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Search of human proteins with 21361423
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361423 solute carrier family 39 (zinc transporter), member
1 [Homo sapiens]
(324 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361423 solute carrier family 39 (zinc transporter), member ... 630 0.0
gi|32490561 solute carrier family 39 (zinc transporter), member ... 173 2e-43
gi|156415986 solute carrier family 39 (zinc transporter), member... 157 9e-39
gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo... 43 4e-04
gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo... 43 4e-04
gi|117553619 solute carrier family 39, member 7 [Homo sapiens] 43 4e-04
gi|117553608 solute carrier family 39, member 7 [Homo sapiens] 43 4e-04
gi|223633937 solute carrier family 39 (zinc transporter), member... 42 7e-04
gi|223633939 solute carrier family 39 (zinc transporter), member... 42 0.001
gi|40255101 solute carrier family 39 (zinc transporter), member ... 41 0.001
gi|190014617 solute carrier family 39 (zinc transporter), member... 41 0.001
gi|47080103 solute carrier family 39 (zinc transporter), member ... 41 0.002
gi|40254928 solute carrier family 39 (zinc transporter), member ... 40 0.004
gi|10863879 solute carrier family 5 (sodium-dependent vitamin tr... 35 0.069
gi|206597541 solute carrier family 39 (metal ion transporter), m... 35 0.069
gi|206597539 solute carrier family 39 (metal ion transporter), m... 35 0.069
gi|205830405 solute carrier family 39 (zinc transporter), member... 35 0.069
gi|205830424 solute carrier family 39 (zinc transporter), member... 35 0.090
gi|190360568 solute carrier family 39 (zinc transporter), member... 35 0.090
gi|190358541 solute carrier family 39 (zinc transporter), member... 35 0.090
gi|187936949 solute carrier family 39 (zinc transporter), member... 35 0.12
gi|55741750 solute carrier family 39 (zinc transporter), member ... 35 0.12
gi|24586665 solute carrier family 39 (zinc transporter), member ... 33 0.26
gi|205830407 solute carrier family 39 (zinc transporter), member... 33 0.26
gi|205830403 solute carrier family 39 (zinc transporter), member... 33 0.26
gi|45505137 podocan [Homo sapiens] 33 0.45
gi|114796626 solute carrier family 16, member 8 [Homo sapiens] 32 0.77
gi|4505415 NAD(P)H menadione oxidoreductase 1, dioxin-inducible ... 30 2.2
gi|153252201 solute carrier family 39 (zinc transporter), member... 30 2.2
gi|42544153 leukocyte receptor tyrosine kinase isoform 1 precurs... 30 2.2
>gi|21361423 solute carrier family 39 (zinc transporter), member 1
[Homo sapiens]
Length = 324
Score = 630 bits (1624), Expect = 0.0
Identities = 324/324 (100%), Positives = 324/324 (100%)
Query: 1 MGPWGEPELLVWRPEAVASEPPVPVGLEVKLGALVLLLVLTLLCSLVPICVLRRPGANHE 60
MGPWGEPELLVWRPEAVASEPPVPVGLEVKLGALVLLLVLTLLCSLVPICVLRRPGANHE
Sbjct: 1 MGPWGEPELLVWRPEAVASEPPVPVGLEVKLGALVLLLVLTLLCSLVPICVLRRPGANHE 60
Query: 61 GSASRQKALSLVSCFAGGVFLATCLLDLLPDYLAAIDEALAALHVTLQFPLQEFILAMGF 120
GSASRQKALSLVSCFAGGVFLATCLLDLLPDYLAAIDEALAALHVTLQFPLQEFILAMGF
Sbjct: 61 GSASRQKALSLVSCFAGGVFLATCLLDLLPDYLAAIDEALAALHVTLQFPLQEFILAMGF 120
Query: 121 FLVLVMEQITLAYKEQSGPSPLEETRALLGTVNGGPQHWHDGPGVPQASGAPATPSALRA 180
FLVLVMEQITLAYKEQSGPSPLEETRALLGTVNGGPQHWHDGPGVPQASGAPATPSALRA
Sbjct: 121 FLVLVMEQITLAYKEQSGPSPLEETRALLGTVNGGPQHWHDGPGVPQASGAPATPSALRA 180
Query: 181 CVLVFSLALHSVFEGLAVGLQRDRARAMELCLALLLHKGILAVSLSLRLLQSHLRAQVVA 240
CVLVFSLALHSVFEGLAVGLQRDRARAMELCLALLLHKGILAVSLSLRLLQSHLRAQVVA
Sbjct: 181 CVLVFSLALHSVFEGLAVGLQRDRARAMELCLALLLHKGILAVSLSLRLLQSHLRAQVVA 240
Query: 241 GCGILFSCMTPLGIGLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQELASSE 300
GCGILFSCMTPLGIGLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQELASSE
Sbjct: 241 GCGILFSCMTPLGIGLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQELASSE 300
Query: 301 QRILKVILLLAGFALLTGLLFIQI 324
QRILKVILLLAGFALLTGLLFIQI
Sbjct: 301 QRILKVILLLAGFALLTGLLFIQI 324
>gi|32490561 solute carrier family 39 (zinc transporter), member 3
isoform a [Homo sapiens]
Length = 314
Score = 173 bits (438), Expect = 2e-43
Identities = 106/315 (33%), Positives = 173/315 (54%), Gaps = 24/315 (7%)
Query: 27 LEVKLGALVLLLVLTLLCSLVPICVLRRPGANHEGSASRQKALSLVSCFAGGVFLATCLL 86
L K+ +V + LL SL+P+ ++ + E + +K LSL + F GGVFLATC
Sbjct: 5 LVAKILCMVGVFFFMLLGSLLPVKIIE---TDFEKAHRSKKILSLCNTFGGGVFLATCFN 61
Query: 87 DLLPDYLAAIDEALAALHVTLQFPLQEFILAMGFFLVLVMEQITLAYKEQSGP------- 139
LLP + + L+ H++ +PL E IL +GFF+ + +EQ+ L ++++
Sbjct: 62 ALLPAVREKLQKVLSLGHISTDYPLAETILLLGFFMTVFLEQLILTFRKEKPSFIDLETF 121
Query: 140 -------SPLEETRALLGTVNGGP----QHWHDGPGVPQASGAPATPSALRACVLVFSLA 188
S E +G G H H GP + + A+P +R L F+L+
Sbjct: 122 NAGSDVGSDSEYESPFMGGARGHALYVEPHGH-GPSLSVQGLSRASP--VRLLSLAFALS 178
Query: 189 LHSVFEGLAVGLQRDRARAMELCLALLLHKGILAVSLSLRLLQSHLRAQVVAGCGILFSC 248
HSVFEGLA+GLQ + + + L + + +H+ ++AV+L + + +S + + A + S
Sbjct: 179 AHSVFEGLALGLQEEGEKVVSLFVGVAVHETLVAVALGISMARSAMPLRDAAKLAVTVSA 238
Query: 249 MTPLGIGLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQELASSEQRILKVIL 308
M PLGIGLG + + G +A +L+G+A GTFL+ITFLEIL +EL R+LKV+
Sbjct: 239 MIPLGIGLGLGIESAQGVPGSVASVLLQGLAGGTFLFITFLEILAKELEEKSDRLLKVLF 298
Query: 309 LLAGFALLTGLLFIQ 323
L+ G+ +L G++F++
Sbjct: 299 LVLGYTVLAGMVFLK 313
>gi|156415986 solute carrier family 39 (zinc transporter), member 2
[Homo sapiens]
Length = 309
Score = 157 bits (398), Expect = 9e-39
Identities = 111/310 (35%), Positives = 161/310 (51%), Gaps = 32/310 (10%)
Query: 27 LEVKLGALVLLLVLTLLCSLVPICVLRRPGANHEGSASRQKALSLVSCFAGGVFLATCLL 86
L +KLG L LL LTL C L PIC + + L L+ C + GVFL +
Sbjct: 5 LGIKLGCLFALLALTLGCGLTPICF--KWFQIDAARGHHRLVLRLLGCISAGVFLGAGFM 62
Query: 87 DLLPDYLAAIDEALAALHVT-----------------LQFPLQEFILAMGFFLVLVMEQI 129
+ + L I+ + V +++P E I+++GFF V +E +
Sbjct: 63 HMTAEALEEIESQIQKFMVQNRSASERNSSGDADSAHMEYPYGELIISLGFFFVFFLESL 122
Query: 130 TL-AYKEQSGPSPLEETRALLGTVNGGPQHWHDGPGVPQASGAPATPSALRACVLVFSLA 188
L +G S +++ + H H +P S P LRA VL+ SL+
Sbjct: 123 ALQCCPGAAGGSTVQDEEWGGAHIFELHSHGH----LPSPSKGP-----LRALVLLLSLS 173
Query: 189 LHSVFEGLAVGLQRDRARAMELCLALLLHKGILAVSLSLRLLQSHLRAQVVAGCGILFSC 248
HSVFEGLAVGLQ A ++LCLA+L HKG++ + +RL+ ++ +L +
Sbjct: 174 FHSVFEGLAVGLQPTVAATVQLCLAVLAHKGLVVFGVGMRLVHLGTSSRWAVFSILLLAL 233
Query: 249 MTPLGIGLGAAL--AESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQELASSEQRILKV 306
M+PLG+ +G A+ +S G LAQ+VLEG+AAGTFLY+TFLEILP+ELAS E + K
Sbjct: 234 MSPLGLAVGLAVTGGDSEGG-RGLAQAVLEGVAAGTFLYVTFLEILPRELASPEAPLAKW 292
Query: 307 ILLLAGFALL 316
+ AGFA +
Sbjct: 293 SCVAAGFAFM 302
>gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo
sapiens]
Length = 342
Score = 42.7 bits (99), Expect = 4e-04
Identities = 48/174 (27%), Positives = 74/174 (42%), Gaps = 22/174 (12%)
Query: 161 DGPGVPQAS----GAPATPSALRACVLVFSLALHSVFEGLAVG-----LQRDRARAMELC 211
+GP VP S P S R +L+ ++ +H+V EGLAVG +++ + E
Sbjct: 171 EGPAVPVPSRGNLAQPGGSSWRRIALLILAITIHNVPEGLAVGVGFGAIEKTASATFESA 230
Query: 212 LALLLHKGI------LAVSLSLRLLQSHLRAQVVAGCGILFSCMTPLGIGLGAALAESAG 265
L + GI LAVSL LR + G L + PL GA A
Sbjct: 231 RNLAIGIGIQNFPEGLAVSLPLR--GAGFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAE 288
Query: 266 PLHQLAQSVLEGMAAGTFLYITFLEILPQELASSEQRILKVILLLAGFALLTGL 319
P+ A + AAG +Y+ +I+P+ S ++ +L GF ++ L
Sbjct: 289 PILPYALA----FAAGAMVYVVMDDIIPEAQISGNGKLASWASIL-GFVVMMSL 337
>gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo
sapiens]
Length = 335
Score = 42.7 bits (99), Expect = 4e-04
Identities = 48/174 (27%), Positives = 74/174 (42%), Gaps = 22/174 (12%)
Query: 161 DGPGVPQAS----GAPATPSALRACVLVFSLALHSVFEGLAVG-----LQRDRARAMELC 211
+GP VP S P S R +L+ ++ +H+V EGLAVG +++ + E
Sbjct: 164 EGPAVPVPSRGNLAQPGGSSWRRIALLILAITIHNVPEGLAVGVGFGAIEKTASATFESA 223
Query: 212 LALLLHKGI------LAVSLSLRLLQSHLRAQVVAGCGILFSCMTPLGIGLGAALAESAG 265
L + GI LAVSL LR + G L + PL GA A
Sbjct: 224 RNLAIGIGIQNFPEGLAVSLPLR--GAGFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAE 281
Query: 266 PLHQLAQSVLEGMAAGTFLYITFLEILPQELASSEQRILKVILLLAGFALLTGL 319
P+ A + AAG +Y+ +I+P+ S ++ +L GF ++ L
Sbjct: 282 PILPYALA----FAAGAMVYVVMDDIIPEAQISGNGKLASWASIL-GFVVMMSL 330
>gi|117553619 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 42.7 bits (99), Expect = 4e-04
Identities = 55/198 (27%), Positives = 86/198 (43%), Gaps = 22/198 (11%)
Query: 134 KEQSGPSPLEETRALLGTVNGGPQHWHDGPGVPQASGAPATPSALRACVLVFSLA--LHS 191
++QS +ETR + GG DGP PQ + LR + A H+
Sbjct: 272 EKQSSEEEEKETRGVQKR-RGGSTVPKDGPVRPQNAEEEKRGLDLRVSGYLNLAADLAHN 330
Query: 192 VFEGLAVGLQRDRARAMELC--LALLLHKGILAVSLSLRLLQSH------LRAQVVAGCG 243
+GLA+G R + + + +LLH+ V L+QS +R Q++ G
Sbjct: 331 FTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVG 390
Query: 244 ILFSCMTPL---GIGLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQEL--AS 298
L L G +G+ +A AGP L AG F+Y+ + +LP+ L AS
Sbjct: 391 ALAGTACALLTEGGAVGSEIAGGAGPGWVLP------FTAGGFIYVATVSVLPELLREAS 444
Query: 299 SEQRILKVILLLAGFALL 316
Q +L+V+ LL G ++
Sbjct: 445 PLQSLLEVLGLLGGVIMM 462
>gi|117553608 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 42.7 bits (99), Expect = 4e-04
Identities = 55/198 (27%), Positives = 86/198 (43%), Gaps = 22/198 (11%)
Query: 134 KEQSGPSPLEETRALLGTVNGGPQHWHDGPGVPQASGAPATPSALRACVLVFSLA--LHS 191
++QS +ETR + GG DGP PQ + LR + A H+
Sbjct: 272 EKQSSEEEEKETRGVQKR-RGGSTVPKDGPVRPQNAEEEKRGLDLRVSGYLNLAADLAHN 330
Query: 192 VFEGLAVGLQRDRARAMELC--LALLLHKGILAVSLSLRLLQSH------LRAQVVAGCG 243
+GLA+G R + + + +LLH+ V L+QS +R Q++ G
Sbjct: 331 FTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVG 390
Query: 244 ILFSCMTPL---GIGLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQEL--AS 298
L L G +G+ +A AGP L AG F+Y+ + +LP+ L AS
Sbjct: 391 ALAGTACALLTEGGAVGSEIAGGAGPGWVLP------FTAGGFIYVATVSVLPELLREAS 444
Query: 299 SEQRILKVILLLAGFALL 316
Q +L+V+ LL G ++
Sbjct: 445 PLQSLLEVLGLLGGVIMM 462
>gi|223633937 solute carrier family 39 (zinc transporter), member 12
isoform 2 [Homo sapiens]
Length = 654
Score = 42.0 bits (97), Expect = 7e-04
Identities = 47/204 (23%), Positives = 86/204 (42%), Gaps = 22/204 (10%)
Query: 119 GFFLVLVMEQITLAYKEQSGPSPLEETRALLGTVNGGPQHWHDGPGVPQASGAPATPSAL 178
GFFL+ + ++ ++ P + +G++ AS +L
Sbjct: 457 GFFLIEKCFILLVSPNDKKSPEDSQAAEMPIGSMT--------------ASNRKCKAISL 502
Query: 179 RACVLVFSLALHSVFEGLAVG--LQRDRARAMELCLALLLHKGILAVSLSLRLLQSHLRA 236
A +++ +LH+ +GLA+G + +A+L H+ + LL S L
Sbjct: 503 LAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSM 562
Query: 237 QVVAGCGILFSCMTPLGIGLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQEL 296
+ + S +G+ +G L+ SA P Q + + AG FLY++ +E+LP+
Sbjct: 563 KTAILMNFISSLTAFMGLYIG--LSVSADPC---VQDWIFTVTAGMFLYLSLVEMLPEMT 617
Query: 297 ASSEQRILKVILLLAGFALLTGLL 320
QR ++ LL F L+ G L
Sbjct: 618 HVQTQRPW-MMFLLQNFGLILGWL 640
>gi|223633939 solute carrier family 39 (zinc transporter), member 12
isoform 1 [Homo sapiens]
Length = 691
Score = 41.6 bits (96), Expect = 0.001
Identities = 42/159 (26%), Positives = 71/159 (44%), Gaps = 8/159 (5%)
Query: 164 GVPQASGAPATPSALRACVLVFSLALHSVFEGLAVG--LQRDRARAMELCLALLLHKGIL 221
G AS +L A +++ +LH+ +GLA+G + +A+L H+
Sbjct: 525 GSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPH 584
Query: 222 AVSLSLRLLQSHLRAQVVAGCGILFSCMTPLGIGLGAALAESAGPLHQLAQSVLEGMAAG 281
+ LL S L + + S +G+ +G L+ SA P Q + + AG
Sbjct: 585 EMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIG--LSVSADPC---VQDWIFTVTAG 639
Query: 282 TFLYITFLEILPQELASSEQRILKVILLLAGFALLTGLL 320
FLY++ +E+LP+ QR ++ LL F L+ G L
Sbjct: 640 MFLYLSLVEMLPEMTHVQTQRPW-MMFLLQNFGLILGWL 677
>gi|40255101 solute carrier family 39 (zinc transporter), member 13
isoform b [Homo sapiens]
Length = 364
Score = 41.2 bits (95), Expect = 0.001
Identities = 62/253 (24%), Positives = 105/253 (41%), Gaps = 19/253 (7%)
Query: 75 FAGGVFLATCLLDLLPD---YLAAIDEALAALHVTLQFPLQEFILAMGFFLVLVMEQITL 131
FA G L L LLP+ Y + + Q L +++A G L +E++ L
Sbjct: 112 FALGGLLGNVFLHLLPEAWAYTCSASPGGEGQSLQQQQQLGLWVIA-GILTFLALEKMFL 170
Query: 132 AYKEQ-SGPSPLEETRALLGTVNGGPQHWHDGPGVPQASGAPATPSALRACVLVFSLALH 190
KE+ + +P ++ A +NGG H P GA + + + + +
Sbjct: 171 DSKEEGTSQAPNKDPTAAAAALNGG--HCLAQPAAEPGLGAVVRSIKVSGYLNLLANTID 228
Query: 191 SVFEGLAVGLQRDRARAMELC--LALLLHKGILAVSLSLRLLQSHLRAQVVAGCGILFSC 248
+ GLAV ++ + L +A+LLH+ + + LRA
Sbjct: 229 NFTHGLAVAASFLVSKKIGLLTTMAILLHE----IPHEVGDFAILLRAGFDRWSAAKLQL 284
Query: 249 MTPLGIGLGAALA---ESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQELASSE--QRI 303
T LG LGA A +S + + A VL +G FLYI + +LP L + + +
Sbjct: 285 STALGGLLGAGFAICTQSPKGVEETAAWVLP-FTSGGFLYIALVNVLPDLLEEEDPWRSL 343
Query: 304 LKVILLLAGFALL 316
+++LL AG ++
Sbjct: 344 QQLLLLCAGIVVM 356
>gi|190014617 solute carrier family 39 (zinc transporter), member 13
isoform a [Homo sapiens]
Length = 371
Score = 41.2 bits (95), Expect = 0.001
Identities = 62/263 (23%), Positives = 107/263 (40%), Gaps = 32/263 (12%)
Query: 75 FAGGVFLATCLLDLLPD---YLAAIDEALAALHVTLQFPLQEFILAMGFFLVLVMEQITL 131
FA G L L LLP+ Y + + Q L +++A G L +E++ L
Sbjct: 112 FALGGLLGNVFLHLLPEAWAYTCSASPGGEGQSLQQQQQLGLWVIA-GILTFLALEKMFL 170
Query: 132 AYKEQ-SGPSPLEETRALLGTVNGGPQHWHDGPGVPQASGAPATPSALRACVLVFSLALH 190
KE+ + +P ++ A +NGG H P GA + + + + +
Sbjct: 171 DSKEEGTSQAPNKDPTAAAAALNGG--HCLAQPAAEPGLGAVVRSIKVSGYLNLLANTID 228
Query: 191 SVFEGLAVGLQRDRARAMELC--LALLLHK-----GILAVSL-------SLRLLQSHLRA 236
+ GLAV ++ + L +A+LLH+ G A+ L S LQ
Sbjct: 229 NFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLSTAL 288
Query: 237 QVVAGCGILFSCMTPLGI-GLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQE 295
+ G G +P G+ G A E+A + + +G FLYI + +LP
Sbjct: 289 GGLLGAGFAICTQSPKGVVGCSPAAEETA--------AWVLPFTSGGFLYIALVNVLPDL 340
Query: 296 LASSE--QRILKVILLLAGFALL 316
L + + + +++LL AG ++
Sbjct: 341 LEEEDPWRSLQQLLLLCAGIVVM 363
>gi|47080103 solute carrier family 39 (zinc transporter), member 3
isoform b [Homo sapiens]
Length = 105
Score = 40.8 bits (94), Expect = 0.002
Identities = 25/64 (39%), Positives = 36/64 (56%), Gaps = 3/64 (4%)
Query: 27 LEVKLGALVLLLVLTLLCSLVPICVLRRPGANHEGSASRQKALSLVSCFAGGVFLATCLL 86
L K+ +V + LL SL+P+ ++ + E + +K LSL + F GGVFLATC
Sbjct: 5 LVAKILCMVGVFFFMLLGSLLPVKIIE---TDFEKAHRSKKILSLCNTFGGGVFLATCFN 61
Query: 87 DLLP 90
LLP
Sbjct: 62 ALLP 65
>gi|40254928 solute carrier family 39 (zinc transporter), member 9
[Homo sapiens]
Length = 307
Score = 39.7 bits (91), Expect = 0.004
Identities = 33/155 (21%), Positives = 70/155 (45%), Gaps = 18/155 (11%)
Query: 148 LLGTVNGGPQHWHDGPGVPQASGAPATPSALRACVLVFSLALHSVFEGLAVGLQRDRARA 207
L+ + H D P ++S + T + L +H+ +G+A+G ++
Sbjct: 121 LVDQIGNSHVHSTDDPEAARSSNSKITTT--------LGLVVHAAADGVALGAAASTSQT 172
Query: 208 ---MELCLALLLHKGILAVSLSLRLLQSHLRAQVVAGCGILFSCMTPLG-----IGLGAA 259
+ + +A++LHK A L L+ + L + ++F+ P+ +GL +
Sbjct: 173 SVQLIVFVAIMLHKAPAAFGLVSFLMHAGLERNRIRKHLLVFALAAPVMSMVTYLGLSKS 232
Query: 260 LAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQ 294
E+ ++ ++L +AGTFLY+ + +LP+
Sbjct: 233 SKEALSEVNATGVAML--FSAGTFLYVATVHVLPE 265
>gi|10863879 solute carrier family 5 (sodium-dependent vitamin
transporter), member 6 [Homo sapiens]
Length = 635
Score = 35.4 bits (80), Expect = 0.069
Identities = 55/215 (25%), Positives = 83/215 (38%), Gaps = 43/215 (20%)
Query: 77 GGVFLATCLLDL----LPDYLAAIDEALAALHVTLQFPLQEFILAMGFFLVLVMEQITLA 132
GGVF+ L + + YL++ E A L FP Q+ L +G + LVM A
Sbjct: 262 GGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAVFPFQQVSLCVGCLIGLVM----FA 317
Query: 133 YKEQSGPSPLEETRALLGTVNGGPQHWHDGPGVPQASGAPATPSALRACVLVFSLA-LHS 191
Y Q P +++ +A P + + G P P AC+ SL+ + S
Sbjct: 318 Y-YQEYPMSIQQAQA-------APDQFVLYFVMDLLKGLPGLPGLFIACLFSGSLSTISS 369
Query: 192 VFEGLAVGLQRD----------RARAMELCLALLLHKGILAVSLSL------RLLQSHLR 235
F LA D ARA+ L L G+L + ++ +LQ+ +
Sbjct: 370 AFNSLATVTMEDLIRPWFPEFSEARAIMLSRGLAFGYGLLCLGMAYISSQMGPVLQAAIS 429
Query: 236 AQVVAG--------CGILFSCMTPLG--IGLGAAL 260
+ G G+ F C P G +GL A L
Sbjct: 430 IFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGL 464
>gi|206597541 solute carrier family 39 (metal ion transporter),
member 5 [Homo sapiens]
Length = 540
Score = 35.4 bits (80), Expect = 0.069
Identities = 36/132 (27%), Positives = 59/132 (44%), Gaps = 7/132 (5%)
Query: 189 LHSVFEGLAVG--LQRDRARAMELCLALLLHKGILAVSLSLRLLQSHLRAQVVAGCGILF 246
LH++ +GLA+G + + LA+ H+ + LLQS L + + ++
Sbjct: 393 LHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGLSFRRLLLLSLVS 452
Query: 247 SCMTPLGIGLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQELASSEQRILKV 306
+ G LG L+ PL + G+ AG FLY+ +++LP L E +
Sbjct: 453 GALGLGGAVLGVGLSLGPVPLTPW----VFGVTAGVFLYVALVDMLPALLRPPEP-LPTP 507
Query: 307 ILLLAGFALLTG 318
+LL G LL G
Sbjct: 508 HVLLQGLGLLLG 519
>gi|206597539 solute carrier family 39 (metal ion transporter),
member 5 [Homo sapiens]
Length = 540
Score = 35.4 bits (80), Expect = 0.069
Identities = 36/132 (27%), Positives = 59/132 (44%), Gaps = 7/132 (5%)
Query: 189 LHSVFEGLAVG--LQRDRARAMELCLALLLHKGILAVSLSLRLLQSHLRAQVVAGCGILF 246
LH++ +GLA+G + + LA+ H+ + LLQS L + + ++
Sbjct: 393 LHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGLSFRRLLLLSLVS 452
Query: 247 SCMTPLGIGLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQELASSEQRILKV 306
+ G LG L+ PL + G+ AG FLY+ +++LP L E +
Sbjct: 453 GALGLGGAVLGVGLSLGPVPLTPW----VFGVTAGVFLYVALVDMLPALLRPPEP-LPTP 507
Query: 307 ILLLAGFALLTG 318
+LL G LL G
Sbjct: 508 HVLLQGLGLLLG 519
>gi|205830405 solute carrier family 39 (zinc transporter), member 8
isoform b [Homo sapiens]
Length = 444
Score = 35.4 bits (80), Expect = 0.069
Identities = 25/120 (20%), Positives = 55/120 (45%), Gaps = 8/120 (6%)
Query: 188 ALHSVFEGLAVGLQRDRA--RAMELCLALLLHKGILAVSLSLRLLQSHLRAQVVAGCGIL 245
ALH+ +GLA+G + + + +A+L + + + LL + + + L
Sbjct: 312 ALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFL 371
Query: 246 FSCMTPLGIGLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQELASSEQRILK 305
+C +G+ G + + P +++ +A G FLYI+ ++ P+ ++I+K
Sbjct: 372 SACSCYVGLAFGILVGNNFAP------NIIFALAGGMFLYISLADMFPEMNDMLREKIIK 425
>gi|205830424 solute carrier family 39 (zinc transporter), member 14
isoform a [Homo sapiens]
Length = 492
Score = 35.0 bits (79), Expect = 0.090
Identities = 34/151 (22%), Positives = 69/151 (45%), Gaps = 12/151 (7%)
Query: 180 ACVLVFSLALHSVFEGLAVGLQRDRA--RAMELCLALLLHKGILAVSLSLRLLQSHLRAQ 237
A ++ S LH+ +GLA+G + + + +A+L + + + LL + + Q
Sbjct: 337 AWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQ 396
Query: 238 VVAGCGILFSCMTPLGIGLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQ--E 295
L +C LG+ G LA S + + + +A G FLYI+ ++ P+ E
Sbjct: 397 QALFFNFLSACCCYLGLAFGI-LAGS-----HFSANWIFALAGGMFLYISLADMFPEMNE 450
Query: 296 LASSEQRILKVIL--LLAGFALLTGLLFIQI 324
+ ++R +++ ++ LLTG + +
Sbjct: 451 VCQEDERKGSILIPFIIQNLGLLTGFTIMVV 481
Score = 28.5 bits (62), Expect = 8.5
Identities = 15/55 (27%), Positives = 26/55 (47%)
Query: 72 VSCFAGGVFLATCLLDLLPDYLAAIDEALAALHVTLQFPLQEFILAMGFFLVLVM 126
+ AGG+FL L D+ P+ E + + F +Q L GF +++V+
Sbjct: 428 IFALAGGMFLYISLADMFPEMNEVCQEDERKGSILIPFIIQNLGLLTGFTIMVVL 482
>gi|190360568 solute carrier family 39 (zinc transporter), member 14
isoform a [Homo sapiens]
Length = 492
Score = 35.0 bits (79), Expect = 0.090
Identities = 34/151 (22%), Positives = 69/151 (45%), Gaps = 12/151 (7%)
Query: 180 ACVLVFSLALHSVFEGLAVGLQRDRA--RAMELCLALLLHKGILAVSLSLRLLQSHLRAQ 237
A ++ S LH+ +GLA+G + + + +A+L + + + LL + + Q
Sbjct: 337 AWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQ 396
Query: 238 VVAGCGILFSCMTPLGIGLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQ--E 295
L +C LG+ G LA S + + + +A G FLYI+ ++ P+ E
Sbjct: 397 QALFFNFLSACCCYLGLAFGI-LAGS-----HFSANWIFALAGGMFLYISLADMFPEMNE 450
Query: 296 LASSEQRILKVIL--LLAGFALLTGLLFIQI 324
+ ++R +++ ++ LLTG + +
Sbjct: 451 VCQEDERKGSILIPFIIQNLGLLTGFTIMVV 481
Score = 28.5 bits (62), Expect = 8.5
Identities = 15/55 (27%), Positives = 26/55 (47%)
Query: 72 VSCFAGGVFLATCLLDLLPDYLAAIDEALAALHVTLQFPLQEFILAMGFFLVLVM 126
+ AGG+FL L D+ P+ E + + F +Q L GF +++V+
Sbjct: 428 IFALAGGMFLYISLADMFPEMNEVCQEDERKGSILIPFIIQNLGLLTGFTIMVVL 482
>gi|190358541 solute carrier family 39 (zinc transporter), member 14
isoform b [Homo sapiens]
Length = 492
Score = 35.0 bits (79), Expect = 0.090
Identities = 34/151 (22%), Positives = 69/151 (45%), Gaps = 12/151 (7%)
Query: 180 ACVLVFSLALHSVFEGLAVGLQRDRA--RAMELCLALLLHKGILAVSLSLRLLQSHLRAQ 237
A ++ S LH+ +GLA+G + + + +A+L + + + LL + + Q
Sbjct: 337 AWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQ 396
Query: 238 VVAGCGILFSCMTPLGIGLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQ--E 295
L +C LG+ G LA S + + + +A G FLYI+ ++ P+ E
Sbjct: 397 QALFFNFLSACCCYLGLAFGI-LAGS-----HFSANWIFALAGGMFLYISLADMFPEMNE 450
Query: 296 LASSEQRILKVIL--LLAGFALLTGLLFIQI 324
+ ++R +++ ++ LLTG + +
Sbjct: 451 VCQEDERKGSILIPFIIQNLGLLTGFTIMVV 481
Score = 28.5 bits (62), Expect = 8.5
Identities = 15/55 (27%), Positives = 26/55 (47%)
Query: 72 VSCFAGGVFLATCLLDLLPDYLAAIDEALAALHVTLQFPLQEFILAMGFFLVLVM 126
+ AGG+FL L D+ P+ E + + F +Q L GF +++V+
Sbjct: 428 IFALAGGMFLYISLADMFPEMNEVCQEDERKGSILIPFIIQNLGLLTGFTIMVVL 482
>gi|187936949 solute carrier family 39 (zinc transporter), member 10
[Homo sapiens]
Length = 831
Score = 34.7 bits (78), Expect = 0.12
Identities = 39/175 (22%), Positives = 77/175 (44%), Gaps = 20/175 (11%)
Query: 157 QHWHDGPGVPQASGAPATPSALR--ACVLVFSLALHSVFEGLAVG--LQRDRARAMELCL 212
+H H G P SG+ + + A +++ +H+ +GLA+G + +
Sbjct: 646 KHSHHSHG-PCHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSI 704
Query: 213 ALLLHKGILAVSLSLRLLQSHLRAQVVAGCGILFSCMTPLGIGLGAALAESAGPLHQLAQ 272
A+ H+ + LL++ + + +L + M +G+ +G A+ + A +
Sbjct: 705 AVFCHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIF 764
Query: 273 SVLEGMAAGTFLYITFLEILPQELASS-----------EQRILKVILLLAGFALL 316
+V GM FLY+ +++LP+ L Q IL+ + LL GFA++
Sbjct: 765 AVTAGM----FLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIM 815
>gi|55741750 solute carrier family 39 (zinc transporter), member 10
[Homo sapiens]
Length = 831
Score = 34.7 bits (78), Expect = 0.12
Identities = 39/175 (22%), Positives = 77/175 (44%), Gaps = 20/175 (11%)
Query: 157 QHWHDGPGVPQASGAPATPSALR--ACVLVFSLALHSVFEGLAVG--LQRDRARAMELCL 212
+H H G P SG+ + + A +++ +H+ +GLA+G + +
Sbjct: 646 KHSHHSHG-PCHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSI 704
Query: 213 ALLLHKGILAVSLSLRLLQSHLRAQVVAGCGILFSCMTPLGIGLGAALAESAGPLHQLAQ 272
A+ H+ + LL++ + + +L + M +G+ +G A+ + A +
Sbjct: 705 AVFCHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIF 764
Query: 273 SVLEGMAAGTFLYITFLEILPQELASS-----------EQRILKVILLLAGFALL 316
+V GM FLY+ +++LP+ L Q IL+ + LL GFA++
Sbjct: 765 AVTAGM----FLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIM 815
>gi|24586665 solute carrier family 39 (zinc transporter), member 8
isoform a [Homo sapiens]
Length = 460
Score = 33.5 bits (75), Expect = 0.26
Identities = 23/109 (21%), Positives = 50/109 (45%), Gaps = 8/109 (7%)
Query: 188 ALHSVFEGLAVGLQRDRA--RAMELCLALLLHKGILAVSLSLRLLQSHLRAQVVAGCGIL 245
ALH+ +GLA+G + + + +A+L + + + LL + + + L
Sbjct: 312 ALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFL 371
Query: 246 FSCMTPLGIGLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQ 294
+C +G+ G + + P +++ +A G FLYI+ ++ P+
Sbjct: 372 SACSCYVGLAFGILVGNNFAP------NIIFALAGGMFLYISLADMFPE 414
>gi|205830407 solute carrier family 39 (zinc transporter), member 8
isoform c [Homo sapiens]
Length = 393
Score = 33.5 bits (75), Expect = 0.26
Identities = 23/109 (21%), Positives = 50/109 (45%), Gaps = 8/109 (7%)
Query: 188 ALHSVFEGLAVGLQRDRA--RAMELCLALLLHKGILAVSLSLRLLQSHLRAQVVAGCGIL 245
ALH+ +GLA+G + + + +A+L + + + LL + + + L
Sbjct: 245 ALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFL 304
Query: 246 FSCMTPLGIGLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQ 294
+C +G+ G + + P +++ +A G FLYI+ ++ P+
Sbjct: 305 SACSCYVGLAFGILVGNNFAP------NIIFALAGGMFLYISLADMFPE 347
>gi|205830403 solute carrier family 39 (zinc transporter), member 8
isoform a [Homo sapiens]
Length = 460
Score = 33.5 bits (75), Expect = 0.26
Identities = 23/109 (21%), Positives = 50/109 (45%), Gaps = 8/109 (7%)
Query: 188 ALHSVFEGLAVGLQRDRA--RAMELCLALLLHKGILAVSLSLRLLQSHLRAQVVAGCGIL 245
ALH+ +GLA+G + + + +A+L + + + LL + + + L
Sbjct: 312 ALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFL 371
Query: 246 FSCMTPLGIGLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQ 294
+C +G+ G + + P +++ +A G FLYI+ ++ P+
Sbjct: 372 SACSCYVGLAFGILVGNNFAP------NIIFALAGGMFLYISLADMFPE 414
>gi|45505137 podocan [Homo sapiens]
Length = 661
Score = 32.7 bits (73), Expect = 0.45
Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 2/53 (3%)
Query: 12 WRPEAVASEPPVPVGLEVKLGALVLLLVLTLLCSLVPICVLRRPGANHEGSAS 64
WRP A S PP G + L+LLL+L L P+ +R PG G S
Sbjct: 35 WRPGASDSAPPA--GTMAQSRVLLLLLLLPPQLHLGPVLAVRAPGFGRSGGHS 85
>gi|114796626 solute carrier family 16, member 8 [Homo sapiens]
Length = 504
Score = 32.0 bits (71), Expect = 0.77
Identities = 35/115 (30%), Positives = 52/115 (45%), Gaps = 15/115 (13%)
Query: 206 RAMELCLALLLHKGILAVSLSLRLLQSHLRAQVVAGCGILFSCMTPLGIGLGAALAESAG 265
R + L LL G++ S + RLL+ +L A V+ G G+ + P I LG
Sbjct: 85 RPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALN-FQPSLIMLGLYFERRRP 143
Query: 266 PLHQLAQSVLEGMAAGTFLYITFLEILPQELASSEQRILKVILLLAGFALLTGLL 320
+ LA AAG+ ++++ L L Q+L L+ GF LL GLL
Sbjct: 144 LANGLA-------AAGSPVFLSALSPLGQQL-------LERFGWRGGFLLLGGLL 184
>gi|4505415 NAD(P)H menadione oxidoreductase 1, dioxin-inducible
isoform a [Homo sapiens]
Length = 274
Score = 30.4 bits (67), Expect = 2.2
Identities = 22/81 (27%), Positives = 33/81 (40%), Gaps = 3/81 (3%)
Query: 88 LLPDYLAAIDEALAALHVTLQFPLQEF---ILAMGFFLVLVMEQITLAYKEQSGPSPLEE 144
L PD +A + AA V QFPLQ F + G+F + + + Y P
Sbjct: 81 LSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERVFIGEFAYTYAAMYDKGPFRS 140
Query: 145 TRALLGTVNGGPQHWHDGPGV 165
+A+L GG + G+
Sbjct: 141 KKAVLSITTGGSGSMYSLQGI 161
>gi|153252201 solute carrier family 39 (zinc transporter), member 6
isoform 1 [Homo sapiens]
Length = 755
Score = 30.4 bits (67), Expect = 2.2
Identities = 24/122 (19%), Positives = 54/122 (44%), Gaps = 6/122 (4%)
Query: 177 ALRACVLVFSLALHSVFEGLAVG--LQRDRARAMELCLALLLHKGILAVSLSLRLLQSHL 234
A A +++ LH+ +GLA+G + + +A+ H+ + L L
Sbjct: 593 ATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHE----LPHELGDFAVLL 648
Query: 235 RAQVVAGCGILFSCMTPLGIGLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQ 294
+A + +L++ ++ + LG A G + + + AG F+Y+ ++++P+
Sbjct: 649 KAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVPE 708
Query: 295 EL 296
L
Sbjct: 709 ML 710
>gi|42544153 leukocyte receptor tyrosine kinase isoform 1 precursor
[Homo sapiens]
Length = 864
Score = 30.4 bits (67), Expect = 2.2
Identities = 50/191 (26%), Positives = 76/191 (39%), Gaps = 41/191 (21%)
Query: 122 LVLVMEQITLAYKEQSGPSP-LEETRALLGTVNGGP------------QHWHDGPGVPQA 168
L+LV ++ +E PSP LE ++ + P Q W PGV +
Sbjct: 446 LILVKQKKWQGLQEMRLPSPELELSKLRTSAIRTAPNPYYCQVGLGPAQSWPLPPGVTEV 505
Query: 169 SGAPATPSALRACVLVFSLALHSVFEGLAVGLQRDRARAM-------ELC---------- 211
S PA + LRA + A V+EGL +GL D + ELC
Sbjct: 506 S--PANVTLLRA---LGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPELCSPQDELDFLM 560
Query: 212 ----LALLLHKGIL-AVSLSLRLLQSHLRAQVVAGCGILFSCMTPLGIGLGAALAESAGP 266
++ H+ I+ V LSLR + ++++G G + S + LG
Sbjct: 561 EALIISKFRHQNIVRCVGLSLRATPRLILLELMSG-GDMKSFLRHSRPHLGQPSPLVMRD 619
Query: 267 LHQLAQSVLEG 277
L QLAQ + +G
Sbjct: 620 LLQLAQDIAQG 630
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.141 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,510,243
Number of Sequences: 37866
Number of extensions: 590171
Number of successful extensions: 2290
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 2240
Number of HSP's gapped (non-prelim): 64
length of query: 324
length of database: 18,247,518
effective HSP length: 102
effective length of query: 222
effective length of database: 14,385,186
effective search space: 3193511292
effective search space used: 3193511292
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.