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Search of human proteins with 194018518
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194018518 synaptoporin isoform 1 [Homo sapiens]
(285 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194018518 synaptoporin isoform 1 [Homo sapiens] 575 e-164
gi|21389481 synaptoporin isoform 2 [Homo sapiens] 523 e-149
gi|27764867 synaptophysin [Homo sapiens] 340 1e-93
gi|105554421 mitsugumin 29 [Homo sapiens] 237 8e-63
gi|33239443 synaptophysin-like 1 isoform b [Homo sapiens] 201 5e-52
gi|5803185 synaptophysin-like 1 isoform a [Homo sapiens] 201 5e-52
gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo s... 39 0.007
gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo s... 39 0.007
gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo s... 39 0.007
gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo s... 39 0.007
gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo sap... 39 0.007
gi|22035696 synaptogyrin 1 isoform 1a [Homo sapiens] 35 0.058
gi|5032099 smoothened [Homo sapiens] 35 0.075
gi|4759202 synaptogyrin 2 [Homo sapiens] 35 0.098
gi|56682966 transforming growth factor, beta receptor III [Homo ... 33 0.22
gi|62122917 filaggrin family member 2 [Homo sapiens] 33 0.37
gi|34734079 frizzled 6 [Homo sapiens] 32 0.64
gi|66932929 myeloid-associated differentiation marker [Homo sapi... 32 0.64
gi|66932927 myeloid-associated differentiation marker [Homo sapi... 32 0.64
gi|66932925 myeloid-associated differentiation marker [Homo sapi... 32 0.64
gi|66932923 myeloid-associated differentiation marker [Homo sapi... 32 0.64
gi|19923903 myeloid-associated differentiation marker [Homo sapi... 32 0.64
gi|22035700 synaptogyrin 1 isoform 1c [Homo sapiens] 32 0.64
gi|22035698 synaptogyrin 1 isoform 1b [Homo sapiens] 32 0.64
gi|11321597 kinase insert domain receptor precursor [Homo sapiens] 32 0.83
gi|57864582 hornerin [Homo sapiens] 31 1.1
gi|6631112 synaptogyrin 3 [Homo sapiens] 31 1.1
gi|27262624 ATP-binding cassette, sub-family A , member 5 [Homo ... 30 1.9
gi|27262626 ATP-binding cassette, sub-family A , member 5 [Homo ... 30 1.9
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 30 2.4
>gi|194018518 synaptoporin isoform 1 [Homo sapiens]
Length = 285
Score = 575 bits (1481), Expect = e-164
Identities = 285/285 (100%), Positives = 285/285 (100%)
Query: 1 MDPVSQLASAGTFRVLKEPLAFLRALELLFAIFAFATCGGYSGGLRLSVDCVNKTESNLS 60
MDPVSQLASAGTFRVLKEPLAFLRALELLFAIFAFATCGGYSGGLRLSVDCVNKTESNLS
Sbjct: 1 MDPVSQLASAGTFRVLKEPLAFLRALELLFAIFAFATCGGYSGGLRLSVDCVNKTESNLS 60
Query: 61 IDIAFAYPFRLHQVTFEVPTCEGKERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVY 120
IDIAFAYPFRLHQVTFEVPTCEGKERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVY
Sbjct: 61 IDIAFAYPFRLHQVTFEVPTCEGKERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVY 120
Query: 121 IFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQ 180
IFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQ
Sbjct: 121 IFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQ 180
Query: 181 PSNKCMAIHSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRYLSDPMEKHSS 240
PSNKCMAIHSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRYLSDPMEKHSS
Sbjct: 181 PSNKCMAIHSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRYLSDPMEKHSS 240
Query: 241 SYNQGGYNQDSYGSSSGYSQQASLGPTSDEFGQQPTGPTSFTNQI 285
SYNQGGYNQDSYGSSSGYSQQASLGPTSDEFGQQPTGPTSFTNQI
Sbjct: 241 SYNQGGYNQDSYGSSSGYSQQASLGPTSDEFGQQPTGPTSFTNQI 285
>gi|21389481 synaptoporin isoform 2 [Homo sapiens]
Length = 265
Score = 523 bits (1347), Expect = e-149
Identities = 257/257 (100%), Positives = 257/257 (100%)
Query: 29 LFAIFAFATCGGYSGGLRLSVDCVNKTESNLSIDIAFAYPFRLHQVTFEVPTCEGKERQK 88
LFAIFAFATCGGYSGGLRLSVDCVNKTESNLSIDIAFAYPFRLHQVTFEVPTCEGKERQK
Sbjct: 9 LFAIFAFATCGGYSGGLRLSVDCVNKTESNLSIDIAFAYPFRLHQVTFEVPTCEGKERQK 68
Query: 89 LALIGDSSSSAEFFVTVAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSFLW 148
LALIGDSSSSAEFFVTVAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSFLW
Sbjct: 69 LALIGDSSSSAEFFVTVAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSFLW 128
Query: 149 LVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPSNKCMAIHSPVMSSLNTSVVFGFLNFI 208
LVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPSNKCMAIHSPVMSSLNTSVVFGFLNFI
Sbjct: 129 LVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPSNKCMAIHSPVMSSLNTSVVFGFLNFI 188
Query: 209 LWAGNIWFVFKETGWHSSGQRYLSDPMEKHSSSYNQGGYNQDSYGSSSGYSQQASLGPTS 268
LWAGNIWFVFKETGWHSSGQRYLSDPMEKHSSSYNQGGYNQDSYGSSSGYSQQASLGPTS
Sbjct: 189 LWAGNIWFVFKETGWHSSGQRYLSDPMEKHSSSYNQGGYNQDSYGSSSGYSQQASLGPTS 248
Query: 269 DEFGQQPTGPTSFTNQI 285
DEFGQQPTGPTSFTNQI
Sbjct: 249 DEFGQQPTGPTSFTNQI 265
>gi|27764867 synaptophysin [Homo sapiens]
Length = 313
Score = 340 bits (871), Expect = 1e-93
Identities = 176/309 (56%), Positives = 211/309 (68%), Gaps = 26/309 (8%)
Query: 1 MDPVSQLASAGTFRVLKEPLAFLRALELLFAIFAFATCGGYSGGLRLSVDCVNKTESNLS 60
MD V+QL + G FRV+KEPL F++ L+ +FAIFAFATCG YSG L+LSVDC NKTES+LS
Sbjct: 7 MDVVNQLVAGGQFRVVKEPLGFVKVLQWVFAIFAFATCGSYSGELQLSVDCANKTESDLS 66
Query: 61 IDIAFAYPFRLHQVTFEVPTCEGKERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVY 120
I++ F YPFRLHQV F+ PTC G K+ L+GD SSSAEFFVTVAVFAFLYS+ A Y
Sbjct: 67 IEVEFEYPFRLHQVYFDAPTCRGGTT-KVFLVGDYSSSAEFFVTVAVFAFLYSMGALATY 125
Query: 121 IFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQ 180
IF QNKYRENN+GP++DF+ T VF+F+WLV SSAWAKGLSDVK+ATDP+ ++ M C+Q
Sbjct: 126 IFLQNKYRENNKGPMLDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENIIKEMPVCRQ 185
Query: 181 PSNKCMAIHSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRYLSDPMEKH-- 238
N C + PV S LNTSVVFGFLN +LW GN+WFVFKETGW + R EK
Sbjct: 186 TGNTCKELRDPVTSGLNTSVVFGFLNLVLWVGNLWFVFKETGWAAPFLRAPPGAPEKQPA 245
Query: 239 -SSSYNQGGYN--------QDSYGSSSGY---------SQQASLGPTSDEFGQQPTG--- 277
+Y GY QDSYG GY S + GP D +GQQ G
Sbjct: 246 PGDAYGDAGYGQGPGGYGPQDSYGPQGGYQPDYGQPAGSGGSGYGPQGD-YGQQGYGPQG 304
Query: 278 -PTSFTNQI 285
PTSF+NQ+
Sbjct: 305 APTSFSNQM 313
>gi|105554421 mitsugumin 29 [Homo sapiens]
Length = 272
Score = 237 bits (605), Expect = 8e-63
Identities = 115/226 (50%), Positives = 150/226 (66%), Gaps = 1/226 (0%)
Query: 4 VSQLASAGTFRVLKEPLAFLRALELLFAIFAFATCGGYSGGLRLSVDCVNKTESNLSIDI 63
V +L +R L+EPL F++ L+ LFAIFAF +CG YSG V C N+ + SI +
Sbjct: 19 VDRLLVGLRWRRLEEPLGFIKVLQWLFAIFAFGSCGSYSGETGAMVRCNNEAKDVSSIIV 78
Query: 64 AFAYPFRLHQVTFEVPTCEGKERQK-LALIGDSSSSAEFFVTVAVFAFLYSLAATVVYIF 122
AF YPFRLH++ +E+P C+ + K + L+GD S+ AEFFVT+ +F+F Y++AA V+Y+
Sbjct: 79 AFGYPFRLHRIQYEMPLCDEESSSKTMHLMGDFSAPAEFFVTLGIFSFFYTMAALVIYLR 138
Query: 123 FQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPS 182
F N Y EN R PL+DF VTV F+F WLV ++AW KGL+DVK AT P + MS C
Sbjct: 139 FHNLYTENKRFPLVDFCVTVSFTFFWLVAAAAWGKGLTDVKGATRPSSLTAAMSVCHGEE 198
Query: 183 NKCMAIHSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQ 228
C A +P M N SV+FGF+NF LWAGN WFVFKET WH GQ
Sbjct: 199 AVCSAGATPSMGLANISVLFGFINFFLWAGNCWFVFKETPWHGQGQ 244
>gi|33239443 synaptophysin-like 1 isoform b [Homo sapiens]
Length = 241
Score = 201 bits (512), Expect = 5e-52
Identities = 104/235 (44%), Positives = 149/235 (63%), Gaps = 15/235 (6%)
Query: 16 LKEPLAFLRALELLFAIFAFATCGGYSGGLRLSVDCVNKTESNLSIDIAFAYPFRLHQVT 75
LKEPL F++ LE + +IFAFATCGG+ G + V+C N ++ F YPFRL++ +
Sbjct: 11 LKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATFGYPFRLNEAS 70
Query: 76 FEVPT----CEGKERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVYIFFQNKYRENN 131
F+ P C+ + + LIGD SSSA+F+VT AVF FLY +AA ++Y+ + + Y ++
Sbjct: 71 FQPPPGVNICDVNWKDYV-LIGDYSSSAQFYVTFAVFVFLYCIAALLLYVGYTSLYLDSR 129
Query: 132 RGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPSNKCMAIHSP 191
+ P+IDF+VT+V +FLWLV +SAWAK L+D+K+AT ++ + CK+ + C
Sbjct: 130 KLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATG-HNIIDELPPCKKKAVLCYFGSVT 188
Query: 192 VMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRYLSDPMEKHSSSYNQGG 246
M SLN SV+FGFLN ILW GN WFV+KET HS S+ ++QGG
Sbjct: 189 SMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNT---------SAPHSQGG 234
>gi|5803185 synaptophysin-like 1 isoform a [Homo sapiens]
Length = 259
Score = 201 bits (512), Expect = 5e-52
Identities = 104/235 (44%), Positives = 149/235 (63%), Gaps = 15/235 (6%)
Query: 16 LKEPLAFLRALELLFAIFAFATCGGYSGGLRLSVDCVNKTESNLSIDIAFAYPFRLHQVT 75
LKEPL F++ LE + +IFAFATCGG+ G + V+C N ++ F YPFRL++ +
Sbjct: 29 LKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPAVTENKTVTATFGYPFRLNEAS 88
Query: 76 FEVPT----CEGKERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVYIFFQNKYRENN 131
F+ P C+ + + LIGD SSSA+F+VT AVF FLY +AA ++Y+ + + Y ++
Sbjct: 89 FQPPPGVNICDVNWKDYV-LIGDYSSSAQFYVTFAVFVFLYCIAALLLYVGYTSLYLDSR 147
Query: 132 RGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPSNKCMAIHSP 191
+ P+IDF+VT+V +FLWLV +SAWAK L+D+K+AT ++ + CK+ + C
Sbjct: 148 KLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATG-HNIIDELPPCKKKAVLCYFGSVT 206
Query: 192 VMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRYLSDPMEKHSSSYNQGG 246
M SLN SV+FGFLN ILW GN WFV+KET HS S+ ++QGG
Sbjct: 207 SMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNT---------SAPHSQGG 252
>gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo
sapiens]
Length = 354
Score = 38.5 bits (88), Expect = 0.007
Identities = 22/46 (47%), Positives = 30/46 (65%), Gaps = 4/46 (8%)
Query: 240 SSYNQGGYNQ-DSYGSSSGYSQQASLGPTSDEFGQQPTGPTSFTNQ 284
+SY+Q Y+Q ++YG S Y QQ+S G S +GQQP PTS+ Q
Sbjct: 201 TSYDQSSYSQQNTYGQPSSYGQQSSYGQQS-SYGQQP--PTSYPPQ 243
>gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo
sapiens]
Length = 600
Score = 38.5 bits (88), Expect = 0.007
Identities = 22/46 (47%), Positives = 30/46 (65%), Gaps = 4/46 (8%)
Query: 240 SSYNQGGYNQ-DSYGSSSGYSQQASLGPTSDEFGQQPTGPTSFTNQ 284
+SY+Q Y+Q ++YG S Y QQ+S G S +GQQP PTS+ Q
Sbjct: 145 TSYDQSSYSQQNTYGQPSSYGQQSSYGQQS-SYGQQP--PTSYPPQ 187
>gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo
sapiens]
Length = 655
Score = 38.5 bits (88), Expect = 0.007
Identities = 22/46 (47%), Positives = 30/46 (65%), Gaps = 4/46 (8%)
Query: 240 SSYNQGGYNQ-DSYGSSSGYSQQASLGPTSDEFGQQPTGPTSFTNQ 284
+SY+Q Y+Q ++YG S Y QQ+S G S +GQQP PTS+ Q
Sbjct: 201 TSYDQSSYSQQNTYGQPSSYGQQSSYGQQS-SYGQQP--PTSYPPQ 243
>gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo
sapiens]
Length = 661
Score = 38.5 bits (88), Expect = 0.007
Identities = 22/46 (47%), Positives = 30/46 (65%), Gaps = 4/46 (8%)
Query: 240 SSYNQGGYNQ-DSYGSSSGYSQQASLGPTSDEFGQQPTGPTSFTNQ 284
+SY+Q Y+Q ++YG S Y QQ+S G S +GQQP PTS+ Q
Sbjct: 207 TSYDQSSYSQQNTYGQPSSYGQQSSYGQQS-SYGQQP--PTSYPPQ 249
>gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo
sapiens]
Length = 656
Score = 38.5 bits (88), Expect = 0.007
Identities = 22/46 (47%), Positives = 30/46 (65%), Gaps = 4/46 (8%)
Query: 240 SSYNQGGYNQ-DSYGSSSGYSQQASLGPTSDEFGQQPTGPTSFTNQ 284
+SY+Q Y+Q ++YG S Y QQ+S G S +GQQP PTS+ Q
Sbjct: 201 TSYDQSSYSQQNTYGQPSSYGQQSSYGQQS-SYGQQP--PTSYPPQ 243
>gi|22035696 synaptogyrin 1 isoform 1a [Homo sapiens]
Length = 233
Score = 35.4 bits (80), Expect = 0.058
Identities = 42/200 (21%), Positives = 74/200 (37%), Gaps = 28/200 (14%)
Query: 85 ERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVYIFFQ--NKYRENNRGPLIDFIVTV 142
E ++ + + ++ + V V V AFL L + ++F + ++ + L D V+
Sbjct: 54 EGEEFCIYNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSA 113
Query: 143 VFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPSNKCMAIHSPVMSSLNTSVVF 202
++FLW VG L++ + PK+ P N+ + ++ F
Sbjct: 114 FWAFLWFVGFCY----LANQWQVSKPKD---------NPLNE-------GTDAARAAIAF 153
Query: 203 GFLNFILWAGNIWFVFKETGWHSSGQRYLSDPME-KHSSSYNQGGY----NQDSYGSSSG 257
F + WAG F+ + + D M+ SS Y D G
Sbjct: 154 SFFSIFTWAGQAVLAFQRYQIGADSALFSQDYMDPSQDSSMPYAPYVEPTGPDPAGMGGT 213
Query: 258 YSQQASLGPTSDEFGQQPTG 277
Y Q A+ T + G Q G
Sbjct: 214 YQQPANTFDTEPQ-GYQSQG 232
>gi|5032099 smoothened [Homo sapiens]
Length = 787
Score = 35.0 bits (79), Expect = 0.075
Identities = 32/124 (25%), Positives = 53/124 (42%), Gaps = 17/124 (13%)
Query: 105 VAVFAFLYSLAATVVYIFFQNKYRENNRGP-LIDFIVTVVFSFLWLVGSSAWAKGLSDVK 163
+A F + L F +R +NR P +I F V F VGS W D
Sbjct: 234 IAAFGAVTGLCTLFTLATFVADWRNSNRYPAVILFYVNACF----FVGSIGWLAQFMDGA 289
Query: 164 VATDPKEVLLLMSACKQPSNKCMAIHSPVMS-SLNTSVVFGFLNFILWAGNIWFVFKETG 222
+E++ C+ ++ M + P + +L+ ++F + + L AG +WFV
Sbjct: 290 ----RREIV-----CR--ADGTMRLGEPTSNETLSCVIIFVIVYYALMAGVVWFVVLTYA 338
Query: 223 WHSS 226
WH+S
Sbjct: 339 WHTS 342
>gi|4759202 synaptogyrin 2 [Homo sapiens]
Length = 224
Score = 34.7 bits (78), Expect = 0.098
Identities = 34/177 (19%), Positives = 70/177 (39%), Gaps = 34/177 (19%)
Query: 84 KERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVYIFFQNKYRENNRGPLI--DFIVT 141
+ +Q + + + + + V AFL S VV +F +R L+ D + +
Sbjct: 53 ESKQMYCVFNRNEDACRYGSAIGVLAFLASAFFLVVDAYFPQISNATDRKYLVIGDLLFS 112
Query: 142 VVFSFLWLVG----SSAWAKGLSDVKVATDPKEVLLLMSACKQPSNKCMAIHSPVMSSLN 197
+++FLW VG ++ WA T+PK+VL+ S+
Sbjct: 113 ALWTFLWFVGFCFLTNQWA--------VTNPKDVLV------------------GADSVR 146
Query: 198 TSVVFGFLNFILWA--GNIWFVFKETGWHSSGQRYLSDPMEKHSSSYNQGGYNQDSY 252
++ F F + W ++ + + G Q Y+ + +++ + G + D+Y
Sbjct: 147 AAITFSFFSIFSWGVLASLAYQRYKAGVDDFIQNYVDPTPDPNTAYASYPGASVDNY 203
>gi|56682966 transforming growth factor, beta receptor III [Homo
sapiens]
Length = 851
Score = 33.5 bits (75), Expect = 0.22
Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 10/117 (8%)
Query: 149 LVGSSAWAKGLSDVKVATDPKEVLLLMSACKQ--PSNK-CMAIHSPVMSSLNTSVVFG-- 203
L S WA + + K T P V+ + K+ PS K I P+ L+T V G
Sbjct: 733 LDASIIWAM-MQNKKTFTKPLAVIHHEAESKEKGPSMKEPNPISPPIFHGLDTLTVMGIA 791
Query: 204 FLNFILWA---GNIWFVFKETGWHSSGQRY-LSDPMEKHSSSYNQGGYNQDSYGSSS 256
F F++ A G +W+++ TG + Q+ S P ++SS+ + G Q + SSS
Sbjct: 792 FAAFVIGALLTGALWYIYSHTGETAGRQQVPTSPPASENSSAAHSIGSTQSTPCSSS 848
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 32.7 bits (73), Expect = 0.37
Identities = 22/63 (34%), Positives = 27/63 (42%), Gaps = 2/63 (3%)
Query: 222 GWHSSGQRYLSDPMEKHSSSYNQGGYNQ--DSYGSSSGYSQQASLGPTSDEFGQQPTGPT 279
G H SG S + SSS G+ Q S G SG+ Q S S FGQ TG
Sbjct: 846 GQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSG 905
Query: 280 SFT 282
++
Sbjct: 906 QYS 908
Score = 32.0 bits (71), Expect = 0.64
Identities = 22/58 (37%), Positives = 25/58 (43%), Gaps = 2/58 (3%)
Query: 222 GWHSSGQRYLSDPMEKHSSSYNQGGYNQ--DSYGSSSGYSQQASLGPTSDEFGQQPTG 277
G H SG S + SSS G+ Q S G SG+ Q S S FGQ TG
Sbjct: 1000 GQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTG 1057
Score = 31.6 bits (70), Expect = 0.83
Identities = 24/63 (38%), Positives = 28/63 (44%), Gaps = 5/63 (7%)
Query: 222 GWHSSGQRYLSDPMEKHSSSYNQGGYNQDSYGS--SSGYSQQASLGPTSDEFGQQPTGPT 279
G H SG S +H S Q Y Q S GS SSGY Q S + FGQ +G +
Sbjct: 594 GQHGSGSGQ-SSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGS--RQTSGFGQHGSGSS 650
Query: 280 SFT 282
T
Sbjct: 651 QST 653
Score = 31.6 bits (70), Expect = 0.83
Identities = 24/63 (38%), Positives = 28/63 (44%), Gaps = 5/63 (7%)
Query: 222 GWHSSGQRYLSDPMEKHSSSYNQGGYNQDSYGS--SSGYSQQASLGPTSDEFGQQPTGPT 279
G H SG S +H S Q Y Q S GS SSGY Q S + FGQ +G +
Sbjct: 746 GQHGSGSGQ-SSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGS--RQTSGFGQHGSGSS 802
Query: 280 SFT 282
T
Sbjct: 803 QST 805
Score = 31.6 bits (70), Expect = 0.83
Identities = 22/58 (37%), Positives = 26/58 (44%), Gaps = 2/58 (3%)
Query: 222 GWHSSGQRYLSDPMEKHSSSYNQGGYNQDSYGS--SSGYSQQASLGPTSDEFGQQPTG 277
G H SG S + SSS G+ Q GS SSG+ Q S S FGQ +G
Sbjct: 923 GQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESG 980
Score = 30.8 bits (68), Expect = 1.4
Identities = 21/54 (38%), Positives = 24/54 (44%), Gaps = 3/54 (5%)
Query: 222 GWHSSGQRYLSDPMEKHSSSYNQGGYNQDSYGSS--SGYSQQASLGPTSDEFGQ 273
G H SG S +H S +Q Y Q GSS SGY Q S + FGQ
Sbjct: 975 GQHESGSGK-SSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQ 1027
Score = 30.4 bits (67), Expect = 1.9
Identities = 20/54 (37%), Positives = 23/54 (42%), Gaps = 3/54 (5%)
Query: 222 GWHSSGQRYLSDPMEKHSSSYNQGGYNQDSYGSS--SGYSQQASLGPTSDEFGQ 273
G H SG S +H S Y Q +GSS SGY Q S + FGQ
Sbjct: 669 GQHVSGSGQ-SSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQ 721
Score = 30.4 bits (67), Expect = 1.9
Identities = 21/58 (36%), Positives = 26/58 (44%), Gaps = 2/58 (3%)
Query: 222 GWHSSGQRYLSDPMEKHSSSYNQGGYNQDSYGS--SSGYSQQASLGPTSDEFGQQPTG 277
G H SG S + S+S G+ Q GS SSG+ Q S S FGQ +G
Sbjct: 1077 GQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSG 1134
Score = 28.9 bits (63), Expect = 5.4
Identities = 21/64 (32%), Positives = 27/64 (42%), Gaps = 3/64 (4%)
Query: 222 GWHSSGQRYLSDPMEKHSSSYNQGGYNQDSYGSS--SGYSQQASLGPTSDEFGQQPTGPT 279
G H SG S +H Q Y Q GSS SG Q S + FGQ +G
Sbjct: 1129 GQHGSGTGK-SSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSD 1187
Query: 280 SFTN 283
+F++
Sbjct: 1188 NFSS 1191
Score = 28.5 bits (62), Expect = 7.0
Identities = 19/54 (35%), Positives = 23/54 (42%), Gaps = 2/54 (3%)
Query: 222 GWHSSGQRYLSDPMEKHSSSYNQGGYNQDSY--GSSSGYSQQASLGPTSDEFGQ 273
G H SG S + S S G+ Q G SSG+ Q S+ S FGQ
Sbjct: 480 GQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQ 533
Score = 28.1 bits (61), Expect = 9.2
Identities = 16/42 (38%), Positives = 21/42 (50%), Gaps = 1/42 (2%)
Query: 237 KHSSSYNQ-GGYNQDSYGSSSGYSQQASLGPTSDEFGQQPTG 277
+HSS +Q GY Q +SG+ Q S S FGQ +G
Sbjct: 620 QHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSG 661
Score = 28.1 bits (61), Expect = 9.2
Identities = 16/42 (38%), Positives = 21/42 (50%), Gaps = 1/42 (2%)
Query: 237 KHSSSYNQ-GGYNQDSYGSSSGYSQQASLGPTSDEFGQQPTG 277
+HSS +Q GY Q +SG+ Q S S FGQ +G
Sbjct: 772 QHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSG 813
>gi|34734079 frizzled 6 [Homo sapiens]
Length = 706
Score = 32.0 bits (71), Expect = 0.64
Identities = 31/145 (21%), Positives = 63/145 (43%), Gaps = 31/145 (21%)
Query: 101 FFVTVAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDF-----IVTVVFSFLWLVGSSAW 155
F TV++F +L + ++ ++R R P+I + IV++++ +L+G S
Sbjct: 201 FIGTVSIFCLCATLFTFLTFLIDVRRFRYPER-PIIYYSVCYSIVSLMYFIGFLLGDS-- 257
Query: 156 AKGLSDVKVATDPKEVLLLMSACKQPSNKCMAIHSPVMSSLNTS--VVFGFLNFILWAGN 213
+AC + K + V+ S N + V+F L F AG
Sbjct: 258 --------------------TACNKADEKLELGDTVVLGSQNKACTVLFMLLYFFTMAGT 297
Query: 214 IWFVFKETGWH-SSGQRYLSDPMEK 237
+W+V W ++G+++ + +E+
Sbjct: 298 VWWVILTITWFLAAGRKWSCEAIEQ 322
>gi|66932929 myeloid-associated differentiation marker [Homo
sapiens]
Length = 322
Score = 32.0 bits (71), Expect = 0.64
Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 22/113 (19%)
Query: 11 GTFRVLKEPLAFLRALELLFAIFAF---ATCGGYSGGLRLSVDCVNKTESNLSIDIAFAY 67
G+ R L +PL LR L+L+ AF A+ G ++G + N S+ + +
Sbjct: 27 GSPRALTQPLGLLRLLQLVSTCVAFSLVASVGAWTGSM-----------GNWSM-FTWCF 74
Query: 68 PFRLHQVTFEVPTCEGKERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVY 120
F + + V C + R L S F +T A +A L+ L+A+++Y
Sbjct: 75 CFSVTLIILIVELCGLQARFPL-------SWRNFPITFACYAALFCLSASIIY 120
>gi|66932927 myeloid-associated differentiation marker [Homo
sapiens]
Length = 322
Score = 32.0 bits (71), Expect = 0.64
Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 22/113 (19%)
Query: 11 GTFRVLKEPLAFLRALELLFAIFAF---ATCGGYSGGLRLSVDCVNKTESNLSIDIAFAY 67
G+ R L +PL LR L+L+ AF A+ G ++G + N S+ + +
Sbjct: 27 GSPRALTQPLGLLRLLQLVSTCVAFSLVASVGAWTGSM-----------GNWSM-FTWCF 74
Query: 68 PFRLHQVTFEVPTCEGKERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVY 120
F + + V C + R L S F +T A +A L+ L+A+++Y
Sbjct: 75 CFSVTLIILIVELCGLQARFPL-------SWRNFPITFACYAALFCLSASIIY 120
>gi|66932925 myeloid-associated differentiation marker [Homo
sapiens]
Length = 322
Score = 32.0 bits (71), Expect = 0.64
Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 22/113 (19%)
Query: 11 GTFRVLKEPLAFLRALELLFAIFAF---ATCGGYSGGLRLSVDCVNKTESNLSIDIAFAY 67
G+ R L +PL LR L+L+ AF A+ G ++G + N S+ + +
Sbjct: 27 GSPRALTQPLGLLRLLQLVSTCVAFSLVASVGAWTGSM-----------GNWSM-FTWCF 74
Query: 68 PFRLHQVTFEVPTCEGKERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVY 120
F + + V C + R L S F +T A +A L+ L+A+++Y
Sbjct: 75 CFSVTLIILIVELCGLQARFPL-------SWRNFPITFACYAALFCLSASIIY 120
>gi|66932923 myeloid-associated differentiation marker [Homo
sapiens]
Length = 322
Score = 32.0 bits (71), Expect = 0.64
Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 22/113 (19%)
Query: 11 GTFRVLKEPLAFLRALELLFAIFAF---ATCGGYSGGLRLSVDCVNKTESNLSIDIAFAY 67
G+ R L +PL LR L+L+ AF A+ G ++G + N S+ + +
Sbjct: 27 GSPRALTQPLGLLRLLQLVSTCVAFSLVASVGAWTGSM-----------GNWSM-FTWCF 74
Query: 68 PFRLHQVTFEVPTCEGKERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVY 120
F + + V C + R L S F +T A +A L+ L+A+++Y
Sbjct: 75 CFSVTLIILIVELCGLQARFPL-------SWRNFPITFACYAALFCLSASIIY 120
>gi|19923903 myeloid-associated differentiation marker [Homo
sapiens]
Length = 322
Score = 32.0 bits (71), Expect = 0.64
Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 22/113 (19%)
Query: 11 GTFRVLKEPLAFLRALELLFAIFAF---ATCGGYSGGLRLSVDCVNKTESNLSIDIAFAY 67
G+ R L +PL LR L+L+ AF A+ G ++G + N S+ + +
Sbjct: 27 GSPRALTQPLGLLRLLQLVSTCVAFSLVASVGAWTGSM-----------GNWSM-FTWCF 74
Query: 68 PFRLHQVTFEVPTCEGKERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVY 120
F + + V C + R L S F +T A +A L+ L+A+++Y
Sbjct: 75 CFSVTLIILIVELCGLQARFPL-------SWRNFPITFACYAALFCLSASIIY 120
>gi|22035700 synaptogyrin 1 isoform 1c [Homo sapiens]
Length = 192
Score = 32.0 bits (71), Expect = 0.64
Identities = 17/69 (24%), Positives = 34/69 (49%), Gaps = 2/69 (2%)
Query: 85 ERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVYIFFQ--NKYRENNRGPLIDFIVTV 142
E ++ + + ++ + V V V AFL L + ++F + ++ + L D V+
Sbjct: 55 EGEEFCIYNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSA 114
Query: 143 VFSFLWLVG 151
++FLW VG
Sbjct: 115 FWAFLWFVG 123
>gi|22035698 synaptogyrin 1 isoform 1b [Homo sapiens]
Length = 191
Score = 32.0 bits (71), Expect = 0.64
Identities = 17/69 (24%), Positives = 34/69 (49%), Gaps = 2/69 (2%)
Query: 85 ERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVYIFFQ--NKYRENNRGPLIDFIVTV 142
E ++ + + ++ + V V V AFL L + ++F + ++ + L D V+
Sbjct: 54 EGEEFCIYNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSA 113
Query: 143 VFSFLWLVG 151
++FLW VG
Sbjct: 114 FWAFLWFVG 122
>gi|11321597 kinase insert domain receptor precursor [Homo sapiens]
Length = 1356
Score = 31.6 bits (70), Expect = 0.83
Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 4/51 (7%)
Query: 42 SGGLRLSVDCVNKTESNLSIDIAFAYPFRLHQ----VTFEVPTCEGKERQK 88
S G +L ++C +TE N+ ID + YP HQ V ++ T G E +K
Sbjct: 237 SVGEKLVLNCTARTELNVGIDFNWEYPSSKHQHKKLVNRDLKTQSGSEMKK 287
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 31.2 bits (69), Expect = 1.1
Identities = 21/54 (38%), Positives = 24/54 (44%), Gaps = 2/54 (3%)
Query: 222 GWHSSGQRYLSDPMEKHSSSYNQGGYNQ--DSYGSSSGYSQQASLGPTSDEFGQ 273
G H SG S S S G++Q S G SSGYSQ S S +GQ
Sbjct: 206 GQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQ 259
Score = 30.4 bits (67), Expect = 1.9
Identities = 22/60 (36%), Positives = 26/60 (43%), Gaps = 7/60 (11%)
Query: 221 TGWHSSGQRYLSDPMEKHSSSYNQGGYNQDSYGSSSGYSQQASLGPTSDEFGQQPTGPTS 280
+GW SS P E SS + G+ + G SSGY Q S S GQ G TS
Sbjct: 1501 SGWSSS-----RGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQH--GSTS 1553
Score = 29.3 bits (64), Expect = 4.1
Identities = 23/61 (37%), Positives = 25/61 (40%), Gaps = 4/61 (6%)
Query: 222 GWHSSGQRYLSDPMEKHSSSYNQGGYNQDSYGS--SSGYSQQASLGPTSDEFGQQPTGPT 279
G H SG Y S S G+ Q GS SSGYS+ S S GQ G T
Sbjct: 323 GQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQH--GST 380
Query: 280 S 280
S
Sbjct: 381 S 381
Score = 29.3 bits (64), Expect = 4.1
Identities = 19/53 (35%), Positives = 20/53 (37%), Gaps = 3/53 (5%)
Query: 222 GWHSSGQRYLSDPMEKHSSSYNQGGYNQDSYGSSSGYSQQASLGPTSDEFGQQ 274
G H SG S S S G+ Q GS GYSQ G S F Q
Sbjct: 792 GQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQH---GSASGHFSSQ 841
Score = 28.9 bits (63), Expect = 5.4
Identities = 23/60 (38%), Positives = 26/60 (43%), Gaps = 7/60 (11%)
Query: 221 TGWHSSGQRYLSDPMEKHSSSYNQGGYNQDSYGSSSGYSQQASLGPTSDEFGQQPTGPTS 280
+GW SS Y S HSS G+ + G SSGY Q S S GQ G TS
Sbjct: 1031 SGWSSSRGPYESG--SGHSSGL---GHRESRSGQSSGYGQHGSSSGHSSTHGQH--GSTS 1083
Score = 28.9 bits (63), Expect = 5.4
Identities = 23/60 (38%), Positives = 26/60 (43%), Gaps = 7/60 (11%)
Query: 221 TGWHSSGQRYLSDPMEKHSSSYNQGGYNQDSYGSSSGYSQQASLGPTSDEFGQQPTGPTS 280
+GW SS Y S HSS G+ + G SSGY Q S S GQ G TS
Sbjct: 2441 SGWSSSRGPYESG--SGHSSGL---GHRESRSGQSSGYGQHGSSSGHSSTHGQH--GSTS 2493
Score = 28.5 bits (62), Expect = 7.0
Identities = 19/57 (33%), Positives = 24/57 (42%), Gaps = 2/57 (3%)
Query: 224 HSSGQRYLSDPMEKHSSSYNQGGYNQDSYGSSSGYSQQASLGPTSDEFGQQPTGPTS 280
+ SG+ P E S + G+ + G SSGY Q S S GQ G TS
Sbjct: 563 YGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQH--GSTS 617
Score = 28.5 bits (62), Expect = 7.0
Identities = 18/45 (40%), Positives = 20/45 (44%), Gaps = 2/45 (4%)
Query: 221 TGWHSSGQRYLSDPMEKHSSSYNQGGYNQDSYGS--SSGYSQQAS 263
+G H SG S SSS+ GY Q GS SS Y Q S
Sbjct: 1858 SGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGS 1902
Score = 28.5 bits (62), Expect = 7.0
Identities = 20/53 (37%), Positives = 23/53 (43%), Gaps = 5/53 (9%)
Query: 221 TGWHSSGQRYLSDPMEKHSSSYNQGGYNQDSYGSSSGYSQQASLGPTSDEFGQ 273
+GW SS Y S HSS G+ + G SSGY Q S S GQ
Sbjct: 1971 SGWSSSRGPYESG--SGHSSGL---GHRESRSGQSSGYGQHGSSSGHSSTHGQ 2018
Score = 28.5 bits (62), Expect = 7.0
Identities = 18/45 (40%), Positives = 20/45 (44%), Gaps = 2/45 (4%)
Query: 221 TGWHSSGQRYLSDPMEKHSSSYNQGGYNQDSYGS--SSGYSQQAS 263
+G H SG S SSS+ GY Q GS SS Y Q S
Sbjct: 2328 SGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGS 2372
>gi|6631112 synaptogyrin 3 [Homo sapiens]
Length = 229
Score = 31.2 bits (69), Expect = 1.1
Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
Query: 95 SSSSAEFFVTVAVFAFLYSLAATVVYIFFQ--NKYRENNRGPLIDFIVTVVFSFLWLVG 151
++ + F V + + AFL A ++ + FQ + R+ R L+D + ++SFLW VG
Sbjct: 64 NAGACRFGVALGLGAFLACAAFLLLDVRFQQISSVRDRRRAVLLDLGFSGLWSFLWFVG 122
>gi|27262624 ATP-binding cassette, sub-family A , member 5 [Homo
sapiens]
Length = 1642
Score = 30.4 bits (67), Expect = 1.9
Identities = 16/74 (21%), Positives = 35/74 (47%), Gaps = 10/74 (13%)
Query: 103 VTVAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDV 162
+ + + FLY L++ + ++++ +++F VTV F F+ GL +
Sbjct: 297 IVIFLLFFLYGLSSVFFALMLTPLFKKSKHVGIVEFFVTVAFGFI----------GLMII 346
Query: 163 KVATDPKEVLLLMS 176
+ + PK ++ L S
Sbjct: 347 LIESFPKSLVWLFS 360
>gi|27262626 ATP-binding cassette, sub-family A , member 5 [Homo
sapiens]
Length = 1642
Score = 30.4 bits (67), Expect = 1.9
Identities = 16/74 (21%), Positives = 35/74 (47%), Gaps = 10/74 (13%)
Query: 103 VTVAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDV 162
+ + + FLY L++ + ++++ +++F VTV F F+ GL +
Sbjct: 297 IVIFLLFFLYGLSSVFFALMLTPLFKKSKHVGIVEFFVTVAFGFI----------GLMII 346
Query: 163 KVATDPKEVLLLMS 176
+ + PK ++ L S
Sbjct: 347 LIESFPKSLVWLFS 360
>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
[Homo sapiens]
Length = 526
Score = 30.0 bits (66), Expect = 2.4
Identities = 20/52 (38%), Positives = 22/52 (42%), Gaps = 1/52 (1%)
Query: 226 SGQRYLSDPMEKHSSSYNQGGYNQDSYGSSSGYSQQASLGPTSDEFGQQPTG 277
S Q Y +S S + GY Q SY SS G SQ G S G TG
Sbjct: 29 SSQPYGQQSYSGYSQSTDTSGYGQSSY-SSYGQSQNTGYGTQSTPQGYGSTG 79
Score = 28.9 bits (63), Expect = 5.4
Identities = 19/55 (34%), Positives = 21/55 (38%), Gaps = 2/55 (3%)
Query: 222 GWHSSGQRYLSDPMEKHSSSYNQGGYNQDSYGS--SSGYSQQASLGPTSDEFGQQ 274
G SS Y P +S SYG S YSQQ S G +GQQ
Sbjct: 92 GQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQ 146
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.134 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,468,881
Number of Sequences: 37866
Number of extensions: 422594
Number of successful extensions: 1252
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 1086
Number of HSP's gapped (non-prelim): 154
length of query: 285
length of database: 18,247,518
effective HSP length: 101
effective length of query: 184
effective length of database: 14,423,052
effective search space: 2653841568
effective search space used: 2653841568
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.