Search of human proteins with 18426971

Search of human proteins with 18426971

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18426971 deoxyguanosine kinase isoform b precursor [Homo
sapiens]
         (189 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18426971 deoxyguanosine kinase isoform b precursor [Homo sapi...   376   e-105
gi|18426967 deoxyguanosine kinase isoform a precursor [Homo sapi...   297   3e-81
gi|4503269 deoxycytidine kinase [Homo sapiens]                        118   3e-27
gi|92859641 thymidine kinase 2, mitochondrial [Homo sapiens]           52   2e-07
gi|4758768 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1...    36   0.023
gi|11342678 amyloid beta (A4) precursor protein-binding, family ...    32   0.25 
gi|4557537 developmentally regulated GTP binding protein 2 [Homo...    28   6.1  
gi|122056683 FRAS1 related extracellular matrix 1 [Homo sapiens]       28   6.1  
gi|239754042 PREDICTED: similar to hCG1646049 [Homo sapiens]           27   8.0  
gi|239748572 PREDICTED: similar to hCG1646049 [Homo sapiens]           27   8.0  
gi|169167670 PREDICTED: similar to hCG1646049 [Homo sapiens]           27   8.0  

>gi|18426971 deoxyguanosine kinase isoform b precursor [Homo
           sapiens]
          Length = 189

 Score =  376 bits (965), Expect = e-105
 Identities = 189/189 (100%), Positives = 189/189 (100%)

Query: 1   MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTK 60
           MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTK
Sbjct: 1   MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTK 60

Query: 61  TYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLK 120
           TYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLK
Sbjct: 61  TYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLK 120

Query: 121 VQLEPFPEKLLQARKPVQIFERSVYSDRLHFEALMNIPVLVLDVNDDFSEEVTKQEDLMR 180
           VQLEPFPEKLLQARKPVQIFERSVYSDRLHFEALMNIPVLVLDVNDDFSEEVTKQEDLMR
Sbjct: 121 VQLEPFPEKLLQARKPVQIFERSVYSDRLHFEALMNIPVLVLDVNDDFSEEVTKQEDLMR 180

Query: 181 EVNTFVKNL 189
           EVNTFVKNL
Sbjct: 181 EVNTFVKNL 189


>gi|18426967 deoxyguanosine kinase isoform a precursor [Homo
           sapiens]
          Length = 277

 Score =  297 bits (761), Expect = 3e-81
 Identities = 149/151 (98%), Positives = 149/151 (98%)

Query: 1   MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTK 60
           MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTK
Sbjct: 1   MAAGRLFLSRLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTK 60

Query: 61  TYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLK 120
           TYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLK
Sbjct: 61  TYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLK 120

Query: 121 VQLEPFPEKLLQARKPVQIFERSVYSDRLHF 151
           VQLEPFPEKLLQARKPVQIFERSVYSDR  F
Sbjct: 121 VQLEPFPEKLLQARKPVQIFERSVYSDRYIF 151



 Score = 84.7 bits (208), Expect = 4e-17
 Identities = 41/42 (97%), Positives = 42/42 (100%)

Query: 148 RLHFEALMNIPVLVLDVNDDFSEEVTKQEDLMREVNTFVKNL 189
           +LHFEALMNIPVLVLDVNDDFSEEVTKQEDLMREVNTFVKNL
Sbjct: 236 KLHFEALMNIPVLVLDVNDDFSEEVTKQEDLMREVNTFVKNL 277


>gi|4503269 deoxycytidine kinase [Homo sapiens]
          Length = 260

 Score =  118 bits (296), Expect = 3e-27
 Identities = 63/137 (45%), Positives = 82/137 (59%), Gaps = 3/137 (2%)

Query: 18  MAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTKTYPEWHVATEPVATWQN 77
           MA  P     S      G   +++SIEGNIA GKSTFV +L +   +W V  EPVA W N
Sbjct: 1   MATPPKRSCPSFSASSEGTRIKKISIEGNIAAGKSTFVNILKQLCEDWEVVPEPVARWCN 60

Query: 78  IQAAGTQ---KACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLKVQLEPFPEKLLQAR 134
           +Q+   +      + ++ GN+L MMY +P RWS+TFQT++ LSR++ QL     KL  A 
Sbjct: 61  VQSTQDEFEELTMSQKNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAE 120

Query: 135 KPVQIFERSVYSDRLHF 151
           KPV  FERSVYSDR  F
Sbjct: 121 KPVLFFERSVYSDRYIF 137



 Score = 35.4 bits (80), Expect = 0.029
 Identities = 16/42 (38%), Positives = 26/42 (61%), Gaps = 3/42 (7%)

Query: 148 RLHFEALMNIPVLVLDVNDDFSEEVTKQEDLMREVNTFVKNL 189
           + +F+ L  +P+L LDVN+DF +   K E L+ +V  F+  L
Sbjct: 222 KTNFDYLQEVPILTLDVNEDFKD---KYESLVEKVKEFLSTL 260


>gi|92859641 thymidine kinase 2, mitochondrial [Homo sapiens]
          Length = 307

 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 34/111 (30%), Positives = 54/111 (48%), Gaps = 20/111 (18%)

Query: 41  LSIEGNIAVGKSTFVKLLTKTYPEWHVATEPVATWQNIQAAGTQKACTAQSLGNLLDMMY 100
           + +EGNIA GK+T ++  +    +  V TEPV+ W+N++              N L +MY
Sbjct: 95  ICVEGNIASGKTTCLEFFSNA-TDVEVLTEPVSKWRNVRGH------------NPLGLMY 141

Query: 101 REPARWSYTFQTFSFLSRLKVQLEPFPEKLLQARKPVQIFERSVYSDRLHF 151
            + +RW  T QT+  L+ L     P           V++ ERS++S R  F
Sbjct: 142 HDASRWGLTLQTYVQLTMLDRHTRP-------QVSSVRLMERSIHSARYIF 185


>gi|4758768 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10,
           42kDa precursor [Homo sapiens]
          Length = 355

 Score = 35.8 bits (81), Expect = 0.023
 Identities = 39/141 (27%), Positives = 61/141 (43%), Gaps = 18/141 (12%)

Query: 39  RRLSIEGNIAVGKSTFVKLLT-----KTYPEWHVATEPVATWQNIQAAGTQKACTAQSLG 93
           R ++++GNI  GK    K +      K +PE  +      T       G  K       G
Sbjct: 58  RVITVDGNICTGKGKLAKEIAEKLGFKHFPEAGIHYPDSTT-------GDGKPLATDYNG 110

Query: 94  NL-LDMMYREPARW---SYTFQTFSFLSRLKVQLEPFPEKLLQARKPVQIFERSVYSDRL 149
           N  L+  Y +P      SY  Q++ + SRL +Q     E LL   + V + ERS++SD +
Sbjct: 111 NCSLEKFYDDPRSNDGNSYRLQSWLYSSRL-LQYSDALEHLLTTGQGV-VLERSIFSDFV 168

Query: 150 HFEALMNIPVLVLDVNDDFSE 170
             EA+ N   +     D ++E
Sbjct: 169 FLEAMYNQGFIRKQCVDHYNE 189


>gi|11342678 amyloid beta (A4) precursor protein-binding, family A,
           member 3 [Homo sapiens]
          Length = 575

 Score = 32.3 bits (72), Expect = 0.25
 Identities = 14/52 (26%), Positives = 28/52 (53%)

Query: 25  GVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTKTYPEWHVATEPVATWQ 76
           G++   G+  G     ++ +  +A   +  ++LLT+ Y E H+ T P AT++
Sbjct: 513 GIAERGGIRVGHRIIEINGQSVVATPHARIIELLTEAYGEVHIKTMPAATYR 564


>gi|4557537 developmentally regulated GTP binding protein 2 [Homo
          sapiens]
          Length = 364

 Score = 27.7 bits (60), Expect = 6.1
 Identities = 13/28 (46%), Positives = 19/28 (67%)

Query: 37 GPRRLSIEGNIAVGKSTFVKLLTKTYPE 64
          G  R+++ G  +VGKSTF+ L+T T  E
Sbjct: 61 GDARVALIGFPSVGKSTFLSLMTSTASE 88


>gi|122056683 FRAS1 related extracellular matrix 1 [Homo sapiens]
          Length = 2179

 Score = 27.7 bits (60), Expect = 6.1
 Identities = 14/38 (36%), Positives = 18/38 (47%), Gaps = 5/38 (13%)

Query: 69   TEPVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARW 106
            TE   TW         +AC  Q LGNL+ +  R+  RW
Sbjct: 2069 TEQKGTWN-----AAAQACREQYLGNLVTVFSRQHMRW 2101


>gi|239754042 PREDICTED: similar to hCG1646049 [Homo sapiens]
          Length = 346

 Score = 27.3 bits (59), Expect = 8.0
 Identities = 14/40 (35%), Positives = 21/40 (52%)

Query: 10  RLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAV 49
           +L  PF  +A+S      + R L A RG R L   G++A+
Sbjct: 284 KLSPPFPCLAQSASRAAGARRALSASRGRRGLLGSGSLAL 323


>gi|239748572 PREDICTED: similar to hCG1646049 [Homo sapiens]
          Length = 346

 Score = 27.3 bits (59), Expect = 8.0
 Identities = 14/40 (35%), Positives = 21/40 (52%)

Query: 10  RLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAV 49
           +L  PF  +A+S      + R L A RG R L   G++A+
Sbjct: 284 KLSPPFPCLAQSASRAAGARRALSASRGRRGLLGSGSLAL 323


>gi|169167670 PREDICTED: similar to hCG1646049 [Homo sapiens]
          Length = 346

 Score = 27.3 bits (59), Expect = 8.0
 Identities = 14/40 (35%), Positives = 21/40 (52%)

Query: 10  RLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAV 49
           +L  PF  +A+S      + R L A RG R L   G++A+
Sbjct: 284 KLSPPFPCLAQSASRAAGARRALSASRGRRGLLGSGSLAL 323


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.133    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,550,058
Number of Sequences: 37866
Number of extensions: 265737
Number of successful extensions: 705
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 690
Number of HSP's gapped (non-prelim): 13
length of query: 189
length of database: 18,247,518
effective HSP length: 96
effective length of query: 93
effective length of database: 14,612,382
effective search space: 1358951526
effective search space used: 1358951526
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.