Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 189217919
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|189217919 protein associated with topoisomerase II homolog 1
[Homo sapiens]
(770 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|189217919 protein associated with topoisomerase II homolog 1 ... 1548 0.0
gi|223278366 protein associated with topoisomerase II homolog 2 ... 267 2e-71
gi|119943102 CREB binding protein isoform b [Homo sapiens] 60 6e-09
gi|119943104 CREB binding protein isoform a [Homo sapiens] 60 6e-09
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 59 2e-08
gi|31324577 molecule interacting with Rab13 [Homo sapiens] 58 3e-08
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 57 5e-08
gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho... 57 8e-08
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 56 1e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 56 1e-07
gi|163965366 nascent polypeptide-associated complex alpha subuni... 54 4e-07
gi|11386183 WAS protein family, member 2 [Homo sapiens] 53 9e-07
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 52 3e-06
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 51 4e-06
gi|33356148 formin-like 1 [Homo sapiens] 51 5e-06
gi|13699803 WAS protein family, member 3 [Homo sapiens] 50 8e-06
gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens] 50 8e-06
gi|47132519 Ras association and pleckstrin homology domains 1 is... 50 1e-05
gi|7662302 TBK1 binding protein 1 [Homo sapiens] 49 1e-05
gi|57863314 vacuolar protein sorting 37C [Homo sapiens] 49 2e-05
gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 49 2e-05
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 49 2e-05
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 48 3e-05
gi|151301053 RNA binding motif protein 33 [Homo sapiens] 48 3e-05
gi|166064029 angiomotin isoform 1 [Homo sapiens] 48 3e-05
gi|210032580 SET domain containing 1B [Homo sapiens] 48 3e-05
gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo s... 48 4e-05
gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo sa... 48 4e-05
gi|30794372 polybromo 1 isoform 1 [Homo sapiens] 48 4e-05
gi|93102371 polybromo 1 isoform 2 [Homo sapiens] 48 4e-05
>gi|189217919 protein associated with topoisomerase II homolog 1
[Homo sapiens]
Length = 770
Score = 1548 bits (4007), Expect = 0.0
Identities = 770/770 (100%), Positives = 770/770 (100%)
Query: 1 MFRYESLEDCPLDEDEDAFQGLGEEDEEIDQFNDDTFGSGAVDDDWQEAHERLAELEEKL 60
MFRYESLEDCPLDEDEDAFQGLGEEDEEIDQFNDDTFGSGAVDDDWQEAHERLAELEEKL
Sbjct: 1 MFRYESLEDCPLDEDEDAFQGLGEEDEEIDQFNDDTFGSGAVDDDWQEAHERLAELEEKL 60
Query: 61 PVAVNEQTGNGERDEMDLLGDHEENLAERLSKMVIENELEDPAIMRAVQTRPVLQPQPGS 120
PVAVNEQTGNGERDEMDLLGDHEENLAERLSKMVIENELEDPAIMRAVQTRPVLQPQPGS
Sbjct: 61 PVAVNEQTGNGERDEMDLLGDHEENLAERLSKMVIENELEDPAIMRAVQTRPVLQPQPGS 120
Query: 121 LNSSIWDGSEVLRRIRGPLLAQEMPTVSVLEYALPQRPPQGPEDDRDLSERALPRRSTSP 180
LNSSIWDGSEVLRRIRGPLLAQEMPTVSVLEYALPQRPPQGPEDDRDLSERALPRRSTSP
Sbjct: 121 LNSSIWDGSEVLRRIRGPLLAQEMPTVSVLEYALPQRPPQGPEDDRDLSERALPRRSTSP 180
Query: 181 IIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVRPPMPPRYPAPYGERMSPNQLCSV 240
IIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVRPPMPPRYPAPYGERMSPNQLCSV
Sbjct: 181 IIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVRPPMPPRYPAPYGERMSPNQLCSV 240
Query: 241 PNSSLLGHPFPPSVPPVLSPLQRAQLLGGAQLQPGRMSPSQFARVPGFVGSPLAAMNPKL 300
PNSSLLGHPFPPSVPPVLSPLQRAQLLGGAQLQPGRMSPSQFARVPGFVGSPLAAMNPKL
Sbjct: 241 PNSSLLGHPFPPSVPPVLSPLQRAQLLGGAQLQPGRMSPSQFARVPGFVGSPLAAMNPKL 300
Query: 301 LQGRVGQMLPPAPGFRAFFSAPPSATPPPQQHPPGPGPHLQNLRSQAPMFRPDTTHLHPQ 360
LQGRVGQMLPPAPGFRAFFSAPPSATPPPQQHPPGPGPHLQNLRSQAPMFRPDTTHLHPQ
Sbjct: 301 LQGRVGQMLPPAPGFRAFFSAPPSATPPPQQHPPGPGPHLQNLRSQAPMFRPDTTHLHPQ 360
Query: 361 HRRLLHQRQQQNRSQHRNLNGAGDRGSHRSSHQDHLRKDPYANLMLQREKDWVSKIQMMQ 420
HRRLLHQRQQQNRSQHRNLNGAGDRGSHRSSHQDHLRKDPYANLMLQREKDWVSKIQMMQ
Sbjct: 361 HRRLLHQRQQQNRSQHRNLNGAGDRGSHRSSHQDHLRKDPYANLMLQREKDWVSKIQMMQ 420
Query: 421 LQSTDPYLDDFYYQNYFEKLEKLSAAEEIQGDGPKKERTKLITPQVAKLEHAYKPVQFEG 480
LQSTDPYLDDFYYQNYFEKLEKLSAAEEIQGDGPKKERTKLITPQVAKLEHAYKPVQFEG
Sbjct: 421 LQSTDPYLDDFYYQNYFEKLEKLSAAEEIQGDGPKKERTKLITPQVAKLEHAYKPVQFEG 480
Query: 481 SLGKLTVSSVNNPRKMIDAVVTSRSEDDETKEKQVRDKRRKTLVIIEKTYSLLLDVEDYE 540
SLGKLTVSSVNNPRKMIDAVVTSRSEDDETKEKQVRDKRRKTLVIIEKTYSLLLDVEDYE
Sbjct: 481 SLGKLTVSSVNNPRKMIDAVVTSRSEDDETKEKQVRDKRRKTLVIIEKTYSLLLDVEDYE 540
Query: 541 RRYLLSLEEERPALMDDRKHKICSMYDNLRGKLPGQERPSDDHFVQIMCIRKGKRMVARI 600
RRYLLSLEEERPALMDDRKHKICSMYDNLRGKLPGQERPSDDHFVQIMCIRKGKRMVARI
Sbjct: 541 RRYLLSLEEERPALMDDRKHKICSMYDNLRGKLPGQERPSDDHFVQIMCIRKGKRMVARI 600
Query: 601 LPFLSTEQAADILMTTARNLPFLIKKDAQDEVLPCLLSPFSLLLYHLPSVSITSLLRQLM 660
LPFLSTEQAADILMTTARNLPFLIKKDAQDEVLPCLLSPFSLLLYHLPSVSITSLLRQLM
Sbjct: 601 LPFLSTEQAADILMTTARNLPFLIKKDAQDEVLPCLLSPFSLLLYHLPSVSITSLLRQLM 660
Query: 661 NLPQSAATPALSNPHLTAVLQNKFGLSLLLILLSRGEDLQSSDPATESTQNNQWTEVMFM 720
NLPQSAATPALSNPHLTAVLQNKFGLSLLLILLSRGEDLQSSDPATESTQNNQWTEVMFM
Sbjct: 661 NLPQSAATPALSNPHLTAVLQNKFGLSLLLILLSRGEDLQSSDPATESTQNNQWTEVMFM 720
Query: 721 ATRELLRIPQAALAKPISIPTNLVSLFSRYVDRQKLNLLETKLQLVQGIR 770
ATRELLRIPQAALAKPISIPTNLVSLFSRYVDRQKLNLLETKLQLVQGIR
Sbjct: 721 ATRELLRIPQAALAKPISIPTNLVSLFSRYVDRQKLNLLETKLQLVQGIR 770
>gi|223278366 protein associated with topoisomerase II homolog 2
[Homo sapiens]
Length = 543
Score = 267 bits (683), Expect = 2e-71
Identities = 175/506 (34%), Positives = 267/506 (52%), Gaps = 40/506 (7%)
Query: 266 LLGGAQLQPGRMSPSQFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPSA 325
+LG + S + PG +G LA+++ + L P P + F PS
Sbjct: 66 VLGAVHNTQRALLSSPGVKAPGMLGMSLASLH---FLWQTLDYLSPIPFWPTF----PST 118
Query: 326 TPPPQQHPP---GPGPHL--QNLRSQAPMFRPDTTHLHPQHRRLLHQRQQQNRSQHRNLN 380
+ P Q P P P L L S P F T LHP+H+R+L QQQ SQ
Sbjct: 119 SSPAQHFGPRLPSPDPTLFCSLLTSWPPRFS-HLTQLHPRHQRIL---QQQQHSQ----- 169
Query: 381 GAGDRGSHRSSHQDHLRKDPYANLMLQREKDWVSKIQMMQLQSTDPYLDDFYYQNYFEKL 440
S + + DPYANLM ++EKDWV K+QM+QLQS P LDD+YYQ Y++KL
Sbjct: 170 ----TPSPPAKKPWSQQPDPYANLMTRKEKDWVIKVQMVQLQSAKPRLDDYYYQEYYQKL 225
Query: 441 EKLSAAEEIQGDGPKKERTKLITPQVAKLEHAYKPVQFEGSLGKLTVSSVNNPRKMIDAV 500
EK A EE+ G + E KL+TP + K E V+ EGSLG++ VS+ +PR+ IDAV
Sbjct: 226 EKKQADEELLGRRNRVESLKLVTPYIPKAEAYESVVRIEGSLGQVAVSTCFSPRRAIDAV 285
Query: 501 VTSRSEDDETKEKQVRDKRRKTLVIIEKTYSLLLDVEDYERRYLLSLEEERPALMDDRKH 560
E D + +R + L IEK + LL++E+ + P + + +
Sbjct: 286 PHGTQEQD---IEAASSQRLRVLYRIEKMFLQLLEIEEGWK-----YRPPPPCFSEQQSN 337
Query: 561 KICSMYDNLRGKLPGQERPSDDHFVQIMCIRKGKRMVARILPFLSTEQAADILMTTARNL 620
++ ++ L+ + + D F+Q++ +RKGK +VAR+LPFL +QA IL+ +L
Sbjct: 338 QVEKLFQTLKTQEQNNLEEAADGFLQVLSVRKGKALVARLLPFLPQDQAVTILLAITHHL 397
Query: 621 PFLIKKDAQDEVLPCLLSPFSLLLYHLPSVSITSLLRQLMNLPQSAATPALSNPHLTAVL 680
P L+++D D+ L L P + HL + L+ L LP P S +T VL
Sbjct: 398 PLLVRRDVADQALQMLFKPLGKCISHLTLHELLQGLQGLTLLP-----PGSSERPVTVVL 452
Query: 681 QNKFGLSLLLILLSRGEDLQSSDPATE--STQNNQWTEVMFMATRELLRIPQAALAKPIS 738
QN+FG+SLL LLS GE L S + E ++ + WT+++ + E+ ++P A+LA+P++
Sbjct: 453 QNQFGISLLYALLSHGEQLVSLHSSLEEPNSDHTAWTDMVVLIAWEIAQMPTASLAEPLA 512
Query: 739 IPTNLVSLFSRYVDRQKLNLLETKLQ 764
P+NL+ LF +VD+Q + LE +++
Sbjct: 513 FPSNLLPLFCHHVDKQLVQQLEARME 538
>gi|119943102 CREB binding protein isoform b [Homo sapiens]
Length = 2404
Score = 60.5 bits (145), Expect = 6e-09
Identities = 89/352 (25%), Positives = 125/352 (35%), Gaps = 58/352 (16%)
Query: 111 RPVLQPQPGSLNSSIWDGSEVLRRIRGPLLAQEMPTVSVLEYALP-QRPPQGPEDDRDLS 169
+P QPQP ++ S V R ++ PT V P Q PP E R +
Sbjct: 1866 QPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIE 1925
Query: 170 ERALPRRSTSP--IIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVR----PPMPP- 222
A ++ I S P +GTP QMA S P+P V P MPP
Sbjct: 1926 REAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLN----VPRPNQVSGPVMPSMPPG 1981
Query: 223 ---RYPAPYGERMS--PNQLCSVPNSSLLGHPFPPSVPPVLS------------------ 259
+ P P + M P + S+ + + P PSV P S
Sbjct: 1982 QWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSS 2041
Query: 260 PLQRAQLLGGAQLQPGRMSPSQFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFF 319
P Q+ Q+L + P M+ R +V + LQ + G + P PG
Sbjct: 2042 PQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPG--MQPQPGMHQQP 2099
Query: 320 S----------APPSATPPPQQHPPGPGPHLQNLRSQAPMFRPDTTHLHPQHRRLL---- 365
S P PP QQ G P Q L P P+ ++PQ+R +L
Sbjct: 2100 SLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQL 2159
Query: 366 -----HQRQQQNRSQHRNLNGAGDRGSHRSSHQDHLRKDP--YANLMLQREK 410
Q+QQQ + Q + AG G Q + P Y M Q+++
Sbjct: 2160 LQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQR 2211
Score = 38.5 bits (88), Expect = 0.024
Identities = 54/208 (25%), Positives = 77/208 (37%), Gaps = 29/208 (13%)
Query: 166 RDLSERALPRRSTSPIIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVRPPMPP-RY 224
++L E+ R I+G+ P P PP + P+ VRPP P
Sbjct: 625 KELEEKRRSRLHKQGILGNQPALPAPGAQPP------------VIPQAQPVRPPNGPLSL 672
Query: 225 PAPYGERMSPNQLCSVPNSSLLGH---PFPPSVPPVLSPLQRAQLLGGAQLQPG-RMSPS 280
P RM +Q + N LG+ P P P SP+ + + PG +SPS
Sbjct: 673 PV---NRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPS 729
Query: 281 QFARVPGFVG---SPLAAMNPKLLQGRVGQMLPPAPGFRAF-FSAPPSATPPPQQHPPG- 335
+ + P +G + + A P Q P + G + PP+ T Q PG
Sbjct: 730 RMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGA 789
Query: 336 --PGP--HLQNLRSQAPMFRPDTTHLHP 359
P P L SQ P + LHP
Sbjct: 790 ALPNPLNMLGPQASQLPCPPVTQSPLHP 817
Score = 37.0 bits (84), Expect = 0.069
Identities = 51/208 (24%), Positives = 78/208 (37%), Gaps = 37/208 (17%)
Query: 168 LSERALPRRSTSPIIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVRPPMPPRYPAP 227
++ R +P++S +PP GTP +Q + P Q P+P V M P
Sbjct: 1834 MNTRNVPQQSLPSPTSAPP------GTPTQQPSTPQTPQPPAQPQPSPV--SMSPAGFPS 1885
Query: 228 YGERMSPNQLCSVPNSSLLGHPFPPSVPPVLSPLQRAQLLGGAQLQ-------------P 274
P + + +S + P PP+ PP + Q+ AQ Q P
Sbjct: 1886 VARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPP 1945
Query: 275 GRMSPSQFARVPGFVGSP--LAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPSATPPPQQH 332
GR PG +P L P + G V +PP +A P PQQ
Sbjct: 1946 GRTGMG----TPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQA---------PLPQQQ 1992
Query: 333 P-PGPGPHLQNLRSQAPMFRPDTTHLHP 359
P PG + ++++QA + P + P
Sbjct: 1993 PMPGLPRPVISMQAQAAVAGPRMPSVQP 2020
Score = 35.0 bits (79), Expect = 0.26
Identities = 48/180 (26%), Positives = 68/180 (37%), Gaps = 13/180 (7%)
Query: 169 SERALPRRSTSP--IIGSPPVRAV--PIGTPPKQMAVP----SFTQQILCPKPVHVRPPM 220
++ ALP P I + PVR P+ P +M V SF L + + PM
Sbjct: 643 NQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLP-QAPM 701
Query: 221 PPRYPAPYGERMSPNQLCSVPNSSLLGH--PFPPSVPPVLSPLQRAQLLGGAQLQPGRMS 278
PR +P + N + SVP ++ P PP++ + AQ +Q P
Sbjct: 702 GPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQF 761
Query: 279 PSQFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPSATPPPQQHPPGPGP 338
PS + +G P A + QG+V P P A PP Q P P P
Sbjct: 762 PSSSGAMSVGMGQPPAQTG--VSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTP 819
>gi|119943104 CREB binding protein isoform a [Homo sapiens]
Length = 2442
Score = 60.5 bits (145), Expect = 6e-09
Identities = 89/352 (25%), Positives = 125/352 (35%), Gaps = 58/352 (16%)
Query: 111 RPVLQPQPGSLNSSIWDGSEVLRRIRGPLLAQEMPTVSVLEYALP-QRPPQGPEDDRDLS 169
+P QPQP ++ S V R ++ PT V P Q PP E R +
Sbjct: 1904 QPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIE 1963
Query: 170 ERALPRRSTSP--IIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVR----PPMPP- 222
A ++ I S P +GTP QMA S P+P V P MPP
Sbjct: 1964 REAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLN----VPRPNQVSGPVMPSMPPG 2019
Query: 223 ---RYPAPYGERMS--PNQLCSVPNSSLLGHPFPPSVPPVLS------------------ 259
+ P P + M P + S+ + + P PSV P S
Sbjct: 2020 QWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSS 2079
Query: 260 PLQRAQLLGGAQLQPGRMSPSQFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFF 319
P Q+ Q+L + P M+ R +V + LQ + G + P PG
Sbjct: 2080 PQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPG--MQPQPGMHQQP 2137
Query: 320 S----------APPSATPPPQQHPPGPGPHLQNLRSQAPMFRPDTTHLHPQHRRLL---- 365
S P PP QQ G P Q L P P+ ++PQ+R +L
Sbjct: 2138 SLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQL 2197
Query: 366 -----HQRQQQNRSQHRNLNGAGDRGSHRSSHQDHLRKDP--YANLMLQREK 410
Q+QQQ + Q + AG G Q + P Y M Q+++
Sbjct: 2198 LQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQR 2249
Score = 38.5 bits (88), Expect = 0.024
Identities = 54/208 (25%), Positives = 77/208 (37%), Gaps = 29/208 (13%)
Query: 166 RDLSERALPRRSTSPIIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVRPPMPP-RY 224
++L E+ R I+G+ P P PP + P+ VRPP P
Sbjct: 663 KELEEKRRSRLHKQGILGNQPALPAPGAQPP------------VIPQAQPVRPPNGPLSL 710
Query: 225 PAPYGERMSPNQLCSVPNSSLLGH---PFPPSVPPVLSPLQRAQLLGGAQLQPG-RMSPS 280
P RM +Q + N LG+ P P P SP+ + + PG +SPS
Sbjct: 711 PV---NRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPS 767
Query: 281 QFARVPGFVG---SPLAAMNPKLLQGRVGQMLPPAPGFRAF-FSAPPSATPPPQQHPPG- 335
+ + P +G + + A P Q P + G + PP+ T Q PG
Sbjct: 768 RMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGA 827
Query: 336 --PGP--HLQNLRSQAPMFRPDTTHLHP 359
P P L SQ P + LHP
Sbjct: 828 ALPNPLNMLGPQASQLPCPPVTQSPLHP 855
Score = 37.0 bits (84), Expect = 0.069
Identities = 51/208 (24%), Positives = 78/208 (37%), Gaps = 37/208 (17%)
Query: 168 LSERALPRRSTSPIIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVRPPMPPRYPAP 227
++ R +P++S +PP GTP +Q + P Q P+P V M P
Sbjct: 1872 MNTRNVPQQSLPSPTSAPP------GTPTQQPSTPQTPQPPAQPQPSPV--SMSPAGFPS 1923
Query: 228 YGERMSPNQLCSVPNSSLLGHPFPPSVPPVLSPLQRAQLLGGAQLQ-------------P 274
P + + +S + P PP+ PP + Q+ AQ Q P
Sbjct: 1924 VARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPP 1983
Query: 275 GRMSPSQFARVPGFVGSP--LAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPSATPPPQQH 332
GR PG +P L P + G V +PP +A P PQQ
Sbjct: 1984 GRTGMG----TPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQA---------PLPQQQ 2030
Query: 333 P-PGPGPHLQNLRSQAPMFRPDTTHLHP 359
P PG + ++++QA + P + P
Sbjct: 2031 PMPGLPRPVISMQAQAAVAGPRMPSVQP 2058
Score = 35.0 bits (79), Expect = 0.26
Identities = 48/180 (26%), Positives = 68/180 (37%), Gaps = 13/180 (7%)
Query: 169 SERALPRRSTSP--IIGSPPVRAV--PIGTPPKQMAVP----SFTQQILCPKPVHVRPPM 220
++ ALP P I + PVR P+ P +M V SF L + + PM
Sbjct: 681 NQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLP-QAPM 739
Query: 221 PPRYPAPYGERMSPNQLCSVPNSSLLGH--PFPPSVPPVLSPLQRAQLLGGAQLQPGRMS 278
PR +P + N + SVP ++ P PP++ + AQ +Q P
Sbjct: 740 GPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQF 799
Query: 279 PSQFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPSATPPPQQHPPGPGP 338
PS + +G P A + QG+V P P A PP Q P P P
Sbjct: 800 PSSSGAMSVGMGQPPAQTG--VSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTP 857
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 58.9 bits (141), Expect = 2e-08
Identities = 56/186 (30%), Positives = 70/186 (37%), Gaps = 31/186 (16%)
Query: 158 PPQGPEDDRDLSERALPRRSTSPIIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVR 217
PP+ P +A P ++ P+ G P P+ TPP Q + P
Sbjct: 580 PPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS 639
Query: 218 PPMPP-RYPAPYGERMSPNQLCSVPNSSLLGHPF-PPSVPPVLSPLQRAQLLGGAQLQPG 275
PP+ P P+P +PN L LL PF PP PPV +P + P
Sbjct: 640 PPLSPLATPSP----QAPNALA----VHLLQAPFSPPPSPPVQAPFSPP---ASPPVSPS 688
Query: 276 RMSPSQFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPSATPPPQQHPPG 335
PSQ P PL +PP+P S PSATPPPQ PP
Sbjct: 689 ATPPSQ--APPSLAAPPL--------------QVPPSPPASPPMS--PSATPPPQAPPPL 730
Query: 336 PGPHLQ 341
P LQ
Sbjct: 731 AAPPLQ 736
Score = 45.8 bits (107), Expect = 1e-04
Identities = 61/215 (28%), Positives = 80/215 (37%), Gaps = 44/215 (20%)
Query: 142 QEMPTVSVLEYALPQRPPQGPEDDRDLSERALPRRSTSPIIGSPPVRAVPIGTPPKQMAV 201
Q P ++ +P PP P +S A P P++ +PP++ P +PP + +
Sbjct: 725 QAPPPLAAPPLQVPPSPPASPP----MSPSATPPPRVPPLLAAPPLQVPP--SPPASLPM 778
Query: 202 PSFTQQILCPKPVHVRPP---MPPRYPAPYGERMSPNQLCSVPNSSLLGHPF---PPSVP 255
KP PP PP P P Q P++SL P PP P
Sbjct: 779 SPLA------KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 832
Query: 256 PVLSPLQRAQLLGGAQLQPGRMSPS-QFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPG 314
PVL+ A LL P SP+ Q R P G + P+L L APG
Sbjct: 833 PVLA----APLLQVPPSPPA--SPTLQAPRRPPTPGPDTSVSGPRL-------TLALAPG 879
Query: 315 FRAFFSAPPSATPPPQQHPPG--PGPHLQNLRSQA 347
PP PPP + P GP L S A
Sbjct: 880 -------PP---PPPSRSPSSTLSGPDLAGHSSSA 904
Score = 44.7 bits (104), Expect = 3e-04
Identities = 64/244 (26%), Positives = 80/244 (32%), Gaps = 51/244 (20%)
Query: 145 PTVSVLEYALPQRPPQGPEDDRDLSERALPRRSTSPIIGSPPVRAVP------------- 191
P V L A P + P P +S A P P + +PP++A+P
Sbjct: 755 PRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS 814
Query: 192 --IGTPPKQMAVPSFTQQILCPKPVHVRPPMPPRYPAPYGERM----SPNQLCSVPNSSL 245
P +A P + P+ PP PP P R P+ S P +L
Sbjct: 815 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 874
Query: 246 LGHPFPPSVPPVLSP---LQRAQLLG---GAQLQPGRMSPSQFARVPGFVGSP-----LA 294
P PP PP SP L L G A P + G SP LA
Sbjct: 875 ALAPGPPP-PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELA 933
Query: 295 AMNPK----------LLQGRVGQMLP--------PAPGFRAFF--SAPPSATPPPQQHPP 334
A +P +G G LP A G + P SATP P P
Sbjct: 934 ACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDP 993
Query: 335 GPGP 338
GP P
Sbjct: 994 GPSP 997
Score = 38.1 bits (87), Expect = 0.031
Identities = 48/169 (28%), Positives = 56/169 (33%), Gaps = 27/169 (15%)
Query: 166 RDLSERALPRRSTSPIIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVRPPMPPRYP 225
R LS A P +SP P R P P Q + +P V PP P
Sbjct: 240 RSLSSSATPL--SSPARSGPSARGTPRAPAHPSQPKPKGLQAL---RPPQVTPPRKDAAP 294
Query: 226 APYGERMSPNQLCSVPNSSLLGHPFPPSVPPVLSPLQRAQLLGGAQLQPGRMSPSQFARV 285
A SP L + S P PP +PL P + PS
Sbjct: 295 ALGPLSSSP--LATPSPSGTKARPVPPP-DNAATPL------------PATLPPSPPLAT 339
Query: 286 PGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPSATPPPQQHPP 334
P + P + P L Q LP P APPS T PP Q PP
Sbjct: 340 PLPLAPPSPSAPPSL------QTLPSPPATPPS-QAPPSMTTPPMQAPP 381
Score = 37.0 bits (84), Expect = 0.069
Identities = 59/273 (21%), Positives = 88/273 (32%), Gaps = 33/273 (12%)
Query: 112 PVLQ--PQPGSLNSSIWDGSEVLRRIRGPLLAQEMPTVSVLEYALPQRPPQGPEDDRDLS 169
P LQ P P + S S ++ P Q +P + V ++L Q P LS
Sbjct: 352 PSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQV-PHSLTSPSLQAPPSPLALS 410
Query: 170 ERALPRRSTSPIIG--------SPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVRPPMP 221
SP + SP + +P + + P + + P + PP+
Sbjct: 411 SLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQ 470
Query: 222 PRYPAPYGERMSPNQLCSVPN-SSLLGH-PFPPSVPPVLSPLQRAQLLGGAQLQ--PGRM 277
SP + + SSL H P P ++ PL+ L LQ P +
Sbjct: 471 TSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASL 530
Query: 278 SPSQFARVPGFVGSPLAAMNPKL---------------LQGRVGQMLPPAPGFRAFFSAP 322
+ +P PL + L LQ + P P + + P
Sbjct: 531 TTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATP 590
Query: 323 PSATPPPQQHPP---GPGPHLQNLRSQAPMFRP 352
P PP PP P P L L + P P
Sbjct: 591 PPQAPPALASPPLQGLPSPPLSPLATPPPQAPP 623
>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
Length = 863
Score = 58.2 bits (139), Expect = 3e-08
Identities = 69/259 (26%), Positives = 103/259 (39%), Gaps = 43/259 (16%)
Query: 100 EDPAIMRAVQTRPVLQPQPGSLNSSIWDGSEVLRRIRG---PLLAQEMPTVSVLEYALPQ 156
+DP + VQ P +P P +SS S+ R++ +AQ PT S+ + P
Sbjct: 367 KDPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASL--ESKPY 424
Query: 157 RPPQGPEDDRDLSERALPRRSTSPIIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHV 216
P + E+D++ A P +TSP +G P + P P P+ +
Sbjct: 425 NPFEEEEEDKEEEAPAAPSLATSPALGHP--ESTPKSLHPWYGITPTSS----------- 471
Query: 217 RPPMPPRYPAPYGERMSPNQLCSVPNSSLLGHPFPPSVPP-------VLSPLQRAQLLGG 269
P + PAP SP L ++S L H PPS P LS +Q G
Sbjct: 472 --PKTKKRPAPRAPSASPLAL----HASRLSHSEPPSATPSPALSVESLSSESASQTAGA 525
Query: 270 AQLQP---GRMSPSQFARVPGFVGSPLA-------AMNPKLLQGRVGQMLPPAPGF--RA 317
L+P + S PG G+P++ A + +L++ RV QM +PG R
Sbjct: 526 ELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAPRT 585
Query: 318 FFSAPPSATPPPQQHPPGP 336
S+ P P P P
Sbjct: 586 RGSSGPQPAKPCSGATPTP 604
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 57.4 bits (137), Expect = 5e-08
Identities = 70/243 (28%), Positives = 89/243 (36%), Gaps = 43/243 (17%)
Query: 102 PAIMRAVQTRPVLQPQPGSLNSSIWDGSEVLRRIRGPL-LAQEMPTVSVLEYALPQRPPQ 160
P+ Q P L P S S + ++ PL LA P+ LP PP
Sbjct: 309 PSAALQSQAPPTLPATPHS--------SSLTCQLATPLPLAPPSPSAPPSLQTLPS-PPA 359
Query: 161 GPEDDRDLSERALPRRSTSPIIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVRPPM 220
P S + ++T + SPP+ P+ TPP Q + P PP+
Sbjct: 360 TPPSQATTSLGSPTLQATHSFLPSPPLS--PLATPPPQAPPALALPPLQAPPSPPASPPL 417
Query: 221 PP-RYPAPYGERMSPNQLCSVPNSSLLGHPF-PPSVPPVLSPLQRAQLLGGAQLQPGRMS 278
P P+P +PN L LL PF PP PPV +P + P
Sbjct: 418 SPLATPSP----QAPNALAV----HLLQAPFSPPPSPPVQAPFSPP---ASPPVSPSATP 466
Query: 279 PSQFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPSATPPPQQHPPGPGP 338
PSQ P PL +PP+P S PSATPPPQ PP P
Sbjct: 467 PSQAP--PSLAAPPL--------------QVPPSPPASPPMS--PSATPPPQAPPPLAAP 508
Query: 339 HLQ 341
LQ
Sbjct: 509 PLQ 511
Score = 42.4 bits (98), Expect = 0.002
Identities = 62/213 (29%), Positives = 79/213 (37%), Gaps = 51/213 (23%)
Query: 141 AQEMPTVSVLEYALPQRPPQGPEDDRDLSERALPRRSTSPIIGSPPVRAVPIGTPPKQMA 200
+Q P+++ +P PP P SP PP P+ PP Q+A
Sbjct: 468 SQAPPSLAAPPLQVPPSPPASPP--------------MSPSATPPPQAPPPLAAPPLQLA 513
Query: 201 -VPSFTQQILCPKPVHVRPPMPPRYP--APYGERMSPNQLCSVPNSSLLGHPFPPSVPPV 257
P L P+ P P +P AP+ SP+ S+P S L PP PPV
Sbjct: 514 KPPPQAPPALATPPLQALPSPPASFPGQAPF----SPS--ASLPMSPLATP--PPQAPPV 565
Query: 258 LSPLQRAQLLGGAQLQPGRMSPS-QFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPGFR 316
L+ A LL P SP+ Q R P G + P+L L APG
Sbjct: 566 LA----APLLQVPPSPPA--SPTLQAPRRPPTPGPDTSVSGPRL-------TLALAPG-- 610
Query: 317 AFFSAPPSATPPPQQHPPG--PGPHLQNLRSQA 347
PP PPP + P GP L S A
Sbjct: 611 -----PP---PPPSRSPSSTLSGPDLAGHSSSA 635
Score = 40.4 bits (93), Expect = 0.006
Identities = 66/237 (27%), Positives = 80/237 (33%), Gaps = 48/237 (20%)
Query: 142 QEMPTVSVLEYALPQRPPQGPEDDRDLSERALPRRSTS-----PIIGSPPVRAVPIGTPP 196
Q P ++ L + PPQ P +ALP S P S + P+ TPP
Sbjct: 500 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 559
Query: 197 KQMAVPSFTQQILCPKPVHVRPPMPPRYPAPYGERM----SPNQLCSVPNSSLLGHPFPP 252
Q A P + P+ PP PP P R P+ S P +L P PP
Sbjct: 560 PQ-APP------VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP 612
Query: 253 SVPPVLSP---LQRAQLLG---GAQLQPGRMSPSQFARVPGFVGSP-----LAAMNPKL- 300
PP SP L L G A P + G SP LAA +P
Sbjct: 613 P-PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW 671
Query: 301 ---------LQGRVGQMLPPAP--------GFRAFFSA--PPSATPPPQQHPPGPGP 338
+G G LP P G + P SATP P PGP P
Sbjct: 672 SRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 728
Score = 31.2 bits (69), Expect = 3.8
Identities = 70/275 (25%), Positives = 92/275 (33%), Gaps = 63/275 (22%)
Query: 102 PAIMRAVQTRPVLQPQPGSLNSSIWDGSEVLRRIRGPLLAQEMPTVSVLEYALPQRPPQG 161
PA R + P PG ++S G GPL Q+ +S E + +
Sbjct: 95 PASGRGERAPPAKNTSPGPVSSP---GRASGTTRPGPL-GQKGLRISAEETVARGKATEA 150
Query: 162 PEDDRDLSERALPRRSTSPIIGSPPVRAVPIGTPPKQMAVPSFTQ--QILCPKPVHVRPP 219
P+ LS A RR TS G P GTP MA S ++ P+P P
Sbjct: 151 PKRSA-LSAGA--RRDTS---GPTP------GTPSPAMARRSRAAGTEVGLPRPAPSARP 198
Query: 220 MPPRYPAPYGERMSPNQLCSVPNSSLLGHPFPPSVPPVLSPLQRAQLLGGAQLQPGRMSP 279
PP P + S + P P + +R GG +P S
Sbjct: 199 RPPTE--------GPRKSVSSASEHSTTEPSPAA--------RRRPSAGGGLQRPASRSL 242
Query: 280 SQFARV--------PGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPSATPPPQQ 331
S A P G+P A +P P G +A PP TPP +
Sbjct: 243 SSSATPLSSPARSGPSARGTPRAPAHPSQ---------PKPKGLQAL--RPPQVTPPRKD 291
Query: 332 HPPGPGPHLQN----------LRSQAPMFRPDTTH 356
P GP + L+SQAP P T H
Sbjct: 292 AAPALGPLSSSPLATPSPSAALQSQAPPTLPATPH 326
>gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo
sapiens]
Length = 406
Score = 56.6 bits (135), Expect = 8e-08
Identities = 56/171 (32%), Positives = 73/171 (42%), Gaps = 37/171 (21%)
Query: 180 PIIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVRPPMPPRYPAPYGERMSP----N 235
P + PPV VP PP+ VP + P+P PMPP P P G RM+P
Sbjct: 239 PQLPRPPVLPVP-PMPPRPPMVP------MPPRPPIA--PMPPMAPVPPGSRMAPVPPGP 289
Query: 236 QLCSVPNSSLLGHPFPPSVP----PVLSPLQRAQLLGGAQLQPG----RMSPSQ-FARVP 286
++ VP P+PP P P ++P+ + A + PG R+ P ARVP
Sbjct: 290 RMAPVP-------PWPPMAPVPPWPPMAPVPTGPPM--APVPPGPPMARVPPGPPMARVP 340
Query: 287 GFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPSATPPPQQHPPGPG 337
G P+A + P G LPP P PP A PP+ H P G
Sbjct: 341 P--GPPMAPLPP----GPPMAPLPPGPPMAPLPPGPPMAPLPPRSHVPHTG 385
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
sapiens]
Length = 1636
Score = 56.2 bits (134), Expect = 1e-07
Identities = 63/216 (29%), Positives = 84/216 (38%), Gaps = 30/216 (13%)
Query: 145 PTVSVLEYALPQRPPQGPEDD--RDLSERALPRRSTSPIIGSPPVRAVPIGTPPKQMAVP 202
P S E A+ RP D + PR + +P +PP P+ PP Q
Sbjct: 866 PQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTP---APPPPCFPV--PPPQPLPT 920
Query: 203 SFTQQILCPKPV----HVRPPMPPRYPAPYGERMSPN-QLCSVPNSSLLGHPFPPSVPPV 257
+T +P+ H +P +PAP R+ P Q P+ S P PP P
Sbjct: 921 PYTYPAGAKQPIPAQHHFSSGIPAGFPAP---RIGPQPQPHPQPHPSQAFGPQPPQQP-- 975
Query: 258 LSPLQRAQLLGGAQLQPGRM---SPSQFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPG 314
PLQ L PG + SP +A PG +G P ++ +L G LP G
Sbjct: 976 -LPLQHPHLF--PPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSG 1032
Query: 315 FRAFFSAPPSATPPPQQHPP---GPGPHLQNLRSQA 347
F PS PP HPP GP P + + QA
Sbjct: 1033 ALPF----PSPGPPQPPHPPLAYGPAPSTRPMGPQA 1064
Score = 42.0 bits (97), Expect = 0.002
Identities = 67/240 (27%), Positives = 86/240 (35%), Gaps = 43/240 (17%)
Query: 131 VLRRIRGPLLAQEMPTVSVLEYALPQRPPQGPEDDRDLSERALPRRSTSPII--GSPPVR 188
+L R + A+E +L+ L ++PP P + L LPRR S + G PP
Sbjct: 689 LLERTQSTCQAREAARQQLLDRELKKKPPPRPTAPKPL----LPRREESEAVEAGDPPEE 744
Query: 189 AVPIGTPPKQMAVPSFTQQIL-CPKPVHVRP-PMP------PRY---PAPYGERMSPNQL 237
+ PP +A P L P+H P P P P Y P P G P QL
Sbjct: 745 LRSL--PPDMVAGPRLPDTFLGSATPLHFPPSPFPSSTGPGPHYLSGPLPPGTYSGPTQL 802
Query: 238 CS-----------VPNSSLLGHPFPPSVP-----PVLSP---LQRAQLLGGAQLQPGRMS 278
P +L +P P P P SP + + +G P
Sbjct: 803 IQPRAPGPHAMPVAPGPAL--YPAPAYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGL 860
Query: 279 PSQFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPSATPPPQQHPPGPGP 338
PS A P F G P AM + V + P P A P A PPP P P P
Sbjct: 861 PS--APPPQFSG-PELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQP 917
Score = 33.9 bits (76), Expect = 0.59
Identities = 66/261 (25%), Positives = 81/261 (31%), Gaps = 76/261 (29%)
Query: 173 LPRRSTSPIIGSPPVRAVPIGTP-PKQMAVPSFTQQILCPKPVHVRPP-----MPPRYPA 226
+P +P IG P P P P Q P QQ L + H+ PP +PP+ P
Sbjct: 942 IPAGFPAPRIGPQPQ---PHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPY 998
Query: 227 PYGERMSPNQLCSVPNSSLLGHPFPPSVPPVL-SPLQRAQLLGGAQLQ------------ 273
PY P +LG P PP + P Q L
Sbjct: 999 PYA-----------PQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHP 1047
Query: 274 PGRMSPSQFARVPGFVGSPLAAMNPKLLQGRVGQMLP---------PAPGFRAFFSAPPS 324
P P+ R G +PL P GQ P P+PG PP+
Sbjct: 1048 PLAYGPAPSTRPMGPQAAPLTIRGPS----SAGQSTPSPHLVPSPAPSPGPGPVPPRPPA 1103
Query: 325 ATPPP----------------------QQHPPGPGPHLQNLR-SQAPMFRPDTTHL---- 357
A PPP Q P G P LQ + A RP L
Sbjct: 1104 AEPPPCLRRGAAAADLLSSSPESQHGGTQSPGGGQPLLQPTKVDAAEGRRPQALRLIERD 1163
Query: 358 ---HPQHRRLLHQRQQQNRSQ 375
HP+ R L Q + R Q
Sbjct: 1164 PYEHPERLRQLQQELEAFRGQ 1184
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 55.8 bits (133), Expect = 1e-07
Identities = 63/217 (29%), Positives = 79/217 (36%), Gaps = 44/217 (20%)
Query: 137 GPLLAQEMPTVSVLEYALPQRPPQGPEDDRDLSERALPRRSTSPIIGSPPVRAV------ 190
GPL + + T S + P P P S A P + +GSP ++A
Sbjct: 288 GPLSSSPLATPSP---SAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPS 344
Query: 191 ----PIGTPPKQMAVPSFTQQILCPKPVHVRPPMPP-RYPAPYGERMSPNQLCSVPNSSL 245
P+ TPP Q + P PP+ P P+P +PN L L
Sbjct: 345 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP----QAPNALAV----HL 396
Query: 246 LGHPF-PPSVPPVLSPLQRAQLLGGAQLQPGRMSPSQFARVPGFVGSPLAAMNPKLLQGR 304
L PF PP PPV +P + P PSQ P PL
Sbjct: 397 LQAPFSPPPSPPVQAPFSPP---ASPPVSPSATPPSQAP--PSLAAPPL----------- 440
Query: 305 VGQMLPPAPGFRAFFSAPPSATPPPQQHPPGPGPHLQ 341
+PP+P S PSATPPPQ PP P LQ
Sbjct: 441 ---QVPPSPPASPPMS--PSATPPPQAPPPLAAPPLQ 472
Score = 42.4 bits (98), Expect = 0.002
Identities = 62/213 (29%), Positives = 79/213 (37%), Gaps = 51/213 (23%)
Query: 141 AQEMPTVSVLEYALPQRPPQGPEDDRDLSERALPRRSTSPIIGSPPVRAVPIGTPPKQMA 200
+Q P+++ +P PP P SP PP P+ PP Q+A
Sbjct: 429 SQAPPSLAAPPLQVPPSPPASPP--------------MSPSATPPPQAPPPLAAPPLQLA 474
Query: 201 -VPSFTQQILCPKPVHVRPPMPPRYP--APYGERMSPNQLCSVPNSSLLGHPFPPSVPPV 257
P L P+ P P +P AP+ SP+ S+P S L PP PPV
Sbjct: 475 KPPPQAPPALATPPLQALPSPPASFPGQAPF----SPS--ASLPMSPLATP--PPQAPPV 526
Query: 258 LSPLQRAQLLGGAQLQPGRMSPS-QFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPGFR 316
L+ A LL P SP+ Q R P G + P+L L APG
Sbjct: 527 LA----APLLQVPPSPPA--SPTLQAPRRPPTPGPDTSVSGPRL-------TLALAPG-- 571
Query: 317 AFFSAPPSATPPPQQHPPG--PGPHLQNLRSQA 347
PP PPP + P GP L S A
Sbjct: 572 -----PP---PPPSRSPSSTLSGPDLAGHSSSA 596
Score = 40.4 bits (93), Expect = 0.006
Identities = 66/237 (27%), Positives = 80/237 (33%), Gaps = 48/237 (20%)
Query: 142 QEMPTVSVLEYALPQRPPQGPEDDRDLSERALPRRSTS-----PIIGSPPVRAVPIGTPP 196
Q P ++ L + PPQ P +ALP S P S + P+ TPP
Sbjct: 461 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 520
Query: 197 KQMAVPSFTQQILCPKPVHVRPPMPPRYPAPYGERM----SPNQLCSVPNSSLLGHPFPP 252
Q A P + P+ PP PP P R P+ S P +L P PP
Sbjct: 521 PQ-APP------VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP 573
Query: 253 SVPPVLSP---LQRAQLLG---GAQLQPGRMSPSQFARVPGFVGSP-----LAAMNPKL- 300
PP SP L L G A P + G SP LAA +P
Sbjct: 574 P-PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW 632
Query: 301 ---------LQGRVGQMLPPAP--------GFRAFFSA--PPSATPPPQQHPPGPGP 338
+G G LP P G + P SATP P PGP P
Sbjct: 633 SRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 689
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 54.3 bits (129), Expect = 4e-07
Identities = 63/222 (28%), Positives = 78/222 (35%), Gaps = 30/222 (13%)
Query: 142 QEMPTVSVLEYALPQRPPQGPEDDRDLSERALPRRSTSP-----------IIGSPPVRAV 190
+E PT SV+ P+ +GP AL S+SP I SP +
Sbjct: 883 KETPTPSVVNLPFPK---EGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGA 939
Query: 191 PI---GTPPKQMAVPSFTQQILCPKPVHVRPPMPPRYPAPYGERMSPNQLCSVPNSSLLG 247
P TPP P+ P P PP P PA + +P + P S G
Sbjct: 940 PTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSP-KG 998
Query: 248 HPFPPS-----VPPVLSPLQRAQLLGGAQLQPGRMSPSQFARVPGFVGSPLAAMNPKLLQ 302
P PS PP ++P G +P A P GSP A PK
Sbjct: 999 GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPA-ATPPSPKGSPAATPLPKGAP 1057
Query: 303 GRVGQMLPPAPGFRAFFS-----APPSATPP-PQQHPPGPGP 338
LP G A S PP+ATPP P+ P P P
Sbjct: 1058 TTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP 1099
Score = 43.1 bits (100), Expect = 0.001
Identities = 47/163 (28%), Positives = 54/163 (33%), Gaps = 20/163 (12%)
Query: 191 PIGTPPKQMAVPSFTQQILCPKPVHVRPPMP---PRYPAPYGERMSPNQLCSVPNSSLLG 247
P TPP P+ P P PP P P P+P G P P S
Sbjct: 966 PAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAA 1025
Query: 248 HPFPP--SVPPVLSPLQ------RAQLLGGAQLQPGRMSPSQFA--RVPGFVGSPLA-AM 296
PFP S PP +P L GA P PS P G+P A
Sbjct: 1026 TPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAA 1085
Query: 297 NPKLLQGRVGQMLPPAPGFRAFFSAPPSATPPPQQHPPGPGPH 339
P +G G P G PP+ATPP + PH
Sbjct: 1086 TPPSPKG--GPATPSPKGA----PMPPAATPPSPKGGLATPPH 1122
Score = 42.4 bits (98), Expect = 0.002
Identities = 43/159 (27%), Positives = 54/159 (33%), Gaps = 13/159 (8%)
Query: 183 GSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVRPPMP---PRYPAPYGERMSPNQLCS 239
G+P A + +P A PS P P PP P P P+P G M P
Sbjct: 1055 GAPTTPAATLPSPKGGPATPSLKG---APTPPAATPPSPKGGPATPSPKGAPMPPAATPP 1111
Query: 240 VPNSSLL--GHPFPPSVPPVLSPLQRAQLLGGAQLQPGRMSPSQFARVPGFVGSPLAAMN 297
P L H P+ P P + GG P + +P+ A P LA
Sbjct: 1112 SPKGGLATPPHKGAPTTPAATPPSPK----GGLATPPPKGAPTTPAATPPSPKGGLATPP 1167
Query: 298 PKLLQGRVGQMLPPAPGFRAFFSAPPSATPPPQQHPPGP 336
PK PP+P +P A P PP P
Sbjct: 1168 PKGAP-TTPAATPPSPKGGLATPSPKGAPTTPAATPPSP 1205
Score = 38.5 bits (88), Expect = 0.024
Identities = 55/218 (25%), Positives = 72/218 (33%), Gaps = 63/218 (28%)
Query: 177 STSPIIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVRPPMPPRYPAPYGERMSPNQ 236
+TSP G+P P TPP P P P V PP P + +P
Sbjct: 1302 ATSPPKGAP---TPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSP---------KGTPTL 1349
Query: 237 LCSVPNSSLLGHPFPPS-----VPPVLSPLQRAQLLGGAQLQPGRMSPSQFARVPGFVGS 291
+ P+S G P PS PP +P + GG + P SP + +P G
Sbjct: 1350 PATTPSSK--GGPTTPSSKEGPTPPAATPSHK----GGPAMTP--PSPKRGPAIPSPKGD 1401
Query: 292 PL-----------AAMNPKLLQGRV----GQMLPPAPGFRAFFSAP-------------- 322
P A P +G G + PPA + AP
Sbjct: 1402 PTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSS 1461
Query: 323 ------PSATPPPQQHPPGPGPHLQNLRSQAPMFRPDT 354
P+ TPP + PP P Q S +P P T
Sbjct: 1462 KGDPTLPAVTPPSPKEPPAP---KQVATSSSPKKAPAT 1496
Score = 38.1 bits (87), Expect = 0.031
Identities = 44/169 (26%), Positives = 59/169 (34%), Gaps = 21/169 (12%)
Query: 177 STSPIIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVRPPMPPRYPAPYGERMSPNQ 236
+T P G+P A +P +A PS P P P+P G +P
Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1223
Query: 237 LCSVPNSSLLGHPFP---PSVPPVLSPLQRAQLLGGAQLQPGRMSPSQFARVPGFVGSPL 293
P L P P P+ P P + GG P + +P+ A P + L
Sbjct: 1224 TPPSPKGGL-ATPSPKGAPTTPAATPPSPK----GGPATPPPKGAPTPPAATPPSLKGGL 1278
Query: 294 A------AMNPKLLQGRVGQMLPPAPGFRAFFSAPPSATPPPQQHPPGP 336
A A NP ++ PP+P S P A PP PP P
Sbjct: 1279 ATPPHKGAPNPAVVT-------PPSPKGGPATSPPKGAPTPPAATPPSP 1320
Score = 38.1 bits (87), Expect = 0.031
Identities = 44/189 (23%), Positives = 63/189 (33%), Gaps = 36/189 (19%)
Query: 155 PQRPPQGPEDDRDLSERALPRRSTSPIIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPV 214
P P P + P+ + +P +PP + TPP + A P P
Sbjct: 1241 PTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGA----------PNPA 1290
Query: 215 HVRPPMPPRYPAPYGERMSPNQLCSVPNSSLLGHPFPP----SVPPVLSPLQRAQLLGGA 270
V PP P PA + +P + P S PP PP ++P
Sbjct: 1291 VVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTP---------- 1340
Query: 271 QLQPGRMSPSQFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPSATPP-P 329
+ +P+ A P G P P +G P P P+ TPP P
Sbjct: 1341 --PSPKGTPTLPATTPSSKGGP---TTPSSKEG------PTPPAATPSHKGGPAMTPPSP 1389
Query: 330 QQHPPGPGP 338
++ P P P
Sbjct: 1390 KRGPAIPSP 1398
Score = 35.8 bits (81), Expect = 0.15
Identities = 42/192 (21%), Positives = 65/192 (33%), Gaps = 12/192 (6%)
Query: 154 LPQRPPQGPEDDRDLSERALPRRS--TSPIIGSPPVRAVPIGTPPKQ-MAVPSFTQQILC 210
+P P + P A P + T P + ++ P + PK A PS
Sbjct: 1408 IPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTL 1467
Query: 211 PKPVHVRPPMPPRYPAPYGERMSPNQLCSVPNSSLLGHPFPPSVPP------VLSPLQRA 264
P V PP P PAP S + + + +G P P+V P +P R
Sbjct: 1468 PA---VTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRR 1524
Query: 265 QLLGGAQLQPGRMSPSQFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPS 324
+ + +P+ A + + +PK PA S+PP+
Sbjct: 1525 DPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPA 1584
Query: 325 ATPPPQQHPPGP 336
TP + P P
Sbjct: 1585 VTPSTYKGAPSP 1596
Score = 34.7 bits (78), Expect = 0.34
Identities = 46/199 (23%), Positives = 58/199 (29%), Gaps = 24/199 (12%)
Query: 145 PTVSVLEYALPQRP------PQGPEDDRDLSERALPRRSTSPIIGSPPVRAVPIGTPPKQ 198
P + L P P P+G L P +T P P P G P
Sbjct: 1047 PAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPP 1106
Query: 199 MAVPSFTQQILCPKPVHVRPPMPPRY-PAPYGERMSPNQLCSVPNSSLLGHPFPPSVPPV 257
A P + L P P P P+P G +P PP P
Sbjct: 1107 AATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATP----------------PPKGAPT 1150
Query: 258 LSPLQRAQLLGGAQLQPGRMSPSQFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRA 317
GG P + +P+ A P LA +PK PP+P
Sbjct: 1151 TPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAP-TTPAATPPSPKGGL 1209
Query: 318 FFSAPPSATPPPQQHPPGP 336
+P A P PP P
Sbjct: 1210 ATPSPKGAPTTPAATPPSP 1228
Score = 30.4 bits (67), Expect = 6.5
Identities = 35/133 (26%), Positives = 47/133 (35%), Gaps = 6/133 (4%)
Query: 218 PPMPPRYPAPYGERMSPNQLCSVPNSSLLGHPFPPSVPPVLSPLQRAQLLGGAQLQPGRM 277
P P P E ++ ++ LG P P++PP SP + L A
Sbjct: 10 PATEQELPQPQAETAVLPMSSALSVTAALGQP-GPTLPPPCSPAPQQCPLSAANQASPFP 68
Query: 278 SPSQFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPSATPPPQQHPPGPG 337
SPS A P V P ++ L G P AP F PP + P
Sbjct: 69 SPSTIASTPLEVPFPQSSSGTALPLGTA----PEAPTFLPNLIGPPISPAALALASPMIA 124
Query: 338 PHLQNL-RSQAPM 349
P L+ S AP+
Sbjct: 125 PTLKGTPSSSAPL 137
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 53.1 bits (126), Expect = 9e-07
Identities = 61/196 (31%), Positives = 73/196 (37%), Gaps = 51/196 (26%)
Query: 145 PTVSVLEYALPQRPPQG--PEDDRDLSERALPRRSTSPIIGSPPVRAVPIGTPPKQMAVP 202
P+ S E LP P + P D++ S A P+RS S + S P A P+G+PP
Sbjct: 258 PSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRS-SVVSPSHPPPAPPLGSPPG----- 311
Query: 203 SFTQQILCPKPVHVRPPMPPRYPAPYGERMSPNQLCSVPNSSLLGHPFPPSVPPVLSPLQ 262
PKP PP PP P P ++G P PP PPV
Sbjct: 312 --------PKPGFAPPPAPPPPPPP-----------------MIGIPPPP--PPVGF--- 341
Query: 263 RAQLLGGAQLQPGRMSPSQFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFFSAP 322
G+ P SP F P F P P LPP P + AP
Sbjct: 342 ------GSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADY----PTLPPPPLSQPTGGAP 391
Query: 323 PSATPPPQQHPPGPGP 338
P PPP PPGP P
Sbjct: 392 PPPPPPP---PPGPPP 404
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 51.6 bits (122), Expect = 3e-06
Identities = 65/244 (26%), Positives = 91/244 (37%), Gaps = 43/244 (17%)
Query: 133 RRIRGPLLAQEMPTVSVLEYA------LPQRP--PQGPEDDRDLSERALPRRSTSPIIGS 184
+ I GPL+ P + A P RP P P LP P+ S
Sbjct: 138 KTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLP----PPLPSS 193
Query: 185 PPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVRPPMPPRYPAPYGERMSPNQLCSVPNSS 244
P++ P+ +PP + + ++ P PV PP PP P P + P + S + +
Sbjct: 194 SPIKT-PLVSPPGPLTKGNLP--VVAP-PVPCAPPPPPPPPPPTPPPLPPASVLS--DKA 247
Query: 245 LLGHPFPPSVPPVLSPLQRAQLLGGAQLQPGRMSPSQFARVPGFVGSPL---AAMNPKLL 301
+ P +PP+ PL G L+ SP+Q A+ P PL A+ +P
Sbjct: 248 VKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSP--- 304
Query: 302 QGRVGQMLPPAPGFRAFFSAPPSATP-------PPQQH----------PPGPGPHLQNLR 344
R PP PG + PP P PPQ+ PPG P LQ R
Sbjct: 305 --RASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKR 362
Query: 345 SQAP 348
P
Sbjct: 363 HGRP 366
Score = 42.0 bits (97), Expect = 0.002
Identities = 50/200 (25%), Positives = 73/200 (36%), Gaps = 32/200 (16%)
Query: 157 RPPQGPEDDRDLSERALPRRSTSPIIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHV 216
R P ++ +S +P SP +G+ T P + VP+ P P +
Sbjct: 129 RAPSPRLPNKTISGPLIP--PASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPL 186
Query: 217 RPPMPPRYP------APYGERMSPNQLCSVPNSSLLGHPFPPSVPPVLSPLQRAQLLGGA 270
PP+P P +P G N P P PP PP PL A +L
Sbjct: 187 PPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDK 246
Query: 271 QLQPGRMSPSQFARVPGFVGSPLAAMNPKLLQGRVGQMLPPA--PGFRAFFSAPPSATPP 328
++P +++P +P PL +LPP PG + A P++
Sbjct: 247 AVKP-QLAPLHLPPIP----PPL-------------PLLPPCGYPGLK----AEPASPAQ 284
Query: 329 PQQHPPGPGPHLQNLRSQAP 348
Q PP P P L S +P
Sbjct: 285 DAQEPPAPPPPLPPYASCSP 304
Score = 33.5 bits (75), Expect = 0.77
Identities = 35/142 (24%), Positives = 51/142 (35%), Gaps = 25/142 (17%)
Query: 218 PPMPPRYPAPYGERMSPNQLCSVPNSSLLGHPFPPSVPPVLSPLQRAQLLGGAQLQPGRM 277
P +PP P + + P + P PP+ PP PL P
Sbjct: 143 PLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLP-----------PPLP 191
Query: 278 SPSQFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPSATPPPQQHPPGPG 337
S S + +PL + L +G + + PP P + PP PPP PP P
Sbjct: 192 SSSP-------IKTPLVSPPGPLTKGNLPVVAPPVP-----CAPPPPPPPPPPTPPPLPP 239
Query: 338 PHLQNLRSQAPMFRPDTTHLHP 359
+ + ++ P P HL P
Sbjct: 240 ASVLSDKAVKPQLAP--LHLPP 259
Score = 30.8 bits (68), Expect = 5.0
Identities = 29/102 (28%), Positives = 38/102 (37%), Gaps = 14/102 (13%)
Query: 256 PVLSPLQRAQLLGGAQLQ-PGRMSPSQFARVPGFVGSPLAAMNPKLLQGR----VGQMLP 310
PVL P + + GG Q PG +PS G + +P+L + P
Sbjct: 107 PVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAP 166
Query: 311 PAPGFRAFFSAPPSATPPPQQHPPGPGPHLQNLRSQAPMFRP 352
P P A PPP PP P P L S +P+ P
Sbjct: 167 PRPNVPA---------PPPPTPPPPPPPLPPPLPSSSPIKTP 199
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 51.2 bits (121), Expect = 4e-06
Identities = 64/230 (27%), Positives = 91/230 (39%), Gaps = 53/230 (23%)
Query: 137 GPLLAQEMPTVSVLEY-----ALPQRPPQGPEDDRDLSERAL-PRRSTSPIIGSP----- 185
GP+L Q +P++ + LP P L + P S +P++ P
Sbjct: 659 GPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMP 718
Query: 186 --PVRAVPIGTPPKQMAVPSFTQQILCPKPVHVRPPMPPRYPAPYGERMSPNQLCSVPNS 243
P + P G P +A P+ Q+L P+PV P+PP P PY ++P +
Sbjct: 719 TGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLP-PY---LAP--------A 766
Query: 244 SLLGHPFPPSVPPVLSPLQRAQLLGGAQLQPGRMSPSQFARVPGFVG-SPLAAMN--PKL 300
S +G P L PLQ Q A LQP P Q +P +PLA ++ P
Sbjct: 767 SQVG------APAQLKPLQMPQ----APLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPA 816
Query: 301 LQGRVGQMLPPAPGFRAFFSA----------PPSATPPPQQ-----HPPG 335
L +PP P + F A PP++ P Q HPPG
Sbjct: 817 LPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPG 866
Score = 46.6 bits (109), Expect = 9e-05
Identities = 68/228 (29%), Positives = 90/228 (39%), Gaps = 40/228 (17%)
Query: 138 PLLAQEMPTVSVLEY-----ALPQRP------PQGPEDDRDLSERALPRRSTSPIIGSPP 186
PLLA P V+ L LP +P PQ D S P + + +PP
Sbjct: 885 PLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPS----PHHTVQNMRATPP 940
Query: 187 VRAVPIG-TPPKQMAVPSFTQQILCPKPVHVRPPMPPRYPAPY--GERMSPNQLCSVPNS 243
A+P T P Q +P Q L P+PV PP P R P P + M P Q P
Sbjct: 941 QPALPPQPTLPPQPVLPP--QPTLPPQPV--LPPQPTRPPQPVLPPQPMLPPQPVLPPQP 996
Query: 244 SLLGHPFP--PSVPPVLSPLQRAQLLGGAQLQPGRMSP---SQFARVPGFVGSPLAAMNP 298
+L P P P +P +P G+Q+ G +P A+VP P A ++P
Sbjct: 997 ALPVRPEPLQPHLPEQAAPAATP----GSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSP 1052
Query: 299 KL---LQGRVGQMLPPAPGFRAFFSAPPSATPP------PQQHPPGPG 337
L L ++LP P A SA + P P +PP PG
Sbjct: 1053 PLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPG 1100
Score = 35.4 bits (80), Expect = 0.20
Identities = 61/242 (25%), Positives = 92/242 (38%), Gaps = 46/242 (19%)
Query: 138 PLLAQEMPTVSVLEYALPQRPPQGPEDDRDLSERALPRRSTSPIIGSPPVRAVPIGTPP- 196
P ++PT +V P PPQ L A P SP + P++AV + PP
Sbjct: 814 PPALPDLPTATVP----PVPPPQYFSPAVILPSLAAPLPPASPAL---PLQAVKLPHPPG 866
Query: 197 KQMAVPSFTQQILCPKPVH---VRPP-------------MP--PRYPAPYGERMSPNQLC 238
+A+P T P + V PP +P P YPA + + M+P +
Sbjct: 867 APLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQ-MAPTDVP 925
Query: 239 SVPN---SSLLGHPFPPSVPPVLSPLQRAQLLGGAQLQPGRMSPSQFARVPGFVGSPLAA 295
P+ ++ P P++PP + + L L P + P Q R P V P
Sbjct: 926 PSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPM 985
Query: 296 MNPKLLQGRVGQMLPPAPGFRAF---------FSAPPSATPPPQQHPPGPGPHLQNLRSQ 346
+ P+ +LPP P A P+ATP Q P P+ ++ +Q
Sbjct: 986 LPPQ-------PVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQ 1038
Query: 347 AP 348
P
Sbjct: 1039 VP 1040
Score = 34.7 bits (78), Expect = 0.34
Identities = 68/251 (27%), Positives = 88/251 (35%), Gaps = 46/251 (18%)
Query: 114 LQPQPGSLNSSIWDGSEV--------LRRIRGPL--LAQEMPTVSVLEYALPQRPPQGPE 163
LQP P L + S+V L+ + PL LAQ P + +P PP P
Sbjct: 752 LQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMP----PIPVVPPITPL 807
Query: 164 DDRDLSERALPRRSTSPIIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVRPPMPP- 222
D ALP T+ + PPV PP Q F+ ++ P PP P
Sbjct: 808 AGIDGLPPALPDLPTATV---PPV-------PPPQY----FSPAVILPSLAAPLPPASPA 853
Query: 223 ------RYPAPYGERMSPNQLCSVPNSSL---LGHPFPPSVPPVLSPLQRAQLLGGA--- 270
+ P P G ++ VPN+ L PP V + AQL G
Sbjct: 854 LPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYP 913
Query: 271 ----QLQPGRMSPSQFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPSAT 326
Q+ P + PS V +P P +LPP P PP T
Sbjct: 914 AAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPT 973
Query: 327 PPPQQ-HPPGP 336
PPQ PP P
Sbjct: 974 RPPQPVLPPQP 984
Score = 30.8 bits (68), Expect = 5.0
Identities = 46/158 (29%), Positives = 58/158 (36%), Gaps = 33/158 (20%)
Query: 211 PKPVHVRPPMPPRYPAPYGERMS----PNQLCSVPNSSLLG---------HPFPPSVPPV 257
P P+ PP + APY +++S P+ L S S G P PS PPV
Sbjct: 1332 PLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPV 1391
Query: 258 LS-PLQRAQLLGGAQLQPGRMSPSQFARVPGF---------VGSPLAAMN--PKLLQGRV 305
+ P A +P + SQ A PG PLA + P +Q V
Sbjct: 1392 TALPQDGAAPATSTMPEPASGTASQ-AGGPGTPQGLTSELETSQPLAETHEAPLAVQPLV 1450
Query: 306 GQMLPPAPGFRAF----FSAPPSATPPPQQHPPGPGPH 339
+ P P A SAP PPP P P PH
Sbjct: 1451 VGLAPCTPAPEAASTRDASAPREPLPPP---APEPSPH 1485
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 50.8 bits (120), Expect = 5e-06
Identities = 71/310 (22%), Positives = 110/310 (35%), Gaps = 69/310 (22%)
Query: 28 EIDQFNDDTFGSGAVDDDWQEAH---ERLAELEEKLPVAVNEQTGNGERDEMDLLGDHEE 84
+I + D+ F GA+ +D + + E + EL+E++ + + E+ + E + M + + E+
Sbjct: 373 QIQAYLDNIFDVGALLEDTETKNAVLEHMEELQEQVAL-LTERLRDAENESMAKIAELEK 431
Query: 85 NLAERLSKMVIENELEDPAIMRAVQTRPVLQPQPGSLNSSIWDGSEVLRRIRGPLLAQEM 144
L++ ++ E + RP P+P + L L +E+
Sbjct: 432 QLSQARKELETLRERFSESTAMGASRRP---PEPEKAPPAAPTRPSALE-----LKVEEL 483
Query: 145 PTVSVLEYALPQRPPQGPEDDRDLSERALPRRSTSPIIGSPPVRAVPIGTPPKQMAVPSF 204
++ R +GP D +S LP +P G P VP G+P +A +
Sbjct: 484 EEKGLI------RILRGPGDA--VSIEILPVAVATPSGGDAPTPGVPTGSPSPDLAPAAE 535
Query: 205 TQQILCPKPVHVRPPMPPRYPAPYGERMSPNQLCSVPNSSLLGHPFPPSVPPVLSPLQRA 264
P P PP PP P SP + PPS PP PL
Sbjct: 536 ------PAPGAAPPPPPPLPGLP-----SPQEA-------------PPSAPPQAPPL--- 568
Query: 265 QLLGGAQLQPGRMSPSQFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPS 324
PG P +PG + P PP PG PP
Sbjct: 569 ---------PGSPEPPPAPPLPGDLPPPPPPP-------------PPPPGTDGPVPPPPP 606
Query: 325 ATPPPQQHPP 334
PPP PP
Sbjct: 607 PPPPPPGGPP 616
>gi|13699803 WAS protein family, member 3 [Homo sapiens]
Length = 502
Score = 50.1 bits (118), Expect = 8e-06
Identities = 59/206 (28%), Positives = 72/206 (34%), Gaps = 44/206 (21%)
Query: 164 DDRDLSERALPRRSTSPIIGSPPVRA--VPIGTPPKQMAVPSF------TQQILCPKPVH 215
D D S A P S P +P A VP P Q A + + + +P
Sbjct: 244 DVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQ 303
Query: 216 VRPPMPPRYP---------APYGERMSPNQLCSVPNSSLLGHPFPPSVPPVLSPLQRAQL 266
PP PP+ P AP M P Q+ N S P PP PPV+ Q A +
Sbjct: 304 PPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPS---GPPPPPPPPVIPSAQTAFV 360
Query: 267 LGGAQLQPGRMSPSQFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPSAT 326
SP Q P F S + PP+ G + PP
Sbjct: 361 -----------SPLQMPMQPPFPASASST--------HAAPPHPPSTGLLVT-APPPPGP 400
Query: 327 PPPQQHPPGPGPHLQNLRSQAPMFRP 352
PPP PPGPG L S +PM P
Sbjct: 401 PPPPPGPPGPGSSL----SSSPMHGP 422
>gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]
Length = 1303
Score = 50.1 bits (118), Expect = 8e-06
Identities = 60/216 (27%), Positives = 84/216 (38%), Gaps = 30/216 (13%)
Query: 146 TVSVLEYALPQRPPQGPEDDRDLSERALPRRSTSPIIGSPP-VRAVPIGT-PPKQMAVPS 203
T +L+ L G ED++++ E L ++ +P+ PP V +P PP A S
Sbjct: 474 TRELLDKMLADDAEAGAEDEKEVEE--LKKQGINPLPKPPPGVGLLPTPPRPPGPQAPTS 531
Query: 204 FTQQILC-----PKPVHVRPPMPPRYPAPYGERMSPNQLCSVPNSSLLGHPFPPSVPPVL 258
+ + P P PP PP+ P P E +SP QL + P V+
Sbjct: 532 PNGRPMQGGPPPPPPPPPPPPGPPQMPMPVHEPLSPQQL---QQQDMYNKKIPSLFEIVV 588
Query: 259 SPL-QRAQLLG----GAQLQPGRMSPSQFARVPGFVGSPL-----AAMNPKLLQGRVGQM 308
P Q A+ LG G PG M P PG +G P+ M+P + M
Sbjct: 589 RPTGQLAEKLGVRFPGPGGPPGPMGPGPNMGPPGPMGGPMHPDMHPDMHPDMHPDMHADM 648
Query: 309 ---LPPAPGFRAFFSAPPSAT--PPPQQHPPGPGPH 339
+P PG PP PP + PG PH
Sbjct: 649 HADMPMGPGMN---PGPPMGPGGPPMMPYGPGDSPH 681
Score = 31.2 bits (69), Expect = 3.8
Identities = 19/48 (39%), Positives = 24/48 (50%), Gaps = 5/48 (10%)
Query: 320 SAPPSATPPPQQHPPGPGPHLQNLRSQ---APMFRPDTTHLHPQHRRL 364
+AP + PPP + PP P P + S +P RP T HL H RL
Sbjct: 3 AAPGTPPPPPSESPPPPSPPPPSTPSPPPCSPDARPATPHL--LHHRL 48
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 49.7 bits (117), Expect = 1e-05
Identities = 47/184 (25%), Positives = 67/184 (36%), Gaps = 21/184 (11%)
Query: 176 RSTSPIIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVRPPMPPRYPAPYGERMSPN 235
+S P I PP VP PP P L P P P P++ AP P
Sbjct: 695 QSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPC---APSLPQFSAP----PPPL 747
Query: 236 QLCSVPNSSLLGHPFPPSVPPVLSPLQRAQLLGGAQLQPGRMSPSQFARVPGFVGSPLAA 295
++ V + + + P PP PP+ +PL P + P +P + A
Sbjct: 748 KIHQVQHITQVAPPTPPPPPPIPAPL------------PPQAPPKPLVTIPAPTSTKTVA 795
Query: 296 MNPKLLQGRVGQMLPPAPGFRAFFSAPPSATPPPQQHPPGPGPHLQNLRSQAPMFRPDTT 355
P + Q PP P + + P S PP PP P P + Q+ +P +
Sbjct: 796 --PVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPS 853
Query: 356 HLHP 359
L P
Sbjct: 854 PLSP 857
Score = 47.0 bits (110), Expect = 7e-05
Identities = 59/250 (23%), Positives = 83/250 (33%), Gaps = 46/250 (18%)
Query: 112 PVLQPQPGSLNSSIWDG--SEVLRRIRGPLLAQEMPTVSVLEYALPQRPPQGPEDDRDLS 169
P P PGS + + + L + P ++ V + P PP P L
Sbjct: 715 PPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLP 774
Query: 170 ERALPR-----------RSTSPII--GSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHV 216
+A P+ ++ +P++ +PP P+ KQ P+F P
Sbjct: 775 PQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQ---PAF--------PASY 823
Query: 217 RPPMPPRYPAPYGERMSPNQ--LCSVPNSSLLGHPFPPSV--------PPVLSPLQRAQL 266
PP PP P P P Q C+ P S L P P V PP P +Q
Sbjct: 824 IPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLS-PVPSVVKQIASQFPPPPTPPAMESQP 882
Query: 267 LGGAQLQPGRMSPSQFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPSAT 326
L SP P + S + +P PP P + PP +
Sbjct: 883 LKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDF---------PPPPPESSLVFPPPPPS 933
Query: 327 PPPQQHPPGP 336
P P PP P
Sbjct: 934 PVPAPPPPPP 943
Score = 42.0 bits (97), Expect = 0.002
Identities = 56/210 (26%), Positives = 75/210 (35%), Gaps = 36/210 (17%)
Query: 158 PPQGPEDDRDLSERALPRRSTSPIIGSPPVRAVPIGTPPKQMAV--------PSFTQQIL 209
PP P + LP++ S PP P+ + KQ+A P+ Q L
Sbjct: 825 PPSPPTPPVPVPPPTLPKQQ-SFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPL 883
Query: 210 CPKPVHVRPPMPPRYPA-PYGERMS-----PNQLCSVPNSSLLGHPFPPSV--------P 255
P P +V P PP A P + S P+ P SSL+ P PPS P
Sbjct: 884 KPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPP 943
Query: 256 PVLSPLQRAQLLGGAQLQ----PGRMSPSQFARVPGFVGSPLAAMNPK----LLQGRVGQ 307
P SP G + PG P + + S A +P+ + V +
Sbjct: 944 PTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSK 1003
Query: 308 MLPPAPGFRAFFSAPPSATPPPQQHPPGPG 337
PPA +P T PP PP PG
Sbjct: 1004 FTPPAES-----GSPSKETLPPPAAPPKPG 1028
Score = 37.7 bits (86), Expect = 0.041
Identities = 44/200 (22%), Positives = 69/200 (34%), Gaps = 23/200 (11%)
Query: 158 PPQGPEDDRDLSERALPRRSTSPIIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVR 217
PP P A+ + +P S P + P PP ++ Q+ P P
Sbjct: 710 PPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAP--PPPLKIHQVQHITQVAPPTP---- 763
Query: 218 PPMPPRYPAPYGERMSPNQLCSVPN-------SSLLGHPFPPSVPPVLSPLQRAQLLGGA 270
P PP PAP + P L ++P + ++ PP+ P + P ++ +
Sbjct: 764 -PPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPAS 822
Query: 271 QLQPGRMSPSQFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFFSA--PPSATPP 328
+ P +P P V P L P P ++ PP TPP
Sbjct: 823 YIPPSPPTP------PVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPP 876
Query: 329 PQQHPPGPGPHLQNLRSQAP 348
+ P P N+ Q+P
Sbjct: 877 AMESQP-LKPVPANVAPQSP 895
Score = 37.0 bits (84), Expect = 0.069
Identities = 54/187 (28%), Positives = 64/187 (34%), Gaps = 32/187 (17%)
Query: 185 PPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVRPPMPPRYPAPYGERMSPNQLCSVPNSS 244
P VP +P ++ P Q P P PP PP P P P+Q S P++
Sbjct: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQ--SAPSA- 657
Query: 245 LLGHPFPPSVP-PVLSPLQRAQLLGGAQLQPGRMSPSQFARV-------PGFVGSPLAAM 296
G P V ++ LQ A GA +P Q V P V P
Sbjct: 658 --GSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP 715
Query: 297 NPKLLQGRVGQMLPPAPGFRAF--FSAPPS-------------ATPPPQQHPPGPGPHLQ 341
P G L PAP + FSAPP A P P PP P P
Sbjct: 716 PPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAP--- 772
Query: 342 NLRSQAP 348
L QAP
Sbjct: 773 -LPPQAP 778
Score = 32.0 bits (71), Expect = 2.2
Identities = 52/231 (22%), Positives = 81/231 (35%), Gaps = 52/231 (22%)
Query: 138 PLLAQEMPTVSVLEYALPQRPPQGPEDDRDLSERALPRRSTSPIIGSPPVRAVPIGTPPK 197
P + P V PQ PP + +A P+ S I PV + PP
Sbjct: 875 PPAMESQPLKPVPANVAPQSPP---------AVKAKPKWQPSSI----PVPSPDFPPPPP 921
Query: 198 QMAVPSFTQQILCPKPVHVRPPMPPRYPAPYGERM--------------------SPNQL 237
+ ++ P PV PP PP +P ++ +P +
Sbjct: 922 ESSLVFPPPP---PSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRN 978
Query: 238 CSVPNSSLLGHPFP--PSVPPVL----------SPLQRAQLLGGAQLQPGRMSPSQFARV 285
S+ +SS HP P PSV ++ SP + A +PG+++ S +
Sbjct: 979 SSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSG-VNL 1037
Query: 286 PGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPSATPPPQQHPPGP 336
PG + + +L GR + P + PP PPP+ P P
Sbjct: 1038 PGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPP---PPPETELPLP 1085
Score = 30.8 bits (68), Expect = 5.0
Identities = 17/42 (40%), Positives = 18/42 (42%), Gaps = 5/42 (11%)
Query: 309 LPPAPGFRAFFSAPPSATPPPQQHPPGPGPHLQNLRSQAPMF 350
LPP P PP PPP PP P + S APMF
Sbjct: 628 LPPPPP-----PPPPPPPPPPPPPPPLPSQSAPSAGSAAPMF 664
>gi|7662302 TBK1 binding protein 1 [Homo sapiens]
Length = 615
Score = 49.3 bits (116), Expect = 1e-05
Identities = 81/305 (26%), Positives = 116/305 (38%), Gaps = 52/305 (17%)
Query: 38 GSGAVDDDWQEAHERLAELE-----EKLPVAVNEQTGNGERDEM-----DLLGDHEENLA 87
GSG W + +++LE E L A E G R+E + L + L
Sbjct: 206 GSGLSHAGWPGSTPSVSDLERRRLEEALEAAQGEARGAQLREEQLQAECERLQGELKQLQ 265
Query: 88 ERLSKMVIENELE-DPAIMRAVQTRPVLQPQPGSLNSSIWDGSEVLRRIRGPLLAQEMPT 146
E ++ + N+ E D A ++ V V +L + + +E L R+R E+ +
Sbjct: 266 ETRAQDLASNQSERDMAWVKRVGDDQV------NLALAYTELTEELGRLR------ELSS 313
Query: 147 VS--VLEYALPQRPPQGPEDDRDLSERALPR-RSTSPIIGSPPVRAVPIGTPPKQMAVPS 203
+ +L L ++ G + LS+R P + SP SPP RA P PP Q VP
Sbjct: 314 LQGRILRTLLQEQARSGGQRHSPLSQRHSPAPQCPSP---SPPARAAP-PCPPCQSPVPQ 369
Query: 204 FTQQIL-CPKPVHVRPPMPPRYPAPYGERMSPNQLCSVPNSSLLGHPFPPSV------PP 256
+ CP P R P P P+P +R SP S P PPS PP
Sbjct: 370 RRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPP 429
Query: 257 VLSPLQRAQLLGGAQLQP----------GRMSPSQFARVPGFVGSPLAAMNPKLLQGRVG 306
P L A +P GR S S+ A G+ A +P LQ
Sbjct: 430 PPPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAE-----GAAYAGASPPWLQAEAA 484
Query: 307 QMLPP 311
+ P
Sbjct: 485 TLPKP 489
Score = 34.7 bits (78), Expect = 0.34
Identities = 36/136 (26%), Positives = 51/136 (37%), Gaps = 22/136 (16%)
Query: 226 APYGERMSPNQLCSVPNSSLLGHPFPPSVPPVLSPLQRAQLLGGAQLQPGRMSPSQFARV 285
+P +R SP C P+ P PP SP+ P R SP
Sbjct: 335 SPLSQRHSPAPQCPSPSPPARA---APPCPPCQSPV------------PQRRSPVPPCPS 379
Query: 286 PGFVGSPLAAMNPKLLQGRVGQMLP----PAPGFRAFFSAPPSATPPPQQHPPGPGPHLQ 341
P SP + P + R + P P+P R+ PPS P PQ PP P P +
Sbjct: 380 PQQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRS--PVPPSC-PAPQPRPPPPPPPGE 436
Query: 342 NLRSQAPMFRPDTTHL 357
++ +P + H+
Sbjct: 437 RTLAERAYAKPPSHHV 452
>gi|57863314 vacuolar protein sorting 37C [Homo sapiens]
Length = 355
Score = 48.9 bits (115), Expect = 2e-05
Identities = 99/384 (25%), Positives = 139/384 (36%), Gaps = 92/384 (23%)
Query: 5 ESLEDCPLDEDEDAFQGLGEEDEEIDQFNDDTFGSGAVDDDWQEAHERLAELEEKLPVAV 64
E+L+D L E E+ L + E IDQ S V D +LE ++ +A
Sbjct: 2 ETLKDKTLQELEE----LQNDSEAIDQL---ALESPEVQD---------LQLEREMALAT 45
Query: 65 NEQTGNGERDEMDLLGDHEENLAERLSKM--VIENELEDPAIMRAVQTRPVLQPQPGSL- 121
N + L NL++R ++ ++E E A + + QPG+L
Sbjct: 46 NRSLAERNLEFQGPLEISRSNLSDRYQELRKLVERCQEQKAKLEKFSSAL----QPGTLL 101
Query: 122 ------NSSIWDGSEVLRRIRGPLLAQEMPTVSVLEYALPQRPPQGPEDDR--DLSERAL 173
I + SE + L E+P + LE R R L E
Sbjct: 102 DLLQVEGMKIEEESEAMAE---KFLEGEVPLETFLENFSSMRMLSHLRRVRVEKLQEVVR 158
Query: 174 PRRSTSPIIGS-------PPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVRPPMP-PRYP 225
R++ + G PPVR VP GTPP P +PP+ P YP
Sbjct: 159 KPRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQP--------------QPPLAMPPYP 204
Query: 226 APYGERMSPNQLCSVPNSSLLGHPFPPSVPPVLS----------PLQRAQLLG-----GA 270
PY SP+ S+P PP+ PV+S P A LG G
Sbjct: 205 LPY----SPSP--SLPVGPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGY 258
Query: 271 QLQPGRMSPSQFARVPGFVGSPLAAMNP--KLLQGRVGQMLPPAPGFRAFFSAPPSATPP 328
P R P + PG+ G+P+ A P L GR P+PG+ P + P
Sbjct: 259 SWSPQRSMPPR----PGYPGTPMGASGPGYPLRGGRA-----PSPGYPQQSPYPATGGKP 309
Query: 329 P----QQHPPGPGPHLQNLRSQAP 348
P Q P PG ++ Q P
Sbjct: 310 PYPIQPQLPSFPGQPQPSVPLQPP 333
>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
Length = 701
Score = 48.9 bits (115), Expect = 2e-05
Identities = 53/228 (23%), Positives = 87/228 (38%), Gaps = 20/228 (8%)
Query: 118 PGSLN---SSIWDGSEVLRRIRGPLLAQEMPTVSVLEYALPQRPPQGPED---------- 164
PG +N S ++ + + L ++E+P+ +V A P P
Sbjct: 470 PGDINFNVSGLFSAVTLQDTVSDRLASEELPSTAVPTPATTPAPAPAPAPAPAPALASAA 529
Query: 165 DRDLSERALPRRSTSP-IIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVRPPMPPR 223
++ +E +P R SP + SPP A P+ ++ P+ + + P V PP
Sbjct: 530 TKERTESEVPPRPASPKVTRSPPETAAPVEDMARRTKRPAPARPTMPPPQVSGSRSSPPA 589
Query: 224 YPAPYGERMSPNQLCSVPNSSLLGHPFPPSVPPVLSPLQRAQLLGGAQLQPGRMSPSQFA 283
P P G SP ++P + P+VPP L P ++ P SP+
Sbjct: 590 PPLPPGSG-SPGTPQALPRRLVGSSLRAPTVPPPLPPTPPQPARRQSRRSPASPSPAS-- 646
Query: 284 RVPGFVG-SPLAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPSATPPPQ 330
PG SP++ NP + AP + PP+ P P+
Sbjct: 647 --PGPASPSPVSLSNPAQVDLGAATAEGGAPEAISGVPTPPAIPPQPR 692
Score = 33.5 bits (75), Expect = 0.77
Identities = 35/135 (25%), Positives = 51/135 (37%), Gaps = 5/135 (3%)
Query: 130 EVLRRIRGPLLAQE-MPTVSVL-EYALPQRPPQGPEDDRDLSERALPRRSTSPIIGSPPV 187
++ RR + P A+ MP V + P PP P + +ALPRR + +P V
Sbjct: 560 DMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTV 619
Query: 188 RAVPIGTPPKQMAVPSFTQQILCPKPVHVRP--PMPPRYPAPYGERMSPNQLCSVPNSSL 245
P+ P Q A + P P P P P P + ++
Sbjct: 620 PP-PLPPTPPQPARRQSRRSPASPSPASPGPASPSPVSLSNPAQVDLGAATAEGGAPEAI 678
Query: 246 LGHPFPPSVPPVLSP 260
G P PP++PP P
Sbjct: 679 SGVPTPPAIPPQPRP 693
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 48.5 bits (114), Expect = 2e-05
Identities = 78/329 (23%), Positives = 106/329 (32%), Gaps = 75/329 (22%)
Query: 43 DDDWQEAHERLAELEEKLPVAVNEQTGNGERDEMDLLGDHEENLAERLSKMVIENEL--E 100
D+D EA L + + L + E NG+ L+G E +++L ++ + EL +
Sbjct: 94 DEDLTEAVHSLG-VNDILEIKFFENRANGQSKGFALVGVGSEASSKKLMDLLPKRELHGQ 152
Query: 101 DPAIMRA---------VQTRPVLQ-----------PQPGSLNSSIWDGSEVLRRIRGPLL 140
+P + +Q+R Q P GS ++ G R G +
Sbjct: 153 NPVVTPCNKQFLSQFEMQSRKTTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVP 212
Query: 141 AQEM---------PTVSVLEYALPQRPPQGPEDDRDLSERALPRRSTSPIIGSPPVRAVP 191
+ P P RPP GP P + P + PP R
Sbjct: 213 GGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRG-- 270
Query: 192 IGTPPKQMAVPS--FTQQILCPKPVHVRPPMPPRYPAPYGERMSPNQLCSVPNSSLLGHP 249
PP + P F Q L P P PP+P P P G P
Sbjct: 271 -DRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPP-------------------GPP 310
Query: 250 FPPSVPPVLSPLQRAQLLGGAQLQPGRMSPSQFARVPGFVGSPLAAMNPKLLQGRVGQML 309
P PP PG P R PG +G PL P L G
Sbjct: 311 PPQQGPPP---------------PPGPFPP----RPPGPLGPPLTLAPPPHLPGPPPGAP 351
Query: 310 PPAPGFRAFFSAPPSATPPPQQHPPGPGP 338
PPAP F PP+ + P GP P
Sbjct: 352 PPAPHVNPAFFPPPTNSGMPTSDSRGPPP 380
Score = 38.9 bits (89), Expect = 0.018
Identities = 52/168 (30%), Positives = 60/168 (35%), Gaps = 28/168 (16%)
Query: 193 GTPPKQMAVPSFTQQILCPKPVHVRPPMPPRYPAPYGE-RMSPNQLCSVPNSSLLGHPFP 251
G PP P F P+P + PP PP P P ++ P L PN P
Sbjct: 224 GGPP-----PPFPAGQTPPRPP-LGPPGPPGPPGPPPPGQVLPPPLAGPPNRG----DRP 273
Query: 252 PSVPPVLSPLQRAQLLGGAQLQPGRMSPSQFARVPGF---VGSPLAAMNPKLLQGRVGQM 308
P PPVL P Q G L P + P VPG+ G P P G
Sbjct: 274 P--PPVLFP---GQPFGQPPLGP--LPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPR 326
Query: 309 LPPAPGFRAFFSAPPSATPPPQQHPPGPGPHLQNLRSQAPMFRPDTTH 356
PP P APP P P P P PH+ P F P T+
Sbjct: 327 -PPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVN------PAFFPPPTN 367
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 48.1 bits (113), Expect = 3e-05
Identities = 88/349 (25%), Positives = 124/349 (35%), Gaps = 61/349 (17%)
Query: 112 PVLQPQPGSLNSSIWDGSEVLRRIRGPLLAQEMPTVSVLEYALPQRPPQGPEDDRDLSER 171
PVL+PQ L S++D P+ P + + + LP PQ PE
Sbjct: 806 PVLEPQ---LPGSVFD----------PIGHFTQPILHLPQPELPPHLPQPPE-------H 845
Query: 172 ALPRRSTSPIIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVRPPMPPRYPAPYGER 231
+ P + SPP + P+Q + PS L PKP RPP PA
Sbjct: 846 STPPHLNQHAVVSPPALHNAL---PQQPSRPSNRAAALPPKPA--RPPAVS--PALTQTP 898
Query: 232 MSPNQLCSVPNSSLLGHPFPPSVPPVLSPLQRAQLLGGAQLQPGRMSPSQFARVPGFVGS 291
+ P + P LL PP+ PP+ S + L ++QP P+
Sbjct: 899 LLPQPPMAQPPQVLLEDEEPPA-PPLTSMQMQLYLQQLQKVQP----PTPLLPSVKVQSQ 953
Query: 292 PLAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPSATPPP-------QQHPPGPGP-HLQNL 343
P + P PP P + P PPP QQH P P P HLQ +
Sbjct: 954 PPPPLPP-----------PPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPM 1002
Query: 344 RSQAPMFRPDTTHLHPQHRRLLHQRQQQNRSQHRNLNGAGDRGSHRSSHQDHLRKDPYAN 403
+ + +P PQ ++ H Q + H S H + DPY+
Sbjct: 1003 QFSTHIQQPPP----PQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPR--HHKSDPYST 1056
Query: 404 LMLQREKD--WVSKIQMMQLQSTDPYLDDFYYQNYFEKLEKLSAAEEIQ 450
L+ + QM Q QS QN K ++L AA +Q
Sbjct: 1057 GHLREAPSPLMIHSPQMSQFQSLTHQSPP--QQNVQPKKQELRAASVVQ 1103
Score = 38.5 bits (88), Expect = 0.024
Identities = 38/140 (27%), Positives = 50/140 (35%), Gaps = 21/140 (15%)
Query: 211 PKPVHVRPPMPPRYPAPYGERMSPNQLCSVPNSSLLGHPFPPSVPPVLSPLQRAQLLGGA 270
P PV +PP PP+ P P P Q P P PPS+P +P ++
Sbjct: 750 PAPVPQQPPPPPQQPPP---PPPPQQQQQPPPP-----PPPPSMPQQAAPAMKSSPPPFI 801
Query: 271 QLQPGRMSPSQFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPSATPPP- 329
Q + P ++PG V P+ +L P P PP + PP
Sbjct: 802 ATQVPVLEP----QLPGSVFDPIGHFTQPILH-------LPQPELPPHLPQPPEHSTPPH 850
Query: 330 -QQHPPGPGPHLQNLRSQAP 348
QH P L N Q P
Sbjct: 851 LNQHAVVSPPALHNALPQQP 870
Score = 34.7 bits (78), Expect = 0.34
Identities = 48/193 (24%), Positives = 67/193 (34%), Gaps = 46/193 (23%)
Query: 175 RRSTSPIIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVRPPMPPRYPAPYGERMSP 234
+++ +P+ PP PP Q P P P + P PP P ++ +P
Sbjct: 747 QQAPAPVPQQPP--------PPPQQPPPP-------PPPQQQQQPPPPPPPPSMPQQAAP 791
Query: 235 NQLCSVPNSSLLGHPFPPSVPPVLSP-------------LQRAQLLGGAQLQPGRMSPSQ 281
S P PF + PVL P Q L +L P P +
Sbjct: 792 AMKSSPP-------PFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPE 844
Query: 282 FARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPSATPPPQQHPPGPGPHLQ 341
+ P + A ++P L + Q P P RA +A PP PP P L
Sbjct: 845 HSTPPHL--NQHAVVSPPALHNALPQQ-PSRPSNRA------AALPPKPARPPAVSPALT 895
Query: 342 N--LRSQAPMFRP 352
L Q PM +P
Sbjct: 896 QTPLLPQPPMAQP 908
Score = 33.5 bits (75), Expect = 0.77
Identities = 20/80 (25%), Positives = 38/80 (47%), Gaps = 7/80 (8%)
Query: 169 SERALPRRSTSPIIGSPPVRAVPIGTPP--KQMAVPSFTQQILCPKPVHVRPPMPPR--- 223
++ + P ++ +P PPV+A P P + V + ++ P+P+ PP+PP+
Sbjct: 200 TQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQP 259
Query: 224 --YPAPYGERMSPNQLCSVP 241
PAP + P + + P
Sbjct: 260 PPAPAPQPVQSHPPIIAATP 279
Score = 30.4 bits (67), Expect = 6.5
Identities = 37/142 (26%), Positives = 65/142 (45%), Gaps = 11/142 (7%)
Query: 30 DQFNDDTFGS-GAVDDDWQEAHERLAELEEKLPVAVNEQTGNGERDEMDLLGDHEENLAE 88
D +D + S + DD +E +RLAEL+E+L AV+EQ + + + E++ E
Sbjct: 487 DSSSDSSSDSDSSTDDSEEERAQRLAELQEQLK-AVHEQLAALSQPQQNKPKKKEKDKKE 545
Query: 89 -RLSKMVIENELEDPAIMRAVQTRPVLQPQPGSLNSSIWDGSEVLRRIRGPLLAQEMPTV 147
+ K + E+E+ +A + P + S NS+ V ++ P+ ++ PT
Sbjct: 546 KKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSN------VSKKEPAPMKSKPPPTY 599
Query: 148 SVLEYALPQRPPQGPEDDRDLS 169
E + P E+ R LS
Sbjct: 600 ESEEE--DKCKPMSYEEKRQLS 619
>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
Length = 1170
Score = 48.1 bits (113), Expect = 3e-05
Identities = 79/294 (26%), Positives = 107/294 (36%), Gaps = 65/294 (22%)
Query: 98 ELEDPAIMRAVQTRPVLQPQPGSLNSSIWDGSEVLRRIRGPLL---AQEMPTVSVLEYAL 154
+LE P +M + PV QP +++ + V+ ++ PLL +Q P V
Sbjct: 364 QLETPRMM--MTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVG------ 415
Query: 155 PQRPPQGPEDDRDLSERALPRRSTSPIIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPV 214
PQR P PE P+ + P+ S F+Q P
Sbjct: 416 PQRFPGPPE---------FPQHTPGPVPNS-------------------FSQPPRLPLQD 447
Query: 215 HVRPPMPPRYPAPY-----GERMSPNQLCSVPNSSLLGHPFPPSVPPVLSPLQRAQLLGG 269
R P PP+ P+ GE P+ L S P PP PP L L
Sbjct: 448 QWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRS-----PPPPPPPPTL--------LNS 494
Query: 270 AQLQPGRMSPSQFARV-PGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPSAT-- 326
+ P + SP F + P F + P+ R + PP P FS P SAT
Sbjct: 495 SHPVPTQ-SPLPFTQPGPAFNQQGQQPVFPRERPVRPA-LQPPGPVGILHFSQPGSATTR 552
Query: 327 ---PPPQQHPPGPGPHLQNLRSQAPMFRPDTTHLHPQHRRLLHQRQQQNRSQHR 377
PP Q PGPG +Q + P L P H+ Q QQQ QH+
Sbjct: 553 PFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQ 606
Score = 30.8 bits (68), Expect = 5.0
Identities = 63/246 (25%), Positives = 84/246 (34%), Gaps = 39/246 (15%)
Query: 100 EDPAIMRAVQTRPVLQPQ-PGSLNSSIWDGSEVLRRI---RGPLLAQE----MPTVSVLE 151
+ P R RP LQP P + GS R R P L +PT +
Sbjct: 518 QQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPN 577
Query: 152 YALPQRPPQGPEDDRDLSERALPRRSTSPIIGSPPVRAVPIGTPPKQMAVPSFTQQILCP 211
P PP P + P++ PP + P PP Q P
Sbjct: 578 LQGPLHPPLPPPHQPQPQQ---PQQQ-------PPPQHQPPHQPPHQ------------P 615
Query: 212 KPVHVRPPM-PPRYPAPYGERMSPNQLCSVPNSSLLGHPFPPSVPPVLSPLQRAQ-LLGG 269
P H PP PP++P P + + SVP L+ P S P +Q AQ
Sbjct: 616 PPQHQPPPQHPPQHP-PQHQHHHHHHHLSVPPPPLM----PMSQPQFRPHVQTAQPQASS 670
Query: 270 AQLQ-PGRMSPSQFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFFSAPP-SATP 327
+++Q P R P+ M P + + LP AP S+ SATP
Sbjct: 671 SRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVIEMSSSRCSATP 730
Query: 328 PPQQHP 333
Q P
Sbjct: 731 SAQVKP 736
>gi|166064029 angiomotin isoform 1 [Homo sapiens]
Length = 1084
Score = 48.1 bits (113), Expect = 3e-05
Identities = 102/439 (23%), Positives = 151/439 (34%), Gaps = 83/439 (18%)
Query: 166 RDLSERALPRR-STSPIIGSPPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVRPPMPPRY 224
R LSER + +TS + PPV + P+ P + T K + P+P ++
Sbjct: 172 RSLSERLMQMSLATSGVKAHPPVTSAPLSPPQPNDLYKNPTSSSEFYK---AQGPLPNQH 228
Query: 225 PAPYGERMSPNQLCSVPNSSLLGHPFPPSVPPVLSPLQRAQLLGGAQL-QPGRMS----- 278
E P P G P P SV V P + +L QPGR
Sbjct: 229 SLKGMEHRGPP-----PEYPFKGMP-PQSV--VCKPQEPGHFYSEHRLNQPGRTEGQLMR 280
Query: 279 ---PSQF--ARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPSATPPPQQHP 333
P ++ AR + PL+A N Q + G +PPS P +HP
Sbjct: 281 YQHPPEYGAARPAQDISLPLSARNS---QPHSPTSSLTSGGSLPLLQSPPSTRLSPARHP 337
Query: 334 --PGPGPHLQNLRSQAPMFRPDTTHL---------------------HPQHRRLLHQRQQ 370
P G H +L F P+ H H H Q+QQ
Sbjct: 338 LVPNQGDHSAHLPRPQQHFLPNQAHQGDHYRLSQPGLSQQQQQQQQQHHHHHHHQQQQQQ 397
Query: 371 QNRSQHRNLNGAGDRGSHRSSHQDHLRKDPYANLMLQREKDWVSKIQMMQLQSTDPYLDD 430
Q + Q A R S+ + DP+A VS+ Q M +D
Sbjct: 398 QPQQQPGEAYSAMPRAQPSSASYQPVPADPFA---------IVSRAQQMVEILSD----- 443
Query: 431 FYYQNYFEKLEKLSAAEEIQGDGPKKERTKLITPQVAKLEHAYKPVQFEGSLGKLTVSSV 490
E + +E++G K R + + ++ ++ AY+ + S + ++
Sbjct: 444 ----------ENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREALEKAM 493
Query: 491 NNP-----RKMIDAVVTSRSEDDETKEKQVRDKRRKTLVIIEKTYSLLLDVEDYERRYLL 545
N R+M D R E ET KQ+ +K + KT S L +R
Sbjct: 494 RNKLEGEIRRMHDFNRDLR-ERLETANKQLAEKEYEGSEDTRKTISQLFAKNKESQREKE 552
Query: 546 SLEEE----RPALMDDRKH 560
LE E R D R+H
Sbjct: 553 KLEAELATARSTNEDQRRH 571
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 48.1 bits (113), Expect = 3e-05
Identities = 74/360 (20%), Positives = 124/360 (34%), Gaps = 49/360 (13%)
Query: 15 DEDAFQGLGEEDEEIDQFNDDTFGSGAVDDDWQEAHERLAELEEKLPVAVNEQTGNGERD 74
+ED + L EE E ++ + DDD ++ +R + A++E + E+D
Sbjct: 1034 EEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEAS---EKD 1090
Query: 75 EMDLLGDHEENLAERLSKMVIENELEDPAIMRAVQTRPVLQPQPGSLNSSIWDGSEVLRR 134
E D D EE ++ SK + E + S SS D EV+ R
Sbjct: 1091 EGD--SDEEETVSIVTSKAEATSSSES-------SESSEFESSSESSPSSSEDEEEVVAR 1141
Query: 135 ------------------IRGPLLAQEMPTVSVLEYALPQRPPQGPEDDRDLSERALPRR 176
GP ++ + L P G E++ D+ A+
Sbjct: 1142 EEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPE 1201
Query: 177 STSPIIGSPPVRAVPIGT--------PPKQMAVPSFTQQILCPKP----VHVRPPMPPRY 224
++ PP +P+G PP++ + +L P+P V RPP+ P
Sbjct: 1202 ERPSMLDEPP---LPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPER 1258
Query: 225 PAPYGERMSPN--QLCSVPNSSLLGHPFPPSVPPVLSPLQRAQLLGGAQLQPGRMSPSQF 282
+ + P + +P L P PP PP P + P ++
Sbjct: 1259 APEHDLEVEPEPPMMLPLPLQPPLPPPRPPR-PPSPPPEPETTDASHPSVPPEPLAEDHP 1317
Query: 283 ARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPGFRAFFSAPPSATPPPQQHPPGPGPHLQN 342
PG GS + + + + G P + G + P P + P P P L +
Sbjct: 1318 PHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSY-PAPSPSLSS 1376
Score = 42.0 bits (97), Expect = 0.002
Identities = 77/356 (21%), Positives = 114/356 (32%), Gaps = 67/356 (18%)
Query: 5 ESLEDCPLDEDEDAFQGLGEEDEEIDQFNDDTFGSGAVDDDWQEAHERLAELEEKLPVAV 64
ES DE+E + EE+EE + +++ S +D Q+ E A L P
Sbjct: 1126 ESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEE--AALAPGAPAV- 1182
Query: 65 NEQTGNGERDEMDLLGDHEENLAERLSKMVIENELEDPAIMRAVQTRPVLQPQPGSLNSS 124
+ G E +++ E L + + +E+PA R P L +
Sbjct: 1183 -DSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQE------- 1234
Query: 125 IWDGSEVLRRIRGPLLAQEMPTVSVLEYALPQRPPQGPEDDRDLSERALPRRSTSPIIGS 184
G +L P +E P P + PE D ++
Sbjct: 1235 ------------GAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPE------------- 1269
Query: 185 PPVRAVPIGTPPKQMAVPSFTQQILCPKPVHVRPPMPPRYPAPYGERMSPNQLCSVPNSS 244
PP + +P + P P PP PPR P+P E + +
Sbjct: 1270 ----------PPMMLPLP-----LQPPLP----PPRPPRPPSPPPEPETTDASHPSVPPE 1310
Query: 245 LLGHPFPPSVPPVLSPLQRAQLLGGAQLQPGRMSP------SQFARVPGFVGSPLA--AM 296
L PP P + L ++Q PG P P GSP + A
Sbjct: 1311 PLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAP 1370
Query: 297 NPKLLQGRVGQMLPPAPGFRAFFSAPPSATPPPQQHPPGPGPHLQNLRSQAPMFRP 352
+P L G LP PG F+ S P P P P + P+ P
Sbjct: 1371 SPSLSSGG----LPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASP 1422
Score = 37.4 bits (85), Expect = 0.053
Identities = 70/300 (23%), Positives = 105/300 (35%), Gaps = 67/300 (22%)
Query: 88 ERLSKMVIENELEDPAIMRAVQTRPVLQPQPGSLNSSIWDGSEVLRRIRGPLLAQEMPTV 147
E +S + + ED + + RP +P P + +EV L+ PT
Sbjct: 570 EDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVAL----DLVGDRTPTS 625
Query: 148 SVLEYALPQRPPQGPEDDRDLSERALPRRSTS------PIIGSPPVRAV----------- 190
++ Q +D ++S+ +P + P++ +P AV
Sbjct: 626 EKMDEG-----QQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLP 680
Query: 191 ---PIGTPPKQMAVPSFTQQILCPKPVHVRPPMPPRYPAPYGERMSPNQLCS---VPNSS 244
P G PP P Q P P + PP PP PA + P L + VP
Sbjct: 681 LPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPP 740
Query: 245 LLG--HPFPPSVPPVLSPLQRAQLLGG------------AQLQPGRMSPSQFARVPGFVG 290
+L PFPP + PV+ + + +LGG Q+ M+ P F+
Sbjct: 741 ILPPLPPFPPGLFPVMQ-VDMSHVLGGQWGGMPMSFQMQTQVLSRLMTGQGACPYPPFMA 799
Query: 291 SPLAAMNPKLL-----------------QGRVGQMLPPAPGFRAFFSAPPSATPPPQQHP 333
+ AA + L GR GQ PP P F S PP P Q+ P
Sbjct: 800 AAAAAASAGLQFVNLPPYRGPFSLSNSGPGR-GQHWPPLPKFDP--SVPPPGYMPRQEDP 856
Score = 30.0 bits (66), Expect = 8.5
Identities = 57/229 (24%), Positives = 74/229 (32%), Gaps = 45/229 (19%)
Query: 138 PLLAQEMPTVSVLEYALPQRPPQGPEDDRDLSERALPRR-----STSPIIGSP------P 186
P L+ +S+ +P P P LS LPR S +P P P
Sbjct: 1344 PPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLP 1403
Query: 187 VRAVPIGTPPKQ---MAVPSFTQQILCPKPVHVRPPMPPRYPAPYGERMSPNQLCSVPNS 243
V +P G ++ +A P + L P P+ + P+P PA + P
Sbjct: 1404 VCPLPTGRRDERSGPLASPVLLETGL-PLPLPLPLPLPLALPAV----LRAQARAPTPLP 1458
Query: 244 SLLGHPFPPSVPPVLSPLQRAQLLGGAQLQPGRMSPSQFARVPGFVGSPLAAMNPKLLQG 303
LL P PP+ R P R PS + V P A + L
Sbjct: 1459 PLLPAPLASCPPPMKRKPGR----------PRRSPPSMLSLDGPLVRPPAGAALGRELLL 1508
Query: 304 RVGQMLPPAPGF--------------RAFFSAPPSATPPPQQHPPGPGP 338
GQ P P F A APP PP PP P P
Sbjct: 1509 LPGQ--PQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPP 1555
>gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo
sapiens]
Length = 1235
Score = 47.8 bits (112), Expect = 4e-05
Identities = 66/264 (25%), Positives = 94/264 (35%), Gaps = 49/264 (18%)
Query: 138 PLLAQEMPTVSVLEYALPQRPPQ--GPEDDRDLSERALPRRSTSPIIGSPPVRAVPIGTP 195
P +AQ +P PQ PQ P D DL +R T PP+ P P
Sbjct: 300 PQVAQPIPQ--------PQTEPQLRAPSPDPDLVQR------TEAPPQPPPLSTQPPQGP 345
Query: 196 PKQMAVPSFTQQILCPKPVHVRPPMPPRYPAPYGERMSPNQLCSVPNSSLLGHPFPP--S 253
P+ P+ P+P RPP P + + P Q + P++ L P S
Sbjct: 346 PEAQLQPA-------PQPQVQRPPRPQSPTQLLHQNLPPVQ--AHPSAQSLSQPLSAYNS 396
Query: 254 VPPVLSPLQRAQLLGGAQLQPGRMSPSQFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAP 313
L+ L ++ A+ QP +P + P PL+ N L + PPA
Sbjct: 397 SSLSLNSLSSSRSSTPAKTQP---APPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAH 453
Query: 314 GFRAFFSAPPSATPPPQQ----------HPPGPGPHLQNLRSQ---------APMFRPDT 354
APP+A PPP HP G Q++ Q R +
Sbjct: 454 SHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGAS 513
Query: 355 THLHPQHRRLLHQRQQQNRSQHRN 378
P R HQ Q Q++ H++
Sbjct: 514 LGPPPYLRTEFHQHQHQHQHTHQH 537
>gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo
sapiens]
Length = 1259
Score = 47.8 bits (112), Expect = 4e-05
Identities = 66/264 (25%), Positives = 94/264 (35%), Gaps = 49/264 (18%)
Query: 138 PLLAQEMPTVSVLEYALPQRPPQ--GPEDDRDLSERALPRRSTSPIIGSPPVRAVPIGTP 195
P +AQ +P PQ PQ P D DL +R T PP+ P P
Sbjct: 300 PQVAQPIPQ--------PQTEPQLRAPSPDPDLVQR------TEAPPQPPPLSTQPPQGP 345
Query: 196 PKQMAVPSFTQQILCPKPVHVRPPMPPRYPAPYGERMSPNQLCSVPNSSLLGHPFPP--S 253
P+ P+ P+P RPP P + + P Q + P++ L P S
Sbjct: 346 PEAQLQPA-------PQPQVQRPPRPQSPTQLLHQNLPPVQ--AHPSAQSLSQPLSAYNS 396
Query: 254 VPPVLSPLQRAQLLGGAQLQPGRMSPSQFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAP 313
L+ L ++ A+ QP +P + P PL+ N L + PPA
Sbjct: 397 SSLSLNSLSSSRSSTPAKTQP---APPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAH 453
Query: 314 GFRAFFSAPPSATPPPQQ----------HPPGPGPHLQNLRSQ---------APMFRPDT 354
APP+A PPP HP G Q++ Q R +
Sbjct: 454 SHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGAS 513
Query: 355 THLHPQHRRLLHQRQQQNRSQHRN 378
P R HQ Q Q++ H++
Sbjct: 514 LGPPPYLRTEFHQHQHQHQHTHQH 537
>gi|30794372 polybromo 1 isoform 1 [Homo sapiens]
Length = 1602
Score = 47.8 bits (112), Expect = 4e-05
Identities = 40/124 (32%), Positives = 55/124 (44%), Gaps = 14/124 (11%)
Query: 250 FPPSVPPVLSPLQRAQLLGGAQ-LQPGRMSPSQFAR-VPGFVGSPLAAMNPKLLQGRVGQ 307
+PP +PP+ P+ +G Q L PG P VPG G P + + QG
Sbjct: 1403 YPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGV---MNQGVAPM 1459
Query: 308 MLPPAPGFRAFFSAPPSATPPPQQHPPG-PGPHLQNLRSQAPMFRPDTTHLH----PQHR 362
+ PAPG + PP QQ PP PGPH + P+ + TT + P+ +
Sbjct: 1460 VGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPH----PAGPPVIQQPTTPMFVAPPPKTQ 1515
Query: 363 RLLH 366
RLLH
Sbjct: 1516 RLLH 1519
>gi|93102371 polybromo 1 isoform 2 [Homo sapiens]
Length = 1582
Score = 47.8 bits (112), Expect = 4e-05
Identities = 40/124 (32%), Positives = 55/124 (44%), Gaps = 14/124 (11%)
Query: 250 FPPSVPPVLSPLQRAQLLGGAQ-LQPGRMSPSQFAR-VPGFVGSPLAAMNPKLLQGRVGQ 307
+PP +PP+ P+ +G Q L PG P VPG G P + + QG
Sbjct: 1383 YPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGV---MNQGVAPM 1439
Query: 308 MLPPAPGFRAFFSAPPSATPPPQQHPPG-PGPHLQNLRSQAPMFRPDTTHLH----PQHR 362
+ PAPG + PP QQ PP PGPH + P+ + TT + P+ +
Sbjct: 1440 VGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPH----PAGPPVIQQPTTPMFVAPPPKTQ 1495
Query: 363 RLLH 366
RLLH
Sbjct: 1496 RLLH 1499
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,855,034
Number of Sequences: 37866
Number of extensions: 2048897
Number of successful extensions: 15257
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 718
Number of HSP's that attempted gapping in prelim test: 11508
Number of HSP's gapped (non-prelim): 3192
length of query: 770
length of database: 18,247,518
effective HSP length: 110
effective length of query: 660
effective length of database: 14,082,258
effective search space: 9294290280
effective search space used: 9294290280
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.