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Search of human proteins with 205830407
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|205830407 solute carrier family 39 (zinc transporter),
member 8 isoform c [Homo sapiens]
(393 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|205830407 solute carrier family 39 (zinc transporter), member... 796 0.0
gi|24586665 solute carrier family 39 (zinc transporter), member ... 785 0.0
gi|205830403 solute carrier family 39 (zinc transporter), member... 785 0.0
gi|205830405 solute carrier family 39 (zinc transporter), member... 715 0.0
gi|190358541 solute carrier family 39 (zinc transporter), member... 409 e-114
gi|205830424 solute carrier family 39 (zinc transporter), member... 404 e-113
gi|190360568 solute carrier family 39 (zinc transporter), member... 404 e-113
gi|205830426 solute carrier family 39 (zinc transporter), member... 363 e-100
gi|115430259 solute carrier family 39 (zinc transporter), member... 184 2e-46
gi|115430255 solute carrier family 39 (zinc transporter), member... 184 2e-46
gi|223633939 solute carrier family 39 (zinc transporter), member... 180 2e-45
gi|223633937 solute carrier family 39 (zinc transporter), member... 172 6e-43
gi|153252201 solute carrier family 39 (zinc transporter), member... 155 6e-38
gi|187936949 solute carrier family 39 (zinc transporter), member... 150 2e-36
gi|55741750 solute carrier family 39 (zinc transporter), member ... 150 2e-36
gi|206597541 solute carrier family 39 (metal ion transporter), m... 142 5e-34
gi|206597539 solute carrier family 39 (metal ion transporter), m... 142 5e-34
gi|153252214 solute carrier family 39 (zinc transporter), member... 132 7e-31
gi|117553619 solute carrier family 39, member 7 [Homo sapiens] 85 1e-16
gi|117553608 solute carrier family 39, member 7 [Homo sapiens] 85 1e-16
gi|40255101 solute carrier family 39 (zinc transporter), member ... 74 2e-13
gi|190014617 solute carrier family 39 (zinc transporter), member... 72 1e-12
gi|156415986 solute carrier family 39 (zinc transporter), member... 43 6e-04
gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo... 42 0.001
gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo... 42 0.001
gi|40254928 solute carrier family 39 (zinc transporter), member ... 33 0.34
gi|21361423 solute carrier family 39 (zinc transporter), member ... 33 0.34
gi|122937259 solute carrier family 45, member 4 [Homo sapiens] 30 3.8
gi|27262624 ATP-binding cassette, sub-family A , member 5 [Homo ... 30 4.9
gi|27262626 ATP-binding cassette, sub-family A , member 5 [Homo ... 30 4.9
>gi|205830407 solute carrier family 39 (zinc transporter), member 8
isoform c [Homo sapiens]
Length = 393
Score = 796 bits (2057), Expect = 0.0
Identities = 393/393 (100%), Positives = 393/393 (100%)
Query: 1 MHQHAQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSE 60
MHQHAQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSE
Sbjct: 1 MHQHAQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSE 60
Query: 61 VWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFG 120
VWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFG
Sbjct: 61 VWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFG 120
Query: 121 FDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEKTHQPKA 180
FDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEKTHQPKA
Sbjct: 121 FDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEKTHQPKA 180
Query: 181 LPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEIGTIAWMI 240
LPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEIGTIAWMI
Sbjct: 181 LPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEIGTIAWMI 240
Query: 241 TLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALL 300
TLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALL
Sbjct: 241 TLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALL 300
Query: 301 FNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLREKVTGRK 360
FNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLREKVTGRK
Sbjct: 301 FNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLREKVTGRK 360
Query: 361 TDFTFFMIQNAGMLTGFTAILLITLYAGEIELE 393
TDFTFFMIQNAGMLTGFTAILLITLYAGEIELE
Sbjct: 361 TDFTFFMIQNAGMLTGFTAILLITLYAGEIELE 393
>gi|24586665 solute carrier family 39 (zinc transporter), member 8
isoform a [Homo sapiens]
Length = 460
Score = 785 bits (2027), Expect = 0.0
Identities = 388/388 (100%), Positives = 388/388 (100%)
Query: 6 QCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEVWGYG 65
QCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEVWGYG
Sbjct: 73 QCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEVWGYG 132
Query: 66 FLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPKV 125
FLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPKV
Sbjct: 133 FLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPKV 192
Query: 126 DSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEKTHQPKALPAIN 185
DSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEKTHQPKALPAIN
Sbjct: 193 DSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEKTHQPKALPAIN 252
Query: 186 GVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEIGTIAWMITLCDA 245
GVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEIGTIAWMITLCDA
Sbjct: 253 GVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEIGTIAWMITLCDA 312
Query: 246 LHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLS 305
LHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLS
Sbjct: 313 LHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLS 372
Query: 306 ACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLREKVTGRKTDFTF 365
ACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLREKVTGRKTDFTF
Sbjct: 373 ACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLREKVTGRKTDFTF 432
Query: 366 FMIQNAGMLTGFTAILLITLYAGEIELE 393
FMIQNAGMLTGFTAILLITLYAGEIELE
Sbjct: 433 FMIQNAGMLTGFTAILLITLYAGEIELE 460
>gi|205830403 solute carrier family 39 (zinc transporter), member 8
isoform a [Homo sapiens]
Length = 460
Score = 785 bits (2027), Expect = 0.0
Identities = 388/388 (100%), Positives = 388/388 (100%)
Query: 6 QCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEVWGYG 65
QCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEVWGYG
Sbjct: 73 QCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEVWGYG 132
Query: 66 FLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPKV 125
FLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPKV
Sbjct: 133 FLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPKV 192
Query: 126 DSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEKTHQPKALPAIN 185
DSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEKTHQPKALPAIN
Sbjct: 193 DSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEKTHQPKALPAIN 252
Query: 186 GVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEIGTIAWMITLCDA 245
GVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEIGTIAWMITLCDA
Sbjct: 253 GVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEIGTIAWMITLCDA 312
Query: 246 LHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLS 305
LHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLS
Sbjct: 313 LHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLS 372
Query: 306 ACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLREKVTGRKTDFTF 365
ACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLREKVTGRKTDFTF
Sbjct: 373 ACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLREKVTGRKTDFTF 432
Query: 366 FMIQNAGMLTGFTAILLITLYAGEIELE 393
FMIQNAGMLTGFTAILLITLYAGEIELE
Sbjct: 433 FMIQNAGMLTGFTAILLITLYAGEIELE 460
>gi|205830405 solute carrier family 39 (zinc transporter), member 8
isoform b [Homo sapiens]
Length = 444
Score = 715 bits (1845), Expect = 0.0
Identities = 352/357 (98%), Positives = 353/357 (98%)
Query: 6 QCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEVWGYG 65
QCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEVWGYG
Sbjct: 73 QCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEVWGYG 132
Query: 66 FLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPKV 125
FLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPKV
Sbjct: 133 FLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPKV 192
Query: 126 DSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEKTHQPKALPAIN 185
DSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEKTHQPKALPAIN
Sbjct: 193 DSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEKTHQPKALPAIN 252
Query: 186 GVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEIGTIAWMITLCDA 245
GVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEIGTIAWMITLCDA
Sbjct: 253 GVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEIGTIAWMITLCDA 312
Query: 246 LHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLS 305
LHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLS
Sbjct: 313 LHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLS 372
Query: 306 ACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLREKVTGRKTD 362
ACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLREK+ TD
Sbjct: 373 ACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLREKIIKWATD 429
>gi|190358541 solute carrier family 39 (zinc transporter), member 14
isoform b [Homo sapiens]
Length = 492
Score = 409 bits (1051), Expect = e-114
Identities = 214/404 (52%), Positives = 291/404 (72%), Gaps = 21/404 (5%)
Query: 7 CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPC--------EDRPKHKTRPSH 58
C ++ ++F+ H FS ++I SS+ CP +LQQL+ C E+ + RPS
Sbjct: 91 CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRPSA 150
Query: 59 SEVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEA 118
EVWG+GFLSV++INLASLLG+++ P +K++F ++LT+F+ L+IGTL SNA+FQLIPEA
Sbjct: 151 VEVWGFGFLSVSLINLASLLGVLVLPCTEKAFFSRVLTYFIALSIGTLLSNALFQLIPEA 210
Query: 119 FGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQN--GHTHFGNDNFGPQEKTH 176
FGF+P D YV K+ VFGGFYL FF E++LK+LLK ++ GH+H+ +++ P +K
Sbjct: 211 FGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESL-PSKKDQ 269
Query: 177 QPKALPAI-NGVTCYANP--AVTEANGHIHFDNVSVV----SLQDGKKEPSSCTCLKGPK 229
+ + + NG + P +E +G + V+ S+QD + S+C LKG +
Sbjct: 270 EEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVR 329
Query: 230 LSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILL 289
S+IGT+AWMITL D LHNFIDGLAIGAS T+S+ QG+STS+AILCEEFPHELGDFVILL
Sbjct: 330 YSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILL 389
Query: 290 NAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMN 349
NAGMS +QAL FNFLSAC CY+GLAFGIL G++F+ N IFALAGGMFLYISLADMFPEMN
Sbjct: 390 NAGMSIQQALFFNFLSACCCYLGLAFGILAGSHFSANWIFALAGGMFLYISLADMFPEMN 449
Query: 350 DMLREKVTGRKTDFTF-FMIQNAGMLTGFTAILLITLYAGEIEL 392
++ +E RK F+IQN G+LTGFT ++++T+Y+G+I++
Sbjct: 450 EVCQE--DERKGSILIPFIIQNLGLLTGFTIMVVLTMYSGQIQI 491
>gi|205830424 solute carrier family 39 (zinc transporter), member 14
isoform a [Homo sapiens]
Length = 492
Score = 404 bits (1038), Expect = e-113
Identities = 212/404 (52%), Positives = 287/404 (71%), Gaps = 21/404 (5%)
Query: 7 CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPC--------EDRPKHKTRPSH 58
C ++ ++F+ H FS ++I SS+ CP +LQQL+ C E+ + RPS
Sbjct: 91 CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRPSA 150
Query: 59 SEVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEA 118
EVWGYG L VT+I+L SLLG + P +KK+++ ++L +F+ LAIGTL+SNA+FQLIPEA
Sbjct: 151 VEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEA 210
Query: 119 FGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQN--GHTHFGNDNFGPQEKTH 176
FGF+P D YV K+ VFGGFYL FF E++LK+LLK ++ GH+H+ +++ P +K
Sbjct: 211 FGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESL-PSKKDQ 269
Query: 177 QPKALPAI-NGVTCYANP--AVTEANGHIHFDNVSVV----SLQDGKKEPSSCTCLKGPK 229
+ + + NG + P +E +G + V+ S+QD + S+C LKG +
Sbjct: 270 EEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVR 329
Query: 230 LSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILL 289
S+IGT+AWMITL D LHNFIDGLAIGAS T+S+ QG+STS+AILCEEFPHELGDFVILL
Sbjct: 330 YSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILL 389
Query: 290 NAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMN 349
NAGMS +QAL FNFLSAC CY+GLAFGIL G++F+ N IFALAGGMFLYISLADMFPEMN
Sbjct: 390 NAGMSIQQALFFNFLSACCCYLGLAFGILAGSHFSANWIFALAGGMFLYISLADMFPEMN 449
Query: 350 DMLREKVTGRKTDFTF-FMIQNAGMLTGFTAILLITLYAGEIEL 392
++ +E RK F+IQN G+LTGFT ++++T+Y+G+I++
Sbjct: 450 EVCQE--DERKGSILIPFIIQNLGLLTGFTIMVVLTMYSGQIQI 491
>gi|190360568 solute carrier family 39 (zinc transporter), member 14
isoform a [Homo sapiens]
Length = 492
Score = 404 bits (1038), Expect = e-113
Identities = 212/404 (52%), Positives = 287/404 (71%), Gaps = 21/404 (5%)
Query: 7 CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPC--------EDRPKHKTRPSH 58
C ++ ++F+ H FS ++I SS+ CP +LQQL+ C E+ + RPS
Sbjct: 91 CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRPSA 150
Query: 59 SEVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEA 118
EVWGYG L VT+I+L SLLG + P +KK+++ ++L +F+ LAIGTL+SNA+FQLIPEA
Sbjct: 151 VEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEA 210
Query: 119 FGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQN--GHTHFGNDNFGPQEKTH 176
FGF+P D YV K+ VFGGFYL FF E++LK+LLK ++ GH+H+ +++ P +K
Sbjct: 211 FGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESL-PSKKDQ 269
Query: 177 QPKALPAI-NGVTCYANP--AVTEANGHIHFDNVSVV----SLQDGKKEPSSCTCLKGPK 229
+ + + NG + P +E +G + V+ S+QD + S+C LKG +
Sbjct: 270 EEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVR 329
Query: 230 LSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILL 289
S+IGT+AWMITL D LHNFIDGLAIGAS T+S+ QG+STS+AILCEEFPHELGDFVILL
Sbjct: 330 YSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILL 389
Query: 290 NAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMN 349
NAGMS +QAL FNFLSAC CY+GLAFGIL G++F+ N IFALAGGMFLYISLADMFPEMN
Sbjct: 390 NAGMSIQQALFFNFLSACCCYLGLAFGILAGSHFSANWIFALAGGMFLYISLADMFPEMN 449
Query: 350 DMLREKVTGRKTDFTF-FMIQNAGMLTGFTAILLITLYAGEIEL 392
++ +E RK F+IQN G+LTGFT ++++T+Y+G+I++
Sbjct: 450 EVCQE--DERKGSILIPFIIQNLGLLTGFTIMVVLTMYSGQIQI 491
>gi|205830426 solute carrier family 39 (zinc transporter), member 14
isoform c [Homo sapiens]
Length = 481
Score = 363 bits (932), Expect = e-100
Identities = 190/355 (53%), Positives = 251/355 (70%), Gaps = 18/355 (5%)
Query: 7 CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPC--------EDRPKHKTRPSH 58
C ++ ++F+ H FS ++I SS+ CP +LQQL+ C E+ + RPS
Sbjct: 91 CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRPSA 150
Query: 59 SEVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEA 118
EVWGYG L VT+I+L SLLG + P +KK+++ ++L +F+ LAIGTL+SNA+FQLIPEA
Sbjct: 151 VEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEA 210
Query: 119 FGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQN--GHTHFGNDNFGPQEKTH 176
FGF+P D YV K+ VFGGFYL FF E++LK+LLK ++ GH+H+ +++ P +K
Sbjct: 211 FGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESL-PSKKDQ 269
Query: 177 QPKALPAI-NGVTCYANP--AVTEANGHIHFDNVSVV----SLQDGKKEPSSCTCLKGPK 229
+ + + NG + P +E +G + V+ S+QD + S+C LKG +
Sbjct: 270 EEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVR 329
Query: 230 LSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILL 289
S+IGT+AWMITL D LHNFIDGLAIGAS T+S+ QG+STS+AILCEEFPHELGDFVILL
Sbjct: 330 YSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILL 389
Query: 290 NAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADM 344
NAGMS +QAL FNFLSAC CY+GLAFGIL G++F+ N IFALAGGMFLYISLADM
Sbjct: 390 NAGMSIQQALFFNFLSACCCYLGLAFGILAGSHFSANWIFALAGGMFLYISLADM 444
>gi|115430259 solute carrier family 39 (zinc transporter), member 4
isoform 1 [Homo sapiens]
Length = 622
Score = 184 bits (466), Expect = 2e-46
Identities = 130/407 (31%), Positives = 200/407 (49%), Gaps = 54/407 (13%)
Query: 7 CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPC--EDRPKHKTRPSHSEVWGY 64
CL+A ++ + +G S +T ++ + PA+LQQ C + RP + + S SE + Y
Sbjct: 245 CLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLSQSERYLY 304
Query: 65 GFLSVTIINLASLLGLILTPLIK-KSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDP 123
G L+ +I L ++ GL+L + IL F+ LA+G L +A+ L P+ G
Sbjct: 305 GSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVLGLHT 364
Query: 124 KVDSYVE-----KAVAVFGGFYLLFFFERMLKMLL--------------KTYGQNGHTHF 164
+ + + +A+ G Y F FE + +LL ++ GH+H
Sbjct: 365 HSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDGPCGHSSHSHGGHSHG 424
Query: 165 GNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTC 224
+ P E QPK P G D V+ S + EP +
Sbjct: 425 VSLQLAPSE-LRQPK--PPHEGSRA---------------DLVAEESPELLNPEPRRLS- 465
Query: 225 LKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGD 284
E+ + +MITL DA+HNF DGLA+GA+ S GL+TS+A+ C E PHELGD
Sbjct: 466 ------PELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGD 519
Query: 285 FVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVG-NNFAPNIIFALAGGMFLYISLAD 343
F LL+AG+S RQALL N SA + + GL + VG + + I A+A G+FLY++L D
Sbjct: 520 FAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAWILAVATGLFLYVALCD 579
Query: 344 MFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITLYAGEI 390
M P M + + + F++ N G+L G+T +LL++LY +I
Sbjct: 580 MLPAMLKVRDPR------PWLLFLLHNVGLLGGWTVLLLLSLYEDDI 620
>gi|115430255 solute carrier family 39 (zinc transporter), member 4
isoform 2 [Homo sapiens]
Length = 647
Score = 184 bits (466), Expect = 2e-46
Identities = 130/407 (31%), Positives = 200/407 (49%), Gaps = 54/407 (13%)
Query: 7 CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPC--EDRPKHKTRPSHSEVWGY 64
CL+A ++ + +G S +T ++ + PA+LQQ C + RP + + S SE + Y
Sbjct: 270 CLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLSQSERYLY 329
Query: 65 GFLSVTIINLASLLGLILTPLIK-KSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDP 123
G L+ +I L ++ GL+L + IL F+ LA+G L +A+ L P+ G
Sbjct: 330 GSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVLGLHT 389
Query: 124 KVDSYVE-----KAVAVFGGFYLLFFFERMLKMLL--------------KTYGQNGHTHF 164
+ + + +A+ G Y F FE + +LL ++ GH+H
Sbjct: 390 HSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDGPCGHSSHSHGGHSHG 449
Query: 165 GNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTC 224
+ P E QPK P G D V+ S + EP +
Sbjct: 450 VSLQLAPSE-LRQPK--PPHEGSRA---------------DLVAEESPELLNPEPRRLS- 490
Query: 225 LKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGD 284
E+ + +MITL DA+HNF DGLA+GA+ S GL+TS+A+ C E PHELGD
Sbjct: 491 ------PELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGD 544
Query: 285 FVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVG-NNFAPNIIFALAGGMFLYISLAD 343
F LL+AG+S RQALL N SA + + GL + VG + + I A+A G+FLY++L D
Sbjct: 545 FAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAWILAVATGLFLYVALCD 604
Query: 344 MFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITLYAGEI 390
M P M + + + F++ N G+L G+T +LL++LY +I
Sbjct: 605 MLPAMLKVRDPR------PWLLFLLHNVGLLGGWTVLLLLSLYEDDI 645
>gi|223633939 solute carrier family 39 (zinc transporter), member 12
isoform 1 [Homo sapiens]
Length = 691
Score = 180 bits (456), Expect = 2e-45
Identities = 128/420 (30%), Positives = 212/420 (50%), Gaps = 72/420 (17%)
Query: 7 CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKH---KTRPSHSEVWG 63
C +A ++ + + I+ F + P ++QQL C PK K P+ E +G
Sbjct: 310 CFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCH-LPKDQQAKLPPTTLEKYG 368
Query: 64 YGFLSVTIINLASLLG--LILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEA--- 118
Y ++VT++ L S+LG L+L +++Y IL FVGLA+GTL +A+ LIP+
Sbjct: 369 YSTVAVTLLTLGSMLGTALVLFHSCEENY-RLILQLFVGLAVGTLSGDALLHLIPQVLGL 427
Query: 119 -------FGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGP 171
FG + ++ K + + GG + F E+ +L+ P
Sbjct: 428 HKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLV----------------SP 471
Query: 172 QEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGP--- 228
+K + L +NG +++ H S +S Q G+ + +S LK P
Sbjct: 472 NDK----QGLSLVNGHVGHSH----------HLALNSELSDQAGRGKSASTIQLKSPEDS 517
Query: 229 ---------------KLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAI 273
K I +A MI + D+LHNF DGLAIGA+ + S G++T+IAI
Sbjct: 518 QAAEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAI 577
Query: 274 LCEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILV-GNNFAPNIIFALA 332
LC E PHE+GDF +LL++G+S + A+L NF+S+ + ++GL G+ V + + IF +
Sbjct: 578 LCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVT 637
Query: 333 GGMFLYISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITLYAGEIEL 392
GMFLY+SL +M PEM + ++ + F++QN G++ G+ ++LL+ +Y I++
Sbjct: 638 AGMFLYLSLVEMLPEMTHVQTQR------PWMMFLLQNFGLILGWLSLLLLAIYEQNIKI 691
>gi|223633937 solute carrier family 39 (zinc transporter), member 12
isoform 2 [Homo sapiens]
Length = 654
Score = 172 bits (435), Expect = 6e-43
Identities = 118/402 (29%), Positives = 195/402 (48%), Gaps = 73/402 (18%)
Query: 7 CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKH---KTRPSHSEVWG 63
C +A ++ + + I+ F + P ++QQL C PK K P+ E +G
Sbjct: 310 CFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCH-LPKDQQAKLPPTTLEKYG 368
Query: 64 YGFLSVTIINLASLLG--LILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEA--- 118
Y ++VT++ L S+LG L+L +++Y IL FVGLA+GTL +A+ LIP+
Sbjct: 369 YSTVAVTLLTLGSMLGTALVLFHSCEENY-RLILQLFVGLAVGTLSGDALLHLIPQVLGL 427
Query: 119 -------FGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGP 171
FG + ++ K + + GG + F E+ +L+ ND P
Sbjct: 428 HKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSP----------NDKKSP 477
Query: 172 QEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLS 231
++ + P K
Sbjct: 478 EDS---------------------------------------QAAEMPIGSMTASNRKCK 498
Query: 232 EIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNA 291
I +A MI + D+LHNF DGLAIGA+ + S G++T+IAILC E PHE+GDF +LL++
Sbjct: 499 AISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSS 558
Query: 292 GMSTRQALLFNFLSACSCYVGLAFGILV-GNNFAPNIIFALAGGMFLYISLADMFPEMND 350
G+S + A+L NF+S+ + ++GL G+ V + + IF + GMFLY+SL +M PEM
Sbjct: 559 GLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTH 618
Query: 351 MLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITLYAGEIEL 392
+ ++ + F++QN G++ G+ ++LL+ +Y I++
Sbjct: 619 VQTQR------PWMMFLLQNFGLILGWLSLLLLAIYEQNIKI 654
>gi|153252201 solute carrier family 39 (zinc transporter), member 6
isoform 1 [Homo sapiens]
Length = 755
Score = 155 bits (392), Expect = 6e-38
Identities = 79/161 (49%), Positives = 112/161 (69%), Gaps = 6/161 (3%)
Query: 233 IGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAG 292
+ T+AWM+ + D LHNF DGLAIGA+ T L GLSTS+A+ C E PHELGDF +LL AG
Sbjct: 592 VATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAG 651
Query: 293 MSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI---IFALAGGMFLYISLADMFPEMN 349
M+ +QA+L+N LSA Y+G+A GI +G ++A N+ IFAL G+F+Y++L DM PEM
Sbjct: 652 MTVKQAVLYNALSAMLAYLGMATGIFIG-HYAENVSMWIFALTAGLFMYVALVDMVPEM- 709
Query: 350 DMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITLYAGEI 390
+ + + + +F +QNAGML GF +LLI+++ +I
Sbjct: 710 -LHNDASDHGCSRWGYFFLQNAGMLLGFGIMLLISIFEHKI 749
Score = 79.3 bits (194), Expect = 5e-15
Identities = 41/139 (29%), Positives = 73/139 (52%), Gaps = 6/139 (4%)
Query: 6 QCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRP------SHS 59
+C A ++ + HG + +++F+ +CPA++ Q++ C K S
Sbjct: 263 ECFNASKLLTSHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSLQ 322
Query: 60 EVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAF 119
W GF++++II+ SLLG+IL PL+ + +F +L+F V LA+GTL +A L+P +
Sbjct: 323 IAWVGGFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSH 382
Query: 120 GFDPKVDSYVEKAVAVFGG 138
S+ E A+ + G
Sbjct: 383 ASHHHSHSHEEPAMEMKRG 401
>gi|187936949 solute carrier family 39 (zinc transporter), member 10
[Homo sapiens]
Length = 831
Score = 150 bits (378), Expect = 2e-36
Identities = 81/172 (47%), Positives = 107/172 (62%), Gaps = 6/172 (3%)
Query: 224 CLKGPKLSEIG--TIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHE 281
C G L E G IAWM+ + D +HNF DGLAIGA+ + L G+STSIA+ C E PHE
Sbjct: 655 CHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHE 714
Query: 282 LGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI---IFALAGGMFLY 338
LGDF +LL AGM+ +QA+++N LSA Y+G+ G VG +A NI IFA+ GMFLY
Sbjct: 715 LGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVG-QYANNITLWIFAVTAGMFLY 773
Query: 339 ISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITLYAGEI 390
++L DM PEM + F++QN G+L GF +L+I LY +I
Sbjct: 774 VALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKI 825
Score = 87.0 bits (214), Expect = 3e-17
Identities = 58/194 (29%), Positives = 89/194 (45%), Gaps = 38/194 (19%)
Query: 4 HAQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPC---------EDRPKHKT 54
H +CL ++ +G + I++ F+ +CPA+L Q++ C ED K K
Sbjct: 334 HHECLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKN 393
Query: 55 RPSHSEV------WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFS 108
E W G +S+T+I+L SLLG+IL P+I + F +LTF V LA+GT+
Sbjct: 394 LVPEDEANIGASAWICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMSG 453
Query: 109 NAIFQLIPEAFG----------------------FDPKVDSYVEKAVAVFGGFYLLFFFE 146
+A+ L+P + G F + D+ V K + GG YLLF E
Sbjct: 454 DALLHLLPHSQGGHDHSHQHAHGHGHSHGHESNKFLEEYDA-VLKGLVALGGIYLLFIIE 512
Query: 147 RMLKMLLKTYGQNG 160
++M Q G
Sbjct: 513 HCIRMFKHYKQQRG 526
>gi|55741750 solute carrier family 39 (zinc transporter), member 10
[Homo sapiens]
Length = 831
Score = 150 bits (378), Expect = 2e-36
Identities = 81/172 (47%), Positives = 107/172 (62%), Gaps = 6/172 (3%)
Query: 224 CLKGPKLSEIG--TIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHE 281
C G L E G IAWM+ + D +HNF DGLAIGA+ + L G+STSIA+ C E PHE
Sbjct: 655 CHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHE 714
Query: 282 LGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI---IFALAGGMFLY 338
LGDF +LL AGM+ +QA+++N LSA Y+G+ G VG +A NI IFA+ GMFLY
Sbjct: 715 LGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVG-QYANNITLWIFAVTAGMFLY 773
Query: 339 ISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITLYAGEI 390
++L DM PEM + F++QN G+L GF +L+I LY +I
Sbjct: 774 VALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKI 825
Score = 87.0 bits (214), Expect = 3e-17
Identities = 58/194 (29%), Positives = 89/194 (45%), Gaps = 38/194 (19%)
Query: 4 HAQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPC---------EDRPKHKT 54
H +CL ++ +G + I++ F+ +CPA+L Q++ C ED K K
Sbjct: 334 HHECLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKN 393
Query: 55 RPSHSEV------WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFS 108
E W G +S+T+I+L SLLG+IL P+I + F +LTF V LA+GT+
Sbjct: 394 LVPEDEANIGASAWICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMSG 453
Query: 109 NAIFQLIPEAFG----------------------FDPKVDSYVEKAVAVFGGFYLLFFFE 146
+A+ L+P + G F + D+ V K + GG YLLF E
Sbjct: 454 DALLHLLPHSQGGHDHSHQHAHGHGHSHGHESNKFLEEYDA-VLKGLVALGGIYLLFIIE 512
Query: 147 RMLKMLLKTYGQNG 160
++M Q G
Sbjct: 513 HCIRMFKHYKQQRG 526
>gi|206597541 solute carrier family 39 (metal ion transporter),
member 5 [Homo sapiens]
Length = 540
Score = 142 bits (358), Expect = 5e-34
Identities = 119/407 (29%), Positives = 179/407 (43%), Gaps = 54/407 (13%)
Query: 2 HQHAQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEV 61
H + CL ++ G S A +T +F+++CPA+L Q++ C P
Sbjct: 153 HLNEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSA 212
Query: 62 WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAF-- 119
L+V +++L S L L+L L+ +L F LA+GTL +A+ L+P A
Sbjct: 213 LLQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEG 272
Query: 120 -----GFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEK 174
G P+ D + ++V GG +LLF E ML +L H + +
Sbjct: 273 RHAGPGGLPEKD--LGPGLSVLGGLFLLFVLENMLGLLR-------HRGLRPRCCRRKRR 323
Query: 175 THQPKALPAINGVTCYANP--AVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSE 232
+ + L NG P A E G++E +S P L+
Sbjct: 324 NLETRNLDPENGSGMALQPLQAAPEPGAQ-------------GQREKNS---QHPPALAP 367
Query: 233 IG------------TIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPH 280
G I WM+ L D LHN DGLAIGA+ + GLST++A+ C E PH
Sbjct: 368 PGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPH 427
Query: 281 ELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI--IFALAGGMFLY 338
ELGDF +LL +G+S R+ LL + +S G G+ + P +F + G+FLY
Sbjct: 428 ELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLY 487
Query: 339 ISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITL 385
++L DM P +LR ++Q G+L G +L ITL
Sbjct: 488 VALVDMLPA---LLRPP---EPLPTPHVLLQGLGLLLGGGLMLAITL 528
>gi|206597539 solute carrier family 39 (metal ion transporter),
member 5 [Homo sapiens]
Length = 540
Score = 142 bits (358), Expect = 5e-34
Identities = 119/407 (29%), Positives = 179/407 (43%), Gaps = 54/407 (13%)
Query: 2 HQHAQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEV 61
H + CL ++ G S A +T +F+++CPA+L Q++ C P
Sbjct: 153 HLNEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSA 212
Query: 62 WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAF-- 119
L+V +++L S L L+L L+ +L F LA+GTL +A+ L+P A
Sbjct: 213 LLQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEG 272
Query: 120 -----GFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEK 174
G P+ D + ++V GG +LLF E ML +L H + +
Sbjct: 273 RHAGPGGLPEKD--LGPGLSVLGGLFLLFVLENMLGLLR-------HRGLRPRCCRRKRR 323
Query: 175 THQPKALPAINGVTCYANP--AVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSE 232
+ + L NG P A E G++E +S P L+
Sbjct: 324 NLETRNLDPENGSGMALQPLQAAPEPGAQ-------------GQREKNS---QHPPALAP 367
Query: 233 IG------------TIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPH 280
G I WM+ L D LHN DGLAIGA+ + GLST++A+ C E PH
Sbjct: 368 PGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPH 427
Query: 281 ELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI--IFALAGGMFLY 338
ELGDF +LL +G+S R+ LL + +S G G+ + P +F + G+FLY
Sbjct: 428 ELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLY 487
Query: 339 ISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITL 385
++L DM P +LR ++Q G+L G +L ITL
Sbjct: 488 VALVDMLPA---LLRPP---EPLPTPHVLLQGLGLLLGGGLMLAITL 528
>gi|153252214 solute carrier family 39 (zinc transporter), member 6
isoform 2 [Homo sapiens]
Length = 433
Score = 132 bits (331), Expect = 7e-31
Identities = 63/115 (54%), Positives = 85/115 (73%), Gaps = 4/115 (3%)
Query: 233 IGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAG 292
+ T+AWM+ + D LHNF DGLAIGA+ T L GLSTS+A+ C E PHELGDF +LL AG
Sbjct: 317 VATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAG 376
Query: 293 MSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI---IFALAGGMFLYISLADM 344
M+ +QA+L+N LSA Y+G+A GI +G ++A N+ IFAL G+F+Y++L DM
Sbjct: 377 MTVKQAVLYNALSAMLAYLGMATGIFIG-HYAENVSMWIFALTAGLFMYVALVDM 430
Score = 69.3 bits (168), Expect = 6e-12
Identities = 37/120 (30%), Positives = 65/120 (54%), Gaps = 6/120 (5%)
Query: 25 ITSSKFSVICPAVLQQLNFHPCEDRPKHKTRP------SHSEVWGYGFLSVTIINLASLL 78
+ +++F+ +CPA++ Q++ C K S W GF++++II+ SLL
Sbjct: 7 LNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSLQIAWVGGFIAISIISFLSLL 66
Query: 79 GLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPKVDSYVEKAVAVFGG 138
G+IL PL+ + +F +L+F V LA+GTL +A L+P + S+ E A+ + G
Sbjct: 67 GVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPAMEMKRG 126
>gi|117553619 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 84.7 bits (208), Expect = 1e-16
Identities = 89/355 (25%), Positives = 144/355 (40%), Gaps = 55/355 (15%)
Query: 61 VWGYGFLSVTIINLASLLGLILTPLIKKS-YFPKILTFFVGLAIGTLFSNAIFQLIPEAF 119
+W Y + +I+ A L L P+ S +L + A G L +A LIP A
Sbjct: 134 LWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHAL 193
Query: 120 GFDPKVDSYVEK----------------AVAVFGGFYLLFFFERMLKMLLKTYGQN---G 160
+P +E+ + V G E+ ++ + +G + G
Sbjct: 194 --EPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHG 251
Query: 161 HTHF---GNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKK 217
H H G+ G QE++ + K + E G S V +DG
Sbjct: 252 HAHSHTRGSHGHGRQERSTKEKQS---------SEEEEKETRGVQKRRGGSTVP-KDGPV 301
Query: 218 EPSSCTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEE 277
P + K + ++ ++ D HNF DGLAIGAS G+ T++ +L E
Sbjct: 302 RPQNAEEEK--RGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHE 359
Query: 278 FPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGIL-----VGNNFA----PNII 328
PHE+GDF IL+ +G S +QA+ L+A G A +L VG+ A P +
Sbjct: 360 VPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWV 419
Query: 329 FALAGGMFLYISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLI 383
G F+Y++ + PE +LRE + +++ G+L G ++LI
Sbjct: 420 LPFTAGGFIYVATVSVLPE---LLREASPLQS------LLEVLGLLGGVIMMVLI 465
>gi|117553608 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 84.7 bits (208), Expect = 1e-16
Identities = 89/355 (25%), Positives = 144/355 (40%), Gaps = 55/355 (15%)
Query: 61 VWGYGFLSVTIINLASLLGLILTPLIKKS-YFPKILTFFVGLAIGTLFSNAIFQLIPEAF 119
+W Y + +I+ A L L P+ S +L + A G L +A LIP A
Sbjct: 134 LWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHAL 193
Query: 120 GFDPKVDSYVEK----------------AVAVFGGFYLLFFFERMLKMLLKTYGQN---G 160
+P +E+ + V G E+ ++ + +G + G
Sbjct: 194 --EPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHG 251
Query: 161 HTHF---GNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKK 217
H H G+ G QE++ + K + E G S V +DG
Sbjct: 252 HAHSHTRGSHGHGRQERSTKEKQS---------SEEEEKETRGVQKRRGGSTVP-KDGPV 301
Query: 218 EPSSCTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEE 277
P + K + ++ ++ D HNF DGLAIGAS G+ T++ +L E
Sbjct: 302 RPQNAEEEK--RGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHE 359
Query: 278 FPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGIL-----VGNNFA----PNII 328
PHE+GDF IL+ +G S +QA+ L+A G A +L VG+ A P +
Sbjct: 360 VPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWV 419
Query: 329 FALAGGMFLYISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLI 383
G F+Y++ + PE +LRE + +++ G+L G ++LI
Sbjct: 420 LPFTAGGFIYVATVSVLPE---LLREASPLQS------LLEVLGLLGGVIMMVLI 465
>gi|40255101 solute carrier family 39 (zinc transporter), member 13
isoform b [Homo sapiens]
Length = 364
Score = 73.9 bits (180), Expect = 2e-13
Identities = 75/307 (24%), Positives = 117/307 (38%), Gaps = 57/307 (18%)
Query: 60 EVWGYGFLSVTIINLASLLGLILTPL-----IKKSYFPKILTFFVGLAIGTLFSNAIFQL 114
+ W L ++ L+ + L++ PL ++ L + A+G L N L
Sbjct: 66 DTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSFALGGLLGNVFLHL 125
Query: 115 IPEAFGFD---------PKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFG 165
+PEA+ + + + + V G E KM L + + G
Sbjct: 126 LPEAWAYTCSASPGGEGQSLQQQQQLGLWVIAGILTFLALE---KMFLDSKEE------G 176
Query: 166 NDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCL 225
++ T A A+NG C A PA EP +
Sbjct: 177 TSQAPNKDPT---AAAAALNGGHCLAQPAA----------------------EPGLGAVV 211
Query: 226 KGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDF 285
+ K+S ++ L + + NF GLA+ AS +S GL T++AIL E PHE+GDF
Sbjct: 212 RSIKVS-----GYLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDF 266
Query: 286 VILLNAGMSTRQALLFNFLSACSCYVGLAFGILV----GNNFAPNIIFALAGGMFLYISL 341
ILL AG A +A +G F I G + G FLYI+L
Sbjct: 267 AILLRAGFDRWSAAKLQLSTALGGLLGAGFAICTQSPKGVEETAAWVLPFTSGGFLYIAL 326
Query: 342 ADMFPEM 348
++ P++
Sbjct: 327 VNVLPDL 333
>gi|190014617 solute carrier family 39 (zinc transporter), member 13
isoform a [Homo sapiens]
Length = 371
Score = 71.6 bits (174), Expect = 1e-12
Identities = 77/314 (24%), Positives = 121/314 (38%), Gaps = 64/314 (20%)
Query: 60 EVWGYGFLSVTIINLASLLGLILTPL-----IKKSYFPKILTFFVGLAIGTLFSNAIFQL 114
+ W L ++ L+ + L++ PL ++ L + A+G L N L
Sbjct: 66 DTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSFALGGLLGNVFLHL 125
Query: 115 IPEAFGFD---------PKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFG 165
+PEA+ + + + + V G E KM L + + G
Sbjct: 126 LPEAWAYTCSASPGGEGQSLQQQQQLGLWVIAGILTFLALE---KMFLDSKEE------G 176
Query: 166 NDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCL 225
++ T A A+NG C A PA EP +
Sbjct: 177 TSQAPNKDPT---AAAAALNGGHCLAQPAA----------------------EPGLGAVV 211
Query: 226 KGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDF 285
+ K+S ++ L + + NF GLA+ AS +S GL T++AIL E PHE+GDF
Sbjct: 212 RSIKVS-----GYLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDF 266
Query: 286 VILLNAGMSTRQALLFNFLSACSCYVGLAFGI-------LVGNNFAPN----IIFALAGG 334
ILL AG A +A +G F I +VG + A + G
Sbjct: 267 AILLRAGFDRWSAAKLQLSTALGGLLGAGFAICTQSPKGVVGCSPAAEETAAWVLPFTSG 326
Query: 335 MFLYISLADMFPEM 348
FLYI+L ++ P++
Sbjct: 327 GFLYIALVNVLPDL 340
>gi|156415986 solute carrier family 39 (zinc transporter), member 2
[Homo sapiens]
Length = 309
Score = 42.7 bits (99), Expect = 6e-04
Identities = 32/117 (27%), Positives = 57/117 (48%), Gaps = 9/117 (7%)
Query: 237 AWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTR 296
A ++ L + H+ +GLA+G T++ L +A+L + G + L++ G S+R
Sbjct: 165 ALVLLLSLSFHSVFEGLAVGLQPTVAATVQLC--LAVLAHKGLVVFGVGMRLVHLGTSSR 222
Query: 297 QALLFNFLSACSCYVGLAFGILV-------GNNFAPNIIFALAGGMFLYISLADMFP 346
A+ L A +GLA G+ V G A ++ +A G FLY++ ++ P
Sbjct: 223 WAVFSILLLALMSPLGLAVGLAVTGGDSEGGRGLAQAVLEGVAAGTFLYVTFLEILP 279
>gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo
sapiens]
Length = 342
Score = 42.0 bits (97), Expect = 0.001
Identities = 38/134 (28%), Positives = 60/134 (44%), Gaps = 19/134 (14%)
Query: 230 LSEIGTIAW----MITLCDALHNFIDGLAIG---------ASCTLSLLQGLSTSIAILCE 276
L++ G +W ++ L +HN +GLA+G AS T + L+ I I +
Sbjct: 183 LAQPGGSSWRRIALLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGI--Q 240
Query: 277 EFPHELGDFVILLNAGMSTRQALLFNFLSAC---SCYVGLAFGILVGNNFAPNIIFALAG 333
FP L + L AG ST +A + LS V AF +++ P + A A
Sbjct: 241 NFPEGLAVSLPLRGAGFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYAL-AFAA 299
Query: 334 GMFLYISLADMFPE 347
G +Y+ + D+ PE
Sbjct: 300 GAMVYVVMDDIIPE 313
>gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo
sapiens]
Length = 335
Score = 42.0 bits (97), Expect = 0.001
Identities = 38/134 (28%), Positives = 60/134 (44%), Gaps = 19/134 (14%)
Query: 230 LSEIGTIAW----MITLCDALHNFIDGLAIG---------ASCTLSLLQGLSTSIAILCE 276
L++ G +W ++ L +HN +GLA+G AS T + L+ I I +
Sbjct: 176 LAQPGGSSWRRIALLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGI--Q 233
Query: 277 EFPHELGDFVILLNAGMSTRQALLFNFLSAC---SCYVGLAFGILVGNNFAPNIIFALAG 333
FP L + L AG ST +A + LS V AF +++ P + A A
Sbjct: 234 NFPEGLAVSLPLRGAGFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYAL-AFAA 292
Query: 334 GMFLYISLADMFPE 347
G +Y+ + D+ PE
Sbjct: 293 GAMVYVVMDDIIPE 306
>gi|40254928 solute carrier family 39 (zinc transporter), member 9
[Homo sapiens]
Length = 307
Score = 33.5 bits (75), Expect = 0.34
Identities = 32/118 (27%), Positives = 54/118 (45%), Gaps = 10/118 (8%)
Query: 241 TLCDALHNFIDGLAIGASCTLSLLQ-GLSTSIAILCEEFPHELGDFVILLNAGMST---R 296
TL +H DG+A+GA+ + S L +AI+ + P G L++AG+ R
Sbjct: 149 TLGLVVHAAADGVALGAAASTSQTSVQLIVFVAIMLHKAPAAFGLVSFLMHAGLERNRIR 208
Query: 297 QALLFNFLSA----CSCYVGLAFGI--LVGNNFAPNIIFALAGGMFLYISLADMFPEM 348
+ LL L+A Y+GL+ + A + + G FLY++ + PE+
Sbjct: 209 KHLLVFALAAPVMSMVTYLGLSKSSKEALSEVNATGVAMLFSAGTFLYVATVHVLPEV 266
>gi|21361423 solute carrier family 39 (zinc transporter), member 1
[Homo sapiens]
Length = 324
Score = 33.5 bits (75), Expect = 0.34
Identities = 23/109 (21%), Positives = 50/109 (45%), Gaps = 8/109 (7%)
Query: 245 ALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFL 304
ALH+ +GLA+G + + + +A+L + + + LL + + + L
Sbjct: 188 ALHSVFEGLAVGLQRDRA--RAMELCLALLLHKGILAVSLSLRLLQSHLRAQVVAGCGIL 245
Query: 305 SACSCYVGLAFGILVGNNFAP------NIIFALAGGMFLYISLADMFPE 347
+C +G+ G + + P +++ +A G FLYI+ ++ P+
Sbjct: 246 FSCMTPLGIGLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQ 294
>gi|122937259 solute carrier family 45, member 4 [Homo sapiens]
Length = 798
Score = 30.0 bits (66), Expect = 3.8
Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 13/76 (17%)
Query: 49 RPKHKTRPSHSEVWGYG------FLSVTIINLASLLGLILTPLIKKSYFPKILT------ 96
RPK P S W + S+T L+ +LGLI TPLI + L+
Sbjct: 12 RPKTLVSPLRSNQWSLQKGLPEQYYSLTWF-LSPILGLIFTPLIGSASDRCTLSWGRRRP 70
Query: 97 FFVGLAIGTLFSNAIF 112
F + L +G LF A+F
Sbjct: 71 FILALCVGVLFGVALF 86
>gi|27262624 ATP-binding cassette, sub-family A , member 5 [Homo
sapiens]
Length = 1642
Score = 29.6 bits (65), Expect = 4.9
Identities = 18/40 (45%), Positives = 24/40 (60%), Gaps = 1/40 (2%)
Query: 66 FLSVTIINLASLL-GLILTPLIKKSYFPKILTFFVGLAIG 104
FL + L+S+ L+LTPL KKS I+ FFV +A G
Sbjct: 300 FLLFFLYGLSSVFFALMLTPLFKKSKHVGIVEFFVTVAFG 339
>gi|27262626 ATP-binding cassette, sub-family A , member 5 [Homo
sapiens]
Length = 1642
Score = 29.6 bits (65), Expect = 4.9
Identities = 18/40 (45%), Positives = 24/40 (60%), Gaps = 1/40 (2%)
Query: 66 FLSVTIINLASLL-GLILTPLIKKSYFPKILTFFVGLAIG 104
FL + L+S+ L+LTPL KKS I+ FFV +A G
Sbjct: 300 FLLFFLYGLSSVFFALMLTPLFKKSKHVGIVEFFVTVAFG 339
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.140 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,359,049
Number of Sequences: 37866
Number of extensions: 600701
Number of successful extensions: 1498
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1392
Number of HSP's gapped (non-prelim): 53
length of query: 393
length of database: 18,247,518
effective HSP length: 104
effective length of query: 289
effective length of database: 14,309,454
effective search space: 4135432206
effective search space used: 4135432206
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.