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Search of human proteins with 189217853
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|189217853 matrix metalloproteinase 2 isoform b [Homo
sapiens]
(610 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens] 1317 0.0
gi|11342666 matrix metalloproteinase 2 isoform a preproprotein [... 1315 0.0
gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens] 601 e-172
gi|4505209 matrix metalloproteinase 13 preproprotein [Homo sapiens] 223 4e-58
gi|4505217 matrix metalloproteinase 3 preproprotein [Homo sapiens] 219 8e-57
gi|225543094 matrix metalloproteinase 1 isoform 2 [Homo sapiens] 218 2e-56
gi|4505215 matrix metalloproteinase 1 isoform 1 preproprotein [H... 218 2e-56
gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein ... 216 5e-56
gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens] 216 5e-56
gi|4505205 matrix metalloproteinase 10 preproprotein [Homo sapiens] 216 6e-56
gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens] 212 9e-55
gi|4505211 matrix metalloproteinase 15 preproprotein [Homo sapiens] 204 3e-52
gi|4826834 matrix metalloproteinase 14 preproprotein [Homo sapiens] 199 8e-51
gi|73858572 matrix metalloproteinase 12 preproprotein [Homo sapi... 191 2e-48
gi|4505219 matrix metalloproteinase 7 preproprotein [Homo sapiens] 189 5e-48
gi|11968059 matrix metalloproteinase 25 preproprotein [Homo sapi... 188 1e-47
gi|45359865 matrix metalloproteinase 20 preproprotein [Homo sapi... 187 2e-47
gi|112382270 matrix metalloproteinase 17 preproprotein [Homo sap... 181 2e-45
gi|73808268 matrix metalloproteinase 27 [Homo sapiens] 174 2e-43
gi|58331148 matrix metalloproteinase 11 preproprotein [Homo sapi... 170 4e-42
gi|4505213 matrix metalloproteinase 19 isoform rasi-1 preproprot... 151 2e-36
gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens] 146 6e-35
gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens] 146 6e-35
gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens] 146 6e-35
gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens] 146 6e-35
gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens] 146 6e-35
gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens] 146 6e-35
gi|47132547 fibronectin 1 isoform 7 preproprotein [Homo sapiens] 146 6e-35
gi|149999365 matrix metalloproteinase 16 isoform 2 preproprotein... 137 4e-32
gi|73808266 matrix metalloproteinase 26 preproprotein [Homo sapi... 132 1e-30
>gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]
Length = 610
Score = 1317 bits (3408), Expect = 0.0
Identities = 610/610 (100%), Positives = 610/610 (100%)
Query: 1 MQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANY 60
MQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANY
Sbjct: 1 MQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANY 60
Query: 61 NFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIM 120
NFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIM
Sbjct: 61 NFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIM 120
Query: 121 INFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADG 180
INFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADG
Sbjct: 121 INFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADG 180
Query: 181 EYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQP 240
EYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQP
Sbjct: 181 EYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQP 240
Query: 241 CKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCV 300
CKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCV
Sbjct: 241 CKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCV 300
Query: 301 FPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMG 360
FPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMG
Sbjct: 301 FPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMG 360
Query: 361 LEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICK 420
LEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICK
Sbjct: 361 LEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICK 420
Query: 421 QDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEE 480
QDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEE
Sbjct: 421 QDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEE 480
Query: 481 KAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWR 540
KAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWR
Sbjct: 481 KAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWR 540
Query: 541 YNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKF 600
YNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKF
Sbjct: 541 YNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKF 600
Query: 601 GSIKSDWLGC 610
GSIKSDWLGC
Sbjct: 601 GSIKSDWLGC 610
>gi|11342666 matrix metalloproteinase 2 isoform a preproprotein
[Homo sapiens]
Length = 660
Score = 1315 bits (3404), Expect = 0.0
Identities = 609/610 (99%), Positives = 610/610 (100%)
Query: 1 MQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANY 60
+QYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANY
Sbjct: 51 VQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANY 110
Query: 61 NFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIM 120
NFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIM
Sbjct: 111 NFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIM 170
Query: 121 INFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADG 180
INFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADG
Sbjct: 171 INFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADG 230
Query: 181 EYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQP 240
EYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQP
Sbjct: 231 EYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQP 290
Query: 241 CKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCV 300
CKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCV
Sbjct: 291 CKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCV 350
Query: 301 FPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMG 360
FPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMG
Sbjct: 351 FPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMG 410
Query: 361 LEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICK 420
LEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICK
Sbjct: 411 LEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICK 470
Query: 421 QDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEE 480
QDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEE
Sbjct: 471 QDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEE 530
Query: 481 KAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWR 540
KAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWR
Sbjct: 531 KAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWR 590
Query: 541 YNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKF 600
YNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKF
Sbjct: 591 YNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKF 650
Query: 601 GSIKSDWLGC 610
GSIKSDWLGC
Sbjct: 651 GSIKSDWLGC 660
>gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens]
Length = 707
Score = 601 bits (1550), Expect = e-172
Identities = 305/644 (47%), Positives = 401/644 (62%), Gaps = 59/644 (9%)
Query: 20 LKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRII 79
L L +QK LP+TG+LD T++ MR PRCG PD+ + F KW + ITY I
Sbjct: 67 LGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFQTFEGDLKWHHHNITYWIQ 126
Query: 80 GYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDG 139
Y+ DL +DDAFARAF +WS VTPL F+R++ +ADI+I FG EHGDGYPFDGKDG
Sbjct: 127 NYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDG 186
Query: 140 LLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTD 199
LLAHAF PG G+ GD+HFDDDELW+LG+G VV ++GNADG C FPF+F G+ Y++CT
Sbjct: 187 LLAHAFPPGPGIQGDAHFDDDELWSLGKGVVVPTRFGNADGAACHFPFIFEGRSYSACTT 246
Query: 200 TGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEG 259
GRSDG WCSTT N++ D ++GFCP E L+T GNA+G+PC+FPF FQG SY +CTT+G
Sbjct: 247 DGRSDGLPWCSTTANYDTDDRFGFCPSERLYTQDGNADGKPCQFPFIFQGQSYSACTTDG 306
Query: 260 RTDGYRWCGTTEDYDRDKKYGFCPETAMSTV-GGNSEGAPCVFPFTFLGNKYESCTSAGR 318
R+DGYRWC TT +YDRDK +GFCP A STV GGNS G CVFPFTFLG +Y +CTS GR
Sbjct: 307 RSDGYRWCATTANYDRDKLFGFCPTRADSTVMGGNSAGELCVFPFTFLGKEYSTCTSEGR 366
Query: 319 SDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYT 378
DG++WCATT+N+D D+KWGFCPDQGYSLFLVAAHEFGHA+GL+HS P ALM P+Y +T
Sbjct: 367 GDGRLWCATTSNFDSDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFT 426
Query: 379 KNFRLSQDDIKGIQELYGASPDID-----------------LGTGP-------TPTLGPV 414
+ L +DD+ GI+ LYG P+ + TGP PT GP
Sbjct: 427 EGPPLHKDDVNGIRHLYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSERPTAGPT 486
Query: 415 TP-------------------------EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTP 449
P + C +I FD IA+I +++ FKD WR
Sbjct: 487 GPPSAGPTGPPTAGPSTATTVPLSPVDDACNVNI-FDAIAEIGNQLYLFKDGKYWRFSEG 545
Query: 450 R-DKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTS 508
R +P GP L+A WP LP K+D+V+E +K FF+G + W+Y+ +++ P+ L
Sbjct: 546 RGSRPQGPFLIADKWPALPRKLDSVFEERLSKKLFFFSGRQVWVYTGASVLG--PRRLDK 603
Query: 509 LGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLD 568
LGL DV +V A S K +F+G + WR++ + +DP + + +P LD
Sbjct: 604 LGLGADVAQVTGALR-SGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVP--LD 660
Query: 569 AVVDLQGGGHSYFFKGAYYLKLENQS-LKSV-KFGSIKSDWLGC 610
Q +YF + +Y ++ ++S L V + G + D L C
Sbjct: 661 THDVFQYREKAYFCQDRFYWRVSSRSELNQVDQVGYVTYDILQC 704
>gi|4505209 matrix metalloproteinase 13 preproprotein [Homo sapiens]
Length = 471
Score = 223 bits (568), Expect = 4e-58
Identities = 112/258 (43%), Positives = 157/258 (60%), Gaps = 12/258 (4%)
Query: 329 ANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYT--KNFRLSQD 386
A++DDD W +GY+LFLVAAHEFGH++GL+HS+DPGALM PIYTYT +F L D
Sbjct: 199 AHFDDDETWT-SSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDD 257
Query: 387 DIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRT 446
D++GIQ LYG + P P P TP+ C + D I +RGE FKDRF WR
Sbjct: 258 DVQGIQSLYGPGDE-----DPNPK-HPKTPDKCDPSLSLDAITSLRGETMIFKDRFFWR- 310
Query: 447 VTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPL 506
+ P+ L +FWPELP +IDA YE P + F G ++W + + GYPK +
Sbjct: 311 LHPQQVDAELFLTKSFWPELPNRIDAAYEHPSHDLIFIFRGRKFWALNGYDILEGYPKKI 370
Query: 507 TSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDN 566
+ LGLP +V+++ AA ++ KT +F+G++ WRY++ MD +P+LI + + I D
Sbjct: 371 SELGLPKEVKKISAAVHFEDTGKTLLFSGNQVWRYDDTNHIMDKDYPRLIEEDFPGIGDK 430
Query: 567 LDAVVDLQGGGHSYFFKG 584
+DAV + G+ YFF G
Sbjct: 431 VDAV--YEKNGYIYFFNG 446
Score = 206 bits (525), Expect = 4e-53
Identities = 98/169 (57%), Positives = 119/169 (70%), Gaps = 7/169 (4%)
Query: 2 QYLNTFY------GCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNP 55
+YL ++Y G KE+ + + L++MQ FFGL TG LD NT++ M+KPRCG P
Sbjct: 41 RYLRSYYHPTNLAGILKENA-ASSMTERLREMQSFFGLEVTGKLDDNTLDVMKKPRCGVP 99
Query: 56 DVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDG 115
DV YN FPR KW K +TYRI+ YTPD+ V+ AF +AF+VWSDVTPL F+R+HDG
Sbjct: 100 DVGEYNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDG 159
Query: 116 EADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWT 164
ADIMI+FG EHGD YPFDG GLLAHAF PG GGD+HFDDDE WT
Sbjct: 160 IADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWT 208
>gi|4505217 matrix metalloproteinase 3 preproprotein [Homo sapiens]
Length = 477
Score = 219 bits (557), Expect = 8e-57
Identities = 119/289 (41%), Positives = 166/289 (57%), Gaps = 13/289 (4%)
Query: 329 ANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIY---TYTKNFRLSQ 385
A++DDD +W G +LFLVAAHE GH++GL HS + ALM P+Y T FRLSQ
Sbjct: 195 AHFDDDEQWTK-DTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQ 253
Query: 386 DDIKGIQELYGASPDID----LGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDR 441
DDI GIQ LYG PD + T P P P TP C + FD ++ +RGEI FKDR
Sbjct: 254 DDINGIQSLYGPPPDSPETPLVPTEPVPP-EPGTPANCDPALSFDAVSTLRGEILIFKDR 312
Query: 442 FIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERG 501
WR + +P L +++FWP LP +DA YE ++ F GN++W + + G
Sbjct: 313 HFWRKSLRKLEPELHL-ISSFWPSLPSGVDAAYEVTSKDLVFIFKGNQFWAIRGNEVRAG 371
Query: 502 YPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWN 561
YP+ + +LG PP V+++DAA + + KTY F DK+WR++E + M+PGFPK IA+ +
Sbjct: 372 YPRGIHTLGFPPTVRKIDAAISDKEKNKTYFFVEDKYWRFDEKRNSMEPGFPKQIAEDFP 431
Query: 562 AIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC 610
I +DAV + G YFF G+ L+ + + K V + WL C
Sbjct: 432 GIDSKIDAV--FEEFGFFYFFTGSSQLEFD-PNAKKVTHTLKSNSWLNC 477
Score = 196 bits (499), Expect = 4e-50
Identities = 91/169 (53%), Positives = 116/169 (68%), Gaps = 6/169 (3%)
Query: 2 QYLNTFYGCPKESCNLFVLKDT------LKKMQKFFGLPQTGDLDQNTIETMRKPRCGNP 55
+YL +Y K+ KD+ +++MQKF GL TG LD +T+E MRKPRCG P
Sbjct: 36 KYLENYYDLKKDVKQFVRRKDSGPVVKKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVP 95
Query: 56 DVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDG 115
DV ++ FP PKW K +TYRI+ YTPDL + VD A +A +VW +VTPL FSR+++G
Sbjct: 96 DVGHFRTFPGIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEG 155
Query: 116 EADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWT 164
EADIMI+F EHGD YPFDG +LAHA+APG G+ GD+HFDDDE WT
Sbjct: 156 EADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWT 204
>gi|225543094 matrix metalloproteinase 1 isoform 2 [Homo sapiens]
Length = 403
Score = 218 bits (554), Expect = 2e-56
Identities = 115/285 (40%), Positives = 162/285 (56%), Gaps = 16/285 (5%)
Query: 329 ANYDDDRKW--GFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQD 386
A++D+D +W F + Y+L VAAHE GH++GL HS D GALM P YT++ + +L+QD
Sbjct: 129 AHFDEDERWTNNF---REYNLHRVAAHELGHSLGLSHSTDIGALMYPSYTFSGDVQLAQD 185
Query: 387 DIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRT 446
DI GIQ +YG S + P +GP TP+ C + FD I IRGE+ FFKDRF RT
Sbjct: 186 DIDGIQAIYGRSQN------PVQPIGPQTPKACDSKLTFDAITTIRGEVMFFKDRFYMRT 239
Query: 447 VTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPL 506
P + ++ FWP+LP ++A YE ++ FF GN+YW + GYPK +
Sbjct: 240 -NPFYPEVELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGYPKDI 298
Query: 507 -TSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPD 565
+S G P V+ +DAA + KTY F +K+WRY+E K+ MDPG+PK+IA + I
Sbjct: 299 YSSFGFPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFPGIGH 358
Query: 566 NLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC 610
+DAV G YFF G K + ++ + + S W C
Sbjct: 359 KVDAV--FMKDGFFYFFHGTRQYKFDPKTKRILTLQKANS-WFNC 400
Score = 170 bits (431), Expect = 3e-42
Identities = 76/138 (55%), Positives = 99/138 (71%)
Query: 27 MQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLD 86
MQ+FFGL TG D T++ M++PRCG PDVA + P+W++ +TYRI YTPDL
Sbjct: 1 MQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIENYTPDLP 60
Query: 87 PETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFA 146
VD A +AFQ+WS+VTPL F+++ +G+ADIMI+F R +H D PFDG G LAHAF
Sbjct: 61 RADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGNLAHAFQ 120
Query: 147 PGTGVGGDSHFDDDELWT 164
PG G+GGD+HFD+DE WT
Sbjct: 121 PGPGIGGDAHFDEDERWT 138
>gi|4505215 matrix metalloproteinase 1 isoform 1 preproprotein [Homo
sapiens]
Length = 469
Score = 218 bits (554), Expect = 2e-56
Identities = 115/285 (40%), Positives = 162/285 (56%), Gaps = 16/285 (5%)
Query: 329 ANYDDDRKW--GFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQD 386
A++D+D +W F + Y+L VAAHE GH++GL HS D GALM P YT++ + +L+QD
Sbjct: 195 AHFDEDERWTNNF---REYNLHRVAAHELGHSLGLSHSTDIGALMYPSYTFSGDVQLAQD 251
Query: 387 DIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRT 446
DI GIQ +YG S + P +GP TP+ C + FD I IRGE+ FFKDRF RT
Sbjct: 252 DIDGIQAIYGRSQN------PVQPIGPQTPKACDSKLTFDAITTIRGEVMFFKDRFYMRT 305
Query: 447 VTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPL 506
P + ++ FWP+LP ++A YE ++ FF GN+YW + GYPK +
Sbjct: 306 -NPFYPEVELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGYPKDI 364
Query: 507 -TSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPD 565
+S G P V+ +DAA + KTY F +K+WRY+E K+ MDPG+PK+IA + I
Sbjct: 365 YSSFGFPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFPGIGH 424
Query: 566 NLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC 610
+DAV G YFF G K + ++ + + S W C
Sbjct: 425 KVDAV--FMKDGFFYFFHGTRQYKFDPKTKRILTLQKANS-WFNC 466
Score = 174 bits (442), Expect = 2e-43
Identities = 78/143 (54%), Positives = 103/143 (72%)
Query: 22 DTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGY 81
+ LK+MQ+FFGL TG D T++ M++PRCG PDVA + P+W++ +TYRI Y
Sbjct: 62 EKLKQMQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIENY 121
Query: 82 TPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLL 141
TPDL VD A +AFQ+WS+VTPL F+++ +G+ADIMI+F R +H D PFDG G L
Sbjct: 122 TPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGNL 181
Query: 142 AHAFAPGTGVGGDSHFDDDELWT 164
AHAF PG G+GGD+HFD+DE WT
Sbjct: 182 AHAFQPGPGIGGDAHFDEDERWT 204
>gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein
[Homo sapiens]
Length = 607
Score = 216 bits (550), Expect = 5e-56
Identities = 128/317 (40%), Positives = 167/317 (52%), Gaps = 41/317 (12%)
Query: 330 NYDDDRKW--GFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTY--TKNFRLSQ 385
++D D W G G LFLVA HE GHA+GLEHS DP A+MAP Y Y T NF+L
Sbjct: 221 HFDSDEPWTLGNPNHDGNDLFLVAVHELGHALGLEHSNDPTAIMAPFYQYMETDNFKLPN 280
Query: 386 DDIKGIQELYGASPDIDLGTGPTPTLGP-----------------------------VTP 416
DD++GIQ++YG I T P PT+ P P
Sbjct: 281 DDLQGIQKIYGPPDKIPPPTRPLPTVPPHRSIPPADPRKNDRPKPPRPPTGRPSYPGAKP 340
Query: 417 EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEA 476
IC D F+ +A +R E+F FKD++ WR R P+ + FW LP IDAVYE
Sbjct: 341 NIC--DGNFNTLAILRREMFVFKDQWFWRVRNNRVMDGYPMQITYFWRGLPPSIDAVYEN 398
Query: 477 PQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGD 536
+ VFF GN+YW++ +TL+ GYP L +LG +D+A W KTY F GD
Sbjct: 399 -SDGNFVFFKGNKYWVFKDTTLQPGYPHDLITLGSGIPPHGIDSAIWWEDVGKTYFFKGD 457
Query: 537 KFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLK 596
++WRY+E K MDPG+PK I W IP++ + G +YF+KG Y K NQ LK
Sbjct: 458 RYWRYSEEMKTMDPGYPKPIT-VWKGIPESPQGAFVHKENGFTYFYKGKEYWKFNNQILK 516
Query: 597 SVKFG---SIKSDWLGC 610
V+ G SI D++GC
Sbjct: 517 -VEPGYPRSILKDFMGC 532
Score = 137 bits (344), Expect = 4e-32
Identities = 77/164 (46%), Positives = 97/164 (59%), Gaps = 18/164 (10%)
Query: 20 LKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVA--NYNFFPRKP-------KWD 70
++ L MQ+F+G+ TG +D+NTI+ M+KPRCG PD + F R+ KW
Sbjct: 69 MQSALAAMQQFYGINMTGKVDRNTIDWMKKPRCGVPDQTRGSSKFHIRRKRYALTGQKWQ 128
Query: 71 KNQITYRIIGYTPDL-DPETVDDAFARAFQVWSDVTPLRF-----SRIHDG--EADIMIN 122
ITY I TP + DPET A RAF VW +VTPL F S + +G + DI I
Sbjct: 129 HKHITYSIKNVTPKVGDPET-RKAIRRAFDVWQNVTPLTFEEVPYSELENGKRDVDITII 187
Query: 123 FGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLG 166
F HGD PFDG+ G LAHA+ PG G+GGD+HFD DE WTLG
Sbjct: 188 FASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLG 231
>gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens]
Length = 645
Score = 216 bits (550), Expect = 5e-56
Identities = 127/318 (39%), Positives = 169/318 (53%), Gaps = 42/318 (13%)
Query: 330 NYDDDRKW--GFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTY--TKNFRLSQ 385
++D D W G G LFLVA HE GHA+GLEHS DP A+MAP Y Y T NF+L Q
Sbjct: 257 HFDSDEPWTLGNANHDGNDLFLVAVHELGHALGLEHSSDPSAIMAPFYQYMETHNFKLPQ 316
Query: 386 DDIKGIQELYGASPDIDLGTGPTPTLG--------------------------PVTP--- 416
DD++GIQ++YG + T P PTL P TP
Sbjct: 317 DDLQGIQKIYGPPAEPLEPTRPLPTLPVRRIHSPSERKHERQPRPPRPPLGDRPSTPGTK 376
Query: 417 -EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYE 475
IC D F+ +A RGE+F FKDR+ WR R + P+ + FW LP +IDA YE
Sbjct: 377 PNIC--DGNFNTVALFRGEMFVFKDRWFWRLRNNRVQEGYPMQIEQFWKGLPARIDAAYE 434
Query: 476 APQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAG 535
+ + VFF G++YW++ T+E GYP L LG + +D A W KTY F G
Sbjct: 435 RA-DGRFVFFKGDKYWVFKEVTVEPGYPHSLGELGSCLPREGIDTALRWEPVGKTYFFKG 493
Query: 536 DKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSL 595
+++WRY+E ++ DPG+PK I W IP + G ++YF+KG Y K +NQ L
Sbjct: 494 ERYWRYSEERRATDPGYPKPIT-VWKGIPQAPQGAFISKEGYYTYFYKGRDYWKFDNQKL 552
Query: 596 KSVKFG---SIKSDWLGC 610
SV+ G +I DW+GC
Sbjct: 553 -SVEPGYPRNILRDWMGC 569
Score = 144 bits (363), Expect = 2e-34
Identities = 77/161 (47%), Positives = 93/161 (57%), Gaps = 14/161 (8%)
Query: 20 LKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVA-------NYNFFPRKPKWDKN 72
L+ + MQ+F+G+P TG LDQ TIE M+KPRCG PD N + KW +
Sbjct: 107 LQSAVSTMQQFYGIPVTGVLDQTTIEWMKKPRCGVPDHPHLSRRRRNKRYALTGQKWRQK 166
Query: 73 QITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRI--HD-----GEADIMINFGR 125
ITY I YTP + A +AF VW VTPL F + H+ EADIMI F
Sbjct: 167 HITYSIHNYTPKVGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEIKSDRKEADIMIFFAS 226
Query: 126 WEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLG 166
HGD PFDG+ G LAHA+ PG G+GGD+HFD DE WTLG
Sbjct: 227 GFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLG 267
>gi|4505205 matrix metalloproteinase 10 preproprotein [Homo sapiens]
Length = 476
Score = 216 bits (549), Expect = 6e-56
Identities = 118/287 (41%), Positives = 165/287 (57%), Gaps = 11/287 (3%)
Query: 330 NYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIY---TYTKNFRLSQD 386
++DDD KW G +LFLVAAHE GH++GL HS + ALM P+Y T FRLSQD
Sbjct: 195 HFDDDEKWTE-DASGTNLFLVAAHELGHSLGLFHSANTEALMYPLYNSFTELAQFRLSQD 253
Query: 387 DIKGIQELYGASP-DIDLGTGPTPTL--GPVTPEICKQDIVFDGIAQIRGEIFFFKDRFI 443
D+ GIQ LYG P + PT ++ G P C + FD I+ +RGE FFKDR+
Sbjct: 254 DVNGIQSLYGPPPASTEEPLVPTKSVPSGSEMPAKCDPALSFDAISTLRGEYLFFKDRYF 313
Query: 444 WRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYP 503
WR +P L+ A FWP LP +DA YE + F GNE+W + ++ GYP
Sbjct: 314 WRRSHWNPEPEFHLISA-FWPSLPSYLDAAYEVNSRDTVFIFKGNEFWAIRGNEVQAGYP 372
Query: 504 KPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAI 563
+ + +LG PP ++++DAA + + KKTY FA DK+WR++E + M+ GFP+LIAD + +
Sbjct: 373 RGIHTLGFPPTIRKIDAAVSDKEKKKTYFFAADKYWRFDENSQSMEQGFPRLIADDFPGV 432
Query: 564 PDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC 610
+DAV LQ G YFF G+ + + + + V + WL C
Sbjct: 433 EPKVDAV--LQAFGFFYFFSGSSQFEFD-PNARMVTHILKSNSWLHC 476
Score = 187 bits (476), Expect = 2e-47
Identities = 92/170 (54%), Positives = 113/170 (66%), Gaps = 9/170 (5%)
Query: 2 QYLNTFYGCPKE-------SCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGN 54
QYL +Y K+ NL V K ++ MQKF GL TG LD +T+E MRKPRCG
Sbjct: 36 QYLEKYYNLEKDVKQFRRKDSNLIVKK--IQGMQKFLGLEVTGKLDTDTLEVMRKPRCGV 93
Query: 55 PDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHD 114
PDV +++ FP PKW K +TYRI+ YTPDL + VD A +A +VW +VTPL FSR+++
Sbjct: 94 PDVGHFSSFPGMPKWRKTHLTYRIVNYTPDLPRDAVDSAIEKALKVWEEVTPLTFSRLYE 153
Query: 115 GEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWT 164
GEADIMI+F EHGD Y FDG LAHA+ PG G+ GD HFDDDE WT
Sbjct: 154 GEADIMISFAVKEHGDFYSFDGPGHSLAHAYPPGPGLYGDIHFDDDEKWT 203
>gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens]
Length = 467
Score = 212 bits (539), Expect = 9e-55
Identities = 116/284 (40%), Positives = 157/284 (55%), Gaps = 15/284 (5%)
Query: 329 ANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTY--TKNFRLSQD 386
A++D + W Y+LFLVAAHEFGH++GL HS DPGALM P Y + T N+ L QD
Sbjct: 194 AHFDAEETWTNT-SANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNYAFRETSNYSLPQD 252
Query: 387 DIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRT 446
DI GIQ +YG L + P GP TP+ C + FD I +RGEI FFKDR+ WR
Sbjct: 253 DIDGIQAIYG------LSSNPIQPTGPSTPKPCDPSLTFDAITTLRGEILFFKDRYFWRR 306
Query: 447 VTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPL 506
P+ + + ++ FWP LP I A YE + F GN+YW S + +GYPK +
Sbjct: 307 -HPQLQRVEMNFISLFWPSLPTGIQAAYEDFDRDLIFLFKGNQYWALSGYDILQGYPKDI 365
Query: 507 TSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDN 566
++ G P VQ +DAA + KTY F D+FWRY+ ++ M+PG+PK I+ A+ I
Sbjct: 366 SNYGFPSSVQAIDAAVFY--RSKTYFFVNDQFWRYDNQRQFMEPGYPKSISGAFPGIESK 423
Query: 567 LDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC 610
+DAV + H + Y L Q + V G + WL C
Sbjct: 424 VDAVFQQEHFFHVFSGPRYYAFDLIAQRVTRVARG---NKWLNC 464
Score = 168 bits (426), Expect = 1e-41
Identities = 83/170 (48%), Positives = 107/170 (62%), Gaps = 10/170 (5%)
Query: 3 YLNTFYGCP--------KESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGN 54
YL FY P K N+ V K LK+MQ+FFGL TG ++ T++ M+KPRCG
Sbjct: 36 YLEKFYQLPSNQYQSTRKNGTNVIVEK--LKEMQRFFGLNVTGKPNEETLDMMKKPRCGV 93
Query: 55 PDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHD 114
PD + P PKW++ +TYRI YTP L V+ A AF++WS +PL F+RI
Sbjct: 94 PDSGGFMLTPGNPKWERTNLTYRIRNYTPQLSEAEVERAIKDAFELWSVASPLIFTRISQ 153
Query: 115 GEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWT 164
GEADI I F + +HGD PFDG +G+LAHAF PG G+GGD+HFD +E WT
Sbjct: 154 GEADINIAFYQRDHGDNSPFDGPNGILAHAFQPGQGIGGDAHFDAEETWT 203
>gi|4505211 matrix metalloproteinase 15 preproprotein [Homo sapiens]
Length = 669
Score = 204 bits (518), Expect = 3e-52
Identities = 119/330 (36%), Positives = 163/330 (49%), Gaps = 53/330 (16%)
Query: 330 NYDDDRKWGFCPDQ--GYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTY--TKNFRLSQ 385
++D D W F G +LFLVA HE GHA+GLEHS +P A+MAP Y + NF+L +
Sbjct: 234 HFDADEPWTFSSTDLHGNNLFLVAVHELGHALGLEHSSNPNAIMAPFYQWKDVDNFKLPE 293
Query: 386 DDIKGIQELYGASPDIDLGTGPTPTLGP-------------------------------- 413
DD++GIQ+LYG T P PT+ P
Sbjct: 294 DDLRGIQQLYGTPDGQPQPTQPLPTVTPRRPGRPDHRPPRPPQPPPPGGKPERPPKPGPP 353
Query: 414 -----------VTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATF 462
P IC D FD +A +RGE+F FK R+ WR R P+ + F
Sbjct: 354 VQPRATERPDQYGPNICDGD--FDTVAMLRGEMFVFKGRWFWRVRHNRVLDNYPMPIGHF 411
Query: 463 WPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAF 522
W LP I A YE Q+ + VFF G+ YW++ + LE GYP+PLTS GL R+D A
Sbjct: 412 WRGLPGDISAAYER-QDGRFVFFKGDRYWLFREANLEPGYPQPLTSYGLGIPYDRIDTAI 470
Query: 523 NWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFF 582
W T+ F D++WR+NE ++ DPG+PK I+ W IP + ++YF+
Sbjct: 471 WWEPTGHTFFFQEDRYWRFNEETQRGDPGYPKPIS-VWQGIPASPKGAFLSNDAAYTYFY 529
Query: 583 KGAYYLKLENQSLKSVKF--GSIKSDWLGC 610
KG Y K +N+ L+ SI D++GC
Sbjct: 530 KGTKYWKFDNERLRMEPGYPKSILRDFMGC 559
Score = 128 bits (321), Expect = 2e-29
Identities = 70/165 (42%), Positives = 90/165 (54%), Gaps = 19/165 (11%)
Query: 19 VLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDV----ANYNFFPRKP------- 67
+L L +MQ+F+G+P TG LD+ T E M++PRCG PD N R+
Sbjct: 78 ILASALAEMQRFYGIPVTGVLDEETKEWMKRPRCGVPDQFGVRVKANLRRRRKRYALTGR 137
Query: 68 KWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRI--------HDGEADI 119
KW+ + +T+ I YT L +A RAF+VW TPL F + EADI
Sbjct: 138 KWNNHHLTFSIQNYTEKLGWYHSMEAVRRAFRVWEQATPLVFQEVPYEDIRLRRQKEADI 197
Query: 120 MINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWT 164
M+ F HGD PFDG G LAHA+ PG G+GGD+HFD DE WT
Sbjct: 198 MVLFASGFHGDSSPFDGTGGFLAHAYFPGPGLGGDTHFDADEPWT 242
>gi|4826834 matrix metalloproteinase 14 preproprotein [Homo sapiens]
Length = 582
Score = 199 bits (505), Expect = 8e-51
Identities = 114/282 (40%), Positives = 156/282 (55%), Gaps = 18/282 (6%)
Query: 344 GYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTY--TKNFRLSQDDIKGIQELYGASPDI 401
G +FLVA HE GHA+GLEHS DP A+MAP Y + T+NF L DD +GIQ+LYG
Sbjct: 230 GNDIFLVAVHELGHALGLEHSSDPSAIMAPFYQWMDTENFVLPDDDRRGIQQLYGGESGF 289
Query: 402 DLGTGPTP--TLGPVTPEICKQ--------DIVFDGIAQIRGEIFFFKDRFIWRTVTPRD 451
P P T P P+ K D FD +A +RGE+F FK+R+ WR +
Sbjct: 290 PTKMPPQPRTTSRPSVPDKPKNPTYGPNICDGNFDTVAMLRGEMFVFKERWFWRVRNNQV 349
Query: 452 KPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGL 511
P+ + FW LP I+ YE ++ K VFF G+++W++ ++LE GYPK + LG
Sbjct: 350 MDGYPMPIGQFWRGLPASINTAYER-KDGKFVFFKGDKHWVFDEASLEPGYPKHIKELGR 408
Query: 512 PPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVV 571
++DAA W N KTY F G+K++R+NE + +D +PK I W IP++
Sbjct: 409 GLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNI-KVWEGIPESPRGSF 467
Query: 572 DLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKS---DWLGC 610
+YF+KG Y K NQ LK V+ G KS DW+GC
Sbjct: 468 MGSDEVFTYFYKGNKYWKFNNQKLK-VEPGYPKSALRDWMGC 508
Score = 135 bits (339), Expect = 1e-31
Identities = 69/163 (42%), Positives = 91/163 (55%), Gaps = 17/163 (10%)
Query: 20 LKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPD---------VANYNFFPRKPKWD 70
L + MQKF+GL TG D +T++ MR+PRCG PD V + + KW
Sbjct: 61 LSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGLKWQ 120
Query: 71 KNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRI--------HDGEADIMIN 122
N+IT+ I YTP + +A +AF+VW TPLRF + H+ +ADIMI
Sbjct: 121 HNEITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQADIMIF 180
Query: 123 FGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTL 165
F HGD PFDG+ G LAHA+ PG +GGD+HFD E WT+
Sbjct: 181 FAEGFHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTV 223
>gi|73858572 matrix metalloproteinase 12 preproprotein [Homo
sapiens]
Length = 470
Score = 191 bits (485), Expect = 2e-48
Identities = 108/290 (37%), Positives = 156/290 (53%), Gaps = 22/290 (7%)
Query: 329 ANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYT--KNFRLSQD 386
A++D+D W G +LFL A HE GH++GL HS DP A+M P Y Y FRLS D
Sbjct: 195 AHFDEDEFWT-THSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSAD 253
Query: 387 DIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRT 446
DI+GIQ LYG + P + P +C ++ FD + + +IFFFKDRF W
Sbjct: 254 DIRGIQSLYGDPKENQRLPNPDNS----EPALCDPNLSFDAVTTVGNKIFFFKDRFFWLK 309
Query: 447 VTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPL 506
V+ R K L+++ WP LP I+A YE + F ++YW+ S E YPK +
Sbjct: 310 VSERPKT-SVNLISSLWPTLPSGIEAAYEIEARNQVFLFKDDKYWLISNLRPEPNYPKSI 368
Query: 507 TSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDN 566
S G P V+++DAA + +TY F +++WRY+E ++ MDPG+PKLI + I
Sbjct: 369 HSFGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDERRQMMDPGYPKLITKNFQGIGPK 428
Query: 567 LDAVVDLQGGGHSYFFKGA------YYLKLENQSLKSVKFGSIKSDWLGC 610
+DAV + YFF+G+ + L+ ++LKS + W GC
Sbjct: 429 IDAVF-YSKNKYYYFFQGSNQFEYDFLLQRITKTLKS-------NSWFGC 470
Score = 187 bits (474), Expect = 3e-47
Identities = 92/176 (52%), Positives = 118/176 (67%), Gaps = 11/176 (6%)
Query: 2 QYLNTFYGCP---------KESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRC 52
+YL FYG K S NL +K+ +++MQ F GL TG LD +T+E M PRC
Sbjct: 35 RYLEKFYGLEINKLPVTKMKYSGNL--MKEKIQEMQHFLGLKVTGQLDTSTLEMMHAPRC 92
Query: 53 GNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRI 112
G PDV ++ P P W K+ ITYRI YTPD++ E VD A +AFQVWS+VTPL+FS+I
Sbjct: 93 GVPDVHHFREMPGGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKI 152
Query: 113 HDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEG 168
+ G ADI++ F R HGD + FDGK G+LAHAF PG+G+GGD+HFD+DE WT G
Sbjct: 153 NTGMADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSG 208
>gi|4505219 matrix metalloproteinase 7 preproprotein [Homo sapiens]
Length = 267
Score = 189 bits (481), Expect = 5e-48
Identities = 92/173 (53%), Positives = 109/173 (63%)
Query: 3 YLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNF 62
YL FY E+ N L+ LK+MQKFFGLP TG L+ IE M+KPRCG PDVA Y+
Sbjct: 38 YLKRFYLYDSETKNANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSL 97
Query: 63 FPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMIN 122
FP PKW +TYRI+ YT DL TVD ++A +W PL F ++ G ADIMI
Sbjct: 98 FPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIG 157
Query: 123 FGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKY 175
F R HGD YPFDG LAHAFAPGTG+GGD+HFD+DE WT G + Y
Sbjct: 158 FARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLY 210
Score = 74.7 bits (182), Expect = 2e-13
Identities = 40/98 (40%), Positives = 54/98 (55%), Gaps = 7/98 (7%)
Query: 301 FPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMG 360
+PF GN + G G A++D+D +W G + A HE GH++G
Sbjct: 167 YPFDGPGNTLAHAFAPGTGLGG-----DAHFDEDERWTDGSSLGINFLYAATHELGHSLG 221
Query: 361 LEHSQDPGALMAPIYTY--TKNFRLSQDDIKGIQELYG 396
+ HS DP A+M P Y +NF+LSQDDIKGIQ+LYG
Sbjct: 222 MGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYG 259
>gi|11968059 matrix metalloproteinase 25 preproprotein [Homo
sapiens]
Length = 562
Score = 188 bits (478), Expect = 1e-47
Identities = 114/312 (36%), Positives = 164/312 (52%), Gaps = 42/312 (13%)
Query: 330 NYDDDRKWGFCPD--QGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYT----KNFRL 383
++DD+ W F +G LF VA HEFGHA+GL HS P ++M P Y +RL
Sbjct: 208 HFDDEETWTFGSKDGEGTDLFAVAVHEFGHALGLGHSSAPNSIMRPFYQGPVGDPDKYRL 267
Query: 384 SQDDIKGIQELYGASPDID--------LGTGPTPTLGPV------TPEICKQDIVFDGIA 429
SQDD G+Q+LYG +P L P P P P+ C+ + FD IA
Sbjct: 268 SQDDRDGLQQLYGKAPQTPYDKPTRKPLAPPPQPPASPTHSPSFPIPDRCEGN--FDAIA 325
Query: 430 QIRGEIFFFKDRFIWRT------VTPRDKPMGPLLVATFWPELPEKI---DAVYEAPQEE 480
IRGE FFFK + WR V+PR P + FW LP ++ A Y ++
Sbjct: 326 NIRGETFFFKGPWFWRLQPSGQLVSPR-----PARLHRFWEGLPAQVRVVQAAYARHRDG 380
Query: 481 KAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWR 540
+ + F+G ++W++ LE G +PLT LGLPP + VDA F+W +N KTY+ G ++WR
Sbjct: 381 RILLFSGPQFWVFQDRQLEGG-ARPLTELGLPPG-EEVDAVFSWPQNGKTYLVRGRQYWR 438
Query: 541 YNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKF 600
Y+E + DPG+P+ ++ W P + D V + G +YFFKGA+Y + S+K+
Sbjct: 439 YDEAAARPDPGYPRDLS-LWEGAPPSPDDVT-VSNAGDTYFFKGAHYWRFPKNSIKTEPD 496
Query: 601 G--SIKSDWLGC 610
+ +WL C
Sbjct: 497 APQPMGPNWLDC 508
Score = 121 bits (304), Expect = 2e-27
Identities = 67/161 (41%), Positives = 88/161 (54%), Gaps = 14/161 (8%)
Query: 20 LKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPK--------WDK 71
L+D +K MQ+F GLP+TG +D T+ TMRKPRC PDV R+ + W K
Sbjct: 58 LRDAIKVMQRFAGLPETGRMDPGTVATMRKPRCSLPDVLGVAGLVRRRRRYALSGSVWKK 117
Query: 72 NQITYRIIGY--TPDLDPETVDDAFARAFQVWSDVTPLRFSRI---HDGEADIMINFGRW 126
+T+R+ + + L ETV + A W + L F + E DI+I+F R
Sbjct: 118 RTLTWRVRSFPQSSQLSQETVRVLMSYALMAWGMESGLTFHEVDSPQGQEPDILIDFARA 177
Query: 127 EHGDGYPFDGKDGLLAHAFAPGT-GVGGDSHFDDDELWTLG 166
H D YPFDG G LAHAF PG + GD+HFDD+E WT G
Sbjct: 178 FHQDSYPFDGLGGTLAHAFFPGEHPISGDTHFDDEETWTFG 218
>gi|45359865 matrix metalloproteinase 20 preproprotein [Homo
sapiens]
Length = 483
Score = 187 bits (475), Expect = 2e-47
Identities = 85/143 (59%), Positives = 101/143 (70%)
Query: 24 LKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTP 83
+K++Q FFGL TG LDQ T+ ++KPRCG PDVANY FP +PKW KN +TYRI YTP
Sbjct: 72 IKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYRLFPGEPKWKKNTLTYRISKYTP 131
Query: 84 DLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAH 143
+ VD A A Q WS PL F RI+ GEADIMI+F +HGD YPFDG G LAH
Sbjct: 132 SMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHGDSYPFDGPRGTLAH 191
Query: 144 AFAPGTGVGGDSHFDDDELWTLG 166
AFAPG G+GGD+HFD+ E WT+G
Sbjct: 192 AFAPGEGLGGDTHFDNAEKWTMG 214
Score = 184 bits (468), Expect = 2e-46
Identities = 107/289 (37%), Positives = 154/289 (53%), Gaps = 17/289 (5%)
Query: 330 NYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTK--NFRLSQDD 387
++D+ KW + G++LF VAAHEFGHA+GL HS DP ALM P Y Y F L +DD
Sbjct: 204 HFDNAEKWTMGTN-GFNLFTVAAHEFGHALGLAHSTDPSALMYPTYKYKNPYGFHLPKDD 262
Query: 388 IKGIQELYGASPDIDLGTGPT----PTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFI 443
+KGIQ LYG + LG PT P P P++C FD + + E+ FKDR
Sbjct: 263 VKGIQALYGPRK-VFLGK-PTLPHAPHHKPSIPDLCDSSSSFDAVTMLGKELLLFKDRIF 320
Query: 444 WRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYP 503
WR + P + + +P+L +DA YE + A FF G YWI ++ G P
Sbjct: 321 WRRQVHLRTGIRPSTITSSFPQLMSNVDAAYEVAERGTAYFFKGPHYWITRGFQMQ-GPP 379
Query: 504 KPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAI 563
+ + G P VQ++DAA + +KT F GD+++ Y+E K+KM+ +PK + ++ +
Sbjct: 380 RTIYDFGFPRHVQQIDAAVYLREPQKTLFFVGDEYYSYDERKRKMEKDYPKNTEEEFSGV 439
Query: 564 PDNLDAVVDLQGGGHSYFFKG--AYYLKLENQSLKSVKFGSIKSDWLGC 610
+DA V+L G+ YFF G Y E + + SV S W+GC
Sbjct: 440 NGQIDAAVEL--NGYIYFFSGPKTYKYDTEKEDVVSV---VKSSSWIGC 483
>gi|112382270 matrix metalloproteinase 17 preproprotein [Homo
sapiens]
Length = 603
Score = 181 bits (459), Expect = 2e-45
Identities = 109/309 (35%), Positives = 155/309 (50%), Gaps = 28/309 (9%)
Query: 326 ATTANYDDDRKWGFCPDQ--GYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKN--- 380
A ++DDD W F G LF VA HEFGHA+GL H ++M P Y
Sbjct: 219 AGDTHFDDDEAWTFRSSDAHGMDLFAVAVHEFGHAIGLSHVAAAHSIMRPYYQGPVGDPL 278
Query: 381 -FRLSQDDIKGIQELYGASPDIDLGTGPT-PTLGPVTPEIC-----KQDIV------FDG 427
+ L +D + +LYG + P P L P P+ ++D+ FD
Sbjct: 279 RYGLPYEDKVRVWQLYGVRESVSPTAQPEEPPLLPEPPDNRSSAPPRKDVPHRCSTHFDA 338
Query: 428 IAQIRGEIFFFKDRFIWRTVTPRDK-PMGPLLVATFWPELP---EKIDAVYEAPQEEKAV 483
+AQIRGE FFFK ++ WR R + P + FW LP + +DAVYE + K V
Sbjct: 339 VAQIRGEAFFFKGKYFWRLTRDRHLVSLQPAQMHRFWRGLPLHLDSVDAVYERTSDHKIV 398
Query: 484 FFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNE 543
FF G+ YW++ + +E GYP+P++ LPP +DAAF+W+ N +TY F +WRY++
Sbjct: 399 FFKGDRYWVFKDNNVEEGYPRPVSDFSLPPG--GIDAAFSWAHNDRTYFFKDQLYWRYDD 456
Query: 544 VKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKF--G 601
+ MDPG+P + W +P LD + G SYFF+G Y K+ + L+
Sbjct: 457 HTRHMDPGYPAQ-SPLWRGVPSTLDDAMRWSDGA-SYFFRGQEYWKVLDGELEVAPGYPQ 514
Query: 602 SIKSDWLGC 610
S DWL C
Sbjct: 515 STARDWLVC 523
Score = 121 bits (303), Expect = 2e-27
Identities = 64/154 (41%), Positives = 85/154 (55%), Gaps = 9/154 (5%)
Query: 20 LKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVA------NYNFFPRKPKWDKNQ 73
L + MQ+F GL TG LD+ T+ M+ PRC PD+ P KW+K
Sbjct: 78 LSKAITAMQQFGGLEATGILDEATLALMKTPRCSLPDLPVLTQARRRRQAPAPTKWNKRN 137
Query: 74 ITYRIIGYTPD--LDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDG 131
+++R+ + D L +TV A +VWSD+ PL F + ADI I+F + +H DG
Sbjct: 138 LSWRVRTFPRDSPLGHDTVRALMYYALKVWSDIAPLNFHEVAGSAADIQIDFSKADHNDG 197
Query: 132 YPFDGKDGLLAHAFAPG-TGVGGDSHFDDDELWT 164
YPFDG G +AHAF PG GD+HFDDDE WT
Sbjct: 198 YPFDGPGGTVAHAFFPGHHHTAGDTHFDDDEAWT 231
>gi|73808268 matrix metalloproteinase 27 [Homo sapiens]
Length = 513
Score = 174 bits (441), Expect = 2e-43
Identities = 102/272 (37%), Positives = 144/272 (52%), Gaps = 22/272 (8%)
Query: 330 NYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYT--KNFRLSQDD 387
++D+D W G++LFLVAAHEFGHA+GL HS D ALM P Y + + LSQDD
Sbjct: 194 HFDEDENWTK-DGAGFNLFLVAAHEFGHALGLSHSNDQTALMFPNYVSLDPRKYPLSQDD 252
Query: 388 IKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRT- 446
I GIQ +YG P P P P C D+ FD I R E+ FFK R +WR
Sbjct: 253 INGIQSIYGGLPK-----EPAKPKEPTIPHACDPDLTFDAITTFRREVMFFKGRHLWRIY 307
Query: 447 --VTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPK 504
+T + L+A+FWP LP + A YE P++ K + F +W+ + YPK
Sbjct: 308 YDITDVEFE----LIASFWPSLPADLQAAYENPRD-KILVFKDENFWMIRGYAVLPDYPK 362
Query: 505 PLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIP 564
+ +LG P V+++DAA +KTY F G WR++E+ + MD GFP+ + + I
Sbjct: 363 SIHTLGFPGRVKKIDAAVCDKTTRKTYFFVGIWCWRFDEMTQTMDKGFPQRVVKHFPGIS 422
Query: 565 DNLDAVVDLQGGGHSYFFKGA----YYLKLEN 592
+DA Q G +F +G+ Y +K +N
Sbjct: 423 IRVDAA--FQYKGFFFFSRGSKQFEYDIKTKN 452
Score = 161 bits (407), Expect = 2e-39
Identities = 85/169 (50%), Positives = 104/169 (61%), Gaps = 9/169 (5%)
Query: 3 YLNTFYGCPKE------SCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPD 56
YLN FY E S N ++ D +++MQ FFGL TG LD NT+E M+ PRCG PD
Sbjct: 36 YLNQFYSLEIEGNHLVQSKNRSLIDDKIREMQAFFGLTVTGKLDSNTLEIMKTPRCGVPD 95
Query: 57 VANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGE 116
V Y + P W K +TYRII YTPD+ VD+A +VWS VTPL+F++I G
Sbjct: 96 VGQYGY--TLPGWRKYNLTYRIINYTPDMARAAVDEAIQEGLEVWSKVTPLKFTKISKGI 153
Query: 117 ADIMINFGRWEHGD-GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWT 164
ADIMI F HG FDG G+L HAF PG G+GGD+HFD+DE WT
Sbjct: 154 ADIMIAFRTRVHGRCPRYFDGPLGVLGHAFPPGPGLGGDTHFDEDENWT 202
>gi|58331148 matrix metalloproteinase 11 preproprotein [Homo
sapiens]
Length = 488
Score = 170 bits (430), Expect = 4e-42
Identities = 106/300 (35%), Positives = 148/300 (49%), Gaps = 30/300 (10%)
Query: 330 NYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIK 389
++D D W DQG L VAAHEFGH +GL+H+ ALM+ YT+ LS DD +
Sbjct: 192 HFDYDETWTIGDDQGTDLLQVAAHEFGHVLGLQHTTAAKALMSAFYTFRYPLSLSPDDCR 251
Query: 390 GIQELYGAS-PDIDLGTGPTPTLGP---------------VTPEICKQDIVFDGIAQIRG 433
G+Q LYG P + T TP LGP P+ C+ FD ++ IRG
Sbjct: 252 GVQHLYGQPWPTV---TSRTPALGPQAGIDTNEIAPLEPDAPPDACEAS--FDAVSTIRG 306
Query: 434 EIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIY 493
E+FFFK F+WR + +P P L + W LP +DA +E Q FF G +YW+Y
Sbjct: 307 ELFFFKAGFVWRLRGGQLQPGYPALASRHWQGLPSPVDAAFEDAQGH-IWFFQGAQYWVY 365
Query: 494 SASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNK-KTYIFAGDKFWRYNEVKKKMDPGF 552
G P PLT LGL V AA W K K Y F G +WR++ +++D
Sbjct: 366 DGEKPVLG-PAPLTELGLVR--FPVHAALVWGPEKNKIYFFRGRDYWRFHPSTRRVDSPV 422
Query: 553 PKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKF--GSIKSDWLGC 610
P+ D W +P +DA G++YF +G Y K + +K+++ + D+ GC
Sbjct: 423 PRRATD-WRGVPSEIDAAFQ-DADGYAYFLRGRLYWKFDPVKVKALEGFPRLVGPDFFGC 480
Score = 129 bits (323), Expect = 1e-29
Identities = 63/132 (47%), Positives = 81/132 (61%), Gaps = 8/132 (6%)
Query: 46 TMRKPRCGNPDVAN--------YNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARA 97
++R PRCG PD ++ F +W+K +TYRI+ + L E V A A
Sbjct: 74 SLRPPRCGVPDPSDGLSARNRQKRFVLSGGRWEKTDLTYRILRFPWQLVQEQVRQTMAEA 133
Query: 98 FQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHF 157
+VWSDVTPL F+ +H+G ADIMI+F R+ HGD PFDG G+LAHAF P T GD HF
Sbjct: 134 LKVWSDVTPLTFTEVHEGRADIMIDFARYWHGDDLPFDGPGGILAHAFFPKTHREGDVHF 193
Query: 158 DDDELWTLGEGQ 169
D DE WT+G+ Q
Sbjct: 194 DYDETWTIGDDQ 205
>gi|4505213 matrix metalloproteinase 19 isoform rasi-1 preproprotein
[Homo sapiens]
Length = 508
Score = 151 bits (381), Expect = 2e-36
Identities = 99/297 (33%), Positives = 153/297 (51%), Gaps = 25/297 (8%)
Query: 328 TANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYT-YTKNFRLSQD 386
+ ++D+D W +G +L ++AAHE GHA+GL HS+ ALMAP+Y Y +F+L D
Sbjct: 187 SVHFDEDEFWTEGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYEGYRPHFKLHPD 246
Query: 387 DIKGIQELYG-ASP--------DIDLGT-GPTPTLGPVTPEICKQDIVFDGIAQIRGEIF 436
D+ GIQ LYG SP + +L T P PT P+ C ++ + RG+ +
Sbjct: 247 DVAGIQALYGKKSPVIRDEEEEETELPTVPPVPTEPSPMPDPCSSELDAMMLGP-RGKTY 305
Query: 437 FFKDRFIWRTVTPRDKPMGPLL-VATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSA 495
FK ++W T D GPL V+ W LP +DA +P+ + FF G++ W Y
Sbjct: 306 AFKGDYVW---TVSDSGPGPLFRVSALWEGLPGNLDAAVYSPRTQWIHFFKGDKVWRYIN 362
Query: 496 STLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKL 555
+ G+PK L + +DAA W N+K ++F G +W+++E+ + +PK
Sbjct: 363 FKMSPGFPKKLNRV-----EPNLDAALYWPLNQKVFLFKGSGYWQWDELARTDFSSYPKP 417
Query: 556 IADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKF--GSIKSDWLGC 610
I + +P+ A + Q G YFFKG Y +L NQ L+ K +I +W+ C
Sbjct: 418 IKGLFTGVPNQPSAAMSWQ-DGRVYFFKGKVYWRL-NQQLRVEKGYPRNISHNWMHC 472
Score = 98.6 bits (244), Expect = 1e-20
Identities = 64/170 (37%), Positives = 84/170 (49%), Gaps = 9/170 (5%)
Query: 11 PKESCNLFVLKD---TLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNF--FPR 65
P E N F +D L+ Q+ LP +G LD T MR+PRCG D N +
Sbjct: 41 PLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLL 100
Query: 66 KPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINF-G 124
+W K +T+RI+ L P T A +AFQ WS+V PL F + G ADI ++F G
Sbjct: 101 LGRWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHG 160
Query: 125 RWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVK 174
R FDG +LAHA P G HFD+DE WT G + V ++
Sbjct: 161 RQSSYCSNTFDGPGRVLAHADIPEL---GSVHFDEDEFWTEGTYRGVNLR 207
>gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens]
Length = 2355
Score = 146 bits (368), Expect = 6e-35
Identities = 70/178 (39%), Positives = 97/178 (54%), Gaps = 16/178 (8%)
Query: 167 EGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPH 226
E V + GN++GE C PF +NG+ + SCT GR DG LWCSTT N+E+D KY FC
Sbjct: 344 ETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTD 403
Query: 227 EALF--TMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE 284
+ T GGN+ G C FPF + +Y CT+EGR D +WCGTT++YD D+K+GFCP
Sbjct: 404 HTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPM 463
Query: 285 TAMSTVGGNSEGAPCVFPFTFLGNKYES---------CTSAGRSDGKMWCATTANYDD 333
A + +EG +G++++ CT G G+ C + D
Sbjct: 464 AAHEEICTTNEGV-----MYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRD 516
Score = 145 bits (365), Expect = 1e-34
Identities = 77/171 (45%), Positives = 97/171 (56%), Gaps = 18/171 (10%)
Query: 194 YNSC-TDTG--RSDGFLWCSTTYNFEKD----GKYGFCPHEALF-TMGGNAEGQPCKFPF 245
Y C TD+G S G W T N + G C A+ T GGN+ G+PC PF
Sbjct: 305 YGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPF 364
Query: 246 RFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE--TAMSTVGGNSEGAPCVFPF 303
+ G ++ SCTTEGR DG+ WC TT +Y++D+KY FC + + T GGNS GA C FPF
Sbjct: 365 TYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPF 424
Query: 304 TFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHE 354
+ + Y CTS GR D WC TT NYD D+K+GFCP +AAHE
Sbjct: 425 LYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCP--------MAAHE 467
>gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens]
Length = 2477
Score = 146 bits (368), Expect = 6e-35
Identities = 70/178 (39%), Positives = 97/178 (54%), Gaps = 16/178 (8%)
Query: 167 EGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPH 226
E V + GN++GE C PF +NG+ + SCT GR DG LWCSTT N+E+D KY FC
Sbjct: 344 ETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTD 403
Query: 227 EALF--TMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE 284
+ T GGN+ G C FPF + +Y CT+EGR D +WCGTT++YD D+K+GFCP
Sbjct: 404 HTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPM 463
Query: 285 TAMSTVGGNSEGAPCVFPFTFLGNKYES---------CTSAGRSDGKMWCATTANYDD 333
A + +EG +G++++ CT G G+ C + D
Sbjct: 464 AAHEEICTTNEGV-----MYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRD 516
Score = 145 bits (365), Expect = 1e-34
Identities = 77/171 (45%), Positives = 97/171 (56%), Gaps = 18/171 (10%)
Query: 194 YNSC-TDTG--RSDGFLWCSTTYNFEKD----GKYGFCPHEALF-TMGGNAEGQPCKFPF 245
Y C TD+G S G W T N + G C A+ T GGN+ G+PC PF
Sbjct: 305 YGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPF 364
Query: 246 RFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE--TAMSTVGGNSEGAPCVFPF 303
+ G ++ SCTTEGR DG+ WC TT +Y++D+KY FC + + T GGNS GA C FPF
Sbjct: 365 TYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPF 424
Query: 304 TFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHE 354
+ + Y CTS GR D WC TT NYD D+K+GFCP +AAHE
Sbjct: 425 LYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCP--------MAAHE 467
>gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens]
Length = 2330
Score = 146 bits (368), Expect = 6e-35
Identities = 70/178 (39%), Positives = 97/178 (54%), Gaps = 16/178 (8%)
Query: 167 EGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPH 226
E V + GN++GE C PF +NG+ + SCT GR DG LWCSTT N+E+D KY FC
Sbjct: 344 ETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTD 403
Query: 227 EALF--TMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE 284
+ T GGN+ G C FPF + +Y CT+EGR D +WCGTT++YD D+K+GFCP
Sbjct: 404 HTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPM 463
Query: 285 TAMSTVGGNSEGAPCVFPFTFLGNKYES---------CTSAGRSDGKMWCATTANYDD 333
A + +EG +G++++ CT G G+ C + D
Sbjct: 464 AAHEEICTTNEGV-----MYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRD 516
Score = 145 bits (365), Expect = 1e-34
Identities = 77/171 (45%), Positives = 97/171 (56%), Gaps = 18/171 (10%)
Query: 194 YNSC-TDTG--RSDGFLWCSTTYNFEKD----GKYGFCPHEALF-TMGGNAEGQPCKFPF 245
Y C TD+G S G W T N + G C A+ T GGN+ G+PC PF
Sbjct: 305 YGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPF 364
Query: 246 RFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE--TAMSTVGGNSEGAPCVFPF 303
+ G ++ SCTTEGR DG+ WC TT +Y++D+KY FC + + T GGNS GA C FPF
Sbjct: 365 TYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPF 424
Query: 304 TFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHE 354
+ + Y CTS GR D WC TT NYD D+K+GFCP +AAHE
Sbjct: 425 LYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCP--------MAAHE 467
>gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens]
Length = 2296
Score = 146 bits (368), Expect = 6e-35
Identities = 70/178 (39%), Positives = 97/178 (54%), Gaps = 16/178 (8%)
Query: 167 EGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPH 226
E V + GN++GE C PF +NG+ + SCT GR DG LWCSTT N+E+D KY FC
Sbjct: 344 ETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTD 403
Query: 227 EALF--TMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE 284
+ T GGN+ G C FPF + +Y CT+EGR D +WCGTT++YD D+K+GFCP
Sbjct: 404 HTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPM 463
Query: 285 TAMSTVGGNSEGAPCVFPFTFLGNKYES---------CTSAGRSDGKMWCATTANYDD 333
A + +EG +G++++ CT G G+ C + D
Sbjct: 464 AAHEEICTTNEGV-----MYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRD 516
Score = 145 bits (365), Expect = 1e-34
Identities = 77/171 (45%), Positives = 97/171 (56%), Gaps = 18/171 (10%)
Query: 194 YNSC-TDTG--RSDGFLWCSTTYNFEKD----GKYGFCPHEALF-TMGGNAEGQPCKFPF 245
Y C TD+G S G W T N + G C A+ T GGN+ G+PC PF
Sbjct: 305 YGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPF 364
Query: 246 RFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE--TAMSTVGGNSEGAPCVFPF 303
+ G ++ SCTTEGR DG+ WC TT +Y++D+KY FC + + T GGNS GA C FPF
Sbjct: 365 TYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPF 424
Query: 304 TFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHE 354
+ + Y CTS GR D WC TT NYD D+K+GFCP +AAHE
Sbjct: 425 LYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCP--------MAAHE 467
>gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens]
Length = 2421
Score = 146 bits (368), Expect = 6e-35
Identities = 70/178 (39%), Positives = 97/178 (54%), Gaps = 16/178 (8%)
Query: 167 EGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPH 226
E V + GN++GE C PF +NG+ + SCT GR DG LWCSTT N+E+D KY FC
Sbjct: 344 ETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTD 403
Query: 227 EALF--TMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE 284
+ T GGN+ G C FPF + +Y CT+EGR D +WCGTT++YD D+K+GFCP
Sbjct: 404 HTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPM 463
Query: 285 TAMSTVGGNSEGAPCVFPFTFLGNKYES---------CTSAGRSDGKMWCATTANYDD 333
A + +EG +G++++ CT G G+ C + D
Sbjct: 464 AAHEEICTTNEGV-----MYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRD 516
Score = 145 bits (365), Expect = 1e-34
Identities = 77/171 (45%), Positives = 97/171 (56%), Gaps = 18/171 (10%)
Query: 194 YNSC-TDTG--RSDGFLWCSTTYNFEKD----GKYGFCPHEALF-TMGGNAEGQPCKFPF 245
Y C TD+G S G W T N + G C A+ T GGN+ G+PC PF
Sbjct: 305 YGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPF 364
Query: 246 RFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE--TAMSTVGGNSEGAPCVFPF 303
+ G ++ SCTTEGR DG+ WC TT +Y++D+KY FC + + T GGNS GA C FPF
Sbjct: 365 TYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPF 424
Query: 304 TFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHE 354
+ + Y CTS GR D WC TT NYD D+K+GFCP +AAHE
Sbjct: 425 LYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCP--------MAAHE 467
>gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens]
Length = 2176
Score = 146 bits (368), Expect = 6e-35
Identities = 70/178 (39%), Positives = 97/178 (54%), Gaps = 16/178 (8%)
Query: 167 EGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPH 226
E V + GN++GE C PF +NG+ + SCT GR DG LWCSTT N+E+D KY FC
Sbjct: 344 ETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTD 403
Query: 227 EALF--TMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE 284
+ T GGN+ G C FPF + +Y CT+EGR D +WCGTT++YD D+K+GFCP
Sbjct: 404 HTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPM 463
Query: 285 TAMSTVGGNSEGAPCVFPFTFLGNKYES---------CTSAGRSDGKMWCATTANYDD 333
A + +EG +G++++ CT G G+ C + D
Sbjct: 464 AAHEEICTTNEGV-----MYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRD 516
Score = 145 bits (365), Expect = 1e-34
Identities = 77/171 (45%), Positives = 97/171 (56%), Gaps = 18/171 (10%)
Query: 194 YNSC-TDTG--RSDGFLWCSTTYNFEKD----GKYGFCPHEALF-TMGGNAEGQPCKFPF 245
Y C TD+G S G W T N + G C A+ T GGN+ G+PC PF
Sbjct: 305 YGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPF 364
Query: 246 RFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE--TAMSTVGGNSEGAPCVFPF 303
+ G ++ SCTTEGR DG+ WC TT +Y++D+KY FC + + T GGNS GA C FPF
Sbjct: 365 TYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPF 424
Query: 304 TFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHE 354
+ + Y CTS GR D WC TT NYD D+K+GFCP +AAHE
Sbjct: 425 LYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCP--------MAAHE 467
>gi|47132547 fibronectin 1 isoform 7 preproprotein [Homo sapiens]
Length = 657
Score = 146 bits (368), Expect = 6e-35
Identities = 70/178 (39%), Positives = 97/178 (54%), Gaps = 16/178 (8%)
Query: 167 EGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPH 226
E V + GN++GE C PF +NG+ + SCT GR DG LWCSTT N+E+D KY FC
Sbjct: 344 ETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTD 403
Query: 227 EALF--TMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE 284
+ T GGN+ G C FPF + +Y CT+EGR D +WCGTT++YD D+K+GFCP
Sbjct: 404 HTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPM 463
Query: 285 TAMSTVGGNSEGAPCVFPFTFLGNKYES---------CTSAGRSDGKMWCATTANYDD 333
A + +EG +G++++ CT G G+ C + D
Sbjct: 464 AAHEEICTTNEGV-----MYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRD 516
Score = 145 bits (365), Expect = 1e-34
Identities = 77/171 (45%), Positives = 97/171 (56%), Gaps = 18/171 (10%)
Query: 194 YNSC-TDTG--RSDGFLWCSTTYNFEKD----GKYGFCPHEALF-TMGGNAEGQPCKFPF 245
Y C TD+G S G W T N + G C A+ T GGN+ G+PC PF
Sbjct: 305 YGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPF 364
Query: 246 RFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE--TAMSTVGGNSEGAPCVFPF 303
+ G ++ SCTTEGR DG+ WC TT +Y++D+KY FC + + T GGNS GA C FPF
Sbjct: 365 TYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPF 424
Query: 304 TFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHE 354
+ + Y CTS GR D WC TT NYD D+K+GFCP +AAHE
Sbjct: 425 LYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCP--------MAAHE 467
>gi|149999365 matrix metalloproteinase 16 isoform 2 preproprotein
[Homo sapiens]
Length = 457
Score = 137 bits (344), Expect = 4e-32
Identities = 77/164 (46%), Positives = 97/164 (59%), Gaps = 18/164 (10%)
Query: 20 LKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVA--NYNFFPRKP-------KWD 70
++ L MQ+F+G+ TG +D+NTI+ M+KPRCG PD + F R+ KW
Sbjct: 69 MQSALAAMQQFYGINMTGKVDRNTIDWMKKPRCGVPDQTRGSSKFHIRRKRYALTGQKWQ 128
Query: 71 KNQITYRIIGYTPDL-DPETVDDAFARAFQVWSDVTPLRF-----SRIHDG--EADIMIN 122
ITY I TP + DPET A RAF VW +VTPL F S + +G + DI I
Sbjct: 129 HKHITYSIKNVTPKVGDPET-RKAIRRAFDVWQNVTPLTFEEVPYSELENGKRDVDITII 187
Query: 123 FGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLG 166
F HGD PFDG+ G LAHA+ PG G+GGD+HFD DE WTLG
Sbjct: 188 FASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLG 231
Score = 116 bits (291), Expect = 5e-26
Identities = 71/179 (39%), Positives = 89/179 (49%), Gaps = 35/179 (19%)
Query: 330 NYDDDRKW--GFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTY--TKNFRLSQ 385
++D D W G G LFLVA HE GHA+GLEHS DP A+MAP Y Y T NF+L
Sbjct: 221 HFDSDEPWTLGNPNHDGNDLFLVAVHELGHALGLEHSNDPTAIMAPFYQYMETDNFKLPN 280
Query: 386 DDIKGIQELYGASPDIDLGTGPTPTLGP-----------------------------VTP 416
DD++GIQ++YG I T P PT+ P P
Sbjct: 281 DDLQGIQKIYGPPDKIPPPTRPLPTVPPHRSIPPADPRKNDRPKPPRPPTGRPSYPGAKP 340
Query: 417 EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYE 475
IC D F+ +A +R E+F FKD++ WR R P+ + FW LP IDAVYE
Sbjct: 341 NIC--DGNFNTLAILRREMFVFKDQWFWRVRNNRVMDGYPMQITYFWRGLPPSIDAVYE 397
Score = 33.1 bits (74), Expect = 0.77
Identities = 16/54 (29%), Positives = 27/54 (50%), Gaps = 2/54 (3%)
Query: 528 KKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYF 581
++ ++F FWR + MD G+P I W +P ++DAV + G +F
Sbjct: 355 REMFVFKDQWFWRVRN-NRVMD-GYPMQITYFWRGLPPSIDAVYENSDGNFVFF 406
>gi|73808266 matrix metalloproteinase 26 preproprotein [Homo
sapiens]
Length = 261
Score = 132 bits (331), Expect = 1e-30
Identities = 64/165 (38%), Positives = 97/165 (58%), Gaps = 2/165 (1%)
Query: 3 YLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNF 62
Y + F+ KES L ++T ++ + F T LD + +P CG PD ++ +
Sbjct: 35 YFHQFFLTKKESPLL--TQETQTQLLQQFHRNGTDLLDMQMHALLHQPHCGVPDGSDTSI 92
Query: 63 FPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMIN 122
P + KW+K+ +TYRII Y D+ P V D+ A +WS+VTPL F ++ +G+ADI ++
Sbjct: 93 SPGRCKWNKHTLTYRIINYPHDMKPSAVKDSIYNAVSIWSNVTPLIFQQVQNGDADIKVS 152
Query: 123 FGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGE 167
F +W H DG+PFDG G+L HAF P +G G HFD +E W+ +
Sbjct: 153 FWQWAHEDGWPFDGPGGILGHAFLPNSGNPGVVHFDKNEHWSASD 197
Score = 69.7 bits (169), Expect = 7e-12
Identities = 34/76 (44%), Positives = 48/76 (63%), Gaps = 3/76 (3%)
Query: 330 NYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTY--TKNFRLSQDD 387
++D + W D GY+LFLVA HE GH++GL+HS + ++M P Y Y + F+LS DD
Sbjct: 186 HFDKNEHWS-ASDTGYNLFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHDPRTFQLSADD 244
Query: 388 IKGIQELYGASPDIDL 403
I+ IQ LYG D+
Sbjct: 245 IQRIQHLYGEKCSSDI 260
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.140 0.462
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,480,498
Number of Sequences: 37866
Number of extensions: 1389635
Number of successful extensions: 2690
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 67
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2256
Number of HSP's gapped (non-prelim): 181
length of query: 610
length of database: 18,247,518
effective HSP length: 108
effective length of query: 502
effective length of database: 14,157,990
effective search space: 7107310980
effective search space used: 7107310980
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.