Search of human proteins with 211904152

Search of human proteins with 211904152

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|211904152 plasminogen activator inhibitor type 1, member 2
isoform b precursor [Homo sapiens]
         (397 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|211904156 plasminogen activator inhibitor type 1, member 2 is...   788   0.0  
gi|211904154 plasminogen activator inhibitor type 1, member 2 is...   788   0.0  
gi|211904152 plasminogen activator inhibitor type 1, member 2 is...   788   0.0  
gi|24307907 plasminogen activator inhibitor type 1, member 2 iso...   781   0.0  
gi|10835159 plasminogen activator inhibitor-1 [Homo sapiens]          300   2e-81
gi|170295807 neuroserpin precursor [Homo sapiens]                     238   9e-63
gi|4826904 neuroserpin precursor [Homo sapiens]                       238   9e-63
gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member...   214   1e-55
gi|41152086 serine (or cysteine) proteinase inhibitor, clade B (...   191   8e-49
gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (...   189   3e-48
gi|157674356 nexin-related serine protease inhibitor [Homo sapiens]   188   6e-48
gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (...   185   5e-47
gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Hom...   180   2e-45
gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo s...   178   7e-45
gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (o...   178   9e-45
gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s...   174   1e-43
gi|38504669 serine (or cysteine) proteinase inhibitor, clade B (...   174   2e-43
gi|38504673 serine (or cysteine) proteinase inhibitor, clade B (...   174   2e-43
gi|219689110 serine (or cysteine) proteinase inhibitor, clade B ...   168   9e-42
gi|4505595 serine (or cysteine) proteinase inhibitor, clade B (o...   168   9e-42
gi|4826902 serine (or cysteine) proteinase inhibitor, clade B (o...   166   4e-41
gi|17998551 serine (or cysteine) proteinase inhibitor, clade B (...   165   6e-41
gi|110225347 serine (or cysteine) proteinase inhibitor, clade A ...   164   2e-40
gi|8393956 serine (or cysteine) proteinase inhibitor, clade B (o...   155   6e-38
gi|73858564 corticosteroid binding globulin precursor [Homo sapi...   148   1e-35
gi|194018472 serine (or cysteine) proteinase inhibitor, clade A ...   146   3e-35
gi|154759291 serine (or cysteine) proteinase inhibitor, clade A ...   144   2e-34
gi|7705879 serine (or cysteine) proteinase inhibitor, clade A (a...   144   2e-34
gi|73858566 heparin cofactor II precursor [Homo sapiens]              143   3e-34
gi|167860126 serine (or cysteine) proteinase inhibitor, clade B ...   140   3e-33

>gi|211904156 plasminogen activator inhibitor type 1, member 2
           isoform c precursor [Homo sapiens]
          Length = 409

 Score =  788 bits (2034), Expect = 0.0
 Identities = 397/397 (100%), Positives = 397/397 (100%)

Query: 1   MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIAS 60
           MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIAS
Sbjct: 13  MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIAS 72

Query: 61  VLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNAS 120
           VLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNAS
Sbjct: 73  VLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNAS 132

Query: 121 EIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTR 180
           EIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTR
Sbjct: 133 EIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTR 192

Query: 181 LVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYN 240
           LVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYN
Sbjct: 193 LVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYN 252

Query: 241 FIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVA 300
           FIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVA
Sbjct: 253 FIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVA 312

Query: 301 QTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAI 360
           QTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAI
Sbjct: 313 QTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAI 372

Query: 361 LIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 397
           LIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
Sbjct: 373 LIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 409


>gi|211904154 plasminogen activator inhibitor type 1, member 2
           isoform b precursor [Homo sapiens]
          Length = 397

 Score =  788 bits (2034), Expect = 0.0
 Identities = 397/397 (100%), Positives = 397/397 (100%)

Query: 1   MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIAS 60
           MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIAS
Sbjct: 1   MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIAS 60

Query: 61  VLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNAS 120
           VLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNAS
Sbjct: 61  VLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNAS 120

Query: 121 EIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTR 180
           EIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTR
Sbjct: 121 EIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTR 180

Query: 181 LVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYN 240
           LVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYN
Sbjct: 181 LVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYN 240

Query: 241 FIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVA 300
           FIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVA
Sbjct: 241 FIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVA 300

Query: 301 QTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAI 360
           QTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAI
Sbjct: 301 QTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAI 360

Query: 361 LIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 397
           LIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
Sbjct: 361 LIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 397


>gi|211904152 plasminogen activator inhibitor type 1, member 2
           isoform b precursor [Homo sapiens]
          Length = 397

 Score =  788 bits (2034), Expect = 0.0
 Identities = 397/397 (100%), Positives = 397/397 (100%)

Query: 1   MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIAS 60
           MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIAS
Sbjct: 1   MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIAS 60

Query: 61  VLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNAS 120
           VLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNAS
Sbjct: 61  VLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNAS 120

Query: 121 EIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTR 180
           EIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTR
Sbjct: 121 EIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTR 180

Query: 181 LVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYN 240
           LVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYN
Sbjct: 181 LVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYN 240

Query: 241 FIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVA 300
           FIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVA
Sbjct: 241 FIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVA 300

Query: 301 QTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAI 360
           QTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAI
Sbjct: 301 QTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAI 360

Query: 361 LIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 397
           LIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
Sbjct: 361 LIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 397


>gi|24307907 plasminogen activator inhibitor type 1, member 2
           isoform a precursor [Homo sapiens]
          Length = 398

 Score =  781 bits (2016), Expect = 0.0
 Identities = 396/398 (99%), Positives = 396/398 (99%), Gaps = 1/398 (0%)

Query: 1   MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIAS 60
           MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIAS
Sbjct: 1   MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIAS 60

Query: 61  VLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNAS 120
           VLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNAS
Sbjct: 61  VLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNAS 120

Query: 121 EIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTR 180
           EIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTR
Sbjct: 121 EIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTR 180

Query: 181 LVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYN 240
           LVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYN
Sbjct: 181 LVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYN 240

Query: 241 FIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVA 300
           FIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVA
Sbjct: 241 FIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVA 300

Query: 301 QTDLKEPLKVLGITDMFDSSKANFAKITR-SENLHVSHILQKAKIEVSEDGTKASAATTA 359
           QTDLKEPLKVLGITDMFDSSKANFAKIT  SENLHVSHILQKAKIEVSEDGTKASAATTA
Sbjct: 301 QTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTA 360

Query: 360 ILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 397
           ILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
Sbjct: 361 ILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 398


>gi|10835159 plasminogen activator inhibitor-1 [Homo sapiens]
          Length = 402

 Score =  300 bits (767), Expect = 2e-81
 Identities = 157/379 (41%), Positives = 234/379 (61%), Gaps = 3/379 (0%)

Query: 21  HFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMV 80
           H  P  +  L S+ G++VF Q+ ++    N+V SP+G+ASVL MLQL   G T++Q+   
Sbjct: 25  HHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAA 84

Query: 81  MRYGVN--GVGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEV 138
           M + ++  G+   L+ + K ++   NKD ++  +A+FV+   ++   F+     +F+  V
Sbjct: 85  MGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTV 144

Query: 139 RNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQ 198
           + V+F +   A   IN WVK  T+ MI NLL    +D  LTRLVLVNA+YF G WK+ F 
Sbjct: 145 KQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAVDQ-LTRLVLVNALYFNGQWKTPFP 203

Query: 199 PENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALP 258
             +T +R F  +DG +  VPM+AQ + F     + P+  +Y+ +ELPYHG+++SM IA P
Sbjct: 204 DSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAP 263

Query: 259 TESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFD 318
            E   PLSA+   +S + I  W   M      ++LPKF+   + DL++PL+ LG+TDMF 
Sbjct: 264 YEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFR 323

Query: 319 SSKANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPWFIVDRPFLF 378
             +A+F  ++  E LHV+  LQK KIEV+E GT AS++T  I+ AR +P   I+DRPFLF
Sbjct: 324 QFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLF 383

Query: 379 FIRHNPTGAVLFMGQINKP 397
            +RHNPTG VLFMGQ+ +P
Sbjct: 384 VVRHNPTGTVLFMGQVMEP 402


>gi|170295807 neuroserpin precursor [Homo sapiens]
          Length = 410

 Score =  238 bits (606), Expect = 9e-63
 Identities = 130/378 (34%), Positives = 223/378 (58%), Gaps = 11/378 (2%)

Query: 28  EELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNG 87
           EE  ++  + ++N++  +   +NI+ SP  IA  +GM++LGA G T+K++   M Y    
Sbjct: 23  EEAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLK 82

Query: 88  VGK---ILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFE 144
            G+    LK+ +  + +K+++ ++ +AN++FV+N   +   F+   K  F   V +V+F 
Sbjct: 83  NGEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFS 142

Query: 145 DPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKK 204
              +  + IN WV+N T +++ +L+SP   D   T L L+NAVYFKG WKS+F+PENT+ 
Sbjct: 143 QNVAVANYINKWVENNTNNLVKDLVSPRDFDAA-TYLALINAVYFKGNWKSQFRPENTRT 201

Query: 205 RTFVAADGKSYQVPMLAQLSVFRCGSTS-APNDLW--YNFIELPYHGESISMLIALPTES 261
            +F   D    Q+PM+ Q   F  G  S   N+    Y  +E+PY G+ ISM++ L +  
Sbjct: 202 FSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVL-SRQ 260

Query: 262 STPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSK 321
             PL+ + P +  + ++ W + +  ++V+V LP+FT   + DLK+ LK LGIT++F    
Sbjct: 261 EVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIF-IKD 319

Query: 322 ANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSP--PWFIVDRPFLFF 379
           AN   ++ ++ + +S  + K+ +EV+E+G++A+A +  I I+R +   P  IVD PF F 
Sbjct: 320 ANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFL 379

Query: 380 IRHNPTGAVLFMGQINKP 397
           IR+  TG +LFMG++  P
Sbjct: 380 IRNRRTGTILFMGRVMHP 397


>gi|4826904 neuroserpin precursor [Homo sapiens]
          Length = 410

 Score =  238 bits (606), Expect = 9e-63
 Identities = 130/378 (34%), Positives = 223/378 (58%), Gaps = 11/378 (2%)

Query: 28  EELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNG 87
           EE  ++  + ++N++  +   +NI+ SP  IA  +GM++LGA G T+K++   M Y    
Sbjct: 23  EEAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLK 82

Query: 88  VGK---ILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFE 144
            G+    LK+ +  + +K+++ ++ +AN++FV+N   +   F+   K  F   V +V+F 
Sbjct: 83  NGEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFS 142

Query: 145 DPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKK 204
              +  + IN WV+N T +++ +L+SP   D   T L L+NAVYFKG WKS+F+PENT+ 
Sbjct: 143 QNVAVANYINKWVENNTNNLVKDLVSPRDFDAA-TYLALINAVYFKGNWKSQFRPENTRT 201

Query: 205 RTFVAADGKSYQVPMLAQLSVFRCGSTS-APNDLW--YNFIELPYHGESISMLIALPTES 261
            +F   D    Q+PM+ Q   F  G  S   N+    Y  +E+PY G+ ISM++ L +  
Sbjct: 202 FSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVL-SRQ 260

Query: 262 STPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSK 321
             PL+ + P +  + ++ W + +  ++V+V LP+FT   + DLK+ LK LGIT++F    
Sbjct: 261 EVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIF-IKD 319

Query: 322 ANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSP--PWFIVDRPFLFF 379
           AN   ++ ++ + +S  + K+ +EV+E+G++A+A +  I I+R +   P  IVD PF F 
Sbjct: 320 ANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFL 379

Query: 380 IRHNPTGAVLFMGQINKP 397
           IR+  TG +LFMG++  P
Sbjct: 380 IRNRRTGTILFMGRVMHP 397


>gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member 2
           [Homo sapiens]
          Length = 405

 Score =  214 bits (544), Expect = 1e-55
 Identities = 122/354 (34%), Positives = 204/354 (57%), Gaps = 9/354 (2%)

Query: 49  DNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGK---ILKKINKAIVSKKNK 105
           DNI+ SP GI  VL M+QLGA G+ ++Q+   ++      G+   +LK    AI  KK +
Sbjct: 43  DNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGEEFFVLKSFFSAISEKKQE 102

Query: 106 DIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMI 165
               +ANA++++    ++  ++  NK+ FQ  ++ V+F+D  +  + I+ WV+ +T   I
Sbjct: 103 FTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQDAKACAEMISTWVERKTDGKI 162

Query: 166 DNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSV 225
            ++ S +   G LTRLVLVNA+YFKG WK +F+ E+T+   F   +G + ++PM+  L  
Sbjct: 163 KDMFSGEEF-GPLTRLVLVNAIYFKGDWKQKFRKEDTQLINFTKKNGSTVKIPMMKALLR 221

Query: 226 FRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMV 285
            + G  S  + L Y  +EL Y G+  S++I LP E    +  +   I+ + I  W+S M 
Sbjct: 222 TKYGYFS-ESSLNYQVLELSYKGDEFSLIIILPAE-GMDIEEVEKLITAQQILKWLSEMQ 279

Query: 286 PKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIE 345
            + V++ LP+F    + D K+ L  L IT++F S   + + IT S  ++VS + QK   E
Sbjct: 280 EEEVEISLPRFKVEQKVDFKDVLYSLNITEIF-SGGCDLSGITDSSEVYVSQVTQKVFFE 338

Query: 346 VSEDGTKASAATTAIL--IARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 397
           ++EDG++A+ +T   +  I   +   FI + PFLF ++HNPT ++LFMG++  P
Sbjct: 339 INEDGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMKHNPTESILFMGRVTNP 392


>gi|41152086 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 6 [Homo sapiens]
          Length = 376

 Score =  191 bits (486), Expect = 8e-49
 Identities = 115/357 (32%), Positives = 204/357 (57%), Gaps = 15/357 (4%)

Query: 50  NIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKD--- 106
           N+  SP  ++  L M+ +GA G T  Q+A ++ +  +G G  + +  ++++++ NK    
Sbjct: 26  NVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSGGGGDIHQGFQSLLTEVNKTGTQ 85

Query: 107 -IVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDS-INAWVKNETRDM 164
            ++ +AN +F + + +    F    +  +Q E+  ++F          IN WV  +T   
Sbjct: 86  YLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEKSRKHINTWVAEKTEGK 145

Query: 165 IDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLS 224
           I  LLSP  +D  LTRLVLVNAVYF+G W  +F  ENT++R F  +  +   V M+ + S
Sbjct: 146 IAELLSPGSVDP-LTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFKQS 204

Query: 225 VFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSW--MS 282
            F+    +   +++   + LPY G+ ++M+I LP E +T L  +   ++ +    W  + 
Sbjct: 205 TFK---KTYIGEIFTQILVLPYVGKELNMIIMLPDE-TTDLRTVEKELTYEKFVEWTRLD 260

Query: 283 IMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKA 342
           +M  + V+V LP+F      D++  L+ LG+TD F+  KA+F+ +++++ L +S ++ K+
Sbjct: 261 MMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGMSQTD-LSLSKVVHKS 319

Query: 343 KIEVSEDGTKASAATTAILIARSS--PPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 397
            +EV+E+GT+A+AAT AI++ R +   P F  D PFLFFI+H+ T  +LF G+ + P
Sbjct: 320 FVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFIQHSKTNGILFCGRFSSP 376


>gi|13489087 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 1 [Homo sapiens]
          Length = 379

 Score =  189 bits (481), Expect = 3e-48
 Identities = 128/386 (33%), Positives = 201/386 (52%), Gaps = 22/386 (5%)

Query: 27  LEELGS-NT--GIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRY 83
           +E+L S NT   + +F  + ++ P  NI ISP  I+S + M+ LG  G T  QL+    +
Sbjct: 1   MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60

Query: 84  G-VNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVN 142
             V  V    + +N  I  +    I+ +AN ++ +        F+   +  +  ++ +V+
Sbjct: 61  NTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD 120

Query: 143 FEDPAS-ACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPEN 201
           F+  +  A  +IN WVK +T   I  LL+  ++D  +T+LVLVNA+YFKG WK +F  E 
Sbjct: 121 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDN-MTKLVLVNAIYFKGNWKDKFMKEA 179

Query: 202 TKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTE- 260
           T    F         V M+ Q   F  G      DL    +ELPY GE +SM+I LP + 
Sbjct: 180 TTNAPFRLNKKDRKTVKMMYQKKKFAYGYIE---DLKCRVLELPYQGEELSMVILLPDDI 236

Query: 261 --SSTPLSAIIPHISTKTIDSWMSIMVPKR-----VQVILPKFTAVAQTDLKEPLKVLGI 313
              ST L  I   ++ + +  W     P+      V V LP+F       L   L  LG+
Sbjct: 237 EDESTGLKKIEEQLTLEKLHEWTK---PENLDFIEVNVSLPRFKLEESYTLNSDLARLGV 293

Query: 314 TDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPW--FI 371
            D+F+SSKA+ + ++ + ++ +S I+ K+ +EV+E+GT+A+AAT  I       P   F 
Sbjct: 294 QDLFNSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFT 353

Query: 372 VDRPFLFFIRHNPTGAVLFMGQINKP 397
            D PFLFFIRHN +G++LF+G+ + P
Sbjct: 354 ADHPFLFFIRHNSSGSILFLGRFSSP 379


>gi|157674356 nexin-related serine protease inhibitor [Homo sapiens]
          Length = 424

 Score =  188 bits (478), Expect = 6e-48
 Identities = 125/400 (31%), Positives = 192/400 (48%), Gaps = 11/400 (2%)

Query: 5   LPLFLLASVTLPSICSHFNPLSLEE---LGSNTGIQVFNQIVKSRPHDNIVISPHGIASV 61
           +P FL+      S C   N    E    L +   + ++  +   R   N VISP G++  
Sbjct: 1   MPPFLITLFLFHSCCLRANGHLREGMTLLKTEFALHLYQSVAACRNETNFVISPAGVSLP 60

Query: 62  LGMLQLGADGRTKKQLAMVMRYGVNG--VGKILKKINKAIVSKKNKDIVTVANAVFVKNA 119
           L +LQ GA+G T +QLA  + Y V+   V   L  +   + +      + +A ++FV+  
Sbjct: 61  LEILQFGAEGSTGQQLADALGYTVHDKRVKDFLHAVYATLPTSSQGTEMELACSLFVQVG 120

Query: 120 SEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSP-----DLI 174
           + +   FV          +   +  +P S     +     ET     +   P     + +
Sbjct: 121 TPLSPCFVEHVSWWANSSLEPADLSEPNSTAIQTSEGASRETAGGGPSE-GPGGWPWEQV 179

Query: 175 DGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAP 234
                +LVLV+ + F+G W+ RF   +T+   F  A G   QVPM+ Q +    G     
Sbjct: 180 SAAFAQLVLVSTMSFQGTWRKRFSSTDTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDT 239

Query: 235 NDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILP 294
                  +ELPY G ++S+ + LP +  TPLS I PH++  TI  W + +   R+ V LP
Sbjct: 240 AGHQVGVLELPYLGSAVSLFLVLPRDKDTPLSHIEPHLTASTIHLWTTSLRRARMDVFLP 299

Query: 295 KFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKAS 354
           +F    Q +LK  L   G+TD+FD  KAN   I+  +  +VS  + KAKIEV E+GTKAS
Sbjct: 300 RFRIQNQFNLKSILNSWGVTDLFDPLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKAS 359

Query: 355 AATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQI 394
            AT  +L+ RS  P F  DRPF++F+R   TG  +F  +I
Sbjct: 360 GATALLLLKRSRIPIFKADRPFIYFLREPNTGITVFFDRI 399


>gi|28076869 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 4 [Homo sapiens]
          Length = 390

 Score =  185 bits (470), Expect = 5e-47
 Identities = 127/395 (32%), Positives = 207/395 (52%), Gaps = 30/395 (7%)

Query: 26  SLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMR--- 82
           SL E  +     +F Q  KS+  +NI  SP  I S LGM+ LGA   T +Q++ V+    
Sbjct: 3   SLSEANTKFMFDLFQQFRKSK-ENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQ 61

Query: 83  -----------YGVNGVGKILKKINKAIVS-KKNKDI--VTVANAVFVKNASEIEVPFVT 128
                      Y V+  G +  +  K +    K+ D   + +AN +F +   +    ++ 
Sbjct: 62  VTENTTEKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLD 121

Query: 129 RNKDVFQCEVRNVNFED-PASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAV 187
             K  +Q  V + +F + P  +   IN+WV+++T + I NL  PD   G  T LVLVNA+
Sbjct: 122 AIKKFYQTSVESTDFANAPEESRKKINSWVESQTNEKIKNLF-PDGTIGNDTTLVLVNAI 180

Query: 188 YFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYH 247
           YFKG W+++F+ ENTK+  F         V M+ Q + F   + +   D+    +E+PY 
Sbjct: 181 YFKGQWENKFKKENTKEEKFWPNKNTYKSVQMMRQYNSF---NFALLEDVQAKVLEIPYK 237

Query: 248 GESISMLIALPTESSTPLSAIIPHISTKTIDSWMSI--MVPKRVQVILPKFTAVAQTDLK 305
           G+ +SM++ LP E    L  +   ++ + +  W S+  M    V + LP+F      DLK
Sbjct: 238 GKDLSMIVLLPNEID-GLQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLK 296

Query: 306 EPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAILIARS 365
           + L+ +G+ ++F+   A+ + +T S  L VS +L KA +EV+E+G +A+AAT  +++  S
Sbjct: 297 DTLRTMGMVNIFNGD-ADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELS 355

Query: 366 SPPW---FIVDRPFLFFIRHNPTGAVLFMGQINKP 397
           SP     F  + PFLFFIR N T ++LF G+ + P
Sbjct: 356 SPSTNEEFCCNHPFLFFIRQNKTNSILFYGRFSSP 390


>gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Homo
           sapiens]
          Length = 392

 Score =  180 bits (457), Expect = 2e-45
 Identities = 116/385 (30%), Positives = 195/385 (50%), Gaps = 28/385 (7%)

Query: 36  IQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYG----------- 84
           + VF ++  +   DNI  S   +   L M+ LGA G T++QL  V+ +            
Sbjct: 13  LDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVDSLKPGFK 72

Query: 85  ----VNGVGKILKKINKAIVSKKNKD---IVTVANAVFVKNASEIEVPFVTRNKDVFQCE 137
                +  G+I  +           D    +++AN ++          +++ ++  +Q  
Sbjct: 73  DSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQYLSCSEKWYQAR 132

Query: 138 VRNVNFEDPASAC-DSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSR 196
           ++ V+FE        +INAWV+N+T   + NL     ID     +VLVNA+YFKG W+++
Sbjct: 133 LQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSV-MVLVNAIYFKGQWQNK 191

Query: 197 FQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIA 256
           FQ   T K  F  ++GK+  V M+ Q+  F+      P       +ELPY    +SM+I 
Sbjct: 192 FQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQ---MQVLELPYVNNKLSMIIL 248

Query: 257 LPTESSTPLSAIIPHISTKTIDSWMSI--MVPKRVQVILPKFTAVAQTDLKEPLKVLGIT 314
           LP   +  L  I   +++ T   W S   M+ + V+V LP+F    + +L   LK LG+T
Sbjct: 249 LPVGIAN-LKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKSLGVT 307

Query: 315 DMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSP--PWFIV 372
           D+F+  KA+ + ++ ++ L++S  + K+ ++VSE+GT+A+AAT   +  +S P    F  
Sbjct: 308 DLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMRAQFKA 367

Query: 373 DRPFLFFIRHNPTGAVLFMGQINKP 397
           + PFLFFIRH  T  +LF G++  P
Sbjct: 368 NHPFLFFIRHTHTNTILFCGKLASP 392


>gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo
           sapiens]
          Length = 464

 Score =  178 bits (452), Expect = 7e-45
 Identities = 114/363 (31%), Positives = 193/363 (53%), Gaps = 19/363 (5%)

Query: 48  HDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGV------NGVGKILKKINKAIVS 101
           +DNI +SP  I++   M +LGA   T +QL  V ++        + +     K+N  +  
Sbjct: 105 NDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYR 164

Query: 102 KKNKDIVTV-ANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDS-INAWVKN 159
           K NK    V AN +F   +      +   ++ V+  +++ ++F++ A    + IN WV N
Sbjct: 165 KANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRAAINKWVSN 224

Query: 160 ETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPM 219
           +T   I +++  + I+  LT LVLVN +YFKGLWKS+F PENT+K  F  ADG+S    M
Sbjct: 225 KTEGRITDVIPSEAINE-LTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSASM 283

Query: 220 LAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDS 279
           + Q   FR    +    +    +ELP+ G+ I+M++ LP    + L+ +   ++ + +  
Sbjct: 284 MYQEGKFRYRRVAEGTQV----LELPFKGDDITMVLILPKPEKS-LAKVEKELTPEVLQE 338

Query: 280 WMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRS--ENLHVSH 337
           W+  +    + V +P+F       LKE L+ +G+ D+F   K+    I     ++L+VS 
Sbjct: 339 WLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSD 398

Query: 338 ILQKAKIEVSEDGTKASAATTAILIARSSPP---WFIVDRPFLFFIRHNPTGAVLFMGQI 394
              KA +EV+E+G++A+A+T  ++  RS  P    F  +RPFL FIR  P   ++FMG++
Sbjct: 399 AFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRV 458

Query: 395 NKP 397
             P
Sbjct: 459 ANP 461


>gi|5902072 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 3 [Homo sapiens]
          Length = 390

 Score =  178 bits (451), Expect = 9e-45
 Identities = 128/396 (32%), Positives = 205/396 (51%), Gaps = 32/396 (8%)

Query: 26  SLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMR--- 82
           SL E  +     +F Q  KS+  +NI  SP  I S LGM+ LGA   T +Q+  V+    
Sbjct: 3   SLSEANTKFMFDLFQQFRKSK-ENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQ 61

Query: 83  -----------YGVNGVGKILKKINKAIVS-KKNKDI--VTVANAVFVKNASEIEVPFVT 128
                      Y V+  G +  +  K +    K+ D   + +AN +F +        ++ 
Sbjct: 62  VTENTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLD 121

Query: 129 RNKDVFQCEVRNVNFED-PASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAV 187
             K  +Q  V +V+F + P  +   IN+WV+++T + I NL+ P+   G  T LVLVNA+
Sbjct: 122 AIKKFYQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLI-PEGNIGSNTTLVLVNAI 180

Query: 188 YFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYH 247
           YFKG W+ +F  E+TK+  F         + M+ Q + F   S     D+    +E+PY 
Sbjct: 181 YFKGQWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASL---EDVQAKVLEIPYK 237

Query: 248 GESISMLIALPTESSTPLSAIIPHISTKTIDSWMSI--MVPKRVQVILPKFTAVAQTDLK 305
           G+ +SM++ LP E    L  +   ++ + +  W S+  M   RV + LP+F      DLK
Sbjct: 238 GKDLSMIVLLPNEID-GLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLK 296

Query: 306 EPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAILIARS 365
           + L+ +G+ D+F+   A+ + +T S  L +S +L KA +EV+E+G +A+AA TA++   S
Sbjct: 297 DTLRTMGMVDIFNGD-ADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAA-TAVVGFGS 354

Query: 366 SP----PWFIVDRPFLFFIRHNPTGAVLFMGQINKP 397
           SP      F  + PFLFFIR N T ++LF G+ + P
Sbjct: 355 SPTSTNEEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390


>gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo
           sapiens]
          Length = 376

 Score =  174 bits (442), Expect = 1e-43
 Identities = 116/385 (30%), Positives = 192/385 (49%), Gaps = 23/385 (5%)

Query: 27  LEELGSNTG---IQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRY 83
           +E L + +G   I++   + +  P  N+  SP  I+S L M+ LGA G T  Q+A  +  
Sbjct: 1   METLSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSL 60

Query: 84  GV-----NGVGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEV 138
                       +L ++NKA      + ++  AN +F +   +    F       +  E+
Sbjct: 61  NTEEDIHRAFQSLLTEVNKA----GTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAEL 116

Query: 139 RNVNFEDPA-SACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRF 197
           + ++F   A  +   IN WV  +T   I+ LL    ID   TRLVLVNA+YFKG W   F
Sbjct: 117 KELSFIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAE-TRLVLVNAIYFKGKWNEPF 175

Query: 198 QPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIAL 257
               T++  F     +   V M+ Q + F+        ++    +ELPY  + +S+L+ L
Sbjct: 176 DETYTREMPFKINQEEQRPVQMMYQEATFKLAHV---GEVRAQLLELPYARKELSLLVLL 232

Query: 258 PTESSTPLSAIIPHISTKTIDSWM--SIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITD 315
           P +    LS +   ++ + + +W     M    V+V+LPKF      D++  L+ LGI D
Sbjct: 233 P-DDGVELSTVEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVD 291

Query: 316 MFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAILIAR---SSPPWFIV 372
            F   KA+ + ++   +L +S  + K+ +EV+E+GT+A+AA++  ++A     S P F  
Sbjct: 292 AFQQGKADLSAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFCA 351

Query: 373 DRPFLFFIRHNPTGAVLFMGQINKP 397
           D PFLFFIRHN   ++LF G+ + P
Sbjct: 352 DHPFLFFIRHNRANSILFCGRFSSP 376


>gi|38504669 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 8 isoform a [Homo sapiens]
          Length = 374

 Score =  174 bits (440), Expect = 2e-43
 Identities = 112/375 (29%), Positives = 193/375 (51%), Gaps = 12/375 (3%)

Query: 29  ELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVM-RYGVNG 87
           E      I +F  + +     N+  SP  I+S L M+ +GA G T  Q++  +  Y    
Sbjct: 6   EANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKDGD 65

Query: 88  VGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPA 147
           + +  + +   +     + ++  AN +F +   +    F    +  +Q E+  ++F +  
Sbjct: 66  IHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDT 125

Query: 148 SACDS-INAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRT 206
             C   IN WV  +T   I  +L    +D  LT+LVLVNA+YFKG W  +F  + T+   
Sbjct: 126 EECRKHINDWVAEKTEGKISEVLDAGTVDP-LTKLVLVNAIYFKGKWNEQFDRKYTRGML 184

Query: 207 FVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLS 266
           F   + K   V M+ + + F+ G     +++    +ELPY  E +SM+I LP + +T L+
Sbjct: 185 FKTNEEKK-TVQMMFKEAKFKMGYA---DEVHTQVLELPYVEEELSMVILLP-DDNTDLA 239

Query: 267 AIIPHISTKTIDSWMSI--MVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANF 324
            +   ++ +   +W +   +   +VQV LP+       DL+  L+ LG+ D FD +KA+F
Sbjct: 240 VVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADF 299

Query: 325 AKITRSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSS--PPWFIVDRPFLFFIRH 382
           + ++  +N+ +S +  K  +EV+E+GT+A+AAT  +  +R S   P F  D PFLFFIRH
Sbjct: 300 SGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRH 359

Query: 383 NPTGAVLFMGQINKP 397
           + T  +LF G+ + P
Sbjct: 360 HKTNCILFCGRFSSP 374


>gi|38504673 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 8 isoform a [Homo sapiens]
          Length = 374

 Score =  174 bits (440), Expect = 2e-43
 Identities = 112/375 (29%), Positives = 193/375 (51%), Gaps = 12/375 (3%)

Query: 29  ELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVM-RYGVNG 87
           E      I +F  + +     N+  SP  I+S L M+ +GA G T  Q++  +  Y    
Sbjct: 6   EANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKDGD 65

Query: 88  VGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPA 147
           + +  + +   +     + ++  AN +F +   +    F    +  +Q E+  ++F +  
Sbjct: 66  IHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDT 125

Query: 148 SACDS-INAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRT 206
             C   IN WV  +T   I  +L    +D  LT+LVLVNA+YFKG W  +F  + T+   
Sbjct: 126 EECRKHINDWVAEKTEGKISEVLDAGTVDP-LTKLVLVNAIYFKGKWNEQFDRKYTRGML 184

Query: 207 FVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLS 266
           F   + K   V M+ + + F+ G     +++    +ELPY  E +SM+I LP + +T L+
Sbjct: 185 FKTNEEKK-TVQMMFKEAKFKMGYA---DEVHTQVLELPYVEEELSMVILLP-DDNTDLA 239

Query: 267 AIIPHISTKTIDSWMSI--MVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANF 324
            +   ++ +   +W +   +   +VQV LP+       DL+  L+ LG+ D FD +KA+F
Sbjct: 240 VVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADF 299

Query: 325 AKITRSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSS--PPWFIVDRPFLFFIRH 382
           + ++  +N+ +S +  K  +EV+E+GT+A+AAT  +  +R S   P F  D PFLFFIRH
Sbjct: 300 SGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRH 359

Query: 383 NPTGAVLFMGQINKP 397
           + T  +LF G+ + P
Sbjct: 360 HKTNCILFCGRFSSP 374


>gi|219689110 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 2 [Homo sapiens]
          Length = 415

 Score =  168 bits (425), Expect = 9e-42
 Identities = 112/408 (27%), Positives = 194/408 (47%), Gaps = 51/408 (12%)

Query: 36  IQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKI---- 91
           + +F  + K+ P  N+ +SP  I+S + M+ +G+ G T+ Q+A V+++   G   +    
Sbjct: 13  LNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTPMT 72

Query: 92  ----------------------------------LKKINKAIVSKKNKDIVTVANAVFVK 117
                                              + ++ AI +     ++   N +F +
Sbjct: 73  PENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLFGE 132

Query: 118 NASEIEVPFVTRNKDVFQCEVRNVNFEDPAS-ACDSINAWVKNETRDMIDNLLSPDLIDG 176
            ++     ++   +  +  E + V+F + A  A   IN+WVK +T+  I NLL    +DG
Sbjct: 133 KSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSVDG 192

Query: 177 VLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPND 236
             TR+VLVNAVYFKG WK+ F+ +      F     +   V M+        G      D
Sbjct: 193 D-TRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIE---D 248

Query: 237 LWYNFIELPYHGESISMLIALPTES---STPLSAIIPHISTKTIDSWMSI--MVPKRVQV 291
           L    +ELPY G+ +SM + LP E    ST L  +   I+   ++ W S   M    V+V
Sbjct: 249 LKAQILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVEV 307

Query: 292 ILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGT 351
            +P+F      +L+  L+ +G+ D F+  +ANF+ ++   +L +S +  +A ++V+E+GT
Sbjct: 308 YIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNEEGT 367

Query: 352 KASAATTAILIARS--SPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 397
           +A+A T  ++  R+    P F+ D PFLF I H  T  +LF G+ + P
Sbjct: 368 EAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415


>gi|4505595 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 2 [Homo sapiens]
          Length = 415

 Score =  168 bits (425), Expect = 9e-42
 Identities = 112/408 (27%), Positives = 194/408 (47%), Gaps = 51/408 (12%)

Query: 36  IQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKI---- 91
           + +F  + K+ P  N+ +SP  I+S + M+ +G+ G T+ Q+A V+++   G   +    
Sbjct: 13  LNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTPMT 72

Query: 92  ----------------------------------LKKINKAIVSKKNKDIVTVANAVFVK 117
                                              + ++ AI +     ++   N +F +
Sbjct: 73  PENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLFGE 132

Query: 118 NASEIEVPFVTRNKDVFQCEVRNVNFEDPAS-ACDSINAWVKNETRDMIDNLLSPDLIDG 176
            ++     ++   +  +  E + V+F + A  A   IN+WVK +T+  I NLL    +DG
Sbjct: 133 KSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSVDG 192

Query: 177 VLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPND 236
             TR+VLVNAVYFKG WK+ F+ +      F     +   V M+        G      D
Sbjct: 193 D-TRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIE---D 248

Query: 237 LWYNFIELPYHGESISMLIALPTES---STPLSAIIPHISTKTIDSWMSI--MVPKRVQV 291
           L    +ELPY G+ +SM + LP E    ST L  +   I+   ++ W S   M    V+V
Sbjct: 249 LKAQILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVEV 307

Query: 292 ILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGT 351
            +P+F      +L+  L+ +G+ D F+  +ANF+ ++   +L +S +  +A ++V+E+GT
Sbjct: 308 YIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNEEGT 367

Query: 352 KASAATTAILIARS--SPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 397
           +A+A T  ++  R+    P F+ D PFLF I H  T  +LF G+ + P
Sbjct: 368 EAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415


>gi|4826902 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 10 [Homo sapiens]
          Length = 397

 Score =  166 bits (419), Expect = 4e-41
 Identities = 120/393 (30%), Positives = 197/393 (50%), Gaps = 39/393 (9%)

Query: 36  IQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRY----GVNGVGKI 91
           +++  ++ +S    NI  S   I++ L ++ LGA G T  Q+A V+++    GV    + 
Sbjct: 13  LELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQFNRDQGVKCDPES 72

Query: 92  LKKINKAI------------------VSKKNKD-IVTVANAVFVKNASEIEVPFVTRNKD 132
            KK                       + K N D ++  ANA++ +        ++   K 
Sbjct: 73  EKKRKMEFNLSNSEEIHSDFQTLISEILKPNDDYLLKTANAIYGEKTYAFHNKYLEDMKT 132

Query: 133 VFQCEVRNVNFEDPASAC-DSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKG 191
            F  E + VNF + +      IN+WV+ +T   I NLL  D +D   TR++LVNA+YFKG
Sbjct: 133 YFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDST-TRMILVNALYFKG 191

Query: 192 LWKSRFQPENTKKRTFVAADGKSYQVPML---AQLSVFRCGSTSAPNDLWYNFIELPYHG 248
           +W+ +F  +NT ++ F   +  S  V M+    +L +F      A        ++L Y  
Sbjct: 192 IWEHQFLVQNTTEKPFRINETTSKPVQMMFMKKKLHIFHIEKPKAVG------LQLYYKS 245

Query: 249 ESISMLIALPTESSTPLSAIIPHISTKTIDSWMS--IMVPKRVQVILPKFTAVAQTDLKE 306
             +S+LI LP E    L  +   I+ + ++ W S  +M    VQ+ LPKF      DLK 
Sbjct: 246 RDLSLLILLP-EDINGLEQLEKAITYEKLNEWTSADMMELYEVQLHLPKFKLEDSYDLKS 304

Query: 307 PLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSS 366
            L  +G++D F  SKA+F+ ++ + NL +S++  KA +E++E GT+A+A + + +  R  
Sbjct: 305 TLSSMGMSDAFSQSKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAGSGSEIDIRIR 364

Query: 367 PP--WFIVDRPFLFFIRHNPTGAVLFMGQINKP 397
            P   F  + PFLFFIRHN T  +LF G++  P
Sbjct: 365 VPSIEFNANHPFLFFIRHNKTNTILFYGRLCSP 397


>gi|17998551 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 12 [Homo sapiens]
          Length = 405

 Score =  165 bits (418), Expect = 6e-41
 Identities = 119/399 (29%), Positives = 199/399 (49%), Gaps = 47/399 (11%)

Query: 38  VFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGV------------ 85
           +F +I K   H NI  SP  +++ LGM++LGA   +  Q+  V+ +              
Sbjct: 15  LFQEIGKDDRHKNIFFSPLSLSAALGMVRLGARSDSAHQIDEVLHFNEFSQNESKEPDPC 74

Query: 86  --------------NGV-----GKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPF 126
                         +G+     G++L K+++     K    +++AN ++ +    I   +
Sbjct: 75  LKSNKQKAGSLNNESGLVSCYFGQLLSKLDRI----KTDYTLSIANRLYGEQEFPICQEY 130

Query: 127 VTRNKDVFQCEVRNVNFE-DPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVN 185
           +      +   + +V+F+ +P  +   IN WV+ +++  I  L S D I+   T LVLVN
Sbjct: 131 LDGVIQFYHTTIESVDFQKNPEKSRQEINFWVECQSQGKIKELFSKDAINAE-TVLVLVN 189

Query: 186 AVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELP 245
           AVYFK  W++ F  ENT    F     ++  V M+ Q  ++R G      ++    +E+ 
Sbjct: 190 AVYFKAKWETYFDHENTVDAPFCLNANENKSVKMMTQKGLYRIGFIE---EVKAQILEMR 246

Query: 246 YHGESISMLIALPTESSTPLSAIIP---HISTKTIDSWMSI--MVPKRVQVILPKFTAVA 300
           Y    +SM + LP+ S   L  +      I+ + + +W S   M  + V +  P+FT   
Sbjct: 247 YTKGKLSMFVLLPSHSKDNLKGLEELERKITYEKMVAWSSSENMSEESVVLSFPRFTLED 306

Query: 301 QTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAI 360
             DL   L+ +GITD+FD ++A+   I+ S NL++S I+ K  +EV E+GT+A+AAT A+
Sbjct: 307 SYDLNSILQDMGITDIFDETRADLTGISPSPNLYLSKIIHKTFVEVDENGTQAAAATGAV 366

Query: 361 LIARSSPPW--FIVDRPFLFFIRHNPTGAVLFMGQINKP 397
           +  RS   W  F  + PFLFFIRHN T  +LF G++  P
Sbjct: 367 VSERSLRSWVEFNANHPFLFFIRHNKTQTILFYGRVCSP 405


>gi|110225347 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 9 isoform
           A [Homo sapiens]
          Length = 435

 Score =  164 bits (414), Expect = 2e-40
 Identities = 107/380 (28%), Positives = 204/380 (53%), Gaps = 24/380 (6%)

Query: 30  LGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGV---- 85
           L ++   +++ ++V   P  NI  SP  +++ L ML LGA   TK Q+   + + +    
Sbjct: 65  LNTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTP 124

Query: 86  -NGVGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFE 144
            + + +  + +  ++        + + +A+FVK   +++  F+   K +++ EV + +F 
Sbjct: 125 ESAIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFS 184

Query: 145 DPASACDSINAWVKNETRDMIDNLLSPDLIDGV--LTRLVLVNAVYFKGLWKSRFQPENT 202
           +P+ A   IN+ VK +T+  +      D+I G+  LT +VLVN ++FK  W+  F PE T
Sbjct: 185 NPSIAQARINSHVKKKTQGKV-----VDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYT 239

Query: 203 KKR-TFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTES 261
           +K   F+  +  +  VPM+ Q   F  G  +  N      +++ Y G++++  + LP++ 
Sbjct: 240 RKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCF---VLQMDYKGDAVAFFV-LPSKG 295

Query: 262 STPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSK 321
              +  +   +S +T+  W   +  + ++V +P+F+  A  +L+  L  +GI ++FD + 
Sbjct: 296 K--MRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKN- 352

Query: 322 ANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAILIARS--SPPWFIV--DRPFL 377
           A+F+ I + ++L VS    KA ++VSE+GT+A+AATT   I RS   P +F V  +R FL
Sbjct: 353 ADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFL 412

Query: 378 FFIRHNPTGAVLFMGQINKP 397
             I +  T  +LF+G++  P
Sbjct: 413 MMITNKATDGILFLGKVENP 432


>gi|8393956 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 13 [Homo sapiens]
          Length = 391

 Score =  155 bits (392), Expect = 6e-38
 Identities = 117/395 (29%), Positives = 184/395 (46%), Gaps = 29/395 (7%)

Query: 26  SLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGV 85
           SL  + +  G  +F ++ K+    NI  SP GI + +GM+ LG  G T  QL  V     
Sbjct: 3   SLGAVSTRLGFDLFKELKKTND-GNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEK 61

Query: 86  NGVGKILKKINKAIV-----------------SKKNKDI-VTVANAVFVKNASEIEVPFV 127
                 +K   K ++                 SK   D  + + N +F +        ++
Sbjct: 62  ETKSSRIKAEEKEVIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYL 121

Query: 128 TRNKDVFQCEVRNVNFEDPASAC-DSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNA 186
              +  +   +  V+F + A      IN+WV+++T + I +L  PD      T+LVLVN 
Sbjct: 122 DYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLF-PDGSISSSTKLVLVNM 180

Query: 187 VYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPY 246
           VYFKG W   F+ ENTK+  F      S  V M+ Q   F   S +   DL    + +PY
Sbjct: 181 VYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSF---SFTFLEDLQAKILGIPY 237

Query: 247 HGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSI--MVPKRVQVILPKFTAVAQTDL 304
               +SM + LP +    L  II  IS + +  W S   M  ++V + LP+F      DL
Sbjct: 238 KNNDLSMFVLLPNDIDG-LEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDL 296

Query: 305 KEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAILIAR 364
           +  L  +G+ D F   KA+++ ++    L+    L  + + V+E+GT+A+AAT       
Sbjct: 297 EAVLAAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVT 356

Query: 365 SSPPWFIV--DRPFLFFIRHNPTGAVLFMGQINKP 397
           S+P    V  + PFLFFIRHN + ++LF G+ + P
Sbjct: 357 SAPGHENVHCNHPFLFFIRHNESNSILFFGRFSSP 391


>gi|73858564 corticosteroid binding globulin precursor [Homo
           sapiens]
          Length = 405

 Score =  148 bits (373), Expect = 1e-35
 Identities = 103/369 (27%), Positives = 184/369 (49%), Gaps = 23/369 (6%)

Query: 38  VFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNG-----VGKIL 92
           ++  +V   P  NI ISP  I+  L ML LG  G T+ QL   + + +       + +  
Sbjct: 50  LYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETEIHQGF 109

Query: 93  KKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDS 152
           + +++          +T+ NA+F+  + E+   F    K  ++ EV  +NF+D A+A   
Sbjct: 110 QHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAMNFQDWATASRQ 169

Query: 153 INAWVKNETR----DMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFV 208
           IN++VKN+T+    D+   L SP +       LVLVN ++FKG W   F   +T++  F 
Sbjct: 170 INSYVKNKTQGKIVDLFSGLDSPAI-------LVLVNYIFFKGTWTQPFDLASTREENFY 222

Query: 209 AADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAI 268
             +    +VPM+ Q S     S     +L    +++ Y G      I LP +    ++ +
Sbjct: 223 VDETTVVKVPMMLQSSTI---SYLHDAELPCQLVQMNYVGNGTVFFI-LPDKGK--MNTV 276

Query: 269 IPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKIT 328
           I  +S  TI+ W + +   +V + +PK T     DL + L+ +GI D+F +++ANF++IT
Sbjct: 277 IAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLF-TNQANFSRIT 335

Query: 329 RSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAV 388
           +   L  S ++ KA ++++E+G   + +T   L   S P     ++PF+  I  + T + 
Sbjct: 336 QDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRFNQPFIIMIFDHFTWSS 395

Query: 389 LFMGQINKP 397
           LF+ ++  P
Sbjct: 396 LFLARVMNP 404


>gi|194018472 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 5 [Homo
           sapiens]
          Length = 406

 Score =  146 bits (369), Expect = 3e-35
 Identities = 101/372 (27%), Positives = 192/372 (51%), Gaps = 29/372 (7%)

Query: 38  VFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVN---------GV 88
           ++  +  + P  +I  SP  I+  L ML LGA   TK Q+   +   +          G 
Sbjct: 52  LYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGF 111

Query: 89  GKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPAS 148
            ++L+++N+     ++   +++ NA+F     +++  FV+  K ++  +    NF D A 
Sbjct: 112 QQLLQELNQP----RDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAG 167

Query: 149 ACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFV 208
           A   IN +V  +T+  I +LL     + V+   ++VN ++FK  W++ F  + T+++ F 
Sbjct: 168 AMKQINDYVAKQTKGKIVDLLKNLDSNAVV---IMVNYIFFKAKWETSFNHKGTQEQDFY 224

Query: 209 AADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAI 268
                  +VPM+++   +         +L    + +PY G + ++ I LP+E    +  +
Sbjct: 225 VTSETVVRVPMMSREDQYHY---LLDRNLSCRVVGVPYQGNATALFI-LPSEGK--MQQV 278

Query: 269 IPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKIT 328
              +S KT+  W+ +   +++++ LPKF+      L++ L  LGI+++F +S A+ + I+
Sbjct: 279 ENGLSEKTLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVF-TSHADLSGIS 337

Query: 329 RSENLHVSHILQKAKIEVSEDGTKASAATTAILI---ARSSPPWFIVDRPFLFFIRHNPT 385
              N+ VS ++ KA +EV E GT+A+AAT  I     AR +    + +RPFL FI  N  
Sbjct: 338 NHSNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDN-- 395

Query: 386 GAVLFMGQINKP 397
             +LF+G++N+P
Sbjct: 396 -NILFLGKVNRP 406


>gi|154759291 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 10 [Homo
           sapiens]
          Length = 444

 Score =  144 bits (362), Expect = 2e-34
 Identities = 110/375 (29%), Positives = 193/375 (51%), Gaps = 22/375 (5%)

Query: 32  SNTGIQVFNQIVKSRPHD-NIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGK 90
           SN G  +  +I  S  HD N+V SP G++  +  L LGA G T+ Q+   +        K
Sbjct: 80  SNFGFSLLRKI--SMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTK 137

Query: 91  --ILKKINKAIVSKKNKDI---VTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFED 145
             +L  + K +    ++++   +T  +  F+    +++  F   +K  F  E   +NF +
Sbjct: 138 PGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRN 197

Query: 146 PASACDSINAWVKNETRDMIDNLLSPDLIDGVL--TRLVLVNAVYFKGLWKSRFQPENTK 203
            + A   +N ++  ETR  I     P L D +   T+L+LV+ + FKG W + F P  T+
Sbjct: 198 ASQAKRLMNHYINKETRGKI-----PKLFDEINPETKLILVDYILFKGKWLTPFDPVFTE 252

Query: 204 KRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESST 263
             TF     K+ +VPM+     F   +++   +   + ++LPY G + +ML+ L  +   
Sbjct: 253 VDTFHLDKYKTIKVPMMYGAGKF---ASTFDKNFRCHVLKLPYQGNA-TMLVVLMEKMGD 308

Query: 264 PLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKAN 323
            L A+  +++T  +++W+  M  + ++V  PKF    + ++ E L+ +GI  +F S  A+
Sbjct: 309 HL-ALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIF-SPFAD 366

Query: 324 FAKITRS-ENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPWFIVDRPFLFFIRH 382
            ++++ +  NL VS +LQ+  IEV E GT+A A   + + A S PP   VDRPF F I  
Sbjct: 367 LSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYE 426

Query: 383 NPTGAVLFMGQINKP 397
             +G +LF+G++  P
Sbjct: 427 ETSGMLLFLGRVVNP 441


>gi|7705879 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 10 [Homo
           sapiens]
          Length = 444

 Score =  144 bits (362), Expect = 2e-34
 Identities = 110/375 (29%), Positives = 193/375 (51%), Gaps = 22/375 (5%)

Query: 32  SNTGIQVFNQIVKSRPHD-NIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGK 90
           SN G  +  +I  S  HD N+V SP G++  +  L LGA G T+ Q+   +        K
Sbjct: 80  SNFGFSLLRKI--SMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTK 137

Query: 91  --ILKKINKAIVSKKNKDI---VTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFED 145
             +L  + K +    ++++   +T  +  F+    +++  F   +K  F  E   +NF +
Sbjct: 138 PGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRN 197

Query: 146 PASACDSINAWVKNETRDMIDNLLSPDLIDGVL--TRLVLVNAVYFKGLWKSRFQPENTK 203
            + A   +N ++  ETR  I     P L D +   T+L+LV+ + FKG W + F P  T+
Sbjct: 198 ASQAKRLMNHYINKETRGKI-----PKLFDEINPETKLILVDYILFKGKWLTPFDPVFTE 252

Query: 204 KRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESST 263
             TF     K+ +VPM+     F   +++   +   + ++LPY G + +ML+ L  +   
Sbjct: 253 VDTFHLDKYKTIKVPMMYGAGKF---ASTFDKNFRCHVLKLPYQGNA-TMLVVLMEKMGD 308

Query: 264 PLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKAN 323
            L A+  +++T  +++W+  M  + ++V  PKF    + ++ E L+ +GI  +F S  A+
Sbjct: 309 HL-ALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIF-SPFAD 366

Query: 324 FAKITRS-ENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPWFIVDRPFLFFIRH 382
            ++++ +  NL VS +LQ+  IEV E GT+A A   + + A S PP   VDRPF F I  
Sbjct: 367 LSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYE 426

Query: 383 NPTGAVLFMGQINKP 397
             +G +LF+G++  P
Sbjct: 427 ETSGMLLFLGRVVNP 441


>gi|73858566 heparin cofactor II precursor [Homo sapiens]
          Length = 499

 Score =  143 bits (360), Expect = 3e-34
 Identities = 99/359 (27%), Positives = 183/359 (50%), Gaps = 21/359 (5%)

Query: 49  DNIVISPHGIASVLGMLQLGADGRTKKQLAMVM----------RYGVNGVGKILKKINKA 98
           DNI I+P GI++ +GM+ LG  G T +Q+  ++          +Y +  +  + +K+   
Sbjct: 149 DNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVNASSKYEITTIHNLFRKLTHR 208

Query: 99  IVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVK 158
           +  +     +   N ++++    I + F T+ ++ +  E +  +F DPA    + N  +K
Sbjct: 209 LFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQIADFSDPAFISKTNNHIMK 268

Query: 159 NETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVP 218
             T+ +I + L  + ID   T+++++N +YFKG W ++F  E T    F   + +  +V 
Sbjct: 269 L-TKGLIKDAL--ENIDPA-TQMMILNCIYFKGSWVNKFPVEMTHNHNFRLNEREVVKVS 324

Query: 219 MLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTID 278
           M+     F   +     +L  + ++L Y G  ISMLI +P + S  +  +   ++ + ++
Sbjct: 325 MMQTKGNFLAANDQ---ELDCDILQLEYVG-GISMLIVVPHKMSG-MKTLEAQLTPRVVE 379

Query: 279 SWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHI 338
            W   M  +  +V+LPKF      +L E LK++GI  +FD +  N A I+  + + +   
Sbjct: 380 RWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKN-GNMAGIS-DQRIAIDLF 437

Query: 339 LQKAKIEVSEDGTKASAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 397
             +  I V+E+GT+A+  TT   +  S+   F VDRPFLF I  + T  +LFMG++  P
Sbjct: 438 KHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIYEHRTSCLLFMGRVANP 496


>gi|167860126 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 5 [Homo sapiens]
          Length = 375

 Score =  140 bits (352), Expect = 3e-33
 Identities = 92/379 (24%), Positives = 184/379 (48%), Gaps = 13/379 (3%)

Query: 26  SLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRY-G 84
           +L+   S   + +F Q+ +  P  N++ SP  +++ L + Q+GA G T  ++  V+ +  
Sbjct: 3   ALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFEN 62

Query: 85  VNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFE 144
           V  V    + +   +    +   + +   ++V  +  +   F++  K  +  E+  V+F+
Sbjct: 63  VKDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFK 122

Query: 145 DPASACDS-INAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTK 203
           D        IN  +K+ T    +N+L+ + ++   T++++VNA YF G W  +F    TK
Sbjct: 123 DKLEETKGQINNSIKDLTDGHFENILADNSVNDQ-TKILVVNAAYFVGKWMKKFSESETK 181

Query: 204 KRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTE--- 260
           +  F      +  V M+   + F  G+  + N      IELP+  + +SM I LP +   
Sbjct: 182 ECPFRVNKTDTKPVQMMNMEATFCMGNIDSIN---CKIIELPFQNKHLSMFILLPKDVED 238

Query: 261 SSTPLSAIIPHISTKTIDSWM--SIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFD 318
            ST L  I   ++++++  W   S M   +V++ +PKF      D K  L+ LG+  +F 
Sbjct: 239 ESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFS 298

Query: 319 SSKANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPWFIVDRPFLF 378
              ++F+ ++ ++ + +S+++ K  +E++EDG  +     A ++          D PF++
Sbjct: 299 EDTSDFSGMSETKGVALSNVIHKVCLEITEDGGDSIEVPGARILQHKDE--LNADHPFIY 356

Query: 379 FIRHNPTGAVLFMGQINKP 397
            IRHN T  ++F G+   P
Sbjct: 357 IIRHNKTRNIIFFGKFCSP 375


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,442,324
Number of Sequences: 37866
Number of extensions: 518596
Number of successful extensions: 1376
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 1127
Number of HSP's gapped (non-prelim): 90
length of query: 397
length of database: 18,247,518
effective HSP length: 104
effective length of query: 293
effective length of database: 14,309,454
effective search space: 4192670022
effective search space used: 4192670022
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.