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Search of human proteins with 191250773
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|191250773 spire homolog 1 isoform a [Homo sapiens]
(756 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|191250773 spire homolog 1 isoform a [Homo sapiens] 1514 0.0
gi|191250771 spire homolog 1 isoform b [Homo sapiens] 1477 0.0
gi|191250775 spire homolog 1 isoform c [Homo sapiens] 1233 0.0
gi|55749600 spire homolog 2 [Homo sapiens] 507 e-143
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 45 3e-04
gi|61966703 NHS-like 2 [Homo sapiens] 45 3e-04
gi|116268127 kinase non-catalytic C-lobe domain (KIND) containin... 44 6e-04
gi|51871374 UTP14, U3 small nucleolar ribonucleoprotein, homolog... 43 0.001
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 40 0.008
gi|61966919 hypothetical protein LOC442444 [Homo sapiens] 39 0.014
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 39 0.018
gi|68508961 centromere protein C 1 [Homo sapiens] 38 0.040
gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 37 0.052
gi|24497609 nucleoporin 62kDa [Homo sapiens] 37 0.052
gi|24497607 nucleoporin 62kDa [Homo sapiens] 37 0.052
gi|24497605 nucleoporin 62kDa [Homo sapiens] 37 0.052
gi|24497603 nucleoporin 62kDa [Homo sapiens] 37 0.052
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 37 0.089
gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapi... 37 0.089
gi|239745904 PREDICTED: hypothetical protein, partial [Homo sapi... 37 0.089
gi|6005830 plakophilin 3 [Homo sapiens] 37 0.089
gi|187936935 GRAM domain containing 1C [Homo sapiens] 37 0.089
gi|227496489 multiple C2 domains, transmembrane 2 isoform 2 [Hom... 36 0.12
gi|227496440 multiple C2 domains, transmembrane 2 isoform 1 [Hom... 36 0.12
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 36 0.12
gi|110349788 absent, small, or homeotic 1-like [Homo sapiens] 36 0.12
gi|114431248 hypothetical protein LOC205717 [Homo sapiens] 36 0.15
gi|110349719 titin isoform N2-A [Homo sapiens] 36 0.15
gi|38373677 guanine nucleotide-releasing factor 2 isoform b [Hom... 36 0.15
gi|38373675 guanine nucleotide-releasing factor 2 isoform a [Hom... 36 0.15
>gi|191250773 spire homolog 1 isoform a [Homo sapiens]
Length = 756
Score = 1514 bits (3919), Expect = 0.0
Identities = 756/756 (100%), Positives = 756/756 (100%)
Query: 1 MAQAAGPAGGGEPRTEAVGGEGPREPGAAGGAAGGSRDALSLEEILRLYNQPINEEQAWA 60
MAQAAGPAGGGEPRTEAVGGEGPREPGAAGGAAGGSRDALSLEEILRLYNQPINEEQAWA
Sbjct: 1 MAQAAGPAGGGEPRTEAVGGEGPREPGAAGGAAGGSRDALSLEEILRLYNQPINEEQAWA 60
Query: 61 VCYQCCGSLRAAARRRQPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQC 120
VCYQCCGSLRAAARRRQPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQC
Sbjct: 61 VCYQCCGSLRAAARRRQPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQC 120
Query: 121 METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG 180
METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG
Sbjct: 121 METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG 180
Query: 181 LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS 240
LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS
Sbjct: 181 LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS 240
Query: 241 AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE 300
AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE
Sbjct: 241 AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE 300
Query: 301 YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK 360
YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK
Sbjct: 301 YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK 360
Query: 361 PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTPESTKN 420
PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTPESTKN
Sbjct: 361 PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTPESTKN 420
Query: 421 LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSS 480
LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSS
Sbjct: 421 LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSS 480
Query: 481 VSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSR 540
VSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSR
Sbjct: 481 VSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSR 540
Query: 541 QSSRSLEEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTR 600
QSSRSLEEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTR
Sbjct: 541 QSSRSLEEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTR 600
Query: 601 RFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPST 660
RFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPST
Sbjct: 601 RFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPST 660
Query: 661 AHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSL 720
AHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSL
Sbjct: 661 AHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSL 720
Query: 721 VLANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI 756
VLANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI
Sbjct: 721 VLANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI 756
>gi|191250771 spire homolog 1 isoform b [Homo sapiens]
Length = 742
Score = 1478 bits (3825), Expect = 0.0
Identities = 742/756 (98%), Positives = 742/756 (98%), Gaps = 14/756 (1%)
Query: 1 MAQAAGPAGGGEPRTEAVGGEGPREPGAAGGAAGGSRDALSLEEILRLYNQPINEEQAWA 60
MAQAAGPAGGGEPRTEAVGGEGPREPGAAGGAAGGSRDALSLEEILRLYNQPINEEQAWA
Sbjct: 1 MAQAAGPAGGGEPRTEAVGGEGPREPGAAGGAAGGSRDALSLEEILRLYNQPINEEQAWA 60
Query: 61 VCYQCCGSLRAAARRRQPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQC 120
VCYQCCGSLRAAARRRQPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQC
Sbjct: 61 VCYQCCGSLRAAARRRQPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQC 120
Query: 121 METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG 180
METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG
Sbjct: 121 METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG 180
Query: 181 LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS 240
LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS
Sbjct: 181 LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS 240
Query: 241 AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE 300
AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE
Sbjct: 241 AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE 300
Query: 301 YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK 360
YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK
Sbjct: 301 YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK 360
Query: 361 PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTPESTKN 420
PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRL DVTTPESTKN
Sbjct: 361 PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRL--------------DVTTPESTKN 406
Query: 421 LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSS 480
LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSS
Sbjct: 407 LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSS 466
Query: 481 VSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSR 540
VSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSR
Sbjct: 467 VSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSR 526
Query: 541 QSSRSLEEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTR 600
QSSRSLEEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTR
Sbjct: 527 QSSRSLEEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTR 586
Query: 601 RFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPST 660
RFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPST
Sbjct: 587 RFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPST 646
Query: 661 AHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSL 720
AHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSL
Sbjct: 647 AHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSL 706
Query: 721 VLANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI 756
VLANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI
Sbjct: 707 VLANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI 742
>gi|191250775 spire homolog 1 isoform c [Homo sapiens]
Length = 622
Score = 1233 bits (3189), Expect = 0.0
Identities = 622/636 (97%), Positives = 622/636 (97%), Gaps = 14/636 (2%)
Query: 121 METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG 180
METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG
Sbjct: 1 METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG 60
Query: 181 LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS 240
LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS
Sbjct: 61 LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS 120
Query: 241 AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE 300
AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE
Sbjct: 121 AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE 180
Query: 301 YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK 360
YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK
Sbjct: 181 YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK 240
Query: 361 PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTPESTKN 420
PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRL DVTTPESTKN
Sbjct: 241 PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRL--------------DVTTPESTKN 286
Query: 421 LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSS 480
LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSS
Sbjct: 287 LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSS 346
Query: 481 VSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSR 540
VSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSR
Sbjct: 347 VSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSR 406
Query: 541 QSSRSLEEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTR 600
QSSRSLEEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTR
Sbjct: 407 QSSRSLEEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTR 466
Query: 601 RFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPST 660
RFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPST
Sbjct: 467 RFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPST 526
Query: 661 AHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSL 720
AHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSL
Sbjct: 527 AHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSL 586
Query: 721 VLANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI 756
VLANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI
Sbjct: 587 VLANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI 622
>gi|55749600 spire homolog 2 [Homo sapiens]
Length = 714
Score = 507 bits (1305), Expect = e-143
Identities = 310/749 (41%), Positives = 429/749 (57%), Gaps = 85/749 (11%)
Query: 27 GAAGGAAGGSRDA----LSLEEILRLYNQPINEEQAWAVCYQCCGSLRAAARRRQPRHRV 82
G+ GGAA G+ LSLEE+L+ Y QP+NEEQAWAVC+Q C LR + P R+
Sbjct: 5 GSCGGAAAGAGRPEPWELSLEEVLKAYEQPLNEEQAWAVCFQGCRGLRGS-----PGRRL 59
Query: 83 RSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQCMETEVIESLGIIIYKALDYGLK 142
R + + DG+V +A EP + L S E + ++SLG IY+ALD+GL
Sbjct: 60 RDTGDLLLRGDGSV--GAREPEAAEPATMVVPLASS---EAQTVQSLGFAIYRALDWGLD 114
Query: 143 ENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEGLGDEDEKRKIS----AIRSYRD 198
E+EERELSP LE+LID MAN + S D G AA+EG G +E+ + ++R++
Sbjct: 115 ESEERELSPQLERLIDLMAN----NDSEDSGCGAADEGYGGPEEEEEAEGVPRSVRTFAQ 170
Query: 199 VMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKSAKENLKKIQEMEKSDESS 258
M+LCAA L A HYQAVCRALF ET+EL FL +++ AKE L+K++E E E+
Sbjct: 171 AMRLCAARLTDPRGAQAHYQAVCRALFVETLELRAFLARVREAKEMLQKLREDEPHLETP 230
Query: 259 -TDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIEYQLTPYEMLMDDIRCKR 317
+L+ L + DWAR WVQ+MR+LR GVKLKKVQE+++NPLP E+QLTP+EMLM DIR +
Sbjct: 231 RAELDSLGHTDWARLWVQLMRELRRGVKLKKVQEQEFNPLPTEFQLTPFEMLMQDIRARN 290
Query: 318 YTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLKPTPPRPRSLHERILEEI 377
Y LRKVMV+GDIPPR+KK AHE+ILDFIRSRPPL VS R+L+P PP+ RSLHE+ILEEI
Sbjct: 291 YKLRKVMVDGDIPPRVKKDAHELILDFIRSRPPLKQVSERRLRPLPPKQRSLHEKILEEI 350
Query: 378 KAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTPESTKNLVESSMVNGGLTSQTKE 437
K ER+LRPV E P L+ + + + + S+ + G ++Q
Sbjct: 351 KQERRLRPVRGEGWAARGFGSLPCI------LNACSGDAKSTSCINLSVTDAGGSAQR-- 402
Query: 438 NGLSTSQQVPAQRKKLLRAPTLAELDSSESEEE--------TLHKSTSSSSVSPSFPEEP 489
+ + LL+APTLAE++ + EE TL + S S +
Sbjct: 403 ----------PRPRVLLKAPTLAEMEEMNTSEEEESPCGEVTLKRDRSFSEHDLAQLRSE 452
Query: 490 VLEAVSTRKKPPKFLPISSTPQPERR-------QPPQRRHSIEKETPTNVRQFLPPSRQS 542
V + + PP T P R +P R + ++ L +R S
Sbjct: 453 VASGLQSATHPP-----GGTEPPRPRAGSAHVWRPGSRDQGTCPASVSDPSHPLLSNRGS 507
Query: 543 SRSLE-------------EFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALK 589
S EF +PVE LALTVEEVM +R+VLVKAE+EK+ Q K+++++LK
Sbjct: 508 SGDRPEASMTPDAKHLWLEFSHPVESLALTVEEVMDVRRVLVKAEMEKFLQNKELFSSLK 567
Query: 590 KGKLCFCCRTRRFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRG 649
KGK+C CCR +F F+W +C FCKR VC+ C KM++PSK + +P+++LG + QR
Sbjct: 568 KGKICCCCRA-KFPLFSWPPSCLFCKRAVCTSCSIKMKMPSKKFGHIPVYTLGFESPQR- 625
Query: 650 ESSMRSEKPSTAHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFI 709
S A P++ F S +S EE FP +VC +C F+
Sbjct: 626 --------VSAAKTAPIQRRDIFQSLQGPQWQSVEE-AFPHIYSHGCVLKDVCSECTSFV 676
Query: 710 SEIISSSRRSLVLANKRARLKRKTQSFYM 738
++++ SSR+S+ + N R R+TQS Y+
Sbjct: 677 ADVVRSSRKSVDVLNTTPRRSRQTQSLYI 705
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 44.7 bits (104), Expect = 3e-04
Identities = 50/194 (25%), Positives = 73/194 (37%), Gaps = 17/194 (8%)
Query: 365 RPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTPESTKNLVES 424
R S ER + ++R+ R S E+++SR++ R S S S S + S + +
Sbjct: 723 RSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRR-SRSLSSPRSKAKSRLSLRRSLSG 781
Query: 425 SMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSSVSPS 484
S SQT S+ +Q K R P SS + K+ S S S S
Sbjct: 782 SSPCPKQKSQTPPR---RSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSS 838
Query: 485 FPEEPVLEAVSTRK-------------KPPKFLPISSTPQPERRQPPQRRHSIEKETPTN 531
P V R+ P + S+P PE + RHS +P
Sbjct: 839 SPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPR 898
Query: 532 VRQFLPPSRQSSRS 545
V+ PP + SRS
Sbjct: 899 VKSSTPPRQSPSRS 912
Score = 34.3 bits (77), Expect = 0.44
Identities = 47/200 (23%), Positives = 68/200 (34%), Gaps = 16/200 (8%)
Query: 346 RSRPPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSY 405
RSR +P + R+ + P R + R+ R + RRSR P+S
Sbjct: 1863 RSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRR 1922
Query: 406 SFDLSDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSS 465
S TP T+ S T T+ S + V +R + P S
Sbjct: 1923 SRS----RTPPVTRRRSRSR------TPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRS 1972
Query: 466 ESEEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIE 525
+ T +S S +S V+ R+ + P++ R P RR S
Sbjct: 1973 RTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRS-R 2031
Query: 526 KETPTNVRQFLPPSRQSSRS 545
TP LP R SRS
Sbjct: 2032 SRTP-----LLPRKRSRSRS 2046
Score = 32.3 bits (72), Expect = 1.7
Identities = 60/235 (25%), Positives = 86/235 (36%), Gaps = 20/235 (8%)
Query: 331 PRLKKSAHEII--------LDFIRSR-PPLNPVSARKLKPTPPRPRS-LHERILEEIKAE 380
PR+ SA+E + LD RSR PP P +R P P S + + + +
Sbjct: 2383 PRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPP 2442
Query: 381 RKLRPVSP------EEIRRSRLAMRPLSMSYSFDLSDVTTPESTK---NLVESSMVNGGL 431
+ +P SP ++ R P++ S S V T S+ N + S G
Sbjct: 2443 AQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVP 2502
Query: 432 TSQTKENGLSTSQQVPAQRKKLLRAPTL-AELDSSESEEETLHKSTSSSSVSPSFPEEPV 490
S E ST Q P+ L A + SS S + S+SSSS S S
Sbjct: 2503 HSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSD 2562
Query: 491 LEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSRQSSRS 545
E S +P L +P P ++ + E R+ S SS S
Sbjct: 2563 SEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSS 2617
Score = 32.3 bits (72), Expect = 1.7
Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 12/105 (11%)
Query: 444 QQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSS--SVSPSFPEEPVLEAVSTRKKPP 501
+ PA+RK+ + + + SS S + S+SSS S S S + S K P
Sbjct: 2597 EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGP 2656
Query: 502 KFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSRQSSRSL 546
+ LP ++P ++ PP R S P + S + SRSL
Sbjct: 2657 QALPKPASP---KKPPPGERRSRSPRKPID-------SLRDSRSL 2691
Score = 32.0 bits (71), Expect = 2.2
Identities = 38/171 (22%), Positives = 65/171 (38%), Gaps = 13/171 (7%)
Query: 380 ERKLRPVSPEEIRRSRLAMRPLSMSYS---FDLSDVTTPESTKNLVESSMVNGGLTSQTK 436
ER SP+ ++R +R S S S D +P +++ + + +
Sbjct: 1555 ERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRA 1614
Query: 437 ENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSSVSPSFPEEPVLEAVST 496
++G +S + A + L P + SS + +SS+ SP P + +
Sbjct: 1615 QSGSDSSPEPKAPAPRAL--PRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGS 1672
Query: 497 RKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSRQSSRSLE 547
R P P+ + R PP+RR S T + SR +S S E
Sbjct: 1673 RSSPE--------PKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPE 1715
Score = 32.0 bits (71), Expect = 2.2
Identities = 49/217 (22%), Positives = 78/217 (35%), Gaps = 19/217 (8%)
Query: 330 PPRLKKSAHEIILDFIRSRPPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPE 389
P R + + + D R+ P S +P P PR+L R + K R SPE
Sbjct: 1593 PRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRR--SRSGSSSKGRGPSPE 1650
Query: 390 EIRRSRLAMRPLSMSYSFDLSDVTTPES-TKNLVESSMVNGGLTSQTKENGLSTSQQVPA 448
S S + S P+S T S S+T S+
Sbjct: 1651 G-------------SSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPEL 1697
Query: 449 QRKKLLRAPTLAELDSSESEEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISS 508
RK L + + S E+ T + S SVS EP ++ S+R++ P +
Sbjct: 1698 TRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSP---EPAEKSRSSRRRRSASSPRTK 1754
Query: 509 TPQPERRQPPQRRHSIEKETPTNVRQFLPPSRQSSRS 545
T R P + +++ + R+ +R+ RS
Sbjct: 1755 TTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRS 1791
Score = 32.0 bits (71), Expect = 2.2
Identities = 30/129 (23%), Positives = 52/129 (40%), Gaps = 16/129 (12%)
Query: 433 SQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSSVSPSFPEEPVLE 492
++ K S+S + + + + SS S + S+SSSS SP+ P L
Sbjct: 2601 AKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALP 2660
Query: 493 AVSTRKKPPKFLPISSTPQP----------------ERRQPPQRRHSIEKETPTNVRQFL 536
++ KKPP S +P+ ERR+P + ++++ ++ R
Sbjct: 2661 KPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSR 2720
Query: 537 PPSRQSSRS 545
R SRS
Sbjct: 2721 RGQRGDSRS 2729
Score = 31.2 bits (69), Expect = 3.7
Identities = 38/186 (20%), Positives = 70/186 (37%), Gaps = 11/186 (5%)
Query: 365 RPRSLHERILEEIKAERKLRPVSPEEI---RRSRLAMRPLSMSYSFDLSDVTTPESTKNL 421
RP E L ++A RP +P+ + R+ R+ +R L + + +
Sbjct: 33 RPDYKGEEELRRLEAALVKRP-NPDILDHERKRRVELRCLELEEMMEEQGYEEQQ----- 86
Query: 422 VESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSSV 481
++ + L K+ ++ P QR + LAEL+ ++E S S V
Sbjct: 87 IQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYV 146
Query: 482 SPSF--PEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPS 539
S P+ EA +PPK + R P+++ +K+ + P
Sbjct: 147 DGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPR 206
Query: 540 RQSSRS 545
R+ +S
Sbjct: 207 RERKKS 212
Score = 30.8 bits (68), Expect = 4.9
Identities = 51/211 (24%), Positives = 78/211 (36%), Gaps = 36/211 (17%)
Query: 346 RSRPPLNPVSARKLKP-TPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMS 404
RSR +PVS R+ + TPP R R+ R +P RRSR P++
Sbjct: 1910 RSRSRASPVSRRRSRSRTPPVTR-------------RRSRSRTPTTRRRSRSRTPPVTRR 1956
Query: 405 YSFDLSDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDS 464
S TP T+ S + T+ S + V +R + +P
Sbjct: 1957 RSRS----RTPPVTRRRSRSR-----TSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSR 2007
Query: 465 SESEEETLHKSTSSSSVS---PSFPEEPVLEAVSTRKKPPKFL---PISSTPQPER---- 514
S + T +S S + + S P+L +R + P + S TP+ R
Sbjct: 2008 SRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRS 2067
Query: 515 --RQPPQ-RRHSIEKETPTNVRQFLPPSRQS 542
R PP RR S + R PP+ ++
Sbjct: 2068 LTRSPPAIRRRSASGSSSDRSRSATPPATRN 2098
>gi|61966703 NHS-like 2 [Homo sapiens]
Length = 709
Score = 44.7 bits (104), Expect = 3e-04
Identities = 61/225 (27%), Positives = 92/225 (40%), Gaps = 33/225 (14%)
Query: 350 PLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPE------------EIRRSRLA 397
P + S++ PTP SL L + ++RPV PE + +SRL+
Sbjct: 345 PSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLS 404
Query: 398 MR-PLSMSYSFDLSDVTTPESTKNLVES--SMVNGGLTSQTKENGLSTSQQVPAQRKKLL 454
PL+ S + DLS ++ +K V S N G+ K N +P + L
Sbjct: 405 FDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTN--PNQPIMPMVTQSDL 462
Query: 455 RAPTLAELDSSESEEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPER 514
R+ L + SE E++ SP + EEP E V T + P++ P P
Sbjct: 463 RSVRLRSVSKSEPEDDI---------ESPEYAEEPRAEEVFTLPERKTKPPVAEKP-PVA 512
Query: 515 RQPPQRRHS----IEKETPTNVRQFLPP--SRQSSRSLEEFCYPV 553
R+PP H E+ T+ +PP S Q +R L + Y V
Sbjct: 513 RRPPSLVHKPPSVPEEYALTSPTLAMPPRSSIQHARPLPQDSYTV 557
>gi|116268127 kinase non-catalytic C-lobe domain (KIND) containing 1
isoform a [Homo sapiens]
Length = 1749
Score = 43.9 bits (102), Expect = 6e-04
Identities = 34/121 (28%), Positives = 54/121 (44%)
Query: 40 LSLEEILRLYNQPINEEQAWAVCYQCCGSLRAAARRRQPRHRVRSAAQIRVWRDGAVTLA 99
+SL +IL L ++ ++E++AWAVC +C S+R+ A + + + G V
Sbjct: 37 VSLADILSLRDRGLSEQEAWAVCLECSLSMRSVAHAAIFQSLCITPDTLAFNTSGNVCFM 96
Query: 100 PAADDAGEPPPVAGKLGYSQCMETEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDH 159
D E V + + I SLG + AL+Y + E LS LE L+
Sbjct: 97 EQLSDDPEGAFVPPEFDVTGNTFEAHIYSLGATLKAALEYVAEPTLEPRLSQDLEALLSR 156
Query: 160 M 160
M
Sbjct: 157 M 157
Score = 38.1 bits (87), Expect = 0.030
Identities = 41/179 (22%), Positives = 71/179 (39%), Gaps = 29/179 (16%)
Query: 7 PAGGGEPRTEAVG---GEGPREPGAAGGAAGGSRDA------------------LSLEEI 45
P G+P T E P +P A G A RD +SL+++
Sbjct: 390 PGSPGQPETSHPSQGPAEAPADPRDASGEAQTPRDDERIPEGARQLESAAAEQWVSLQDL 449
Query: 46 LRLYNQPINEEQAWAVCYQCCGSLRAAARRRQPRHRVRSAA-QIRVWRDGAVTL-APAAD 103
L +P E + WA+C C +L+ +P H + V DGAV P A+
Sbjct: 450 LSQLGRPFREYELWALCLACLRALQT-----RPEHPAYLCLDSVLVAEDGAVLFQPPPAN 504
Query: 104 DAGEPPPVAGKLGYSQCM-ETEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMA 161
+ + +A +L + + E + + +++ A + + N + L L+ L+ MA
Sbjct: 505 GSYDSFFLAPELAEERLVTEKASVYCVAAVLWTAAKFSVPRNHKLALPRRLKTLLLDMA 563
>gi|51871374 UTP14, U3 small nucleolar ribonucleoprotein, homolog C
[Homo sapiens]
Length = 766
Score = 43.1 bits (100), Expect = 0.001
Identities = 84/394 (21%), Positives = 152/394 (38%), Gaps = 37/394 (9%)
Query: 201 KLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKSAKENLKKIQEMEKSDESSTD 260
K+ A L ++Y+A R + + + K AK+ LK+ ++++K + +
Sbjct: 220 KMHRAELQRARALQSYYEAKARKEKKIKSKKYHKVVKKGKAKKALKEFEQLQKVNPTVA- 278
Query: 261 LEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIEYQLTPYEMLMDDIRCKRYTL 320
LEE++ + AR ++ +N K K + + +Y L + + + + +
Sbjct: 279 LEEMEKIENARMMERMSLKHQNSGKWAKSKA-----IMAKYDLEARQAMQEQLAKNKELT 333
Query: 321 RKVMVNGDIPPRLKKS-AHEIILDFIRSRPPLNP-----------VSARKLKPTPPRPRS 368
+K+ V + + E+++ + + +N S K T P
Sbjct: 334 QKLQVASESEEEEGGTEVEELLVPHVANEVQMNVDGPNPWMFRSCTSDTKEAATQEDPEQ 393
Query: 369 LHERILEEIKA-ERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTPESTKNLVESSMV 427
+ E E+ A E + RPV+ EEI R S+ +L+ P S++ +SS
Sbjct: 394 VPELAAHEVSASEAEERPVAEEEILLREFEERQ-SLRKRSELNQDAEPASSQETKDSSSQ 452
Query: 428 N-----GGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSSVS 482
L+ + KE S Q+ ++ P + + + E E L S +
Sbjct: 453 EVLSELRALSQKLKEKHQSRKQKASSEGT----VPQVQREEPAPEEAEPLLLQRSERVQT 508
Query: 483 PSFPEEPVLEAVSTRKKPPKFLPISSTPQPER---RQPPQRRHSIEKETPTNVRQFLPPS 539
EE E K+ P+ P+ Q ER +P + EKE N++ FL
Sbjct: 509 LEELEELGKEDCFQNKELPR--PVLEGQQSERTPNNRPDAPKEKKEKEQLINLQNFLTTQ 566
Query: 540 RQSSRSLEEFCYPVECLALTVEEVMHIRQVLVKA 573
S RSL P L EE RQ++ +A
Sbjct: 567 SPSVRSL---AVPTIIEELEDEEERDQRQMIKEA 597
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 40.0 bits (92), Expect = 0.008
Identities = 61/266 (22%), Positives = 98/266 (36%), Gaps = 40/266 (15%)
Query: 288 KVQERQYNPLPIEYQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRS 347
+ + R +P P + + TP E+ ++ K ++++ DI LK E I +
Sbjct: 204 RTKSRSPSPAPEKKEKTP-ELPEPSVKVKEPSVQEATSTSDI---LKVPKPEPIPEPKEP 259
Query: 348 RPPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSF 407
P N ++ + T PR RS K+ + R SP R R R S S S+
Sbjct: 260 SPEKNSKKEKEKEKTRPRSRS-------RSKSRSRTRSRSPSHTRPRR---RHRSRSRSY 309
Query: 408 DLSDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSES 467
+P + + P R + R+P SS S
Sbjct: 310 SPRRRPSPRRRPS---------------PRRRTPPRRMPPPPRHRRSRSPVRRRRRSSAS 354
Query: 468 EEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQ------PERRQPPQRR 521
+ S+SS S SP P++P S +K + P +S P+ P PP+ R
Sbjct: 355 LSGSSSSSSSSRSRSP--PKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTR 412
Query: 522 HSIEKETPTNVRQ---FLPPSRQSSR 544
HS + R+ + P R S +
Sbjct: 413 HSPTPQQSNRTRKSRVSVSPGRTSGK 438
Score = 32.7 bits (73), Expect = 1.3
Identities = 43/191 (22%), Positives = 74/191 (38%), Gaps = 14/191 (7%)
Query: 357 RKLKPTP-PRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTP 415
++ P+P P+PR + L E + ++ + + + +++ R R S S S ++
Sbjct: 447 KRESPSPAPKPRKVE---LSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSE 503
Query: 416 ESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKS 475
+ + S V G + + + S S P+ RK+ S S T +
Sbjct: 504 DERP---KRSHVKNGEVGRRRRHSPSRSAS-PSPRKRQKETSPRGRRRRSPSPPPTRRRR 559
Query: 476 TSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPP-QRRHSIEKETPTNVRQ 534
+ S + P P R++ P P +P P R PP QRR+S P R
Sbjct: 560 SPSPAPPPRRRRTPT---PPPRRRTPSPPPRRRSPSPRRYSPPIQRRYS--PSPPPKRRT 614
Query: 535 FLPPSRQSSRS 545
PP R+
Sbjct: 615 ASPPPPPKRRA 625
Score = 31.2 bits (69), Expect = 3.7
Identities = 38/178 (21%), Positives = 64/178 (35%), Gaps = 8/178 (4%)
Query: 375 EEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFD-------LSDVTTPESTKNLVESSMV 427
E ++ R+ + SP RRS R S+S S PE + E
Sbjct: 167 ERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEP 226
Query: 428 NGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSSVSPSFPE 487
+ + + + STS + + + + P + + +E+ K+ S
Sbjct: 227 SVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRS 286
Query: 488 EPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSRQSSRS 545
+ S + + S + P RR P+RR S + TP R PP + SRS
Sbjct: 287 RTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPR-RMPPPPRHRRSRS 343
Score = 30.8 bits (68), Expect = 4.9
Identities = 45/220 (20%), Positives = 79/220 (35%), Gaps = 19/220 (8%)
Query: 330 PPRLKKSAHEIILDFIRSRPPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPE 389
PPR + + I+ R +P R+ PP P+ R +R++ P
Sbjct: 585 PPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPK---RRASPSPPPKRRVSHSPPP 641
Query: 390 EIRRSRLAMRPLSMSYSFDLSDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQ 449
+ R S + R S S S ++P + S N + + TS P
Sbjct: 642 KQRSSPVTKRR-SPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPV 700
Query: 450 RKKLLRAPTLAELDSSESE-----EETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFL 504
R+ +P + S + T + SPS + V S+R
Sbjct: 701 RRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS--PQSVRRVSSSRS------ 752
Query: 505 PISSTPQPERRQPPQRRHSIEKETP-TNVRQFLPPSRQSS 543
+S +P+P ++PP ++ ++P TN +P + S
Sbjct: 753 -VSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKS 791
>gi|61966919 hypothetical protein LOC442444 [Homo sapiens]
Length = 1035
Score = 39.3 bits (90), Expect = 0.014
Identities = 56/211 (26%), Positives = 71/211 (33%), Gaps = 20/211 (9%)
Query: 345 IRSRPPLNP-VSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSM 403
+ S PP P L P PP R H R LRP P + R L P +
Sbjct: 591 VSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRP-EPPKTRMYSLRPEPPNT 649
Query: 404 SYSFDLSDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELD 463
S PE K V S L + E G+S P + + P E
Sbjct: 650 GVSH-----LCPEPPKTRVSS------LPPEPPETGVSHLCPEPPETRVSHLRPEPPETG 698
Query: 464 SSESEEE-------TLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQ 516
S E +LH S VS PE P R +PPK S P+P +
Sbjct: 699 VSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLETR 758
Query: 517 PPQRRHSIEKETPTNVRQFLPPSRQSSRSLE 547
R + +++ LP R SS LE
Sbjct: 759 VSHLRPEPPETGVSHLHPELPKPRVSSLHLE 789
Score = 38.1 bits (87), Expect = 0.030
Identities = 57/215 (26%), Positives = 78/215 (36%), Gaps = 29/215 (13%)
Query: 345 IRSRPPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMS 404
+RS PP VS L+P P+ R H R LRP P + R S L + P
Sbjct: 414 LRSEPPKIGVSHLCLEP--PKTRGSHLRPEPPETGVSHLRP-EPPKTRVSSLHLEPPETG 470
Query: 405 YSFDLSDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDS 464
S PE + V L + + G+S P + + P +E
Sbjct: 471 VSH-----LCPEPPEKDVSH------LRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGV 519
Query: 465 SESEEE-------TLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERR-- 515
S E +LH++ SSVS PE P R +PPK S P+P
Sbjct: 520 SHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGV 579
Query: 516 -----QPPQRR-HSIEKETPTNVRQFLPPSRQSSR 544
+PP+ R S+ E P L P +R
Sbjct: 580 SHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETR 614
Score = 35.8 bits (81), Expect = 0.15
Identities = 54/208 (25%), Positives = 78/208 (37%), Gaps = 25/208 (12%)
Query: 349 PPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPV--SPEEIRRSRLAMRPLSMSYS 406
PP VS L P PP+ R H L E + + P + R S L P S
Sbjct: 274 PPGTGVS--HLCPEPPKTRVSH---LHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVS 328
Query: 407 FDLSDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRK--KLLRAPTLAEL-- 462
PE K LV S L + E G+S P + + L + P A +
Sbjct: 329 H-----LHPEPPKTLVSS------LHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSH 377
Query: 463 ---DSSESEEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQ 519
+ ++ L T + VSP FPE P + R +PPK +P + +
Sbjct: 378 LCPEPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSH 437
Query: 520 RRHSIEKETPTNVRQFLPPSRQSSRSLE 547
R + +++R P +R SS LE
Sbjct: 438 LRPEPPETGVSHLRPEPPKTRVSSLHLE 465
Score = 30.4 bits (67), Expect = 6.3
Identities = 49/207 (23%), Positives = 70/207 (33%), Gaps = 37/207 (17%)
Query: 345 IRSRPPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMS 404
+R PP VS L P PP+ R H R LRP P +I S L P
Sbjct: 486 LRPEPPDTGVS--HLCPEPPKTRVSHLRPEPSETGVSHLRP-EPPKILVSSLHQAP---- 538
Query: 405 YSFDLSDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDS 464
PES+ + L + E G+S + P + + P +
Sbjct: 539 ----------PESSVS---------HLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGV 579
Query: 465 S-------ESEEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQP 517
S ++ +L + VS PE P R +PP+ P+P P
Sbjct: 580 SHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEP----P 635
Query: 518 PQRRHSIEKETPTNVRQFLPPSRQSSR 544
R +S+ E P L P +R
Sbjct: 636 KTRMYSLRPEPPNTGVSHLCPEPPKTR 662
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 38.9 bits (89), Expect = 0.018
Identities = 71/338 (21%), Positives = 120/338 (35%), Gaps = 68/338 (20%)
Query: 222 RALFAETMELHTFLTKIKSAKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLR 281
R L A T EL +KS K++L++ Q E D D+ + A Q+ +LR
Sbjct: 323 RQLQARTTELEA----LKSTKDSLER-QRSELEDRHQADIASYQEAIQ-----QLDAELR 372
Query: 282 NGVKLKKVQERQYNPL-----PIEYQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKS 336
N Q R+Y L ++ ++ Y L++ C+ + G IP L +
Sbjct: 373 NTKWEMAAQLREYQDLLNVKMALDIEIAAYRKLLEGEECR-------IGFGPIPFSLPEG 425
Query: 337 AHEIILDFIRSRPPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRL 396
+I P + +K +K+E K++ V E +
Sbjct: 426 LPKI------------PSVSTHIK----------------VKSEEKIKVVEKSEKETVIV 457
Query: 397 AMRPLSMSYSFDLSDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRA 456
+ + +VT E + E G + E G ++ PA+
Sbjct: 458 EEQTEETQVT---EEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAE------- 507
Query: 457 PTLAELDSSESEEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQ 516
E S E E ++ K + S PE+ ++ + K P K + +P E +
Sbjct: 508 ----EAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEK----AKSPAKEEAK 559
Query: 517 PPQRRHSIEKETPTNVRQFLPPSRQSSRSLEEFCYPVE 554
P S EKE + + P + S + EE P E
Sbjct: 560 SPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAE 597
Score = 35.8 bits (81), Expect = 0.15
Identities = 41/187 (21%), Positives = 75/187 (40%), Gaps = 16/187 (8%)
Query: 376 EIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTPESTKNLV-ESSMVNGGLTSQ 434
E K+ K SP E++ A P + + ++ +PE K+ V E + S
Sbjct: 563 EAKSPEKEEAKSPAEVKSPEKAKSP-AKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSP 621
Query: 435 TKENGLSTSQQVPAQRKKLLRAPTLAELDSSES-------EEETLHKSTSSSSVSPSFPE 487
KE S ++ ++ K +PT E S E E ++ K+ S PE
Sbjct: 622 VKEEAKSPAEVKSPEKAK---SPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPE 678
Query: 488 EPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSRQSSRSLE 547
+ + K P K + +P E + P++ S KE + + P ++ +++ E
Sbjct: 679 KAKSPVKAEAKSPEK----AKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPE 734
Query: 548 EFCYPVE 554
+ PV+
Sbjct: 735 KAKSPVK 741
Score = 33.5 bits (75), Expect = 0.75
Identities = 31/156 (19%), Positives = 62/156 (39%), Gaps = 7/156 (4%)
Query: 410 SDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEE 469
++V +PE K+ + + ++ + +V + K A A+ +
Sbjct: 542 AEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSP 601
Query: 470 ETLHKSTSSSSVSPSFPEEPVLEAVSTR---KKPPKFLPISSTPQPERRQPPQRRHSIEK 526
E + SP+ + PV E + K P K + +P E + P++ S EK
Sbjct: 602 EKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEK----AKSPTKEEAKSPEKAKSPEK 657
Query: 527 ETPTNVRQFLPPSRQSSRSLEEFCYPVECLALTVEE 562
E + + P + ++S E+ PV+ A + E+
Sbjct: 658 EEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEK 693
Score = 32.0 bits (71), Expect = 2.2
Identities = 44/235 (18%), Positives = 89/235 (37%), Gaps = 12/235 (5%)
Query: 352 NPVSARKLKPTPPR-PRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLS 410
+PV P + P EE K+ K + EE + A P+ +
Sbjct: 620 SPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVK-------A 672
Query: 411 DVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEE 470
+ +PE K+ V++ + + + ++ + K+ ++P A+ E E +
Sbjct: 673 EAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKE-EAK 731
Query: 471 TLHKSTS---SSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKE 527
T K+ S + SP + P K P P + + P++ S KE
Sbjct: 732 TPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKE 791
Query: 528 TPTNVRQFLPPSRQSSRSLEEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYK 582
+ + P ++ +++ E+ E + V+E ++V VK +K ++ K
Sbjct: 792 EVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEK 846
>gi|68508961 centromere protein C 1 [Homo sapiens]
Length = 943
Score = 37.7 bits (86), Expect = 0.040
Identities = 45/191 (23%), Positives = 84/191 (43%), Gaps = 24/191 (12%)
Query: 373 ILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTPESTKNLVESSMVNGGLT 432
+L+ K+ K + P+ + + + +P + S SD T +++ L+ ++ N
Sbjct: 340 LLQGRKSREKHHNILPKTLANDKHSHKPHPVETS-QPSDKTVLDTSYALIGETVNN---Y 395
Query: 433 SQTKENGLSTSQQVPA---------QRKKLLRAPTLAELDSSESEEETLHKS-------T 476
TK S + + P+ QR+K + P +LD +S++E +H S
Sbjct: 396 RSTKYEMYSKNAEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQ 455
Query: 477 SSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIE---KETPTNVR 533
+S + EE + VS ++ PP SST + ++ + ++R S E K P V
Sbjct: 456 RNSDRNMEEHEEMGNDCVSKKQMPPVGSKKSST-RKDKEESKKKRFSSESKNKLVPEEVT 514
Query: 534 QFLPPSRQSSR 544
+ SR+ SR
Sbjct: 515 STVTKSRRISR 525
>gi|238624188 diffuse panbronchiolitis critical region 1 protein
[Homo sapiens]
Length = 1393
Score = 37.4 bits (85), Expect = 0.052
Identities = 39/192 (20%), Positives = 70/192 (36%), Gaps = 7/192 (3%)
Query: 353 PVSARKLKPTPPRPRSLHERILEEIKAERKLRPV-SPEEIRRSRLAMRPLSMSYSFDLSD 411
P++ +P P ER E P + E P + + D +
Sbjct: 708 PLANENTTLSPAEPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTP 767
Query: 412 VTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEET 471
+ ++T +L E + NG T E S+S + P + + R P E +S E T
Sbjct: 768 LANEKTTPSLAEPTE-NGKRTPFANEKTTSSSAE-PTEHAE--RTPLANENTTSSPAEPT 823
Query: 472 LHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTN 531
++ +++ + FP EP ST + K P + P R ++ PT
Sbjct: 824 ENRERTANEKTTQFPAEPTENRESTANE--KTTPFPAEPTENREWTANENTTLSPAEPTE 881
Query: 532 VRQFLPPSRQSS 543
+ P + + +
Sbjct: 882 HEEMTPLANEKT 893
Score = 32.7 bits (73), Expect = 1.3
Identities = 45/182 (24%), Positives = 77/182 (42%), Gaps = 25/182 (13%)
Query: 353 PVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEI-RRSRLAMRPLSMS------- 404
P + K P+P +P HE + PV P E ++ LA +++S
Sbjct: 1028 PSANEKTIPSPAKPTE-HEEMTPSANENTTPSPVKPTEHGEKTTLANEKITLSPEGPTEH 1086
Query: 405 --YSFDLSDVTTP---ESTKNLVESSMVNGGLTSQ----TKENGLSTSQQV----PAQRK 451
+ ++ TP + T++ ++ N +TS T+ +TS V PA+
Sbjct: 1087 GAKTTSANEKITPSLAKPTEHGERTTSPNDKITSSAAESTEHRDRATSANVITPAPAEPI 1146
Query: 452 KLLRAPTLA-ELDSSESEEETLH--KSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISS 508
K + TLA E + +E+ T H K+TS++ + PE+P L + T K P+
Sbjct: 1147 KHAKRTTLAHEKMTQVTEKSTEHPEKTTSTTEKTTRTPEKPTLYSEKTICTKGKNTPVPE 1206
Query: 509 TP 510
P
Sbjct: 1207 KP 1208
>gi|24497609 nucleoporin 62kDa [Homo sapiens]
Length = 522
Score = 37.4 bits (85), Expect = 0.052
Identities = 55/226 (24%), Positives = 92/226 (40%), Gaps = 50/226 (22%)
Query: 8 AGGGEPRTEAVGGEGPREPGAAGGAAGGSRDALSLEEILRLYNQPINEEQAWAVCYQCCG 67
A G P A P PGAA GAA S A++ ++ L N+ W++
Sbjct: 298 APAGIPSNTAAAVTAPPGPGAAAGAAASS--AMTYAQLESLINK-------WSL------ 342
Query: 68 SLRAAARRRQPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQCMETEVIE 127
Q RH ++ A Q+ W + G+ S E E ++
Sbjct: 343 -----ELEDQERHFLQQATQVNAWDRTLIE--------------NGEKITSLHREVEKVK 383
Query: 128 SLGIIIYKALDYGLKENEERE-LSPPLEQLIDHMANTV---EADGSNDEGYEAAEEGLGD 183
+ + LD+ L + +E E L PLE+L+ + T+ AD ++ Y+ AE +
Sbjct: 384 LDQKRLDQELDFILSQQKELEDLLSPLEELVKEQSGTIYLQHADEEREKTYKLAE----N 439
Query: 184 EDEKRKISAIRSYRDVMKLCAAHLPTE---SDAPNHYQAVCRALFA 226
D + K A + +D+++ HL T +D + Q +C+ L A
Sbjct: 440 IDAQLKRMA-QDLKDIIE----HLNTSGAPADTSDPLQQICKILNA 480
>gi|24497607 nucleoporin 62kDa [Homo sapiens]
Length = 522
Score = 37.4 bits (85), Expect = 0.052
Identities = 55/226 (24%), Positives = 92/226 (40%), Gaps = 50/226 (22%)
Query: 8 AGGGEPRTEAVGGEGPREPGAAGGAAGGSRDALSLEEILRLYNQPINEEQAWAVCYQCCG 67
A G P A P PGAA GAA S A++ ++ L N+ W++
Sbjct: 298 APAGIPSNTAAAVTAPPGPGAAAGAAASS--AMTYAQLESLINK-------WSL------ 342
Query: 68 SLRAAARRRQPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQCMETEVIE 127
Q RH ++ A Q+ W + G+ S E E ++
Sbjct: 343 -----ELEDQERHFLQQATQVNAWDRTLIE--------------NGEKITSLHREVEKVK 383
Query: 128 SLGIIIYKALDYGLKENEERE-LSPPLEQLIDHMANTV---EADGSNDEGYEAAEEGLGD 183
+ + LD+ L + +E E L PLE+L+ + T+ AD ++ Y+ AE +
Sbjct: 384 LDQKRLDQELDFILSQQKELEDLLSPLEELVKEQSGTIYLQHADEEREKTYKLAE----N 439
Query: 184 EDEKRKISAIRSYRDVMKLCAAHLPTE---SDAPNHYQAVCRALFA 226
D + K A + +D+++ HL T +D + Q +C+ L A
Sbjct: 440 IDAQLKRMA-QDLKDIIE----HLNTSGAPADTSDPLQQICKILNA 480
>gi|24497605 nucleoporin 62kDa [Homo sapiens]
Length = 522
Score = 37.4 bits (85), Expect = 0.052
Identities = 55/226 (24%), Positives = 92/226 (40%), Gaps = 50/226 (22%)
Query: 8 AGGGEPRTEAVGGEGPREPGAAGGAAGGSRDALSLEEILRLYNQPINEEQAWAVCYQCCG 67
A G P A P PGAA GAA S A++ ++ L N+ W++
Sbjct: 298 APAGIPSNTAAAVTAPPGPGAAAGAAASS--AMTYAQLESLINK-------WSL------ 342
Query: 68 SLRAAARRRQPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQCMETEVIE 127
Q RH ++ A Q+ W + G+ S E E ++
Sbjct: 343 -----ELEDQERHFLQQATQVNAWDRTLIE--------------NGEKITSLHREVEKVK 383
Query: 128 SLGIIIYKALDYGLKENEERE-LSPPLEQLIDHMANTV---EADGSNDEGYEAAEEGLGD 183
+ + LD+ L + +E E L PLE+L+ + T+ AD ++ Y+ AE +
Sbjct: 384 LDQKRLDQELDFILSQQKELEDLLSPLEELVKEQSGTIYLQHADEEREKTYKLAE----N 439
Query: 184 EDEKRKISAIRSYRDVMKLCAAHLPTE---SDAPNHYQAVCRALFA 226
D + K A + +D+++ HL T +D + Q +C+ L A
Sbjct: 440 IDAQLKRMA-QDLKDIIE----HLNTSGAPADTSDPLQQICKILNA 480
>gi|24497603 nucleoporin 62kDa [Homo sapiens]
Length = 522
Score = 37.4 bits (85), Expect = 0.052
Identities = 55/226 (24%), Positives = 92/226 (40%), Gaps = 50/226 (22%)
Query: 8 AGGGEPRTEAVGGEGPREPGAAGGAAGGSRDALSLEEILRLYNQPINEEQAWAVCYQCCG 67
A G P A P PGAA GAA S A++ ++ L N+ W++
Sbjct: 298 APAGIPSNTAAAVTAPPGPGAAAGAAASS--AMTYAQLESLINK-------WSL------ 342
Query: 68 SLRAAARRRQPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQCMETEVIE 127
Q RH ++ A Q+ W + G+ S E E ++
Sbjct: 343 -----ELEDQERHFLQQATQVNAWDRTLIE--------------NGEKITSLHREVEKVK 383
Query: 128 SLGIIIYKALDYGLKENEERE-LSPPLEQLIDHMANTV---EADGSNDEGYEAAEEGLGD 183
+ + LD+ L + +E E L PLE+L+ + T+ AD ++ Y+ AE +
Sbjct: 384 LDQKRLDQELDFILSQQKELEDLLSPLEELVKEQSGTIYLQHADEEREKTYKLAE----N 439
Query: 184 EDEKRKISAIRSYRDVMKLCAAHLPTE---SDAPNHYQAVCRALFA 226
D + K A + +D+++ HL T +D + Q +C+ L A
Sbjct: 440 IDAQLKRMA-QDLKDIIE----HLNTSGAPADTSDPLQQICKILNA 480
>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
Length = 2089
Score = 36.6 bits (83), Expect = 0.089
Identities = 38/181 (20%), Positives = 67/181 (37%), Gaps = 2/181 (1%)
Query: 349 PPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFD 408
PPL +KPT + R + E +L P P+ R+R + R +
Sbjct: 1064 PPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSA 1123
Query: 409 LSDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESE 468
+ ST V + S+T + + T + V +L + + + +SE
Sbjct: 1124 APEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPT 1183
Query: 469 EETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKET 528
+ S SSV PE V A+ + P++S P + + + R S++
Sbjct: 1184 SQVTRGRKSRSSVKT--PETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPE 1241
Query: 529 P 529
P
Sbjct: 1242 P 1242
>gi|239751395 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 306
Score = 36.6 bits (83), Expect = 0.089
Identities = 49/188 (26%), Positives = 65/188 (34%), Gaps = 14/188 (7%)
Query: 347 SRPPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYS 406
S P L P S L P P RS + L P SP + S S + +
Sbjct: 70 STPTLTPSSTPTLTPQPILTRS----------STPTLTPSSPPTLTPSNTPTLTPSNTPT 119
Query: 407 FDLSDVTT--PESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRA--PTLAEL 462
S+ T P ST L SS +S+ ST P+ R L R+ PTL
Sbjct: 120 LTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPS 179
Query: 463 DSSESEEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRH 522
+ + T SS+ + + P+L ST P PI + P R
Sbjct: 180 STPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPI 239
Query: 523 SIEKETPT 530
TPT
Sbjct: 240 LTRSSTPT 247
>gi|239745904 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 306
Score = 36.6 bits (83), Expect = 0.089
Identities = 49/188 (26%), Positives = 65/188 (34%), Gaps = 14/188 (7%)
Query: 347 SRPPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYS 406
S P L P S L P P RS + L P SP + S S + +
Sbjct: 70 STPTLTPSSTPTLTPQPILTRS----------STPTLTPSSPPTLTPSNTPTLTPSNTPT 119
Query: 407 FDLSDVTT--PESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRA--PTLAEL 462
S+ T P ST L SS +S+ ST P+ R L R+ PTL
Sbjct: 120 LTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPS 179
Query: 463 DSSESEEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRH 522
+ + T SS+ + + P+L ST P PI + P R
Sbjct: 180 STPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPI 239
Query: 523 SIEKETPT 530
TPT
Sbjct: 240 LTRSSTPT 247
>gi|6005830 plakophilin 3 [Homo sapiens]
Length = 797
Score = 36.6 bits (83), Expect = 0.089
Identities = 36/142 (25%), Positives = 53/142 (37%), Gaps = 10/142 (7%)
Query: 356 ARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTP 415
A+ P P RP S HER +A+ +R RL L YS +S+ P
Sbjct: 151 AQPTPPMPTRPVSFHERGGVGSRAD-----YDTLSLRSLRLGPGGLDDRYSL-VSEQLEP 204
Query: 416 ESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKS 475
+T + +S ++ GL + + +RAP + L +S H+S
Sbjct: 205 AATSTYRAFAYERQASSSSSRAGGLDWPEATEVSPSRTIRAPAVRTLQRFQSS----HRS 260
Query: 476 TSSSSVSPSFPEEPVLEAVSTR 497
P EPV A S R
Sbjct: 261 RGVGGAVPGAVLEPVARAPSVR 282
>gi|187936935 GRAM domain containing 1C [Homo sapiens]
Length = 662
Score = 36.6 bits (83), Expect = 0.089
Identities = 26/82 (31%), Positives = 43/82 (52%), Gaps = 3/82 (3%)
Query: 401 LSMSYSFDLSDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQV-PAQRKKLLRAPTL 459
LS S SF ++ T++ + + GGL + +N T + + P KKL R P+
Sbjct: 236 LSKSISFTSESISRVSETESF-DGNSSKGGLGKEESQNEKQTKKSLLPTLEKKLTRVPS- 293
Query: 460 AELDSSESEEETLHKSTSSSSV 481
LD +++E +L KS++S SV
Sbjct: 294 KSLDLNKNEYLSLDKSSTSDSV 315
>gi|227496489 multiple C2 domains, transmembrane 2 isoform 2 [Homo
sapiens]
Length = 823
Score = 36.2 bits (82), Expect = 0.12
Identities = 37/143 (25%), Positives = 59/143 (41%), Gaps = 28/143 (19%)
Query: 346 RSRPPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSY 405
R+RP L +S +K+K P +P L R +R+L P+ + LA P Y
Sbjct: 15 RTRPLLINLSKKKVKKNPSKPPDLRAR----HHLDRRLSLSVPDLLEAEALA--PEGRPY 68
Query: 406 SFDLSDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSS 465
S P+S+ V SS+ G+ ++ + L S++ ELD S
Sbjct: 69 S-------GPQSSYTSVPSSLSTAGIFPKSSSSSLKQSEE---------------ELDWS 106
Query: 466 ESEEETLHKSTSSSSVSPSFPEE 488
+ E LH + S + + P E
Sbjct: 107 QEEASHLHVVETDSEEAYASPAE 129
>gi|227496440 multiple C2 domains, transmembrane 2 isoform 1 [Homo
sapiens]
Length = 878
Score = 36.2 bits (82), Expect = 0.12
Identities = 37/143 (25%), Positives = 59/143 (41%), Gaps = 28/143 (19%)
Query: 346 RSRPPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSY 405
R+RP L +S +K+K P +P L R +R+L P+ + LA P Y
Sbjct: 15 RTRPLLINLSKKKVKKNPSKPPDLRAR----HHLDRRLSLSVPDLLEAEALA--PEGRPY 68
Query: 406 SFDLSDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSS 465
S P+S+ V SS+ G+ ++ + L S++ ELD S
Sbjct: 69 S-------GPQSSYTSVPSSLSTAGIFPKSSSSSLKQSEE---------------ELDWS 106
Query: 466 ESEEETLHKSTSSSSVSPSFPEE 488
+ E LH + S + + P E
Sbjct: 107 QEEASHLHVVETDSEEAYASPAE 129
>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis
critical region 1 [Homo sapiens]
Length = 1400
Score = 36.2 bits (82), Expect = 0.12
Identities = 39/186 (20%), Positives = 67/186 (36%), Gaps = 7/186 (3%)
Query: 353 PVSARKLKPTPPRPRSLHERILEEIKAERKLRPV-SPEEIRRSRLAMRPLSMSYSFDLSD 411
P++ +P P ER E P + E P + + D +
Sbjct: 770 PLANENTTLSPAGPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTP 829
Query: 412 VTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEET 471
+ ++T +L E + NG T E S+S + P + + R P E +S E T
Sbjct: 830 LANEKTTPSLAEPTE-NGKRTPFANEKTTSSSAE-PTEHAE--RTPLANENTTSSPAEPT 885
Query: 472 LHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTN 531
++ +++ + FP EP ST + K P + P R ++ PT
Sbjct: 886 ENRERTANEKTTQFPAEPTENRESTANE--KTTPFPAEPTENREWTANENTTLSPAEPTE 943
Query: 532 VRQFLP 537
+ P
Sbjct: 944 HEEMTP 949
>gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]
Length = 2964
Score = 36.2 bits (82), Expect = 0.12
Identities = 40/149 (26%), Positives = 64/149 (42%), Gaps = 16/149 (10%)
Query: 359 LKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTPEST 418
+K P RPR + + ++A + + V+PE R A + LS T +
Sbjct: 1846 VKRRPGRPRKCPLQAVVSMQAFQAAQFVNPELNRDEEGA--------ALHLSPDTVTDVI 1897
Query: 419 KNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHK--ST 476
+ +V+S +N K G +Q RKK P E ++++S E + S
Sbjct: 1898 EAVVQSVNLNPEHKKGLKRKGWLLEEQT---RKKQKPLPEEEEQENNKSFNEAPVEIPSP 1954
Query: 477 SSSSVSPSFPE---EPVLEAVSTRKKPPK 502
S + PS PE +PVL + KKPP+
Sbjct: 1955 SETPAKPSEPESTLQPVLSLIPREKKPPR 1983
>gi|114431248 hypothetical protein LOC205717 [Homo sapiens]
Length = 2245
Score = 35.8 bits (81), Expect = 0.15
Identities = 28/86 (32%), Positives = 42/86 (48%), Gaps = 7/86 (8%)
Query: 410 SDVTTPESTKNLVESSMVNGGLTS------QTKENGLSTSQQVPAQRKKLLRAPTLAELD 463
++V + T NLV ++G S QT L+T+Q VP + A ++ EL
Sbjct: 181 ANVVPVQRTCNLVTPVSISGVYPSENKPWHQTTVPALATNQPVPLCLPAAISAQSILELP 240
Query: 464 SSESEEETLHKSTSSSSVSPSFPEEP 489
+SESE L +TS S ++ S EP
Sbjct: 241 TSESESNVL-GATSGSLIAVSIESEP 265
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 35.8 bits (81), Expect = 0.15
Identities = 42/200 (21%), Positives = 79/200 (39%), Gaps = 34/200 (17%)
Query: 360 KPTPPRPRSLHERILEEIKA------ERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVT 413
K PP P+ + + ++E+I+ E K++ E+ + + +P ++ +V
Sbjct: 9172 KKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVK 9231
Query: 414 TPE-STKNLV--ESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEE 470
P TK +V E M S T+E S VP +K+++ + E
Sbjct: 9232 VPAVHTKKMVISEEKMF---FASHTEEE---VSVTVPEVQKEIV---------TEEKIHV 9276
Query: 471 TLHKSTSSSSVSPSFPEEPVLEAVSTRKKP-------PKFLPISSTPQPERRQP---PQR 520
+ K P PE+P E V+ P PK + P PE ++P P++
Sbjct: 9277 AISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKK 9336
Query: 521 RHSIEKETPTNVRQFLPPSR 540
+ + P ++ +P +
Sbjct: 9337 EPAAPPKVPEVPKKPVPEEK 9356
>gi|38373677 guanine nucleotide-releasing factor 2 isoform b [Homo
sapiens]
Length = 1095
Score = 35.8 bits (81), Expect = 0.15
Identities = 26/86 (30%), Positives = 40/86 (46%), Gaps = 4/86 (4%)
Query: 460 AELDSSESEEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQ 519
AEL ++ E E L+K+T S + P+ E + P + ++P P PP+
Sbjct: 250 AELPLTDREVEILNKTTGMSQSTELLPDATDEEVAPPKPPLPGIRVVDNSPPP--ALPPK 307
Query: 520 RRHSIEKETPTNVRQFLPPSRQSSRS 545
+R S +PT V P SR +S S
Sbjct: 308 KRQS--APSPTRVAVVAPMSRATSGS 331
>gi|38373675 guanine nucleotide-releasing factor 2 isoform a [Homo
sapiens]
Length = 1077
Score = 35.8 bits (81), Expect = 0.15
Identities = 26/86 (30%), Positives = 40/86 (46%), Gaps = 4/86 (4%)
Query: 460 AELDSSESEEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQ 519
AEL ++ E E L+K+T S + P+ E + P + ++P P PP+
Sbjct: 232 AELPLTDREVEILNKTTGMSQSTELLPDATDEEVAPPKPPLPGIRVVDNSPPP--ALPPK 289
Query: 520 RRHSIEKETPTNVRQFLPPSRQSSRS 545
+R S +PT V P SR +S S
Sbjct: 290 KRQS--APSPTRVAVVAPMSRATSGS 313
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.130 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,177,563
Number of Sequences: 37866
Number of extensions: 1597522
Number of successful extensions: 10171
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 238
Number of HSP's that attempted gapping in prelim test: 9586
Number of HSP's gapped (non-prelim): 773
length of query: 756
length of database: 18,247,518
effective HSP length: 110
effective length of query: 646
effective length of database: 14,082,258
effective search space: 9097138668
effective search space used: 9097138668
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.