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Search of human proteins with 196115141
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|196115141 CDKN1A interacting zinc finger protein 1 isoform 2
[Homo sapiens]
(842 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|196115141 CDKN1A interacting zinc finger protein 1 isoform 2 ... 1707 0.0
gi|196115153 CDKN1A interacting zinc finger protein 1 isoform 3 ... 1692 0.0
gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1 ... 1677 0.0
gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1 [... 1677 0.0
gi|196115158 CDKN1A interacting zinc finger protein 1 isoform 4 ... 1645 0.0
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 89 2e-17
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 80 6e-15
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 79 2e-14
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 76 1e-13
gi|56549696 E1A binding protein p400 [Homo sapiens] 74 6e-13
gi|38788274 bromodomain PHD finger transcription factor isoform ... 70 1e-11
gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 67 7e-11
gi|38788260 bromodomain PHD finger transcription factor isoform ... 66 2e-10
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 65 2e-10
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 65 2e-10
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 65 2e-10
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 65 2e-10
gi|163965366 nascent polypeptide-associated complex alpha subuni... 65 2e-10
gi|62953127 polyhomeotic 1-like [Homo sapiens] 64 4e-10
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 64 6e-10
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo... 64 6e-10
gi|221139761 zinc finger protein 853 [Homo sapiens] 64 8e-10
gi|110349719 titin isoform N2-A [Homo sapiens] 64 8e-10
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 63 1e-09
gi|197276594 RNA binding motif protein 20 [Homo sapiens] 63 1e-09
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 63 1e-09
gi|58530845 zyxin [Homo sapiens] 62 2e-09
gi|4508047 zyxin [Homo sapiens] 62 2e-09
gi|146134388 YLP motif containing 1 [Homo sapiens] 62 2e-09
gi|33286444 mastermind-like 2 [Homo sapiens] 62 3e-09
>gi|196115141 CDKN1A interacting zinc finger protein 1 isoform 2
[Homo sapiens]
Length = 842
Score = 1707 bits (4421), Expect = 0.0
Identities = 842/842 (100%), Positives = 842/842 (100%)
Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP
Sbjct: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG
Sbjct: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN
Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
Query: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK
Sbjct: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
Query: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300
EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP
Sbjct: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300
Query: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360
EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ
Sbjct: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360
Query: 361 VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 420
VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP
Sbjct: 361 VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 420
Query: 421 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR 480
EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR
Sbjct: 421 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR 480
Query: 481 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY 540
EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY
Sbjct: 481 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY 540
Query: 541 ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC 600
ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC
Sbjct: 541 ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC 600
Query: 601 NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL 660
NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL
Sbjct: 601 NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL 660
Query: 661 KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW 720
KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW
Sbjct: 661 KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW 720
Query: 721 KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN 780
KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN
Sbjct: 721 KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN 780
Query: 781 PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL 840
PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL
Sbjct: 781 PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL 840
Query: 841 KT 842
KT
Sbjct: 841 KT 842
>gi|196115153 CDKN1A interacting zinc finger protein 1 isoform 3
[Homo sapiens]
Length = 837
Score = 1692 bits (4382), Expect = 0.0
Identities = 837/842 (99%), Positives = 837/842 (99%), Gaps = 5/842 (0%)
Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP
Sbjct: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG
Sbjct: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN
Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
Query: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
PQKQARTSSSTTPNRK TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK
Sbjct: 181 PQKQARTSSSTTPNRK-----TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 235
Query: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300
EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP
Sbjct: 236 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 295
Query: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360
EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ
Sbjct: 296 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 355
Query: 361 VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 420
VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP
Sbjct: 356 VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 415
Query: 421 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR 480
EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR
Sbjct: 416 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR 475
Query: 481 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY 540
EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY
Sbjct: 476 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY 535
Query: 541 ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC 600
ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC
Sbjct: 536 ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC 595
Query: 601 NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL 660
NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL
Sbjct: 596 NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL 655
Query: 661 KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW 720
KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW
Sbjct: 656 KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW 715
Query: 721 KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN 780
KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN
Sbjct: 716 KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN 775
Query: 781 PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL 840
PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL
Sbjct: 776 PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL 835
Query: 841 KT 842
KT
Sbjct: 836 KT 837
>gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1
[Homo sapiens]
Length = 898
Score = 1677 bits (4343), Expect = 0.0
Identities = 842/898 (93%), Positives = 842/898 (93%), Gaps = 56/898 (6%)
Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP
Sbjct: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG
Sbjct: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN
Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
Query: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK
Sbjct: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
Query: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300
EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP
Sbjct: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300
Query: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360
EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ
Sbjct: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360
Query: 361 VQPQLQQEAEPQ------------------------------------------------ 372
VQPQLQQEAEPQ
Sbjct: 361 VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ 420
Query: 373 ----KQVQ----PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 424
KQVQ PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP
Sbjct: 421 LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 480
Query: 425 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 484
VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG
Sbjct: 481 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 540
Query: 485 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 544
VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA
Sbjct: 541 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 600
Query: 545 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 604
SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ
Sbjct: 601 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 660
Query: 605 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 664
LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE
Sbjct: 661 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 720
Query: 665 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 724
KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE
Sbjct: 721 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 780
Query: 725 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 784
TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT
Sbjct: 781 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 840
Query: 785 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 842
TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT
Sbjct: 841 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 898
>gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1
[Homo sapiens]
Length = 898
Score = 1677 bits (4343), Expect = 0.0
Identities = 842/898 (93%), Positives = 842/898 (93%), Gaps = 56/898 (6%)
Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP
Sbjct: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG
Sbjct: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN
Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
Query: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK
Sbjct: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
Query: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300
EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP
Sbjct: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300
Query: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360
EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ
Sbjct: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360
Query: 361 VQPQLQQEAEPQ------------------------------------------------ 372
VQPQLQQEAEPQ
Sbjct: 361 VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ 420
Query: 373 ----KQVQ----PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 424
KQVQ PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP
Sbjct: 421 LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 480
Query: 425 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 484
VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG
Sbjct: 481 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 540
Query: 485 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 544
VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA
Sbjct: 541 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 600
Query: 545 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 604
SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ
Sbjct: 601 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 660
Query: 605 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 664
LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE
Sbjct: 661 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 720
Query: 665 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 724
KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE
Sbjct: 721 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 780
Query: 725 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 784
TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT
Sbjct: 781 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 840
Query: 785 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 842
TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT
Sbjct: 841 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 898
>gi|196115158 CDKN1A interacting zinc finger protein 1 isoform 4
[Homo sapiens]
Length = 818
Score = 1645 bits (4260), Expect = 0.0
Identities = 818/842 (97%), Positives = 818/842 (97%), Gaps = 24/842 (2%)
Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP
Sbjct: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG
Sbjct: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG------------------------ 96
Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN
Sbjct: 97 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 156
Query: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK
Sbjct: 157 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 216
Query: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300
EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP
Sbjct: 217 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 276
Query: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360
EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ
Sbjct: 277 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 336
Query: 361 VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 420
VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP
Sbjct: 337 VQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP 396
Query: 421 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR 480
EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR
Sbjct: 397 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR 456
Query: 481 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY 540
EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY
Sbjct: 457 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY 516
Query: 541 ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC 600
ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC
Sbjct: 517 ICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWC 576
Query: 601 NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL 660
NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL
Sbjct: 577 NTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKEL 636
Query: 661 KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW 720
KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW
Sbjct: 637 KSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEW 696
Query: 721 KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN 780
KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN
Sbjct: 697 KGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKN 756
Query: 781 PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL 840
PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL
Sbjct: 757 PSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRL 816
Query: 841 KT 842
KT
Sbjct: 817 KT 818
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 89.0 bits (219), Expect = 2e-17
Identities = 91/324 (28%), Positives = 133/324 (41%), Gaps = 51/324 (15%)
Query: 5 QQQQQLQQQQQQLQQL-------QQQQLQQQQLQQQQLLQLQQLLQQSP---PQAPLPMA 54
Q QQQ+QQQQQQLQ++ QQQQ QQQQ QQQQ LQ Q +QQ P PQ P A
Sbjct: 226 QNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQA 285
Query: 55 VSRGL----------PPQQPQQPLLNLQGTNSASLLNGSMLQRALL--LQQLQGLDQFAM 102
+ + L PP QPQQP + N S L + L+ Q L G +
Sbjct: 286 LPQQLQQMHHTQHHQPPPQPQQPPV---AQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ 342
Query: 103 PPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSL--- 159
PP + A + + + + A + Q+ P +Q + +
Sbjct: 343 PPLKFVRAPMVVQQPPVQP----QVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIR 398
Query: 160 -LGPPPVGVPMNPSQFNLSGRNPQKQARTS-----SSTTPNRKDSSSQTMPVEDKSDPPE 213
PP V PS GR P Q S SS +P ++ + Q+MP PP+
Sbjct: 399 ARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMP-----PPPQ 453
Query: 214 GSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEP 273
S + +P + P P + P+P P+P + S + A+ ++ P+
Sbjct: 454 PSPQPGQPSSQPNSNVSSGPAP---SPSSFLPSPSPQPSQ-SPVTARTPQNFSVPS---- 505
Query: 274 PGQLQVKAQPQARMTVPKQTQTPD 297
PG L P + M+ +Q +
Sbjct: 506 PGPLNTPVNPSSVMSPAGSSQAEE 529
Score = 63.9 bits (154), Expect = 6e-10
Identities = 57/195 (29%), Positives = 90/195 (46%), Gaps = 11/195 (5%)
Query: 246 APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEA 305
AP ++ P +L+ + +++ Q Q + Q QA + +Q Q +A ++
Sbjct: 137 APHSMAVVSTATPQTQLQLQQVALQQQQQQQ-QFQQQQQAALQQQQQQQQQQQF-QAQQS 194
Query: 306 QVLPRFQPRVLQVQA-QVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQ 364
+ +FQ V Q Q Q Q Q Q + Q Q ++Q+Q Q L LQQ+Q Q Q
Sbjct: 195 AMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQ 254
Query: 365 LQQEAEPQK-QVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQT 423
QQ+ + Q Q QP + QP +Q + PP+Q Q +Q H H QP P+Q
Sbjct: 255 QQQQQQQQALQAQPPIQ---QPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQ---PQQP 308
Query: 424 PVVVHVCGLEMPPDA 438
PV + ++PP +
Sbjct: 309 PVAQNQPS-QLPPQS 322
Score = 53.1 bits (126), Expect = 1e-06
Identities = 67/272 (24%), Positives = 100/272 (36%), Gaps = 30/272 (11%)
Query: 152 PQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDP 211
P QSL G P G + + R P + S + P+ P
Sbjct: 81 PMNALQSLTGGPAAGA----AGIGMPPRGPGQSLGGMGSL-------GAMGQPMSLSGQP 129
Query: 212 PEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEK 271
P G+ A M P+ + ++ + + + + + ++ ++
Sbjct: 130 PPGTSGMAPHSMAVVSTAT----PQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQ 185
Query: 272 EPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIP 331
+ Q Q A Q V +Q Q L + + Q L + Q Q Q+Q Q Q
Sbjct: 186 QQQFQAQQSAMQQQFQAVVQQQQ--QLQQQQQQQQHLIKLHH---QNQQQIQQQQQQLQR 240
Query: 332 STDTQVQPKLQKQAQTQTSPEHLVLQQKQVQ-PQLQQEAEPQKQVQPQV-----HTQ-AQ 384
Q+Q + Q+Q Q Q + + Q +Q P +QQ P Q PQ HTQ Q
Sbjct: 241 IAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ 300
Query: 385 PSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVS 416
P QPQ+ P AQ P Q Q TQP VS
Sbjct: 301 PPPQPQQPPVAQ---NQPSQLPPQSQTQPLVS 329
Score = 42.4 bits (98), Expect = 0.002
Identities = 55/205 (26%), Positives = 78/205 (38%), Gaps = 27/205 (13%)
Query: 276 QLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQ-PRVLQVQAQVQSQTQPRIPSTD 334
QLQ + Q Q + + + + Q + + Q + Q Q Q Q Q Q + +
Sbjct: 209 QLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQP 268
Query: 335 TQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQV----------HTQAQ 384
QP +Q Q Q P + QQ Q Q P + QP V +Q Q
Sbjct: 269 PIQQPPMQ---QPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQ 325
Query: 385 PSV-QPQEHPPAQVSVQPP----------EQTHEQPHTQPQVSLLAPEQTPVVVHVCGLE 433
P V Q Q P + QPP +Q QP Q Q + + Q +V G++
Sbjct: 326 PLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMV-APGVQ 384
Query: 434 MPPDAVEAGGGMEKTLPEPVGTQVS 458
M +A+ A GGM P T VS
Sbjct: 385 MITEAL-AQGGMHIRARFPPTTAVS 408
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 80.5 bits (197), Expect = 6e-15
Identities = 125/441 (28%), Positives = 157/441 (35%), Gaps = 53/441 (12%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQL-QQQQLQQQQL--LQLQQLLQQSPPQAPLPMAVSRGLP 60
Q QQQQ QQQQQLQQ QQQQL QQQQLQQQQL Q QQ LQQ Q
Sbjct: 3899 QLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQ 3958
Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
QQ QQ Q LLN S R LL Q Q Q A+ P MP L
Sbjct: 3959 QQQQQQQFQQQQQQQQMGLLNQS---RTLLSPQQQQQQQVALGPG--------MPAKPLQ 4007
Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPP-VGVPMNPSQFNLSGR 179
+ +SPG P+L L P + ++ GP G P+ G
Sbjct: 4008 H-----FSSPGALGPTLL---LTGKEQNTVDPAVSSEATEGPSTHQGGPL------AIGT 4053
Query: 180 NPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIA 239
P+ A P+ SQ + V+ + P S + P + Q
Sbjct: 4054 TPESMATEPGEVKPS-LSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAG 4112
Query: 240 KEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVK----AQPQARMTVPKQT-- 293
EAS +P L + + + PG + QP + T
Sbjct: 4113 GGSHGQLGSGSSSEASSVP--HLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGP 4170
Query: 294 QTPDLLPEALEAQVLP--RFQPRVLQVQAQVQS--QTQPRIPSTDTQVQPKLQKQAQTQT 349
Q P P Q LP P V Q++AQ+Q P++ Q Q +LQ +
Sbjct: 4171 QPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQ 4230
Query: 350 SPEHLVLQQKQVQPQLQQEAEPQKQVQP-QVHTQAQPSV----QPQEHPPAQVSVQPPEQ 404
LQQ Q Q EP Q P Q QP + PQ P ++ P Q
Sbjct: 4231 ------LQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQ 4284
Query: 405 THEQPHTQPQVSLLAPEQTPV 425
+ P P PV
Sbjct: 4285 GPPRLPAPPGALSTGPVLGPV 4305
Score = 72.4 bits (176), Expect = 2e-12
Identities = 111/446 (24%), Positives = 163/446 (36%), Gaps = 63/446 (14%)
Query: 4 QQQQQQLQQQQQQ----LQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAP-----LPMA 54
Q+Q Q+++QQ++ + + + +Q QQQQ QQQQ Q +L SP Q+P LP
Sbjct: 3575 QKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQ 3634
Query: 55 VSRGLPPQQPQQP--------LLNLQGTNSASLLNGSMLQRALLLQQLQ----GLDQFAM 102
+ G Q PQ P L G G L AL QQ Q G A
Sbjct: 3635 LLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAG 3694
Query: 103 PPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQ----LATPNLQQFFPQATRQS 158
P + L LR G S L L Q LA QQ Q +Q
Sbjct: 3695 PSGGFFPGNLA--------LRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQH 3746
Query: 159 LLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKS-DPPEGSEE 217
LLG + Q G Q SS Q + V+ S PP+G +
Sbjct: 3747 LLGQVAI------QQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQG 3800
Query: 218 AAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQL 277
L P + +++ A P+ P +++ ++ P
Sbjct: 3801 M------------LGPAQVAVLQQQHPGALGPQG------PHRQVLMTQSRVLSSPQLAQ 3842
Query: 278 QVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQV 337
Q + R+ +Q Q + L Q ++ Q + QP Q
Sbjct: 3843 QGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQ 3902
Query: 338 QPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQV 397
Q +LQ+Q Q Q + + QQ+Q+Q Q Q+ + Q+Q+Q Q Q Q Q+ Q
Sbjct: 3903 QQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQ-----QQQQQLQQ 3957
Query: 398 SVQPPEQTHEQPHTQPQVSLLAPEQT 423
Q +Q +Q Q Q+ LL +T
Sbjct: 3958 QQQQQQQQFQQQQQQQQMGLLNQSRT 3983
Score = 62.4 bits (150), Expect = 2e-09
Identities = 84/302 (27%), Positives = 117/302 (38%), Gaps = 41/302 (13%)
Query: 130 PGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSS 189
P L+PP +P P+A+R L PPP PM+P P + +R S
Sbjct: 601 PPFEESPLSPPPEESPLSPP--PEASR---LSPPPEDSPMSPPPEESPMSPPPEVSRLSP 655
Query: 190 STTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEP 249
+R + P+ S PPE S P PE L P PED +P P
Sbjct: 656 LPVVSRLSPPPEESPL---SPPPEES-----PTSPPPEASRLSPPPED-----SPTSPPP 702
Query: 250 EPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLP 309
E AS P L S P E+ P L + +PQ + +++ P L P E + P
Sbjct: 703 EDSPASPPPEDSLMSL--PLEESP--LLPLPEEPQ----LCPRSEGPHLSPRPEEPHLSP 754
Query: 310 RFQPRVLQVQA-QVQSQTQPRIPS-TDTQVQPKLQKQAQ---TQTSPEHLVLQQKQVQPQ 364
R + L QA + QP P +P L QA+ PE L L + +P
Sbjct: 755 RPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPH 814
Query: 365 LQQ-EAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQP-PEQTHEQPHTQPQVSLLAPEQ 422
L EP QP+ + + PQ P + P PE++H P + PE+
Sbjct: 815 LSPVPEEPCLSPQPE-----ESHLSPQSEEPC---LSPRPEESHLSPELEKPPLSPRPEK 866
Query: 423 TP 424
P
Sbjct: 867 PP 868
Score = 62.4 bits (150), Expect = 2e-09
Identities = 125/506 (24%), Positives = 180/506 (35%), Gaps = 90/506 (17%)
Query: 2 FSQQQQQQLQQQQQQLQQ----LQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSR 57
+ +QQQQ QQQQQQ QQ L Q +L + QL PPQ P P +
Sbjct: 3595 YRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGP-PGGQAG 3653
Query: 58 GLP--------PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDT 109
GL P QP P LN + L + Q G A P +
Sbjct: 3654 GLRLTPGGMALPGQPGGPFLN------------TALAQQQQQQHSGGAGSLAGPSGGFFP 3701
Query: 110 AGLTMPTATLGNLRGYGMASPGLAAPSL----TPPQLATPNLQQFFPQATRQSLLGPPPV 165
L LR G S L L QLA QQ Q +Q LLG +
Sbjct: 3702 GNLA--------LRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAI 3753
Query: 166 GVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKS-DPPEGSEEAAEPRMD 224
Q G Q SS Q + V+ S PP+G + P
Sbjct: 3754 ------QQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQV 3807
Query: 225 TPEDQDLP-------PCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEP---- 273
Q P P + + + R + + L RL ++++ +++
Sbjct: 3808 AVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQ 3867
Query: 274 ----------------PGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQ 317
GQ ++ AQP + +Q Q + + Q L + Q + LQ
Sbjct: 3868 GSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQ------QLQQQQQLQQQQQQQLQ 3921
Query: 318 VQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQP 377
Q Q+Q Q ++ Q Q + Q+Q Q Q + L QQ+Q Q Q QQ+ Q+Q Q
Sbjct: 3922 QQQQLQQQ---QLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQ---QQQQQM 3975
Query: 378 QVHTQAQPSVQPQEHPPAQVSVQP-----PEQTHEQPHT-QPQVSLLAPEQTPVVVHVCG 431
+ Q++ + PQ+ QV++ P P Q P P + L EQ V V
Sbjct: 3976 GLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSS 4035
Query: 432 LEMPPDAVEAGGGME-KTLPEPVGTQ 456
+ GG + T PE + T+
Sbjct: 4036 EATEGPSTHQGGPLAIGTTPESMATE 4061
Score = 55.5 bits (132), Expect = 2e-07
Identities = 116/472 (24%), Positives = 169/472 (35%), Gaps = 84/472 (17%)
Query: 4 QQQQQQLQQQQQQL-QQLQQQQLQQQQLQQQQLL---QLQQLLQQSP-----------PQ 48
Q++Q QLQQQ+ QL Q+LQQQ QQQQ QQQ LL +QQ QQ P PQ
Sbjct: 3717 QERQLQLQQQRMQLAQKLQQQ--QQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQ 3774
Query: 49 APLPMAVSRGL--------PPQQPQQPL---------------LNLQGTNSASLLNGS-M 84
+P + +GL PPQ PQ L L QG + L+ S +
Sbjct: 3775 GLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRV 3834
Query: 85 LQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLAT 144
L L QQ QGL + T G++ G L + S P A
Sbjct: 3835 LSSPQLAQQGQGLMGHRL--VTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQ 3892
Query: 145 P--NLQQF--FPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSS 200
P +LQQ Q +Q L Q Q+Q + +
Sbjct: 3893 PMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQ 3952
Query: 201 QTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAK 260
Q + + + + ++ + +M P+ +++ P +PAK
Sbjct: 3953 QQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGP--------GMPAK 4004
Query: 261 RLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVL---- 316
L+ P P L K Q T P + EA E + P +
Sbjct: 4005 PLQHFSSPGALGPTLLLTGKEQ---------NTVDPAVSSEATEGPSTHQGGPLAIGTTP 4055
Query: 317 QVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQ 376
+ A + +P + S D+Q+ L Q Q Q P L Q+QP L+ + Q+QV
Sbjct: 4056 ESMATEPGEVKPSL-SGDSQL---LLVQPQPQPQPSSL-----QLQPPLRLPGQQQQQVS 4106
Query: 377 ------PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQ 422
H Q + + QP +QP + Q +LL P+Q
Sbjct: 4107 LLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQ-NLLGPQQ 4157
Score = 48.1 bits (113), Expect = 3e-05
Identities = 72/299 (24%), Positives = 113/299 (37%), Gaps = 30/299 (10%)
Query: 137 LTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTS---SSTTP 193
L+PP +P P+A+R L PPP +P +P L P +++ S +
Sbjct: 449 LSPPPEESPTSPP--PEASR---LSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPL 503
Query: 194 NRKDSSSQTMPVEDKS-DPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPC 252
+ SS P+E+ PPE E P ++TP P E+ +P PE
Sbjct: 504 SPPPESSPFSPLEESPLSPPE--ESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEEL 561
Query: 253 EASELP-AKRLR-SSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPR 310
S P A RL EE PP + + P+A P ++P L P E+ + P
Sbjct: 562 PTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESP-LSPPPEESPLSP- 619
Query: 311 FQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAE 370
S+ P P D+ + P +++ PE L V +L E
Sbjct: 620 ---------PPEASRLSP--PPEDSPMSPP-PEESPMSPPPEVSRLSPLPVVSRLSPPPE 667
Query: 371 PQKQVQPQVHTQAQPSVQPQE-HPPAQVS--VQPPEQTHEQPHTQPQVSLLAPEQTPVV 426
P + P + PP + S PPE + P + + L E++P++
Sbjct: 668 ESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLL 726
Score = 47.0 bits (110), Expect = 7e-05
Identities = 96/433 (22%), Positives = 163/433 (37%), Gaps = 73/433 (16%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63
+ ++++LQ++QQ QLQ Q QQQQ QQ LL P QA
Sbjct: 3254 EHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLS-----APGPAQA-------------- 3294
Query: 64 PQQPLLNLQGTNSASLLNGSMLQRALLL--QQLQGLDQFAMP--PATYDTAGLTMPTATL 119
++L S+ L GS Q +L L + GL Q MP P + P+ +
Sbjct: 3295 -----MSLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAM 3349
Query: 120 GNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGR 179
+ +G+ ++ L P Q + P L Q +G P + M P Q +
Sbjct: 3350 VSNQGHMLSGQHGGQAGLVPQQSSQPVLS--------QKPMGTMPPSMCMKPQQLAM--- 3398
Query: 180 NPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQ-DLPPCP--- 235
Q + ++S P D+ ED DP ++ A + Q + P
Sbjct: 3399 ----QQQLANSFFP---DTDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQGSIGVAPGMN 3451
Query: 236 ---EDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQ 292
+ ++ + P + + + RS+ +P++ P Q + Q
Sbjct: 3452 RQQVSLLAQRLSGGPSSDLQNHVAAGSGQERSAGDPSQPRP----NPPTFAQGVINEADQ 3507
Query: 293 TQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPE 352
Q + L Q L + Q +VL+ Q V +++ + + + ++ +
Sbjct: 3508 RQYEEWL---FHTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKL 3564
Query: 353 HLVL-QQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHT 411
LV QQ ++Q QL Q + QK+ HT E+ Q Q +Q +Q H+
Sbjct: 3565 KLVTEQQSKIQKQLDQVRKQQKE-----HTNLM-----AEYRNKQQQQQQQQQQQQQQHS 3614
Query: 412 QPQVSLLAPEQTP 424
V L+P Q+P
Sbjct: 3615 --AVLALSPSQSP 3625
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/363 (21%), Positives = 119/363 (32%), Gaps = 65/363 (17%)
Query: 103 PPATYDTAGLTMPTATLG---NLRGY---------GMASPG---LAAPSLTPPQLATPN- 146
PPA T + PT G + G+ G SPG L P P Q+ + +
Sbjct: 2117 PPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDP 2176
Query: 147 --------LQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQA---RTSSSTTPNR 195
L+ FP A P P G P P S R Q T+ TP
Sbjct: 2177 FGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRH 2236
Query: 196 KDSSSQTM-----PVEDKSDPPE----GSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPA 246
+ S+ P D PE G +A+EP + P + E +E +
Sbjct: 2237 QPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASS 2296
Query: 247 PE---------PEPCEASELPAKRLRSSE----------EPTEKEPPGQ-LQVKAQPQAR 286
P P + L L++ + E + PG L+ + P A+
Sbjct: 2297 PSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQ 2356
Query: 287 MTVPKQTQTPDLLPEA------LEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 340
P PD+ + + PR QP + + ++ P P + P+
Sbjct: 2357 ALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQ 2416
Query: 341 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQ 400
Q +Q+ +P L + P + P +P Q++ P PP Q
Sbjct: 2417 SQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRP---Q 2473
Query: 401 PPE 403
PPE
Sbjct: 2474 PPE 2476
Score = 37.4 bits (85), Expect = 0.059
Identities = 72/350 (20%), Positives = 121/350 (34%), Gaps = 50/350 (14%)
Query: 204 PVEDKSDPPEGSEEAAEPRMDTPEDQDLP----------PCPEDIAKEKRTPAPEPEPCE 253
P+ + PP ++ A+EPR+ + + P PC IA K PAP
Sbjct: 3093 PLGPEERPPPAAD-ASEPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEPAPAANSLG 3151
Query: 254 ASELPAKRLRSSEEPTEKEPP----GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLP 309
P + + S + P G KA A P TP L + +L
Sbjct: 3152 LGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSGPGGSSLLE 3211
Query: 310 RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEA 369
+F+ + + T P P+ K++ P L + + ++E
Sbjct: 3212 KFE-------LESGALTLPGGPAASGDELDKMESSLVASELP----LLIEDLLEHEKKEL 3260
Query: 370 EPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHV 429
+ ++Q+ Q+ Q Q Q+H + +S P Q PH SL +Q
Sbjct: 3261 QKKQQLSAQLQPAQQQQQQQQQH--SLLSAPGPAQAMSLPHEGSSPSLAGSQQQL----- 3313
Query: 430 CGLEMPPDAVEAGGGMEKTLPEP-VGTQVSMEEIQNESACGLDVGECENRAREMPGVWGA 488
++ G + LP+P + TQ +Q A + + N+ + G G
Sbjct: 3314 --------SLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAM--VSNQGHMLSGQHGG 3363
Query: 489 GGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFF 538
L + Q S S P+ +P S+ P + + A FF
Sbjct: 3364 QAGL---VPQQSSQPVLSQKPMGTMP---PSMCMKPQQLAMQQQLANSFF 3407
Score = 37.0 bits (84), Expect = 0.077
Identities = 74/378 (19%), Positives = 119/378 (31%), Gaps = 57/378 (15%)
Query: 129 SPGLAAPSLTP----PQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQ 184
SP P L+P P L+ + + + L P P ++P P
Sbjct: 807 SPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPEL-----EKPPLS 861
Query: 185 ARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDI---AKE 241
R + + + +P+ P S EP + P + L P PE++
Sbjct: 862 PRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSG 921
Query: 242 KRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQV------KAQPQARMTVPKQTQT 295
+ + +P+ P + P + ++ P P G+L+ + P++ + P
Sbjct: 922 EPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAP----- 976
Query: 296 PDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSP--EH 353
LE + P + + P S P L + Q SP +H
Sbjct: 977 ------ILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQH 1030
Query: 354 LVLQQKQVQPQLQQEAEPQKQVQP--------------QVHTQAQPSVQPQEHPPAQVSV 399
++ Q Q A P P ++H V E P +
Sbjct: 1031 SLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALE--- 1087
Query: 400 QPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGL---EMPPDAVEAGGGMEKTLPEPVGTQ 456
P T P +S AP P + GL P D ++A G PEP T
Sbjct: 1088 --PSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQ----PEPGQTP 1141
Query: 457 VSMEEIQNESACGLDVGE 474
S+ S LD E
Sbjct: 1142 GSLASELKGSPVLLDPEE 1159
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 79.0 bits (193), Expect = 2e-14
Identities = 84/304 (27%), Positives = 119/304 (39%), Gaps = 51/304 (16%)
Query: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
Q QQQ+QQQQQQLQ++ Q QLQQQQ QQQQ Q QQ Q+ P P P QQP
Sbjct: 226 QNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQP-------PMQQP 278
Query: 65 QQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRG 124
Q P S LQ+ Q Q Q PP + P + L
Sbjct: 279 QPP---------PSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVS 329
Query: 125 YGMASPG-----------LAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQ 173
A PG + AP + P +QQ Q Q+ V + SQ
Sbjct: 330 QAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQ--QQTAVQTAQAAQMVAPGVQVSQ 387
Query: 174 FNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPP 233
+L SS +P ++ + Q+MP PP+ S + +P + P
Sbjct: 388 SSLP---------MLSSPSPGQQVQTPQSMP-----PPPQPSPQPGQPSSQPNSNVSSGP 433
Query: 234 CPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQT 293
P + P+P P+P + S + A+ ++ P+ PG L P + M+ +
Sbjct: 434 AP---SPSSFLPSPSPQPSQ-SPVTARTPQNFSVPS----PGPLNTPVNPSSVMSPAGSS 485
Query: 294 QTPD 297
Q +
Sbjct: 486 QAEE 489
Score = 71.6 bits (174), Expect = 3e-12
Identities = 90/335 (26%), Positives = 121/335 (36%), Gaps = 26/335 (7%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQ---------LLQLQQLLQQSPPQAP--LP 52
QQQQQQ QQQQQ Q QQQQ QQQQ Q QQ ++Q QQ LQQ Q +
Sbjct: 163 QQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIK 222
Query: 53 MAVSRGLPPQQPQQPL-----LNLQGTNSASLLNGSMLQRALLLQ---QLQGLDQFAMPP 104
+ QQ QQ L L LQ Q+AL Q Q + Q PP
Sbjct: 223 LHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP 282
Query: 105 ATYDTAGLTMPTATLGNLRGYGMASPGLA--APSLTPPQLATPNLQQFFPQATRQSLLGP 162
+ L T + P +A PS PPQ T L Q L
Sbjct: 283 SQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ 342
Query: 163 PPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDP----PEGSEEA 218
PP+ P PQ Q + ++ T + + V S P P ++
Sbjct: 343 PPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQV 402
Query: 219 AEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQ 278
P+ P Q P + ++ + P P +S LP+ + S+ P P
Sbjct: 403 QTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFS 462
Query: 279 VKAQPQARMTV-PKQTQTPDLLPEALEAQVLPRFQ 312
V + V P +P +A E Q L + +
Sbjct: 463 VPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLK 497
Score = 64.7 bits (156), Expect = 3e-10
Identities = 88/333 (26%), Positives = 135/333 (40%), Gaps = 61/333 (18%)
Query: 246 APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEA 305
AP ++ P +L+ + +++ Q Q + Q QA + +Q Q +A ++
Sbjct: 137 APHSMAVVSTATPQTQLQLQQVALQQQQQQQ-QFQQQQQAALQQQQQQQQQQQF-QAQQS 194
Query: 306 QVLPRFQPRVLQVQA-QVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQ 364
+ +FQ V Q Q Q Q Q Q + Q Q ++Q+Q Q L LQQ+Q Q Q
Sbjct: 195 AMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQ 254
Query: 365 LQQEAEPQK-QVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQT 423
QQ+ + Q Q QP + QP +Q + PP+Q Q +Q H H QP P+Q
Sbjct: 255 QQQQQQQQALQAQPPIQ---QPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQ---PQQP 308
Query: 424 PVVVHVCGLEMPP---------DAVEAGGGMEKTLP-------------EPVGTQVSMEE 461
PV + ++PP A G M T P PV QV ++
Sbjct: 309 PVAQNQPS-QLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQ 367
Query: 462 IQNESACGLDVGECENRAREM--PGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPS-- 517
++A +A +M PGV + SL + S + + + P P+PS
Sbjct: 368 TAVQTA----------QAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQ 417
Query: 518 ---------DSVSSTPAAT-----STPSKQALQ 536
+VSS PA + +PS Q Q
Sbjct: 418 PGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQ 450
Score = 31.6 bits (70), Expect = 3.2
Identities = 27/91 (29%), Positives = 36/91 (39%), Gaps = 12/91 (13%)
Query: 331 PSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQE---------AEPQKQVQPQVHT 381
P + + P T T L LQQ +Q Q QQ+ + Q+Q Q Q
Sbjct: 130 PPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQF 189
Query: 382 QAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQ 412
QAQ S Q+ Q VQ +Q +Q Q
Sbjct: 190 QAQQSAMQQQF---QAVVQQQQQLQQQQQQQ 217
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 75.9 bits (185), Expect = 1e-13
Identities = 121/475 (25%), Positives = 178/475 (37%), Gaps = 62/475 (13%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQ--SPPQAPLP----MAVSR 57
QQQQQQ QQQQQQ QQ QQQQLQ + QQ Q Q Q + Q +P Q P+P S
Sbjct: 265 QQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSG 324
Query: 58 GLPPQQPQQPLLNL---QGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTM 114
L P Q L + QG A L G M Q+ L + + PP Y
Sbjct: 325 ALQPPPAQGSLGTMTANQGWKKAP-LPGPMQQQLQARPSLATVQTPSHPPPPYPFGS--- 380
Query: 115 PTATLGNLRGYGMASPG----------LAAPSLTPPQLATPNLQQFFPQATRQSLLGPPP 164
A+ + M++PG PS P L P+L P ++ S P
Sbjct: 381 QQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSP 440
Query: 165 VGVP-MNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRM 223
P +N +Q + R PQ P S + V+ + PP +P
Sbjct: 441 ASSPTVNQTQQQMGPRPPQNNPLPQGFQQP--VSSPGRNPMVQQGNVPPNFMVMQQQPPN 498
Query: 224 DTPED---------QDLPP-------CPEDI-AKEKRTPAPEPEPCEASELPA-KRLRSS 265
P+ + LPP P + + T A P A +L A + ++ +
Sbjct: 499 QGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHA 558
Query: 266 EEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQ 325
P Q+QV P M ++ + +P Q + +Q Q Q
Sbjct: 559 GGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVP--QVNLSNMQGQPQQG 616
Query: 326 TQPRIPSTDTQVQPKLQKQAQTQ--TSPEH-LVLQQKQVQPQLQQEAEPQKQVQPQVHTQ 382
++ Q+ P + Q Q +P++ ++L + Q+ PQ Q P Q
Sbjct: 617 PPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQ-------N 669
Query: 383 AQPSVQPQEHPPAQVSVQPPEQTHEQPHTQ---PQVSLLAPEQTPVVVHVCGLEM 434
PS Q P +S Q P+ PH Q PQ +L +Q P++ + +M
Sbjct: 670 LGPSPQRMTPPKQMLSQQGPQMM--APHNQMMGPQGQVLL-QQNPMIEQIMTNQM 721
Score = 49.3 bits (116), Expect = 1e-05
Identities = 100/448 (22%), Positives = 155/448 (34%), Gaps = 94/448 (20%)
Query: 2 FSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQ-APLPMAVSRG-- 58
F+ Q Q + Q+ + +Q +Q + Q L QQ P +P + +G
Sbjct: 728 FNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQV 787
Query: 59 LPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTAT 118
L P P + G + + N L + + +Q + +PP G +A+
Sbjct: 788 LRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNM--VPPHVQAMQG---NSAS 842
Query: 119 LGNLRGYGMASPGLAAPSLTPPQLATPNLQQF-------FPQATRQSLLGPPPVGV---P 168
+ G+GM S P PN Q FP +L P V +
Sbjct: 843 GNHFSGHGM--------SFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSD 894
Query: 169 MNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDP---PEGSEEAAEPRMDT 225
++ F ++ + A P RK +SQ +D + P P G EEA +P +
Sbjct: 895 ISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQ----QDLNTPDTRPAGLEEADQPPLPG 950
Query: 226 PE----DQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKA 281
+ D P PE R P +P E + P ++ PP +Q A
Sbjct: 951 EQGINLDNSGPKLPEF---SNRPPGYPSQPVE------------QRPLQQMPPQLMQHVA 995
Query: 282 QPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKL 341
P QP Q Q Q+ Q QP PS QP+
Sbjct: 996 PPP---------------------------QPPQQQPQPQLPQQQQPPPPS-----QPQS 1023
Query: 342 QKQAQTQTSPEHLVLQQKQVQ----PQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQV 397
Q+Q Q Q +++ Q+ + P Q P+ + P +Q P +Q P V
Sbjct: 1024 QQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPD--SQRMP-MQQSGSVPVMV 1080
Query: 398 SVQPPEQTHEQPHTQPQVSLLAPEQTPV 425
S+Q P P Q + P TP+
Sbjct: 1081 SLQGPASVPPSPDKQ---RMPMPVNTPL 1105
Score = 48.9 bits (115), Expect = 2e-05
Identities = 76/291 (26%), Positives = 112/291 (38%), Gaps = 34/291 (11%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGL-PPQ 62
QQ Q QL QQQQ Q Q QQQQ QQQ ++ L ++QQ P LP VS+ + PP+
Sbjct: 1003 QQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMML--MMQQDPKSVRLP--VSQNVHPPR 1058
Query: 63 QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTAT-LGN 121
P LN +GS+ ++ LQG A P + D + MP T LG+
Sbjct: 1059 GP----LNPDSQRMPMQQSGSV----PVMVSLQGP---ASVPPSPDKQRMPMPVNTPLGS 1107
Query: 122 LRGYGMASPGLAAPSLTP-PQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
+ PS +P ++A+ P+A+ G VP P+
Sbjct: 1108 NSRKMVYQESPQNPSSSPLAEMAS------LPEAS-----GSEAPSVPGGPNNMPSHVVL 1156
Query: 181 PQKQ-ARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIA 239
PQ Q T P+ ++ P + + S P + P P P +
Sbjct: 1157 PQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRAS 1216
Query: 240 KE---KRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARM 287
+TP P E SE+ R + PP Q+ + P+ +
Sbjct: 1217 PRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPP-QINIPLPPRPNL 1266
Score = 45.1 bits (105), Expect = 3e-04
Identities = 63/299 (21%), Positives = 94/299 (31%), Gaps = 40/299 (13%)
Query: 140 PQLATPNLQQFFPQATRQSLLGPP-----PVGV--PMNPSQFNLSGRNPQKQARTSSSTT 192
P L+ ++QQ Q+ L PP PV V MNP+ F + Q+Q +
Sbjct: 219 PLLSGLHIQQ---QSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQ 275
Query: 193 PNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTP------- 245
++ Q + + + P+ P +PP + P
Sbjct: 276 QQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSL 335
Query: 246 -----------APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQ 294
AP P P + L + + P+ PP + QA P+ +
Sbjct: 336 GTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSN 395
Query: 295 TPDL-LPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEH 353
P+ Q P P LQ QP + + P +Q +SP
Sbjct: 396 PGQFTAPQMKSLQGGPSRVPTPLQ---------QPHLTNKSPASSPSSFQQGSPASSPTV 446
Query: 354 LVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPP--AQVSVQPPEQTHEQPH 410
QQ+ Q PQ QP P VQ PP + QPP Q + H
Sbjct: 447 NQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLH 505
Score = 42.0 bits (97), Expect = 0.002
Identities = 51/208 (24%), Positives = 78/208 (37%), Gaps = 47/208 (22%)
Query: 222 RMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPG-QLQVK 280
RM+ P +PP +++ P P PE + PA S + + G +Q +
Sbjct: 175 RMNNPATVMIPP-GGNVSSSMMAPGPNPELQPRTPRPA----SQSDAMDPLLSGLHIQQQ 229
Query: 281 AQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 340
+ P + P P + V Q+ P+ Q+Q +
Sbjct: 230 SHPSGSLAPPHHPMQP-------------------VSVNRQMN-------PANFPQLQQQ 263
Query: 341 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQP-SVQPQEHPPAQVSV 399
Q+Q Q Q QQ+Q Q Q QQ+ + Q + PQ H Q QP ++PQ P QV V
Sbjct: 264 QQQQQQQQ--------QQQQQQQQQQQQQQLQAR-PPQQHQQQQPQGIRPQFTAPTQVPV 314
Query: 400 QP-----PEQTHEQPHTQPQVSLLAPEQ 422
P P + P Q + + Q
Sbjct: 315 PPGWNQLPSGALQPPPAQGSLGTMTANQ 342
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 73.9 bits (180), Expect = 6e-13
Identities = 122/480 (25%), Positives = 172/480 (35%), Gaps = 131/480 (27%)
Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQ---------------------------- 32
+ QQQQQQ QQQQQQ QQ QQQQ QQQQ QQ
Sbjct: 2716 LLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKL 2775
Query: 33 --QQLLQLQQLLQQSPPQAPLPMA------------VSRGLPPQQPQQPLLNLQGTNSAS 78
+ L+++Q+ Q PPQ P P A V PPQQ L + +
Sbjct: 2776 TPEHLIKMQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGA 2835
Query: 79 LLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLT-MPTATLGNLRGYGMASPGLAAPSL 137
LL G+ + A A LT +PT+ L +P A +L
Sbjct: 2836 LLTGTTV-------------------ANLQVARLTRVPTSQLQAQGQMQTQAPQPAQVAL 2876
Query: 138 TPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKD 197
P + + P A S P +PMN + +++ PQK A
Sbjct: 2877 AKPPVVS------VPAAVVSS---PGVTTLPMNVAGISVAIGQPQKAA------------ 2915
Query: 198 SSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASEL 257
G A+P Q L + ++++ A +P+ +
Sbjct: 2916 ----------------GQTVVAQP----VHMQQLLKLKQQAVQQQK--AIQPQAAQGPAA 2953
Query: 258 PAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQ 317
+++ + + T PG AQ + +T L +AQ L Q Q
Sbjct: 2954 VQQKITAQQITT----PG-----AQQKVAYAAQPALKTQFLTTPISQAQKLAGAQ----Q 3000
Query: 318 VQAQVQSQTQPRIPSTDTQVQPKLQ-KQAQTQTSPEHLVL-------QQKQVQPQLQQEA 369
VQ Q+Q P++ T V Q A Q SP+ + L QQ Q+ P + A
Sbjct: 3001 VQTQIQVAKLPQVVQQQTPVASIQQVASASQQASPQTVALTQATAAGQQVQMIPAVTATA 3060
Query: 370 E--PQKQVQPQVHTQAQPSVQPQEHP-PAQV--SVQPPEQTHEQPHTQPQVSLLAPEQTP 424
+ QK +Q QV T A +Q P PAQV S P Q + P V L P + P
Sbjct: 3061 QVVQQKLIQQQVVTTASAPLQTPGAPNPAQVPASSDSPSQQPKLQMRVPAVRLKTPTKPP 3120
Score = 65.1 bits (157), Expect = 3e-10
Identities = 103/451 (22%), Positives = 149/451 (33%), Gaps = 69/451 (15%)
Query: 16 QLQQLQQQQLQQQQ--LQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQG 73
Q+ L+ +++ +++ L QQ Q + Q PPQ P PPQQP PL Q
Sbjct: 2476 QVASLRAERIAKEKKALADQQKAQQPAVAQPPPPQPQPPP------PPQQPPPPLPQPQA 2529
Query: 74 TNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLA 133
GS Q Q Q P P T G G G
Sbjct: 2530 A-------GSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAITTG---GSAAVLAGTI 2579
Query: 134 APSLTPPQLAT--------PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQA 185
S+T + T N P AT QS+ + P+ P G + Q
Sbjct: 2580 KTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSI--NKRLASPVAPGALTTPGGSAPAQV 2637
Query: 186 RTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTP 245
+ P S + P +G +L P + R+
Sbjct: 2638 -VHTQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTASAVVTTNLTP----VQTPARSL 2692
Query: 246 APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEA 305
P+ +LP K + P Q+ Q Q + +Q Q
Sbjct: 2693 VPQVSQATGVQLPGKTI----------TPAHFQLLRQQQQQQQQQQQQQ----------- 2731
Query: 306 QVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQL 365
Q + Q + Q Q Q + +Q ++P Q Q Q +A + +PEHL+ QKQ
Sbjct: 2732 QQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMP 2791
Query: 366 QQEAEPQKQ---VQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQ 422
Q PQ Q QP Q Q S PQ+ P +V T P+ L
Sbjct: 2792 PQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTV-----------TAPRPGALLTGT 2840
Query: 423 TPVVVHVCGL-EMPPDAVEAGGGMEKTLPEP 452
T + V L +P ++A G M+ P+P
Sbjct: 2841 TVANLQVARLTRVPTSQLQAQGQMQTQAPQP 2871
Score = 38.9 bits (89), Expect = 0.020
Identities = 35/120 (29%), Positives = 49/120 (40%), Gaps = 28/120 (23%)
Query: 228 DQDLPPCP------EDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKA 281
D+ LPP E IAKEK+ A + + +++P +PP
Sbjct: 2469 DKPLPPIQVASLRAERIAKEKKALADQ--------------QKAQQPAVAQPP------- 2507
Query: 282 QPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKL 341
PQ + P Q Q P LP+ A P P +Q Q Q Q QTQP+ + QP +
Sbjct: 2508 PPQPQPPPPPQ-QPPPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAI 2566
Score = 36.2 bits (82), Expect = 0.13
Identities = 54/247 (21%), Positives = 93/247 (37%), Gaps = 42/247 (17%)
Query: 157 QSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQT-MPVEDKSDPPEGS 215
Q L+ G+P P L+G+ +Q S+ P + +S T +P PP G
Sbjct: 506 QQLMPTAQGGMPPTPQAAQLAGQRQSQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPAGV 565
Query: 216 EEAA---------EPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSE 266
AA +P++ + Q P K ++ P P P +S+LP + ++
Sbjct: 566 PTAALSSALQFAQQPQVVEAQTQLQIP-----VKTQQPNVPIPAP-PSSQLPIPPSQPAQ 619
Query: 267 EPTEKEPPGQLQVKAQ-----PQ----ARMTVPKQTQTPDLLPEALEAQVLP-------- 309
PG++QV+A PQ R+ V P LP + + + P
Sbjct: 620 LALHVPTPGKVQVQASQLSSLPQMVASTRLPVDPAPPCPRPLPTSSTSSLAPVSGSGPGP 679
Query: 310 ---------RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360
R + + V S+T + S T+ Q Q +Q S + + +Q
Sbjct: 680 SPARSSPVNRPSSATNKALSPVTSRTPGVVASAPTKPQSPAQNATSSQDSSQDTLTEQIT 739
Query: 361 VQPQLQQ 367
++ Q+ Q
Sbjct: 740 LENQVHQ 746
Score = 34.3 bits (77), Expect = 0.50
Identities = 64/313 (20%), Positives = 102/313 (32%), Gaps = 51/313 (16%)
Query: 296 PDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLV 355
P + +L A+ + + + + L Q + Q + P Q P Q+ P+
Sbjct: 2473 PPIQVASLRAERIAK-EKKALADQQKAQQPAVAQPPPPQPQPPPPPQQPPPPLPQPQAAG 2531
Query: 356 LQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQV 415
Q P +Q + +PQ Q QPQ VQ P + T
Sbjct: 2532 SQPPAGPPAVQPQPQPQPQTQPQ-------------------PVQAPAKAQPAITTGGSA 2572
Query: 416 SLLAPEQTPVVVHVCGLEMPPDAVEAG--------------GGMEKTLPEPVGTQV---- 457
++LA + V G MP AV + K L PV
Sbjct: 2573 AVLA---GTIKTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSINKRLASPVAPGALTTP 2629
Query: 458 ---SMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVP 514
+ ++ + VG ++ + G VT + +S A T LTPV
Sbjct: 2630 GGSAPAQVVHTQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTAS---AVVTTNLTPVQ 2686
Query: 515 RPSDSV---SSTPAATSTPSKQALQFFCYICKASCSSQQEFQDHMSEPQHQQRLGEIQHM 571
P+ S+ S P K + + QQ+ Q + Q QQ+ + Q
Sbjct: 2687 TPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQ-QQQQQQQQQQQQQQQQQQQQQQQQQ 2745
Query: 572 SQACLLSLLPVPR 584
Q S + VP+
Sbjct: 2746 QQTTTTSQVQVPQ 2758
Score = 33.9 bits (76), Expect = 0.65
Identities = 48/183 (26%), Positives = 72/183 (39%), Gaps = 17/183 (9%)
Query: 17 LQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP--PQQPQQPLLNLQGT 74
LQ QQ Q+ + Q Q Q ++ QQ P P+P S LP P QP Q L++ T
Sbjct: 574 LQFAQQPQVVEAQTQLQIPVKTQQ------PNVPIPAPPSSQLPIPPSQPAQLALHVP-T 626
Query: 75 NSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGL-TMPTATLGNLRGYGMA-SPGL 132
+ S L L Q+ + + PA L T T++L + G G SP
Sbjct: 627 PGKVQVQASQLSS---LPQMVASTRLPVDPAPPCPRPLPTSSTSSLAPVSGSGPGPSPAR 683
Query: 133 AAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTT 192
++P P L P +R + P +P+Q S ++ + T T
Sbjct: 684 SSPVNRPSSATNKALS---PVTSRTPGVVASAPTKPQSPAQNATSSQDSSQDTLTEQITL 740
Query: 193 PNR 195
N+
Sbjct: 741 ENQ 743
Score = 33.5 bits (75), Expect = 0.85
Identities = 44/174 (25%), Positives = 60/174 (34%), Gaps = 18/174 (10%)
Query: 125 YGMASPG--LAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGV-PMNPSQFNLSGRNP 181
YG G +A PS PP+ A P PQ L G PP+ NP +
Sbjct: 1432 YGQKPEGRTVAFPSTHPPRTAAPTTASAAPQG---PLRGRPPIATFSANPEAKAAAAPFQ 1488
Query: 182 QKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKE 241
QA S+ SS+ P + + +A+ P P+ P P A +
Sbjct: 1489 TSQASASAPRHQPASASSTAASPAHPAKLRAQTTAQASTPGQPPPQ----PQAPSHAAGQ 1544
Query: 242 KRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQT 295
P P +A RL S E QL PQ+R+ P+ T
Sbjct: 1545 SALPQRLVLPSQAQ----ARLPSG----EVVKIAQLASITGPQSRVAQPETPVT 1590
Score = 32.3 bits (72), Expect = 1.9
Identities = 76/291 (26%), Positives = 102/291 (35%), Gaps = 59/291 (20%)
Query: 313 PRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHL--------VLQQKQVQPQ 364
P+ Q+ Q QSQ Q PST VQ P L L Q
Sbjct: 520 PQAAQLAGQRQSQQQYD-PSTGPPVQNAASLHTPLPQLPGRLPPAGVPTAALSSALQFAQ 578
Query: 365 LQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHE---QPHTQPQVSLLAPE 421
Q E Q Q+Q V TQ QP+V P PP+ PP Q + T +V + A +
Sbjct: 579 QPQVVEAQTQLQIPVKTQ-QPNV-PIPAPPSSQLPIPPSQPAQLALHVPTPGKVQVQASQ 636
Query: 422 QTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRARE 481
+ + V +P D P P+ T S + S G
Sbjct: 637 LSSLPQMVASTRLPVDPA-------PPCPRPLPTS-STSSLAPVSGSG------------ 676
Query: 482 MPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYI 541
PG A S V S+ ++A S V R V+S P +P++ A
Sbjct: 677 -PGPSPARSS-PVNRPSSATNKALSPV----TSRTPGVVASAPTKPQSPAQNA------- 723
Query: 542 CKASCSSQQEFQDHMSEP-----QHQQRLGEIQH---MSQACLLSLLPVPR 584
SSQ QD ++E Q QR+ E++ SQ L L PR
Sbjct: 724 ----TSSQDSSQDTLTEQITLENQVHQRIAELRKAGLWSQRRLPKLQEAPR 770
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 69.7 bits (169), Expect = 1e-11
Identities = 83/313 (26%), Positives = 127/313 (40%), Gaps = 59/313 (18%)
Query: 153 QATRQSLLGPPPVGVPMNPSQFNLSGRNP----QKQARTSSSTTPNRKDSSSQTMPVEDK 208
Q T Q L P V V P Q + P Q+ T +TT +++ T+
Sbjct: 2174 QTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTT-A 2232
Query: 209 SDPPEGSEEAAEPRMDTPEDQDLPPC------PEDIAKEKRTPAPEPEPCEASELPAK-- 260
+ E + P+M +D+ LPP P + + P+ +P+P + PA+
Sbjct: 2233 AGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPE 2292
Query: 261 ----------RLRSSEEPTEKEPPG------QLQVKAQPQA--------RMTVPKQTQ-- 294
SS P+E +P Q+ ++QPQ+ R+ P QT+
Sbjct: 2293 VQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIR 2352
Query: 295 --TPDLLPEALEAQVLPR------FQPRV-LQVQAQVQSQTQPRIPSTDTQVQPKLQKQA 345
TP L ++QV QP LQ+ +Q Q Q+QP++ S+ +
Sbjct: 2353 PSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQ 2412
Query: 346 QTQTSPEHLVLQQKQVQ------PQLQQEAEPQKQVQPQV--HTQAQPSVQPQE---HPP 394
T +SP LQ +Q Q PQLQQ+ + Q+Q QV QAQ S PQ+ P
Sbjct: 2413 VTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLP 2472
Query: 395 AQVSVQPPEQTHE 407
Q+ QTH+
Sbjct: 2473 IQIQQSSAVQTHQ 2485
Score = 65.9 bits (159), Expect = 2e-10
Identities = 49/157 (31%), Positives = 73/157 (46%), Gaps = 11/157 (7%)
Query: 282 QPQARMTVPKQTQTPDLLPEALEAQVLP-RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 340
Q Q++++ Q LP A + V P QP+ Q AQ Q QTQP+ P+ QP+
Sbjct: 2238 QRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPA-----QPE 2292
Query: 341 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQ--KQVQPQVHTQAQPSVQPQEHPPAQVS 398
+Q Q + QT + QP Q ++PQ Q QPQ + Q Q V+ Q P+Q
Sbjct: 2293 VQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQS--PSQTR 2350
Query: 399 VQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMP 435
++P + P Q QV + P+ H L++P
Sbjct: 2351 IRPSTPSQLSPGQQSQVQTTTSQPIPIQPHT-SLQIP 2386
Score = 60.5 bits (145), Expect = 6e-09
Identities = 104/438 (23%), Positives = 173/438 (39%), Gaps = 48/438 (10%)
Query: 3 SQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQ 62
S Q + QQ Q +L Q QL Q Q L + Q Q+ Q L LP
Sbjct: 2133 SASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPG- 2191
Query: 63 QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNL 122
P Q L+ A++ NG++ QR L P AT T T T
Sbjct: 2192 -PGQQLMQ------AAMPNGTV-QRFLFT-----------PLATTATTASTTTTTVSTTA 2232
Query: 123 RGYGMASPGLAAP--------SLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQF 174
G G +P +L P Q ++ + PQ T Q P P P +P+Q
Sbjct: 2233 AGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQ-TAQPSAQPQPQTQPQSPAQP 2291
Query: 175 NLSGRNPQKQARTSSSTTPNRKD---SSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDL 231
+ + + T SS P+ + S V +S P + + R+ +P +
Sbjct: 2292 EVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRI 2351
Query: 232 -PPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVP 290
P P ++ +++ + + + +P + S + P++ +P Q QV++ Q +
Sbjct: 2352 RPSTPSQLSPGQQS---QVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQ 2408
Query: 291 KQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTS 350
Q P + Q+ + QP+V+ V Q+Q Q Q +Q+Q ++ Q Q Q S
Sbjct: 2409 TLNQVTVSSPSRPQLQI-QQPQPQVIAVP-QLQQQVQVL-----SQIQSQVVAQIQAQQS 2461
Query: 351 --PEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQ 408
P+ + LQ + Q+QQ + Q V T SVQ Q Q+ Q ++ +Q
Sbjct: 2462 GVPQQIKLQ---LPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQ 2518
Query: 409 PHTQPQVSLLAPEQTPVV 426
+ + +L A Q+ ++
Sbjct: 2519 IEIKREHTLQASNQSEII 2536
Score = 32.7 bits (73), Expect = 1.4
Identities = 90/469 (19%), Positives = 153/469 (32%), Gaps = 62/469 (13%)
Query: 164 PVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRM 223
P+GVP P + PQ++ SS+ P R ++ QT PV ++ E E E R
Sbjct: 1844 PIGVPETPKETP----TPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRA 1899
Query: 224 DTPE-DQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQ 282
+++ E AK++ ++ P S+ P +K +
Sbjct: 1900 FAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVT 1959
Query: 283 PQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQA-----QVQSQTQPRIPS----- 332
+M + + +P + F V Q Q+ QVQ + IPS
Sbjct: 1960 TGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTS 2019
Query: 333 --TDTQVQPKL-------QKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQ--------- 374
T T QP+ T+ V+ Q++P + P +Q
Sbjct: 2020 QQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIR 2079
Query: 375 --VQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGL 432
V Q Q Q P +V P P Q SL + T +
Sbjct: 2080 TPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTP---GQKSLTSATSTSNI--QSSA 2134
Query: 433 EMPPDAVEAGGGMEKTLPEPV-------GTQVSMEEIQNESACGLDVGECENRAREMPGV 485
PP + G ++ T+ + G Q IQ + G G+ + + + +
Sbjct: 2135 SQPPRPQQ--GQVKLTMAQLTQLTQGHGGNQGLTVVIQGQ---GQTTGQLQLIPQGVTVL 2189
Query: 486 WGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKAS 545
G G L + + + F PL + + ++T + T+ + + Q
Sbjct: 2190 PGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQ------SKL 2243
Query: 546 CSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEP 594
Q QD P +G + Q S P P +T+ + P
Sbjct: 2244 SPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQP----QTQPQSP 2288
Score = 31.6 bits (70), Expect = 3.2
Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 9/53 (16%)
Query: 653 HKDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEE 705
+ D E + E+++ ++E+ +GD EE +D ED+EE E+EE+
Sbjct: 126 YDDHESEEEEEEEDMVSEEEEEE---------DGDAEETQDSEDDEEDEMEED 169
Score = 30.0 bits (66), Expect = 9.4
Identities = 17/60 (28%), Positives = 26/60 (43%)
Query: 232 PPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPK 291
P P A E+ PAP P P + P LRS + + Q + P+ R++ P+
Sbjct: 9 PKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPR 68
>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
Length = 3703
Score = 67.0 bits (162), Expect = 7e-11
Identities = 87/322 (27%), Positives = 121/322 (37%), Gaps = 41/322 (12%)
Query: 130 PGLAAPSL---TPPQLAT----PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQ 182
PGL +PSL TP A PNL P T S G P G+P PS +LS P
Sbjct: 3127 PGLNSPSLPGFTPSNTALTSPKPNLMGL-PSTTVPSP-GLPTSGLPNKPSSASLSSPTPA 3184
Query: 183 KQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEK 242
+ P ++ Q P + PP ++ P++ + Q + KEK
Sbjct: 3185 QATMAMGPQQPPQQQQQQQ-QPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEK 3243
Query: 243 R---------TPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQT 293
P P+ E EA A + S+ PT + Q++A A + P
Sbjct: 3244 EKAHKGKGEPLPVPKKEKGEAPTATAATI-SAPLPTMEYAVDPAQLQALQAALTSDPTAL 3302
Query: 294 QTPDLLPEALEAQVLPRFQPRVL-QVQAQVQS-QTQPRIPSTDTQVQPKLQKQAQTQTSP 351
T LP +P F P Q+ +QS QP QA SP
Sbjct: 3303 LTSQFLP-----YFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSPALSQALMGLSP 3357
Query: 352 EHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQP---------- 401
L+ Q +Q Q LQ+ Q+Q Q Q+ Q Q VQ Q+ +Q V P
Sbjct: 3358 GSLLQQYQQYQQSLQEAI--QQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPA 3415
Query: 402 --PEQTHEQPHTQPQVSLLAPE 421
+ EQ +T +VS L P+
Sbjct: 3416 KESPKPEEQKNTPREVSPLLPK 3437
Score = 56.6 bits (135), Expect = 9e-08
Identities = 111/446 (24%), Positives = 152/446 (34%), Gaps = 61/446 (13%)
Query: 3 SQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQ 62
S+QQQQQ QQQQQQ QQ QQQ Q Q Q LQQ LQQ
Sbjct: 1721 SRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQ------------------ 1762
Query: 63 QPQQPLLNLQGTNSASLLNGSMLQRALL-LQQLQG-LDQFAMPPATYDTAGLTMPTATLG 120
Q L+ Q N L + M LL LQQ Q L F +P A + T G
Sbjct: 1763 --QAALIQSQLFNPTLLPHFPMTTETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSG 1820
Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
L G PGL Q+ + QQ PQ + L + PSQ +
Sbjct: 1821 ALTLTG-TGPGLLEDLKAQVQVPQQSHQQILPQQQQNQLSIAQSHSALLQPSQ------H 1873
Query: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
P+K+ + K+ SQ + D EG E P+ + LP + K
Sbjct: 1874 PEKK----NKLVIKEKEKESQR-----ERDSAEGGEGNTGPK------ETLPDALKAKEK 1918
Query: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300
++ P EP A R + E G V + + V K+ D
Sbjct: 1919 KELAPGGGSEPSMLPPRIASDARGNATKALLENFGFELVIQYNENKQKVQKKNGKTDQGE 1978
Query: 301 --EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQ 358
E LE + +L +++ + Q P + K + + P
Sbjct: 1979 NLEKLECDSCGKLFSNILILKSHQEHVHQNYFPFKQLERFAKQYRDHYDKLYP------- 2031
Query: 359 KQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQP---PEQTHEQPHTQPQV 415
++PQ + P P A P QP P S P P QP + P
Sbjct: 2032 --LRPQTPEPPPPPPPPPPPPLPAAPP--QPASTPAIPASAPPITSPTIAPAQP-SVPLT 2086
Query: 416 SLLAPEQTPVVVHVCGLEMPPDAVEA 441
L P + P+ + MP + A
Sbjct: 2087 QLSMPMELPIFSPLMMQTMPLQTLPA 2112
Score = 47.4 bits (111), Expect = 6e-05
Identities = 46/218 (21%), Positives = 83/218 (38%), Gaps = 25/218 (11%)
Query: 539 CYICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRR 598
C +C+ + + FQ H +H Q+ + H+ + + + + P
Sbjct: 986 CKLCRYNTQLKANFQLHCKTDKHVQKYQLVAHIKEGGKANEWRLKCVAIGN-----PVHL 1040
Query: 599 WCNTCQLY---------------YMGDLIQHRRTQDHK--IAKQSLRPFCTVCNRYFKTP 641
CN C Y + L ++ Q H+ + +S C +CN K
Sbjct: 1041 KCNACDYYTNSLEKLRLHTVNSRHEASLKLYKHLQQHESGVEGESCYYHCVLCNYSTKAK 1100
Query: 642 RKFVEHVKSQGHK--DKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEE-EDDEDEE 698
++HV+S H+ + ++L+ L+K + +DED C D EE ED E
Sbjct: 1101 LNLIQHVRSMKHQRSESLRKLQRLQKGLPEEDEDLGQIFTIRRCPSTDPEEAIEDVEGPS 1160
Query: 699 EIEVEEELCKQVRSRDISREEWKGSETYSPNTAYGVDF 736
E + E + + S + + T SP T+ + F
Sbjct: 1161 ETAADPEELAKDQEGGASSSQAEKELTDSPATSKRISF 1198
Score = 43.1 bits (100), Expect = 0.001
Identities = 24/49 (48%), Positives = 29/49 (59%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLP 52
QQ QQ Q Q+ +QQ QQ+QLQQQQ Q+ Q Q + PP AP P
Sbjct: 3362 QQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSP 3410
Score = 42.0 bits (97), Expect = 0.002
Identities = 75/259 (28%), Positives = 101/259 (38%), Gaps = 70/259 (27%)
Query: 3 SQQQQQQLQQQQQQLQQLQQQQLQQQQLQ--QQQLLQLQQL--LQQSPPQAP---LPMAV 55
S Q Q ++Q Q +LQQQ+ +Q+ QQ+L QL L L Q PPQAP P+
Sbjct: 2437 SAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQ 2496
Query: 56 SRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMP 115
S P Q PL L + L N +PP
Sbjct: 2497 SSPSPSQLSHLPLKPLHTSTPQQLAN--------------------LPP----------- 2525
Query: 116 TATLGNLRGYGMASPGLAAPSLTPPQ-------LATPNLQQFFPQATRQSLLGPPPVGVP 168
L Y LA PS Q L+ N Q PQ +SL P + P
Sbjct: 2526 -----QLIPYQCDQCKLAFPSFEHWQEHQQLHFLSAQN-QFIHPQFLDRSLDMPFMLFDP 2579
Query: 169 MNP---SQFNLSGRNPQKQARTSSSTTPNRKDSSSQTM--PVEDKSDPPEGSEEAA---- 219
NP SQ LSG PQ A SS+T+P+ S+ T+ +E+K+ G ++
Sbjct: 2580 SNPLLASQL-LSGAIPQIPA--SSATSPSTPTSTMNTLKRKLEEKASASPGENDSGTGGE 2636
Query: 220 EPRMD-------TPEDQDL 231
EP+ D TPE ++
Sbjct: 2637 EPQRDKRLRTTITPEQLEI 2655
Score = 40.4 bits (93), Expect = 0.007
Identities = 22/55 (40%), Positives = 30/55 (54%)
Query: 10 LQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
L QQ QQ QQ Q+ +QQQQ +Q Q Q Q++ QQ P + P+ P + P
Sbjct: 3360 LLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDP 3414
Score = 39.7 bits (91), Expect = 0.012
Identities = 80/367 (21%), Positives = 137/367 (37%), Gaps = 58/367 (15%)
Query: 316 LQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQ--- 372
LQ+ A+ + + +PKL + Q P +Q Q +P+LQQ+ +P+
Sbjct: 2407 LQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQ--PNQTQEKQGQPKPELQQQEQPEQKT 2464
Query: 373 ---KQVQPQVHT-----QAQPSVQPQEHPPAQVSVQPPEQTH-----EQPHTQPQVSLLA 419
+Q PQ+ + Q P P + P Q S P + +H T Q++ L
Sbjct: 2465 NTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLP 2524
Query: 420 PEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRA 479
P+ P C L P E Q+ QN+ + +R+
Sbjct: 2525 PQLIPYQCDQCKLAFP--------SFEHWQEH---QQLHFLSAQNQ----FIHPQFLDRS 2569
Query: 480 REMP-GVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFF 538
+MP ++ L + L S + +P S + STP +T K+ L+
Sbjct: 2570 LDMPFMLFDPSNPLLASQLLSG--------AIPQIPASSATSPSTPTSTMNTLKRKLEE- 2620
Query: 539 CYICKASCS-SQQEFQDHMSEPQHQQRL------GEIQHMSQACLLSLLPVPRDVLETED 591
KAS S + + EPQ +RL +++ + Q LL P R +L+
Sbjct: 2621 ----KASASPGENDSGTGGEEPQRDKRLRTTITPEQLEILYQKYLLDSNPT-RKMLDHIA 2675
Query: 592 EEPPPRRWCNTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQ 651
E ++ Q+++ + R+ Q + C C FK H++S+
Sbjct: 2676 HEVGLKK--RVVQVWFQNTRARERKGQFRAVGPAQAHRRCPFCRALFKAKTALEAHIRSR 2733
Query: 652 GHKDKAK 658
H +AK
Sbjct: 2734 -HWHEAK 2739
Score = 39.3 bits (90), Expect = 0.015
Identities = 58/270 (21%), Positives = 96/270 (35%), Gaps = 27/270 (10%)
Query: 4 QQQQQQLQQQQQQLQ--------------QLQQQQLQQQQLQQQQLLQLQQLLQQSPPQA 49
Q QQQ QQQQ Q+Q QL QQ QQ++ + + ++ ++ + +
Sbjct: 3194 QPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGE- 3252
Query: 50 PLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDT 109
PLP +P ++ + T SA L ++ A+ QLQ L T
Sbjct: 3253 PLP------VPKKEKGEAPTATAATISAPL---PTMEYAVDPAQLQALQAALTSDPTALL 3303
Query: 110 AGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPM 169
+P G Y PG P L + P A Q+L+G P +
Sbjct: 3304 TSQFLPYFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSP-ALSQALMGLSPGSLLQ 3362
Query: 170 NPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQ 229
Q+ S + +Q + ++ Q PP +P ++P+ +
Sbjct: 3363 QYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPKPE 3422
Query: 230 DLPPCPEDIAK--EKRTPAPEPEPCEASEL 257
+ P +++ K PE E A L
Sbjct: 3423 EQKNTPREVSPLLPKLPEEPEAESKSADSL 3452
Score = 37.0 bits (84), Expect = 0.077
Identities = 46/202 (22%), Positives = 74/202 (36%), Gaps = 31/202 (15%)
Query: 177 SGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLP--PC 234
+G K A S+ ++ Q P + + PE ++ P+ P+ LP P
Sbjct: 2425 AGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPE--QKTNTPQQKLPQLVSLPSLPQ 2482
Query: 235 PEDIAKEKRTPAPE--PEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVP-- 290
P A + P P+ P P + S LP K L +S P QL Q ++ P
Sbjct: 2483 PPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQCKLAFPSF 2542
Query: 291 ---------------KQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRI----- 330
Q P L +L+ + F P + +Q+ S P+I
Sbjct: 2543 EHWQEHQQLHFLSAQNQFIHPQFLDRSLDMPFM-LFDPSNPLLASQLLSGAIPQIPASSA 2601
Query: 331 --PSTDTQVQPKLQKQAQTQTS 350
PST T L+++ + + S
Sbjct: 2602 TSPSTPTSTMNTLKRKLEEKAS 2623
Score = 33.9 bits (76), Expect = 0.65
Identities = 18/50 (36%), Positives = 27/50 (54%)
Query: 339 PKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQ 388
P K+A + + + +Q+Q Q Q QQ+ + Q+Q Q Q QAQ VQ
Sbjct: 1704 PSEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQ 1753
Score = 33.5 bits (75), Expect = 0.85
Identities = 15/34 (44%), Positives = 23/34 (67%)
Query: 685 EGDEEEEEDDEDEEEIEVEEELCKQVRSRDISRE 718
E + EEEE++E+EEE E E+E CK + ++ E
Sbjct: 469 EEEAEEEEEEEEEEEEEEEDEGCKGLFPSELDEE 502
Score = 32.0 bits (71), Expect = 2.5
Identities = 21/73 (28%), Positives = 32/73 (43%), Gaps = 6/73 (8%)
Query: 318 VQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQP 377
+ A + S ++P+ + +Q Q Q QQ+Q Q Q QQ+A+ Q Q
Sbjct: 1697 IGANIASPSEPKEANRKKLADMIASRQQQQQQQ------QQQQQQQQQQQQAQTLAQAQA 1750
Query: 378 QVHTQAQPSVQPQ 390
QV Q +Q Q
Sbjct: 1751 QVQAHLQQELQQQ 1763
Score = 30.8 bits (68), Expect = 5.5
Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 9/54 (16%)
Query: 661 KSLEKEIAGQDEDHFITVDAVGCF---------EGDEEEEEDDEDEEEIEVEEE 705
KS E + +G E V CF E +EEEEE++ +EEE E EEE
Sbjct: 429 KSSEGKDSGAAEGEKQEVGDGDCFSEKVEPAEEEAEEEEEEEEAEEEEEEEEEE 482
Score = 30.4 bits (67), Expect = 7.2
Identities = 14/21 (66%), Positives = 17/21 (80%)
Query: 685 EGDEEEEEDDEDEEEIEVEEE 705
E +EEEEE +E+EEE E EEE
Sbjct: 464 EEEEEEEEAEEEEEEEEEEEE 484
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 65.9 bits (159), Expect = 2e-10
Identities = 49/157 (31%), Positives = 73/157 (46%), Gaps = 11/157 (7%)
Query: 282 QPQARMTVPKQTQTPDLLPEALEAQVLP-RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 340
Q Q++++ Q LP A + V P QP+ Q AQ Q QTQP+ P+ QP+
Sbjct: 2364 QRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPA-----QPE 2418
Query: 341 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQ--KQVQPQVHTQAQPSVQPQEHPPAQVS 398
+Q Q + QT + QP Q ++PQ Q QPQ + Q Q V+ Q P+Q
Sbjct: 2419 VQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQS--PSQTR 2476
Query: 399 VQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMP 435
++P + P Q QV + P+ H L++P
Sbjct: 2477 IRPSTPSQLSPGQQSQVQTTTSQPIPIQPHT-SLQIP 2512
Score = 62.4 bits (150), Expect = 2e-09
Identities = 69/272 (25%), Positives = 104/272 (38%), Gaps = 38/272 (13%)
Query: 153 QATRQSLLGPPPVGVPMNPSQFNLSGRNP----QKQARTSSSTTPNRKDSSSQTMPVEDK 208
Q T Q L P V V P Q + P Q+ T +TT +++ T+
Sbjct: 2300 QTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTT-A 2358
Query: 209 SDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEP 268
+ E + P+M +D+ LPP P EA A+ +
Sbjct: 2359 AGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVG----------PAEAQPQTAQPSAQPQPQ 2408
Query: 269 TEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVL---QVQAQVQSQ 325
T+ + P Q +V+ QP+ V QT +P + +P+V Q Q+ VQ Q
Sbjct: 2409 TQPQSPAQPEVQTQPE----VQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQ 2464
Query: 326 TQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQP 385
+ R+ S Q +++ +Q SP QQ QVQ Q Q Q+ +Q QP
Sbjct: 2465 SPVRVQSPS---QTRIRPSTPSQLSPG----QQSQVQTTTSQPIPIQPHTSLQIPSQGQP 2517
Query: 386 SVQPQ---------EHPPAQVSVQPPEQTHEQ 408
QPQ EH + S+ P E+ Q
Sbjct: 2518 QSQPQVVMKHNAVIEHLKQKKSMTPAEREENQ 2549
Score = 43.1 bits (100), Expect = 0.001
Identities = 40/143 (27%), Positives = 50/143 (34%), Gaps = 8/143 (5%)
Query: 275 GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTD 334
GQLQ+ Q + P Q L+ A+ + RF L A S T + +T
Sbjct: 2303 GQLQLIPQGVTVLPGPGQ----QLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTA 2358
Query: 335 T----QVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQ 390
Q Q KL Q Q Q V P Q Q QPQ TQ Q QP+
Sbjct: 2359 AGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPE 2418
Query: 391 EHPPAQVSVQPPEQTHEQPHTQP 413
+V Q +H QP
Sbjct: 2419 VQTQPEVQTQTTVSSHVPSEAQP 2441
Score = 32.7 bits (73), Expect = 1.4
Identities = 90/469 (19%), Positives = 153/469 (32%), Gaps = 62/469 (13%)
Query: 164 PVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRM 223
P+GVP P + PQ++ SS+ P R ++ QT PV ++ E E E R
Sbjct: 1970 PIGVPETPKETP----TPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRA 2025
Query: 224 DTPE-DQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQ 282
+++ E AK++ ++ P S+ P +K +
Sbjct: 2026 FAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVT 2085
Query: 283 PQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQA-----QVQSQTQPRIPS----- 332
+M + + +P + F V Q Q+ QVQ + IPS
Sbjct: 2086 TGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTS 2145
Query: 333 --TDTQVQPKL-------QKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQ--------- 374
T T QP+ T+ V+ Q++P + P +Q
Sbjct: 2146 QQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIR 2205
Query: 375 --VQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGL 432
V Q Q Q P +V P P Q SL + T +
Sbjct: 2206 TPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTP---GQKSLTSATSTSNI--QSSA 2260
Query: 433 EMPPDAVEAGGGMEKTLPEPV-------GTQVSMEEIQNESACGLDVGECENRAREMPGV 485
PP + G ++ T+ + G Q IQ + G G+ + + + +
Sbjct: 2261 SQPPRPQQ--GQVKLTMAQLTQLTQGHGGNQGLTVVIQGQ---GQTTGQLQLIPQGVTVL 2315
Query: 486 WGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKAS 545
G G L + + + F PL + + ++T + T+ + + Q
Sbjct: 2316 PGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQ------SKL 2369
Query: 546 CSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEP 594
Q QD P +G + Q S P P +T+ + P
Sbjct: 2370 SPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQP----QTQPQSP 2414
Score = 31.6 bits (70), Expect = 3.2
Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 9/53 (16%)
Query: 653 HKDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEE 705
+ D E + E+++ ++E+ +GD EE +D ED+EE E+EE+
Sbjct: 126 YDDHESEEEEEEEDMVSEEEEEE---------DGDAEETQDSEDDEEDEMEED 169
Score = 30.0 bits (66), Expect = 9.4
Identities = 17/60 (28%), Positives = 26/60 (43%)
Query: 232 PPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPK 291
P P A E+ PAP P P + P LRS + + Q + P+ R++ P+
Sbjct: 9 PKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPR 68
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 65.5 bits (158), Expect = 2e-10
Identities = 53/116 (45%), Positives = 58/116 (50%), Gaps = 12/116 (10%)
Query: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
QQQQQ QQQQQQ QQ QQQQ QQQQ QQQQ Q QQ QQ P + QQ
Sbjct: 152 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGK-----QAKEQQQQQQQ 206
Query: 65 QQPLLNLQGTNSASLLNGSMLQRA--LLLQQLQGL-----DQFAMPPATYDTAGLT 113
QQ L Q LL LQ+ LL Q QGL Q A+P + AGL+
Sbjct: 207 QQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLS 262
Score = 55.1 bits (131), Expect = 3e-07
Identities = 53/159 (33%), Positives = 71/159 (44%), Gaps = 20/159 (12%)
Query: 265 SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVL-PRFQPRVLQVQAQVQ 323
S + ++K+ P Q+ V A MT Q TP + + L+ QVL P+ +LQ Q V
Sbjct: 75 SPKSSDKQRPLQVPVSV---AMMT--PQVITPQQMQQILQQQVLSPQQLQALLQQQQAVM 129
Query: 324 SQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQA 383
Q Q Q+Q +KQ E L LQ Q Q Q QQ+ + Q+Q Q Q Q
Sbjct: 130 LQQQ--------QLQEFYKKQQ------EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQ 175
Query: 384 QPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQ 422
Q Q Q+ Q P +Q EQ Q Q LA +Q
Sbjct: 176 QQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ 214
Score = 49.3 bits (116), Expect = 1e-05
Identities = 51/159 (32%), Positives = 64/159 (40%), Gaps = 15/159 (9%)
Query: 5 QQQQQLQQQQQQLQQL---QQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP 61
QQQQ + QQQQLQ+ QQ+QL Q LQQQQ Q QQ QQ Q +
Sbjct: 123 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 182
Query: 62 QQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGN 121
QQ QQ G + Q+ L QQL Q L +
Sbjct: 183 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLL-------S 235
Query: 122 LRGYGMAS--PGLAA---PSLTPPQLATPNLQQFFPQAT 155
L+ G+ S PG AA SL L+ +QQ + + T
Sbjct: 236 LQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVT 274
Score = 43.9 bits (102), Expect = 6e-04
Identities = 37/136 (27%), Positives = 54/136 (39%), Gaps = 3/136 (2%)
Query: 278 QVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQV---QAQVQSQTQPRIPSTD 334
QV Q + + +Q +P L L+ Q Q + LQ + Q Q Q
Sbjct: 97 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQ 156
Query: 335 TQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPP 394
Q Q + Q+Q Q Q + QQ+Q Q Q QQ+ P KQ + Q Q Q +
Sbjct: 157 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLV 216
Query: 395 AQVSVQPPEQTHEQPH 410
Q + +Q +Q H
Sbjct: 217 FQQQLLQMQQLQQQQH 232
Score = 36.2 bits (82), Expect = 0.13
Identities = 33/126 (26%), Positives = 53/126 (42%), Gaps = 12/126 (9%)
Query: 301 EALEA--QVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQ 358
+AL+A Q+L + Q L+ Q ++P + + P++ Q Q + VL
Sbjct: 56 QALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSP 115
Query: 359 KQVQPQLQQE----------AEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQ 408
+Q+Q LQQ+ E K+ Q Q+H Q Q Q+ Q Q +Q +Q
Sbjct: 116 QQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQ 175
Query: 409 PHTQPQ 414
Q Q
Sbjct: 176 QQQQQQ 181
Score = 33.5 bits (75), Expect = 0.85
Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 6/86 (6%)
Query: 12 QQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAV--SRGLPPQQPQQPLL 69
QQQQ LQ +Q LQQQ L + +Q P Q P+ +A+ + + PQQ QQ +L
Sbjct: 53 QQQQALQAARQLLLQQQT---SGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQ-IL 108
Query: 70 NLQGTNSASLLNGSMLQRALLLQQLQ 95
Q + L Q+A++LQQ Q
Sbjct: 109 QQQVLSPQQLQALLQQQQAVMLQQQQ 134
Score = 31.2 bits (69), Expect = 4.2
Identities = 26/68 (38%), Positives = 32/68 (47%), Gaps = 11/68 (16%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLL-----QLQQLLQQSPPQAPLPMAVSRG 58
QQ QQ LQQQ QQLQ LQQQQ + QLQ+ ++ Q L + +
Sbjct: 102 QQMQQILQQQVLSPQQLQAL------LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 155
Query: 59 LPPQQPQQ 66
QQ QQ
Sbjct: 156 QQQQQQQQ 163
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 65.5 bits (158), Expect = 2e-10
Identities = 53/116 (45%), Positives = 58/116 (50%), Gaps = 12/116 (10%)
Query: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
QQQQQ QQQQQQ QQ QQQQ QQQQ QQQQ Q QQ QQ P + QQ
Sbjct: 60 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGK-----QAKEQQQQQQQ 114
Query: 65 QQPLLNLQGTNSASLLNGSMLQRA--LLLQQLQGL-----DQFAMPPATYDTAGLT 113
QQ L Q LL LQ+ LL Q QGL Q A+P + AGL+
Sbjct: 115 QQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLS 170
Score = 52.0 bits (123), Expect = 2e-06
Identities = 45/132 (34%), Positives = 58/132 (43%), Gaps = 15/132 (11%)
Query: 292 QTQTPDLLPEALEAQVL-PRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTS 350
Q TP + + L+ QVL P+ +LQ Q V Q Q Q+Q +KQ
Sbjct: 5 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQ--------QLQEFYKKQQ----- 51
Query: 351 PEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPH 410
E L LQ Q Q Q QQ+ + Q+Q Q Q Q Q Q Q+ Q P +Q EQ
Sbjct: 52 -EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQ 110
Query: 411 TQPQVSLLAPEQ 422
Q Q LA +Q
Sbjct: 111 QQQQQQQLAAQQ 122
Score = 49.3 bits (116), Expect = 1e-05
Identities = 51/159 (32%), Positives = 64/159 (40%), Gaps = 15/159 (9%)
Query: 5 QQQQQLQQQQQQLQQL---QQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP 61
QQQQ + QQQQLQ+ QQ+QL Q LQQQQ Q QQ QQ Q +
Sbjct: 31 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 90
Query: 62 QQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGN 121
QQ QQ G + Q+ L QQL Q L +
Sbjct: 91 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLL-------S 143
Query: 122 LRGYGMAS--PGLAA---PSLTPPQLATPNLQQFFPQAT 155
L+ G+ S PG AA SL L+ +QQ + + T
Sbjct: 144 LQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVT 182
Score = 46.6 bits (109), Expect = 1e-04
Identities = 55/241 (22%), Positives = 94/241 (39%), Gaps = 34/241 (14%)
Query: 278 QVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQV 337
QV Q + + +Q +P L L+ Q Q + LQ + + Q ++ Q
Sbjct: 5 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQ---EFYKKQQEQLHLQLLQQ 61
Query: 338 QPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQV 397
Q + Q+Q Q Q + QQ+Q Q Q QQ+ + Q+Q P + Q Q Q+ A
Sbjct: 62 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ 121
Query: 398 SVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQV 457
+ +Q + Q Q LL+ ++ ++ +PP + LP
Sbjct: 122 QLVFQQQLLQMQQLQQQQHLLSLQRQGLI------SIPPG--------QAALP------- 160
Query: 458 SMEEIQNESACGLDVGECENRAREMPGVWG------AGGSLKVTILQSSDSRAFSTVPLT 511
+Q+ GL E + +E+ GV G L +T SS + + +T +
Sbjct: 161 ----VQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKAS 216
Query: 512 P 512
P
Sbjct: 217 P 217
Score = 38.9 bits (89), Expect = 0.020
Identities = 53/188 (28%), Positives = 74/188 (39%), Gaps = 23/188 (12%)
Query: 274 PGQLQVKAQPQARMTVPKQT-------QTPDLLPEALEAQVLPRFQPRVLQVQAQV-QSQ 325
P QLQ Q Q + + +Q Q L + L+ Q + Q + Q Q Q Q Q
Sbjct: 23 PQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQ 82
Query: 326 TQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQP 385
Q Q Q + Q+Q Q Q P +Q+Q Q Q QQ A Q Q Q+ Q
Sbjct: 83 QQ-------QQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQ- 134
Query: 386 SVQPQEH-----PPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVE 440
+Q Q+H +S+ PP Q + PQ L E + V G+ D
Sbjct: 135 -LQQQQHLLSLQRQGLISI-PPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGI 192
Query: 441 AGGGMEKT 448
GG++ T
Sbjct: 193 KHGGLDLT 200
Score = 31.2 bits (69), Expect = 4.2
Identities = 26/68 (38%), Positives = 32/68 (47%), Gaps = 11/68 (16%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLL-----QLQQLLQQSPPQAPLPMAVSRG 58
QQ QQ LQQQ QQLQ LQQQQ + QLQ+ ++ Q L + +
Sbjct: 10 QQMQQILQQQVLSPQQLQAL------LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 63
Query: 59 LPPQQPQQ 66
QQ QQ
Sbjct: 64 QQQQQQQQ 71
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 65.5 bits (158), Expect = 2e-10
Identities = 53/116 (45%), Positives = 58/116 (50%), Gaps = 12/116 (10%)
Query: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
QQQQQ QQQQQQ QQ QQQQ QQQQ QQQQ Q QQ QQ P + QQ
Sbjct: 177 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGK-----QAKEQQQQQQQ 231
Query: 65 QQPLLNLQGTNSASLLNGSMLQRA--LLLQQLQGL-----DQFAMPPATYDTAGLT 113
QQ L Q LL LQ+ LL Q QGL Q A+P + AGL+
Sbjct: 232 QQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLS 287
Score = 52.8 bits (125), Expect = 1e-06
Identities = 47/143 (32%), Positives = 62/143 (43%), Gaps = 15/143 (10%)
Query: 281 AQPQARMTVPKQTQTPDLLPEALEAQVL-PRFQPRVLQVQAQVQSQTQPRIPSTDTQVQP 339
A P + + Q TP + + L+ QVL P+ +LQ Q V Q Q Q+Q
Sbjct: 111 AVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQ--------QLQE 162
Query: 340 KLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSV 399
+KQ E L LQ Q Q Q QQ+ + Q+Q Q Q Q Q Q Q+ Q
Sbjct: 163 FYKKQQ------EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 216
Query: 400 QPPEQTHEQPHTQPQVSLLAPEQ 422
P +Q EQ Q Q LA +Q
Sbjct: 217 HPGKQAKEQQQQQQQQQQLAAQQ 239
Score = 49.3 bits (116), Expect = 1e-05
Identities = 51/159 (32%), Positives = 64/159 (40%), Gaps = 15/159 (9%)
Query: 5 QQQQQLQQQQQQLQQL---QQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP 61
QQQQ + QQQQLQ+ QQ+QL Q LQQQQ Q QQ QQ Q +
Sbjct: 148 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 207
Query: 62 QQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGN 121
QQ QQ G + Q+ L QQL Q L +
Sbjct: 208 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLL-------S 260
Query: 122 LRGYGMAS--PGLAA---PSLTPPQLATPNLQQFFPQAT 155
L+ G+ S PG AA SL L+ +QQ + + T
Sbjct: 261 LQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVT 299
Score = 46.6 bits (109), Expect = 1e-04
Identities = 55/241 (22%), Positives = 94/241 (39%), Gaps = 34/241 (14%)
Query: 278 QVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQV 337
QV Q + + +Q +P L L+ Q Q + LQ + + Q ++ Q
Sbjct: 122 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQ---EFYKKQQEQLHLQLLQQ 178
Query: 338 QPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQV 397
Q + Q+Q Q Q + QQ+Q Q Q QQ+ + Q+Q P + Q Q Q+ A
Sbjct: 179 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ 238
Query: 398 SVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQV 457
+ +Q + Q Q LL+ ++ ++ +PP + LP
Sbjct: 239 QLVFQQQLLQMQQLQQQQHLLSLQRQGLI------SIPPG--------QAALP------- 277
Query: 458 SMEEIQNESACGLDVGECENRAREMPGVWG------AGGSLKVTILQSSDSRAFSTVPLT 511
+Q+ GL E + +E+ GV G L +T SS + + +T +
Sbjct: 278 ----VQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKAS 333
Query: 512 P 512
P
Sbjct: 334 P 334
Score = 38.9 bits (89), Expect = 0.020
Identities = 53/188 (28%), Positives = 74/188 (39%), Gaps = 23/188 (12%)
Query: 274 PGQLQVKAQPQARMTVPKQT-------QTPDLLPEALEAQVLPRFQPRVLQVQAQV-QSQ 325
P QLQ Q Q + + +Q Q L + L+ Q + Q + Q Q Q Q Q
Sbjct: 140 PQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQ 199
Query: 326 TQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQP 385
Q Q Q + Q+Q Q Q P +Q+Q Q Q QQ A Q Q Q+ Q
Sbjct: 200 QQ-------QQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQ- 251
Query: 386 SVQPQEH-----PPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVE 440
+Q Q+H +S+ PP Q + PQ L E + V G+ D
Sbjct: 252 -LQQQQHLLSLQRQGLISI-PPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGI 309
Query: 441 AGGGMEKT 448
GG++ T
Sbjct: 310 KHGGLDLT 317
Score = 31.2 bits (69), Expect = 4.2
Identities = 26/68 (38%), Positives = 32/68 (47%), Gaps = 11/68 (16%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLL-----QLQQLLQQSPPQAPLPMAVSRG 58
QQ QQ LQQQ QQLQ LQQQQ + QLQ+ ++ Q L + +
Sbjct: 127 QQMQQILQQQVLSPQQLQAL------LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 180
Query: 59 LPPQQPQQ 66
QQ QQ
Sbjct: 181 QQQQQQQQ 188
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 65.5 bits (158), Expect = 2e-10
Identities = 67/296 (22%), Positives = 114/296 (38%), Gaps = 27/296 (9%)
Query: 162 PPPVGVPMNPSQFNLSGRNPQKQAR----TSSSTTPNRKDSSSQTMPVEDKSDPPEGSEE 217
PP V + Q L P+++AR +++ TP + + P+ ++ E S E
Sbjct: 414 PPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAE 473
Query: 218 -----AAEPRMD-TPEDQDLPPCPEDIAKEK----RTPAPEPEPCEASELPAKRLRSSEE 267
A EP D TP + P E A+E ++P E E + + L + E
Sbjct: 474 IQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEA 533
Query: 268 PTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQA------- 320
P ++ P ++ + P + Q+P ++E L P + A
Sbjct: 534 PADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAI 593
Query: 321 QVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVH 380
Q+ + T+ +VQP ++A + P +VQP +EA + Q P
Sbjct: 594 QLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEE 653
Query: 381 TQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPP 436
A+ P E PA+V P E+ +V L E+TP+ + + PP
Sbjct: 654 APAEVQPPPAEEAPAEVQPPPAEE------APAEVQSLPAEETPIEETLAAVHSPP 703
Score = 48.9 bits (115), Expect = 2e-05
Identities = 70/325 (21%), Positives = 119/325 (36%), Gaps = 58/325 (17%)
Query: 196 KDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDL-----PPCPEDIAKEK-------- 242
+ S+Q P+E + P EG+ E A +++ P ++ P PE+ +E+
Sbjct: 385 RSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLST 444
Query: 243 --RTPA---------PEPEPCEASELPAK-RLRSSEEPTEKEPPGQLQ---------VKA 281
TPA P P+ A E A+ +L ++ EP E P + + +A
Sbjct: 445 AMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEA 504
Query: 282 QPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTD--TQVQP 339
+ + + ++T + + E Q+L + + A+ QS + + +VQ
Sbjct: 505 HAEVQSPLAEETTAEE---ASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQS 561
Query: 340 KLQKQAQTQTSPEHLVLQQKQVQPQLQQEA---------------EPQKQVQPQVHTQAQ 384
K + +P L LQ + +EA E +VQP +A
Sbjct: 562 PSAKGVSIEEAP--LELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAP 619
Query: 385 PSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPE--QTPVVVHVCGLEMPPDAVEAG 442
VQP A VQPP QP + AP Q P PP A EA
Sbjct: 620 AEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAP 679
Query: 443 GGMEKTLPEPVGTQVSMEEIQNESA 467
++ E + ++ + + A
Sbjct: 680 AEVQSLPAEETPIEETLAAVHSPPA 704
Score = 46.6 bits (109), Expect = 1e-04
Identities = 47/209 (22%), Positives = 73/209 (34%), Gaps = 24/209 (11%)
Query: 192 TPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRM--------------DTPEDQDLPPCPED 237
+P+ K S + P+E PP G E AE + P + PP E+
Sbjct: 561 SPSAKGVSIEEAPLE--LQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPA-EE 617
Query: 238 IAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPG--QLQVKAQPQARMTVPKQTQT 295
E + P E P E PA+ E P E +PP + + QP P + Q
Sbjct: 618 APAEVQPPPAEEAPAEVQPPPAE-----EAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQP 672
Query: 296 PDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLV 355
P E Q LP + + + A V S +P+ + V T +
Sbjct: 673 PPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIG 732
Query: 356 LQQKQVQPQLQQEAEPQKQVQPQVHTQAQ 384
+V P ++ + + V T+ Q
Sbjct: 733 EASAEVSPPPSEQTPEDEALVENVSTEFQ 761
Score = 45.4 bits (106), Expect = 2e-04
Identities = 91/450 (20%), Positives = 160/450 (35%), Gaps = 102/450 (22%)
Query: 177 SGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPP-----------------EGS--EE 217
+ +P+ Q T+S+ +K+ S + E K PP EGS ++
Sbjct: 192 ASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKK 251
Query: 218 AAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASEL-------------------- 257
A ++ P + P + E+ T EP P E + +
Sbjct: 252 VASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAE 311
Query: 258 --------PAKRLRSSEEPTEKEPPG-------QLQVKAQPQARMTVPKQTQTPDLLPEA 302
PA+ E P E +PP +L + P + P + ++LP
Sbjct: 312 NSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPP 371
Query: 303 LE----AQVL-----PRFQPRVLQVQ------------AQVQSQTQPRIPSTDTQVQPKL 341
E ++L P Q ++VQ A+V+ P + T VQP L
Sbjct: 372 AEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVE---PPTVEETLADVQPLL 428
Query: 342 QKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQ---------PQEH 392
++A + + E L L P + E Q + P+ T + S + P +
Sbjct: 429 PEEAPREEARE-LQLSTAMETPAEEAPTEFQSPL-PKETTAEEASAEIQLLAATEPPADE 486
Query: 393 PPAQVSVQPPEQTH-EQPHTQPQVSL----LAPEQTPVVVHVCGLEMPPDAVEAGGGMEK 447
PA+ E+T E+ H + Q L A E + + + +E P D E +
Sbjct: 487 TPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPAD--ETPAEAQS 544
Query: 448 TLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG--VWGAGGSLKVTILQSSDSRAF 505
L E + + E+Q+ SA G+ + E + G S + +L ++++ A
Sbjct: 545 PLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASA- 603
Query: 506 STVPLTPVPRPSDSVSS---TPAATSTPSK 532
P P P++ + P A P++
Sbjct: 604 EEAPAEVQPPPAEEAPAEVQPPPAEEAPAE 633
Score = 42.0 bits (97), Expect = 0.002
Identities = 58/256 (22%), Positives = 107/256 (41%), Gaps = 28/256 (10%)
Query: 230 DLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTV 289
++PP E + KE++T E E S + +S E+ + + G++ P+ +
Sbjct: 144 NIPPV-EKVDKEQQTYFSESEIVVISRPDSSSTKSKEDALKHKSSGKIFASEHPEFQ--- 199
Query: 290 PKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQT 349
P ++ + + + + V + + + + +P Q ++K A +
Sbjct: 200 PATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVV--QEGSAVKKVASAEI 257
Query: 350 SPEHLVLQQKQVQPQLQQEAEPQKQVQP--QVHTQAQPSVQPQEHPPAQ---------VS 398
P ++QP L +EA + + +P + H Q QPS +E P A+ V
Sbjct: 258 EPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPST--EETPDAEAATAVAENSVK 315
Query: 399 VQPPEQTHEQPHTQPQVSLLAP--EQTPVVVHVCGLEMPPDAVEAGG--GMEKTLPEPVG 454
VQPP E P + + P E++P V + + +PP A E+ + LP P
Sbjct: 316 VQPP-PAEEAPLVEFPAEIQPPSAEESPSVELLAEI-LPPSAEESPSEEPPAEILPPPAE 373
Query: 455 TQVSME---EIQNESA 467
S+E EI++ SA
Sbjct: 374 KSPSVELLGEIRSPSA 389
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 65.5 bits (158), Expect = 2e-10
Identities = 114/456 (25%), Positives = 159/456 (34%), Gaps = 63/456 (13%)
Query: 104 PATYDTAGL-TMPTATLGNLRGYGMASPGLAAPS---LTPPQ-LATPNLQQFFPQA---- 154
PAT G T P AT + +G P AP+ +TPP TP L P +
Sbjct: 1301 PATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGP 1360
Query: 155 -TRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDP-- 211
T S GP P PS P R + +P +S +P+ K P
Sbjct: 1361 TTPSSKEGPTPPAA--TPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT 1418
Query: 212 PEGSEEAAEPRMDTPEDQDLPP---CPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEP 268
P E AA TP DL P P + K T AP+ P S L + P
Sbjct: 1419 PVTREGAA-----TPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPP 1473
Query: 269 TEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQP-RVLQVQAQVQSQTQ 327
+ KEPP QV A + PK+ P + A LP P +V A S+
Sbjct: 1474 SPKEPPAPKQV-----ATSSSPKKAPA---TPAPMGAPTLPAVIPSSPKEVPATPSSRRD 1525
Query: 328 PRIPS-------TDTQVQPK--LQKQAQTQTSPEH---LVLQQKQVQPQLQQEAEPQKQV 375
P P+ T + PK L A T SP+ + ++ +EA V
Sbjct: 1526 PIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAV 1585
Query: 376 QPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMP 435
P + A PS + PPA S P E T P V+ +PE+ P G
Sbjct: 1586 TPSTYKGA-PSPKELLIPPAVTSPSPKEAP-----TPPAVTPPSPEKGPATPAPKGTPTS 1639
Query: 436 PDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVT 495
P + T P V ++ Q ++ +P G +V
Sbjct: 1640 PPVTPSSLKDSPTSPASVTCKMGATVPQ--------------ASKGLPAKKGPTALKEVL 1685
Query: 496 ILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPS 531
+ + +S T P P+ S +++P PS
Sbjct: 1686 VAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPS 1721
Score = 52.4 bits (124), Expect = 2e-06
Identities = 93/402 (23%), Positives = 144/402 (35%), Gaps = 46/402 (11%)
Query: 33 QQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQ 92
++LL + SP +AP P AV+ P + P P +GT ++ + S L+
Sbjct: 1597 KELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAP--KGTPTSPPVTPSSLK------ 1648
Query: 93 QLQGLDQFAMPPATYDTAGLTMPTATLG--NLRGYGMASPGLAAPSLTPPQLATPNLQQF 150
D P + G T+P A+ G +G L AP+ + T ++
Sbjct: 1649 -----DSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKG 1703
Query: 151 FPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSD 210
PQ + S PP + +PS N G + P +KDSS +T +D S
Sbjct: 1704 -PQTKKSSATSPP---ICPDPSAKN--GSKGPLSTVAPAPLLPVQKDSS-KTAKGKDASH 1756
Query: 211 PPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTE 270
P+G E + TP A EK P PE A+ P L + P
Sbjct: 1757 SPKGPLAPPESKASTPLTA--------AAFEKVLPKPESASVSAAPSPPVSLPLAPSPVP 1808
Query: 271 KEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQS--QTQP 328
PP Q + + P + P + P A E ++LP P + QS P
Sbjct: 1809 TLPPKQQFLPSSPGLVLESPSKPLAP-----ADEDELLPLIPPEPISGGVPFQSVLVNMP 1863
Query: 329 RIPSTDTQVQPKLQKQAQTQTSP-EHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSV 387
S V KQ T+ + + P+L+++ Q Q Q +
Sbjct: 1864 TPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQ---QAQLAAAA 1920
Query: 388 QPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHV 429
+ E P V +Q+ + + +S L Q V V
Sbjct: 1921 EIDEEP-----VSKAKQSRSEKKARKAMSKLGLRQVTGVTRV 1957
Score = 47.8 bits (112), Expect = 4e-05
Identities = 58/251 (23%), Positives = 79/251 (31%), Gaps = 30/251 (11%)
Query: 45 SPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPP 104
SP PLP P P L + +G + L G+ A +G P
Sbjct: 1046 SPAATPLPKGA-----PTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKG------GP 1094
Query: 105 ATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPP 164
AT G MP A G+A TPP P P + + L PPP
Sbjct: 1095 ATPSPKGAPMPPAATPPSPKGGLA---------TPPHKGAPTTPAATPPSPKGGLATPPP 1145
Query: 165 VGVPMNPSQFNLSGRN-----PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAA 219
G P P+ S + P K A T+ + TP T + P + +
Sbjct: 1146 KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP 1205
Query: 220 EPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQV 279
+ + TP + P P + P P A PA + P+ K P
Sbjct: 1206 KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA-----ATPPSPKGGPATPPP 1260
Query: 280 KAQPQARMTVP 290
K P P
Sbjct: 1261 KGAPTPPAATP 1271
Score = 45.8 bits (107), Expect = 2e-04
Identities = 97/453 (21%), Positives = 150/453 (33%), Gaps = 40/453 (8%)
Query: 113 TMPTATLGNLRGYGMASP----GLAAPSLTPPQ----LATPNLQ------QFFPQATRQS 158
T P AT + +G G+A+P P+ TPP LATP+ + P + +
Sbjct: 1150 TTPAATPPSPKG-GLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1208
Query: 159 LLGPPPVGVPMNPSQFNLSGRN-----PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPE 213
L P P G P P+ S + K A T+ + TP T P + PP
Sbjct: 1209 LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPA 1268
Query: 214 GSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEP 273
+ + + + TP + P P + P+P+ P + A ++ P+ K
Sbjct: 1269 ATPPSLKGGLATPPHKGAPN-PAVVT----PPSPKGGPATSPPKGAPTPPAATPPSPKGS 1323
Query: 274 PGQLQVKAQP-QARMTVPKQTQTPDL---LPEALEAQVLPRFQPRVLQVQAQVQSQTQPR 329
PG K P +T P TP L P + P + A + P
Sbjct: 1324 PGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPA 1383
Query: 330 IPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQP---QLQQEAEPQK-QVQPQVHTQAQP 385
+ + P + TSP + L K+ + A P K + P T
Sbjct: 1384 MTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSL 1443
Query: 386 SVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGM 445
P P P + + T P V+ +P++ P V P A M
Sbjct: 1444 KKAPATSAP---KGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPM 1500
Query: 446 -EKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSL---KVTILQSSD 501
TLP + + S +++ P +L +T+
Sbjct: 1501 GAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKK 1560
Query: 502 SRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQA 534
+ A T P S SS PA T + K A
Sbjct: 1561 TPAIPTPKEAPATPSSKEASSPPAVTPSTYKGA 1593
Score = 34.3 bits (77), Expect = 0.50
Identities = 73/334 (21%), Positives = 100/334 (29%), Gaps = 67/334 (20%)
Query: 162 PPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPP-----EGSE 216
P P+GV ++P + R P K+ T + SS PVE P +GS+
Sbjct: 794 PSPLGVSVSPQ----TKRPPTKKGSAGPDTPIG--NLSSPVSPVEASFLPENSLSFQGSK 847
Query: 217 EA-AEPRMDTPEDQDLPPCPEDIAK---------EKRTPAPE----PEPCEASELPAKR- 261
++ A TP P P + K TP P P P E PA +
Sbjct: 848 DSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQ 907
Query: 262 -----LRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVL 316
+ SS + P + A P PK TP P A P+ P
Sbjct: 908 APALSMTSSSPKKARATPAPKGIPASPS-----PKGAPTP---PAATPPS--PKGGP--- 954
Query: 317 QVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQ---QEAEPQK 373
+ P+ T P K SP+ P + P+
Sbjct: 955 -------ATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG 1007
Query: 374 QVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPH-------------TQPQVSLLAP 420
P T P P P + + PP T P T P +L +P
Sbjct: 1008 APTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP 1067
Query: 421 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVG 454
+ P + G PP A P P G
Sbjct: 1068 KGGPATPSLKGAPTPPAATPPSPKGGPATPSPKG 1101
Score = 31.2 bits (69), Expect = 4.2
Identities = 61/286 (21%), Positives = 86/286 (30%), Gaps = 27/286 (9%)
Query: 167 VPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSS--SQTMPVEDKSD--PPEGSEEAAEPR 222
+P N F S +P A T S T P+ K + S P+ K PP+ + +
Sbjct: 836 LPENSLSFQGSKDSP---ATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVN 892
Query: 223 MDTPEDQDLPPCPEDIA----------KEKRTPAPEPEPCEASELPAKRLRSSEEPTEKE 272
+ P++ P P+ K + TPAP+ P S A ++ P+ K
Sbjct: 893 LPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKG 952
Query: 273 PPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPS 332
P K P P + P A P P + S P
Sbjct: 953 GPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPP 1012
Query: 333 TDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEH 392
T PK A P+ A P + P PS P+
Sbjct: 1013 AVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS--PKGG 1070
Query: 393 PPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDA 438
P P T P + +P+ P G MPP A
Sbjct: 1071 PATPSLKGAP--------TPPAATPPSPKGGPATPSPKGAPMPPAA 1108
Score = 31.2 bits (69), Expect = 4.2
Identities = 68/322 (21%), Positives = 96/322 (29%), Gaps = 40/322 (12%)
Query: 115 PTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQF 174
PT ++ NL G A P+ P Q ++ P+ R + P P G+P +PS
Sbjct: 886 PTPSVVNLP---FPKEGPATPA--PKQAPALSMTSSSPKKARAT---PAPKGIPASPSP- 936
Query: 175 NLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPC 234
K A T + TP T + PP + + + TP + P
Sbjct: 937 --------KGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTP 988
Query: 235 PEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQ 294
P + P P A PA T P G P+ T P
Sbjct: 989 PAATPPSPKGGPATPSPKGAPTPPA--------VTPPSPKGSPAATPFPKGASTPP--AA 1038
Query: 295 TPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPS-----TDTQVQPKLQKQAQTQT 349
TP + A LP+ P + P PS T P K
Sbjct: 1039 TPPSPKGSPAATPLPKGAP-TTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATP 1097
Query: 350 SPEHLVLQQKQVQPQLQQE-AEPQKQVQPQVHTQAQPS------VQPQEHPPAQVSVQPP 402
SP+ + P + A P + P PS P + P + PP
Sbjct: 1098 SPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1157
Query: 403 EQTHEQPHTQPQVSLLAPEQTP 424
P+ + P TP
Sbjct: 1158 SPKGGLATPPPKGAPTTPAATP 1179
Score = 30.4 bits (67), Expect = 7.2
Identities = 36/167 (21%), Positives = 57/167 (34%), Gaps = 9/167 (5%)
Query: 113 TMPTATLGNLRGYGMASPGLAAPSLTP-PQLATPNLQQFFPQATRQSLLGPPPVGVPMNP 171
T P AT + +G P +P P P ATP + P PP P +P
Sbjct: 964 TPPAATPPSPKG----GPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSP 1019
Query: 172 SQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDL 231
+ P+ + ++T P+ K S + T + P + + + TP +
Sbjct: 1020 KGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA 1079
Query: 232 PPCPEDIAKEKR----TPAPEPEPCEASELPAKRLRSSEEPTEKEPP 274
P P + TP+P+ P + P P K P
Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAP 1126
>gi|62953127 polyhomeotic 1-like [Homo sapiens]
Length = 1004
Score = 64.3 bits (155), Expect = 4e-10
Identities = 122/497 (24%), Positives = 175/497 (35%), Gaps = 98/497 (19%)
Query: 1 MFSQQQQQQLQ--QQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRG 58
++ +Q Q LQ Q+Q Q Q + QQQL QL L + Q + + + +
Sbjct: 31 LYERQAVQALQALQRQPNAAQYFHQFMLQQQLSNAQLHSLAAVQQATIAASRQASSPNTS 90
Query: 59 LPPQQPQ--QPLLNLQGTNSASLLNGSML---QRALLLQQLQGLDQFAMPPATYDTAGLT 113
QQ Q +NL T++A L++ S A L Q L PP A +
Sbjct: 91 TTQQQTTTTQASINLATTSAAQLISRSQSVSSPSATTLTQSVLLGNTTSPPLNQSQAQMY 150
Query: 114 MPTATLGNL----RGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPM 169
+ LGNL R G P LA+ + P A +QQ P A + +
Sbjct: 151 L-RPQLGNLLQVNRTLGRNVP-LASQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNL 208
Query: 170 NPSQFNLSGRNPQKQARTSSSTTPNRK------DSSSQTMPVEDKSD------------- 210
S + PQ Q T + P +SSQ + V S
Sbjct: 209 AVRNQQASAQGPQMQGSTQKAIPPGASPVSSLSQASSQALAVAQASSGATNQSLNLSQAG 268
Query: 211 --------------------------PPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRT 244
P G + PR T Q LP +
Sbjct: 269 GGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMGGGSCPRKGTGVVQPLPAA-------QTV 321
Query: 245 PAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALE 304
+ EA AK+ E + GQ V R P +QT L+ A
Sbjct: 322 TVSQGSQTEAESAAAKK-------AEADGSGQQNV-GMNLTRTATPAPSQT--LISSATY 371
Query: 305 AQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQ---KQAQTQTSPEHLVLQQKQV 361
Q+ P ++Q Q Q+ Q + + + + Q +Q+Q + HL L Q+Q
Sbjct: 372 TQIQPH---SLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATHLQLAQQQQ 428
Query: 362 QPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPE 421
Q Q QQ Q+Q QPQ T P QP + PP Q PP Q+ +Q T +L +
Sbjct: 429 QQQQQQ----QQQQQPQATTLTAP--QPPQVPPTQ--QVPPSQSQQQAQTLVVQPML--Q 478
Query: 422 QTPVVVHVCGLEMPPDA 438
+P L +PPDA
Sbjct: 479 SSP-------LSLPPDA 488
Score = 57.0 bits (136), Expect = 7e-08
Identities = 76/345 (22%), Positives = 126/345 (36%), Gaps = 48/345 (13%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63
Q +Q QL LQ QQQQ QQQQ QQQQ Q L PPQ P ++ +PP Q
Sbjct: 408 QHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVP----PTQQVPPSQ 463
Query: 64 PQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPT-ATLGNL 122
QQ + L++Q + ++PP + + + + +
Sbjct: 464 SQQQ------------------AQTLVVQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPI 505
Query: 123 RGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLG--------PPPVGVP--MNPS 172
+ + + ++A PP + + P + LG P G+P +
Sbjct: 506 KPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSG 565
Query: 173 QFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRM-DTP----- 226
Q +L+ P QA + P PV+ + +G + P + P
Sbjct: 566 QAHLASSPPSSQAPGALQECPPTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPAAFYM 625
Query: 227 EDQDLPPCPEDIAKEKRTPAPEPE---PCEASELPAKRLRSSEEPTEKEPPGQLQVKAQP 283
+ LP P+ +A +++ + E S LPAK +E P + L KA+
Sbjct: 626 QSVHLPGKPQTLAVKRKADSEEERDDVSTLGSMLPAKASPVAESPKVMDEKSSLGEKAES 685
Query: 284 QARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQP 328
A + TP E + P P L + ++ ++P
Sbjct: 686 VANV----NANTPS--SELVALTPAPSVPPPTLAMVSRQMGDSKP 724
>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
sapiens]
Length = 1077
Score = 63.9 bits (154), Expect = 6e-10
Identities = 74/260 (28%), Positives = 94/260 (36%), Gaps = 33/260 (12%)
Query: 161 GPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAE 220
GPPP+ P P F + R P R P D + MP PP G
Sbjct: 42 GPPPLMRP--PPPFGMM-RGPPPPPRPPFGRPPF--DPNMPPMPPPGGIPPPMGPPHLQR 96
Query: 221 PRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVK 280
P P +PP P + P P A PA K P G++
Sbjct: 97 PPFMPPPMSSMPPPPGMMFP------PGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYY 150
Query: 281 AQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 340
AR T+ PD + ++++ P +L QAQVQ+Q Q + Q Q +
Sbjct: 151 ---NARTRESAWTK-PDGVKVIQQSELTP-----MLAAQAQVQAQAQAQ-----AQAQAQ 196
Query: 341 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQ 400
Q QAQ Q Q Q Q Q Q +A+ Q Q Q Q QAQ Q Q Q VQ
Sbjct: 197 AQAQAQAQA--------QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQ 248
Query: 401 PPEQTHEQPHTQPQVSLLAP 420
Q + P S AP
Sbjct: 249 AQVQAQAVGASTPTTSSPAP 268
Score = 55.8 bits (133), Expect = 2e-07
Identities = 92/438 (21%), Positives = 140/438 (31%), Gaps = 53/438 (12%)
Query: 26 QQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP-QQPQQPLLNLQGTNSASLLNGSM 84
+ ++ +L QQ + AP P AV RG PP +P P ++G
Sbjct: 10 ESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPR----- 64
Query: 85 LQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLAT 144
F PP +D MP G P + P L P
Sbjct: 65 -------------PPFGRPP--FDPNMPPMPPP--------GGIPPPMGPPHLQRPPFMP 101
Query: 145 PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMP 204
P + P G PPV P P+ P + + TP+ K
Sbjct: 102 PPMSSMPPPPGMMFPPGMPPVTAPGTPAL-------PPTEEIWVENKTPDGKVYYYNART 154
Query: 205 VEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRS 264
E P+G + + + TP + + A +A + A+
Sbjct: 155 RESAWTKPDGVKVIQQSEL-TPMLAAQAQVQAQAQAQAQAQAQAQAQAQA-QAQAQAQAQ 212
Query: 265 SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQS 324
++ + + Q Q +AQ QA+ Q Q + ++AQ + P V +
Sbjct: 213 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVST 272
Query: 325 QTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQ 384
T PS+ T AQT ++P Q Q A P V T
Sbjct: 273 STSSSTPSSTTSTTTTATSVAQTVSTP----TTQDQTPSSAVSVATPTVSVSTPAPTATP 328
Query: 385 PSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGG- 443
PQ HP PP PH+ PQ + P PV+V + +P + G
Sbjct: 329 VQTVPQPHP----QTLPP----AVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGV 380
Query: 444 --GMEKTLPEPVGTQVSM 459
GM + + QV++
Sbjct: 381 LPGMAPPIVPMIHPQVAI 398
Score = 40.0 bits (92), Expect = 0.009
Identities = 77/311 (24%), Positives = 106/311 (34%), Gaps = 44/311 (14%)
Query: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQ-QLLQQSPPQAPLPM-AVSRGLPPQ 62
Q Q Q Q Q Q Q Q Q Q Q+Q Q Q+Q Q + S P P AVS
Sbjct: 218 QAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSS 277
Query: 63 QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNL 122
P T S + S+ Q A+ AT T ++ P T +
Sbjct: 278 TP-------SSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVAT-PTVSVSTPAPTATPV 329
Query: 123 RGYGMASPGLAAP----SLTPPQLATPNLQQFFPQATRQSLLGPP-----------PVGV 167
+ P P S+ P A P R L G P P V
Sbjct: 330 QTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIV 389
Query: 168 PMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPE 227
PM Q ++ T+ S K + +T +++ E E + E
Sbjct: 390 PMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRT-----LESTWEKPQELKE 444
Query: 228 DQDLPPCPEDIAKEKRTPAPEPEPCEA-----SELPAKRLR---SSEEPTEKEPPGQLQV 279
+ L E I + + P+ EP P E E P K ++ EE TE+E Q
Sbjct: 445 KEKL---EEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQ--- 498
Query: 280 KAQPQARMTVP 290
KA+P A +P
Sbjct: 499 KAKPVATAPIP 509
>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
sapiens]
Length = 1098
Score = 63.9 bits (154), Expect = 6e-10
Identities = 74/260 (28%), Positives = 94/260 (36%), Gaps = 33/260 (12%)
Query: 161 GPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAE 220
GPPP+ P P F + R P R P D + MP PP G
Sbjct: 42 GPPPLMRP--PPPFGMM-RGPPPPPRPPFGRPPF--DPNMPPMPPPGGIPPPMGPPHLQR 96
Query: 221 PRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVK 280
P P +PP P + P P A PA K P G++
Sbjct: 97 PPFMPPPMSSMPPPPGMMFP------PGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYY 150
Query: 281 AQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 340
AR T+ PD + ++++ P +L QAQVQ+Q Q + Q Q +
Sbjct: 151 ---NARTRESAWTK-PDGVKVIQQSELTP-----MLAAQAQVQAQAQAQ-----AQAQAQ 196
Query: 341 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQ 400
Q QAQ Q Q Q Q Q Q +A+ Q Q Q Q QAQ Q Q Q VQ
Sbjct: 197 AQAQAQAQA--------QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQ 248
Query: 401 PPEQTHEQPHTQPQVSLLAP 420
Q + P S AP
Sbjct: 249 AQVQAQAVGASTPTTSSPAP 268
Score = 55.8 bits (133), Expect = 2e-07
Identities = 114/574 (19%), Positives = 188/574 (32%), Gaps = 94/574 (16%)
Query: 26 QQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP-QQPQQPLLNLQGTNSASLLNGSM 84
+ ++ +L QQ + AP P AV RG PP +P P ++G
Sbjct: 10 ESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPR----- 64
Query: 85 LQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLAT 144
F PP +D MP G P + P L P
Sbjct: 65 -------------PPFGRPP--FDPNMPPMPPP--------GGIPPPMGPPHLQRPPFMP 101
Query: 145 PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMP 204
P + P G PPV P P+ P + + TP+ K
Sbjct: 102 PPMSSMPPPPGMMFPPGMPPVTAPGTPAL-------PPTEEIWVENKTPDGKVYYYNART 154
Query: 205 VEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRS 264
E P+G + + + TP + + A +A + A+
Sbjct: 155 RESAWTKPDGVKVIQQSEL-TPMLAAQAQVQAQAQAQAQAQAQAQAQAQA-QAQAQAQAQ 212
Query: 265 SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQS 324
++ + + Q Q +AQ QA+ Q Q + ++AQ + P V +
Sbjct: 213 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVST 272
Query: 325 QTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQ 384
T PS+ T AQT ++P Q Q A P V T
Sbjct: 273 STSSSTPSSTTSTTTTATSVAQTVSTP----TTQDQTPSSAVSVATPTVSVSTPAPTATP 328
Query: 385 PSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGG 444
PQ HP PP PH+ PQ + P PV+V PP V G
Sbjct: 329 VQTVPQPHP----QTLPP----AVPHSVPQPTTAIPAFPPVMV-------PPFRVPLPG- 372
Query: 445 MEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRA 504
+P P+ M+ + +C + +PG+
Sbjct: 373 ----MPIPLPGVAMMQIV----SCPYVKTVATTKTGVLPGM------------------- 405
Query: 505 FSTVPLTPVPRPSDSVSSTPA--ATSTPSKQALQFFCYICKASCSSQQEFQDHMSEPQHQ 562
P+ P+ P +++++PA A +T + ++ K + + + +PQ
Sbjct: 406 --APPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQEL 463
Query: 563 QRLGEIQHMSQACLL--SLLPVPRDVLETEDEEP 594
+ +++ + + S P+P +ETE+E+P
Sbjct: 464 KEKEKLEEKIKEPIKEPSEEPLP---METEEEDP 494
Score = 33.5 bits (75), Expect = 0.85
Identities = 75/319 (23%), Positives = 109/319 (34%), Gaps = 39/319 (12%)
Query: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQ-QLLQQSPPQAPLPM-AVSRGLPPQ 62
Q Q Q Q Q Q Q Q Q Q Q+Q Q Q+Q Q + S P P AVS
Sbjct: 218 QAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSS 277
Query: 63 QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMP------PATYDTAGLTMP- 115
P T +A+ + ++ Q A P PA T T+P
Sbjct: 278 TPSS---TTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQ 334
Query: 116 --TATLGNLRGYGMASPGLAAPS----LTPP-QLATPNLQQFFPQATRQSLLGPPPVGVP 168
TL + + P A P+ + PP ++ P + P ++ P V
Sbjct: 335 PHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTV 394
Query: 169 MNPSQFNLSGR--------NPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAE 220
L G +PQ S +T S T + E
Sbjct: 395 ATTKTGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLE 454
Query: 221 PRMDTPED-QDLPPCPEDIAKEKRTPAPEPEPCEA-----SELPAKRLR---SSEEPTEK 271
+ P++ ++ E I + + P+ EP P E E P K ++ EE TE+
Sbjct: 455 STWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEE 514
Query: 272 EPPGQLQVKAQPQARMTVP 290
E Q KA+P A +P
Sbjct: 515 EKAAQ---KAKPVATAPIP 530
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 63.5 bits (153), Expect = 8e-10
Identities = 74/256 (28%), Positives = 117/256 (45%), Gaps = 25/256 (9%)
Query: 171 PSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQD 230
P LSG + +++ P ++SS Q V S P SE A E R P ++
Sbjct: 37 PGPDTLSGGSGGSESQEEEE--PQERNSSPQRPAV---SAPVGASEIAEETR---PGQRE 88
Query: 231 LPPCPEDIAKEKRTPAPEPEPC-EASELPAKRLRSSEEPTEKEPPGQLQV-KAQPQARMT 288
L + + ++ P P+ +P E + P L ++P + GQ Q+ + Q + +
Sbjct: 89 L-----QLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQD---GQQQLSQLQQEKHQS 140
Query: 289 VPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQ 348
V Q P+L + Q+ QP+ +Q Q ++Q Q Q ++ + Q Q LQ+Q Q Q
Sbjct: 141 VHHQELKPELQLMHQQQQL----QPQQVQEQQRLQQQ-QEQLQTQQAQEQQVLQQQEQLQ 195
Query: 349 TS-PEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEH-PPAQVSVQPPEQTH 406
E +LQQ+Q Q Q QQ + Q+Q+Q Q Q Q +Q Q+ Q Q +Q
Sbjct: 196 QQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLL 255
Query: 407 EQPHTQPQVSLLAPEQ 422
+Q Q Q LL +Q
Sbjct: 256 QQQQAQLQQQLLEQQQ 271
Score = 59.3 bits (142), Expect = 1e-08
Identities = 50/107 (46%), Positives = 59/107 (55%), Gaps = 19/107 (17%)
Query: 5 QQQQQLQQQ-------QQQLQQLQQQQL--QQQQLQQQQLLQLQQLLQQSPPQAPLPMAV 55
QQQ+QLQQQ QQQ +QLQQQQL QQ+QLQQQQ Q Q+ LQQ Q L +
Sbjct: 189 QQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQ---QQQLLLLQ 245
Query: 56 SRGLPPQQPQQPLLNLQGTNSASLL---NGSMLQRALLLQQLQGLDQ 99
+G Q QQ LL Q L + LQ+ LLLQQ + L Q
Sbjct: 246 QQG----QLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQ 288
Score = 57.4 bits (137), Expect = 5e-08
Identities = 40/96 (41%), Positives = 47/96 (48%)
Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
M QQQ Q Q Q+QQ Q QQ+QLQ QQ Q+QQ+LQ Q+ LQQ + L L
Sbjct: 153 MHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQ 212
Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG 96
QQ Q LQ Q+ LLL Q QG
Sbjct: 213 QQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQG 248
Score = 57.0 bits (136), Expect = 7e-08
Identities = 45/185 (24%), Positives = 85/185 (45%), Gaps = 5/185 (2%)
Query: 235 PEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQL--QVKAQPQARMTVPKQ 292
P+ + +++R + + + L+ E+ ++ QL Q + Q Q + + +Q
Sbjct: 161 PQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQ 220
Query: 293 TQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPE 352
Q + + Q+ + Q +LQ Q Q+Q Q + Q+Q +L +Q Q Q +
Sbjct: 221 EQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQL---LQQQQAQLQQQLLEQQQAQLQQQ 277
Query: 353 HLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQ 412
L+ QQ+Q+Q Q QQ+ Q+Q Q Q P ++P+E ++ + P + EQ Q
Sbjct: 278 LLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQ 337
Query: 413 PQVSL 417
+ L
Sbjct: 338 QRQEL 342
Score = 57.0 bits (136), Expect = 7e-08
Identities = 35/66 (53%), Positives = 40/66 (60%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63
QQQQ+QLQQQQQ L QQ QLQQQ LQQQQ QQLL+Q Q + + + QQ
Sbjct: 229 QQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQ 288
Query: 64 PQQPLL 69
QQ L
Sbjct: 289 QQQQQL 294
Score = 54.7 bits (130), Expect = 4e-07
Identities = 47/102 (46%), Positives = 57/102 (55%), Gaps = 9/102 (8%)
Query: 5 QQQQQLQQQQQQLQ--QLQQQQL--QQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSR--G 58
Q+QQ+LQQQQ+QLQ Q Q+QQ+ QQ+QLQQQ +Q QQLLQQ Q + +
Sbjct: 165 QEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQ--VQEQQLLQQQQEQLQQQQLLQQQEQ 222
Query: 59 LPPQQPQQPLLNLQGTNSASLL-NGSMLQRALLLQQLQGLDQ 99
L QQ QQ LQ LL LQ+ LL QQ L Q
Sbjct: 223 LQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQ 264
Score = 53.9 bits (128), Expect = 6e-07
Identities = 65/261 (24%), Positives = 109/261 (41%), Gaps = 10/261 (3%)
Query: 171 PSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQ- 229
P + N S + P A +S + + ++ PE ++ ++ P+
Sbjct: 57 PQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQHEQLQQPQPHL 116
Query: 230 DLPPCPEDIAKEKRTPAPEPEPCEASELPAK-RLRSSEEPTEKEPPG-QLQVKAQPQARM 287
+L P+ +++ + + + K L+ + + +P Q Q + Q Q
Sbjct: 117 ELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQ 176
Query: 288 TVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQT 347
+Q Q +L + + Q + Q + Q Q Q+Q Q Q Q Q Q+Q Q
Sbjct: 177 LQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQ-QLLQQQEQLQQQQFQQQQEQL 235
Query: 348 QTSPEHLVLQQK-QVQPQL--QQEAEPQKQV--QPQVHTQAQPSVQPQEHPPAQVSVQPP 402
Q + L+LQQ+ Q+Q QL QQ+A+ Q+Q+ Q Q Q Q +Q QE Q Q
Sbjct: 236 QQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLL 295
Query: 403 EQTHEQ-PHTQPQVSLLAPEQ 422
+Q EQ Q Q L PE+
Sbjct: 296 QQQQEQLQQQQLQPPPLEPEE 316
Score = 51.6 bits (122), Expect = 3e-06
Identities = 39/69 (56%), Positives = 42/69 (60%), Gaps = 5/69 (7%)
Query: 5 QQQQQLQQQ--QQQLQQLQQQQLQQQ--QLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
QQQ QLQQQ QQQ QLQQQ L+QQ QLQQQ LLQ Q+ LQQ Q L + L
Sbjct: 245 QQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQ-LQ 303
Query: 61 PQQPQQPLL 69
QQ Q P L
Sbjct: 304 QQQLQPPPL 312
Score = 49.7 bits (117), Expect = 1e-05
Identities = 38/79 (48%), Positives = 45/79 (56%), Gaps = 10/79 (12%)
Query: 3 SQQQQQQLQQQQQQLQQ--LQQQQLQQQQLQQQQLLQLQQ-LLQQSPPQAPLPMAVSRGL 59
+Q QQQ L+QQQ QLQQ L QQQ Q QQ QQQQLLQ QQ LQQ Q P L
Sbjct: 260 AQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPP-------PL 312
Query: 60 PPQQPQQPLLNLQGTNSAS 78
P++ ++ L L + S
Sbjct: 313 EPEEEEEVELELMPVDLGS 331
Score = 43.1 bits (100), Expect = 0.001
Identities = 92/425 (21%), Positives = 159/425 (37%), Gaps = 53/425 (12%)
Query: 12 QQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNL 71
Q++ QLQQL+QQ QQQ Q +QL Q P P + P Q QQ L L
Sbjct: 86 QRELQLQQLEQQPEPQQQPQHEQL------------QQPQPHLELQQQPQQDGQQQLSQL 133
Query: 72 QGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPG 131
Q S+ + + L+ Q Q L P + L L +
Sbjct: 134 QQEKHQSVHHQELKPELQLMHQQQQL----QPQQVQEQQRLQQQQEQLQTQQ--AQEQQV 187
Query: 132 LAAPSLTPPQLATPN-LQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSS 190
L Q+ LQQ Q +Q LL + QF + Q+Q +
Sbjct: 188 LQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQE---QLQQQQF----QQQQEQLQQQQQ 240
Query: 191 TTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPE 250
++ Q ++ + + ++ E + + Q L E + ++++ +
Sbjct: 241 LLLLQQQGQLQQQLLQQQQ--AQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQ- 297
Query: 251 PCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPR 310
+ +L ++L+ P E E +++++ P + + + + E Q L R
Sbjct: 298 --QQEQLQQQQLQ--PPPLEPEEEEEVELELMP---VDLGSEQELEQQRQELERQQELER 350
Query: 311 FQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAE 370
Q Q+Q ++Q + Q + Q Q Q++ Q + +P L QQ++VQ +L
Sbjct: 351 -QQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLEL----- 404
Query: 371 PQKQVQPQVHTQAQPSV----QPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVV 426
VQP++ + P+ PA V V PP Q ++ +L P V
Sbjct: 405 --TPVQPELQLELVPAAGGGGAAVPGAPAAVVVAPPGYVVVQ-----ELMVLPAVAAPAV 457
Query: 427 VHVCG 431
V + G
Sbjct: 458 VAIPG 462
Score = 42.4 bits (98), Expect = 0.002
Identities = 42/111 (37%), Positives = 49/111 (44%), Gaps = 20/111 (18%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQL-------------QQQQLQQQQLLQLQQLLQQSPPQAP 50
QQ QQ QQQ QLQQ + Q + QQQQLQ QQ+ Q QQ LQQ Q
Sbjct: 120 QQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQV-QEQQRLQQQQEQLQ 178
Query: 51 LPMAVSRGLPPQQPQQPLLNLQGTNSASLL--NGSMLQRALLLQQLQGLDQ 99
A + + QQ Q Q LL LQ+ LLQQ + L Q
Sbjct: 179 TQQAQEQQVLQQQEQLQ----QQVQEQQLLQQQQEQLQQQQLLQQQEQLQQ 225
Score = 42.4 bits (98), Expect = 0.002
Identities = 31/74 (41%), Positives = 45/74 (60%), Gaps = 6/74 (8%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQLQ---QQQLQQ--QQLLQLQQLLQQSPPQAPLPMAVSRG 58
+QQ+Q+L++QQ+ +Q +Q+QLQ Q++LQQ QQL Q QQ L+Q Q L V G
Sbjct: 336 EQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLEL-TPVELG 394
Query: 59 LPPQQPQQPLLNLQ 72
Q+ Q L +Q
Sbjct: 395 AQQQEVQLELTPVQ 408
Score = 40.8 bits (94), Expect = 0.005
Identities = 42/111 (37%), Positives = 48/111 (43%), Gaps = 20/111 (18%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQ----LQQQQLQ--QQQLLQLQQLLQQS------PPQAPL 51
Q +QQ QQQ Q +QLQQ Q LQQQ Q QQQL QLQQ QS P+ L
Sbjct: 93 QLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQL 152
Query: 52 --------PMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQL 94
P V QQ Q+ L Q L LQ+ + QQL
Sbjct: 153 MHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQL 203
Score = 39.7 bits (91), Expect = 0.012
Identities = 28/66 (42%), Positives = 39/66 (59%), Gaps = 4/66 (6%)
Query: 4 QQQQQQLQQQ-QQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQ 62
QQ+Q+QLQ + Q++LQQL+QQ QQQQ +QQ +QL+ + Q V L P
Sbjct: 351 QQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQ---QQEVQLELTPV 407
Query: 63 QPQQPL 68
QP+ L
Sbjct: 408 QPELQL 413
Score = 37.7 bits (86), Expect = 0.045
Identities = 19/47 (40%), Positives = 33/47 (70%), Gaps = 5/47 (10%)
Query: 7 QQQLQQQQQQLQQLQQQQLQQQQLQ-----QQQLLQLQQLLQQSPPQ 48
+Q+L+QQ+Q+L++ Q+ + QQ+Q Q Q++L QL+Q L+Q Q
Sbjct: 332 EQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQ 378
Score = 31.6 bits (70), Expect = 3.2
Identities = 47/175 (26%), Positives = 64/175 (36%), Gaps = 47/175 (26%)
Query: 4 QQQQQQLQQQQQQLQQLQQQ----------------------------------QLQQQQ 29
QQQQQ LQQQQ+QLQQ Q Q + QQ+
Sbjct: 289 QQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQEL 348
Query: 30 LQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRAL 89
+QQ+ QLQ LQ+ Q + + L QQ Q +Q + L + L
Sbjct: 349 ERQQEQRQLQLKLQEELQQ------LEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQL 402
Query: 90 LLQQLQGLDQFAMPPATYDTAGLT--MPTATLGNLRGYG-----MASPGLAAPSL 137
L +Q Q + PA P A + GY M P +AAP++
Sbjct: 403 ELTPVQPELQLELVPAAGGGGAAVPGAPAAVVVAPPGYVVVQELMVLPAVAAPAV 457
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 63.5 bits (153), Expect = 8e-10
Identities = 83/367 (22%), Positives = 137/367 (37%), Gaps = 75/367 (20%)
Query: 130 PGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGR---------- 179
P P + PP+ P + P A + PP VP P + +
Sbjct: 10491 PPTKVPEVLPPKEVVPEKKVPVPPAKKPEA---PPPKVPEAPKEVVPEKKVPVPPPKKPE 10547
Query: 180 -NPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEE-----------AAEPRMDTPE 227
P K + P +K + +P + +S PPE E AA P+
Sbjct: 10548 VPPTKVPEVPKAAVPEKK--VPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVT 10605
Query: 228 DQDLPPCPEDIAKEKRTPAPEPE-----PCEASELPAKRLRSS----------------- 265
+P P+++ EK+ P P P+ P + E+P +
Sbjct: 10606 PVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEV 10665
Query: 266 -EEPTE---KEPPGQLQVKAQPQA--RMTVPKQTQTPDLLPEALEAQVLPRFQP-RVLQV 318
EEP E +EPP ++ + +P A ++TVP + P+ A+ A+ P P +V +V
Sbjct: 10666 FEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAK-KPELPPVKVPEV 10724
Query: 319 QAQVQSQTQ-----PRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQK 373
+V + + P+ P P++ K+ V+ +K+V + E P K
Sbjct: 10725 PKEVVPEKKVPLVVPKKPEAPPAKVPEVPKE----------VVPEKKVAVPKKPEVPPAK 10774
Query: 374 QVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPV-VVHVCGL 432
P+V + +P P + PPE E P+ + E+ PV V
Sbjct: 10775 --VPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEP 10832
Query: 433 EMPPDAV 439
E+PP AV
Sbjct: 10833 EVPPPAV 10839
Score = 58.5 bits (140), Expect = 2e-08
Identities = 54/248 (21%), Positives = 101/248 (40%), Gaps = 22/248 (8%)
Query: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
P+K P K + V + PE P+ + P +P P+
Sbjct: 9954 PRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVP 10013
Query: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEP-PGQLQVKAQPQARMTVPKQTQTPDLL 299
E++ P P P+ EA + P +K P P +V+A P VPK+ L+
Sbjct: 10014 EEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKK-----LI 10068
Query: 300 PEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQK 359
PE + +P+ +V+A P++P V + + + E ++ ++
Sbjct: 10069 PEEKKPTPVPK------KVEA-----PPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEE 10117
Query: 360 QVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQ-THEQPHTQPQVSLL 418
+V P+ ++ +++V P+ + + + +E PP + V P E+ E+ P+ +L
Sbjct: 10118 EVLPEEEEVLPEEEEVLPE---EEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVL 10174
Query: 419 APEQTPVV 426
PE P V
Sbjct: 10175 -PEVKPKV 10181
Score = 51.6 bits (122), Expect = 3e-06
Identities = 75/330 (22%), Positives = 130/330 (39%), Gaps = 46/330 (13%)
Query: 129 SPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGP-----PPVGVPMNPSQFNLSGRNPQK 183
+P + A P + P + + + L+ P PP VP P + P+K
Sbjct: 10706 APAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVV-----PEK 10760
Query: 184 Q-ARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEK 242
+ A P K PV ++ E A P + E+ + E+IA E+
Sbjct: 10761 KVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEE 10820
Query: 243 RTPAP-----EPE--PCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQT 295
P P EPE P E P K + + P K+P + +P+ + PK
Sbjct: 10821 EKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPR 10880
Query: 296 P----------DLLPEALEAQVLPRFQ-PRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQ 344
P D+ + + + +P+ + P QV +V+ T ++P + +V+ KL +
Sbjct: 10881 PPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVE-LTPLKVPGGEKKVR-KLLPE 10938
Query: 345 AQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQV-SVQPPE 403
+ + E ++ K V + +E EP +V+P+ + + P+ PP V V+ P
Sbjct: 10939 RKPEPKEEVVL---KSVLRKRPEEEEP--KVEPKKLEKVKKPAVPEPPPPKPVEEVEVPT 10993
Query: 404 QTHEQ---------PHTQPQVSLLAPEQTP 424
T + P +P + L APE P
Sbjct: 10994 VTKRERKIPEPTKVPEIKPAIPLPAPEPKP 11023
Score = 51.2 bits (121), Expect = 4e-06
Identities = 57/210 (27%), Positives = 85/210 (40%), Gaps = 14/210 (6%)
Query: 246 APEPEPCEASELPAKRLRSSEEPTE-KEPPGQLQVKAQPQARMT-VPKQTQTPDLLPEAL 303
A E E E + P K SE+ K+PP ++ + +P A++ VPK+ + +
Sbjct: 10427 AEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPE 10486
Query: 304 EAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQP 363
E +V P P VL + V + P P+ + P +A + PE V V P
Sbjct: 10487 EPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKV----PVPP 10542
Query: 364 QLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSL-LAPEQ 422
+ E P K P+V A P + E P + PPE P+ + AP +
Sbjct: 10543 PKKPEVPPTK--VPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPK 10600
Query: 423 TPVVVHVCGLEMPPDAVEAGGGMEKTLPEP 452
P V V E P + V EK +P P
Sbjct: 10601 KPEVTPVKVPEAPKEVVP-----EKKVPVP 10625
Score = 46.2 bits (108), Expect = 1e-04
Identities = 63/302 (20%), Positives = 118/302 (39%), Gaps = 58/302 (19%)
Query: 163 PPVGVPMNPSQFNLSGRNPQ---KQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAA 219
PP VP P + + P K+ P +++ PV P+ E
Sbjct: 10056 PPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKRE------PVPVPVALPQEEEVLF 10109
Query: 220 EPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPC--EASELPAKRLRSSEEPTEKEPPGQL 277
E + PE++ LP E++ E+ PE E E E+P P E+E P +
Sbjct: 10110 EEEI-VPEEEVLPE-EEEVLPEEEEVLPEEEEVLPEEEEIP---------PEEEEVPPEE 10158
Query: 278 QVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQ---PRIPSTD 334
+ P+ VP++ P++ P+ +P + +V + + + + + ++P
Sbjct: 10159 EY--VPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVP 10216
Query: 335 TQVQPK---LQKQ-----AQTQTSPEHLVLQQKQV---QPQLQQEAEPQKQVQPQVHTQA 383
+V+ K L K+ + PE + ++++ P +++ E P+V +A
Sbjct: 10217 KKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKA 10276
Query: 384 QPSV-----QPQEHPPAQVSVQ---------------PPEQTHEQPHTQPQVSLLAPEQT 423
P + E PPA+VS + PP + E P P+ +L P++
Sbjct: 10277 VPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKE 10336
Query: 424 PV 425
V
Sbjct: 10337 AV 10338
Score = 46.2 bits (108), Expect = 1e-04
Identities = 79/369 (21%), Positives = 148/369 (40%), Gaps = 66/369 (17%)
Query: 139 PPQLATPNLQQFFPQATRQSLLGPP-PVGVPMNPSQFNLSGRN---PQKQARTSSST--T 192
P + P ++F P+ + P PV P+ + ++ + P+K+ +
Sbjct: 10156 PEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEV 10215
Query: 193 PNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK----------EK 242
P + + +P E++ P E +EE E + E + PP E++ + +K
Sbjct: 10216 PKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKK 10275
Query: 243 RTP-APEPEPCEASELPAKRLRSSEE-----PTEKE--PPGQLQ--VKAQPQARMTVPKQ 292
P AP P P + PAK + E P +K+ PP ++ K P+ ++ VPK+
Sbjct: 10276 AVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKK 10335
Query: 293 TQTPDLLPE-ALEAQVLPRFQPRVL---QVQAQVQSQTQPRIPSTDT--QVQPKLQ---- 342
P LE +V F+ V+ +++ +V IP + +V+ +
Sbjct: 10336 EAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEF 10395
Query: 343 -------KQAQTQTSPEHL---------VLQQKQVQPQLQQEAEPQ-KQVQPQVHTQAQP 385
K Q + EH V + ++V+ + +A P+ ++ ++ +P
Sbjct: 10396 HEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKP 10455
Query: 386 --SVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGG 443
V P++ PPA+V P + E+ P+ + P + P V +PP V
Sbjct: 10456 PTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEV-------LPPKEVVP-- 10506
Query: 444 GMEKTLPEP 452
EK +P P
Sbjct: 10507 --EKKVPVP 10513
Score = 46.2 bits (108), Expect = 1e-04
Identities = 79/344 (22%), Positives = 132/344 (38%), Gaps = 81/344 (23%)
Query: 163 PPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVED---KSDPPEGSEEAA 219
PP VP P + L + + S P + + P E+ + + P E
Sbjct: 10771 PPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEE 10830
Query: 220 EPRMDTPEDQDLPPCPEDIAKEKRTP------AP---EPEPCEASELPAKRLRSSEEPTE 270
EP + P +P P+ I EK+ P AP EPEP + E P +L+ P
Sbjct: 10831 EPEVPPPA---VPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKP--KLKPRPPPPP 10885
Query: 271 KEPPGQ------LQVKAQPQARMTVPKQTQTPDLL----------------------PEA 302
PP + Q+KA P+ + VP++ Q P+ + PE
Sbjct: 10886 PAPPKEDVKEKIFQLKAIPKKK--VPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEP 10943
Query: 303 LEAQVL------------PRFQPRVLQ-VQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQT 349
E VL P+ +P+ L+ V+ + P P + +V P + K+ +
Sbjct: 10944 KEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEV-PTVTKRERKIP 11002
Query: 350 SPEHLVLQQKQVQPQLQQEA-EPQKQVQPQVHTQAQPSVQPQEHP---PAQVSVQPPEQT 405
P + +++P + A EP+ + + +V T P V+P+ P P V V +
Sbjct: 11003 EPTKV----PEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAE 11058
Query: 406 HEQPH---TQPQVSLL-APEQTPVVVHV--------CGLEMPPD 437
+ P +P+ + P++TP + G E PPD
Sbjct: 11059 AKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPPD 11102
Score = 42.0 bits (97), Expect = 0.002
Identities = 45/262 (17%), Positives = 105/262 (40%), Gaps = 34/262 (12%)
Query: 222 RMDTPEDQDLPPCPEDIAKEKRTPAPEP---------------EPCEASELPAKRLRSSE 266
+++ P +P P+ I EK+ PAP P +P ++P K ++ E
Sbjct: 9571 KIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEE 9630
Query: 267 EPTEKEPPGQLQVKAQPQARMTVPKQTQTPD---------LLPEALEAQVLPRFQ----P 313
K +Q+ + + + V K+ P +PE ++ P+ +
Sbjct: 9631 PLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPA 9690
Query: 314 RVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQK 373
+V + + +V + + I + + QP +++ + L+++ V Q ++E E +
Sbjct: 9691 KVTEFRKRVVKEEKVSIEAPKREPQP-IKEVTIMEEKERAYTLEEEAVSVQREEEYEEYE 9749
Query: 374 QVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQ--VSLLAPEQTPVVVHVCG 431
+ + + +P+ + ++ + + HE+ T+P+ + + + PV
Sbjct: 9750 EYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKP-- 9807
Query: 432 LEMPPDAVEAGGGMEKTLPEPV 453
+ PP V E+ +P P+
Sbjct: 9808 -KAPPAKVLKKAVPEEKVPVPI 9828
Score = 41.6 bits (96), Expect = 0.003
Identities = 53/265 (20%), Positives = 101/265 (38%), Gaps = 23/265 (8%)
Query: 203 MPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPE----PCEASELP 258
+P+ K +PP + P+ PE++ P P+ KE P PE P ++P
Sbjct: 9303 VPIPKKVEPP-APKVPEVPKKPVPEEKKPVPVPK---KEPAAPPKVPEVPKKPVPEEKIP 9358
Query: 259 AKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQV------LPRFQ 312
+ E P K P Q V + + + ++ P +PE + +V +PR +
Sbjct: 9359 VPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKE 9418
Query: 313 PRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQA---QTQTSPEHLVLQQKQVQPQLQQEA 369
V +V + + +P V + K+A + + S + +V +++ V + A
Sbjct: 9419 EEV-PPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFA 9477
Query: 370 EPQKQVQPQVHTQAQPS-VQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVV- 427
PQ+ + A+ +E +SV E+ E+ + + E VV
Sbjct: 9478 VPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVE 9537
Query: 428 ---HVCGLEMPPDAVEAGGGMEKTL 449
H+ + + E EK +
Sbjct: 9538 EKLHIISKRVEAEPAEVTERQEKKI 9562
Score = 40.4 bits (93), Expect = 0.007
Identities = 54/244 (22%), Positives = 99/244 (40%), Gaps = 40/244 (16%)
Query: 248 EPEPCEASELPAKRLRSSEEPTE-KEPPGQLQVKAQPQARMTVP---KQTQTPDLLPEA- 302
EPE +P K + PT+ K PP ++ KA P+ ++ VP K P +PE
Sbjct: 9788 EPE----KPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEP 9843
Query: 303 -------LEAQVLPRFQPRVLQVQAQVQSQ-----TQPRIPSTDTQVQPKLQ-KQAQTQT 349
+ + R + +V + A+V + + ++P +V P ++ + +
Sbjct: 9844 KKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKEL 9903
Query: 350 SPEHLVLQQK---QVQPQLQQEAEPQKQVQPQVHTQAQ---------PSVQPQEHPPAQV 397
PE + +++ V+ L +E E + + T+ + P V + P +
Sbjct: 9904 EPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKK 9963
Query: 398 SVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDA----VEAGGGMEKTLPEPV 453
V P++ P P+V E+ PV++ E PP A V E+ +P PV
Sbjct: 9964 PVPVPKKKEAPPAKVPEVPKKPEEKVPVLIP--KKEKPPPAKVPEVPKKPVPEEKVPVPV 10021
Query: 454 GTQV 457
+V
Sbjct: 10022 PKKV 10025
Score = 37.4 bits (85), Expect = 0.059
Identities = 41/227 (18%), Positives = 87/227 (38%), Gaps = 10/227 (4%)
Query: 187 TSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAA---EPRMDTPEDQDLPPCPEDIAKEKR 243
T S R D M + + + EG EPR + +L ++I E +
Sbjct: 8874 TESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKEIKLELK 8933
Query: 244 TPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEAL 303
P +P + + E P PP L + P+ + PK+ + +
Sbjct: 8934 PPDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLLPT-PEEKKPPPKRIEVTKKAVKKD 8992
Query: 304 EAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQP 363
+V+ + P+ + + ++ + P T + K + + E + + +
Sbjct: 8993 AKKVVAK--PKEMTPREEIVKKPPP----PTTLIPAKAPEIIDVSSKAEEVKIMTITRKK 9046
Query: 364 QLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPH 410
++Q+E E + + VH + + ++ E P ++ V+P + EQP+
Sbjct: 9047 EVQKEKEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQPY 9093
Score = 36.2 bits (82), Expect = 0.13
Identities = 66/340 (19%), Positives = 124/340 (36%), Gaps = 57/340 (16%)
Query: 213 EGSEEAAEPRMDTPEDQDLPPCPEDI---AKEKRTPAPEPE---PCEASELPAKRLRSSE 266
EG +E E + +++++ +++ + E++ PA PE P + + E
Sbjct: 9131 EGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIE 9190
Query: 267 EPTEKEPPGQLQVKAQPQ-ARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQ 325
+ + + ++QV P+ ++ VP++ + E +E +V P V + + +
Sbjct: 9191 KTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKV-----PAVHTKKMVISEE 9245
Query: 326 TQPRIPSTDTQVQ---PKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQ 382
T+ +V P++QK+ T+ V K+V+P + P+K +V
Sbjct: 9246 KMFFASHTEEEVSVTVPEVQKEIVTEEKIH--VAISKRVEPPPKVPELPEKPAPEEVAPV 9303
Query: 383 AQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAG 442
P P + P ++P P+ AP + P E+P V
Sbjct: 9304 PIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVP--------EVPKKPVP-- 9353
Query: 443 GGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDS 502
E+ +P PV + + A V E + G K+TI+ +
Sbjct: 9354 ---EEKIPVPVA--------KKKEAPPAKVPEVQK---------GVVTEEKITIVTQREE 9393
Query: 503 RAFSTVP----------LTPVPRPSDSVSSTPAATSTPSK 532
VP PVPR + V P + P K
Sbjct: 9394 SPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKK 9433
Score = 35.8 bits (81), Expect = 0.17
Identities = 32/175 (18%), Positives = 72/175 (41%), Gaps = 14/175 (8%)
Query: 235 PEDIAKEKRTPAPEPEPC-EASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQT 293
PE+I P P P E + P KR+ +++ +K+ + + R + K+
Sbjct: 8954 PEEIPPVVAPPIPLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKP 9013
Query: 294 QTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEH 353
P L +P P ++ V ++ + I + ++QK+ + +
Sbjct: 9014 PPPTTL--------IPAKAPEIIDVSSKAEEVKIMTITR-----KKEVQKEKEAVYEKKQ 9060
Query: 354 LVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQ 408
V ++K+V + +E + +V+P QP + + ++ V+ ++ HE+
Sbjct: 9061 AVHKEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEE 9115
Score = 35.8 bits (81), Expect = 0.17
Identities = 59/291 (20%), Positives = 108/291 (37%), Gaps = 48/291 (16%)
Query: 129 SPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTS 188
SP A P + P+ P ++ P+ + PPP VP P +
Sbjct: 9394 SPPPAVPEI--PKKKVPEERKPVPRKEEEV---PPPPKVPALPKK--------------- 9433
Query: 189 SSTTPNRKDSSSQTMPVEDKSDPP----------EGSEEAAEPRMDTPEDQDLPPCPEDI 238
P ++ + +PV K+ PP E AE ++ Q + ++
Sbjct: 9434 ----PVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEV 9489
Query: 239 AKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDL 298
+ E+ E E E + R EE E E + +V +P+ V ++
Sbjct: 9490 SAEEEWSYSEEE--EGVSISVYREEEREEEEEAEVT-EYEVMEEPE-EYVVEEKLHIISK 9545
Query: 299 LPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQ 358
EA A+V R + +++ +P+IP+ + P +A + PE V
Sbjct: 9546 RVEAEPAEVTERQEKKIV---------LKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAP 9596
Query: 359 KQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHP-PAQVSVQPPEQTHEQ 408
+ ++ P++ +P + P V E P PA+V+ + + T E+
Sbjct: 9597 VPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEE 9647
Score = 34.7 bits (78), Expect = 0.38
Identities = 56/302 (18%), Positives = 108/302 (35%), Gaps = 51/302 (16%)
Query: 137 LTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNP---QKQARTSSSTTP 193
+ P + P ++ P A + PPP VP P + + P + +A P
Sbjct: 10810 IAPEEEIAPEEEKPVPVAEEEEPEVPPPA-VPEEPKKIIPEKKVPVIKKPEAPPPKEPEP 10868
Query: 194 NRKDSSSQTMPVEDKSDPPEGSEEAAE--------PRMDTPEDQDLPPCPE--------- 236
+ + P P E+ E P+ PE +P E
Sbjct: 10869 EKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGG 10928
Query: 237 DIAKEKRTPAPEPEPCEASELPA---------------KRLRSSEEPTEKEPPG-----Q 276
+ K P +PEP E L + K+L ++P EPP +
Sbjct: 10929 EKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEE 10988
Query: 277 LQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQ 336
++V + +P+ T+ P++ P A LP +P+ + +A+V++ P + T
Sbjct: 10989 VEVPTVTKRERKIPEPTKVPEIKP----AIPLPAPEPKP-KPEAEVKTIKPPPVEPEPTP 11043
Query: 337 VQ-----PKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQE 391
+ P + K+A+ + E + ++ ++ P + + ++ + P E
Sbjct: 11044 IAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPPDE 11103
Query: 392 HP 393
P
Sbjct: 11104 AP 11105
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 63.2 bits (152), Expect = 1e-09
Identities = 90/360 (25%), Positives = 113/360 (31%), Gaps = 69/360 (19%)
Query: 130 PGLAAPSLT-PPQLATPNLQQFFPQATRQSLLGP----PPVGVPMNPSQFNLSGRNPQKQ 184
P A PS+T PP A P+LQ P SL P PP + ++ Q S +P Q
Sbjct: 365 PSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQ 424
Query: 185 ARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRT 244
A S T R+ +S T P S PP+ P + P LP P
Sbjct: 425 ATHSFLTMSPRQTQASLTSPSRPASTPPD------SPPLQAP--LSLPASPPLQTSLSPA 476
Query: 245 PAPEPEPCEASELPAKRLRSSEEPTEK-----EPPGQLQVK------AQPQARMTVPKQT 293
+P P L A +S P PP + Q P A +T P
Sbjct: 477 VSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLE 536
Query: 294 QTPDLLPEALEAQVLPRFQPRV----------LQVQAQVQSQTQPRIPST---------D 334
P L P L+ P P + LQ + P PS+
Sbjct: 537 NLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPP 596
Query: 335 TQVQPKLQKQAQTQTSPEHLVLQQKQVQPQL---QQEAEPQKQVQPQVHTQAQPSVQ--- 388
P LQ SP L Q P L +A P P + A PS Q
Sbjct: 597 ALASPPLQGLPSPPLSP--LATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPN 654
Query: 389 ------------PQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPP 436
P PP Q PP P P P Q P + L++PP
Sbjct: 655 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP------PSQAPPSLAAPPLQVPP 708
Score = 60.8 bits (146), Expect = 5e-09
Identities = 110/434 (25%), Positives = 147/434 (33%), Gaps = 64/434 (14%)
Query: 45 SPPQAPLPMAV-SRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRA---LLLQQLQGLDQF 100
SPP P A S PP Q L + L LQ L L LQ
Sbjct: 359 SPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSL 418
Query: 101 AMPPATYDTAGLTM-PTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSL 159
P + LTM P T +L SP + P+ TPP +P LQ SL
Sbjct: 419 GSPTLQATHSFLTMSPRQTQASL-----TSP--SRPASTPPD--SPPLQ------APLSL 463
Query: 160 LGPPPVGVPMNPSQFNLSGR---NPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSE 216
PP+ ++P+ LS +P + + +S +P SS P+E +S S
Sbjct: 464 PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523
Query: 217 EAAEPRMDTPEDQDLP---PCPEDIAKEKRT-------PAPEPEPCEA-----SELPAKR 261
+ + TP ++LP P P A T P P P P +A + P +
Sbjct: 524 QTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPET 583
Query: 262 LRSSEEPTEKEPPGQLQVKAQ-----PQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVL 316
S P + PP Q P + + P P L L+A P P +
Sbjct: 584 PSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLS 643
Query: 317 QVQAQ---------VQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQ 367
+ V P P VQ A SP Q P L
Sbjct: 644 PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS--ATPPSQAPPSL-- 699
Query: 368 EAEPQKQVQPQVHTQAQPSVQPQEHPPAQVS---VQPPEQTHEQPHTQPQVSLLA--PEQ 422
A P QV P A P + P PP Q PP Q P P +S A P +
Sbjct: 700 -AAPPLQVPPS--PPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPR 756
Query: 423 TPVVVHVCGLEMPP 436
P ++ L++PP
Sbjct: 757 VPPLLAAPPLQVPP 770
Score = 48.9 bits (115), Expect = 2e-05
Identities = 98/438 (22%), Positives = 156/438 (35%), Gaps = 60/438 (13%)
Query: 119 LGNLRGYGMASP---GLAAPSLTPPQLATPNLQQFFPQATRQSL---LGPPPVGVPMNPS 172
LG L +A+P G A + PP A L P + + L PP P +
Sbjct: 296 LGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQ 355
Query: 173 QFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLP 232
P QA S +T P + S QT+P P + P + P
Sbjct: 356 TLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP------PIQVPHSLTSPSLQA------P 403
Query: 233 PCPEDIAKEKRTPAPEPEPCEASE-----LPAKRLRSSEEPTE--KEPPGQLQVKAQPQA 285
P P ++ + T + +A+ P + S P+ PP ++A
Sbjct: 404 PSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSL 463
Query: 286 RMTVPKQTQ-TPDLLPEALEAQVLPRFQPRVL---QVQAQVQSQTQPRIPSTDTQVQPKL 341
+ P QT +P + P + + P L QA + S P + + + P L
Sbjct: 464 PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523
Query: 342 QKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQP 401
Q + T+P L P LQ + P P + T P+ P + PP+ ++ P
Sbjct: 524 QTPPASLTTPP-LENLPSLAPPPLQTASAP--LTTPHLETPPCPAPCPLQAPPSPLTTPP 580
Query: 402 PEQTHEQPHTQPQVSLLAPEQTPVVVH--VCGLEMPPDAVEAGGGMEKTLPEPVGTQVSM 459
PE T ++ P+ P + + GL PP + A T P +++
Sbjct: 581 PE-------TPSSIATPPPQAPPALASPPLQGLPSPPLSPLA------TPPPQAPPXLAL 627
Query: 460 EEIQNESA--CGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPS 517
+Q + + + + P +L V +LQ+ FS P PV P
Sbjct: 628 PPLQAPPSPPASPPLSPLATPSPQAP------NALAVHLLQA----PFSPPPSPPVQAPF 677
Query: 518 DSVSSTPAATS-TPSKQA 534
+S P + S TP QA
Sbjct: 678 SPPASPPVSPSATPPSQA 695
Score = 42.0 bits (97), Expect = 0.002
Identities = 74/307 (24%), Positives = 103/307 (33%), Gaps = 45/307 (14%)
Query: 162 PPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEP 221
P PV P S G QK R S+ T R ++ + P+ S +A
Sbjct: 111 PGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKAT----------EAPKRSALSAGA 160
Query: 222 RMDTPEDQDLPPCPEDIAKEKRT---------PAPEPEPCEASELPAKRLRSSEE--PTE 270
R DT P P +A+ R PAP P +E P K + S+ E TE
Sbjct: 161 RRDTSGPTPGTPSPA-MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE 219
Query: 271 KEPPGQLQVKA-----QPQARMTVPKQTQTPDLLPEALEAQVLPR-----FQPRVLQVQA 320
P + + A +P +R T A+ PR QP+ +QA
Sbjct: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA 279
Query: 321 QVQSQ-TQPR---------IPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAE 370
Q T PR + S+ +A+ P++ P A
Sbjct: 280 LRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLAT 339
Query: 371 PQKQVQPQVHTQAQPSVQPQEHPPAQVSVQ-PPEQTHEQPHTQPQVSLLAPEQTPVVVHV 429
P P A PS+Q PPA Q PP T P + + P Q P +
Sbjct: 340 PLPLAPPS--PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTS 397
Query: 430 CGLEMPP 436
L+ PP
Sbjct: 398 PSLQAPP 404
Score = 35.8 bits (81), Expect = 0.17
Identities = 86/318 (27%), Positives = 106/318 (33%), Gaps = 75/318 (23%)
Query: 42 LQQSP-PQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQF 100
LQ P P A LPM+ PPQ P AL LQ L
Sbjct: 766 LQVPPSPPASLPMSPLAKPPPQAPP----------------------ALATPPLQALPS- 802
Query: 101 AMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQ-QFFPQA--TRQ 157
PPA++ P+A+L SP P PP LA P LQ P A T Q
Sbjct: 803 --PPASFPGQAPFSPSASL-------PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ 853
Query: 158 SLLGPPPVGVPMNPS----QFNLSGRNPQKQARTSSSTTPN---RKDSSSQTMPVEDKSD 210
+ PP G + S L+ P +R+ SST SSS T E+
Sbjct: 854 APRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRG 913
Query: 211 PPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAP---------EPEPCEASELPAK- 260
G E A P D +L C A R PAP P P + P
Sbjct: 914 YDSGPEGGA--AASPPPDAELAACHP--AAWSRGPAPPLAFRGAPGAPLPWPPATGPGSA 969
Query: 261 ----RLRSSEEPTEKEP-PGQLQVKAQP-------------QARMTVPKQTQTPDLLPEA 302
+ +E P P PG L P A PKQ + +L A
Sbjct: 970 DGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGA 1029
Query: 303 LEAQVLPRFQPRVLQVQA 320
L+A V+ R L + A
Sbjct: 1030 LQASVVQHLLSRTLLLAA 1047
Score = 35.4 bits (80), Expect = 0.22
Identities = 55/232 (23%), Positives = 74/232 (31%), Gaps = 69/232 (29%)
Query: 46 PPQAPLPMAVSR-GLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPP 104
PPQAP P+A +PP P P ++ T + L +PP
Sbjct: 723 PPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV------------PPLLAAPPLQVPP 770
Query: 105 ATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPP 164
+ P A+L SP P PP LATP LQ L PP
Sbjct: 771 S---------PPASLP-------MSPLAKPPPQAPPALATPPLQ----------ALPSPP 804
Query: 165 VGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMD 224
P + F+ S P S TP PP+ A P +
Sbjct: 805 ASFP-GQAPFSPSASLPM-----SPLATP-----------------PPQAPPVLAAPLLQ 841
Query: 225 TPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQ 276
P PP + +R P P P+ + + RL + P PP +
Sbjct: 842 VPPS---PPASPTLQAPRRPPTPGPD----TSVSGPRLTLALAPGPPPPPSR 886
>gi|197276594 RNA binding motif protein 20 [Homo sapiens]
Length = 1227
Score = 62.8 bits (151), Expect = 1e-09
Identities = 42/140 (30%), Positives = 70/140 (50%), Gaps = 6/140 (4%)
Query: 639 KTPRKFVEHVKSQGH-KDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDE 697
+ P FV+ K++G +D A E LE++ + E + C E E +
Sbjct: 1057 RQPSPFVDDCKTRGTPEDGACEGSPLEEKASPPIETD---LQNQACQEVLTPENSRYVEM 1113
Query: 698 EEIEVEEELCKQVRSRD-ISREEWKGSETYSP-NTAYGVDFLVPVMGYICRICHKFYHSN 755
+ +EV +V + +S W+ + +S + GV+F+VP G+ C++C FY S
Sbjct: 1114 KSLEVRSPEYTEVELKQPLSLPSWEPEDVFSELSIPLGVEFVVPRTGFYCKLCGLFYTSE 1173
Query: 756 SGAQLSHCKSLGHFENLQKY 775
A++SHC+S H+ NLQKY
Sbjct: 1174 ETAKMSHCRSAVHYRNLQKY 1193
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 62.8 bits (151), Expect = 1e-09
Identities = 67/306 (21%), Positives = 117/306 (38%), Gaps = 45/306 (14%)
Query: 208 KSDPPEGSE--EAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSS 265
+SD EG E EA E + P D + + PE E EA E + S
Sbjct: 1828 QSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPES 1887
Query: 266 EEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQ 325
E+ E ++Q +++ K+ Q EALE + +
Sbjct: 1888 EDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETE-----------------GE 1930
Query: 326 TQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQ--- 382
+P + Q + ++A+ QT PE V++ ++ + + Q E+E + ++ +V TQ
Sbjct: 1931 DEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAE 1990
Query: 383 --AQPSVQPQEHPPAQ----------------VSVQPPEQTHEQPHTQPQVSLLAPEQTP 424
AQP + E P A+ V QP + E + + + P
Sbjct: 1991 GEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQP 2050
Query: 425 VVVHVCGLEMPPDAVEAGGGMEKTLPE--PVGTQVSMEEIQNES---ACGLDVGECENRA 479
V E +A EA G +++ E P V +E + E+ + G++ E E A
Sbjct: 2051 ESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEA 2110
Query: 480 REMPGV 485
++ G+
Sbjct: 2111 QKAEGI 2116
Score = 53.9 bits (128), Expect = 6e-07
Identities = 60/247 (24%), Positives = 102/247 (41%), Gaps = 26/247 (10%)
Query: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQ-DLPPCPEDI- 238
P+ + + + + P D + PE EEA E + E + + P ED+
Sbjct: 2027 PKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVD 2086
Query: 239 AKEKRTPA-PEPEPCEASELP--AKRLRSSEEPTEKEPPGQLQVKAQPQAR-MTVPKQTQ 294
A+E A PE E EA E A++ E P + + +AQP++ + P+
Sbjct: 2087 AQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAP-------ETEGEAQPESEGIEAPEAEG 2139
Query: 295 TPDLLPEALEAQVLP-RFQPRVLQVQAQ-VQSQTQPRIPSTDTQVQPKLQKQAQTQTSPE 352
E +EAQ QP ++AQ + + QP + + +A+ + PE
Sbjct: 2140 EAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAP-------EAEGEAQPE 2192
Query: 353 HLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQ--THEQPH 410
++ + + + Q E E + P+ +AQP + E P A+ QP + T +
Sbjct: 2193 SEGIEAPEAEGEAQPELEGVEA--PEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKK 2250
Query: 411 TQPQVSL 417
PQVSL
Sbjct: 2251 GSPQVSL 2257
Score = 45.4 bits (106), Expect = 2e-04
Identities = 87/440 (19%), Positives = 159/440 (36%), Gaps = 65/440 (14%)
Query: 182 QKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPE--DQDLPPCPEDIA 239
+ Q + TP ++ + P + ++ PE +EA +P ++ E + + PE
Sbjct: 1882 EAQPESEDVETP---EAEWEVQPESEGAEAPEAEKEA-QPETESVEALETEGEDEPESEG 1937
Query: 240 KEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLL 299
E + + E P + S+E E+ P V+A + V Q +
Sbjct: 1938 AEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEA---LEVEVETQEAEGEAQ 1994
Query: 300 PEALEAQVLPRFQPRVLQVQAQVQSQT-----QPRIPSTDTQVQPKLQKQAQTQTSPEHL 354
PE+ + + P + + + + + Q ++ QP+ + Q ++ + PE
Sbjct: 1995 PESEDVEA-PEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESD 2053
Query: 355 VLQQKQVQPQLQQEAEPQKQVQPQVHT------------QAQPSVQPQEHPPAQVSVQPP 402
++ + + + Q+ ++ + + H +AQP + E P A+ Q
Sbjct: 2054 GVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKA 2113
Query: 403 EQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDA--VEAGGGMEKTLPEPVG--TQVS 458
E E P T+ + PE + E P++ VEA + PE G Q +
Sbjct: 2114 EGI-EAPETEGEAQ---PESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEA 2169
Query: 459 MEEIQNESACGLDVGECENRAR-EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPS 517
EE Q E G++ E E A+ E G+ ++ A + P
Sbjct: 2170 EEEAQPELE-GVEAPEAEGEAQPESEGIEA----------PEAEGEAQPELEGVEAPEAE 2218
Query: 518 DSVSSTPAATSTPSKQALQFFCYICKASCSSQQEFQ-DHMSEPQHQQRLGEIQHMSQACL 576
+ P TP + +A S+ E Q + PQ G+ + S+
Sbjct: 2219 EEAQPEPEGVETPEAEG--------EAQPESEGETQGEKKGSPQVSLGDGQSEEASE--- 2267
Query: 577 LSLLPVPRDVLETEDEEPPP 596
S PVP D PPP
Sbjct: 2268 -SSSPVPED-----RPTPPP 2281
Score = 30.0 bits (66), Expect = 9.4
Identities = 23/89 (25%), Positives = 43/89 (48%), Gaps = 14/89 (15%)
Query: 645 VEHVKSQGHKD------KAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEE 698
VE ++++G + +A+E + +E GQ + +++ E +EE + + ED E
Sbjct: 1922 VEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQ---EAEEEAQPESEDVE 1978
Query: 699 EIEVEEELCK-----QVRSRDISREEWKG 722
+EVE E + Q S D+ E +G
Sbjct: 1979 ALEVEVETQEAEGEAQPESEDVEAPEAEG 2007
>gi|58530845 zyxin [Homo sapiens]
Length = 572
Score = 62.4 bits (150), Expect = 2e-09
Identities = 69/298 (23%), Positives = 109/298 (36%), Gaps = 26/298 (8%)
Query: 132 LAAPSLTPPQLATPNLQQFF-PQATRQSLLGPPPVGVPMNPSQFN---LSGRNPQKQART 187
+AAP +P + + F+ PQ ++ P P P P G + R
Sbjct: 1 MAAPRPSPAISVSVSAPAFYAPQKKFGPVVAPKPKVNPFRPGDSEPPPAPGAQRAQMGRV 60
Query: 188 SSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAP 247
P +D P+ D EG+ A P P ++ PP P +E+ P+P
Sbjct: 61 GEIPPPPPEDFPLPPPPLAGDGDDAEGALGGAFPPPPPPIEESFPPAP---LEEEIFPSP 117
Query: 248 EPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQV 307
P P E P + +P EK L++ + + K + +A+V
Sbjct: 118 PPPPEEEGG-PEAPIPPPPQPREKVSSIDLEIDSLSSLLDDMTKN--------DPFKARV 168
Query: 308 LPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQ 367
+ P + +S T+P + T P + + +Q P QV Q
Sbjct: 169 SSGYVPPPVATPFSSKSSTKPA--AGGTAPLPPWKSPSSSQPLP--------QVPAPAQS 218
Query: 368 EAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPV 425
+ + Q QPQ Q Q VQ Q P + + QP P P+ S + P+ TPV
Sbjct: 219 QTQFHVQPQPQPKPQVQLHVQSQTQPVSLANTQPRGPPASSPAPAPKFSPVTPKFTPV 276
>gi|4508047 zyxin [Homo sapiens]
Length = 572
Score = 62.4 bits (150), Expect = 2e-09
Identities = 69/298 (23%), Positives = 109/298 (36%), Gaps = 26/298 (8%)
Query: 132 LAAPSLTPPQLATPNLQQFF-PQATRQSLLGPPPVGVPMNPSQFN---LSGRNPQKQART 187
+AAP +P + + F+ PQ ++ P P P P G + R
Sbjct: 1 MAAPRPSPAISVSVSAPAFYAPQKKFGPVVAPKPKVNPFRPGDSEPPPAPGAQRAQMGRV 60
Query: 188 SSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAP 247
P +D P+ D EG+ A P P ++ PP P +E+ P+P
Sbjct: 61 GEIPPPPPEDFPLPPPPLAGDGDDAEGALGGAFPPPPPPIEESFPPAP---LEEEIFPSP 117
Query: 248 EPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQV 307
P P E P + +P EK L++ + + K + +A+V
Sbjct: 118 PPPPEEEGG-PEAPIPPPPQPREKVSSIDLEIDSLSSLLDDMTKN--------DPFKARV 168
Query: 308 LPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQ 367
+ P + +S T+P + T P + + +Q P QV Q
Sbjct: 169 SSGYVPPPVATPFSSKSSTKPA--AGGTAPLPPWKSPSSSQPLP--------QVPAPAQS 218
Query: 368 EAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPV 425
+ + Q QPQ Q Q VQ Q P + + QP P P+ S + P+ TPV
Sbjct: 219 QTQFHVQPQPQPKPQVQLHVQSQTQPVSLANTQPRGPPASSPAPAPKFSPVTPKFTPV 276
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 62.4 bits (150), Expect = 2e-09
Identities = 100/419 (23%), Positives = 151/419 (36%), Gaps = 61/419 (14%)
Query: 13 QQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQ 72
++Q L QLQQ Q Q Q Q Q +LQ L PP P P+ G QP P +
Sbjct: 54 REQHLAQLQQLQ-QMHQKQMQCVLQPHHL--PPPPLPPPPVMPGGGYGDWQPPPPPMPPP 110
Query: 73 GTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGL 132
+ S + +L Q G PP L + SP
Sbjct: 111 PGPALSYQKQQQYKHQMLHHQRDG------PPG----------------LVPMELESPPE 148
Query: 133 AAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTT 192
+ P PP P Q + P PP P P ++P Q+ + + +
Sbjct: 149 SPP--VPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPS 206
Query: 193 PNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPC 252
+ SSSQ+ +S P + P + Q L P P +T + EP
Sbjct: 207 YSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTV-QQEPL 265
Query: 253 EASELPAKRLRSSEEPTEKEP-PGQLQVKAQPQ---ARMTVPKQTQTPDLLPEALEAQVL 308
E+ AK + ++ EP P + + Q Q + + Q +T LP + V+
Sbjct: 266 ESG---AKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVV 322
Query: 309 PRFQPRVLQVQAQVQSQTQ---------PRIPSTDTQVQPKL-QKQAQTQTSPEHLVLQQ 358
+ P ++ + V + +Q P +P + +V P L ++ Q++ E L+Q
Sbjct: 323 AKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLKQ 382
Query: 359 KQV-----QPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQ 412
Q Q Q Q Q Q HTQ Q +Q Q +QPP PH Q
Sbjct: 383 LQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQY-----QQIIQPP------PHIQ 430
Score = 41.6 bits (96), Expect = 0.003
Identities = 77/312 (24%), Positives = 104/312 (33%), Gaps = 58/312 (18%)
Query: 11 QQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVS---RGLPPQQPQQP 67
QQ QQ Q Q + Q+ Q QQ+LQ Q + Q PP M+V R QQ Q
Sbjct: 391 QQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQ-TMSVDMQLRHYEMQQQQFQ 449
Query: 68 LLNLQGTNSASL-----------------------LNGSMLQRALLLQQL---------Q 95
L + L G M LQ+ Q
Sbjct: 450 HLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQ 509
Query: 96 GLDQFAMPPATYDTAGL-----TMPTATLGNLRGYGMASPGLAA---PSLTPPQLATPNL 147
+ +MPP + + TMP L + P L A P PP + P+L
Sbjct: 510 YMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSL 569
Query: 148 QQFFP---QATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMP 204
P S GPPPV + P + +G P + SST P +P
Sbjct: 570 PTSVPPPGMPPSLSSAGPPPV---LPPPSLSSAGPPPVLPPPSLSSTAP----PPVMPLP 622
Query: 205 VEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRS 264
+ PP G P+ P+ P P ++ + P +P P + LP
Sbjct: 623 PLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVP-EKPRP---ALLPTPVSFG 678
Query: 265 SEEPTEKEPPGQ 276
S PT PP Q
Sbjct: 679 SAPPTTYHPPLQ 690
Score = 35.4 bits (80), Expect = 0.22
Identities = 29/120 (24%), Positives = 43/120 (35%), Gaps = 10/120 (8%)
Query: 283 PQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQ 342
P ++M P T P +LP +L V+P P + P +P T V P
Sbjct: 522 PYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLP---TSVPPPGM 578
Query: 343 KQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPP 402
+ + P ++ P L P P + + A P V P PP + PP
Sbjct: 579 PPSLSSAGPPPVL-----PPPSLSSAGPPPVLPPPSLSSTAPPPVMPL--PPLSSATPPP 631
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 61.6 bits (148), Expect = 3e-09
Identities = 45/98 (45%), Positives = 50/98 (51%), Gaps = 6/98 (6%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQLQ-----QQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRG 58
QQQQQQ QQQQQQ QQ QQQQ Q QQQ QQQ + QQ QQ Q +
Sbjct: 599 QQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQ 658
Query: 59 LPPQQPQQPLLNLQGTNSASLLNGSM-LQRALLLQQLQ 95
QQ Q Q S LL + LQ+ LLLQQ+Q
Sbjct: 659 QQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQ 696
Score = 57.8 bits (138), Expect = 4e-08
Identities = 109/503 (21%), Positives = 180/503 (35%), Gaps = 107/503 (21%)
Query: 129 SPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTS 188
SPGL PQL P+ F A P VP + +Q PQ + S
Sbjct: 369 SPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQ-------PQTGSGAS 421
Query: 189 SSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPE 248
+ ++ S +Q + + RM + Q P + + + P
Sbjct: 422 RALPSWQEVSHAQQLK-------QIAANRQQHARMQQHQQQHQPT---NWSALPSSAGPS 471
Query: 249 PEPCEASELPAKRL-------RSSEEPTEKEPPGQLQV------KAQPQAR---MTVPKQ 292
P P ++P+ +SS P GQ +V KA P A+ + V Q
Sbjct: 472 PGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQ 531
Query: 293 TQTPDLLPEALEAQVLPRFQPRV---------------LQVQAQVQSQTQPRIPSTDTQV 337
Q P L + P +PR Q+ + + SQ +P + Q
Sbjct: 532 -QKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQ 590
Query: 338 QPKLQKQAQTQTSPEHLVLQQKQVQPQLQQE----AEPQKQVQPQVHTQAQPSVQPQEHP 393
Q + Q+Q Q Q + QQ+Q Q Q QQ+ A+ Q+Q Q + Q Q Q Q+
Sbjct: 591 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQ 650
Query: 394 PAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPV 453
Q Q +Q +QP +QP SL P Q P++ P P+
Sbjct: 651 QQQQQQQQQQQQQQQPSSQPAQSL--PSQ-PLL---------------------RSPLPL 686
Query: 454 GTQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPV 513
++ ++++QN+ G+ + + ++ V G P
Sbjct: 687 QQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTG--------------------PS 726
Query: 514 PRPSDSVSSTPAATSTPSKQALQFFCYICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQ 573
P P+ + + S+Q+L + + +Q Q + E Q QQ L + Q ++
Sbjct: 727 PSPNPCSNPNTGSGYMNSQQSL-----LNQQLMGKKQTLQRQIME-QKQQLLLQQQMLAD 780
Query: 574 ACLLSLLPVPRDVLETEDEEPPP 596
A ++ P+D + PPP
Sbjct: 781 AEKIA----PQDQINRHLSRPPP 799
Score = 52.0 bits (123), Expect = 2e-06
Identities = 32/66 (48%), Positives = 38/66 (57%), Gaps = 1/66 (1%)
Query: 6 QQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQ 65
QQQQ QQQQQQ QQ QQQQ QQQQ QQ Q L Q ++PLP+ + L Q
Sbjct: 639 QQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQ-QKLLLQQMQN 697
Query: 66 QPLLNL 71
QP+ +
Sbjct: 698 QPIAGM 703
Score = 41.6 bits (96), Expect = 0.003
Identities = 35/107 (32%), Positives = 41/107 (38%), Gaps = 6/107 (5%)
Query: 3 SQQQQQQL------QQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVS 56
S Q QQ+ Q + L QQQQ QQQQ QQQQ Q QQ QQ Q S
Sbjct: 564 SDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSS 623
Query: 57 RGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMP 103
QQ QQ ++ Q Q+ QQ Q + P
Sbjct: 624 ISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQP 670
Score = 39.3 bits (90), Expect = 0.015
Identities = 42/112 (37%), Positives = 54/112 (48%), Gaps = 23/112 (20%)
Query: 4 QQQQQQLQQQQ----QQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGL 59
QQQQQQ QQQQ Q Q L Q L + L QQ L LQQ+ Q+ P A + VS
Sbjct: 654 QQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQM--QNQPIAGMGYQVS--- 708
Query: 60 PPQQPQQPLLNLQGTNSA-----------SLLNGSM-LQRALLLQQLQGLDQ 99
QQ +Q ++ G N+ + +G M Q++LL QQL G Q
Sbjct: 709 --QQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQ 758
Score = 36.2 bits (82), Expect = 0.13
Identities = 73/335 (21%), Positives = 120/335 (35%), Gaps = 42/335 (12%)
Query: 1 MFSQQQ--QQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRG 58
M SQQ QQL ++Q LQ+ +Q QQ LQQQ L +++ PQ + +SR
Sbjct: 742 MNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKI----APQDQINRHLSRP 797
Query: 59 LPPQQPQ-------QPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAG 111
P + Q QP G +S LN + + ++ ++ T
Sbjct: 798 PPDYKDQRRNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSSLLSTSHGTRM 857
Query: 112 LTMPTATLGNLRGYG---MASPGLAAPSLTPPQLATP-NLQQFFPQATRQSLLGPPPVGV 167
++ TA + N+ YG P + + QL N +Q + PP +G
Sbjct: 858 PSLSTA-VQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQNNPMMPRPPTLGP 916
Query: 168 PMNPSQFNLS----GRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRM 223
N + G + Q + + S +S M + + P S+E +
Sbjct: 917 SNNNNVATFGAGSVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQ 976
Query: 224 DTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSE-EPTEKEPPGQL----Q 278
+ + R P P ++ + + S + PP QL Q
Sbjct: 977 EALTSAGV-----------RFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPAVQ 1025
Query: 279 VKAQPQARMTVPKQTQTP----DLLPEALEAQVLP 309
++ Q T+ QT P +L P L Q+LP
Sbjct: 1026 MRPMNQMSQTLNGQTMGPLRGLNLRPNQLSTQILP 1060
Score = 33.1 bits (74), Expect = 1.1
Identities = 77/416 (18%), Positives = 150/416 (36%), Gaps = 61/416 (14%)
Query: 6 QQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQ 65
Q+ QQ +Q+ +QQ + QQ QQQ L S +P P + P Q
Sbjct: 428 QEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQ 487
Query: 66 Q-------PLLNLQGTNSASLLNGSMLQRALLLQQLQGLD-QFAMPPATYDTAGLTMPTA 117
Q P+ + G + S + + + +A Q LD P + + P
Sbjct: 488 QTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNP-- 545
Query: 118 TLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLS 177
P++ P Q T L F Q + P + PS + +
Sbjct: 546 ----------------HPAMEPRQGNTKPLFHFNSDQANQQM--PSVLPSQNKPSLLHYT 587
Query: 178 GRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPED 237
+ Q+Q + ++ Q + + S + + + +
Sbjct: 588 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSS------------ 635
Query: 238 IAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPD 297
I+ +++ + + + + ++ + ++P+ + P Q + +QP R +P Q +
Sbjct: 636 ISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQ--PAQ-SLPSQPLLRSPLPLQQK--- 689
Query: 298 LLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQ 357
LL + ++ Q + +V +Q Q Q Q + +T P + T ++ Q
Sbjct: 690 LLLQQMQNQPIAGMGYQV----SQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQ 745
Query: 358 QKQVQPQ-------LQQEAEPQKQ---VQPQVHTQAQPSVQPQEHPPAQVSVQPPE 403
Q + Q LQ++ QKQ +Q Q+ A+ + PQ+ +S PP+
Sbjct: 746 QSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAE-KIAPQDQINRHLSRPPPD 800
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,446,231
Number of Sequences: 37866
Number of extensions: 2417869
Number of successful extensions: 45849
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 538
Number of HSP's successfully gapped in prelim test: 1066
Number of HSP's that attempted gapping in prelim test: 19855
Number of HSP's gapped (non-prelim): 13371
length of query: 842
length of database: 18,247,518
effective HSP length: 111
effective length of query: 731
effective length of database: 14,044,392
effective search space: 10266450552
effective search space used: 10266450552
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.