Search of human proteins with 190684655

Search of human proteins with 190684655

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|190684655 glucose transporter protein 10 isoform a [Homo
sapiens]
         (503 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|190684655 glucose transporter protein 10 isoform a [Homo sapi...   998   0.0  
gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens]   971   0.0  
gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens]   971   0.0  
gi|47933389 solute carrier family 2, member 9 protein isoform 2 ...   390   e-108
gi|47933387 solute carrier family 2, member 9 protein isoform 1 ...   389   e-108
gi|4507013 solute carrier family 2 (facilitated glucose/fructose...   389   e-108
gi|134053883 intestinal facilitative glucose transporter 7 [Homo...   374   e-103
gi|166795299 solute carrier family 2 (facilitated glucose transp...   320   2e-87
gi|4507011 glucose transporter 4 [Homo sapiens]                       315   5e-86
gi|5902090 solute carrier family 2 (facilitated glucose transpor...   292   6e-79
gi|23592238 glucose transporter 14 [Homo sapiens]                     286   2e-77
gi|4557851 solute carrier family 2 (facilitated glucose transpor...   253   2e-67
gi|207447703 solute carrier family 2 (facilitated glucose/fructo...   179   7e-45
gi|21361449 solute carrier family 2 (facilitated glucose transpo...   126   4e-29
gi|223029432 solute carrier family 2 (facilitated glucose transp...   123   4e-28
gi|223029430 solute carrier family 2 (facilitated glucose transp...   117   3e-26
gi|203098995 solute carrier family 2 (facilitated glucose transp...    93   5e-19
gi|21553331 solute carrier family 2 (facilitated glucose transpo...    87   4e-17
gi|13540547 solute carrier family 2 member 10 [Homo sapiens]           84   2e-16
gi|4506999 solute carrier family 22 member 1 isoform a [Homo sap...    61   2e-09
gi|170650643 solute carrier family 22, member 23 isoform a [Homo...    56   7e-08
gi|213021148 SVOP-like isoform 1 [Homo sapiens]                        55   1e-07
gi|166064021 solute carrier family 22 (organic anion transporter...    54   3e-07
gi|4507001 solute carrier family 22 member 2 [Homo sapiens]            54   3e-07
gi|4507005 solute carrier family 22 member 5 [Homo sapiens]            53   7e-07
gi|7662270 synaptic vesicle protein 2B homolog [Homo sapiens]          53   7e-07
gi|216548223 synaptic vesicle glycoprotein 2 [Homo sapiens]            52   1e-06
gi|90669191 solute carrier family 22 member 7 isoform b [Homo sa...    52   2e-06
gi|24497497 solute carrier family 22 member 7 isoform a [Homo sa...    52   2e-06
gi|73695465 synaptic vesicle glycoprotein 2C [Homo sapiens]            49   1e-05

>gi|190684655 glucose transporter protein 10 isoform a [Homo
           sapiens]
          Length = 503

 Score =  998 bits (2581), Expect = 0.0
 Identities = 503/503 (100%), Positives = 503/503 (100%)

Query: 1   MEDELEPSLRPRTQIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQAR 60
           MEDELEPSLRPRTQIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQAR
Sbjct: 1   MEDELEPSLRPRTQIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQAR 60

Query: 61  TGEPLPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFG 120
           TGEPLPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFG
Sbjct: 61  TGEPLPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFG 120

Query: 121 FSRKAGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMG 180
           FSRKAGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMG
Sbjct: 121 FSRKAGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMG 180

Query: 181 QVVGLRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRL 240
           QVVGLRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRL
Sbjct: 181 QVVGLRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRL 240

Query: 241 RGSGDLAGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVY 300
           RGSGDLAGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVY
Sbjct: 241 RGSGDLAGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVY 300

Query: 301 AYASSVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGS 360
           AYASSVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGS
Sbjct: 301 AYASSVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGS 360

Query: 361 IFTVALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGA 420
           IFTVALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGA
Sbjct: 361 IFTVALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGA 420

Query: 421 LMWIMLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHR 480
           LMWIMLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHR
Sbjct: 421 LMWIMLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHR 480

Query: 481 LNFPRRAQGPTWRSLEVIQSTEL 503
           LNFPRRAQGPTWRSLEVIQSTEL
Sbjct: 481 LNFPRRAQGPTWRSLEVIQSTEL 503


>gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens]
          Length = 496

 Score =  971 bits (2511), Expect = 0.0
 Identities = 490/492 (99%), Positives = 490/492 (99%)

Query: 12  RTQIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVL 71
           R  IQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVL
Sbjct: 5   RRLIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVL 64

Query: 72  LMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMI 131
           LMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMI
Sbjct: 65  LMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMI 124

Query: 132 MLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGG 191
           MLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGG
Sbjct: 125 MLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGG 184

Query: 192 PQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELE 251
           PQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELE
Sbjct: 185 PQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELE 244

Query: 252 ELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAG 311
           ELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAG
Sbjct: 245 ELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAG 304

Query: 312 VPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSS 371
           VPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSS
Sbjct: 305 VPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSS 364

Query: 372 FPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGL 431
           FPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGL
Sbjct: 365 FPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGL 424

Query: 432 GFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFPRRAQGPT 491
           GFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFPRRAQGPT
Sbjct: 425 GFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFPRRAQGPT 484

Query: 492 WRSLEVIQSTEL 503
           WRSLEVIQSTEL
Sbjct: 485 WRSLEVIQSTEL 496


>gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens]
          Length = 499

 Score =  971 bits (2511), Expect = 0.0
 Identities = 493/499 (98%), Positives = 493/499 (98%), Gaps = 1/499 (0%)

Query: 5   LEPSLRPRTQIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEP 64
           L   LR R  IQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEP
Sbjct: 2   LHALLRSR-MIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEP 60

Query: 65  LPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRK 124
           LPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRK
Sbjct: 61  LPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRK 120

Query: 125 AGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVG 184
           AGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVG
Sbjct: 121 AGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVG 180

Query: 185 LRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG 244
           LRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG
Sbjct: 181 LRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG 240

Query: 245 DLAGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYAS 304
           DLAGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYAS
Sbjct: 241 DLAGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYAS 300

Query: 305 SVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTV 364
           SVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTV
Sbjct: 301 SVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTV 360

Query: 365 ALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWI 424
           ALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWI
Sbjct: 361 ALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWI 420

Query: 425 MLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFP 484
           MLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFP
Sbjct: 421 MLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFP 480

Query: 485 RRAQGPTWRSLEVIQSTEL 503
           RRAQGPTWRSLEVIQSTEL
Sbjct: 481 RRAQGPTWRSLEVIQSTEL 499


>gi|47933389 solute carrier family 2, member 9 protein isoform 2
           [Homo sapiens]
          Length = 511

 Score =  390 bits (1001), Expect = e-108
 Identities = 198/481 (41%), Positives = 297/481 (61%), Gaps = 1/481 (0%)

Query: 2   EDELEPSLRPRTQIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQART 61
           EDE   S + +      +L+ ++  A  G +F +GYNLS++NAPT +I+ F NE+W+ R 
Sbjct: 10  EDEESDSAKKKLDWSCSLLVASLAGA-FGSSFLYGYNLSVVNAPTPYIKAFYNESWERRH 68

Query: 62  GEPLPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGF 121
           G P+    + L+WS+ VS++ +GGL G L+   +   LGRK +LL NN F +SAA+L   
Sbjct: 69  GRPIDPDTLTLLWSVTVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMAC 128

Query: 122 SRKAGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQ 181
           S +AG+FEM+++GR ++G++ GV++++ PMYL E +PKE+RG++   +AIF  +G+  GQ
Sbjct: 129 SLQAGAFEMLIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQ 188

Query: 182 VVGLRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLR 241
           ++GL ELLG    WP L    +VP  +QL SLP LP+SPRYLL++  +    + A +   
Sbjct: 189 LLGLPELLGKESTWPYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFL 248

Query: 242 GSGDLAGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYA 301
           G  D++ E+EE+  E    +  R     EL +   +R QV +++V  +  +LCG ++++ 
Sbjct: 249 GKADVSQEVEEVLAESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWF 308

Query: 302 YASSVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSI 361
           Y +S+F KAG+P AKI Y  + TG  E L AV S +VIE +GRR LLIGG+ LM  +   
Sbjct: 309 YTNSIFGKAGIPPAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGT 368

Query: 362 FTVALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGAL 421
            T+ L LQ   PW  YL++  I A I SF  GP G+  IL  E F Q  RPAA ++ G +
Sbjct: 369 LTITLTLQDHAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTV 428

Query: 422 MWIMLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRL 481
            W+    VGL FPFI ++L  + ++ F  +C+ GAIY    LPETK +T+ EIS+   + 
Sbjct: 429 NWLSNFAVGLLFPFIQKSLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKR 488

Query: 482 N 482
           N
Sbjct: 489 N 489


>gi|47933387 solute carrier family 2, member 9 protein isoform 1
           [Homo sapiens]
          Length = 540

 Score =  389 bits (1000), Expect = e-108
 Identities = 195/463 (42%), Positives = 289/463 (62%)

Query: 20  LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVS 79
           LL+   A   G +F +GYNLS++NAPT +I+ F NE+W+ R G P+    + L+WS+ VS
Sbjct: 56  LLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVS 115

Query: 80  LYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG 139
           ++ +GGL G L+   +   LGRK +LL NN F +SAA+L   S +AG+FEM+++GR ++G
Sbjct: 116 IFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMG 175

Query: 140 VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLL 199
           ++ GV++++ PMYL E +PKE+RG++   +AIF  +G+  GQ++GL ELLG    WP L 
Sbjct: 176 IDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLF 235

Query: 200 ASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAA 259
              +VP  +QL SLP LP+SPRYLL++  +    + A +   G  D++ E+EE+  E   
Sbjct: 236 GVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRV 295

Query: 260 CQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQY 319
            +  R     EL +   +R QV +++V  +  +LCG ++++ Y +S+F KAG+P AKI Y
Sbjct: 296 QRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPY 355

Query: 320 AIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYLA 379
             + TG  E L AV S +VIE +GRR LLIGG+ LM  +    T+ L LQ   PW  YL+
Sbjct: 356 VTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLS 415

Query: 380 MACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEA 439
           +  I A I SF  GP G+  IL  E F Q  RPAA ++ G + W+    VGL FPFI ++
Sbjct: 416 IVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKS 475

Query: 440 LSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLN 482
           L  + ++ F  +C+ GAIY    LPETK +T+ EIS+   + N
Sbjct: 476 LDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRN 518


>gi|4507013 solute carrier family 2 (facilitated glucose/fructose
           transporter), member 5 isoform 1 [Homo sapiens]
          Length = 501

 Score =  389 bits (998), Expect = e-108
 Identities = 199/464 (42%), Positives = 290/464 (62%)

Query: 19  ILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIV 78
           +L L    A  G +FQ+GYN++ +N+P L +Q+F NET+  RTGE + D  + L+WS+ V
Sbjct: 16  VLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLLWSVTV 75

Query: 79  SLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLV 138
           S++P GG  G+LL GPL    GRK +LL NNIF +  AIL G SR A SFE+I++ RLLV
Sbjct: 76  SMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLV 135

Query: 139 GVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLL 198
           G+ AGVS N+ PMYLGE APK LRGA+ +   +F  +GI++ Q+ GLR LL     WP+L
Sbjct: 136 GICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPIL 195

Query: 199 LASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERA 258
           L    VP ALQL  LP  PESPRYLLI   D  A   AL+ LRG   +  E+ E+ +E  
Sbjct: 196 LGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVAEIRQEDE 255

Query: 259 ACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQ 318
           A +        +LF+ R+LR Q+ S++VL    +L G +++Y YA  ++  AGVPE  +Q
Sbjct: 256 AEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGVPEEHVQ 315

Query: 319 YAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYL 378
           Y   GTG+  ++    +  V+E +GRR+LL+ G+S+      + T AL LQ +  W  Y+
Sbjct: 316 YVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTAALALQDTVSWMPYI 375

Query: 379 AMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIME 438
           ++ C+ ++++   +GP+ +  +L TE+F Q +RP+A MV G++ W+    VGL FPFI E
Sbjct: 376 SIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPFIQE 435

Query: 439 ALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLN 482
            L  + ++ F  +C+   IY  L +PETK KTF EI++   ++N
Sbjct: 436 GLGPYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIFTKMN 479


>gi|134053883 intestinal facilitative glucose transporter 7 [Homo
           sapiens]
          Length = 512

 Score =  374 bits (960), Expect = e-103
 Identities = 201/485 (41%), Positives = 292/485 (60%), Gaps = 3/485 (0%)

Query: 1   MEDELEPSLRPRTQIQGRI---LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETW 57
           ME++   +  P    +GR+   LLL   +A  G  FQ+GYNLS++N P    + F NET+
Sbjct: 1   MENKEAGTPPPIPSREGRLQPTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETY 60

Query: 58  QARTGEPLPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAI 117
             R    +   L+LL+WS  VS++PLGGL G+LL G L  + GRK +LL+NNIF +  AI
Sbjct: 61  FERHATFMDGKLMLLLWSCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAI 120

Query: 118 LFGFSRKAGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGI 177
           L G S+ A +FE+I+  R+++GV AG+S +  PMYLGE APK LRG V   + +F  +G+
Sbjct: 121 LMGVSKVAKAFELIVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGV 180

Query: 178 VMGQVVGLRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAAL 237
            + Q+  L+ +LG P  WP+LLA   VP  LQL +LP  PESPRY LI  GD      AL
Sbjct: 181 FLAQIFSLQAILGNPAGWPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQAL 240

Query: 238 RRLRGSGDLAGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGND 297
           RRLRG  D+  ELE++  E  A +         L   R+LR Q+ S++VL +  +L G +
Sbjct: 241 RRLRGHTDMEAELEDMRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGIN 300

Query: 298 SVYAYASSVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTC 357
           ++  YA +++  AGV  A  QY  +G+G   ++  + S V++ER+GRR LL+ GY +   
Sbjct: 301 AINYYADTIYTSAGVEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGS 360

Query: 358 WGSIFTVALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMV 417
              + TV L  Q+  P   YL + C+FA+I    IGP+ V  ++ TE+F Q +R AA MV
Sbjct: 361 ACLVLTVVLLFQNRVPELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMV 420

Query: 418 CGALMWIMLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKE 477
            GA+ W+   ++G  FP I EA+  + ++ F G+C+  AIY  + +PETKGKTF EI++ 
Sbjct: 421 DGAVHWLTNFIIGFLFPSIQEAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRI 480

Query: 478 LHRLN 482
             + N
Sbjct: 481 FAKRN 485


>gi|166795299 solute carrier family 2 (facilitated glucose
           transporter), member 1 [Homo sapiens]
          Length = 492

 Score =  320 bits (819), Expect = 2e-87
 Identities = 174/471 (36%), Positives = 267/471 (56%), Gaps = 7/471 (1%)

Query: 5   LEPSLRPRTQIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEP 64
           +EPS +  T   GR++L       + G+ QFGYN  +INAP   I+EF N+TW  R GE 
Sbjct: 1   MEPSSKKLT---GRLMLAV--GGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGES 55

Query: 65  LPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRK 124
           +    +  +WSL V+++ +GG+ G+   G      GR+ S+L+ N+    +A+L GFS+ 
Sbjct: 56  ILPTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKL 115

Query: 125 AGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVG 184
             SFEM++LGR ++GV  G++    PMY+GE +P  LRGA+     +   +GI++ QV G
Sbjct: 116 GKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFG 175

Query: 185 LRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG 244
           L  ++G    WPLLL+   +P  LQ   LP  PESPR+LLI+  +     + L++LRG+ 
Sbjct: 176 LDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTA 235

Query: 245 DLAGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYAS 304
           D+  +L+E++EE       +     ELF+  A R+ +   VVL  + +L G ++V+ Y++
Sbjct: 236 DVTHDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYST 295

Query: 305 SVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTV 364
           S+F KAGV +    YA IG+G       VVS  V+ER GRR L + G + M     + T+
Sbjct: 296 SIFEKAGVQQP--VYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTI 353

Query: 365 ALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWI 424
           AL L    PW  YL++  IF F+  F +GP  +   +  ELF Q  RPAA  V G   W 
Sbjct: 354 ALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWT 413

Query: 425 MLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEIS 475
              +VG+ F ++ +    ++++ F  + V   I+T   +PETKG+TF EI+
Sbjct: 414 SNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIA 464


>gi|4507011 glucose transporter 4 [Homo sapiens]
          Length = 509

 Score =  315 bits (808), Expect = 5e-86
 Identities = 181/497 (36%), Positives = 279/497 (56%), Gaps = 16/497 (3%)

Query: 11  PRTQIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTG----EPLP 66
           P+ ++ G ++L    A  + G+ QFGYN+ +INAP   I++  NETW  R G      +P
Sbjct: 16  PQQRVTGTLVLAVFSA--VLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIP 73

Query: 67  DHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAG 126
              +  +W+L V+++ +GG+  + L G ++  LGRK+++LVNN+  V    L G +  A 
Sbjct: 74  PGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAA 133

Query: 127 SFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLR 186
           S+EM++LGR L+G  +G++  + PMY+GE AP  LRGA+   + +   +GI++ QV+GL 
Sbjct: 134 SYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLE 193

Query: 187 ELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDL 246
            LLG    WPLLL   ++P  LQL  LP  PESPRYL I          +L+RL G  D+
Sbjct: 194 SLLGTASLWPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADV 253

Query: 247 AGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSV 306
           +G L EL++E+   +  R     +L   R  R+ +   VVL  + +L G ++V+ Y++S+
Sbjct: 254 SGVLAELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSI 313

Query: 307 FRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVAL 366
           F  AGV +    YA IG G    +  +VS +++ER GRR L + G + M     + TVAL
Sbjct: 314 FETAGVGQP--AYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVAL 371

Query: 367 CLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIML 426
            L    P   Y+++  IF F+  F IGP  +   +  ELF Q  RPAA  V G   W   
Sbjct: 372 LLLERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSN 431

Query: 427 ILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFPRR 486
            ++G+GF ++ EA+  ++++ F  + +   I+T L +PET+G+TF +IS   HR      
Sbjct: 432 FIIGMGFQYVAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAFHRT----- 486

Query: 487 AQGPTWRSLEVIQSTEL 503
              P+    EV  STEL
Sbjct: 487 ---PSLLEQEVKPSTEL 500


>gi|5902090 solute carrier family 2 (facilitated glucose
           transporter), member 3 [Homo sapiens]
          Length = 496

 Score =  292 bits (747), Expect = 6e-79
 Identities = 161/457 (35%), Positives = 258/457 (56%), Gaps = 3/457 (0%)

Query: 20  LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVS 79
           L+  I  A IG +FQFGYN  +INAP   I+EF N+T   +   P  + L+  +WSL V+
Sbjct: 10  LIFAITVATIG-SFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWSLSVA 68

Query: 80  LYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG 139
           ++ +GG+ G+   G      GR+ S+L+ N+  V+     G  + A S EM++LGRL++G
Sbjct: 69  IFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIG 128

Query: 140 VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLL 199
           +  G+     PMY+GE +P  LRGA    + +   +GI++ Q+ GL  +LG  + WPLLL
Sbjct: 129 LFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLL 188

Query: 200 ASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAA 259
              ++P  LQ A+LP  PESPR+LLI+  + E     L+RL G+ D++ +++E+++E A 
Sbjct: 189 GFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESAR 248

Query: 260 CQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQY 319
               +     ELF+  + R+ +   +VL  + +L G ++V+ Y++ +F+ AGV E    Y
Sbjct: 249 MSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEP--IY 306

Query: 320 AIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYLA 379
           A IG G    +  VVS  ++ER GRR L + G   M    ++ TV+L L+ ++    ++ 
Sbjct: 307 ATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGMSFVC 366

Query: 380 MACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEA 439
           +  I  F+  F IGP  +   +  ELF Q  RPAA  V G   W    LVGL FP     
Sbjct: 367 IGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHY 426

Query: 440 LSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISK 476
           L  ++++ F G  +    +T   +PET+G+TF++I++
Sbjct: 427 LGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITR 463


>gi|23592238 glucose transporter 14 [Homo sapiens]
          Length = 520

 Score =  286 bits (733), Expect = 2e-77
 Identities = 159/472 (33%), Positives = 261/472 (55%), Gaps = 3/472 (0%)

Query: 5   LEPSLRPRTQIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEP 64
           L   ++P T      L+  I  A IG +FQFGYN  +INAP   I+EF N+T   +   P
Sbjct: 19  LTSRMKPHTLAVTPALIFAITVATIG-SFQFGYNTGVINAPETIIKEFINKTLTDKANAP 77

Query: 65  LPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRK 124
             + L+  +WSL V+++ +GG+ G+   G      GR+ S+L+ N+   +   L G  + 
Sbjct: 78  PSEVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKI 137

Query: 125 AGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVG 184
           A S EM++LGRL++G+  G+     PMY+GE +P  LRGA    + +   +GI++ Q+ G
Sbjct: 138 AESVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFG 197

Query: 185 LRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG 244
           L  +LG  + WP+LL   ++P  LQ A+LP  PESPR+LLI+    E     L+RL G+ 
Sbjct: 198 LELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQ 257

Query: 245 DLAGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYAS 304
           D++ +++E+++E A     +     ELF+  + R+ +   +VL  + +L G ++V+ Y++
Sbjct: 258 DVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYST 317

Query: 305 SVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTV 364
            +F+ AGV +    YA I  G    +  ++S  ++ER GRR L + G   M    ++ TV
Sbjct: 318 GIFKDAGVQQP--IYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTV 375

Query: 365 ALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWI 424
           +L L++ +    ++ +  I  F+  F IGP  +   +  ELF Q  RPAA  V G   W 
Sbjct: 376 SLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWT 435

Query: 425 MLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISK 476
              LVGL FP     L  ++++ F G  +    +T   +PET+G+TF++I++
Sbjct: 436 SNFLVGLLFPSAAYYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITR 487


>gi|4557851 solute carrier family 2 (facilitated glucose
           transporter), member 2 [Homo sapiens]
          Length = 524

 Score =  253 bits (647), Expect = 2e-67
 Identities = 157/499 (31%), Positives = 249/499 (49%), Gaps = 45/499 (9%)

Query: 20  LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDH----------- 68
           L+ T+  A +G +FQFGY++ +INAP    Q+     ++   G PL D            
Sbjct: 10  LVFTVITAVLG-SFQFGYDIGVINAP----QQVIISHYRHVLGVPLDDRKAINNYVINST 64

Query: 69  ---------------------------LVLLMWSLIVSLYPLGGLFGALLAGPLAITLGR 101
                                      L+ ++WSL VS + +GG+  +   G L  TLGR
Sbjct: 65  DELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDTLGR 124

Query: 102 KKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKEL 161
            K++LV NI  +  A+L GFS+   S  +I+ GR + G+  G+   + PMY+GE AP  L
Sbjct: 125 IKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTAL 184

Query: 162 RGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPR 221
           RGA+     +    GI++ Q++GL  +LG    W +LL    V   LQ   L   PESPR
Sbjct: 185 RGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESPR 244

Query: 222 YLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAACQGCRARRPWELFQHRALRRQV 281
           YL I   +      +L+RLRG  D+  ++ E+ +ER      +     +LF + + R+ +
Sbjct: 245 YLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQPI 304

Query: 282 TSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIER 341
              ++L  A +  G + ++ Y++S+F+ AG+  +K  YA IG G+  ++   VS  ++E+
Sbjct: 305 LVALMLHVAQQFSGINGIFYYSTSIFQTAGI--SKPVYATIGVGAVNMVFTAVSVFLVEK 362

Query: 342 VGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGIL 401
            GRR L + G S M       +V L L + F W  Y++M  IF F+  F IGP  +   +
Sbjct: 363 AGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFM 422

Query: 402 ATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGL 461
             E F Q  RPAA  +     W    +V L F +I +    +++  F GV +   ++T  
Sbjct: 423 VAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTFF 482

Query: 462 FLPETKGKTFQEISKELHR 480
            +PETKGK+F+EI+ E  +
Sbjct: 483 KVPETKGKSFEEIAAEFQK 501


>gi|207447703 solute carrier family 2 (facilitated glucose/fructose
           transporter), member 5 isoform 2 [Homo sapiens]
          Length = 244

 Score =  179 bits (453), Expect = 7e-45
 Identities = 88/171 (51%), Positives = 119/171 (69%)

Query: 19  ILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIV 78
           +L L    A  G +FQ+GYN++ +N+P L +Q+F NET+  RTGE + D  + L+WS+ V
Sbjct: 16  VLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLLWSVTV 75

Query: 79  SLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLV 138
           S++P GG  G+LL GPL    GRK +LL NNIF +  AIL G SR A SFE+I++ RLLV
Sbjct: 76  SMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLV 135

Query: 139 GVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELL 189
           G+ AGVS N+ PMYLGE APK LRGA+ +   +F  +GI++ Q+ GLR LL
Sbjct: 136 GICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLL 186


>gi|21361449 solute carrier family 2 (facilitated glucose
           transporter), member 8 [Homo sapiens]
          Length = 477

 Score =  126 bits (317), Expect = 4e-29
 Identities = 133/506 (26%), Positives = 220/506 (43%), Gaps = 74/506 (14%)

Query: 3   DELEPSLRPR--TQIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQAR 60
           +E +P L P   +  +GR + L   AA +G    FG+ L   +     +Q         R
Sbjct: 7   EETQPLLGPPGGSAPRGRRVFLAAFAAALG-PLSFGFALGYSSPAIPSLQ---------R 56

Query: 61  TGEPLP--DHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNI-FVVSAAI 117
              P P  D      +  +V+L   G   G +L G L    GRK SLL+ ++ FV   A+
Sbjct: 57  AAPPAPRLDDAAASWFGAVVTL---GAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAV 113

Query: 118 LFGFSRKAGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGI 177
           +      A    M++ GRLL G+  GV+  + P+Y+ E A   +RG +     +   +GI
Sbjct: 114 ITA----AQDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGI 169

Query: 178 VMGQVVGLRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAAL 237
           +      L  L G    W  L     VP +L L  +  +PE+PR+LL      EA +AAL
Sbjct: 170 L------LAYLAGWVLEWRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEA-MAAL 222

Query: 238 RRLRGSGDLAGELEELEEERAACQGCRARRPWELFQHRALRRQ--VTSLVVLGSAM---- 291
           R L GS +   E   +  E++               H AL RQ  +    ++G ++    
Sbjct: 223 RFLWGS-EQGWEDPPIGAEQSF--------------HLALLRQPGIYKPFIIGVSLMAFQ 267

Query: 292 ELCGNDSVYAYASSVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGG 351
           +L G ++V  YA ++F +A   ++ +   ++G    ++L   V+ ++++R GRR+LL+  
Sbjct: 268 QLSGVNAVMFYAETIFEEAKFKDSSLASVVVGV--IQVLFTAVAALIMDRAGRRLLLVLS 325

Query: 352 YSLMTCWGSIFTVALCLQSSFPWT---------------------LYLAMACIFAFILSF 390
             +M    S F     L    P                        +LA+  +  FI  F
Sbjct: 326 GVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVSAQPVDASVGLAWLAVGSMCLFIAGF 385

Query: 391 GIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEALSHF-LYVPFL 449
            +G   +  +L +E+F    +  A  +C    W+M  LV   F  +ME L  +  +    
Sbjct: 386 AVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLAS 445

Query: 450 GVCVCGAIYTGLFLPETKGKTFQEIS 475
             C+   ++T   +PETKGKT ++I+
Sbjct: 446 AFCIFSVLFTLFCVPETKGKTLEQIT 471


>gi|223029432 solute carrier family 2 (facilitated glucose
           transporter), member 6 isoform 1 [Homo sapiens]
          Length = 507

 Score =  123 bits (308), Expect = 4e-28
 Identities = 128/492 (26%), Positives = 215/492 (43%), Gaps = 69/492 (14%)

Query: 18  RILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPD-HLVLLMWSL 76
           R+ L T  A  + G F FGY L +  +P +   E + +          PD HL     S 
Sbjct: 37  RVFLATFAA--VLGNFSFGYAL-VYTSPVIPALERSLD----------PDLHLTKSQASW 83

Query: 77  IVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFE--MIMLG 134
             S++ LG   G L A  L   LGRK S++ +   V SAA   G++  AG+    M++LG
Sbjct: 84  FGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSA--VPSAA---GYALMAGAHGLWMLLLG 138

Query: 135 RLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQA 194
           R L G   G++    P+Y+ E AP  +RGA+  +  +    G +    +GL  LL     
Sbjct: 139 RTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL--LL----P 192

Query: 195 WPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG-DLAGELEEL 253
           W  L  +   P  + +  L  +P SPR+LL    D EA L AL  LRG+  D+  E E++
Sbjct: 193 WRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEA-LRALAWLRGTDVDVHWEFEQI 251

Query: 254 EEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVP 313
           ++     +   +R  W   +   + R +T  +++    +L G   +  Y  S+F    V 
Sbjct: 252 QDN---VRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVL 308

Query: 314 EAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLM------------------ 355
                 A I  G+  LL+ +++ + ++  GR+VLL    ++M                  
Sbjct: 309 LPPKDDAAI-VGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRPL 367

Query: 356 ----------TCWGSIFTVALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATEL 405
                       WG +   A  L +   +   + +     FI+ + +G   +T +L +E+
Sbjct: 368 SPNSTAGLESESWGDL---AQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEV 424

Query: 406 FDQMARPAACMVCGALMWIMLILVGLGFPFIMEALSHFLYVPFL---GVCVCGAIYTGLF 462
               AR  A  +C    W+   ++   F  ++      L VPF     +C+   ++TG  
Sbjct: 425 LPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFG--LQVPFFFFAAICLVSLVFTGCC 482

Query: 463 LPETKGKTFQEI 474
           +PETKG++ ++I
Sbjct: 483 VPETKGRSLEQI 494


>gi|223029430 solute carrier family 2 (facilitated glucose
           transporter), member 6 isoform 2 [Homo sapiens]
          Length = 445

 Score =  117 bits (292), Expect = 3e-26
 Identities = 122/464 (26%), Positives = 202/464 (43%), Gaps = 75/464 (16%)

Query: 18  RILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPD-HLVLLMWSL 76
           R+ L T  A  + G F FGY L +  +P +   E + +          PD HL     S 
Sbjct: 37  RVFLATFAA--VLGNFSFGYAL-VYTSPVIPALERSLD----------PDLHLTKSQASW 83

Query: 77  IVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFE--MIMLG 134
             S++ LG   G L A  L   LGRK S++ +   V SAA   G++  AG+    M++LG
Sbjct: 84  FGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSA--VPSAA---GYALMAGAHGLWMLLLG 138

Query: 135 RLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQA 194
           R L G   G++    P+Y+ E AP  +RGA+  +  +    G +    +GL  LL     
Sbjct: 139 RTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL--LL----P 192

Query: 195 WPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG-DLAGELEEL 253
           W  L  +   P  + +  L  +P SPR+LL    D EA L AL  LRG+  D+  E E++
Sbjct: 193 WRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEA-LRALAWLRGTDVDVHWEFEQI 251

Query: 254 EEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVP 313
           ++     +   +R  W   +   + R +T  +++    +L G   +  Y  S+F    V 
Sbjct: 252 QDN---VRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVL 308

Query: 314 EAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFP 373
                 A I  G+  LL+ +++ + ++  GR+VLL                         
Sbjct: 309 LPPKDDAAI-VGAVRLLSVLIAALTMDLAGRKVLL------------------------- 342

Query: 374 WTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGF 433
                       F+  + +G   +T +L +E+    AR  A  +C    W+   ++   F
Sbjct: 343 ------------FVSGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSF 390

Query: 434 PFIMEALSHFLYVPFL---GVCVCGAIYTGLFLPETKGKTFQEI 474
             ++      L VPF     +C+   ++TG  +PETKG++ ++I
Sbjct: 391 LPVVSTFG--LQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQI 432


>gi|203098995 solute carrier family 2 (facilitated glucose
           transporter), member 13 [Homo sapiens]
          Length = 648

 Score = 93.2 bits (230), Expect = 5e-19
 Identities = 80/325 (24%), Positives = 140/325 (43%), Gaps = 24/325 (7%)

Query: 31  GTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVSLYPLGGLFGAL 90
           G F FGY+  +++   L ++   +              L  L   L+VS         AL
Sbjct: 91  GGFLFGYDTGVVSGAMLLLKRQLS--------------LDALWQELLVSSTVGAAAVSAL 136

Query: 91  LAGPLAITLGRKKS-LLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVGVNAGVSMNIQ 149
             G L    GR+ + LL + +F   +A+L   + K    E ++ GRL+VG+  G++    
Sbjct: 137 AGGALNGVFGRRAAILLASALFTAGSAVLAAANNK----ETLLAGRLVVGLGIGIASMTV 192

Query: 150 PMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLLASCLVPGALQ 209
           P+Y+ E +P  LRG +   + +F   G     VV           W  +L    VP  +Q
Sbjct: 193 PVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQ 252

Query: 210 LASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELE---EERAACQGCRAR 266
                 LPESPR+ LI  G T+     L ++RG+  +  E + ++   EE     G    
Sbjct: 253 FFGFLFLPESPRW-LIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIEEEEKEVGSAGP 311

Query: 267 RPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQYAIIG-TG 325
               +  +   RR +     L    +L G +++  Y++++ + +GV + ++   +   T 
Sbjct: 312 VICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASVTA 371

Query: 326 SCELLTAVVSCVVIERVGRRVLLIG 350
               +  +V   ++E+VGRR L  G
Sbjct: 372 FTNFIFTLVGVWLVEKVGRRKLTFG 396



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 4/104 (3%)

Query: 372 FPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGL 431
           + WT  L +     F    G+GP   T  + +E++   AR         + WI  +LV L
Sbjct: 505 YSWTALLGLILYLVFFAP-GMGPMPWT--VNSEIYPLWARSTGNACSSGINWIFNVLVSL 561

Query: 432 GFPFIMEALSHF-LYVPFLGVCVCGAIYTGLFLPETKGKTFQEI 474
            F    E L+++  +  + G    G ++    LPETKGK  +EI
Sbjct: 562 TFLHTAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEI 605


>gi|21553331 solute carrier family 2 (facilitated glucose
           transporter), member 12 [Homo sapiens]
          Length = 617

 Score = 87.0 bits (214), Expect = 4e-17
 Identities = 75/341 (21%), Positives = 152/341 (44%), Gaps = 25/341 (7%)

Query: 17  GRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSL 76
           G    L+   A + G    GY L II+   L I+     +   +               +
Sbjct: 37  GMFTFLSSVTAAVSGLL-VGYELGIISGALLQIKTLLALSCHEQ--------------EM 81

Query: 77  IVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRL 136
           +VS   +G L  +L  G L    GR+ ++++++  +   +++   S    S+ ++++GR+
Sbjct: 82  VVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSL---SYTVLIVGRI 138

Query: 137 LVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWP 196
            +GV+  +S     +Y+ E AP+  RG +   + +   +GI+   +            W 
Sbjct: 139 AIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNY-AFANVFHGWK 197

Query: 197 LLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEE 256
            +    +  G LQ  ++  LP SPR+L++  G   A    L RLR   D     EEL   
Sbjct: 198 YMFGLVIPLGVLQAIAMYFLPPSPRFLVMK-GQEGAASKVLGRLRALSDTT---EELTVI 253

Query: 257 RAACQGCRARRPWELFQHR-ALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEA 315
           +++ +       W+LF+ +  +R ++   + L   +++ G  ++  YAS+V +  G    
Sbjct: 254 KSSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSN 313

Query: 316 K-IQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLM 355
           +    A  G G  ++++ + + ++++ VG +  L  G S+M
Sbjct: 314 EAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVM 354



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 26/111 (23%), Positives = 60/111 (54%), Gaps = 7/111 (6%)

Query: 377 YLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFI 436
           +L++A +  ++ +F IG   +  ++ +E+F    R  A  +  ++ W + +L+ L F  +
Sbjct: 462 WLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTV 521

Query: 437 MEALSH----FLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNF 483
            + +      F+Y     + +   ++  +F+PETKG + ++IS EL ++N+
Sbjct: 522 TDLIGLPWVCFIYTI---MSLASLLFVVMFIPETKGCSLEQISMELAKVNY 569


>gi|13540547 solute carrier family 2 member 10 [Homo sapiens]
          Length = 541

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 90/339 (26%), Positives = 145/339 (42%), Gaps = 42/339 (12%)

Query: 21  LLTICAA-GIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVS 79
           +L +CA+  + G   FGY L++I+   L +Q              L   L  L    +V 
Sbjct: 7   VLPLCASVSLLGGLTFGYELAVISGALLPLQ--------------LDFGLSCLEQEFLVG 52

Query: 80  LYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG 139
              LG L  +L+ G L    GRK+++L +N+ +++ ++  G    AGS   ++LGR +VG
Sbjct: 53  SLLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGL---AGSLAWLVLGRAVVG 109

Query: 140 VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLL 199
               +S     +Y+ E      RG +         +GI++   +    L G P  W  + 
Sbjct: 110 FAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYA-LAGTPWGWRHMF 168

Query: 200 ASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAA 259
                P  LQ  SL  LP           D  A    L  L+G     GE  +L   R  
Sbjct: 169 GWATAPAVLQSLSLLFLPAGT--------DETATHKDLIPLQG-----GEAPKLGPGRPR 215

Query: 260 CQGCRARRPWELFQHRALRRQVTSLVVLGSAM--ELCGNDSVYAYASSVFRKAGVPE-AK 316
                     +LF+ R   R  T+ V LG  +  +L G  +V  YAS++F   G    + 
Sbjct: 216 YSFL------DLFRARDNMRGRTT-VGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGGSS 268

Query: 317 IQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLM 355
              A +G G+ ++   + +  +++R GRR LL+ G +LM
Sbjct: 269 AVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALM 307



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 32/113 (28%), Positives = 53/113 (46%), Gaps = 8/113 (7%)

Query: 374 WTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGF 433
           WT   A+ C+  F+ +F  G   VT ++ +E++    R  A   C +  W   + + L F
Sbjct: 410 WT---ALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSF 466

Query: 434 PFIMEALS---HFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNF 483
             ++  +     FL      V   G IY  LF+PETKG++  EI ++  +  F
Sbjct: 467 LDLIGTIGLSWTFLLYGLTAVLGLGFIY--LFVPETKGQSLAEIDQQFQKRRF 517


>gi|4506999 solute carrier family 22 member 1 isoform a [Homo
           sapiens]
          Length = 554

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 103/410 (25%), Positives = 167/410 (40%), Gaps = 32/410 (7%)

Query: 76  LIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGR 135
           L  S    G LFG+L  G  A   GRK  LL   +    + +L  FS    ++  ++L R
Sbjct: 150 LFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFS---PNYMSMLLFR 206

Query: 136 LLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAW 195
           LL G+ +  +       + E      R  VA+   +   +G+V   + GL   L     W
Sbjct: 207 LLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLV--ALTGLAYAL---PHW 261

Query: 196 PLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDL-AGELEELE 254
             L  +  +P  L L     +PESPR+LL    +TEA        + +G L   +L+ L 
Sbjct: 262 RWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPADLKMLS 321

Query: 255 EERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPE 314
            E    +        +LF+   LR++   L      M L   DSV      +    G   
Sbjct: 322 LEEDVTEKLSPSFA-DLFRTPRLRKRTFIL------MYLWFTDSV--LYQGLILHMGATS 372

Query: 315 AKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPW 374
             +    + +   E+  A ++ + I+RVG R+  +   +L+   G+   V + +     W
Sbjct: 373 GNLYLDFLYSALVEIPGAFIALITIDRVG-RIYPMAMSNLLA--GAACLVMIFISPDLHW 429

Query: 375 TLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFP 434
            L + + C+    ++  I    +  ++  EL+    R    MVC +L  I     G+  P
Sbjct: 430 -LNIIIMCVGRMGITIAI---QMICLVNAELYPTFVRNLGVMVCSSLCDI----GGIITP 481

Query: 435 FIMEALSH-FLYVPFLGVCVCGAIYTG--LFLPETKGKTFQEISKELHRL 481
           FI+  L   +  +P +   V G +  G  L LPETKG    E  K+   L
Sbjct: 482 FIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENL 531


>gi|170650643 solute carrier family 22, member 23 isoform a [Homo
           sapiens]
          Length = 686

 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 99/431 (22%), Positives = 172/431 (39%), Gaps = 60/431 (13%)

Query: 74  WSLIVSLYPL--GGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMI 131
           W + ++ + L  G +FG L+ G +A  +GR+  LL + IF++   +    S     F  +
Sbjct: 227 WKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTL 286

Query: 132 MLGRLLVG-VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLG 190
              R   G   AG+ + +  + + E  P   R  + M ++     G  +  + GL  L  
Sbjct: 287 ---RFFEGFCLAGIILTLYALRI-ELCPPGKRFMITMVASFVAMAGQFL--MPGLAALC- 339

Query: 191 GPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAAL-----RRLRGSGD 245
             + W +L A  + P  L L    + PES R+L+       A    L      R+   GD
Sbjct: 340 --RDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGD 397

Query: 246 LAGELEELEEERAACQGCRARRPWELFQHRAL-RRQVTSLVVLGSAMELCGNDSVYAYAS 304
           + G + ELE+E        +RRP ++   + +  R +   +V+     L G    + +A 
Sbjct: 398 IKGVIPELEKE-------LSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFAR 450

Query: 305 SVF-RKAGVPEAKIQYA-IIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIF 362
           S+   +  VP  +  YA    T S  L++ +  CVV+  +GRR  L+  + ++T   S+ 
Sbjct: 451 SMMGHEVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLL-LFMILTALASLL 509

Query: 363 TVALC-------------LQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQM 409
            + L              +  S      +A + +  F  S  +G   V      E+   +
Sbjct: 510 QLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMF-ASHAVGSLSV--FFCAEITPTV 566

Query: 410 ARPAACMVCGALMWIMLILVGLGFPFIMEAL-------SHFLYVPFLGVCVCGAIYTGLF 462
            R      CG L    L+L   GF  +   +        +FL+      C    I   L 
Sbjct: 567 IR------CGGL---GLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILL 617

Query: 463 LPETKGKTFQE 473
           LPE++ +   E
Sbjct: 618 LPESRDQNLPE 628


>gi|213021148 SVOP-like isoform 1 [Homo sapiens]
          Length = 492

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 46/167 (27%), Positives = 84/167 (50%), Gaps = 9/167 (5%)

Query: 75  SLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLG 134
           +L+ ++   G +  ++L G LA   GR K LL++ ++    ++L  F   A S+   +  
Sbjct: 87  ALVTTMVFFGYMVFSILFGLLADRYGRWKILLISFLWGAYFSLLTSF---APSYIWFVFL 143

Query: 135 RLLVGVNAGVSMNIQPMYLG-ESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQ 193
           R +VG   GVS + Q + +  E  P + RG +   S +F   G ++  ++GL  ++    
Sbjct: 144 RTMVG--CGVSGHSQGLIIKTEFLPTKYRGYMLPLSQVFWLAGSLL--IIGLASVIIPTI 199

Query: 194 AWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRL 240
            W  L+    +PG + + +   +PES R+  +  G+T A LA L R+
Sbjct: 200 GWRWLIRVASIPGIILIVAFKFIPESARF-NVSTGNTRAALATLERV 245


>gi|166064021 solute carrier family 22 (organic anion transporter),
           member 13 [Homo sapiens]
          Length = 551

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 101/422 (23%), Positives = 172/422 (40%), Gaps = 57/422 (13%)

Query: 79  SLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLV 138
           S++  G L G L+ GPL   +GRK ++L   +      +   F     SFE+ M  R  V
Sbjct: 142 SVFMAGLLVGTLMFGPLCDRIGRKATILAQLLLFTLIGLATAF---VPSFELYMALRFAV 198

Query: 139 GVN-AGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPL 197
               AG+S +   +      P     AV ++   F+     +GQ+V L  L  G + W L
Sbjct: 199 ATAVAGLSFSNVTLLTEWVGPSWRTQAVVLAQCNFS-----LGQMV-LAGLAYGFRNWRL 252

Query: 198 LLASCLVPGALQLASLPLLPESPRYLLIDCGDTEAC-----LAALRRLRGSGDLAGELEE 252
           L  +   PG L       LPES R+LL      EA       A++ R + S +L   + +
Sbjct: 253 LQITGTAPGLLLFFYFWALPESARWLLTRGRMDEAIQLIQKAASVNRRKLSPEL---MNQ 309

Query: 253 LEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGV 312
           L  E+    G       +LF+H  LR+ VT ++       +   DS+  Y  S+  + G 
Sbjct: 310 LVPEKTGPSG----NALDLFRHPQLRK-VTLIIFC-----VWFVDSLGYYGLSL--QVGD 357

Query: 313 PEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSF 372
               +    +  G+ E+     S  +++R GR+   +G    +   G +  + + + +  
Sbjct: 358 FGLDVYLTQLIFGAVEVPARCSSIFMMQRFGRKWSQLG---TLVLGGLMCIIIIFIPADL 414

Query: 373 PWTLYL-----AMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLI 427
           P  + +      MA   AF +S+         + + ELF  + R         L+ I   
Sbjct: 415 PVVVTMLAVVGKMATAAAFTISY---------VYSAELFPTILRQTGM----GLVGIFSR 461

Query: 428 LVGLGFPFIMEALSHFLYVPFLGV----CVCGAIYTGLFLPETKGKTFQEISKELHRLNF 483
           + G+  P ++    +   +P L       V G + T   LPET G+  ++  ++L     
Sbjct: 462 IGGILTPLVILLGEYHAALPMLIYGSLPIVAGLLCT--LLPETHGQGLKDTLQDLELGPH 519

Query: 484 PR 485
           PR
Sbjct: 520 PR 521


>gi|4507001 solute carrier family 22 member 2 [Homo sapiens]
          Length = 555

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 88/420 (20%), Positives = 168/420 (40%), Gaps = 36/420 (8%)

Query: 73  MWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIM 132
           M  L  S   +G   G++  G +A   GRK  LL   +   +A +L   S    ++  ++
Sbjct: 148 MLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCLLTTVLINAAAGVLMAISP---TYTWML 204

Query: 133 LGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGP 192
           + RL+ G+ +     I  + + E   +  R  V +   +   +G+++  + G+   L   
Sbjct: 205 IFRLIQGLVSKAGWLIGYILITEFVGRRYRRTVGIFYQVAYTVGLLV--LAGVAYAL--- 259

Query: 193 QAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG-DLAGELE 251
             W  L  +  +P    L     +PESPR+L+    + EA        + +G  L   L+
Sbjct: 260 PHWRWLQFTVALPNFFFLLYYWCIPESPRWLISQNKNAEAMRIIKHIAKKNGKSLPASLQ 319

Query: 252 ELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAG 311
            L  E    +  +   P  L   R  + +  +++++ +        S   Y   +    G
Sbjct: 320 RLRLEE---ETGKKLNPSFLDLVRTPQIRKHTMILMYNWFT-----SSVLYQGLIMHM-G 370

Query: 312 VPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLM--TCWGSIFTVALCLQ 369
           +    I      +   E   A +  + I+R+GRR        +    C  S+F     + 
Sbjct: 371 LAGDNIYLDFFYSALVEFPAAFMIILTIDRIGRRYPWAASNMVAGAACLASVF-----IP 425

Query: 370 SSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILV 429
               W L + ++C+    ++       +  ++  EL+    R     +C +    M  + 
Sbjct: 426 GDLQW-LKIIISCLGRMGITMAYE---IVCLVNAELYPTFIRNLGVHICSS----MCDIG 477

Query: 430 GLGFPFIMEALSH-FLYVPFLGVCVCGAIYTGL--FLPETKGKTFQEISKELHRLNFPRR 486
           G+  PF++  L++ +L +P +   V G +  GL   LPETKGK   E  +E   +  PR+
Sbjct: 478 GIITPFLVYRLTNIWLELPLMVFGVLGLVAGGLVLLLPETKGKALPETIEEAENMQRPRK 537


>gi|4507005 solute carrier family 22 member 5 [Homo sapiens]
          Length = 557

 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 100/435 (22%), Positives = 181/435 (41%), Gaps = 60/435 (13%)

Query: 76  LIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGR 135
           L +SL+ +G L G+ ++G L+   GRK  L V        + L  FS+   +FEM ++  
Sbjct: 144 LTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGMQTGFSFLQIFSK---NFEMFVVLF 200

Query: 136 LLVGVNAGVSMNIQPMYLG-ESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGP-- 192
           +LVG+   +S  +    LG E   K +R        IF+ LG+ +    G   L   P  
Sbjct: 201 VLVGMGQ-ISNYVAAFVLGTEILGKSVR-------IIFSTLGVCIFYAFGYMVL---PLF 249

Query: 193 ----QAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLA- 247
               + W +LL +  +PG L +A    +PESPR+L+      EA +   +  + +G +  
Sbjct: 250 AYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAAKANGIVVP 309

Query: 248 ------GELEELEEERAACQG-CRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVY 300
                  EL++L  ++          R W +       R VT + ++     L    SV 
Sbjct: 310 STIFDPSELQDLSSKKQQSHNILDLLRTWNI-------RMVTIMSIM-----LWMTISVG 357

Query: 301 AYASSVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGS 360
            +  S+          I      +   E+   V++ ++++ + RR      YS+ T    
Sbjct: 358 YFGLSL--DTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRR------YSMATALFL 409

Query: 361 IFTVALCLQSSFPWTLYLAMACIFAFILSFGIGPA-GVTGILATELFDQMARPAACMVCG 419
             +V L +Q   P   YL  A +   +  FG+  A  +  +   EL+  + R     V  
Sbjct: 410 GGSVLLFMQLVPPDLYYL--ATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSS 467

Query: 420 ALMWIMLILVGLGFPFIMEALSHFLYVPFL---GVCVCGAIYTGLFLPETKGKTFQEISK 476
               +  IL     P+ +   ++  ++P++    + +  AI T LFLPE+ G    +   
Sbjct: 468 TASRLGSIL----SPYFVYLGAYDRFLPYILMGSLTILTAILT-LFLPESFGTPLPDTID 522

Query: 477 ELHRLNFPRRAQGPT 491
           ++ R+   +  + P+
Sbjct: 523 QMLRVKGMKHRKTPS 537


>gi|7662270 synaptic vesicle protein 2B homolog [Homo sapiens]
          Length = 683

 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 44/153 (28%), Positives = 69/153 (45%), Gaps = 14/153 (9%)

Query: 83  LGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVGVNA 142
           LG + GA + G LA  LGRK+ L ++     S A L  F +  G+F   +  RL+ G+  
Sbjct: 156 LGMMAGAFILGGLADKLGRKRVLSMSLAVNASFASLSSFVQGYGAF---LFCRLISGIGI 212

Query: 143 GVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVV--------GLRELLGGP-- 192
           G ++ I   Y  E   +E RG       IF   G +    +        G    +G    
Sbjct: 213 GGALPIVFAYFSEFLSREKRGEHLSWLGIFWMTGGLYASAMAWSIIPHYGWGFSMGTNYH 272

Query: 193 -QAWPLLLASCLVPGALQLASLPLLPESPRYLL 224
             +W + +  C +P  + + +L  +PESPR+LL
Sbjct: 273 FHSWRVFVIVCALPCTVSMVALKFMPESPRFLL 305


>gi|216548223 synaptic vesicle glycoprotein 2 [Homo sapiens]
          Length = 742

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 47/157 (29%), Positives = 70/157 (44%), Gaps = 22/157 (14%)

Query: 83  LGGLFGALLAGPLAITLGRKKSLL----VNNIFVVSAAILFGFSRKAGSFEMIMLGRLLV 138
           LG + GA L G LA  LGR++ LL    VN++F   ++ + G+    G+F   +  RLL 
Sbjct: 213 LGMMVGAFLWGGLADRLGRRQCLLISLSVNSVFAFFSSFVQGY----GTF---LFCRLLS 265

Query: 139 GVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVV--------GLRELLG 190
           GV  G S+ I   Y  E   +E RG       +F  +G V    +        G    +G
Sbjct: 266 GVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGVYAAAMAWAIIPHYGWSFQMG 325

Query: 191 GP---QAWPLLLASCLVPGALQLASLPLLPESPRYLL 224
                 +W + +  C  P    + +L   PESPR+ L
Sbjct: 326 SAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFL 362


>gi|90669191 solute carrier family 22 member 7 isoform b [Homo
           sapiens]
          Length = 548

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 103/423 (24%), Positives = 164/423 (38%), Gaps = 57/423 (13%)

Query: 84  GGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG-VNA 142
           G L GA+  G L+   GR++ LLV     VS  +L   S  + S+ M  + R L G   A
Sbjct: 154 GVLVGAVAFGYLSDRFGRRRLLLVA---YVSTLVLGLASAASVSYVMFAITRTLTGSALA 210

Query: 143 GVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVG--LRELLGGPQAWPLLLA 200
           G ++ + P+ L E    E R    + S+ F   G+++  +VG  +R+       W  LL 
Sbjct: 211 GFTIIVMPLEL-EWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRD-------WRWLLL 262

Query: 201 SCLVPGALQLASLPLLPESPRYLLIDCGDTEA--CLAALRRLRGSGDLAGELEELEEERA 258
           +  +P A  + SL  +PES R+LL      EA   L    RL G         +    + 
Sbjct: 263 AVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAVSKV 322

Query: 259 ACQGCRARRP--WELFQHRALRRQVTSLVVL---------GSAMELCGNDSVYAYASSVF 307
           A      RRP   +LF+   LR      VV+         G ++++ G          +F
Sbjct: 323 AAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQTQLLF 382

Query: 308 RKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTV-AL 366
               +P   + Y  +      L  A          G R+L+    S M  W ++  V   
Sbjct: 383 GAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTRLLV---SSDMKSWSTVLAVMGK 439

Query: 367 CLQSSFPWTLYLAMACIFAFIL-SFGIGPAGVTGILATELFDQMARPAACMVCGALMWIM 425
               +   T YL  + ++  +L   G+G   + G L   L      P A ++ G  +W+ 
Sbjct: 440 AFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSL-----APLAALLDG--VWLS 492

Query: 426 LILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFPR 485
           L  +  G                 G+ +  A  T L LPET+     E  +++ R + P 
Sbjct: 493 LPKLTYG-----------------GIALLAA-GTALLLPETRQAQLPETIQDVERKSAPT 534

Query: 486 RAQ 488
             Q
Sbjct: 535 SLQ 537


>gi|24497497 solute carrier family 22 member 7 isoform a [Homo
           sapiens]
          Length = 546

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 103/423 (24%), Positives = 164/423 (38%), Gaps = 57/423 (13%)

Query: 84  GGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG-VNA 142
           G L GA+  G L+   GR++ LLV     VS  +L   S  + S+ M  + R L G   A
Sbjct: 152 GVLVGAVAFGYLSDRFGRRRLLLVA---YVSTLVLGLASAASVSYVMFAITRTLTGSALA 208

Query: 143 GVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVG--LRELLGGPQAWPLLLA 200
           G ++ + P+ L E    E R    + S+ F   G+++  +VG  +R+       W  LL 
Sbjct: 209 GFTIIVMPLEL-EWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRD-------WRWLLL 260

Query: 201 SCLVPGALQLASLPLLPESPRYLLIDCGDTEA--CLAALRRLRGSGDLAGELEELEEERA 258
           +  +P A  + SL  +PES R+LL      EA   L    RL G         +    + 
Sbjct: 261 AVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAVSKV 320

Query: 259 ACQGCRARRP--WELFQHRALRRQVTSLVVL---------GSAMELCGNDSVYAYASSVF 307
           A      RRP   +LF+   LR      VV+         G ++++ G          +F
Sbjct: 321 AAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQTQLLF 380

Query: 308 RKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTV-AL 366
               +P   + Y  +      L  A          G R+L+    S M  W ++  V   
Sbjct: 381 GAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTRLLV---SSDMKSWSTVLAVMGK 437

Query: 367 CLQSSFPWTLYLAMACIFAFIL-SFGIGPAGVTGILATELFDQMARPAACMVCGALMWIM 425
               +   T YL  + ++  +L   G+G   + G L   L      P A ++ G  +W+ 
Sbjct: 438 AFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSL-----APLAALLDG--VWLS 490

Query: 426 LILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFPR 485
           L  +  G                 G+ +  A  T L LPET+     E  +++ R + P 
Sbjct: 491 LPKLTYG-----------------GIALLAA-GTALLLPETRQAQLPETIQDVERKSAPT 532

Query: 486 RAQ 488
             Q
Sbjct: 533 SLQ 535


>gi|73695465 synaptic vesicle glycoprotein 2C [Homo sapiens]
          Length = 727

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 43/161 (26%), Positives = 68/161 (42%), Gaps = 22/161 (13%)

Query: 79  SLYPLGGLFGALLAGPLAITLGRKKSLL----VNNIFVVSAAILFGFSRKAGSFEMIMLG 134
           S+  LG + GA   G LA  +GRK+SLL    VN  F   ++ + G+          +  
Sbjct: 195 SIVYLGMMVGAFFWGGLADKVGRKQSLLICMSVNGFFAFLSSFVQGYG-------FFLFC 247

Query: 135 RLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVV--------GLR 186
           RLL G   G ++     Y  E   +E RG       +F  +G +    +        G  
Sbjct: 248 RLLSGFGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWS 307

Query: 187 ELLGGP---QAWPLLLASCLVPGALQLASLPLLPESPRYLL 224
             +G      +W + +  C +P    + +L  +PESPR+LL
Sbjct: 308 FSMGSAYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLL 348


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.141    0.434 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,725,848
Number of Sequences: 37866
Number of extensions: 829511
Number of successful extensions: 2555
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 2448
Number of HSP's gapped (non-prelim): 73
length of query: 503
length of database: 18,247,518
effective HSP length: 107
effective length of query: 396
effective length of database: 14,195,856
effective search space: 5621558976
effective search space used: 5621558976
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.