Guide to the Human Genome
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Search of human proteins with 18640750

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18640750 regulator of G-protein signalling 18 [Homo sapiens]
         (235 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18640750 regulator of G-protein signalling 18 [Homo sapiens]       473   e-134
gi|4506519 regulator of G-protein signalling 5 [Homo sapiens]         166   2e-41
gi|4506517 regulator of G-protein signaling 2, 24kDa [Homo sapiens]   164   5e-41
gi|5032039 regulator of G-protein signaling 4 isoform 2 [Homo sa...   159   2e-39
gi|156416012 regulator of G-protein signaling 4 isoform 1 [Homo ...   159   2e-39
gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo...   159   2e-39
gi|10864075 regulator of G-protein signalling 3 isoform 2 [Homo ...   159   2e-39
gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo ...   159   2e-39
gi|16117777 regulator of G-protein signalling 8 isoform 1 [Homo ...   158   4e-39
gi|62865656 regulator of G-protein signalling 3 isoform 5 [Homo ...   157   6e-39
gi|156416024 regulator of G-protein signalling 8 isoform 2 [Homo...   157   6e-39
gi|164664488 regulator of G-protein signaling 4 isoform 3 [Homo ...   155   3e-38
gi|19913392 regulator of G-protein signalling 3 isoform 4 [Homo ...   153   1e-37
gi|85540441 regulator of G-protein signaling 21 [Homo sapiens]        151   5e-37
gi|156416009 regulator of G-protein signalling 16 [Homo sapiens]      147   6e-36
gi|115387108 regulator of G-protein signalling 1 [Homo sapiens]       138   4e-33
gi|13654235 regulator of G-protein signaling 20 isoform b [Homo ...   128   5e-30
gi|41281805 regulator of G-protein signaling 20 isoform a [Homo ...   128   5e-30
gi|21361405 regulator of G-protein signalling 17 [Homo sapiens]       122   2e-28
gi|86990435 G protein signalling regulator 19 [Homo sapiens]          122   3e-28
gi|5031705 G protein signalling regulator 19 [Homo sapiens]           122   3e-28
gi|4506511 regulator of G-protein signalling 13 [Homo sapiens]        114   7e-26
gi|21464139 regulator of G-protein signalling 13 [Homo sapiens]       114   7e-26
gi|52694755 regulator of G-protein signaling 10 isoform a [Homo ...   111   6e-25
gi|31742476 regulator of G-protein signalling 6 [Homo sapiens]        108   3e-24
gi|4506505 regulator of G-protein signaling 10 isoform b [Homo s...   108   3e-24
gi|156627563 regulator of G-protein signaling 7 [Homo sapiens]        104   6e-23
gi|126366080 regulator of G-protein signaling 9 isoform 2 [Homo ...    98   7e-21
gi|126365761 regulator of G-protein signaling 9 isoform 1 [Homo ...    98   7e-21
gi|34452688 regulator of G-protein signalling 11 isoform 1 [Homo...    95   5e-20

>gi|18640750 regulator of G-protein signalling 18 [Homo sapiens]
          Length = 235

 Score =  473 bits (1218), Expect = e-134
 Identities = 235/235 (100%), Positives = 235/235 (100%)

Query: 1   METTLLFFSQINMCESKEKTFFKLIHGSGKEETSKEAKIRAKEKRNRLSLLVQKPEFHED 60
           METTLLFFSQINMCESKEKTFFKLIHGSGKEETSKEAKIRAKEKRNRLSLLVQKPEFHED
Sbjct: 1   METTLLFFSQINMCESKEKTFFKLIHGSGKEETSKEAKIRAKEKRNRLSLLVQKPEFHED 60

Query: 61  TRSSRSGHLAKETRVSPEEAVKWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACE 120
           TRSSRSGHLAKETRVSPEEAVKWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACE
Sbjct: 61  TRSSRSGHLAKETRVSPEEAVKWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACE 120

Query: 121 DFKKSKGPQQIHLKAKAIYEKFIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRV 180
           DFKKSKGPQQIHLKAKAIYEKFIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRV
Sbjct: 121 DFKKSKGPQQIHLKAKAIYEKFIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRV 180

Query: 181 YQLMEQDSYTRFLKSDIYLDLMEGRPQRPTNLRRRSRSFTCNEFQDVQSDVAIWL 235
           YQLMEQDSYTRFLKSDIYLDLMEGRPQRPTNLRRRSRSFTCNEFQDVQSDVAIWL
Sbjct: 181 YQLMEQDSYTRFLKSDIYLDLMEGRPQRPTNLRRRSRSFTCNEFQDVQSDVAIWL 235


>gi|4506519 regulator of G-protein signalling 5 [Homo sapiens]
          Length = 181

 Score =  166 bits (419), Expect = 2e-41
 Identities = 82/167 (49%), Positives = 119/167 (71%), Gaps = 3/167 (1%)

Query: 40  RAKEKRNRLSLLVQKPEFHEDT---RSSRSGHLAKETRVSPEEAVKWGESFDKLLSHRDG 96
           RAKE + +L +L+QKP+   D     + +    AK  + S +EA++W +S DKLL +  G
Sbjct: 15  RAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQWRDSLDKLLQNNYG 74

Query: 97  LEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEKFIQTDAPKEVNLDFH 156
           L +F  FLK+EFSEEN+EFWIACED+KK K P ++  KAK IYE+FIQT+APKEVN+D  
Sbjct: 75  LASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHF 134

Query: 157 TKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDLME 203
           TK++   ++ +P+L SFD AQ R++ LME+DS  RF++S+ Y +L++
Sbjct: 135 TKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELIK 181


>gi|4506517 regulator of G-protein signaling 2, 24kDa [Homo sapiens]
          Length = 211

 Score =  164 bits (416), Expect = 5e-41
 Identities = 86/187 (45%), Positives = 118/187 (63%), Gaps = 4/187 (2%)

Query: 27  GSGKEETSKEAKIRA---KEKRNRLSLLVQKPEFHEDTRSSRSGHLAKETRVSPEEAVKW 83
           GSG +   K  K++    K+ + RLS  +Q        ++ +        + SPEEA  W
Sbjct: 21  GSGHKSEEKREKMKRTLLKDWKTRLSYFLQNSSTPGKPKTGKKSKQQAFIKPSPEEAQLW 80

Query: 84  GESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEKFI 143
            E+FD+LL+ + GL AF  FLK+EF EENIEFW+ACEDFKK+K PQ++  KA+ IY  FI
Sbjct: 81  SEAFDELLASKYGLAAFRAFLKSEFCEENIEFWLACEDFKKTKSPQKLSSKARKIYTDFI 140

Query: 144 QTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDLME 203
           + +APKE+N+DF TK +I  +I + T   F  AQ RVY LME +SY RFL+S+ Y DL +
Sbjct: 141 EKEAPKEINIDFQTKTLIAQNIQEATSGCFTTAQKRVYSLMENNSYPRFLESEFYQDLCK 200

Query: 204 GRPQRPT 210
            +PQ  T
Sbjct: 201 -KPQITT 206


>gi|5032039 regulator of G-protein signaling 4 isoform 2 [Homo
           sapiens]
          Length = 205

 Score =  159 bits (402), Expect = 2e-39
 Identities = 82/167 (49%), Positives = 110/167 (65%), Gaps = 9/167 (5%)

Query: 41  AKEKRNRLSLLVQKPEFHEDTRSSRSGHLAKET-----RVSPEEAVKWGESFDKLLSHRD 95
           AK+ ++RL  L+QK     D+    S H  K+      RVS EE  KW ES + L+SH  
Sbjct: 16  AKDMKHRLGFLLQK----SDSCEHNSSHNKKDKVVICQRVSQEEVKKWAESLENLISHEC 71

Query: 96  GLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEKFIQTDAPKEVNLDF 155
           GL AF  FLK+E+SEENI+FWI+CE++KK K P ++  KAK IY +FI   A KEVNLD 
Sbjct: 72  GLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDS 131

Query: 156 HTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDLM 202
            T+E  + ++ +PT+  FD AQ +++ LME+DSY RFLKS  YLDL+
Sbjct: 132 CTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLV 178


>gi|156416012 regulator of G-protein signaling 4 isoform 1 [Homo
           sapiens]
          Length = 302

 Score =  159 bits (402), Expect = 2e-39
 Identities = 82/167 (49%), Positives = 110/167 (65%), Gaps = 9/167 (5%)

Query: 41  AKEKRNRLSLLVQKPEFHEDTRSSRSGHLAKET-----RVSPEEAVKWGESFDKLLSHRD 95
           AK+ ++RL  L+QK     D+    S H  K+      RVS EE  KW ES + L+SH  
Sbjct: 113 AKDMKHRLGFLLQK----SDSCEHNSSHNKKDKVVICQRVSQEEVKKWAESLENLISHEC 168

Query: 96  GLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEKFIQTDAPKEVNLDF 155
           GL AF  FLK+E+SEENI+FWI+CE++KK K P ++  KAK IY +FI   A KEVNLD 
Sbjct: 169 GLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDS 228

Query: 156 HTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDLM 202
            T+E  + ++ +PT+  FD AQ +++ LME+DSY RFLKS  YLDL+
Sbjct: 229 CTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLV 275


>gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo
            sapiens]
          Length = 1198

 Score =  159 bits (402), Expect = 2e-39
 Identities = 80/181 (44%), Positives = 119/181 (65%), Gaps = 2/181 (1%)

Query: 31   EETSKEAKIR--AKEKRNRLSLLVQKPEFHEDTRSSRSGHLAKETRVSPEEAVKWGESFD 88
            +E S++ K +  AK+ +N+L +  ++ E      + ++  + K  + + EEA+KWGES +
Sbjct: 1016 DEASRKRKSKNLAKDMKNKLGIFRRRNESPGAPPAGKADKMMKSFKPTSEEALKWGESLE 1075

Query: 89   KLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEKFIQTDAP 148
            KLL H+ GL  F  FL+TEFSEEN+EFW+ACEDFKK K   ++  KAK I+ ++I   A 
Sbjct: 1076 KLLVHKYGLAVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMASKAKKIFAEYIAIQAC 1135

Query: 149  KEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDLMEGRPQR 208
            KEVNLD +T+E   +++   T   FD AQ R++ LME+DSY RFL+SD+YLDL+  +   
Sbjct: 1136 KEVNLDSYTREHTKDNLQSVTRGCFDLAQKRIFGLMEKDSYPRFLRSDLYLDLINQKKMS 1195

Query: 209  P 209
            P
Sbjct: 1196 P 1196


>gi|10864075 regulator of G-protein signalling 3 isoform 2 [Homo
           sapiens]
          Length = 519

 Score =  159 bits (402), Expect = 2e-39
 Identities = 80/181 (44%), Positives = 119/181 (65%), Gaps = 2/181 (1%)

Query: 31  EETSKEAKIR--AKEKRNRLSLLVQKPEFHEDTRSSRSGHLAKETRVSPEEAVKWGESFD 88
           +E S++ K +  AK+ +N+L +  ++ E      + ++  + K  + + EEA+KWGES +
Sbjct: 337 DEASRKRKSKNLAKDMKNKLGIFRRRNESPGAPPAGKADKMMKSFKPTSEEALKWGESLE 396

Query: 89  KLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEKFIQTDAP 148
           KLL H+ GL  F  FL+TEFSEEN+EFW+ACEDFKK K   ++  KAK I+ ++I   A 
Sbjct: 397 KLLVHKYGLAVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMASKAKKIFAEYIAIQAC 456

Query: 149 KEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDLMEGRPQR 208
           KEVNLD +T+E   +++   T   FD AQ R++ LME+DSY RFL+SD+YLDL+  +   
Sbjct: 457 KEVNLDSYTREHTKDNLQSVTRGCFDLAQKRIFGLMEKDSYPRFLRSDLYLDLINQKKMS 516

Query: 209 P 209
           P
Sbjct: 517 P 517


>gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo
           sapiens]
          Length = 917

 Score =  159 bits (402), Expect = 2e-39
 Identities = 80/181 (44%), Positives = 119/181 (65%), Gaps = 2/181 (1%)

Query: 31  EETSKEAKIR--AKEKRNRLSLLVQKPEFHEDTRSSRSGHLAKETRVSPEEAVKWGESFD 88
           +E S++ K +  AK+ +N+L +  ++ E      + ++  + K  + + EEA+KWGES +
Sbjct: 735 DEASRKRKSKNLAKDMKNKLGIFRRRNESPGAPPAGKADKMMKSFKPTSEEALKWGESLE 794

Query: 89  KLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEKFIQTDAP 148
           KLL H+ GL  F  FL+TEFSEEN+EFW+ACEDFKK K   ++  KAK I+ ++I   A 
Sbjct: 795 KLLVHKYGLAVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMASKAKKIFAEYIAIQAC 854

Query: 149 KEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDLMEGRPQR 208
           KEVNLD +T+E   +++   T   FD AQ R++ LME+DSY RFL+SD+YLDL+  +   
Sbjct: 855 KEVNLDSYTREHTKDNLQSVTRGCFDLAQKRIFGLMEKDSYPRFLRSDLYLDLINQKKMS 914

Query: 209 P 209
           P
Sbjct: 915 P 915


>gi|16117777 regulator of G-protein signalling 8 isoform 1 [Homo
           sapiens]
          Length = 198

 Score =  158 bits (399), Expect = 4e-39
 Identities = 82/187 (43%), Positives = 119/187 (63%), Gaps = 6/187 (3%)

Query: 26  HGSGKE-ETSKEAKIRAKEKRNRLSLLVQKPEFHEDTRS---SRSGHLAKETRVSPEEAV 81
           H  GK+ +  +  + + K  R RL  L  K +   D  +    +     K  R+S EEA 
Sbjct: 12  HPVGKDPQAMRTGQRQNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALK--RLSTEEAT 69

Query: 82  KWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEK 141
           +W +SFD LLSH+ G+ AF  FLKTEFSEEN+EFW+ACE+FKK++   ++  KA  I+E+
Sbjct: 70  RWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEE 129

Query: 142 FIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDL 201
           F+   AP+EVN+DF T+E    ++ +P+L  FD AQ +V+ LME+DSY RFL+S +YLDL
Sbjct: 130 FVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDL 189

Query: 202 MEGRPQR 208
           +    +R
Sbjct: 190 LSQSQRR 196


>gi|62865656 regulator of G-protein signalling 3 isoform 5 [Homo
           sapiens]
          Length = 311

 Score =  157 bits (398), Expect = 6e-39
 Identities = 80/180 (44%), Positives = 116/180 (64%), Gaps = 4/180 (2%)

Query: 30  KEETSKEAKIRAKEKRNRLSLLVQKPEFHEDTRSSRSGHLAKETRVSPEEAVKWGESFDK 89
           +  T KEAK    + +N+L +  ++ E      + ++  + K  + + EEA+KWGES +K
Sbjct: 134 RRHTMKEAK----DMKNKLGIFRRRNESPGAPPAGKADKMMKSFKPTSEEALKWGESLEK 189

Query: 90  LLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEKFIQTDAPK 149
           LL H+ GL  F  FL+TEFSEEN+EFW+ACEDFKK K   ++  KAK I+ ++I   A K
Sbjct: 190 LLVHKYGLAVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMASKAKKIFAEYIAIQACK 249

Query: 150 EVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDLMEGRPQRP 209
           EVNLD +T+E   +++   T   FD AQ R++ LME+DSY RFL+SD+YLDL+  +   P
Sbjct: 250 EVNLDSYTREHTKDNLQSVTRGCFDLAQKRIFGLMEKDSYPRFLRSDLYLDLINQKKMSP 309


>gi|156416024 regulator of G-protein signalling 8 isoform 2 [Homo
           sapiens]
          Length = 180

 Score =  157 bits (398), Expect = 6e-39
 Identities = 80/172 (46%), Positives = 112/172 (65%), Gaps = 5/172 (2%)

Query: 40  RAKEKRNRLSLLVQKPEFHEDTRS---SRSGHLAKETRVSPEEAVKWGESFDKLLSHRDG 96
           R K  R RL  L  K +   D  +    +     K  R+S EEA +W +SFD LLSH+ G
Sbjct: 9   RNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALK--RLSTEEATRWADSFDVLLSHKYG 66

Query: 97  LEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEKFIQTDAPKEVNLDFH 156
           + AF  FLKTEFSEEN+EFW+ACE+FKK++   ++  KA  I+E+F+   AP+EVN+DF 
Sbjct: 67  VAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQ 126

Query: 157 TKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDLMEGRPQR 208
           T+E    ++ +P+L  FD AQ +V+ LME+DSY RFL+S +YLDL+    +R
Sbjct: 127 TREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRR 178


>gi|164664488 regulator of G-protein signaling 4 isoform 3 [Homo
           sapiens]
          Length = 187

 Score =  155 bits (392), Expect = 3e-38
 Identities = 80/163 (49%), Positives = 107/163 (65%), Gaps = 9/163 (5%)

Query: 45  RNRLSLLVQKPEFHEDTRSSRSGHLAKET-----RVSPEEAVKWGESFDKLLSHRDGLEA 99
           ++RL  L+QK     D+    S H  K+      RVS EE  KW ES + L+SH  GL A
Sbjct: 2   KHRLGFLLQK----SDSCEHNSSHNKKDKVVICQRVSQEEVKKWAESLENLISHECGLAA 57

Query: 100 FTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEKFIQTDAPKEVNLDFHTKE 159
           F  FLK+E+SEENI+FWI+CE++KK K P ++  KAK IY +FI   A KEVNLD  T+E
Sbjct: 58  FKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTRE 117

Query: 160 VITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDLM 202
             + ++ +PT+  FD AQ +++ LME+DSY RFLKS  YLDL+
Sbjct: 118 ETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLV 160


>gi|19913392 regulator of G-protein signalling 3 isoform 4 [Homo
           sapiens]
          Length = 168

 Score =  153 bits (387), Expect = 1e-37
 Identities = 75/165 (45%), Positives = 109/165 (66%)

Query: 45  RNRLSLLVQKPEFHEDTRSSRSGHLAKETRVSPEEAVKWGESFDKLLSHRDGLEAFTRFL 104
           +N+L +  ++ E      + ++  + K  + + EEA+KWGES +KLL H+ GL  F  FL
Sbjct: 2   KNKLGIFRRRNESPGAPPAGKADKMMKSFKPTSEEALKWGESLEKLLVHKYGLAVFQAFL 61

Query: 105 KTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEKFIQTDAPKEVNLDFHTKEVITNS 164
           +TEFSEEN+EFW+ACEDFKK K   ++  KAK I+ ++I   A KEVNLD +T+E   ++
Sbjct: 62  RTEFSEENLEFWLACEDFKKVKSQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDN 121

Query: 165 ITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDLMEGRPQRP 209
           +   T   FD AQ R++ LME+DSY RFL+SD+YLDL+  +   P
Sbjct: 122 LQSVTRGCFDLAQKRIFGLMEKDSYPRFLRSDLYLDLINQKKMSP 166


>gi|85540441 regulator of G-protein signaling 21 [Homo sapiens]
          Length = 152

 Score =  151 bits (381), Expect = 5e-37
 Identities = 69/127 (54%), Positives = 96/127 (75%)

Query: 79  EAVKWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAI 138
           E + W E+ D LL+++ GL+AF  FLK+EFSEEN+EFW+ACEDFKK+K   +I  KAK I
Sbjct: 14  ETMTWSENMDTLLANQAGLDAFRIFLKSEFSEENVEFWLACEDFKKTKNADKIASKAKMI 73

Query: 139 YEKFIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIY 198
           Y +FI+ DAPKE+N+DF T+++I+ +I +PTL  FD AQ  +Y LM +DS+ RFLKS+IY
Sbjct: 74  YSEFIEADAPKEINIDFGTRDLISKNIAEPTLKCFDEAQKLIYCLMAKDSFPRFLKSEIY 133

Query: 199 LDLMEGR 205
             L+  +
Sbjct: 134 KKLVNSQ 140


>gi|156416009 regulator of G-protein signalling 16 [Homo sapiens]
          Length = 202

 Score =  147 bits (372), Expect = 6e-36
 Identities = 81/167 (48%), Positives = 108/167 (64%), Gaps = 6/167 (3%)

Query: 40  RAKEKRNRLSLLVQKPEFHEDTRSSR-----SGHLAKETRVSPEEAVKWGESFDKLLSHR 94
           RAKE + RL + + K E   DT S+      S H +KE R   E+ + W ESFD LLS +
Sbjct: 15  RAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKH-SKENRNFSEDVLGWRESFDLLLSSK 73

Query: 95  DGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEKFIQTDAPKEVNLD 154
           +G+ AF  FLKTEFSEEN+EFW+ACE+FKK +   ++  +A  I+E+FI ++APKEVN+D
Sbjct: 74  NGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNID 133

Query: 155 FHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDL 201
             T E+   ++   T   FDAAQ +   LME+DSY RFLKS  Y DL
Sbjct: 134 HETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDL 180


>gi|115387108 regulator of G-protein signalling 1 [Homo sapiens]
          Length = 209

 Score =  138 bits (348), Expect = 4e-33
 Identities = 69/148 (46%), Positives = 98/148 (66%), Gaps = 6/148 (4%)

Query: 55  PEFHEDTRSSRSGHLAKETRVSPEEAVKWGESFDKLLSHRDGLEAFTRFLKTEFSEENIE 114
           P      +SS+S  +     +S  E ++W +S +KLL+++ G   F  FLK+EFSEENIE
Sbjct: 59  PHLESGMKSSKSKDV-----LSAAEVMQWSQSLEKLLANQTGQNVFGSFLKSEFSEENIE 113

Query: 115 FWIACEDFKKSKGPQQIHLKAKAIYEKFIQTDAPKEVNLDFHTKEVITNSITQPTLHSFD 174
           FW+ACED+KK++    +  KA+ IY+ F+ +DA K++N+DF T+E     I  PT   FD
Sbjct: 114 FWLACEDYKKTES-DLLPCKAEEIYKAFVHSDAAKQINIDFRTRESTAKKIKAPTPTCFD 172

Query: 175 AAQSRVYQLMEQDSYTRFLKSDIYLDLM 202
            AQ  +Y LME+DSY RFLKSDIYL+L+
Sbjct: 173 EAQKVIYTLMEKDSYPRFLKSDIYLNLL 200


>gi|13654235 regulator of G-protein signaling 20 isoform b [Homo
           sapiens]
          Length = 241

 Score =  128 bits (321), Expect = 5e-30
 Identities = 61/131 (46%), Positives = 85/131 (64%)

Query: 78  EEAVKWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKA 137
           EE   W +SFDKL+    G  AF  FL+TEFSEEN+ FW+ACE+ KK      I  KA+ 
Sbjct: 107 EEVNAWAQSFDKLMVTPAGRNAFREFLRTEFSEENMLFWMACEELKKEANKNIIEEKARI 166

Query: 138 IYEKFIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDI 197
           IYE +I   +PKEV+LD   +EVI  ++ +P+ H FD AQ ++Y LM +DSY RF+ S +
Sbjct: 167 IYEDYISILSPKEVSLDSRVREVINRNMVEPSQHIFDDAQLQIYTLMHRDSYPRFMNSAV 226

Query: 198 YLDLMEGRPQR 208
           Y DL++   ++
Sbjct: 227 YKDLLQSLSEK 237


>gi|41281805 regulator of G-protein signaling 20 isoform a [Homo
           sapiens]
          Length = 388

 Score =  128 bits (321), Expect = 5e-30
 Identities = 61/131 (46%), Positives = 85/131 (64%)

Query: 78  EEAVKWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKA 137
           EE   W +SFDKL+    G  AF  FL+TEFSEEN+ FW+ACE+ KK      I  KA+ 
Sbjct: 254 EEVNAWAQSFDKLMVTPAGRNAFREFLRTEFSEENMLFWMACEELKKEANKNIIEEKARI 313

Query: 138 IYEKFIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDI 197
           IYE +I   +PKEV+LD   +EVI  ++ +P+ H FD AQ ++Y LM +DSY RF+ S +
Sbjct: 314 IYEDYISILSPKEVSLDSRVREVINRNMVEPSQHIFDDAQLQIYTLMHRDSYPRFMNSAV 373

Query: 198 YLDLMEGRPQR 208
           Y DL++   ++
Sbjct: 374 YKDLLQSLSEK 384


>gi|21361405 regulator of G-protein signalling 17 [Homo sapiens]
          Length = 210

 Score =  122 bits (307), Expect = 2e-28
 Identities = 56/126 (44%), Positives = 81/126 (64%)

Query: 78  EEAVKWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKA 137
           EE + W ++FDK++    G   F  FL+TE+SEEN+ FW+ACED KK +  + I  KA+ 
Sbjct: 76  EEVLSWSQNFDKMMKAPAGRNLFREFLRTEYSEENLLFWLACEDLKKEQNKKVIEEKARM 135

Query: 138 IYEKFIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDI 197
           IYE +I   +PKEV+LD   +EVI  ++  P  H ++ AQ ++Y LM +DS+ RFL S I
Sbjct: 136 IYEDYISILSPKEVSLDSRVREVINRNLLDPNPHMYEDAQLQIYTLMHRDSFPRFLNSQI 195

Query: 198 YLDLME 203
           Y   +E
Sbjct: 196 YKSFVE 201


>gi|86990435 G protein signalling regulator 19 [Homo sapiens]
          Length = 217

 Score =  122 bits (306), Expect = 3e-28
 Identities = 58/136 (42%), Positives = 83/136 (61%)

Query: 76  SPEEAVKWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKA 135
           SPEE   W +SFDKL+    G   F  FL+TE+SEEN+ FW+ACE+ K       +  KA
Sbjct: 80  SPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFWLACEELKAEANQHVVDEKA 139

Query: 136 KAIYEKFIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKS 195
           + IYE ++   +PKEV+LD   +E I   + +P+ H+FD AQ ++Y LM +DSY RFL S
Sbjct: 140 RLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDAQLQIYTLMHRDSYPRFLSS 199

Query: 196 DIYLDLMEGRPQRPTN 211
             Y  L+   P + ++
Sbjct: 200 PTYRALLLQGPSQSSS 215


>gi|5031705 G protein signalling regulator 19 [Homo sapiens]
          Length = 217

 Score =  122 bits (306), Expect = 3e-28
 Identities = 58/136 (42%), Positives = 83/136 (61%)

Query: 76  SPEEAVKWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKA 135
           SPEE   W +SFDKL+    G   F  FL+TE+SEEN+ FW+ACE+ K       +  KA
Sbjct: 80  SPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFWLACEELKAEANQHVVDEKA 139

Query: 136 KAIYEKFIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKS 195
           + IYE ++   +PKEV+LD   +E I   + +P+ H+FD AQ ++Y LM +DSY RFL S
Sbjct: 140 RLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDAQLQIYTLMHRDSYPRFLSS 199

Query: 196 DIYLDLMEGRPQRPTN 211
             Y  L+   P + ++
Sbjct: 200 PTYRALLLQGPSQSSS 215


>gi|4506511 regulator of G-protein signalling 13 [Homo sapiens]
          Length = 159

 Score =  114 bits (285), Expect = 7e-26
 Identities = 53/126 (42%), Positives = 83/126 (65%)

Query: 78  EEAVKWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKA 137
           EE ++W +SF+ L++ + G   +  +LK E S+ENI+FW+ACE +KK         +AK 
Sbjct: 26  EEVLQWAQSFENLMATKYGPVVYAAYLKMEHSDENIQFWMACETYKKIASRWSRISRAKK 85

Query: 138 IYEKFIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDI 197
           +Y+ +IQ  +P+E+N+D  T+E I  +I +PT   F+ AQ  VY  ME+DSY RFLKS++
Sbjct: 86  LYKIYIQPQSPREINIDSSTRETIIRNIQEPTETCFEEAQKIVYMHMERDSYPRFLKSEM 145

Query: 198 YLDLME 203
           Y  L++
Sbjct: 146 YQKLLK 151


>gi|21464139 regulator of G-protein signalling 13 [Homo sapiens]
          Length = 159

 Score =  114 bits (285), Expect = 7e-26
 Identities = 53/126 (42%), Positives = 83/126 (65%)

Query: 78  EEAVKWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKA 137
           EE ++W +SF+ L++ + G   +  +LK E S+ENI+FW+ACE +KK         +AK 
Sbjct: 26  EEVLQWAQSFENLMATKYGPVVYAAYLKMEHSDENIQFWMACETYKKIASRWSRISRAKK 85

Query: 138 IYEKFIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDI 197
           +Y+ +IQ  +P+E+N+D  T+E I  +I +PT   F+ AQ  VY  ME+DSY RFLKS++
Sbjct: 86  LYKIYIQPQSPREINIDSSTRETIIRNIQEPTETCFEEAQKIVYMHMERDSYPRFLKSEM 145

Query: 198 YLDLME 203
           Y  L++
Sbjct: 146 YQKLLK 151


>gi|52694755 regulator of G-protein signaling 10 isoform a [Homo
           sapiens]
          Length = 181

 Score =  111 bits (277), Expect = 6e-25
 Identities = 65/180 (36%), Positives = 97/180 (53%), Gaps = 13/180 (7%)

Query: 46  NRLSLLVQKPEFHEDTRSSRSGHLAKETRVSPEEAVKWGESFDKLLSHRDGLEAFTRFLK 105
           +RLS      + H+   SS S H       S +   KW  S + LL   +G++ F  FLK
Sbjct: 7   SRLSRKRPPSDIHDSDGSSSSSHQ------SLKSTAKWAASLENLLEDPEGVKRFREFLK 60

Query: 106 TEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEKFIQTDAPKEVNLDFHTKEVITNSI 165
            EFSEEN+ FW+ACEDFKK +   Q+  KAK IY  F+ + A  +VN++  ++ +    +
Sbjct: 61  KEFSEENVLFWLACEDFKKMQDKTQMQEKAKEIYMTFLSSKASSQVNVEGQSR-LNEKIL 119

Query: 166 TQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYL------DLMEGRPQRPTNLRRRSRSF 219
            +P    F   Q +++ LM+ DSY+RFLKSD++L      +  E  P   T  +R SR +
Sbjct: 120 EEPHPLMFQKLQDQIFNLMKYDSYSRFLKSDLFLKHKRTEEEEEDLPDAQTAAKRASRIY 179


>gi|31742476 regulator of G-protein signalling 6 [Homo sapiens]
          Length = 472

 Score =  108 bits (271), Expect = 3e-24
 Identities = 49/127 (38%), Positives = 82/127 (64%), Gaps = 1/127 (0%)

Query: 76  SPEEAVKWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKA 135
           S +   +WG SFD++L  + G + F RFL++EFS EN+ FW+A +D KK    Q +  + 
Sbjct: 326 SQQRVKRWGFSFDEILKDQVGRDQFLRFLESEFSSENLRFWLAVQDLKKQP-LQDVAKRV 384

Query: 136 KAIYEKFIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKS 195
           + I+++F+   AP  +NLD H+ E+ + ++     ++F+ AQ  +Y+LM+ DSY RFL+S
Sbjct: 385 EEIWQEFLAPGAPSAINLDSHSYEITSQNVKDGGRYTFEDAQEHIYKLMKSDSYARFLRS 444

Query: 196 DIYLDLM 202
           + Y DL+
Sbjct: 445 NAYQDLL 451


>gi|4506505 regulator of G-protein signaling 10 isoform b [Homo
           sapiens]
          Length = 167

 Score =  108 bits (271), Expect = 3e-24
 Identities = 62/168 (36%), Positives = 92/168 (54%), Gaps = 13/168 (7%)

Query: 58  HEDTRSSRSGHLAKETRVSPEEAVKWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWI 117
           H+   SS S H       S +   KW  S + LL   +G++ F  FLK EFSEEN+ FW+
Sbjct: 5   HDSDGSSSSSHQ------SLKSTAKWAASLENLLEDPEGVKRFREFLKKEFSEENVLFWL 58

Query: 118 ACEDFKKSKGPQQIHLKAKAIYEKFIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQ 177
           ACEDFKK +   Q+  KAK IY  F+ + A  +VN++  ++ +    + +P    F   Q
Sbjct: 59  ACEDFKKMQDKTQMQEKAKEIYMTFLSSKASSQVNVEGQSR-LNEKILEEPHPLMFQKLQ 117

Query: 178 SRVYQLMEQDSYTRFLKSDIYL------DLMEGRPQRPTNLRRRSRSF 219
            +++ LM+ DSY+RFLKSD++L      +  E  P   T  +R SR +
Sbjct: 118 DQIFNLMKYDSYSRFLKSDLFLKHKRTEEEEEDLPDAQTAAKRASRIY 165


>gi|156627563 regulator of G-protein signaling 7 [Homo sapiens]
          Length = 487

 Score =  104 bits (260), Expect = 6e-23
 Identities = 47/141 (33%), Positives = 87/141 (61%), Gaps = 1/141 (0%)

Query: 76  SPEEAVKWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKA 135
           S +   +WG   D+ L    G E F +FL++EFS EN+ FW+A ED KK +  +++  + 
Sbjct: 323 SQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENLRFWLAVEDLKK-RPIKEVPSRV 381

Query: 136 KAIYEKFIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKS 195
           + I+++F+   AP  +NLD  + +  T ++ +P  ++F+ AQ  +Y+LM+ DSY RF++S
Sbjct: 382 QEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFEDAQEHIYKLMKSDSYPRFIRS 441

Query: 196 DIYLDLMEGRPQRPTNLRRRS 216
             Y +L++ + +   ++ RR+
Sbjct: 442 SAYQELLQAKKKSGNSMDRRT 462


>gi|126366080 regulator of G-protein signaling 9 isoform 2 [Homo
           sapiens]
          Length = 671

 Score = 97.8 bits (242), Expect = 7e-21
 Identities = 54/146 (36%), Positives = 81/146 (55%), Gaps = 10/146 (6%)

Query: 82  KWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEK 141
           +W  +F +L+    G ++F  FLK EFS EN+ FW ACED K      ++  KA+ IY+ 
Sbjct: 295 RWAFNFSELIRDPKGRQSFQYFLKKEFSGENLGFWEACEDLKYGD-QSKVKEKAEEIYKL 353

Query: 142 FIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDL 201
           F+   A + +N+D  T ++    +  P  +  DAAQ+ +Y LM++DSY R+LKS IY D+
Sbjct: 354 FLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKDM 413

Query: 202 MEG--RPQRPTN-------LRRRSRS 218
           +     PQ  T        +RR  RS
Sbjct: 414 LAKAIEPQETTKKSSTLPFMRRHLRS 439


>gi|126365761 regulator of G-protein signaling 9 isoform 1 [Homo
           sapiens]
          Length = 674

 Score = 97.8 bits (242), Expect = 7e-21
 Identities = 54/146 (36%), Positives = 81/146 (55%), Gaps = 10/146 (6%)

Query: 82  KWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEK 141
           +W  +F +L+    G ++F  FLK EFS EN+ FW ACED K      ++  KA+ IY+ 
Sbjct: 298 RWAFNFSELIRDPKGRQSFQYFLKKEFSGENLGFWEACEDLKYGD-QSKVKEKAEEIYKL 356

Query: 142 FIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDL 201
           F+   A + +N+D  T ++    +  P  +  DAAQ+ +Y LM++DSY R+LKS IY D+
Sbjct: 357 FLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKDM 416

Query: 202 MEG--RPQRPTN-------LRRRSRS 218
           +     PQ  T        +RR  RS
Sbjct: 417 LAKAIEPQETTKKSSTLPFMRRHLRS 442


>gi|34452688 regulator of G-protein signalling 11 isoform 1 [Homo
           sapiens]
          Length = 467

 Score = 95.1 bits (235), Expect = 5e-20
 Identities = 55/139 (39%), Positives = 74/139 (53%), Gaps = 2/139 (1%)

Query: 82  KWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEK 141
           +WG SF +LL    G   F  FL  EFS EN+ FW ACE+ +      Q+     A+YE+
Sbjct: 299 RWGFSFRELLEDPVGRAHFMDFLGKEFSGENLSFWEACEELRYG-AQAQVPTLVDAVYEQ 357

Query: 142 FIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDL 201
           F+   A   VN+D  T E     + QP  +  D AQ  +Y LM++DSY RFLKSD+Y  L
Sbjct: 358 FLAPGAAHWVNIDSRTMEQTLEGLRQPHRYVLDDAQLHIYMLMKKDSYPRFLKSDMYKAL 417

Query: 202 MEGRPQRPTNLRRRSRSFT 220
           +      P  ++RR   FT
Sbjct: 418 L-AEAGIPLEMKRRVFPFT 435


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.131    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,336,862
Number of Sequences: 37866
Number of extensions: 340222
Number of successful extensions: 1167
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 46
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 1097
Number of HSP's gapped (non-prelim): 67
length of query: 235
length of database: 18,247,518
effective HSP length: 99
effective length of query: 136
effective length of database: 14,498,784
effective search space: 1971834624
effective search space used: 1971834624
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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