Search of human proteins with 192807292

Search of human proteins with 192807292

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|192807292 keratin 24 [Homo sapiens]
         (525 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|192807292 keratin 24 [Homo sapiens]                               1028   0.0  
gi|195972866 keratin 10 [Homo sapiens]                                521   e-148
gi|4557699 keratin 12 [Homo sapiens]                                  486   e-137
gi|153945736 keratin 27 [Homo sapiens]                                469   e-132
gi|114431246 keratin 25D [Homo sapiens]                               460   e-129
gi|31559829 keratin 25 [Homo sapiens]                                 452   e-127
gi|131412225 keratin 13 isoform a [Homo sapiens]                      450   e-126
gi|131412228 keratin 13 isoform b [Homo sapiens]                      448   e-126
gi|15431310 keratin 14 [Homo sapiens]                                 444   e-125
gi|24430190 keratin 15 [Homo sapiens]                                 439   e-123
gi|55956899 keratin 9 [Homo sapiens]                                  434   e-121
gi|24430192 keratin 16 [Homo sapiens]                                 432   e-121
gi|4557701 keratin 17 [Homo sapiens]                                  428   e-120
gi|31559815 keratin 26 [Homo sapiens]                                 418   e-117
gi|24234699 keratin 19 [Homo sapiens]                                 401   e-112
gi|27894337 keratin 20 [Homo sapiens]                                 348   5e-96
gi|4504927 keratin 36 [Homo sapiens]                                  331   1e-90
gi|94538345 keratin 35 [Homo sapiens]                                 327   2e-89
gi|40354195 keratin 18 [Homo sapiens]                                 312   5e-85
gi|4557888 keratin 18 [Homo sapiens]                                  312   5e-85
gi|116488398 keratin 32 [Homo sapiens]                                301   1e-81
gi|14917117 keratin 33A [Homo sapiens]                                297   1e-80
gi|14917115 keratin 31 [Homo sapiens]                                 297   1e-80
gi|10337581 type I hair keratin 3B [Homo sapiens]                     291   8e-79
gi|14917119 keratin 34 [Homo sapiens]                                 288   8e-78
gi|27894339 keratin 23 [Homo sapiens]                                 288   1e-77
gi|125490370 type I hair keratin KA36 [Homo sapiens]                  276   4e-74
gi|148277620 type I hair keratin KA35 [Homo sapiens]                  274   1e-73
gi|15431318 keratin 38 [Homo sapiens]                                 259   4e-69
gi|55770882 keratin 37 [Homo sapiens]                                 254   1e-67

>gi|192807292 keratin 24 [Homo sapiens]
          Length = 525

 Score = 1028 bits (2659), Expect = 0.0
 Identities = 525/525 (100%), Positives = 525/525 (100%)

Query: 1   MSCSSRASSSRAGGSSSARVSAGGSSFSSGSRCGLGGSSAQGFRGGASSCSLSGGSSGAF 60
           MSCSSRASSSRAGGSSSARVSAGGSSFSSGSRCGLGGSSAQGFRGGASSCSLSGGSSGAF
Sbjct: 1   MSCSSRASSSRAGGSSSARVSAGGSSFSSGSRCGLGGSSAQGFRGGASSCSLSGGSSGAF 60

Query: 61  GGSFGGGFGSCSVGGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFY 120
           GGSFGGGFGSCSVGGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFY
Sbjct: 61  GGSFGGGFGSCSVGGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFY 120

Query: 121 SYGGGMGGGVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYG 180
           SYGGGMGGGVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYG
Sbjct: 121 SYGGGMGGGVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYG 180

Query: 181 PGSGDGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCL 240
           PGSGDGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCL
Sbjct: 181 PGSGDGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCL 240

Query: 241 RQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTV 300
           RQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTV
Sbjct: 241 RQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTV 300

Query: 301 EMNAAPGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNE 360
           EMNAAPGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNE
Sbjct: 301 EMNAAPGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNE 360

Query: 361 ITELKRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGE 420
           ITELKRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGE
Sbjct: 361 ITELKRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGE 420

Query: 421 TKCQNAEYKQLLDIKTRLEVEIETYRRLLDGEGGGSSFAEFGGRNSGSVNMGSRDLVSGD 480
           TKCQNAEYKQLLDIKTRLEVEIETYRRLLDGEGGGSSFAEFGGRNSGSVNMGSRDLVSGD
Sbjct: 421 TKCQNAEYKQLLDIKTRLEVEIETYRRLLDGEGGGSSFAEFGGRNSGSVNMGSRDLVSGD 480

Query: 481 SRSGSCSGQGRDSSKTRVTKTIVEELVDGKVVSSQVSSISEVKVK 525
           SRSGSCSGQGRDSSKTRVTKTIVEELVDGKVVSSQVSSISEVKVK
Sbjct: 481 SRSGSCSGQGRDSSKTRVTKTIVEELVDGKVVSSQVSSISEVKVK 525


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score =  521 bits (1341), Expect = e-148
 Identities = 297/503 (59%), Positives = 349/503 (69%), Gaps = 24/503 (4%)

Query: 2   SCSSRASSSRAGGSSSARVSAGGSSFSS----GSRCGLGGS-SAQGFRGGASSCSLSGGS 56
           S S   SSSR+GG        GG   SS     S+  LGG  S+ GF GG+ S   SGG 
Sbjct: 6   SSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGG- 64

Query: 57  SGAFGGSFGGGFGSCSVGGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGAT 116
            G FGGS  GG+G     GGFGG  GS  G  G SSFGG  G   G G  G   F  G+ 
Sbjct: 65  -GCFGGS-SGGYGGL---GGFGG--GSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSF 117

Query: 117 GGFYSYGGGMGGGVG-----DGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENK 171
           GG    GGG GGG G     DGGL SG EK TMQNLNDRLA+YLDKVRALEE+N +LE K
Sbjct: 118 GGGGFGGGGFGGGFGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGK 177

Query: 172 IKEWYDKYGPGSGDGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFR 231
           IKEWY+K+G  +   G  RDYSKYY  I+DL+NQI+  T +NA I+L IDNARLAADDFR
Sbjct: 178 IKEWYEKHG--NSHQGEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFR 235

Query: 232 LKYENELCLRQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQ 291
           LKYENE+ LRQSVEADINGLR+VLD+LT+T++DLEMQIES TEELAYL+KNHEEEMK+++
Sbjct: 236 LKYENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLR 295

Query: 292 GSSGGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDA 351
             S G+V VEMNAAPG DLT+LLN+MR+QYE+LAEQNR++AE  FN++S  L  +I  + 
Sbjct: 296 NVSTGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNI 355

Query: 352 GAATSAKNEITELKRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALE 411
              +S K+EITEL+R +QALEIELQSQLA+K SLE +LA+TE  Y  QLS+IQ QISALE
Sbjct: 356 EQISSYKSEITELRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALE 415

Query: 412 EEICQIWGETKCQNAEYKQLLDIKTRLEVEIETYRRLLDGEGGGSSFAEFGGRNSGSVNM 471
           E++ QI  ET+CQN EY+QLLDIK RLE EI+TYR LL+GEG        GGR  GS   
Sbjct: 416 EQLQQIRAETECQNTEYQQLLDIKIRLENEIQTYRSLLEGEGSSGG----GGRGGGSFGG 471

Query: 472 GSRDLVSGDSRSGSCSGQGRDSS 494
           G     SG   SG   G G   S
Sbjct: 472 GYGGGSSGGGSSGGGHGGGHGGS 494



 Score = 84.0 bits (206), Expect = 3e-16
 Identities = 52/113 (46%), Positives = 60/113 (53%), Gaps = 11/113 (9%)

Query: 28  SSGSRCGLGGSSAQGFRGGASSCSLSGGS-SGAFGGSFGGGFGSCSVGGGFGGASGSGTG 86
           SSG     GGS   G+ GG+S    SGG   G  GGS GGG+G  S GGG      SG G
Sbjct: 458 SSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGG-----SSGGG 512

Query: 87  FGGGSSFGG-----VSGFGRGSGFCGSSRFSSGATGGFYSYGGGMGGGVGDGG 134
           +GGGSS GG       G+G GS   G   +  G++GG  S GGG GGG   GG
Sbjct: 513 YGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGG 565



 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 57/126 (45%), Positives = 64/126 (50%), Gaps = 9/126 (7%)

Query: 5   SRASSSRAGGSSSARV---SAGGSSFSSGSRCGLGGSSAQGFRGGASSCSLSGGSSGAFG 61
           S     R GGS        S+GG S   G   G GGSS  G+ GG+S    SGG  G  G
Sbjct: 458 SSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYG--G 515

Query: 62  GSFGGGFGSCSVGGGFGGASGSGTG-FGGGSSFGGVS---GFGRGSGFCGSSRFSSGATG 117
           GS  GG G  S GG  GG+SG G G +GGGSS GG S   G+G GS   G    SSG+ G
Sbjct: 516 GSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVG 575

Query: 118 GFYSYG 123
              S G
Sbjct: 576 ESSSKG 581



 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 55/110 (50%), Positives = 59/110 (53%), Gaps = 18/110 (16%)

Query: 37  GSSAQGFRGGASSCSLSGGSSGAFGGSFGGG-FGSCSVGGGFGGASG--SGTGFGGGSSF 93
           GSS  G RGG           G+FGG +GGG  G  S GGG GG  G  SG G+GGGSS 
Sbjct: 457 GSSGGGGRGG-----------GSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSG 505

Query: 94  GGVS--GFGRGSGFCGSSRFSSGATGGFYS--YGGGMGGGVGDGGLFSGG 139
           GG S  G+G GS   G    SSG  GG  S   GGG GGG   GG  SGG
Sbjct: 506 GGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGG 555



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 38/71 (53%), Positives = 39/71 (54%), Gaps = 4/71 (5%)

Query: 69  GSCSVGGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYSYGGGMGG 128
           G  S GGG  G    G G+GGGSS GG SG G G G  GS   S G  GG  S GG  GG
Sbjct: 455 GEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGS---SGGGYGGGSSGGGSSGG 511

Query: 129 GVGDGGLFSGG 139
           G G GG  SGG
Sbjct: 512 GYG-GGSSSGG 521



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 24/66 (36%), Positives = 29/66 (43%), Gaps = 1/66 (1%)

Query: 2   SCSSRASSSRAGGSSSARVSAGGSSFSSGSRCGLGGSSAQGFRGGASSCSLSGGSSGAFG 61
           S S     S +GG        GG  +  GS  G G SS  G+ GG+SS      SSG+ G
Sbjct: 517 SSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGG-GSSSGGGYGGGSSSGGHKSSSSGSVG 575

Query: 62  GSFGGG 67
            S   G
Sbjct: 576 ESSSKG 581


>gi|4557699 keratin 12 [Homo sapiens]
          Length = 494

 Score =  486 bits (1250), Expect = e-137
 Identities = 280/523 (53%), Positives = 361/523 (69%), Gaps = 55/523 (10%)

Query: 4   SSRASSSRAGGSSSARVSAG--GSSFSSGSRCGLGGSSAQGFRGGASSCSLSGGSSGAFG 61
           SS++   R  G S++ V +G  GS+F  G+ CG          GG S+ S+ G SSG   
Sbjct: 22  SSQSVIGRPRGMSASSVGSGYGGSAFGFGASCG----------GGFSAASMFGSSSG--- 68

Query: 62  GSFGGGFGSCSVGGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYS 121
             FGGG GS S+ GG G  +G G   GGGS FGG+     G GF GS             
Sbjct: 69  --FGGGSGS-SMAGGLG--AGYGRALGGGS-FGGL-----GMGFGGSPG----------- 106

Query: 122 YGGGMGGGVG-DGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYG 180
            GG +G   G DGGL SG EK+TMQNLNDRLA+YLDKVRALEEANT+LENKI+EWY+  G
Sbjct: 107 -GGSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRG 165

Query: 181 PGSGDGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCL 240
            G+ D  S  DYSKYY +IEDLRN+II+A++ NA ++L IDNARLAA+DFR+KYENEL L
Sbjct: 166 TGTADA-SQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELAL 224

Query: 241 RQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTV 300
           RQ VEADINGLR+VLD+LT+TR+DLEMQIES  EELAY++KNHE+E+++ +    GEV+V
Sbjct: 225 RQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSV 284

Query: 301 EMNAAPGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNE 360
           EM+AAPG DLT+LLNDMRAQYE +AEQNR++AE  F ++S  L+ +IST+     S+K+E
Sbjct: 285 EMDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSE 344

Query: 361 ITELKRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGE 420
           +T+L+R  Q LEIELQSQLAMK SLE +LA+ E  Y AQLS++Q  IS LE ++ Q+  +
Sbjct: 345 VTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRAD 404

Query: 421 TKCQNAEYKQLLDIKTRLEVEIETYRRLLDGEGGGSSFAEFGGRNSGSVNMGSRDLVSGD 480
            + QN ++++LL++K RLE+EIETYRRLLDGE  G    E               L   D
Sbjct: 405 AERQNVDHQRLLNVKARLELEIETYRRLLDGEAQGDGLEE--------------SLFVTD 450

Query: 481 SRS-GSCSGQGRDSSKTRVTKTIVEELVDGKVVSSQVSSISEV 522
           S+S    +   +D +KTR  KT+V+E+V+G+VVSSQV  I E+
Sbjct: 451 SKSQAQSTDSSKDPTKTRKIKTVVQEMVNGEVVSSQVQEIEEL 493


>gi|153945736 keratin 27 [Homo sapiens]
          Length = 459

 Score =  469 bits (1208), Expect = e-132
 Identities = 268/467 (57%), Positives = 329/467 (70%), Gaps = 41/467 (8%)

Query: 69  GSCSVGGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYSYGGGMGG 128
           GSC  G G    S  G GFG G++ G     G GSGF  +   SS A G    YGGG+GG
Sbjct: 13  GSCG-GTGSVRLSSGGAGFGAGNTCGVP---GIGSGFSCAFGGSSSAGG----YGGGLGG 64

Query: 129 GVG--------DGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYG 180
           G          + GL SG EK TMQNLNDRLA+YL+ VRALEEAN DLE KIK WY+K+G
Sbjct: 65  GSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWYEKFG 124

Query: 181 PGSGDGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCL 240
           PGS  G    DYS+Y+ II++L+NQII+AT  NA ++L  DNARL ADDFRLK+ENEL L
Sbjct: 125 PGSCRG-LDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENELAL 183

Query: 241 RQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTV 300
            QSVEADINGLR+VLD+LT+ R+DLE+Q+E+ +EELAYL+KNHEEEMK +Q ++GG V V
Sbjct: 184 HQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGNVNV 243

Query: 301 EMNAAPGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNE 360
           EMNAAPG DLT LLN+MRA+YE LAEQNRR+AE  FN++SASLQ QIS DAGA TSA+NE
Sbjct: 244 EMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSARNE 303

Query: 361 ITELKRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGE 420
           + E+KRTLQ LEIELQS LA K SLE +L +TE+ Y AQL++IQ QI ALEE++ Q+  E
Sbjct: 304 LIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTE 363

Query: 421 TKCQNAEYKQLLDIKTRLEVEIETYRRLLDGEGGGSSFAE-FGGRNSGSVNMGSRDLVSG 479
           T+ Q  EY+QLLDIK  LE EIETY  L+DGE G  S ++ +GG  +             
Sbjct: 364 TEGQKLEYEQLLDIKVHLEKEIETYCLLIDGEDGSCSKSKGYGGPGN------------- 410

Query: 480 DSRSGSCSGQGRDSSKTRVTKTIVEEL-VDGKVVSSQVSSISEVKVK 525
                    Q +DSSKT + KT+VEE+   GKV+SS+V ++ E   K
Sbjct: 411 ---------QTKDSSKTTIVKTVVEEIDPRGKVLSSRVHTVEEKSTK 448


>gi|114431246 keratin 25D [Homo sapiens]
          Length = 464

 Score =  460 bits (1184), Expect = e-129
 Identities = 267/499 (53%), Positives = 330/499 (66%), Gaps = 59/499 (11%)

Query: 27  FSSGSR---CGLGGSSAQGFRGGASSCSLSGGSSGAFGGSFGGGFGSCSVGGGFGGASGS 83
           FS+GSR      G  S +   GGA         S A GGS  G   SC++GGG G   G 
Sbjct: 5   FSNGSRHVCLRSGAGSVRPLNGGAGFAG-----SSACGGSVAGSEFSCALGGGLGSVPG- 58

Query: 84  GTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYSYGGGMGGGVGDGGLFSGGEKQT 143
                 GS  GG  G     GF GS                       +GGL SG EK T
Sbjct: 59  ------GSHAGGALGNAACIGFAGS-----------------------EGGLLSGNEKVT 89

Query: 144 MQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRDYSKYYSIIEDLR 203
           MQNLNDRLA+YLD VRALEEAN +LE KIK WY+KYGPGS  G    DYS+Y+  IEDL+
Sbjct: 90  MQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRG-LDHDYSRYHLTIEDLK 148

Query: 204 NQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGLRKVLDDLTMTRS 263
           N+II++T  NA +IL IDNARLAADDFRLKYENEL L Q+VEADINGLR+VLD+LT+ R+
Sbjct: 149 NKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRVLDELTLCRT 208

Query: 264 DLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAPGTDLTKLLNDMRAQYEE 323
           D E+Q ES +EE+ YL+KNHEEEMK +Q ++GG V VEMNAAPG DL  LLN+MRA+YE 
Sbjct: 209 DQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLLNNMRAEYEA 268

Query: 324 LAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQALEIELQSQLAMKS 383
           LAEQNR++AE  FN++SASLQ QIS D+GAAT A++++TE++RTLQ LEI+LQS +A K 
Sbjct: 269 LAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQLQSLMATKH 328

Query: 384 SLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQLLDIKTRLEVEIE 443
           SLE +L +TE+ Y  QL++IQ QI ALEE++ Q+  ET+ Q  EY+ LLD+K  LE EIE
Sbjct: 329 SLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDVKVHLEKEIE 388

Query: 444 TYRRLLDGEGGGSSFAEFGGRNSGSVNMGSRDLVSGDSRSGSCSGQGRDSSKTRVTKTIV 503
           TY RL+DG+G   S ++  G  SGS    S+DL                 SKT + KT+V
Sbjct: 389 TYCRLIDGDGNSCSKSK--GFGSGSPGNSSKDL-----------------SKTTLVKTVV 429

Query: 504 EELVD-GKVVSSQVSSISE 521
           EEL   GKV+SS++ SI E
Sbjct: 430 EELDQRGKVLSSRIHSIEE 448



 Score = 30.8 bits (68), Expect = 3.2
 Identities = 20/54 (37%), Positives = 24/54 (44%), Gaps = 4/54 (7%)

Query: 14 GSSSARVSAGGSSFSSGSRCGL----GGSSAQGFRGGASSCSLSGGSSGAFGGS 63
          GSS+   S  GS FS     GL    GGS A G  G A+    +G   G   G+
Sbjct: 32 GSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAGSEGGLLSGN 85


>gi|31559829 keratin 25 [Homo sapiens]
          Length = 450

 Score =  452 bits (1163), Expect = e-127
 Identities = 253/450 (56%), Positives = 322/450 (71%), Gaps = 31/450 (6%)

Query: 81  SGSGTGFGGGSSFG-----GVSGFGRGSGFCGSSRFSSGATGGFYSYGGG---MGGGVGD 132
           +GS   +GGG+SFG     G+SG   GSGF  SS F   ++GG  + GGG    G  V +
Sbjct: 18  TGSLRLYGGGTSFGTGNSCGISGI--GSGF--SSAFGGSSSGG--NTGGGNPCAGFTVNE 71

Query: 133 GGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRDY 192
            GL SG EK TMQNLNDRLA+YLD V ALEEAN DLE KIK WY+K+GPGS   G   DY
Sbjct: 72  RGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGS-CRGLDHDY 130

Query: 193 SKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGLR 252
           S+Y+ II+DL+NQIIA+T  NA  +L IDNARL ADDFRLKYENEL L QSVEAD+NGLR
Sbjct: 131 SRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLR 190

Query: 253 KVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAPGTDLTK 312
           +VLD++T+ R+DLE+Q E+ +EE+ YL+KNH+EEM+ +Q ++GG V VEMNAAPG DLT 
Sbjct: 191 RVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTV 250

Query: 313 LLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQALE 372
           LLN+MRA+YE LAEQNRR+AE  FN++SASLQ QIS D GA TSA+NE+TE+KRTLQ LE
Sbjct: 251 LLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLE 310

Query: 373 IELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQLL 432
           IELQS LA K SLE +L +TE+ Y AQL++IQ QI ALEE++ Q+  ET+ Q  EY+QLL
Sbjct: 311 IELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLL 370

Query: 433 DIKTRLEVEIETYRRLLDGEGGGSSFAEFGGRNSGSVNMGSRDLVSGDSRSGSCSGQGRD 492
           DIK  LE EIETY  L+ G+ G      +  ++ GS N+GS               Q +D
Sbjct: 371 DIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGS---------------QVKD 415

Query: 493 SSKTRVTKTIVEELVD-GKVVSSQVSSISE 521
            +K  V K ++EE+    K++++++ S+ E
Sbjct: 416 PAKAIVVKKVLEEVDQRSKILTTRLHSLEE 445


>gi|131412225 keratin 13 isoform a [Homo sapiens]
          Length = 458

 Score =  450 bits (1157), Expect = e-126
 Identities = 253/476 (53%), Positives = 319/476 (67%), Gaps = 36/476 (7%)

Query: 17  SARVSAGGSSFSSGSRCGLGGSSAQGFRGGASSCS---LSGGSSGAFGGSFGGGFGSCSV 73
           S R+ +  +S+  G     GGS   G   G S+CS   +SGGS+G +GG       SC  
Sbjct: 2   SLRLQSSSASYGGGFG---GGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGV-----SC-- 51

Query: 74  GGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYSYGGGMGGGVGDG 133
             GFGG +GSG G G G   GG  G G G GF G      G  GGF  +      G  DG
Sbjct: 52  --GFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGG------GFAGGFVDF------GACDG 97

Query: 134 GLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRDYS 193
           GL +G EK TMQNLNDRLA+YL+KVRALEEAN DLE KI++W+ K  P S +    RDYS
Sbjct: 98  GLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPE----RDYS 153

Query: 194 KYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGLRK 253
            YY  IE+LR++I+ AT+EN  +IL IDNARLAADDFRLKYENEL LRQSVEADINGLR+
Sbjct: 154 PYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRR 213

Query: 254 VLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAPGTDLTKL 313
           VLD+LT++++DLEMQIES  EELAY++KNHEEEMK       G+V VEM+A PG DLT++
Sbjct: 214 VLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRV 273

Query: 314 LNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQALEI 373
           L +MR QYE +AE+NRR+AEE F+ +SA L  ++ST+     ++K EITEL+RTLQ LEI
Sbjct: 274 LAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEI 333

Query: 374 ELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQLLD 433
           ELQSQL+MK+ LE T+A+TE  Y  QL +IQ  IS++E ++ ++  E +CQN EYK LLD
Sbjct: 334 ELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLD 393

Query: 434 IKTRLEVEIETYRRLLDGE-----GGGSSFAEFGGRNSGSVNMGSRDLVSGDSRSG 484
           IKTRLE EI TYR LL+G+     G  SS      R++      S  + +  + SG
Sbjct: 394 IKTRLEQEIATYRSLLEGQDAKMIGFPSSAGSVSPRSTSVTTTSSASVTTTSNASG 449



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 27/78 (34%), Positives = 32/78 (41%), Gaps = 15/78 (19%)

Query: 2  SCSSRASSSRAGGSSSARVSAG-----GSSFSSGSRCGLGGSSAQGFRGGASSCSLSGGS 56
          +CS+R  S  + G     VS G     GS F  G   GLGG    G  GG       GG 
Sbjct: 31 TCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLGGG-----FGGGF 85

Query: 57 SGAFGGSFGGGFGSCSVG 74
          +G F       FG+C  G
Sbjct: 86 AGGF-----VDFGACDGG 98


>gi|131412228 keratin 13 isoform b [Homo sapiens]
          Length = 420

 Score =  448 bits (1152), Expect = e-126
 Identities = 246/439 (56%), Positives = 307/439 (69%), Gaps = 31/439 (7%)

Query: 17  SARVSAGGSSFSSGSRCGLGGSSAQGFRGGASSCS---LSGGSSGAFGGSFGGGFGSCSV 73
           S R+ +  +S+  G     GGS   G   G S+CS   +SGGS+G +GG       SC  
Sbjct: 2   SLRLQSSSASYGGGFG---GGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGV-----SC-- 51

Query: 74  GGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYSYGGGMGGGVGDG 133
             GFGG +GSG G G G   GG  G G G GF G      G  GGF  +      G  DG
Sbjct: 52  --GFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGG------GFAGGFVDF------GACDG 97

Query: 134 GLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRDYS 193
           GL +G EK TMQNLNDRLA+YL+KVRALEEAN DLE KI++W+ K  P S +    RDYS
Sbjct: 98  GLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPE----RDYS 153

Query: 194 KYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGLRK 253
            YY  IE+LR++I+ AT+EN  +IL IDNARLAADDFRLKYENEL LRQSVEADINGLR+
Sbjct: 154 PYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRR 213

Query: 254 VLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAPGTDLTKL 313
           VLD+LT++++DLEMQIES  EELAY++KNHEEEMK       G+V VEM+A PG DLT++
Sbjct: 214 VLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRV 273

Query: 314 LNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQALEI 373
           L +MR QYE +AE+NRR+AEE F+ +SA L  ++ST+     ++K EITEL+RTLQ LEI
Sbjct: 274 LAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEI 333

Query: 374 ELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQLLD 433
           ELQSQL+MK+ LE T+A+TE  Y  QL +IQ  IS++E ++ ++  E +CQN EYK LLD
Sbjct: 334 ELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLD 393

Query: 434 IKTRLEVEIETYRRLLDGE 452
           IKTRLE EI TYR LL+G+
Sbjct: 394 IKTRLEQEIATYRSLLEGQ 412



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 27/78 (34%), Positives = 32/78 (41%), Gaps = 15/78 (19%)

Query: 2  SCSSRASSSRAGGSSSARVSAG-----GSSFSSGSRCGLGGSSAQGFRGGASSCSLSGGS 56
          +CS+R  S  + G     VS G     GS F  G   GLGG    G  GG       GG 
Sbjct: 31 TCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLGGG-----FGGGF 85

Query: 57 SGAFGGSFGGGFGSCSVG 74
          +G F       FG+C  G
Sbjct: 86 AGGF-----VDFGACDGG 98


>gi|15431310 keratin 14 [Homo sapiens]
          Length = 472

 Score =  444 bits (1143), Expect = e-125
 Identities = 263/497 (52%), Positives = 335/497 (67%), Gaps = 50/497 (10%)

Query: 25  SSFSSGSRCGLGGSSAQGFRGGASSCS--LSGGSSGAFGGSFGGGFGSCSVGGGFGGASG 82
           SS S    CG+GG    G  GG+S  S  L+GGS  A   ++GGG    S     GGA G
Sbjct: 10  SSSSMKGSCGIGG----GIGGGSSRISSVLAGGSCRA-PSTYGGGLSVSSSRFSSGGAYG 64

Query: 83  SGTGFGGG-----SSFGGVSGFGRGSGFCGSSRFSSGATGGFYSYGGGMGGGVGDGGLFS 137
            G G+GGG     SSFG  SGFG G G        +G  GGF   GGG  GG    GL  
Sbjct: 65  LGGGYGGGFSSSSSSFG--SGFGGGYG----GGLGAGLGGGF---GGGFAGG---DGLLV 112

Query: 138 GGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRDYSKYYS 197
           G EK TMQNLNDRLA+YLDKVRALEEAN DLE KI++WY +  P        +DYS Y+ 
Sbjct: 113 GSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEI-----KDYSPYFK 167

Query: 198 IIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGLRKVLDD 257
            IEDLRN+I+ ATV+NA ++L IDNARLAADDFR KYE EL LR SVEADINGLR+VLD+
Sbjct: 168 TIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDE 227

Query: 258 LTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAPGTDLTKLLNDM 317
           LT+ R+DLEMQIES  EELAYL+KNHEEEM  ++G  GG+V VEM+AAPG DL+++LN+M
Sbjct: 228 LTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEM 287

Query: 318 RAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQALEIELQS 377
           R QYE++AE+NR++AEE F  ++  L  +++T++    S K+EI+EL+RT+Q LEIELQS
Sbjct: 288 RDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQS 347

Query: 378 QLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQLLDIKTR 437
           QL+MK+SLE +L +T+  Y  QL++IQ  I ++EE++ Q+  E + QN EYK LLD+KTR
Sbjct: 348 QLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTR 407

Query: 438 LEVEIETYRRLLDGEGGGSSFAEFGGRNSGSVNMGSRDLVSGDSRSGSCSGQGRDSSKTR 497
           LE EI TYRRLL+GE    S ++F   +SGS    SRD+                +S +R
Sbjct: 408 LEQEIATYRRLLEGEDAHLSSSQF---SSGS--QSSRDV----------------TSSSR 446

Query: 498 VTKTIVEELVDGKVVSS 514
             +T V ++ DGKVVS+
Sbjct: 447 QIRTKVMDVHDGKVVST 463


>gi|24430190 keratin 15 [Homo sapiens]
          Length = 456

 Score =  439 bits (1128), Expect = e-123
 Identities = 257/497 (51%), Positives = 320/497 (64%), Gaps = 45/497 (9%)

Query: 25  SSFSSGSRCGLGGSSAQGFRGGASSCSLSGGSSGAFGGSFGGGFGSCSVGGGFGG--ASG 82
           ++F   S    GG S    RGG    SL  G  G  GGS  GG GS S+        +SG
Sbjct: 3   TTFLQTSSSTFGGGST---RGG----SLLAGGGGFGGGSLSGGGGSRSISASSARFVSSG 55

Query: 83  SGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYSYGGGMGGGVGDGGLFSGGEKQ 142
           SG G+GGG     V GFG G+G      F  G  GGF   GGG GGG  DGGL SG EK 
Sbjct: 56  SGGGYGGGMR---VCGFGGGAGSVFGGGFGGGVGGGF---GGGFGGG--DGGLLSGNEKI 107

Query: 143 TMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRDYSKYYSIIEDL 202
           TMQNLNDRLA+YLDKVRALEEAN DLE KI +WY K  P S +     DYS+Y+  IE+L
Sbjct: 108 TMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSPEC----DYSQYFKTIEEL 163

Query: 203 RNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGLRKVLDDLTMTR 262
           R++I+A T++N+ +IL IDNARLAADDFRLKYENEL LRQ VEADINGLR+VLD+LT+ R
Sbjct: 164 RDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLAR 223

Query: 263 SDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAPGTDLTKLLNDMRAQYE 322
           +DLEMQIE   EELAYL+KNHEEEMK       G+V VEM+AAPG DLT++L +MR QYE
Sbjct: 224 TDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYE 283

Query: 323 ELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQALEIELQSQLAMK 382
            +AE+NRR+ E  F  ++  L  +++++     ++K EIT+L+RT+Q LEIELQSQL+MK
Sbjct: 284 AMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLSMK 343

Query: 383 SSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQLLDIKTRLEVEI 442
           + LE +LA+TE  Y  QL +IQ  I  LE ++ ++  E + QN EYK LLDIKTRLE EI
Sbjct: 344 AGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQEI 403

Query: 443 ETYRRLLDGEGGGSSFAEFGGRNSGSVNMGSRDLVSGDSRSGSCSGQGRDSSKTRVTKTI 502
            TYR LL+G+            ++    +G R+         + SG G  SS   +    
Sbjct: 404 ATYRSLLEGQ------------DAKMAGIGIRE---------ASSGGGGSSSNFHIN--- 439

Query: 503 VEELVDGKVVSSQVSSI 519
           VEE VDG+VVSS    I
Sbjct: 440 VEESVDGQVVSSHKREI 456


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score =  434 bits (1116), Expect = e-121
 Identities = 254/515 (49%), Positives = 326/515 (63%), Gaps = 35/515 (6%)

Query: 1   MSCSSRASS--SRAGGSSSARVSAGGS---SFSSGSRCGLGG-----SSAQGFRGGASS- 49
           MSC   +SS  SR+GG     + +GGS   S+S  S  G GG     SS+ G+ GG+S  
Sbjct: 1   MSCRQFSSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRV 60

Query: 50  CSLSGGSSG--AFGGSFGGGFGSCSVGGGFGGAS-----GSGTGFGGGSSFGGVSGFGRG 102
           C   GG S   ++GG  GGGF + S+GGGFGG S      SG G+     FGG  G G G
Sbjct: 61  CGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSG 120

Query: 103 SGFCGSSRFSSGATGGFYSYGGGMGGGVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALE 162
            GF G   + SG  GGF  +GGG GGG  DGG+ +  EK TMQ LN RLA+YLDKV+ALE
Sbjct: 121 GGFGGG--YGSGF-GGFGGFGGGAGGG--DGGILTANEKSTMQELNSRLASYLDKVQALE 175

Query: 163 EANTDLENKIKEWYDKYGPGSGDGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDN 222
           EAN DLENKI++WYDK GP +      ++YS YY+ I+DL++QI+  TV N   +L IDN
Sbjct: 176 EANNDLENKIQDWYDKKGPAAIQ----KNYSPYYNTIDDLKDQIVDLTVGNNKTLLDIDN 231

Query: 223 ARLAADDFRLKYENELCLRQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKN 282
            R+  DDFR+K+E E  LRQ V+ADINGLR+VLD+LTM +SDLEMQ E+  EEL  L+KN
Sbjct: 232 TRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQYETLQEELMALKKN 291

Query: 283 HEEEMKNMQGSSGGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSAS 342
           H+EEM  + G + G+V VE+N APG DLTK LNDMR +YE+L  +NR++ E ++  Q   
Sbjct: 292 HKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKNRKDIENQYETQITQ 351

Query: 343 LQAQISTDAGAATSAKNEITELKRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSE 402
           ++ ++S+      S+  E+T+L+  +Q LEIELQSQL+ K++LE +L DT+  Y  QL  
Sbjct: 352 IEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLEDTKNRYCGQLQM 411

Query: 403 IQTQISALEEEICQIWGETKCQNAEYKQLLDIKTRLEVEIETYRRLLDG-----EGGGSS 457
           IQ QIS LE +I  +  E +CQN EY  LL IK RLE EIETY  LL+G     E  G+ 
Sbjct: 412 IQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLEGGQEDFESSGAG 471

Query: 458 FAEFGGR--NSGSVNMGSRDLVSGDSRSGSCSGQG 490
               GGR  + GS   GSR   SG S  G  SG G
Sbjct: 472 KIGLGGRGGSGGSYGRGSRG-GSGGSYGGGGSGGG 505



 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 55/119 (46%), Positives = 64/119 (53%), Gaps = 10/119 (8%)

Query: 21  SAGGSSFSSGSRCGLGGSSAQGFRGGASSCSLSGGSSGAFGGSFGGGFGSCSVGGGFGGA 80
           S+G      G R G GGS  +G RGG+      GGS G +GG  G   GS   GG +GG 
Sbjct: 467 SSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGS---GGSYGGG 523

Query: 81  SGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYSYGGGMGGGVGDGGLFSGG 139
           SGSG G GGG  +GG SG G   G  G     SG +GG  +YGGG G G G GG + GG
Sbjct: 524 SGSGGGSGGG--YGGGSGGGHSGGSGGG---HSGGSGG--NYGGGSGSGGGSGGGYGGG 575



 Score = 89.7 bits (221), Expect = 6e-18
 Identities = 61/136 (44%), Positives = 71/136 (52%), Gaps = 17/136 (12%)

Query: 6   RASSSRAGGSSSARVSAGGSSFSSGSRCGLGGSSAQGFRGGASSCSLSGGSSGAFGGSFG 65
           R S   +GGS     S GG    SGSR G GGS    + GG+ S    GGS G +GG  G
Sbjct: 487 RGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGS----YGGGSGS---GGGSGGGYGGGSG 539

Query: 66  GGFGSCSVGGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYSYGGG 125
           GG    S G G G + GSG  +GGGS  GG SG G G G       S G +GG  S+GGG
Sbjct: 540 GGH---SGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGG-----SGSRGGSGG--SHGGG 589

Query: 126 MGGGVGDGGLFSGGEK 141
            G G   GG + GGE+
Sbjct: 590 SGFGGESGGSYGGGEE 605



 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 58/132 (43%), Positives = 65/132 (49%), Gaps = 12/132 (9%)

Query: 2   SCSSRASSSRAGGSSSARVSAGGSSFSSGSRCGLGGSSAQGFRGGAS---SCSLSGGSSG 58
           S  S       GG      S GGS  S G   G GG S  G+ GG+    S    GG SG
Sbjct: 493 SGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSG 552

Query: 59  AFGGSFGGGFGSCSVGGGFGGASGSGTGFGGGS--SFGGVSGF-GRGSGFCGSSRFSSGA 115
             GG++GGG GS   GGG GG  G G+G  GGS  S GG SGF G   G  G    +SG+
Sbjct: 553 GSGGNYGGGSGS---GGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGS 609

Query: 116 TGGFYSYGGGMG 127
            GG   YGGG G
Sbjct: 610 GGG---YGGGSG 618



 Score = 69.7 bits (169), Expect = 6e-12
 Identities = 49/118 (41%), Positives = 54/118 (45%), Gaps = 18/118 (15%)

Query: 8   SSSRAGGSSSARVSAGGSSFSSGSRCGLGGSSAQGFRGGASSCSLSG---------GSSG 58
           S SR G   S     GGS    GS  G GG S  G  GG+      G         GS G
Sbjct: 510 SGSRGGSGGSY---GGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGG 566

Query: 59  AFGGSFGGGFGSCSVGGGFGGASGSGTGFG---GGSSFGGVSGFGRGSGFCGSSRFSS 113
             GG +GGG GS    GG GG+ G G+GFG   GGS  GG    G G G+ G S  SS
Sbjct: 567 GSGGGYGGGSGS---RGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKSS 621



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 32/86 (37%), Positives = 42/86 (48%), Gaps = 9/86 (10%)

Query: 7   ASSSRAGGSSSARVSAGGSSFSSGSRCGLGGSSAQGFRGGASSCSLSGGSSGA------- 59
           +    +GGS        G ++  GS  G GG S  G+ GG+ S   SGGS G        
Sbjct: 538 SGGGHSGGSGGGHSGGSGGNYGGGS--GSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGE 595

Query: 60  FGGSFGGGFGSCSVGGGFGGASGSGT 85
            GGS+GGG  +   GGG+GG SG  +
Sbjct: 596 SGGSYGGGEEASGSGGGYGGGSGKSS 621


>gi|24430192 keratin 16 [Homo sapiens]
          Length = 473

 Score =  432 bits (1110), Expect = e-121
 Identities = 251/485 (51%), Positives = 321/485 (66%), Gaps = 36/485 (7%)

Query: 2   SCSSR-ASSSRAGGSSSARVSAGGSSFSSGSRCGLGGSSAQGFRGGASSCSLSGGSSGAF 60
           +CS +  SSS   GS       GG S    S    G   A    GG  S S    S GA 
Sbjct: 3   TCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGGAC 62

Query: 61  GGSFGGGFGSCSVGGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFY 120
           G   GGG+     GGGF  +S  G+GFGGG  +GG    G G+GF G      G   GF 
Sbjct: 63  G--LGGGY-----GGGFSSSSSFGSGFGGG--YGG----GLGAGFGG------GLGAGF- 102

Query: 121 SYGGGMGGGVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYG 180
             GGG  GG    GL  G EK TMQNLNDRLA+YLDKVRALEEAN DLE KI++WY +  
Sbjct: 103 --GGGFAGG---DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQR 157

Query: 181 PGSGDGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCL 240
           P        +DYS Y+  IEDLRN+IIAAT+ENA  IL IDNARLAADDFR KYE+EL L
Sbjct: 158 P-----SEIKDYSPYFKTIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELAL 212

Query: 241 RQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTV 300
           RQ+VEAD+NGLR+VLD+LT+ R+DLEMQIE   EELAYLRKNHEEEM  ++G +GG+V V
Sbjct: 213 RQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNV 272

Query: 301 EMNAAPGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNE 360
           EM+AAPG DL+++LN+MR QYE++AE+NRR+AE  F  ++  L  ++++++    S+++E
Sbjct: 273 EMDAAPGVDLSRILNEMRDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSE 332

Query: 361 ITELKRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGE 420
           +TEL+R LQ LEIELQSQL+MK+SLE +L +T+  Y  QLS+IQ  I ++EE++ Q+  E
Sbjct: 333 VTELRRVLQGLEIELQSQLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCE 392

Query: 421 TKCQNAEYKQLLDIKTRLEVEIETYRRLLDGEGGGSSFAEFGGRNSGSVNMGSRDLVSGD 480
            + Q+ EY+ LLD+KTRLE EI TYRRLL+GE      A    + +   +  SR++ +  
Sbjct: 393 MEQQSQEYQILLDVKTRLEQEIATYRRLLEGED-----AHLSSQQASGQSYSSREVFTSS 447

Query: 481 SRSGS 485
           S S S
Sbjct: 448 SSSSS 452


>gi|4557701 keratin 17 [Homo sapiens]
          Length = 432

 Score =  428 bits (1101), Expect = e-120
 Identities = 244/469 (52%), Positives = 317/469 (67%), Gaps = 54/469 (11%)

Query: 48  SSCSLSGGSSGAFGGSFGGGFGSCSVGGGFG-GASGSGTGFGGGSSFGGVSGFGRGSGFC 106
           +S S   GSSG  GGS      SC + GG G G+   G+  G GS+ GG S         
Sbjct: 9   TSSSSIKGSSGLGGGS---SRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSY-------- 57

Query: 107 GSSRFSSGATGGFYSYGGGMGGGVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANT 166
            SS +S G+ GG+ S  GG+ G      L +GGEK TMQNLNDRLA+YLDKVRALEEANT
Sbjct: 58  -SSCYSFGSGGGYGSSFGGVDG------LLAGGEKATMQNLNDRLASYLDKVRALEEANT 110

Query: 167 DLENKIKEWYDKYGPGSGDGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLA 226
           +LE KI++WY +  PG       RDYS+YY  IE+L+N+I+ ATV+NA I+L IDNARLA
Sbjct: 111 ELEVKIRDWYQRQAPGPA-----RDYSQYYRTIEELQNKILTATVDNANILLQIDNARLA 165

Query: 227 ADDFRLKYENELCLRQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEE 286
           ADDFR K+E E  LR SVEADINGLR+VLD+LT+ R+DLEMQIE+  EELAYL+KNHEEE
Sbjct: 166 ADDFRTKFETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEE 225

Query: 287 MKNMQGSSGGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQ 346
           M  ++G  GGE+ VEM+AAPG DL+++LN+MR QYE++AE+NR++AE+ F  ++  L  +
Sbjct: 226 MNALRGQVGGEINVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNRE 285

Query: 347 ISTDAGAATSAKNEITELKRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQ 406
           ++T++    S K+EI+EL+RT+QALEIELQSQL+MK+SLEG LA+TE  Y  QLS+IQ  
Sbjct: 286 VATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGL 345

Query: 407 ISALEEEICQIWGETKCQNAEYKQLLDIKTRLEVEIETYRRLLDGEGGGSSFAEFGGRNS 466
           I ++EE++ Q+  E + QN EYK LLD+KTRLE EI TYRRLL+GE              
Sbjct: 346 IGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGE-------------- 391

Query: 467 GSVNMGSRDLVSGDSRSGSCSGQGRDSSKTRVTKTIVEELVDGKVVSSQ 515
                               +   ++   TR  +TIVEE+ DGKV+SS+
Sbjct: 392 ----------------DAHLTQYKKEPVTTRQVRTIVEEVQDGKVISSR 424


>gi|31559815 keratin 26 [Homo sapiens]
          Length = 468

 Score =  418 bits (1075), Expect = e-117
 Identities = 248/468 (52%), Positives = 309/468 (66%), Gaps = 28/468 (5%)

Query: 65  GGGFGSCSVGGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYSYGG 124
           GG    CS  G  G  SG GTGF  G+   G SG  R S  C     SSG  G F + GG
Sbjct: 7   GGSRRICSRTGS-GRLSGGGTGFVAGNVCVG-SG-ARSSFSCTLEGISSG--GSFCNSGG 61

Query: 125 GMGGGVGDG------GLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDK 178
           G+G G   G       L SG EK TMQNLNDRLA+YLD V ALEEAN DLE KIK  Y+K
Sbjct: 62  GLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYEK 121

Query: 179 YGPGSGDGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENEL 238
             PGS       DYS+Y+S+IEDL+ QI +AT+ NA I+L  DNARL ADDFRLKYENEL
Sbjct: 122 CEPGSSREHD-HDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENEL 180

Query: 239 CLRQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEV 298
            L  SVEAD +GLR+VLD+LT+  +DLE+Q E+ +EEL YL+K+HEEEM+ +Q ++GG V
Sbjct: 181 ALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNV 240

Query: 299 TVEMNAAPGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAK 358
            VEMNA PG DLT LLN+MRA+YE+LAEQNR++AE  FN++SA+LQ QIS   GAAT+A+
Sbjct: 241 NVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAAR 300

Query: 359 NEITELKRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIW 418
           NE+TELKR LQ LEIELQS +A+K S E +LA+TE  Y  QL +IQ QI  +EE++ QI 
Sbjct: 301 NELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIR 360

Query: 419 GETKCQNAEYKQLLDIKTRLEVEIETYRRLLDGEGGGSSFAEFGGRNSGSVNMGSRDLVS 478
            ET+ Q  EY+QLLD+K  LE EI+ Y  LLDGE   S    +  +    VN G+     
Sbjct: 361 TETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKSTCYKSKGYRPVNSGN----- 415

Query: 479 GDSRSGSCSGQGRDSSKTRVTKTIVEELVD-GKVVSSQVSSISEVKVK 525
                     Q +DS++  + KT+VEEL   G ++S +V S+ E   K
Sbjct: 416 ----------QAKDSTEETIVKTVVEELDQIGNLLSLRVHSVEEKSSK 453


>gi|24234699 keratin 19 [Homo sapiens]
          Length = 400

 Score =  401 bits (1030), Expect = e-112
 Identities = 213/386 (55%), Positives = 282/386 (73%), Gaps = 13/386 (3%)

Query: 72  SVGGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCG----SSRFSSGATGGFYSYGGGMG 127
           S    FGG  G    FG G +F   S  G GSG  G    S+RF S ++ G  +YGGG G
Sbjct: 10  SATSSFGGLGGGSVRFGPGVAFRAPSIHG-GSGGRGVSVSSARFVSSSSSG--AYGGGYG 66

Query: 128 GGV-GDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDG 186
           G +    GL +G EK TMQNLNDRLA+YLDKVRALE AN +LE KI++WY K GPG    
Sbjct: 67  GVLTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPS-- 124

Query: 187 GSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEA 246
              RDYS YY+ I+DLR++I+ AT+EN+ I+L IDNARLAADDFR K+E E  LR SVEA
Sbjct: 125 ---RDYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEA 181

Query: 247 DINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAP 306
           DINGLR+VLD+LT+ R+DLEMQIE   EELAYL+KNHEEE+  ++G  GG+V+VE+++AP
Sbjct: 182 DINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAP 241

Query: 307 GTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKR 366
           GTDL K+L+DMR+QYE +AEQNR++AE  F  ++  L  +++        +++E+T+L+R
Sbjct: 242 GTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRR 301

Query: 367 TLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNA 426
           TLQ LEIELQSQL+MK++LE TLA+TEA + AQL+ IQ  IS +E ++  +  +++ QN 
Sbjct: 302 TLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQ 361

Query: 427 EYKQLLDIKTRLEVEIETYRRLLDGE 452
           EY++L+DIK+RLE EI TYR LL+G+
Sbjct: 362 EYQRLMDIKSRLEQEIATYRSLLEGQ 387



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 21/63 (33%), Positives = 29/63 (46%), Gaps = 5/63 (7%)

Query: 9  SSRAGGSSSARVSAGGSSFSSGSRCGLGGSSAQGFRGG-----ASSCSLSGGSSGAFGGS 63
          S R   ++S+    GG S   G        S  G  GG     +S+  +S  SSGA+GG 
Sbjct: 5  SYRQSSATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYGGG 64

Query: 64 FGG 66
          +GG
Sbjct: 65 YGG 67


>gi|27894337 keratin 20 [Homo sapiens]
          Length = 424

 Score =  348 bits (894), Expect = 5e-96
 Identities = 192/401 (47%), Positives = 270/401 (67%), Gaps = 32/401 (7%)

Query: 121 SYGGGMGGGVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYG 180
           +YG  + GG   G LF G EK  MQNLNDRLA+YL+KVR LE++N+ LE +IK+WY+   
Sbjct: 54  NYGSDLTGG---GDLFVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNA 110

Query: 181 PGSGDGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCL 240
           P +G     RDYS YY  IE+LR+QI  A ++NA  +L IDNA+LAA+DFRLKYE E  +
Sbjct: 111 PRAG-----RDYSAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGI 165

Query: 241 RQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTV 300
           R +VEAD+ GL KV DDLT+ ++DLE+QIE   ++LA L+K H+EE+  +    G  V V
Sbjct: 166 RLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNV 225

Query: 301 EMNAAPGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNE 360
           E++AAPG +L  ++N+MR +YE +A++N +EA+E+F +Q+A LQ Q++ +       + +
Sbjct: 226 EVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQ 285

Query: 361 ITELKRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGE 420
           +TEL+RT Q+LEIELQS L+MK SLE TL +T+A Y +QL+ +Q+ +S+LE ++ QI   
Sbjct: 286 LTELRRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSN 345

Query: 421 TKCQNAEYKQLLDIKTRLEVEIETYRRLLDGEGGGSSFAEFGGRNSGSVNMGSRDLVSGD 480
            + QN EY  LLDIKTRLE EI TYRRLL+GE                      D+ + +
Sbjct: 346 MERQNNEYHILLDIKTRLEQEIATYRRLLEGE----------------------DVKTTE 383

Query: 481 SRSGSCSGQGRDSSKTRVTKTIVEELVDGKVVSSQVSSISE 521
            +  +   + RD  KTR  KT+V+E+VDGKVVSS+V  + E
Sbjct: 384 YQLSTL--EERDIKKTRKIKTVVQEVVDGKVVSSEVKEVEE 422


>gi|4504927 keratin 36 [Homo sapiens]
          Length = 467

 Score =  331 bits (848), Expect = 1e-90
 Identities = 204/459 (44%), Positives = 272/459 (59%), Gaps = 16/459 (3%)

Query: 63  SFGGGFGSCSVGGGFGGASG-SGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYS 121
           S G   G C   GG    S     G     S  G +G+   S   G S   S   G + S
Sbjct: 11  STGSIKGLCGTAGGISRVSSIRSVGSCRVPSLAGAAGY-ISSARSGLSGLGSCLPGSYLS 69

Query: 122 YGGGMGGGVGDGGLF-----SGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWY 176
                 G VG GG F     +G EK+TMQ LNDRLANYL+KVR LE  N +LE++I+EWY
Sbjct: 70  SECHTSGFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQLERENAELESRIQEWY 129

Query: 177 DKYGPGSGDGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYEN 236
           +   P         DY  Y+  IED + +I+    ENA ++L IDNA+LAADDFR KYE 
Sbjct: 130 EFQIPYICP-----DYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYET 184

Query: 237 ELCLRQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGG 296
           EL LRQ VEADINGLR++LD+LT+ ++DLE Q+ES  EEL  L+KNHEEE+  ++   G 
Sbjct: 185 ELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGD 244

Query: 297 EVTVEMNAAPGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATS 356
            + VE++AAP  DL K+L DMR QYE L E NRR+ E  FN Q+  L  Q+ + +     
Sbjct: 245 RLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQC 304

Query: 357 AKNEITELKRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQ 416
            + EI EL+RT+ ALEIELQ+Q +M++SLE TLA+TEA Y +QL+++Q  IS +E ++ +
Sbjct: 305 CQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSE 364

Query: 417 IWGETKCQNAEYKQLLDIKTRLEVEIETYRRLLDGEGGGSSFAEFGGRNSGSVNMGSRDL 476
           I  + + QN EY+ LLD+K RLE EI TYR LL+GE                + + S   
Sbjct: 365 IRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKLPPQPCATACKPVIRVPSVPP 424

Query: 477 VSGDSRSGSCSGQGRDSSKTRVTKTIVEELVDGKVVSSQ 515
           V     S  C+   +  ++ R   TI EE+ DGKV+SS+
Sbjct: 425 VP-CVPSVPCTPAPQVGTQIR---TITEEIRDGKVISSR 459


>gi|94538345 keratin 35 [Homo sapiens]
          Length = 455

 Score =  327 bits (838), Expect = 2e-89
 Identities = 187/410 (45%), Positives = 260/410 (63%), Gaps = 11/410 (2%)

Query: 47  ASSCSLSGGSSGAFGGSFGGGFGSCSVGGGFGGASGSGTGFGG-GSSFGGVS-GFGRGSG 104
           AS C  +G SSG+     G   GS  V   +  +S           SF   S G GR S 
Sbjct: 2   ASKCLKAGFSSGSLKSPGGASGGSTRVSAMYSSSSCKLPSLSPVARSFSACSVGLGRSSY 61

Query: 105 FCGSS--RFSSGATGGFYSYGGGMGGGVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALE 162
              S        A G   SY GG GG  G+G + +G EK+TMQ+LNDRLA YL+KVR LE
Sbjct: 62  RATSCLPALCLPAGGFATSYSGG-GGWFGEG-ILTGNEKETMQSLNDRLAGYLEKVRQLE 119

Query: 163 EANTDLENKIKEWYDKYGPGSGDGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDN 222
           + N  LE++I+EW ++  P         DY  Y+  IE+L+ + + +  ENA +++ IDN
Sbjct: 120 QENASLESRIREWCEQQVPYMCP-----DYQSYFRTIEELQKKTLCSKAENARLVVEIDN 174

Query: 223 ARLAADDFRLKYENELCLRQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKN 282
           A+LAADDFR KYE E+ LRQ VE+DINGLR++LDDLT+ +SDLE Q+ES  EEL  L+KN
Sbjct: 175 AKLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKN 234

Query: 283 HEEEMKNMQGSSGGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSAS 342
           HEEE+ +++   G  + VE++AAP  DL ++L +MR QYE L E NRR+AE+  + QS  
Sbjct: 235 HEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEE 294

Query: 343 LQAQISTDAGAATSAKNEITELKRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSE 402
           L  Q+ + +    S + EI EL+RT+ ALEIELQ+Q +M+ +LE TLA+TEA Y +QL++
Sbjct: 295 LNQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQ 354

Query: 403 IQTQISALEEEICQIWGETKCQNAEYKQLLDIKTRLEVEIETYRRLLDGE 452
           +Q  I+ +E ++ +I  + + QN EY+ LLD++ RLE EI TYR LL+ E
Sbjct: 355 MQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESE 404


>gi|40354195 keratin 18 [Homo sapiens]
          Length = 430

 Score =  312 bits (799), Expect = 5e-85
 Identities = 191/444 (43%), Positives = 264/444 (59%), Gaps = 40/444 (9%)

Query: 72  SVGGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYSYGGGMGGGVG 131
           S+G     + G+       S + G  G G       S+ F  G   G  + G   GG  G
Sbjct: 15  SLGSVQAPSYGARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGSGGLATGIA-GGLAG 73

Query: 132 DGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRD 191
            GG+ +  EK+TMQ+LNDRLA+YLD+VR+LE  N  LE+KI+E  +K GP        RD
Sbjct: 74  MGGIQN--EKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGP------QVRD 125

Query: 192 YSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGL 251
           +S Y+ IIEDLR QI A TV+NA I+L IDNARLAADDFR+KYE EL +RQSVE DI+GL
Sbjct: 126 WSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGL 185

Query: 252 RKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGS-SGGEVTVEMNAAPGTDL 310
           RKV+DD  +TR  LE +IE+  EEL +++KNHEEE+K +Q   +   +TVE++A    DL
Sbjct: 186 RKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDL 245

Query: 311 TKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQA 370
            K++ D+RAQY+ELA +NR E ++ +++Q       ++T +    +A+  +TEL+RT+Q+
Sbjct: 246 AKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQS 305

Query: 371 LEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQ 430
           LEI+L S   +K+SLE +L + EA Y  Q+ ++   +  LE E+ Q   E + Q  EY+ 
Sbjct: 306 LEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEA 365

Query: 431 LLDIKTRLEVEIETYRRLL-DGEGGGSSFAEFGGRNSGSVNMGSRDLVSGDSRSGSCSGQ 489
           LL+IK +LE EI TYRRLL DGE                      D   GD+   S    
Sbjct: 366 LLNIKVKLEAEIATYRRLLEDGE----------------------DFNLGDALDSS---- 399

Query: 490 GRDSSKTRVTKTIVEELVDGKVVS 513
              +S   + KT    +VDGKVVS
Sbjct: 400 ---NSMQTIQKTTTRRIVDGKVVS 420



 Score = 30.0 bits (66), Expect = 5.4
 Identities = 21/51 (41%), Positives = 27/51 (52%), Gaps = 4/51 (7%)

Query: 15 SSSARVSAGGSSFSSGSRCGLGGSSAQGFRGGASSCSLSGGSSGAFGGSFG 65
          SS+A V AG     SGSR  +  S++  FRGG  S  L+ G +G   G  G
Sbjct: 30 SSAASVYAGAGG--SGSRISVSRSTS--FRGGMGSGGLATGIAGGLAGMGG 76


>gi|4557888 keratin 18 [Homo sapiens]
          Length = 430

 Score =  312 bits (799), Expect = 5e-85
 Identities = 191/444 (43%), Positives = 264/444 (59%), Gaps = 40/444 (9%)

Query: 72  SVGGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYSYGGGMGGGVG 131
           S+G     + G+       S + G  G G       S+ F  G   G  + G   GG  G
Sbjct: 15  SLGSVQAPSYGARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGSGGLATGIA-GGLAG 73

Query: 132 DGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRD 191
            GG+ +  EK+TMQ+LNDRLA+YLD+VR+LE  N  LE+KI+E  +K GP        RD
Sbjct: 74  MGGIQN--EKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGP------QVRD 125

Query: 192 YSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGL 251
           +S Y+ IIEDLR QI A TV+NA I+L IDNARLAADDFR+KYE EL +RQSVE DI+GL
Sbjct: 126 WSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGL 185

Query: 252 RKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGS-SGGEVTVEMNAAPGTDL 310
           RKV+DD  +TR  LE +IE+  EEL +++KNHEEE+K +Q   +   +TVE++A    DL
Sbjct: 186 RKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDL 245

Query: 311 TKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQA 370
            K++ D+RAQY+ELA +NR E ++ +++Q       ++T +    +A+  +TEL+RT+Q+
Sbjct: 246 AKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQS 305

Query: 371 LEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQ 430
           LEI+L S   +K+SLE +L + EA Y  Q+ ++   +  LE E+ Q   E + Q  EY+ 
Sbjct: 306 LEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEA 365

Query: 431 LLDIKTRLEVEIETYRRLL-DGEGGGSSFAEFGGRNSGSVNMGSRDLVSGDSRSGSCSGQ 489
           LL+IK +LE EI TYRRLL DGE                      D   GD+   S    
Sbjct: 366 LLNIKVKLEAEIATYRRLLEDGE----------------------DFNLGDALDSS---- 399

Query: 490 GRDSSKTRVTKTIVEELVDGKVVS 513
              +S   + KT    +VDGKVVS
Sbjct: 400 ---NSMQTIQKTTTRRIVDGKVVS 420



 Score = 30.0 bits (66), Expect = 5.4
 Identities = 21/51 (41%), Positives = 27/51 (52%), Gaps = 4/51 (7%)

Query: 15 SSSARVSAGGSSFSSGSRCGLGGSSAQGFRGGASSCSLSGGSSGAFGGSFG 65
          SS+A V AG     SGSR  +  S++  FRGG  S  L+ G +G   G  G
Sbjct: 30 SSAASVYAGAGG--SGSRISVSRSTS--FRGGMGSGGLATGIAGGLAGMGG 76


>gi|116488398 keratin 32 [Homo sapiens]
          Length = 448

 Score =  301 bits (771), Expect = 1e-81
 Identities = 156/333 (46%), Positives = 230/333 (69%), Gaps = 10/333 (3%)

Query: 125 GMGGGVGDG-----GLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKY 179
           G+ G +G G     G F+G EK+TMQ LNDRLA+YL +VR LE+ N +LE++I+E     
Sbjct: 76  GISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRIQE----- 130

Query: 180 GPGSGDGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELC 239
              S       DY  ++  IE+L+ +I+    ENA ++++IDNA+LAADDFR KYE EL 
Sbjct: 131 ASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAELA 190

Query: 240 LRQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVT 299
           +RQ VEADINGLR++LDDLT+ ++DLE Q+ES  EEL  L+KNHEEE+ +++   G  + 
Sbjct: 191 MRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDRLN 250

Query: 300 VEMNAAPGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKN 359
           +E++AAP  DLT++L +MR QYE + E NRR+ EE FN Q   L  Q++T +    + ++
Sbjct: 251 IEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNYQS 310

Query: 360 EITELKRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWG 419
           +I +L+RT+  LEIELQ+Q +++ SLE TL ++EA Y +QL+++Q  I+ +E ++ +I  
Sbjct: 311 DIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEIRA 370

Query: 420 ETKCQNAEYKQLLDIKTRLEVEIETYRRLLDGE 452
           + + QN EY+ LLD++ RLE EI TYR LL+ E
Sbjct: 371 DLERQNQEYQVLLDVRARLEGEINTYRSLLENE 403


>gi|14917117 keratin 33A [Homo sapiens]
          Length = 404

 Score =  297 bits (761), Expect = 1e-80
 Identities = 156/319 (48%), Positives = 220/319 (68%), Gaps = 5/319 (1%)

Query: 134 GLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRDYS 193
           G F+G EK+TMQ LNDRLA+YL+KVR LE  N +LEN I+E   +  P          Y 
Sbjct: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVC-----ASYQ 104

Query: 194 KYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGLRK 253
            Y+  IE+L+ +I+ +  ENA +++ IDNA+LA+DDFR KYE EL LRQ VE+DINGLR+
Sbjct: 105 SYFKTIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRR 164

Query: 254 VLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAPGTDLTKL 313
           +LD+LT+ RSDLE Q+ES  EEL  L++NHE+E+  ++   G  + VE++AAP  DL ++
Sbjct: 165 ILDELTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQV 224

Query: 314 LNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQALEI 373
           LN+ R+QYE L E NRRE E+ F  Q+  L  Q+ + +    S + EI EL+RT+ ALEI
Sbjct: 225 LNETRSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEI 284

Query: 374 ELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQLLD 433
           ELQ+Q  ++ SLE TL ++EA Y +QLS++Q  I+ +E ++ +I  + + QN EY+ LLD
Sbjct: 285 ELQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLD 344

Query: 434 IKTRLEVEIETYRRLLDGE 452
           ++ RLE EI TYR LL+ E
Sbjct: 345 VRARLECEINTYRSLLESE 363


>gi|14917115 keratin 31 [Homo sapiens]
          Length = 416

 Score =  297 bits (761), Expect = 1e-80
 Identities = 155/319 (48%), Positives = 219/319 (68%), Gaps = 5/319 (1%)

Query: 134 GLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRDYS 193
           G F+G EK+TMQ LNDRLA+YL+KVR LE  N +LEN I+E   +  P          Y 
Sbjct: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPS-----YQ 104

Query: 194 KYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGLRK 253
            Y+  IE+L+ +I+    ENA +++ IDNA+LAADDFR KY+ EL LRQ VE+DINGLR+
Sbjct: 105 SYFKTIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRR 164

Query: 254 VLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAPGTDLTKL 313
           +LD+LT+ +SDLE Q+ES  EEL  L+ NHE+E+  ++   G  + VE++AAP  DL ++
Sbjct: 165 ILDELTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRV 224

Query: 314 LNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQALEI 373
           LN+ R+QYE L E NRRE E+ F  Q+  L  Q+ + +    S + EI EL+RT+ ALEI
Sbjct: 225 LNETRSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEI 284

Query: 374 ELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQLLD 433
           ELQ+Q  ++ SLE TL ++EA Y +QLS++Q+ I+ +E ++ +I  + + QN EY+ LLD
Sbjct: 285 ELQAQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLD 344

Query: 434 IKTRLEVEIETYRRLLDGE 452
           ++ RLE EI TYR LL+ E
Sbjct: 345 VRARLECEINTYRSLLESE 363


>gi|10337581 type I hair keratin 3B [Homo sapiens]
          Length = 404

 Score =  291 bits (746), Expect = 8e-79
 Identities = 154/319 (48%), Positives = 218/319 (68%), Gaps = 5/319 (1%)

Query: 134 GLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRDYS 193
           G F+G EK+TMQ LNDRLA+YL+KVR LE  N +LEN I+E   +  P          Y 
Sbjct: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPS-----YQ 104

Query: 194 KYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGLRK 253
            Y+  IE+L+ +I+ +  ENA +++ IDNA+LAADDFR KY+ E  LRQ VE+DIN LR+
Sbjct: 105 SYFKTIEELQQKILCSKSENARLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLRR 164

Query: 254 VLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAPGTDLTKL 313
           +LD+LT+ RSDLE Q+ES  EEL  L++NHE+E+  ++   G  + VE++AAP  DL ++
Sbjct: 165 ILDELTLCRSDLEAQMESLKEELLSLKQNHEQEVNTLRCQLGDRLNVEVDAAPAVDLNQV 224

Query: 314 LNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQALEI 373
           LN+ R QYE L E NRRE E+ F  Q+  L  Q+ + +    S + EI EL+RT+ ALEI
Sbjct: 225 LNETRNQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEI 284

Query: 374 ELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQLLD 433
           ELQ+Q  ++ SLE TL ++EA Y +QLS++Q+ I+ +E ++ +I  + + QN EY+ LLD
Sbjct: 285 ELQAQHNLRYSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLD 344

Query: 434 IKTRLEVEIETYRRLLDGE 452
           ++ RLE EI TYR LL+ E
Sbjct: 345 VRARLECEINTYRSLLESE 363


>gi|14917119 keratin 34 [Homo sapiens]
          Length = 436

 Score =  288 bits (737), Expect = 8e-78
 Identities = 151/319 (47%), Positives = 217/319 (68%), Gaps = 5/319 (1%)

Query: 134 GLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRDYS 193
           G F+G EK+TMQ LNDRLA+YL+KVR LE  N +LE  I+E   +  P          Y 
Sbjct: 92  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELEKLIQERSQQQEPLLCPS-----YQ 146

Query: 194 KYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGLRK 253
            Y+  IE+L+ +I+ A  ENA ++++IDNA+LA+DDFR KY+ E  LR  VE+DIN +R+
Sbjct: 147 SYFKTIEELQQKILCAKAENARLVVNIDNAKLASDDFRSKYQTEQSLRLLVESDINSIRR 206

Query: 254 VLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAPGTDLTKL 313
           +LD+LT+ +SDLE Q+ES  EEL  L+KNHEEE+  ++   G  + VE++ AP  DL ++
Sbjct: 207 ILDELTLCKSDLESQVESLREELICLKKNHEEEVNTLRSQLGDRLNVEVDTAPTVDLNQV 266

Query: 314 LNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQALEI 373
           LN+ R+QYE L E NRRE E+ F  Q+  L  Q+ + +    S + EI EL+RT+ ALEI
Sbjct: 267 LNETRSQYEALVEINRREVEQWFATQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEI 326

Query: 374 ELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQLLD 433
           ELQ+Q  ++ SLE TL ++EA Y +QLS++Q+ I+ +E ++ +I  + + QN EY+ LLD
Sbjct: 327 ELQAQHNLRDSLENTLTESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQNQEYQVLLD 386

Query: 434 IKTRLEVEIETYRRLLDGE 452
           ++ RLE EI TYR LL+ E
Sbjct: 387 VRARLECEINTYRSLLESE 405


>gi|27894339 keratin 23 [Homo sapiens]
          Length = 422

 Score =  288 bits (736), Expect = 1e-77
 Identities = 175/442 (39%), Positives = 252/442 (57%), Gaps = 36/442 (8%)

Query: 83  SGTGFGGGSSFGGVSGFGRGS---GFCGSSRFSSGATGGFYSYGGGMGGGVGDGGLFSGG 139
           S +  G G  +G    F R     G  G +R S   T       GG  G      L  G 
Sbjct: 12  SASFHGAGGGWGRPRSFPRAPTVHGGAGGARISLSFTTRSCPPPGGSWGSGRSSPLLGGN 71

Query: 140 EKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRDYSKYYSII 199
            K TMQNLNDRLA+YL+KVRALEEAN  LE++I +W+ +  PGS      +DYS+Y   I
Sbjct: 72  GKATMQNLNDRLASYLEKVRALEEANMKLESRILKWHQQRDPGSK-----KDYSQYEENI 126

Query: 200 EDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGLRKVLDDLT 259
             L+ QI+   + NA IIL IDNAR+A DDF LKYENE   ++ +E ++ GLR+ LD+LT
Sbjct: 127 THLQEQIVDGKMTNAQIILLIDNARMAVDDFNLKYENEHSFKKDLEIEVEGLRRTLDNLT 186

Query: 260 MTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAPGTDLTKLLNDMRA 319
           +  +DLE ++E   +EL  ++K+HE+EM+     S   V V+++  P  DL K+L DMR 
Sbjct: 187 IVTTDLEQEVEGMRKELILMKKHHEQEMEKHHVPSDFNVNVKVDTGPREDLIKVLEDMRQ 246

Query: 320 QYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQALEIELQSQL 379
           +YE + ++  R+ +  + +QSA++  + ++ A    S + +I ELKRT QALEI+LQ+Q 
Sbjct: 247 EYELIIKKKHRDLDTWYKEQSAAMSQEAASPA-TVQSRQGDIHELKRTFQALEIDLQTQY 305

Query: 380 AMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQLLDIKTRLE 439
           + KS+LE  L++T++ Y  +L ++Q  IS  EEE+ Q+  E + QN EY+ LL IKT LE
Sbjct: 306 STKSALENMLSETQSRYSCKLQDMQEIISHYEEELTQLRHELERQNNEYQVLLGIKTHLE 365

Query: 440 VEIETYRRLLDGEGGGSSFAEFGGRNSGSVNMGSRDLVSGDSRSGSCSGQGRDSSKTRVT 499
            EI TYRRLL+GE  G+       R     +M                      S T   
Sbjct: 366 KEITTYRRLLEGESEGT-------REESKSSM--------------------KVSATPKI 398

Query: 500 KTIVEELVDGKVVSSQVSSISE 521
           K I +E ++G++V  QV+ I +
Sbjct: 399 KAITQETINGRLVLCQVNEIQK 420


>gi|125490370 type I hair keratin KA36 [Homo sapiens]
          Length = 431

 Score =  276 bits (705), Expect = 4e-74
 Identities = 149/321 (46%), Positives = 215/321 (66%), Gaps = 5/321 (1%)

Query: 132 DGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRD 191
           + G+F+  EK+TMQ LNDRLA+YL+KVR+LEE N +LE++I+E  ++  P         D
Sbjct: 81  EDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCP-----D 135

Query: 192 YSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGL 251
           Y +Y++ IEDL+ +I+    EN+ + + +DN +LA DDF+ KYE+EL LRQ +EADI+ L
Sbjct: 136 YQRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSL 195

Query: 252 RKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAPGTDLT 311
             +L++LT+ +SDLE  +ES  E+L  L+KNHEEE+  ++   G  ++VE++ AP  DL 
Sbjct: 196 HGILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLN 255

Query: 312 KLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQAL 371
           ++L++MR Q E +   NRREAEE    Q+  L  Q  + A      + EI ELKRT  AL
Sbjct: 256 RVLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASAL 315

Query: 372 EIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQL 431
           EIELQ+Q ++  SLE T+A+TEA Y +QL++IQ  I  LE ++ +I  + + QN EY+ L
Sbjct: 316 EIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVL 375

Query: 432 LDIKTRLEVEIETYRRLLDGE 452
           LD+K RLE EI TY  LLD E
Sbjct: 376 LDVKARLEGEINTYWGLLDSE 396


>gi|148277620 type I hair keratin KA35 [Homo sapiens]
          Length = 491

 Score =  274 bits (701), Expect = 1e-73
 Identities = 162/395 (41%), Positives = 234/395 (59%), Gaps = 18/395 (4%)

Query: 131 GDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGR 190
           G+G   +  EK+TMQ LN+RLANYL KVR LE  N +LE+KI+E  +K  P         
Sbjct: 89  GEG--INSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCP----- 141

Query: 191 DYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADING 250
           DY  YY+ IE+L+ +I+    EN+ ++  IDN +L ADD R KYE E+ LRQ VE+D NG
Sbjct: 142 DYLSYYTTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANG 201

Query: 251 LRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAPGTDL 310
           L+++L+ LT+ ++DLE Q++S  EEL  L+ NH+EE+ ++Q   G  + +E+ AAP  DL
Sbjct: 202 LKQILNVLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADL 261

Query: 311 TKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQA 370
            ++L +MR QYE + E NR++ E+ FN Q   L  Q+ T +      + EI EL+R++  
Sbjct: 262 NQVLQEMRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNT 321

Query: 371 LEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQ 430
           LE+ELQ+Q  M+ S E  L +TEA Y A L++IQ+ I  LE ++ +I    + QN EY+ 
Sbjct: 322 LEVELQAQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEI 381

Query: 431 LLDIKTRLEVEIETYRRLLDGEGGGSSF---------AEFGGRNSGSVNMGSRDLVSGD- 480
           LLD+K+RLE EI TYR LL+   G             + +    SG++   +    S   
Sbjct: 382 LLDVKSRLECEITTYRSLLESSDGKRPCYPRATKCEPSPWTSCKSGAIESTAPACTSSSP 441

Query: 481 -SRSGSCSGQGRDSSKTRVTKTIVEELVDGKVVSS 514
            S    CS  G  S       TI +E+ DGKV+SS
Sbjct: 442 CSLKEHCSACGPLSRILVKICTITKEIKDGKVISS 476


>gi|15431318 keratin 38 [Homo sapiens]
          Length = 456

 Score =  259 bits (662), Expect = 4e-69
 Identities = 142/328 (43%), Positives = 213/328 (64%), Gaps = 6/328 (1%)

Query: 125 GMGGGVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSG 184
           G+ G  G+  L +G EK+TMQ LNDRLANYL+KVR LE+ N +LE  + E    +     
Sbjct: 90  GICGAYGENTL-NGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLERSKCH----- 143

Query: 185 DGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSV 244
           +     DY  Y+  IE+L+ +I+ +  ENA +I+ IDNA+LAADDFR+K E+E  LRQ V
Sbjct: 144 ESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQLV 203

Query: 245 EADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNA 304
           EAD  G +K+LDD T+ ++DLE Q ES  EE   L+ NHE+E+K ++   G ++ +E++ 
Sbjct: 204 EADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRIELDI 263

Query: 305 APGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITEL 364
            P  DL ++L +MRAQYE + E NR++ E+ F  QS  +  Q  + +      ++EI EL
Sbjct: 264 EPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILEL 323

Query: 365 KRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQ 424
           + T+ ALE+E Q+Q  +K  L+ +L + E  +  +L+++Q+ IS +EE++ +I  + + Q
Sbjct: 324 RCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQ 383

Query: 425 NAEYKQLLDIKTRLEVEIETYRRLLDGE 452
           N EY+ LLD+KTRLE EI TYR LL+ E
Sbjct: 384 NQEYQVLLDVKTRLENEIATYRNLLESE 411


>gi|55770882 keratin 37 [Homo sapiens]
          Length = 449

 Score =  254 bits (650), Expect = 1e-67
 Identities = 140/328 (42%), Positives = 208/328 (63%), Gaps = 6/328 (1%)

Query: 125 GMGGGVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSG 184
           G+ G  G   L +G EK+TM+ LNDRLANYL+KVR LE+ N +LE  + E    +     
Sbjct: 90  GICGAYGKNTL-NGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCH----- 143

Query: 185 DGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSV 244
           +     DY  Y+  IE+L+ +I+ +  ENA +I+ IDNA+LAADDFR+K E+E  L Q V
Sbjct: 144 ESTVCPDYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLV 203

Query: 245 EADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNA 304
           EAD  G +K+LDD T+ ++DLE Q ES  EE   L+ NHE+E+K ++   G +  +E++ 
Sbjct: 204 EADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDI 263

Query: 305 APGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITEL 364
            P  DL ++L +MRAQYE + E N ++ E+ F  QS  +  Q  + +      ++EI EL
Sbjct: 264 EPTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILEL 323

Query: 365 KRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQ 424
           + T+ ALE+E Q+Q  +K  L+ +L + E  Y  +L+++Q+ IS LEE++ +I  + + Q
Sbjct: 324 RCTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQ 383

Query: 425 NAEYKQLLDIKTRLEVEIETYRRLLDGE 452
           N EY+ LLD+K RLE EI TYR LL+ E
Sbjct: 384 NQEYQVLLDVKARLENEIATYRNLLESE 411


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.129    0.357 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,178,521
Number of Sequences: 37866
Number of extensions: 1001296
Number of successful extensions: 23758
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 445
Number of HSP's successfully gapped in prelim test: 541
Number of HSP's that attempted gapping in prelim test: 6742
Number of HSP's gapped (non-prelim): 6824
length of query: 525
length of database: 18,247,518
effective HSP length: 107
effective length of query: 418
effective length of database: 14,195,856
effective search space: 5933867808
effective search space used: 5933867808
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.