEGLEDAPPVELQLLHECSPS 322
           E P+++++ L  L+ L K  +E L+ +E   P+E + + +  P+
Sbjct: 574 ECPRSLEEDLETLKSLEKENKELLKDVEVVRPLEKEAVGQLKPT 617



 Score = 33.9 bits (76), Expect = 0.38
 Identities = 50/212 (23%), Positives = 87/212 (41%), Gaps = 29/212 (13%)

Query: 123 QDLAPDPDAWLRALGELLRRDLGVGTSMEGASPLSERCQRQLQSLCRGLGLGGRRLKSPQ 182
           Q L  +    +++L   L   L  GT  +    L    Q  L+SL          L+SP+
Sbjct: 626 QSLQKENQELMKSLEGNLETFLFPGTENQ---ELVSSLQENLESLTALEKENQEPLRSPE 682

Query: 183 APDPEEEE--NRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEED---HEKERPEHK 237
             D E      +++Q+P +  +D  +EA     K   + L+  EEE+       E   HK
Sbjct: 683 VGDEEALRPLTKENQEPLRSLEDENKEAFRSLEKENQEPLKTLEEEDQSIVRPLETENHK 742

Query: 238 SLESLADGGSAS-------------PIKDQPVMAVKTGEDGSNLDDAKGLAESLELPKAI 284
           SL SL +    +              + +Q  M ++  E   +L+  K L + +  P   
Sbjct: 743 SLRSLEEQDQETLRTLEKETQQRRRSLGEQDQMTLRPPEK-VDLEPLKSLDQEIARPLEN 801

Query: 285 QDQLPRLQQLLKTLEEGLEGLEDAPPVELQLL 316
           ++     Q+ LK+L+E  E +E    +E ++L
Sbjct: 802 EN-----QEFLKSLKE--ESVEAVKSLETEIL 826


>gi|13376339 plasticity-related protein 2 [Homo sapiens]
          Length = 746

 Score = 37.7 bits (86), Expect = 0.027
 Identities = 39/147 (26%), Positives = 65/147 (44%), Gaps = 19/147 (12%)

Query: 76  GPDGRLELKPLLLRLPRICQRNLMSLLMAVRPSLPESGLLSVLQIAQQDLAPD----PDA 131
           GP GRLE        PR   R   SL    R S+    L     +A++++       P A
Sbjct: 355 GPPGRLE------GAPRPVAREKTSLGSLKRASVDVDLLAPRSPMAKENMVTFSHTLPRA 408

Query: 132 WLRALGELLRRDLGVGTSMEGASP---LSERCQRQLQSLCRGLGL----GGRRLKSPQAP 184
              +L +  RR + +   ++ +     +SE  Q+ L+   RGLGL        L++P  P
Sbjct: 409 SAPSLDDPARRHMTIHVPLDASRSKQLISEWKQKSLEG--RGLGLPDDASPGHLRAPAEP 466

Query: 185 DPEEEENRDSQQPGKRRKDSEEEAASP 211
             EEEE  + ++  +  ++ E+E  +P
Sbjct: 467 MAEEEEEEEDEEEEEEEEEEEDEGPAP 493


>gi|149192871 OTU domain containing 3 [Homo sapiens]
          Length = 398

 Score = 37.7 bits (86), Expect = 0.027
 Identities = 28/107 (26%), Positives = 48/107 (44%), Gaps = 2/107 (1%)

Query: 135 ALGELLRRDLGVGTSMEGASPLSERCQRQLQSLCRGLGLGGRRLKSPQAPDPEEEENRDS 194
           A+  +LR + G   + E     S R  +Q   L    G G R   +    +   E N+  
Sbjct: 265 AIIAVLRMNQGKRNNAEENLEPSGRVLKQCGPLWEEGGSGARIFGNQGLNEGRTENNKAQ 324

Query: 195 QQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERPEHKSLES 241
             P +  K ++ + A    K+  +R + W E++  ++ER  HK+LES
Sbjct: 325 ASPSEENKANKNQLAKVTNKQ--RREQQWMEKKKRQEERHRHKALES 369


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score = 37.4 bits (85), Expect = 0.035
 Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 8/84 (9%)

Query: 154 SPLSERCQRQLQSLCRGLGLGGRRLKSPQAPDPEEEENRDSQQPGKRRKDSEEEAASPEG 213
           SP  ER +RQ +S  +       R +S      EE E+R S+ P K R        SP  
Sbjct: 526 SPSKERQRRQSRSPNK------ERDRSQSRSPSEEREHRQSRSPSKER--DRRRWRSPSK 577

Query: 214 KRVPKRLRCWEEEEDHEKERPEHK 237
           +R  ++ R   EE DH + R  +K
Sbjct: 578 ERERRQSRSSSEERDHSRSRSPNK 601



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 8/87 (9%)

Query: 154 SPLSERCQRQLQSLCRGLGLGGRRLKSPQAPDPEEEENRDSQQPGKRRKDSEEEAASPEG 213
           SP  ER  RQ +S  +      RR +SP     +E + R S+ P K R  S+    SP  
Sbjct: 502 SPSKERQCRQSRSSSKERD--HRRSRSPS----KERQRRQSRSPNKERDRSQSR--SPSE 553

Query: 214 KRVPKRLRCWEEEEDHEKERPEHKSLE 240
           +R  ++ R   +E D  + R   K  E
Sbjct: 554 EREHRQSRSPSKERDRRRWRSPSKERE 580


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 37.0 bits (84), Expect = 0.045
 Identities = 35/137 (25%), Positives = 64/137 (46%), Gaps = 17/137 (12%)

Query: 178 LKSPQAPDPEEEENRD--SQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERPE 235
           +KSP+A  P +EE R    + P K +   +EE  SPE  + P +    E+ +  EKE P+
Sbjct: 761 VKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLK----EDAKAPEKEIPK 816

Query: 236 HKSLESLADGGSASPIK-DQPVMAVKTGEDGSNLDDAKGLA--ESLELPKAIQDQLPRLQ 292
            + ++        SP+K ++    VK  E     ++ K  A  ++ E   + +++ P+ +
Sbjct: 817 KEEVK--------SPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKE 868

Query: 293 QLLKTLEEGLEGLEDAP 309
                +EE  E   + P
Sbjct: 869 APKPKVEEKKEPAVEKP 885



 Score = 33.9 bits (76), Expect = 0.38
 Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 9/78 (11%)

Query: 178 LKSPQ-APDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERPEH 236
           +KSP+ A  P +EE   ++ P K +   +EEA SPE  + P +      E+     + E 
Sbjct: 632 VKSPEKAKSPTKEE---AKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEA 688

Query: 237 KSLESLADGGSASPIKDQ 254
           KS E      + SP+K++
Sbjct: 689 KSPEK-----AKSPVKEE 701



 Score = 33.9 bits (76), Expect = 0.38
 Identities = 35/117 (29%), Positives = 59/117 (50%), Gaps = 16/117 (13%)

Query: 179 KSPQ-APDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERPEHK 237
           KSP+ A  P +EE   ++ P K +   +EEA SPE  + P++ +  + +   E + P  +
Sbjct: 717 KSPEKAKSPVKEE---AKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSP-EAKTPAKE 772

Query: 238 SLESLAD---GGSASPIKDQPVMAVKTGEDGSN--LDDAKGLAESLELPKAIQDQLP 289
              S AD     + SP+K++    VK+ E   +   +DAK  A   E+PK  + + P
Sbjct: 773 EARSPADKFPEKAKSPVKEE----VKSPEKAKSPLKEDAK--APEKEIPKKEEVKSP 823



 Score = 32.7 bits (73), Expect = 0.86
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 10/109 (9%)

Query: 174 GGRRLKSP---QAPDPEEEEN----RDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEE 226
           G    KSP   +A  PE+E       +++ P + +   +EEA SP   + P++ +   +E
Sbjct: 497 GEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKE 556

Query: 227 E---DHEKERPEHKSLESLADGGSASPIKDQPVMAVKTGEDGSNLDDAK 272
           E     E + PE +  +S A+  S    K       K+  +  + + AK
Sbjct: 557 EAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAK 605



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 25/78 (32%), Positives = 43/78 (55%), Gaps = 9/78 (11%)

Query: 179 KSP-QAPDPEEEENR---DSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERP 234
           KSP +A  P +EE +   + + P K +  ++EEA SPE  + P++    EE +  EK + 
Sbjct: 613 KSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEK----EEAKSPEKAKS 668

Query: 235 EHKSLESLADGGSASPIK 252
             K+ E+ +   + SP+K
Sbjct: 669 PVKA-EAKSPEKAKSPVK 685



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 6/89 (6%)

Query: 181 PQAPDPEEEENR---DSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEE---DHEKERP 234
           P+A  PE+EE +   + + P K +  ++EEA SP   + P++ +   +EE     E + P
Sbjct: 562 PEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSP 621

Query: 235 EHKSLESLADGGSASPIKDQPVMAVKTGE 263
             +  +S A+  S    K       K+ E
Sbjct: 622 VKEEAKSPAEVKSPEKAKSPTKEEAKSPE 650



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 29/104 (27%), Positives = 51/104 (49%), Gaps = 15/104 (14%)

Query: 177 RLKSP---QAPDPEEEEN---RDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHE 230
           + KSP   +A  PE+ ++    +++ P K +   +EEA SPE  + P +    EE +  E
Sbjct: 665 KAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVK----EEAKSPE 720

Query: 231 KERPEHKSLESLADGGSASPIKDQPVMAVKTGEDGSNLDDAKGL 274
           K +   K  E+     + SP+K++     K+ E   + + AK L
Sbjct: 721 KAKSPVKE-EAKTPEKAKSPVKEE----AKSPEKAKSPEKAKTL 759



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 26/104 (25%), Positives = 45/104 (43%), Gaps = 5/104 (4%)

Query: 151 EGASPLSERCQRQLQSLCRGLGLGGRRLKSPQ-APDPEEEENRDSQQPGKRRKDSEEEAA 209
           E  SP   +   + +S  +         KSP+ A  P +EE   ++ P + +   +EEA 
Sbjct: 571 EAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEE---AKSPAEAKSPVKEEAK 627

Query: 210 SPEGKRVPKRLRCWEEEEDHEKERPEHKSLESLADGGSA-SPIK 252
           SP   + P++ +   +EE    E+ +    E       A SP+K
Sbjct: 628 SPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVK 671



 Score = 29.6 bits (65), Expect = 7.2
 Identities = 21/68 (30%), Positives = 30/68 (44%), Gaps = 2/68 (2%)

Query: 187 EEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERPEHKSLESLADGG 246
           EEEE    ++ GK  +  EEE A  EG     +    EE    EKE       E+ +   
Sbjct: 472 EEEEKEAKEEEGKEEEGGEEEEA--EGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAE 529

Query: 247 SASPIKDQ 254
           + SP K++
Sbjct: 530 AKSPEKEE 537



 Score = 29.3 bits (64), Expect = 9.5
 Identities = 36/152 (23%), Positives = 62/152 (40%), Gaps = 25/152 (16%)

Query: 176 RRLKSPQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERPE 235
           + +K  + P   EEE   +    + +KDS++E A  +    PK     EE+++   E+P+
Sbjct: 831 QEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPK----VEEKKEPAVEKPK 886

Query: 236 HKSLESLADGGS-----ASPIKDQPVMAVKTGEDG----------SNLDDAKGLAESLEL 280
              +E+  +         +P K+ P   V+  ED              DDAK  A+    
Sbjct: 887 ESKVEAKKEEAEDKKKVPTPEKEAPA-KVEVKEDAKPKEKTEVAKKEPDDAK--AKEPSK 943

Query: 281 PKAIQDQLPRLQQLLKTLEEGLEGLEDAPPVE 312
           P   ++  P  +    T EE  +  E+ P  E
Sbjct: 944 PAEKKEAAPEKKD---TKEEKAKKPEEKPKTE 972


>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
          Length = 1233

 Score = 36.6 bits (83), Expect = 0.059
 Identities = 52/188 (27%), Positives = 77/188 (40%), Gaps = 18/188 (9%)

Query: 134 RALGELLRRDLGVGTSMEGASPL--SERCQRQLQSLCRGLGLGG------RRLKSPQAPD 185
           R L E  RR   +    EG  P   +ER  R+ Q   R L   G      R  +  +  +
Sbjct: 258 RRLWEENRRQELLEEEGEGQEPPLEAERAPREEQQ--RSLEAPGWEDAERREREERERLE 315

Query: 186 PEEEENR-DSQQPGKRRKDSEEEAASPEGKRVPKRL-RCWEEEEDHEKERPE-HKSLESL 242
            EEE  R  +Q   + R+  EE+A   E +R  +   RC EE +  E+E  E  + LE  
Sbjct: 316 AEEERRRLQAQAQAEERRRLEEDARLEERRRQEEEEGRCAEELKRQEEEEAEGWEELEQ- 374

Query: 243 ADGGSASPIKDQPVMAVKTGEDGSNLDDAKGLAESLELPKAIQDQLPRLQQLLKTLEEGL 302
                 + ++  P    +TGE     ++     E  E    ++D   +L +LL   EE L
Sbjct: 375 ----QEAEVQGPPEALEETGEGRRGAEEEDLGEEEEEGQAHLEDWRGQLSELLNDFEERL 430

Query: 303 EGLEDAPP 310
           E  E   P
Sbjct: 431 EDQERLKP 438



 Score = 36.2 bits (82), Expect = 0.077
 Identities = 37/139 (26%), Positives = 61/139 (43%), Gaps = 19/139 (13%)

Query: 153  ASPLSERCQRQLQSLCRGLGLGGRRLKSPQAPDPEEEENRDSQQPGKRRKDSEEEAASPE 212
            ASPLS+  +  L  L       GR    P  P  E++E+ D + P             PE
Sbjct: 974  ASPLSKLSRPYLVELLSRRA--GRPDPEPSEPSKEDQESSDRRPPSP---------PGPE 1022

Query: 213  GKRVPKRLRCWEEEEDHEKERPEHKSLESLA-DGGSASPI---KDQPVMAVKTGEDGSNL 268
             ++  KR    +EEE+  + +P    L +   +  S +P    K++P++  +   DGS L
Sbjct: 1023 ERKGQKR----DEEEEATERKPASPPLPATQQEKPSQTPEAGRKEKPMLQSRHSLDGSKL 1078

Query: 269  DDAKGLAESLELPKAIQDQ 287
             +    A+ L +  A+Q Q
Sbjct: 1079 TEKVETAQPLWITLALQKQ 1097


>gi|38569484 kinesin family member 21A [Homo sapiens]
          Length = 1661

 Score = 36.6 bits (83), Expect = 0.059
 Identities = 31/118 (26%), Positives = 50/118 (42%), Gaps = 15/118 (12%)

Query: 188 EEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEE--DHEKERPEHKSLESLADG 245
           +E+N D+ Q  K  K   E        R    L   E +E  DHE E  E +  E   DG
Sbjct: 562 KEDNTDTDQEKKEEKGVSE--------RENNELEVEESQEVSDHEDEEEEEEEEEDDIDG 613

Query: 246 GSASPIKDQPVMAVKTGEDGSNLDDAKGLAESLELPKAIQDQLPRLQQLLKTLEEGLE 303
           G +S   D      ++ E  +   D   +   + + + + D+L   Q+ L+TL++  E
Sbjct: 614 GESSDESDS-----ESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYE 666


>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform b
            [Homo sapiens]
          Length = 1524

 Score = 36.6 bits (83), Expect = 0.059
 Identities = 44/152 (28%), Positives = 60/152 (39%), Gaps = 23/152 (15%)

Query: 176  RRLKSPQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERPE 235
            RRL S Q P  E +E+ +    G   +D E +    EG+          EEE++E E+ E
Sbjct: 1170 RRLSSRQRPSLESDEDVEDSMGG---EDDEVDGDEEEGQ---------SEEEEYEVEQDE 1217

Query: 236  HKSLE----SLADGGSASPIKDQPVMAVKT-GEDGSNLDDAKGLAESLELPKAIQDQLPR 290
              S E    SL   G     + Q  + VKT G+  S+        E    P   Q   P+
Sbjct: 1218 DDSQEEEEVSLPKRG-----RPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPK 1272

Query: 291  LQQLLKTLEEGLEGLEDAPPVELQLLHECSPS 322
                 KT    L  +  APP E + L   S S
Sbjct: 1273 TTVSSKT-GRSLRKINSAPPTETKSLRIASRS 1303


>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform a
            [Homo sapiens]
          Length = 1556

 Score = 36.6 bits (83), Expect = 0.059
 Identities = 44/152 (28%), Positives = 60/152 (39%), Gaps = 23/152 (15%)

Query: 176  RRLKSPQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERPE 235
            RRL S Q P  E +E+ +    G   +D E +    EG+          EEE++E E+ E
Sbjct: 1202 RRLSSRQRPSLESDEDVEDSMGG---EDDEVDGDEEEGQ---------SEEEEYEVEQDE 1249

Query: 236  HKSLE----SLADGGSASPIKDQPVMAVKT-GEDGSNLDDAKGLAESLELPKAIQDQLPR 290
              S E    SL   G     + Q  + VKT G+  S+        E    P   Q   P+
Sbjct: 1250 DDSQEEEEVSLPKRG-----RPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPK 1304

Query: 291  LQQLLKTLEEGLEGLEDAPPVELQLLHECSPS 322
                 KT    L  +  APP E + L   S S
Sbjct: 1305 TTVSSKT-GRSLRKINSAPPTETKSLRIASRS 1335


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 36.6 bits (83), Expect = 0.059
 Identities = 36/158 (22%), Positives = 71/158 (44%), Gaps = 17/158 (10%)

Query: 160 CQRQLQSLCRGLGLGGRRLKSPQAPDPEEEENRDSQQPGKRRKDSE-EEAASPEGKRVPK 218
           C  +L+ L   LG+  ++      P PEE   R+ ++  +R K+ E E+    E +R   
Sbjct: 481 CAEKLKRLDEKLGILEKQ------PSPEEIREREREKEREREKELEKEQEQEREKEREKD 534

Query: 219 RLRCWEEEEDHEKERPEHKSLESLADGGSASPI-----KDQPVMAVKTGEDGSNLDDAKG 273
           R R  E+E++ EKE+ + + +E          +     K++ +  +K  E    L+    
Sbjct: 535 RERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELE---- 590

Query: 274 LAESLELPKAIQDQLPRLQQLLKTLEEGLEGLEDAPPV 311
             E  +L + I+ + P L+ +++  E      ++  PV
Sbjct: 591 -KEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPV 627



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 24/87 (27%), Positives = 37/87 (42%)

Query: 169  RGLGLGGRRLKSPQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEED 228
            RG G  G     PQ  D +         P ++R++SE  + S + + VPKR R    E D
Sbjct: 1207 RGRGGRGHTRDYPQYRDNKPRAEHIPSGPLRQREESETRSESSDFEVVPKRRRQRGSETD 1266

Query: 229  HEKERPEHKSLESLADGGSASPIKDQP 255
             + E  E  S +     G     +++P
Sbjct: 1267 TDSEIHESASDKDSLSKGKLPKREERP 1293


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 36.2 bits (82), Expect = 0.077
 Identities = 20/67 (29%), Positives = 37/67 (55%), Gaps = 1/67 (1%)

Query: 175 GRRLKSPQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDH-EKER 233
           GR  K  +  + +EE  R+ ++  +R+K+  E+    + ++  +R +  E+EE+  EKER
Sbjct: 124 GRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKER 183

Query: 234 PEHKSLE 240
            E K  E
Sbjct: 184 KERKKRE 190



 Score = 29.6 bits (65), Expect = 7.2
 Identities = 16/54 (29%), Positives = 30/54 (55%), Gaps = 1/54 (1%)

Query: 187 EEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERPEHKSLE 240
           E E  ++ ++  KR+++ E+E     GK+  K  R  +EE + +K R E ++ E
Sbjct: 56  ESERKKERREREKRKREREKERKRERGKKEKKGER-KKEERERKKRRREKENKE 108



 Score = 29.3 bits (64), Expect = 9.5
 Identities = 18/52 (34%), Positives = 29/52 (55%), Gaps = 5/52 (9%)

Query: 188 EEENRDSQQPGKRRKDSEEEAA--SPEGKRVPKRLRCWEEEEDHEKERPEHK 237
           E+EN++ ++  KR+K  ++E    S EGK   +R R  E + +  KER   K
Sbjct: 103 EKENKEGEEKEKRKKKEKKERGRTSKEGK---ERERKEERKREERKERERKK 151


>gi|33695153 guanine nucleotide binding protein (G protein), alpha
           activating activity polypeptide, olfactory type isoform
           1 [Homo sapiens]
          Length = 458

 Score = 36.2 bits (82), Expect = 0.077
 Identities = 24/127 (18%), Positives = 58/127 (45%), Gaps = 6/127 (4%)

Query: 172 GLGGRRLKSPQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEK 231
           G G      P+A  P+E+  R  Q   + R+ ++E  A  E ++V + +     ++  + 
Sbjct: 57  GEGSPACARPKADKPKEKRQRTEQLSAEEREAAKEREAVKEARKVSRGIDRMLRDQKRDL 116

Query: 232 ERPEHKSLESLADGGSASPIKDQPVMAVKTGEDGSNLDDAKGLAESLELPKAIQDQLPRL 291
           ++     L    + G ++ +K   ++ V    +G N ++ K   + L++ K ++D +  +
Sbjct: 117 QQTHRLLLLGAGESGKSTIVKQMRILHV----NGFNPEEKK--QKILDIRKNVKDAIVTI 170

Query: 292 QQLLKTL 298
              + T+
Sbjct: 171 VSAMSTI 177


>gi|157042792 coiled-coil domain containing 64B [Homo sapiens]
          Length = 508

 Score = 36.2 bits (82), Expect = 0.077
 Identities = 52/186 (27%), Positives = 81/186 (43%), Gaps = 28/186 (15%)

Query: 134 RALGELLRRDLGVGTSMEGASPLSERCQRQLQSL---CRGLGLGGRRLKSPQAPDPEEEE 190
           RAL EL  ++L +   +  AS   +  QR+L +L   C+   L G  L++       E  
Sbjct: 148 RALSELSEQNLRLSQQLAQASQTEQELQRELDALRGQCQAQALAGAELRTRL-----ESL 202

Query: 191 NRDSQQPGKRRKDSEEE--AASPEGKRVPKRLRCWEEE-EDHEKERPEHKSLE---SLAD 244
             ++Q    RR+D E +      E ++   RL+   EE     +ER EH SLE   + ++
Sbjct: 203 QGENQMLQSRRQDLEAQIRGLREEVEKGEGRLQTTHEELLLLRRERREH-SLELERARSE 261

Query: 245 GGSASPIKDQPVMAVKTGEDGSNLDDAKGLAESLELPKAIQDQLPRLQQLLKTLEEGLEG 304
            G A     +    V   E+ S L DA   A SL+             +L  +L++G +G
Sbjct: 262 AGEALSALRRLQRRVSELEEESRLQDADVSAASLQ------------SELAHSLDDGDQG 309

Query: 305 L-EDAP 309
              DAP
Sbjct: 310 QGADAP 315


>gi|71274144 AT hook, DNA binding motif, containing 1 [Homo sapiens]
          Length = 1603

 Score = 36.2 bits (82), Expect = 0.077
 Identities = 60/208 (28%), Positives = 73/208 (35%), Gaps = 30/208 (14%)

Query: 159 RCQRQLQSLCRGLGLGGRRLKSPQAPDPEEEENRDSQQPGKRRK-DSEEEAASPEGKRVP 217
           R  + LQ     L  GG RL  P AP P + +      P       S EE A+P  K   
Sbjct: 133 RLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSPEERATPHAK--- 189

Query: 218 KRLRCWEEEEDHEKERPEHKSLESLADG-----GSASPIKDQPVMAVKTGEDGSNLDDAK 272
                  E   H    PE +  +S   G     G+ +     P        D S L DA 
Sbjct: 190 ------SERPSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSELADAD 243

Query: 273 GLAE--SLELPKAIQDQLPRLQQLLKTLEEGLEGLEDAPPVELQLLHECSPSQMDLLCAQ 330
            L+E  SL  P+A   QL   Q L     E    L D  P  L       P  ++ L   
Sbjct: 244 ILSELASLTCPEA---QLLEAQALEPPSPEPEPQLLDPQPRFL------DPQALEPLGEA 294

Query: 331 LQLPQL----SDLGLLRLCTWLLALSPD 354
           L+LP L      LGL  L    L   PD
Sbjct: 295 LELPPLQPLADPLGLPGLALQALDTLPD 322


>gi|116256350 tuberous sclerosis 2 isoform 4 [Homo sapiens]
          Length = 1740

 Score = 35.8 bits (81), Expect = 0.10
 Identities = 21/88 (23%), Positives = 39/88 (44%), Gaps = 8/88 (9%)

Query: 63  LLEALCREEPVVQGPDGRLELKPLLLRLPRICQRN--------LMSLLMAVRPSLPESGL 114
           ++E L ++   +  P+ R  +  LL  +  +C +N           L+       PES L
Sbjct: 364 IIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPESSL 423

Query: 115 LSVLQIAQQDLAPDPDAWLRALGELLRR 142
           L+++    Q + P  D W++ L  L+ R
Sbjct: 424 LNLISYRAQSIHPAKDGWIQNLQALMER 451


>gi|116256352 tuberous sclerosis 2 isoform 1 [Homo sapiens]
          Length = 1807

 Score = 35.8 bits (81), Expect = 0.10
 Identities = 21/88 (23%), Positives = 39/88 (44%), Gaps = 8/88 (9%)

Query: 63  LLEALCREEPVVQGPDGRLELKPLLLRLPRICQRN--------LMSLLMAVRPSLPESGL 114
           ++E L ++   +  P+ R  +  LL  +  +C +N           L+       PES L
Sbjct: 364 IIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPESSL 423

Query: 115 LSVLQIAQQDLAPDPDAWLRALGELLRR 142
           L+++    Q + P  D W++ L  L+ R
Sbjct: 424 LNLISYRAQSIHPAKDGWIQNLQALMER 451


>gi|167412124 tuberous sclerosis 2 isoform 5 [Homo sapiens]
          Length = 1784

 Score = 35.8 bits (81), Expect = 0.10
 Identities = 21/88 (23%), Positives = 39/88 (44%), Gaps = 8/88 (9%)

Query: 63  LLEALCREEPVVQGPDGRLELKPLLLRLPRICQRN--------LMSLLMAVRPSLPESGL 114
           ++E L ++   +  P+ R  +  LL  +  +C +N           L+       PES L
Sbjct: 364 IIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPESSL 423

Query: 115 LSVLQIAQQDLAPDPDAWLRALGELLRR 142
           L+++    Q + P  D W++ L  L+ R
Sbjct: 424 LNLISYRAQSIHPAKDGWIQNLQALMER 451


>gi|67188445 CTD (carboxy-terminal domain, RNA polymerase II,
           polypeptide A) phosphatase, subunit 1 isoform FCP1a
           [Homo sapiens]
          Length = 961

 Score = 35.8 bits (81), Expect = 0.10
 Identities = 36/112 (32%), Positives = 46/112 (41%), Gaps = 17/112 (15%)

Query: 149 SMEGASPLSERCQRQLQSLCRG----LGLGGRRLKSPQAPDPEEEENRDSQQPGKRRK-- 202
           SM    PL   C+  L+S+ +     LG G     S +    E+EE    ++PG RR+  
Sbjct: 839 SMSETMPLYTLCKEDLESMDKEVDDILGEGSDDSDSEKRRPEEQEEEPQPRKPGTRRERT 898

Query: 203 -----DSEEEAASPEGKRVPKRLRCWEEEEDHEKERPEHKSLESLADGGSAS 249
                 SE  AA   G R  KR      EED   E     S E   D GS+S
Sbjct: 899 LGAPASSERSAAGGRGPRGHKRKL---NEEDAASESSRESSNE---DEGSSS 944


>gi|239749365 PREDICTED: hypothetical protein XP_002347014 [Homo
           sapiens]
          Length = 190

 Score = 35.8 bits (81), Expect = 0.10
 Identities = 42/155 (27%), Positives = 59/155 (38%), Gaps = 19/155 (12%)

Query: 147 GTSMEGASPLSERCQRQLQSLCRGLGLGGRRLKSPQAPDPEEEENRDSQQPGKRRKDSEE 206
           G S  G SP   RC  +  S  R     G   KSP+ PD +    R  +   +  +   E
Sbjct: 52  GESGAGPSPAWRRCAGEA-SRGRQRARSGPP-KSPRRPDAQLRAARTQRARAQTPQLRRE 109

Query: 207 EAASPEGKRVPKRLRCWEEEEDHEKERPEHKSLESLADGGSASPIKDQPVMAVKTGEDGS 266
           +A + +G         W   E+ +   PE K L  L +GGSA P   +        E G+
Sbjct: 110 DARAGDG---------WPRREEDDVP-PEEKRLRLLLEGGSAQPEDGEDAPRPGREETGT 159

Query: 267 NL-DDAKGLAESLELPKAIQDQLPRLQQLLKTLEE 300
               D KG   S         + PR    L+ +EE
Sbjct: 160 QTGGDGKGAEFSTSF------EQPRFSHPLQIMEE 188


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 35.8 bits (81), Expect = 0.10
 Identities = 21/71 (29%), Positives = 38/71 (53%), Gaps = 3/71 (4%)

Query: 175 GRRLKSPQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERP 234
           G+R +  +    E+E+ + +++  KR++  EEE    + KR  K+ +  EE E+ E+E  
Sbjct: 27  GKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK---KRKRKRKKKKEEEEREEEEEEEE 83

Query: 235 EHKSLESLADG 245
           E K  E   +G
Sbjct: 84  EEKEEEEKEEG 94



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 19/62 (30%), Positives = 31/62 (50%)

Query: 176 RRLKSPQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERPE 235
           ++ K  +    EEEE  + ++  +  K+ EE+      K+  KR R  EEEE  +K R +
Sbjct: 60  KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119

Query: 236 HK 237
            K
Sbjct: 120 TK 121



 Score = 33.9 bits (76), Expect = 0.38
 Identities = 16/62 (25%), Positives = 34/62 (54%)

Query: 179 KSPQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERPEHKS 238
           ++ +  + EEEE ++ ++  KR++  +E+    + K   KR    EEE+  +++R + K 
Sbjct: 12  ETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKE 71

Query: 239 LE 240
            E
Sbjct: 72  EE 73



 Score = 33.5 bits (75), Expect = 0.50
 Identities = 15/58 (25%), Positives = 31/58 (53%)

Query: 176 RRLKSPQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKER 233
           ++ K  +  +  EE   + ++ GKR++  +E+    E K+  K     +E+E+ EK+R
Sbjct: 5   KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 20/73 (27%), Positives = 35/73 (47%), Gaps = 11/73 (15%)

Query: 179 KSPQAPDPEEEENRDSQQPGKRRKDSE-----------EEAASPEGKRVPKRLRCWEEEE 227
           ++ +  + EE+E +  ++  ++RK+ E           +E    E KR  KR +  EEEE
Sbjct: 15  ETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEE 74

Query: 228 DHEKERPEHKSLE 240
             E+E  E +  E
Sbjct: 75  REEEEEEEEEEKE 87


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,173,978
Number of Sequences: 37866
Number of extensions: 1122370
Number of successful extensions: 8542
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 311
Number of HSP's that attempted gapping in prelim test: 7088
Number of HSP's gapped (non-prelim): 1216
length of query: 536
length of database: 18,247,518
effective HSP length: 107
effective length of query: 429
effective length of database: 14,195,856
effective search space: 6090022224
effective search space used: 6090022224
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.