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Search of human proteins with 110611923
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110611923 killer cell immunoglobulin-like receptor, two
domains, long cytoplasmic tail, 1 [Homo sapiens]
(348 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110611923 killer cell immunoglobulin-like receptor, two domai... 720 0.0
gi|134304833 killer cell immunoglobulin-like receptor, two domai... 684 0.0
gi|71143139 killer cell immunoglobulin-like receptor, two domain... 646 0.0
gi|7657277 killer cell immunoglobulin-like receptor, two domains... 587 e-168
gi|6912472 killer cell immunoglobulin-like receptor, two domains... 570 e-163
gi|134268644 killer cell immunoglobulin-like receptor, three dom... 567 e-162
gi|6912474 killer cell immunoglobulin-like receptor, two domains... 556 e-158
gi|134304835 killer cell immunoglobulin-like receptor, two domai... 556 e-158
gi|116517309 killer cell immunoglobulin-like receptor, two domai... 547 e-156
gi|134268642 killer cell immunoglobulin-like receptor, three dom... 544 e-155
gi|46488946 killer cell immunoglobulin-like receptor, three doma... 454 e-128
gi|11968154 killer cell immunoglobulin-like receptor, two domain... 447 e-126
gi|66267727 killer cell immunoglobulin-like receptor, two domain... 436 e-122
gi|134133244 killer cell immunoglobulin-like receptor, three dom... 422 e-118
gi|124107606 killer cell immunoglobulin-like receptor, two domai... 420 e-118
gi|124107610 killer cell immunoglobulin-like receptor, two domai... 357 7e-99
gi|62632748 killer-cell Ig-like receptor [Homo sapiens] 357 9e-99
gi|124107604 killer cell immunoglobulin-like receptor, two domai... 317 8e-87
gi|71143143 killer cell immunoglobulin-like receptor, two domain... 302 3e-82
gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B... 189 3e-48
gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B... 186 2e-47
gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B... 184 1e-46
gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B... 184 1e-46
gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B... 183 2e-46
gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B... 182 3e-46
gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B... 180 2e-45
gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B... 179 3e-45
gi|125987593 leukocyte immunoglobulin-like receptor, subfamily B... 173 2e-43
gi|125987591 leukocyte immunoglobulin-like receptor, subfamily B... 173 2e-43
gi|5803070 leukocyte immunoglobulin-like receptor, subfamily B, ... 172 5e-43
>gi|110611923 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 1 [Homo sapiens]
Length = 348
Score = 720 bits (1859), Expect = 0.0
Identities = 348/348 (100%), Positives = 348/348 (100%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL
Sbjct: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120
HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI
Sbjct: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120
Query: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGT 180
VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGT
Sbjct: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGT 180
Query: 181 FQADFPLGPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
FQADFPLGPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGN
Sbjct: 181 FQADFPLGPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
Query: 241 PRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEV 300
PRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEV
Sbjct: 241 PRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEV 300
Query: 301 TYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP 348
TYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP
Sbjct: 301 TYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP 348
>gi|134304833 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 2 precursor [Homo sapiens]
Length = 348
Score = 684 bits (1764), Expect = 0.0
Identities = 331/348 (95%), Positives = 334/348 (95%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
MSL+VVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDV FEHFLL
Sbjct: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120
HREG F DTL LIGEHHDGVSKANFSI M QDLAGTYRCYGSVTHSPYQ+SAPSDPLDI
Sbjct: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
Query: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGT 180
VI GLYEKPSLSAQ GPTVLAGE+VTLSCSSRSSYDMYHLSREGEAHE R AGPKVNGT
Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT 180
Query: 181 FQADFPLGPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
FQADFPLGPATHGGTYRCFGSF DSPYEWS SSDPLLVSVTGNPSNSWPSPTEPSSKTGN
Sbjct: 181 FQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
Query: 241 PRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEV 300
PRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEV
Sbjct: 241 PRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEV 300
Query: 301 TYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP 348
TYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP
Sbjct: 301 TYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP 348
>gi|71143139 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 3 isoform 2 [Homo sapiens]
Length = 341
Score = 646 bits (1667), Expect = 0.0
Identities = 312/340 (91%), Positives = 318/340 (93%), Gaps = 1/340 (0%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
MSL+VVSM CVGFFLLQGAWPHEGVHRKPSLLAHPG LVKSEETVILQCWSDV F+HFLL
Sbjct: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120
HREG F DTL LIGEHHDGVSKANFSI M QDLAGTYRCYGSVTHSPYQ+SAPSDPLDI
Sbjct: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
Query: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGT 180
VI GLYEKPSLSAQ GPTVLAGE+VTLSCSSRSSYDMYHLSREGEAHERR AGPKVNGT
Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGT 180
Query: 181 FQADFPLGPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
FQADFPLGPATHGGTYRCFGSF DSPYEWS SSDPLLVSVTGNPSNSWPSPTEPSS+TGN
Sbjct: 181 FQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSETGN 240
Query: 241 PRHLHILIGTSVVIILFI-LLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQE 299
PRHLH+LIGTSVVIILFI LLFFLLHRWC NKKNA VMDQE AGNRT N EDSDEQDPQE
Sbjct: 241 PRHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQE 300
Query: 300 VTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAE 339
VTY QLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAE
Sbjct: 301 VTYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAE 340
>gi|7657277 killer cell immunoglobulin-like receptor, two domains,
short cytoplasmic tail, 1 precursor [Homo sapiens]
Length = 304
Score = 587 bits (1514), Expect = e-168
Identities = 286/303 (94%), Positives = 292/303 (96%), Gaps = 1/303 (0%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
MSL VVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL
Sbjct: 1 MSLTVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120
HREGMFNDTLRLIGEHHDGVSKANFSISRM QDLAGTYRCYGSVTHSPYQ+SAPSDPLDI
Sbjct: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMKQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
Query: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGT 180
VIIGLYEKPSLSAQ GPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAG KVNGT
Sbjct: 121 VIIGLYEKPSLSAQPGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGTKVNGT 180
Query: 181 FQADFPLGPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
FQA+FPLGPATHGGTYRCFGSF DSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSS+TGN
Sbjct: 181 FQANFPLGPATHGGTYRCFGSFRDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSETGN 240
Query: 241 PRHLHILIGTSVVIILF-ILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQE 299
PRHLH+LIGTSVV I F ILLFFLLHRWCS+KKNAAVMDQE AGNRT NSEDSDEQD QE
Sbjct: 241 PRHLHVLIGTSVVKIPFTILLFFLLHRWCSDKKNAAVMDQEPAGNRTVNSEDSDEQDHQE 300
Query: 300 VTY 302
V+Y
Sbjct: 301 VSY 303
>gi|6912472 killer cell immunoglobulin-like receptor, two domains,
short cytoplasmic tail, 2 precursor [Homo sapiens]
Length = 304
Score = 570 bits (1468), Expect = e-163
Identities = 277/303 (91%), Positives = 283/303 (93%), Gaps = 1/303 (0%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
MSL+VVSMACVGFFLLQGAWPHEGVHRKPSLLAHPG LVKSEETVILQCWSDV FEHFLL
Sbjct: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFEHFLL 60
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120
HREG + DTL LIGEHHDGVSKANFSI M QDLAGTYRCYGSVTHSPYQ+SAPSDPLDI
Sbjct: 61 HREGKYKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
Query: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGT 180
VI GLYEKPSLSAQ GPTVLAGE+VTLSCSSRSSYDMYHLSREGEAHERR AGPKVNGT
Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGT 180
Query: 181 FQADFPLGPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
FQADFPLGPATHGGTYRCFGSF DSPYEWS SSDPLLVSVTGNPSNSWPSPTEPSSKTGN
Sbjct: 181 FQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
Query: 241 PRHLHILIGTSVVIILF-ILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQE 299
PRHLH+LIGTSVV I F ILLFFLLHRWCSNKKNAAVMDQE AGNRT NSEDSDEQD QE
Sbjct: 241 PRHLHVLIGTSVVKIPFTILLFFLLHRWCSNKKNAAVMDQEPAGNRTVNSEDSDEQDHQE 300
Query: 300 VTY 302
V+Y
Sbjct: 301 VSY 303
>gi|134268644 killer cell immunoglobulin-like receptor, three
domains, long cytoplasmic tail, 1 precursor [Homo
sapiens]
Length = 444
Score = 567 bits (1462), Expect = e-162
Identities = 283/360 (78%), Positives = 302/360 (83%), Gaps = 17/360 (4%)
Query: 6 VSMACVGFFLLQGAWPHE----------------GVHRKPSLLAHPGRLVKSEETVILQC 49
V+ A G + +G+ PH G HRKPSLLAHPG LVKS E VILQC
Sbjct: 85 VTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGERVILQC 144
Query: 50 WSDVMFEHFLLHREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPY 109
WSD+MFEHF LH+EG+ D RL+G+ HDGVSKANFSI M LAGTYRCYGSVTH+PY
Sbjct: 145 WSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYGSVTHTPY 204
Query: 110 QVSAPSDPLDIVIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHER 169
Q+SAPSDPLDIV+ G YEKPSLSAQ GP V AGE+VTLSCSSRSSYDMYHLSREG AHER
Sbjct: 205 QLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHER 264
Query: 170 RLPAGPKVNGTFQADFPLGPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWP 229
RLPA KVN TFQADFPLGPATHGGTYRCFGSF SPYEWS SDPLLVSVTGNPS+SWP
Sbjct: 265 RLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSWP 324
Query: 230 SPTEPSSKTGNPRHLHILIGTSVVIILFI-LLFFLLHRWCSNKKNAAVMDQESAGNRTAN 288
SPTEPSSK+GNPRHLHILIGTSVVIILFI LLFFLLH WCSNKKNAAVMDQE AGNRTAN
Sbjct: 325 SPTEPSSKSGNPRHLHILIGTSVVIILFILLLFFLLHLWCSNKKNAAVMDQEPAGNRTAN 384
Query: 289 SEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP 348
SEDSDEQDP+EVTY QL+HCVFTQRKITRPSQRPKTPPTD I+YTELPNA+ RSKVVSCP
Sbjct: 385 SEDSDEQDPEEVTYAQLDHCVFTQRKITRPSQRPKTPPTDTILYTELPNAKPRSKVVSCP 444
Score = 153 bits (386), Expect = 3e-37
Identities = 92/224 (41%), Positives = 127/224 (56%), Gaps = 7/224 (3%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
MSL+VVSMACVG FL+Q A PH G KP L A P +V V L+C F +F+L
Sbjct: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120
++E + I H + + +F++S +T AG Y C GS HSP SAPS+P+ I
Sbjct: 61 YKEDRIH-----IPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVI 115
Query: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGT 180
++ G + KPSL A GP V +GE V L C S ++ + L +EG + + G +G
Sbjct: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGV 175
Query: 181 FQADFPLGP--ATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTG 222
+A+F +GP GTYRC+GS +PY+ S SDPL + VTG
Sbjct: 176 SKANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTG 219
>gi|6912474 killer cell immunoglobulin-like receptor, two domains,
short cytoplasmic tail, 3 [Homo sapiens]
Length = 304
Score = 556 bits (1432), Expect = e-158
Identities = 271/303 (89%), Positives = 279/303 (92%), Gaps = 1/303 (0%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
MSL+V+SMACVGFF LQGAWPHEG RKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL
Sbjct: 1 MSLMVISMACVGFFWLQGAWPHEGFRRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120
HREG FNDTLRLIGEH DGVSKANFSI RM QDLAGTYRCYGSV HSPYQ SAPSDPLDI
Sbjct: 61 HREGTFNDTLRLIGEHIDGVSKANFSIGRMRQDLAGTYRCYGSVPHSPYQFSAPSDPLDI 120
Query: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGT 180
VI GLYEKPSLSAQ GPTVLAGE+VTLSCSS SSYDMYHLS EGEAHERR AGPKVNGT
Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSWSSYDMYHLSTEGEAHERRFSAGPKVNGT 180
Query: 181 FQADFPLGPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
FQADFPLGPAT GGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGN
Sbjct: 181 FQADFPLGPATQGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
Query: 241 PRHLHILIGTSVVIILF-ILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQE 299
PRHLH+LIGTSVV + F ILLFFLLHRWCS+KKNA+VMDQ AGNRT N EDSDEQD QE
Sbjct: 241 PRHLHVLIGTSVVKLPFTILLFFLLHRWCSDKKNASVMDQGPAGNRTVNREDSDEQDHQE 300
Query: 300 VTY 302
V+Y
Sbjct: 301 VSY 303
>gi|134304835 killer cell immunoglobulin-like receptor, two domains,
short cytoplasmic tail, 5 [Homo sapiens]
Length = 304
Score = 556 bits (1432), Expect = e-158
Identities = 271/303 (89%), Positives = 280/303 (92%), Gaps = 1/303 (0%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
MSL+V+SMACV FFLLQGAWPHEG RKPSLLAHPG LVKSEETVILQCWSDVMFEHFLL
Sbjct: 1 MSLMVISMACVAFFLLQGAWPHEGFRRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLL 60
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120
HREG FN TLRLIGEH DGVSK NFSI RMTQDLAGTYRCYGSVTHSPYQ+SAPSDPLDI
Sbjct: 61 HREGTFNHTLRLIGEHIDGVSKGNFSIGRMTQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
Query: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGT 180
VI GLYEKPSLSAQ GPTVLAGE+VTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVN T
Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNRT 180
Query: 181 FQADFPLGPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
FQADFPL PATHGGTYRCFGSF DSPYEWSKSSDPLLVSVTGN SNSWPSPTEPSS+TGN
Sbjct: 181 FQADFPLDPATHGGTYRCFGSFRDSPYEWSKSSDPLLVSVTGNSSNSWPSPTEPSSETGN 240
Query: 241 PRHLHILIGTSVVIILF-ILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQE 299
PRHLH+LIGTSVV + F ILLFFLLHRWCSNKKNA+VMDQ AGNRT N EDSDEQD QE
Sbjct: 241 PRHLHVLIGTSVVKLPFTILLFFLLHRWCSNKKNASVMDQGPAGNRTVNREDSDEQDHQE 300
Query: 300 VTY 302
V+Y
Sbjct: 301 VSY 303
>gi|116517309 killer cell immunoglobulin-like receptor, two domains,
short cytoplasmic tail, 4 [Homo sapiens]
Length = 304
Score = 547 bits (1410), Expect = e-156
Identities = 267/303 (88%), Positives = 277/303 (91%), Gaps = 1/303 (0%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
MSL+V+ MACVGFFLLQGAWP EGVHRKPS LA PG LVKSEETVILQCWSDVMFEHFLL
Sbjct: 1 MSLMVIIMACVGFFLLQGAWPQEGVHRKPSFLALPGHLVKSEETVILQCWSDVMFEHFLL 60
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120
HREG FN+TL LIGEHHDGVSKANFSI M LAGTYRCYGSV HSPYQ+SAPSDPLD+
Sbjct: 61 HREGKFNNTLHLIGEHHDGVSKANFSIGPMMPVLAGTYRCYGSVPHSPYQLSAPSDPLDM 120
Query: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGT 180
VIIGLYEKPSLSAQ GPTV AGENVTLSCSSRSSYDMYHLSREGEAHERRLPA +NGT
Sbjct: 121 VIIGLYEKPSLSAQPGPTVQAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAVRSINGT 180
Query: 181 FQADFPLGPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
FQADFPLGPATHGGTYRCFGSF D+PYEWS SSDPLLVSVTGNPSNSWPSPTEPSSKTGN
Sbjct: 181 FQADFPLGPATHGGTYRCFGSFRDAPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
Query: 241 PRHLHILIGTSVVIILF-ILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQE 299
PRHLH+LIGTSVV I F ILLFFLLHRWCS+KKNAAVMDQE AGNRT NSEDSDEQD QE
Sbjct: 241 PRHLHVLIGTSVVKIPFTILLFFLLHRWCSDKKNAAVMDQEPAGNRTVNSEDSDEQDHQE 300
Query: 300 VTY 302
V+Y
Sbjct: 301 VSY 303
>gi|134268642 killer cell immunoglobulin-like receptor, three
domains, long cytoplasmic tail, 2 precursor [Homo
sapiens]
Length = 455
Score = 544 bits (1402), Expect = e-155
Identities = 276/360 (76%), Positives = 295/360 (81%), Gaps = 17/360 (4%)
Query: 6 VSMACVGFFLLQGAWPHE----------------GVHRKPSLLAHPGRLVKSEETVILQC 49
V+ A G + +G+ PH G HRKPSLLAHPG L+KS ETVILQC
Sbjct: 85 VTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGNHRKPSLLAHPGPLLKSGETVILQC 144
Query: 50 WSDVMFEHFLLHREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPY 109
WSDVMFEHF LHREG+ D RL+G+ HDGVSKANFSI + LAGTYRCYGSV HSPY
Sbjct: 145 WSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANFSIGPLMPVLAGTYRCYGSVPHSPY 204
Query: 110 QVSAPSDPLDIVIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHER 169
Q+SAPSDPLDIVI GLYEKPSLSAQ GPTV AGENVTLSCSS SSYD+YHLSREGEAHER
Sbjct: 205 QLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGENVTLSCSSWSSYDIYHLSREGEAHER 264
Query: 170 RLPAGPKVNGTFQADFPLGPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWP 229
RL A PKVN TFQADFPLGPATHGGTYRCFGSF P WS SSDPLLVSVTGNPS+SWP
Sbjct: 265 RLRAVPKVNRTFQADFPLGPATHGGTYRCFGSFRALPCVWSNSSDPLLVSVTGNPSSSWP 324
Query: 230 SPTEPSSKTGNPRHLHILIGTSVVIILFI-LLFFLLHRWCSNKKNAAVMDQESAGNRTAN 288
SPTEPSSK+G RHLH+LIGTSVVI LFI LLFFLL+RWCSNKKNAAVMDQE AG+RT N
Sbjct: 325 SPTEPSSKSGICRHLHVLIGTSVVIFLFILLLFFLLYRWCSNKKNAAVMDQEPAGDRTVN 384
Query: 289 SEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP 348
+DSDEQDPQEVTY QL+HCVF QRKI+RPSQRPKTP TD VYTELPNAE RSKVVSCP
Sbjct: 385 RQDSDEQDPQEVTYAQLDHCVFIQRKISRPSQRPKTPLTDTSVYTELPNAEPRSKVVSCP 444
Score = 161 bits (407), Expect = 9e-40
Identities = 101/238 (42%), Positives = 134/238 (56%), Gaps = 11/238 (4%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
MSL VVSMACVGFFLLQGAWP G KP L A P +V V LQC F +F+L
Sbjct: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120
++E + + H + + +F + +T AGTYRC GS HS SAPS+PL I
Sbjct: 61 YKEDRSHVPI-----FHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVI 115
Query: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGT 180
++ G + KPSL A GP + +GE V L C S ++ + L REG + + G +G
Sbjct: 116 MVTGNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGV 175
Query: 181 FQADFPLGP--ATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTG---NPS-NSWPSPT 232
+A+F +GP GTYRC+GS SPY+ S SDPL + +TG PS ++ P PT
Sbjct: 176 SKANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPT 233
>gi|46488946 killer cell immunoglobulin-like receptor, three
domains, long cytoplasmic tail, 3 [Homo sapiens]
Length = 410
Score = 454 bits (1168), Expect = e-128
Identities = 229/309 (74%), Positives = 247/309 (79%), Gaps = 18/309 (5%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGMFNDTLRLIGEHHDGVSKA 83
GVHRKPSLLAHPG LVKS ETVILQCWSDV FE FLLHREG+ D LRL+G+ HD S+
Sbjct: 119 GVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQV 178
Query: 84 NFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDIVIIGLYEKPSLSAQLGPTVLAGE 143
N+S+ MT LAGTYRC+GSVTH PY++SAPSDPLDIV++GLY KPSLSAQ GPTV AGE
Sbjct: 179 NYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGE 238
Query: 144 NVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGTFQADFPLGPATHGGTYRCFGSFH 203
NVTLSCSSRS +D+YHLSRE EA E RL A +VNGTFQA+FPLGP THGG YRCFGSF
Sbjct: 239 NVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFR 298
Query: 204 DSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGNPRHLHILIGTSVVIILF-ILLFF 262
P+ WS SDPL VSV TGN RHLH+LIGTSVVII F ILLFF
Sbjct: 299 ALPHAWSDPSDPLPVSV-----------------TGNSRHLHVLIGTSVVIIPFAILLFF 341
Query: 263 LLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRP 322
LLHRWC+NKKNA VMDQE AGNRT N EDSDEQDPQEVTY QLNHCVFTQRKITRPSQRP
Sbjct: 342 LLHRWCANKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRP 401
Query: 323 KTPPTDIIV 331
KTPPTD V
Sbjct: 402 KTPPTDTSV 410
Score = 167 bits (424), Expect = 1e-41
Identities = 104/239 (43%), Positives = 137/239 (57%), Gaps = 13/239 (5%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
MSL+VVSMACVGFFLL+G WPH G KP L A PG +V + V LQC S + F F L
Sbjct: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60
Query: 61 HRE-GMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLD 119
+E GM + E ++ + + +F + +T AGTYRC S HSP SAPS+P+
Sbjct: 61 SKEDGM------PVPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVV 114
Query: 120 IVIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNG 179
I++ G++ KPSL A GP V +GE V L C S ++ + L REG + G +
Sbjct: 115 IMVTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDA 174
Query: 180 TFQADFPLGPATH--GGTYRCFGSFHDSPYEWSKSSDPL---LVSVTGNPS-NSWPSPT 232
Q ++ +GP T GTYRCFGS PYE S SDPL +V + G PS ++ P PT
Sbjct: 175 GSQVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPT 233
>gi|11968154 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 5A [Homo sapiens]
Length = 375
Score = 447 bits (1149), Expect = e-126
Identities = 235/343 (68%), Positives = 260/343 (75%), Gaps = 6/343 (1%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
MSL+V+SMACVGFFLLQGAW HEG KP L A P +V V L C S + F F L
Sbjct: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120
++E + E ++ + + + +T AGTYRC GS SP + SAPS+PL I
Sbjct: 61 YKEDGVP-----VPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVI 115
Query: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGT 180
V+ GL+ KPSLSAQ GPTV GENVTLSCSSRSS+DMYHLSREG AHE RLPA P VNGT
Sbjct: 116 VVTGLFGKPSLSAQPGPTVRTGENVTLSCSSRSSFDMYHLSREGRAHEPRLPAVPSVNGT 175
Query: 181 FQADFPLGPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
FQADFPLGPATHGGTY CFGS HDSPYEWS SDPLLVSVTGN S+S SPTEPSSKTG
Sbjct: 176 FQADFPLGPATHGGTYTCFGSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGI 235
Query: 241 PRHLHILIGTSVVIILFILL-FFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQE 299
RHLHILIGTSV IILFI+L FFLLH CSNKKNAAVMDQE AG+RT N EDSD+QDPQE
Sbjct: 236 RRHLHILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQEPAGDRTVNREDSDDQDPQE 295
Query: 300 VTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRS 342
VTY QL+HCVFTQ KIT PSQRPKTPPTD +Y ELPNA+ RS
Sbjct: 296 VTYAQLDHCVFTQTKITSPSQRPKTPPTDTTMYMELPNAKPRS 338
>gi|66267727 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 5B precursor [Homo sapiens]
Length = 375
Score = 436 bits (1121), Expect = e-122
Identities = 230/343 (67%), Positives = 256/343 (74%), Gaps = 6/343 (1%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
MSL+V+SMACVGFFLLQGAW HEG KP L A P +V V L C S + F F L
Sbjct: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120
++E + E ++ + + + +T AGTYRC GS SP + SAPS+PL I
Sbjct: 61 YKEDGVP-----VPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVI 115
Query: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGT 180
V+ GL+ KPSLSAQ GPTV GENV LSCSSRSS+DMYHLSREG AHE RLPA P V+GT
Sbjct: 116 VVTGLFGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGT 175
Query: 181 FQADFPLGPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
FQADFPLGPATHGGTY CF S HDSPYEWS SDPLLVSVTGN S+S SPTEPSSKTG
Sbjct: 176 FQADFPLGPATHGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGI 235
Query: 241 PRHLHILIGTSVVIILFILL-FFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQE 299
RHLHILIGTSV IILFI+L FFLLH CSNKKNAAVMDQ AG+RT N EDSD+QDPQE
Sbjct: 236 RRHLHILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQGPAGDRTVNREDSDDQDPQE 295
Query: 300 VTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRS 342
VTY QL+HCVFTQ KIT PSQRPK PPTD +Y ELPNA+ RS
Sbjct: 296 VTYAQLDHCVFTQTKITSPSQRPKAPPTDTTMYMELPNAKPRS 338
>gi|134133244 killer cell immunoglobulin-like receptor, three
domains, short cytoplasmic tail, 1 [Homo sapiens]
Length = 382
Score = 422 bits (1085), Expect = e-118
Identities = 213/284 (75%), Positives = 229/284 (80%), Gaps = 17/284 (5%)
Query: 6 VSMACVGFFLLQGAWPHE----------------GVHRKPSLLAHPGRLVKSEETVILQC 49
V+ A G + +G+ PH G HRKPSLLAHPG LVKS E VILQC
Sbjct: 85 VTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSGERVILQC 144
Query: 50 WSDVMFEHFLLHREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPY 109
WSD+MFEHF LH+E + D RL+G+ HDGVSKANFSI M + LAGTYRCYGSVTH+PY
Sbjct: 145 WSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYGSVTHTPY 204
Query: 110 QVSAPSDPLDIVIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHER 169
Q+SAPSDPLDIV+ GLYEKPSLSAQ GP V AGE+VTLSCSSRSSYDMYHLSREG AHER
Sbjct: 205 QLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHER 264
Query: 170 RLPAGPKVNGTFQADFPLGPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWP 229
RLPA KVN TFQADFPLGPATHGGTYRCFGSF SPYEWS SDPLLVSVTGNPS+SWP
Sbjct: 265 RLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSWP 324
Query: 230 SPTEPSSKTGNPRHLHILIGTSVVIILF-ILLFFLLHRWCSNKK 272
SPTEPSSK+GN RHLHILIGTSVV I F ILLFFLLHRWCSNKK
Sbjct: 325 SPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFFLLHRWCSNKK 368
Score = 145 bits (365), Expect = 7e-35
Identities = 88/224 (39%), Positives = 123/224 (54%), Gaps = 7/224 (3%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
M L+VVSMACVG FL+Q A PH G KP L A P +V V L+C F +F+L
Sbjct: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120
++E + + H + + F++S +T AG Y C GS HSP SAPS+P+ I
Sbjct: 61 YKEDRIHVPI-----FHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVI 115
Query: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGT 180
++ G + KPSL A GP V +GE V L C S ++ + L +E + + G +G
Sbjct: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGV 175
Query: 181 FQADFPLGPATH--GGTYRCFGSFHDSPYEWSKSSDPLLVSVTG 222
+A+F +G GTYRC+GS +PY+ S SDPL + VTG
Sbjct: 176 SKANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTG 219
>gi|124107606 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 4 isoform a [Homo sapiens]
Length = 377
Score = 420 bits (1080), Expect = e-118
Identities = 220/343 (64%), Positives = 251/343 (73%), Gaps = 6/343 (1%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
MS V+ +AC+GFFL Q W H G KP A P +V V L+C F F L
Sbjct: 3 MSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTL 62
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120
+++ + E ++ + +F IS +T AGTYRC G HSP + SAPS+PL I
Sbjct: 63 YKKDGVP-----VPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVI 117
Query: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGT 180
++ GLYEKPSL+A+ GPTV AGENVTLSCSS+SS+D+YHLSREGEAHE RLPA P +NGT
Sbjct: 118 MVTGLYEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGT 177
Query: 181 FQADFPLGPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
FQADFPLGPATHG TYRCFGSFH SPYEWS SDPL VSVTGNPS+SWPSPTEPS KTG
Sbjct: 178 FQADFPLGPATHGETYRCFGSFHGSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKTGI 237
Query: 241 PRHLHILIGTSVVIILF-ILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQE 299
RHLH +I SV IILF IL FFLLHRWCS KKNAAVM+QE AG+RT N EDSDEQDPQE
Sbjct: 238 ARHLHAVIRYSVAIILFTILPFFLLHRWCSKKKNAAVMNQEPAGHRTVNREDSDEQDPQE 297
Query: 300 VTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRS 342
VTY QL+HC+FTQRKIT PSQR K P TD V ELPNAE R+
Sbjct: 298 VTYAQLDHCIFTQRKITGPSQRSKRPSTDTSVCIELPNAEPRA 340
>gi|124107610 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 4 isoform c [Homo sapiens]
Length = 342
Score = 357 bits (917), Expect = 7e-99
Identities = 194/342 (56%), Positives = 225/342 (65%), Gaps = 39/342 (11%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
MS V+ +AC+GFFL Q W H G KP A P +V V L+C F F L
Sbjct: 3 MSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTL 62
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120
+++ + E ++ + +F IS +T AGTYRC G HSP + SAPS+PL I
Sbjct: 63 YKKDGVP-----VPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVI 117
Query: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGT 180
++ GLYEKPSL+A+ GPTV AGENVTLSCSS+SS+D+YHLSREGEAHE RLPA P +NGT
Sbjct: 118 MVTGLYEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGT 177
Query: 181 FQADFPLGPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
FQADFPLGPATHG TYRCFGSFH SPYEWS SDPL VSVTGNPS+SWPSPTEPS KT
Sbjct: 178 FQADFPLGPATHGETYRCFGSFHGSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKT-- 235
Query: 241 PRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEV 300
+AAVM+QE AG+RT N EDSDEQDPQEV
Sbjct: 236 --------------------------------DAAVMNQEPAGHRTVNREDSDEQDPQEV 263
Query: 301 TYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRS 342
TY QL+HC+FTQRKIT PSQR K P TD V ELPNAE R+
Sbjct: 264 TYAQLDHCIFTQRKITGPSQRSKRPSTDTSVCIELPNAEPRA 305
>gi|62632748 killer-cell Ig-like receptor [Homo sapiens]
Length = 328
Score = 357 bits (916), Expect = 9e-99
Identities = 181/232 (78%), Positives = 189/232 (81%), Gaps = 16/232 (6%)
Query: 6 VSMACVGFFLLQGAWPH----------------EGVHRKPSLLAHPGRLVKSEETVILQC 49
V+ A G + +G+ PH GVHRKPSLLAHPG LVKSEETVILQC
Sbjct: 85 VTPAHAGTYRCRGSHPHFLTGWSAPSNPLVIMVTGVHRKPSLLAHPGPLVKSEETVILQC 144
Query: 50 WSDVMFEHFLLHREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPY 109
WSDVMFEHFLLHREG FNDTLRL GE HDGVSKANFSI RMTQDLAGTYRCYGSV HSPY
Sbjct: 145 WSDVMFEHFLLHREGKFNDTLRLTGELHDGVSKANFSIGRMTQDLAGTYRCYGSVPHSPY 204
Query: 110 QVSAPSDPLDIVIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHER 169
Q+SAPSDPLDIVI GL KPSLSAQ P V AGE+VTLSCSSRSSYD+YHLSREGEAHE
Sbjct: 205 QLSAPSDPLDIVITGLCGKPSLSAQPRPMVKAGESVTLSCSSRSSYDIYHLSREGEAHEL 264
Query: 170 RLPAGPKVNGTFQADFPLGPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVT 221
R PA PKVNGTFQA+FPLGPATHGGTYRCFGSF DSPYEWS SDPLLVSVT
Sbjct: 265 RFPAVPKVNGTFQANFPLGPATHGGTYRCFGSFRDSPYEWSDLSDPLLVSVT 316
Score = 162 bits (411), Expect = 3e-40
Identities = 100/225 (44%), Positives = 130/225 (57%), Gaps = 9/225 (4%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
MSL+V+SMACVGFFLLQGAW HEG KP L A P +V E V LQC S + F F L
Sbjct: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPFLSAWPSPVVSEGEHVALQCRSRLGFNEFSL 60
Query: 61 HRE-GMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLD 119
+E GM + E ++ V + I +T AGTYRC GS H SAPS+PL
Sbjct: 61 SKEDGM------PVPELYNRVFRNTVFIGPVTPAHAGTYRCRGSHPHFLTGWSAPSNPLV 114
Query: 120 IVIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNG 179
I++ G++ KPSL A GP V + E V L C S ++ + L REG+ ++ G +G
Sbjct: 115 IMVTGVHRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLLHREGKFNDTLRLTGELHDG 174
Query: 180 TFQADFPLGPATH--GGTYRCFGSFHDSPYEWSKSSDPLLVSVTG 222
+A+F +G T GTYRC+GS SPY+ S SDPL + +TG
Sbjct: 175 VSKANFSIGRMTQDLAGTYRCYGSVPHSPYQLSAPSDPLDIVITG 219
>gi|124107604 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 4 isoform b [Homo sapiens]
Length = 273
Score = 317 bits (813), Expect = 8e-87
Identities = 168/273 (61%), Positives = 194/273 (71%), Gaps = 6/273 (2%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
MS V+ +AC+GFFL Q W H G KP A P +V V L+C F F L
Sbjct: 3 MSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTL 62
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120
+++ + E ++ + +F IS +T AGTYRC G HSP + SAPS+PL I
Sbjct: 63 YKKDGVP-----VPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVI 117
Query: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGT 180
++ GLYEKPSL+A+ GPTV AGENVTLSCSS+SS+D+YHLSREGEAHE RLPA P +NGT
Sbjct: 118 MVTGLYEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGT 177
Query: 181 FQADFPLGPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
FQADFPLGPATHG TYRCFGSFH SPYEWS SDPL VSVTGNPS+SWPSPTEPS KTG
Sbjct: 178 FQADFPLGPATHGETYRCFGSFHGSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKTGI 237
Query: 241 PRHLHILIGTSVVIILF-ILLFFLLHRWCSNKK 272
RHLH +I SV IILF IL FFLLHRWCS KK
Sbjct: 238 ARHLHAVIRYSVAIILFTILPFFLLHRWCSKKK 270
>gi|71143143 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 3 isoform 1 [Homo sapiens]
Length = 243
Score = 302 bits (774), Expect = 3e-82
Identities = 154/219 (70%), Positives = 169/219 (77%), Gaps = 3/219 (1%)
Query: 124 GLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGTFQA 183
G++ KPSL A GP V + E V L C S + + L REG+ + G +G +A
Sbjct: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83
Query: 184 DFPLGPATH--GGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGNP 241
+F +GP GTYRC+GS SPY+ S SDPLLVSVTGNPSNSWPSPTEPSS+TGNP
Sbjct: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNP 143
Query: 242 RHLHILIGTSVVIILFILL-FFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEV 300
RHLH+LIGTSVVIILFILL FFLLHRWC NKKNA VMDQE AGNRT N EDSDEQDPQEV
Sbjct: 144 RHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEV 203
Query: 301 TYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAE 339
TY QLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAE
Sbjct: 204 TYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAE 242
Score = 227 bits (579), Expect = 1e-59
Identities = 107/124 (86%), Positives = 112/124 (90%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
MSL+VVSM CVGFFLLQGAWPHEGVHRKPSLLAHPG LVKSEETVILQCWSDV F+HFLL
Sbjct: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120
HREG F DTL LIGEHHDGVSKANFSI M QDLAGTYRCYGSVTHSPYQ+SAPSDPL +
Sbjct: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120
Query: 121 VIIG 124
+ G
Sbjct: 121 SVTG 124
>gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B,
member 3 isoform 2 [Homo sapiens]
Length = 631
Score = 189 bits (480), Expect = 3e-48
Identities = 126/352 (35%), Positives = 183/352 (51%), Gaps = 55/352 (15%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGMFNDTLRLIGEHHDGVSKA 83
GV RKPSLL G ++ +++ LQC SDV + F+L++EG + R + G+S+A
Sbjct: 220 GVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQA 279
Query: 84 NFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDIVIIG-LYEKPSLSAQLGPTVLAG 142
NF++ ++ G YRCYG+ S + SAPSDPL+I++ G +Y+ SLSAQ GPTV +G
Sbjct: 280 NFTLGPVSPSNGGQYRCYGAHNLSS-EWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASG 338
Query: 143 ENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGTFQADFPLGPAT--HGGTYRCFG 200
ENVTL C S +D + L++EG AH +QA+FP+ P T H GTYRC+G
Sbjct: 339 ENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYG 398
Query: 201 SFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGNPRHLHILIGTSV--VIILFI 258
S+ +P+ S S+PL + V+G+ S PT P S G R+L +LIG SV V++LF+
Sbjct: 399 SYSSNPHLLSHPSEPLELVVSGHSGGSSLPPTGPPSTPGLGRYLEVLIGVSVAFVLLLFL 458
Query: 259 LLFFLL-------HRWCSNKKN----------------------------------AAVM 277
LLF LL HR +K AAV
Sbjct: 459 LLFLLLRRQRHSKHRTSDQRKTDFQRPAGAAETEPKDRGLLRRSSPAADVQEENLYAAVK 518
Query: 278 DQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDI 329
D +S +S+ ++DPQ VTY + H + P + +PP+ +
Sbjct: 519 DTQSEDRVELDSQSPHDEDPQAVTYAPVKH--------SSPRREMASPPSSL 562
Score = 120 bits (300), Expect = 2e-27
Identities = 78/225 (34%), Positives = 115/225 (51%), Gaps = 8/225 (3%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
M+ + ++ C+G L G KP+L A PG ++ V + C + + L
Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRL 60
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120
H+EG R + +KA FSI MT+ AG YRC+ +S S PSDPL++
Sbjct: 61 HKEGSPEPLDR--NNPLEPKNKARFSIPSMTEHHAGRYRCH---YYSSAGWSEPSDPLEM 115
Query: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAH-ERRLPAGPKVNG 179
V+ G Y KP+LSA P V +G N+TL C S+ Y + L +EGE R L + +
Sbjct: 116 VMTGAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSR 175
Query: 180 TFQADFPLGPAT--HGGTYRCFGSFHDSPYEWSKSSDPLLVSVTG 222
FQA FP+GP T H + C+ + ++P+ WS SDPL + +G
Sbjct: 176 GFQALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSG 220
Score = 119 bits (299), Expect = 3e-27
Identities = 76/222 (34%), Positives = 114/222 (51%), Gaps = 9/222 (4%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGMFNDTLRLIGEH-HDGVSK 82
G + KP+L A P +V S + L+C S + HF+L +EG L + H +
Sbjct: 119 GAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQ 178
Query: 83 ANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDIVIIGLYEKPSLSAQLGPTVLAG 142
A F + +T + CY T++P+ S PSDPL+I+ G+ KPSL GP + G
Sbjct: 179 ALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPG 238
Query: 143 ENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGTFQADFPLGPA--THGGTYRCFG 200
+++TL C S Y+ + L +EGE + P G QA+F LGP ++GG YRC+G
Sbjct: 239 QSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYG 298
Query: 201 SFHDSPYEWSKSSDPLLVSVTGN-----PSNSWPSPTEPSSK 237
+ H+ EWS SDPL + + G ++ P PT S +
Sbjct: 299 A-HNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGE 339
Score = 77.0 bits (188), Expect = 2e-14
Identities = 88/341 (25%), Positives = 129/341 (37%), Gaps = 73/341 (21%)
Query: 30 SLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGMFNDTLRLIGEHHDGVSKANFSISR 89
SL A PG V S E V L C S F+ FLL +EG + LRL + +A F +S
Sbjct: 326 SLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSP 385
Query: 90 MTQDLAGTYRCYGSVTHSPYQVSAPSDPLDIVIIGLYEKPSLSAQLGPT---------VL 140
+T AGTYRCYGS + +P+ +S PS+PL++V+ G SL P+ VL
Sbjct: 386 VTSAHAGTYRCYGSYSSNPHLLSHPSEPLELVVSGHSGGSSLPPTGPPSTPGLGRYLEVL 445
Query: 141 AGENVT--------LSCSSRSSYDMYHLSREGEAHERRLPAG-----PKVNGTFQADFPL 187
G +V L R H + + + + PAG PK G + P
Sbjct: 446 IGVSVAFVLLLFLLLFLLLRRQRHSKHRTSDQRKTDFQRPAGAAETEPKDRGLLRRSSPA 505
Query: 188 GPATHGGTYRCFGSFHD---------SPYEWSKSSDPLLVSVT----GNPSNSWPSPTEP 234
Y SP++ DP V+ +P SP P
Sbjct: 506 ADVQEENLYAAVKDTQSEDRVELDSQSPHD----EDPQAVTYAPVKHSSPRREMASP--P 559
Query: 235 SSKTGNPRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDE 294
SS +G FL D++ +R ++E +
Sbjct: 560 SSLSGE---------------------FL-----------DTKDRQVEEDRQMDTEAAAS 587
Query: 295 QDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTEL 335
+ Q+VTY QL+ ++ P + PP + +Y L
Sbjct: 588 EASQDVTYAQLHSLTLRRKATEPPPSQEGEPPAEPSIYATL 628
>gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B,
member 3 isoform 1 [Homo sapiens]
Length = 632
Score = 186 bits (473), Expect = 2e-47
Identities = 127/353 (35%), Positives = 184/353 (52%), Gaps = 56/353 (15%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGMFNDTLRLIGEHHDGVSKA 83
GV RKPSLL G ++ +++ LQC SDV + F+L++EG + R + G+S+A
Sbjct: 220 GVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQA 279
Query: 84 NFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDIVIIG-LYEKPSLSAQLGPTVLAG 142
NF++ ++ G YRCYG+ S + SAPSDPL+I++ G +Y+ SLSAQ GPTV +G
Sbjct: 280 NFTLGPVSPSNGGQYRCYGAHNLSS-EWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASG 338
Query: 143 ENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGTFQADFPLGPAT--HGGTYRCFG 200
ENVTL C S +D + L++EG AH +QA+FP+ P T H GTYRC+G
Sbjct: 339 ENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYG 398
Query: 201 SFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGNPRHLHILIGTSV--VIILFI 258
S+ +P+ S S+PL + V+G+ S PT P S G R+L +LIG SV V++LF+
Sbjct: 399 SYSSNPHLLSHPSEPLELVVSGHSGGSSLPPTGPPSTPGLGRYLEVLIGVSVAFVLLLFL 458
Query: 259 LLFFLL-------HRWCSNKKN----------------------------------AAVM 277
LLF LL HR +K AAV
Sbjct: 459 LLFLLLRRQRHSKHRTSDQRKTDFQRPAGAAETEPKDRGLLRRSSPAADVQEENLYAAVK 518
Query: 278 DQESAGNRTANSEDS-DEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDI 329
D +S +S+ S ++DPQ VTY + H + P + +PP+ +
Sbjct: 519 DTQSEDRVELDSQQSPHDEDPQAVTYAPVKH--------SSPRREMASPPSSL 563
Score = 120 bits (300), Expect = 2e-27
Identities = 78/225 (34%), Positives = 115/225 (51%), Gaps = 8/225 (3%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
M+ + ++ C+G L G KP+L A PG ++ V + C + + L
Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRL 60
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120
H+EG R + +KA FSI MT+ AG YRC+ +S S PSDPL++
Sbjct: 61 HKEGSPEPLDR--NNPLEPKNKARFSIPSMTEHHAGRYRCH---YYSSAGWSEPSDPLEM 115
Query: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAH-ERRLPAGPKVNG 179
V+ G Y KP+LSA P V +G N+TL C S+ Y + L +EGE R L + +
Sbjct: 116 VMTGAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSR 175
Query: 180 TFQADFPLGPAT--HGGTYRCFGSFHDSPYEWSKSSDPLLVSVTG 222
FQA FP+GP T H + C+ + ++P+ WS SDPL + +G
Sbjct: 176 GFQALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSG 220
Score = 119 bits (299), Expect = 3e-27
Identities = 76/222 (34%), Positives = 114/222 (51%), Gaps = 9/222 (4%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGMFNDTLRLIGEH-HDGVSK 82
G + KP+L A P +V S + L+C S + HF+L +EG L + H +
Sbjct: 119 GAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQ 178
Query: 83 ANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDIVIIGLYEKPSLSAQLGPTVLAG 142
A F + +T + CY T++P+ S PSDPL+I+ G+ KPSL GP + G
Sbjct: 179 ALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPG 238
Query: 143 ENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGTFQADFPLGPA--THGGTYRCFG 200
+++TL C S Y+ + L +EGE + P G QA+F LGP ++GG YRC+G
Sbjct: 239 QSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYG 298
Query: 201 SFHDSPYEWSKSSDPLLVSVTGN-----PSNSWPSPTEPSSK 237
+ H+ EWS SDPL + + G ++ P PT S +
Sbjct: 299 A-HNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGE 339
Score = 78.2 bits (191), Expect = 1e-14
Identities = 83/329 (25%), Positives = 130/329 (39%), Gaps = 48/329 (14%)
Query: 30 SLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGMFNDTLRLIGEHHDGVSKANFSISR 89
SL A PG V S E V L C S F+ FLL +EG + LRL + +A F +S
Sbjct: 326 SLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSP 385
Query: 90 MTQDLAGTYRCYGSVTHSPYQVSAPSDPLDIVIIGLYEKPSLSAQLGPT---------VL 140
+T AGTYRCYGS + +P+ +S PS+PL++V+ G SL P+ VL
Sbjct: 386 VTSAHAGTYRCYGSYSSNPHLLSHPSEPLELVVSGHSGGSSLPPTGPPSTPGLGRYLEVL 445
Query: 141 AGENVT--------LSCSSRSSYDMYHLSREGEAHERRLPAG-----PKVNGTFQADFPL 187
G +V L R H + + + + PAG PK G + P
Sbjct: 446 IGVSVAFVLLLFLLLFLLLRRQRHSKHRTSDQRKTDFQRPAGAAETEPKDRGLLRRSSPA 505
Query: 188 GPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSP-TEPSSKTGNPRHLHI 246
Y ++S D + + +P + P T K +PR
Sbjct: 506 ADVQEENLYAAVKD--------TQSEDRVELDSQQSPHDEDPQAVTYAPVKHSSPRREMA 557
Query: 247 LIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEVTYTQLN 306
+S+ + + D++ +R ++E + + Q+VTY QL+
Sbjct: 558 SPPSSL-----------------SGEFLDTKDRQVEEDRQMDTEAAASEASQDVTYAQLH 600
Query: 307 HCVFTQRKITRPSQRPKTPPTDIIVYTEL 335
++ P + PP + +Y L
Sbjct: 601 SLTLRRKATEPPPSQEGEPPAEPSIYATL 629
>gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 4 [Homo sapiens]
Length = 651
Score = 184 bits (467), Expect = 1e-46
Identities = 130/364 (35%), Positives = 184/364 (50%), Gaps = 44/364 (12%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGMFNDTLRLIG-EHHDGVSK 82
GV +KPSL PG +V EET+ LQC SD + F+L+++G D L+L G + G+S+
Sbjct: 221 GVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGE-RDFLQLAGAQPQAGLSQ 279
Query: 83 ANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDIVIIG-LYEKPSLSAQLGPTVLA 141
ANF++ +++ G YRCYG+ S + SAPSDPLDI+I G Y++ SLS Q GPTV +
Sbjct: 280 ANFTLGPVSRSYGGQYRCYGAHNLSS-EWSAPSDPLDILIAGQFYDRVSLSVQPGPTVAS 338
Query: 142 GENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGTFQADFPLGPAT--HGGTYRCF 199
GENVTL C S+ + L++EG A + + +QA+FP+GP T H GTYRC+
Sbjct: 339 GENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCY 398
Query: 200 GSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGNP-----------------R 242
GS PY + SDPL + V+G PS SPT + T P R
Sbjct: 399 GSQSSKPYLLTHPSDPLELVVSG-PSGGPSSPTTGPTSTSGPEDQPLTPTGSDPQSGLGR 457
Query: 243 HLHILIGTSVVIILFILLFFLL-----HR-----WCSNKKNAAVMDQESA--------GN 284
HL ++IG V +IL +LL LL HR W S ++ A A G
Sbjct: 458 HLGVVIGILVAVILLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGL 517
Query: 285 RTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKV 344
+ +S +D Q +E Y + H Q P + Y E+ ++ R ++
Sbjct: 518 QWRSSPAADAQ--EENLYAAVKHTQPEDGVEMDTRQSPHDEDPQAVTYAEVKHSRPRREM 575
Query: 345 VSCP 348
S P
Sbjct: 576 ASPP 579
Score = 139 bits (349), Expect = 5e-33
Identities = 81/202 (40%), Positives = 116/202 (57%), Gaps = 4/202 (1%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGMFNDTLRLIGEHHD-GVSK 82
G + KP+L A P +V S VILQC S V F+ F L +EG L + H G S+
Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179
Query: 83 ANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDIVIIGLYEKPSLSAQLGPTVLAG 142
A FS+ ++ YRCY ++SPY+ S PSD L+++++G+ +KPSLS Q GP V
Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239
Query: 143 ENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGTFQADFPLGPA--THGGTYRCFG 200
E +TL C S + Y+ + L ++GE +L G QA+F LGP ++GG YRC+G
Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYG 299
Query: 201 SFHDSPYEWSKSSDPLLVSVTG 222
+ H+ EWS SDPL + + G
Sbjct: 300 A-HNLSSEWSAPSDPLDILIAG 320
Score = 119 bits (297), Expect = 5e-27
Identities = 81/226 (35%), Positives = 116/226 (51%), Gaps = 9/226 (3%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
M+ ++ + C+G L G KP+L A PG ++ V L+C + + L
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCY-GSVTHSPYQVSAPSDPLD 119
+RE L + + V K F I +T + AG YRCY GS T S SDPL+
Sbjct: 61 YREK--KTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGR---SESSDPLE 115
Query: 120 IVIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGE-AHERRLPAGPKVN 178
+V+ G Y KP+LSAQ P V +G NV L C S+ ++D + L +EGE H + L + P
Sbjct: 116 LVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHAR 175
Query: 179 GTFQADFPLGPATHGGT--YRCFGSFHDSPYEWSKSSDPLLVSVTG 222
G+ +A F +GP + YRC+ +SPYEWS SD L + V G
Sbjct: 176 GSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLG 221
Score = 30.8 bits (68), Expect = 1.9
Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Query: 278 DQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITR--PSQRPKTPPTDIIVYT 333
D+++ +R ++E + + PQ+VTY QL H + +R+ T PSQ +P I T
Sbjct: 591 DRQAEEDRQMDTEAAASEAPQDVTYAQL-HSLTLRREATEPPPSQEGPSPAVPSIYAT 647
>gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 1 [Homo sapiens]
Length = 650
Score = 184 bits (466), Expect = 1e-46
Identities = 129/364 (35%), Positives = 187/364 (51%), Gaps = 45/364 (12%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGMFNDTLRLIG-EHHDGVSK 82
GV +KPSL PG +V EET+ LQC SD + F+L+++G D L+L G + G+S+
Sbjct: 221 GVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGE-RDFLQLAGAQPQAGLSQ 279
Query: 83 ANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDIVIIG-LYEKPSLSAQLGPTVLA 141
ANF++ +++ G YRCYG+ S + SAPSDPLDI+I G Y++ SLS Q GPTV +
Sbjct: 280 ANFTLGPVSRSYGGQYRCYGAHNLSS-EWSAPSDPLDILIAGQFYDRVSLSVQPGPTVAS 338
Query: 142 GENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGTFQADFPLGPAT--HGGTYRCF 199
GENVTL C S+ + L++EG A + + +QA+FP+GP T H GTYRC+
Sbjct: 339 GENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCY 398
Query: 200 GSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGNP-----------------R 242
GS PY + SDPL + V+G PS SPT + T P R
Sbjct: 399 GSQSSKPYLLTHPSDPLELVVSG-PSGGPSSPTTGPTSTSGPEDQPLTPTGSDPQSGLGR 457
Query: 243 HLHILIGTSVVIILFILLFFLL-----HR-----WCSNKKNAAVMDQESA--------GN 284
HL ++IG V +IL +LL LL HR W S ++ A A G
Sbjct: 458 HLGVVIGILVAVILLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGL 517
Query: 285 RTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKV 344
+ +S +D Q +E Y + H + + ++ P + Y E+ ++ R ++
Sbjct: 518 QWRSSPAADAQ--EENLYAAVKH-TQPEDGVEMDTRSPHDEDPQAVTYAEVKHSRPRREM 574
Query: 345 VSCP 348
S P
Sbjct: 575 ASPP 578
Score = 139 bits (349), Expect = 5e-33
Identities = 81/202 (40%), Positives = 116/202 (57%), Gaps = 4/202 (1%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGMFNDTLRLIGEHHD-GVSK 82
G + KP+L A P +V S VILQC S V F+ F L +EG L + H G S+
Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179
Query: 83 ANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDIVIIGLYEKPSLSAQLGPTVLAG 142
A FS+ ++ YRCY ++SPY+ S PSD L+++++G+ +KPSLS Q GP V
Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239
Query: 143 ENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGTFQADFPLGPA--THGGTYRCFG 200
E +TL C S + Y+ + L ++GE +L G QA+F LGP ++GG YRC+G
Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYG 299
Query: 201 SFHDSPYEWSKSSDPLLVSVTG 222
+ H+ EWS SDPL + + G
Sbjct: 300 A-HNLSSEWSAPSDPLDILIAG 320
Score = 119 bits (297), Expect = 5e-27
Identities = 81/226 (35%), Positives = 116/226 (51%), Gaps = 9/226 (3%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
M+ ++ + C+G L G KP+L A PG ++ V L+C + + L
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCY-GSVTHSPYQVSAPSDPLD 119
+RE L + + V K F I +T + AG YRCY GS T S SDPL+
Sbjct: 61 YREK--KTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGR---SESSDPLE 115
Query: 120 IVIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGE-AHERRLPAGPKVN 178
+V+ G Y KP+LSAQ P V +G NV L C S+ ++D + L +EGE H + L + P
Sbjct: 116 LVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHAR 175
Query: 179 GTFQADFPLGPATHGGT--YRCFGSFHDSPYEWSKSSDPLLVSVTG 222
G+ +A F +GP + YRC+ +SPYEWS SD L + V G
Sbjct: 176 GSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLG 221
Score = 30.8 bits (68), Expect = 1.9
Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Query: 278 DQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITR--PSQRPKTPPTDIIVYT 333
D+++ +R ++E + + PQ+VTY QL H + +R+ T PSQ +P I T
Sbjct: 590 DRQAEEDRQMDTEAAASEAPQDVTYAQL-HSLTLRREATEPPPSQEGPSPAVPSIYAT 646
>gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 2 [Homo sapiens]
Length = 652
Score = 183 bits (464), Expect = 2e-46
Identities = 129/364 (35%), Positives = 186/364 (51%), Gaps = 43/364 (11%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGMFNDTLRLIG-EHHDGVSK 82
GV +KPSL PG +V EET+ LQC SD + F+L+++G D L+L G + G+S+
Sbjct: 221 GVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGE-RDFLQLAGAQPQAGLSQ 279
Query: 83 ANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDIVIIG-LYEKPSLSAQLGPTVLA 141
ANF++ +++ G YRCYG+ S + SAPSDPLDI+I G Y++ SLS Q GPTV +
Sbjct: 280 ANFTLGPVSRSYGGQYRCYGAHNLSS-EWSAPSDPLDILIAGQFYDRVSLSVQPGPTVAS 338
Query: 142 GENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGTFQADFPLGPAT--HGGTYRCF 199
GENVTL C S+ + L++EG A + + +QA+FP+GP T H GTYRC+
Sbjct: 339 GENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCY 398
Query: 200 GSFHDSPYEWSKSSDPLLVSV---TGNPSNSWPSPTEPSS--------------KTGNPR 242
GS PY + SDPL + V +G PS+ PT S+ ++G R
Sbjct: 399 GSQSSKPYLLTHPSDPLELVVSGPSGGPSSPTTGPTSTSAGPEDQPLTPTGSDPQSGLGR 458
Query: 243 HLHILIGTSVVIILFILLFFLL-----HR-----WCSNKKNAAVMDQESA--------GN 284
HL ++IG V +IL +LL LL HR W S ++ A A G
Sbjct: 459 HLGVVIGILVAVILLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGL 518
Query: 285 RTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKV 344
+ +S +D Q +E Y + H Q P + Y E+ ++ R ++
Sbjct: 519 QWRSSPAADAQ--EENLYAAVKHTQPEDGVEMDTRQSPHDEDPQAVTYAEVKHSRPRREM 576
Query: 345 VSCP 348
S P
Sbjct: 577 ASPP 580
Score = 139 bits (349), Expect = 5e-33
Identities = 81/202 (40%), Positives = 116/202 (57%), Gaps = 4/202 (1%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGMFNDTLRLIGEHHD-GVSK 82
G + KP+L A P +V S VILQC S V F+ F L +EG L + H G S+
Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179
Query: 83 ANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDIVIIGLYEKPSLSAQLGPTVLAG 142
A FS+ ++ YRCY ++SPY+ S PSD L+++++G+ +KPSLS Q GP V
Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239
Query: 143 ENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGTFQADFPLGPA--THGGTYRCFG 200
E +TL C S + Y+ + L ++GE +L G QA+F LGP ++GG YRC+G
Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYG 299
Query: 201 SFHDSPYEWSKSSDPLLVSVTG 222
+ H+ EWS SDPL + + G
Sbjct: 300 A-HNLSSEWSAPSDPLDILIAG 320
Score = 119 bits (297), Expect = 5e-27
Identities = 81/226 (35%), Positives = 116/226 (51%), Gaps = 9/226 (3%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
M+ ++ + C+G L G KP+L A PG ++ V L+C + + L
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCY-GSVTHSPYQVSAPSDPLD 119
+RE L + + V K F I +T + AG YRCY GS T S SDPL+
Sbjct: 61 YREK--KTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGR---SESSDPLE 115
Query: 120 IVIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGE-AHERRLPAGPKVN 178
+V+ G Y KP+LSAQ P V +G NV L C S+ ++D + L +EGE H + L + P
Sbjct: 116 LVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHAR 175
Query: 179 GTFQADFPLGPATHGGT--YRCFGSFHDSPYEWSKSSDPLLVSVTG 222
G+ +A F +GP + YRC+ +SPYEWS SD L + V G
Sbjct: 176 GSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLG 221
Score = 30.8 bits (68), Expect = 1.9
Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Query: 278 DQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITR--PSQRPKTPPTDIIVYT 333
D+++ +R ++E + + PQ+VTY QL H + +R+ T PSQ +P I T
Sbjct: 592 DRQAEEDRQMDTEAAASEAPQDVTYAQL-HSLTLRREATEPPPSQEGPSPAVPSIYAT 648
>gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 3 [Homo sapiens]
Length = 651
Score = 182 bits (463), Expect = 3e-46
Identities = 128/364 (35%), Positives = 189/364 (51%), Gaps = 44/364 (12%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGMFNDTLRLIG-EHHDGVSK 82
GV +KPSL PG +V EET+ LQC SD + F+L+++G D L+L G + G+S+
Sbjct: 221 GVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGE-RDFLQLAGAQPQAGLSQ 279
Query: 83 ANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDIVIIG-LYEKPSLSAQLGPTVLA 141
ANF++ +++ G YRCYG+ S + SAPSDPLDI+I G Y++ SLS Q GPTV +
Sbjct: 280 ANFTLGPVSRSYGGQYRCYGAHNLSS-EWSAPSDPLDILIAGQFYDRVSLSVQPGPTVAS 338
Query: 142 GENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGTFQADFPLGPAT--HGGTYRCF 199
GENVTL C S+ + L++EG A + + +QA+FP+GP T H GTYRC+
Sbjct: 339 GENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCY 398
Query: 200 GSFHDSPYEWSKSSDPLLVSV---TGNPSNSWPSPTEPSS--------------KTGNPR 242
GS PY + SDPL + V +G PS+ PT S+ ++G R
Sbjct: 399 GSQSSKPYLLTHPSDPLELVVSGPSGGPSSPTTGPTSTSAGPEDQPLTPTGSDPQSGLGR 458
Query: 243 HLHILIGTSVVIILFILLFFLL-----HR-----WCSNKKNAAVMDQESA--------GN 284
HL ++IG V +IL +LL LL HR W S ++ A A G
Sbjct: 459 HLGVVIGILVAVILLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGL 518
Query: 285 RTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKV 344
+ +S +D Q +E Y + H + + ++ P + Y E+ ++ R ++
Sbjct: 519 QWRSSPAADAQ--EENLYAAVKH-TQPEDGVEMDTRSPHDEDPQAVTYAEVKHSRPRREM 575
Query: 345 VSCP 348
S P
Sbjct: 576 ASPP 579
Score = 139 bits (349), Expect = 5e-33
Identities = 81/202 (40%), Positives = 116/202 (57%), Gaps = 4/202 (1%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGMFNDTLRLIGEHHD-GVSK 82
G + KP+L A P +V S VILQC S V F+ F L +EG L + H G S+
Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179
Query: 83 ANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDIVIIGLYEKPSLSAQLGPTVLAG 142
A FS+ ++ YRCY ++SPY+ S PSD L+++++G+ +KPSLS Q GP V
Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239
Query: 143 ENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGTFQADFPLGPA--THGGTYRCFG 200
E +TL C S + Y+ + L ++GE +L G QA+F LGP ++GG YRC+G
Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYG 299
Query: 201 SFHDSPYEWSKSSDPLLVSVTG 222
+ H+ EWS SDPL + + G
Sbjct: 300 A-HNLSSEWSAPSDPLDILIAG 320
Score = 119 bits (297), Expect = 5e-27
Identities = 81/226 (35%), Positives = 116/226 (51%), Gaps = 9/226 (3%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
M+ ++ + C+G L G KP+L A PG ++ V L+C + + L
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCY-GSVTHSPYQVSAPSDPLD 119
+RE L + + V K F I +T + AG YRCY GS T S SDPL+
Sbjct: 61 YREK--KTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGR---SESSDPLE 115
Query: 120 IVIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGE-AHERRLPAGPKVN 178
+V+ G Y KP+LSAQ P V +G NV L C S+ ++D + L +EGE H + L + P
Sbjct: 116 LVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHAR 175
Query: 179 GTFQADFPLGPATHGGT--YRCFGSFHDSPYEWSKSSDPLLVSVTG 222
G+ +A F +GP + YRC+ +SPYEWS SD L + V G
Sbjct: 176 GSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLG 221
Score = 30.8 bits (68), Expect = 1.9
Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Query: 278 DQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITR--PSQRPKTPPTDIIVYT 333
D+++ +R ++E + + PQ+VTY QL H + +R+ T PSQ +P I T
Sbjct: 591 DRQAEEDRQMDTEAAASEAPQDVTYAQL-HSLTLRREATEPPPSQEGPSPAVPSIYAT 647
>gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B,
member 2 isoform 1 [Homo sapiens]
Length = 598
Score = 180 bits (456), Expect = 2e-45
Identities = 132/382 (34%), Positives = 184/382 (48%), Gaps = 76/382 (19%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGMFNDTLRLIGEHHD-GVSK 82
GV +KPSL PG +V E++ LQC SDV ++ F+L++EG D +L G G+S+
Sbjct: 220 GVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVLYKEGE-RDLRQLPGRQPQAGLSQ 278
Query: 83 ANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDIVIIG-LYEKPSLSAQLGPTVLA 141
ANF++ +++ G YRCYG+ S + SAPSDPLDI+I G + P +S Q GPTV +
Sbjct: 279 ANFTLGPVSRSYGGQYRCYGAHNLSS-ECSAPSDPLDILITGQIRGTPFISVQPGPTVAS 337
Query: 142 GENVTLSCSSRSSYDMYHLSREGEAHE----RRLPAGPKVNGTFQADFPLGPAT--HGGT 195
GENVTL C S + + L++ G A R + PK +QA+FP+ P T H GT
Sbjct: 338 GENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPK----YQAEFPMSPVTSAHAGT 393
Query: 196 YRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGNP-------------- 241
YRC+GS + PY S S+PL + V+G S P PT P S P
Sbjct: 394 YRCYGSLNSDPYLLSHPSEPLELVVSGPSMGSSPPPTGPISTPAGPEDQPLTPTGSDPQS 453
Query: 242 ---RHLHILIGTSVVIILFILLFFLL-----HR-----WCSNKKNA-------------- 274
RHL ++IG V ++L +LL LL HR W S ++ A
Sbjct: 454 GLGRHLGVVIGILVAVVLLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPT 513
Query: 275 ----------AVMDQES---AGNRTANSEDSDEQD--------PQEVTYTQLNHCVFTQR 313
A QE A + ED E D PQ+VTY QL+ ++
Sbjct: 514 DRGLQWRSSPAADAQEENLYAAVKDTQPEDGVEMDTRAAASEAPQDVTYAQLHSLTLRRK 573
Query: 314 KITRPSQRPKTPPTDIIVYTEL 335
P + + PP + +Y L
Sbjct: 574 ATEPPPSQEREPPAEPSIYATL 595
Score = 142 bits (358), Expect = 4e-34
Identities = 85/202 (42%), Positives = 119/202 (58%), Gaps = 4/202 (1%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGMFNDTLRLIGEHHD-GVSK 82
G + KP+L A P +V S V LQC S V F F+L +EG L + H G S+
Sbjct: 119 GAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSR 178
Query: 83 ANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDIVIIGLYEKPSLSAQLGPTVLAG 142
A FS+ ++ + ++RCYG +SPY S+PSD L++++ G+ +KPSLS Q GP V G
Sbjct: 179 AIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPG 238
Query: 143 ENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGTFQADFPLGPA--THGGTYRCFG 200
E++TL C S YD + L +EGE R+LP G QA+F LGP ++GG YRC+G
Sbjct: 239 ESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCYG 298
Query: 201 SFHDSPYEWSKSSDPLLVSVTG 222
+ H+ E S SDPL + +TG
Sbjct: 299 A-HNLSSECSAPSDPLDILITG 319
Score = 104 bits (259), Expect = 1e-22
Identities = 73/225 (32%), Positives = 110/225 (48%), Gaps = 8/225 (3%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
M+ +V + C+G L G KP+L A P ++ V L C + + + L
Sbjct: 1 MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRL 60
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120
+RE + I + V F I +T + G Y C +S + S SDPL +
Sbjct: 61 YREKKSASWITRI--RPELVKNGQFHIPSITWEHTGRYGCQ---YYSRARWSELSDPLVL 115
Query: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREG-EAHERRLPAGPKVNG 179
V+ G Y KP+LSAQ P V +G VTL C S+ ++ + L +EG E H + L + P G
Sbjct: 116 VMTGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARG 175
Query: 180 TFQADFPLGPAT--HGGTYRCFGSFHDSPYEWSKSSDPLLVSVTG 222
+ +A F +GP + ++RC+G +SPY WS SD L + V G
Sbjct: 176 SSRAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPG 220
>gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B,
member 2 isoform 2 [Homo sapiens]
Length = 597
Score = 179 bits (455), Expect = 3e-45
Identities = 132/381 (34%), Positives = 186/381 (48%), Gaps = 75/381 (19%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGMFNDTLRLIGEHHD-GVSK 82
GV +KPSL PG +V E++ LQC SDV ++ F+L++EG D +L G G+S+
Sbjct: 220 GVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVLYKEGE-RDLRQLPGRQPQAGLSQ 278
Query: 83 ANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDIVIIG-LYEKPSLSAQLGPTVLA 141
ANF++ +++ G YRCYG+ S + SAPSDPLDI+I G + P +S Q GPTV +
Sbjct: 279 ANFTLGPVSRSYGGQYRCYGAHNLSS-ECSAPSDPLDILITGQIRGTPFISVQPGPTVAS 337
Query: 142 GENVTLSCSSRSSYDMYHLSREGEAHE----RRLPAGPKVNGTFQADFPLGPAT--HGGT 195
GENVTL C S + + L++ G A R + PK +QA+FP+ P T H GT
Sbjct: 338 GENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPK----YQAEFPMSPVTSAHAGT 393
Query: 196 YRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSS----------------KTG 239
YRC+GS + PY S S+PL + V+G S P PT P S ++G
Sbjct: 394 YRCYGSLNSDPYLLSHPSEPLELVVSGPSMGSSPPPTGPISTPGPEDQPLTPTGSDPQSG 453
Query: 240 NPRHLHILIGTSVVIILFILLFFLL-----HR-----WCSNKKNA--------------- 274
RHL ++IG V ++L +LL LL HR W S ++ A
Sbjct: 454 LGRHLGVVIGILVAVVLLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTD 513
Query: 275 ---------AVMDQES---AGNRTANSEDSDEQD--------PQEVTYTQLNHCVFTQRK 314
A QE A + ED E D PQ+VTY QL+ ++
Sbjct: 514 RGLQWRSSPAADAQEENLYAAVKDTQPEDGVEMDTRAAASEAPQDVTYAQLHSLTLRRKA 573
Query: 315 ITRPSQRPKTPPTDIIVYTEL 335
P + + PP + +Y L
Sbjct: 574 TEPPPSQEREPPAEPSIYATL 594
Score = 142 bits (358), Expect = 4e-34
Identities = 85/202 (42%), Positives = 119/202 (58%), Gaps = 4/202 (1%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGMFNDTLRLIGEHHD-GVSK 82
G + KP+L A P +V S V LQC S V F F+L +EG L + H G S+
Sbjct: 119 GAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSR 178
Query: 83 ANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDIVIIGLYEKPSLSAQLGPTVLAG 142
A FS+ ++ + ++RCYG +SPY S+PSD L++++ G+ +KPSLS Q GP V G
Sbjct: 179 AIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPG 238
Query: 143 ENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGTFQADFPLGPA--THGGTYRCFG 200
E++TL C S YD + L +EGE R+LP G QA+F LGP ++GG YRC+G
Sbjct: 239 ESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCYG 298
Query: 201 SFHDSPYEWSKSSDPLLVSVTG 222
+ H+ E S SDPL + +TG
Sbjct: 299 A-HNLSSECSAPSDPLDILITG 319
Score = 104 bits (259), Expect = 1e-22
Identities = 73/225 (32%), Positives = 110/225 (48%), Gaps = 8/225 (3%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
M+ +V + C+G L G KP+L A P ++ V L C + + + L
Sbjct: 1 MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRL 60
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120
+RE + I + V F I +T + G Y C +S + S SDPL +
Sbjct: 61 YREKKSASWITRI--RPELVKNGQFHIPSITWEHTGRYGCQ---YYSRARWSELSDPLVL 115
Query: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREG-EAHERRLPAGPKVNG 179
V+ G Y KP+LSAQ P V +G VTL C S+ ++ + L +EG E H + L + P G
Sbjct: 116 VMTGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARG 175
Query: 180 TFQADFPLGPAT--HGGTYRCFGSFHDSPYEWSKSSDPLLVSVTG 222
+ +A F +GP + ++RC+G +SPY WS SD L + V G
Sbjct: 176 SSRAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPG 220
>gi|125987593 leukocyte immunoglobulin-like receptor, subfamily B,
member 5 isoform 3 [Homo sapiens]
Length = 491
Score = 173 bits (439), Expect = 2e-43
Identities = 126/372 (33%), Positives = 184/372 (49%), Gaps = 62/372 (16%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGMFNDTLRLIGEHHD-GVSK 82
GV RKPSLL G +V ++ LQC SDV ++ F+L++EG +D ++ G+ G+S+
Sbjct: 119 GVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGE-HDLVQGSGQQPQAGLSQ 177
Query: 83 ANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDIVIIGLY-EKPSLSAQLGPTVLA 141
ANF++ +++ G YRCYG+ SP + SAPSDPLDI+I GL + P+LS Q GP V +
Sbjct: 178 ANFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVAS 236
Query: 142 GENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGTFQADFPLGPAT--HGGTYRCF 199
GENVTL C S D + L++EG AH + QA+F + P T GGTYRC+
Sbjct: 237 GENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCY 296
Query: 200 GSFHDSPYEWSKSSDPLLVSVTG-------NPSNSWPSPTEPSS----------KTGNPR 242
+ PY S S P + V+G +P+ S P+P P ++G R
Sbjct: 297 SAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLGR 356
Query: 243 HLHILIGTSV--VIILFILLFFLL-HRWCSNKK--------------------------- 272
HL ++ G SV V++LF+LLF LL HR S +
Sbjct: 357 HLGVVTGVSVAFVLLLFLLLFLLLRHRHQSKHRTSAHFYRPAGAAGPEPKDQGLQKRASP 416
Query: 273 ---------NAAVMDQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPK 323
NAAV D + ++ + + PQ+VTY QL+ + P + +
Sbjct: 417 VADIQEEILNAAVKDTQPKDGVEMDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQER 476
Query: 324 TPPTDIIVYTEL 335
PP + +Y L
Sbjct: 477 EPPAEPSIYAPL 488
Score = 117 bits (294), Expect = 1e-26
Identities = 83/250 (33%), Positives = 123/250 (49%), Gaps = 10/250 (4%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
M+L + + C+G + G KP+L A P ++ + V L C + E + L
Sbjct: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120
+EG+ R + +KA F I D AG YRCY +P S PSDPL++
Sbjct: 61 DKEGL--PWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCY---YETPAGWSEPSDPLEL 115
Query: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVN-G 179
V G+ KPSL G V G ++TL C S YD++ L +EGE H+ +G + G
Sbjct: 116 VATGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGE-HDLVQGSGQQPQAG 174
Query: 180 TFQADFPLGPA--THGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSK 237
QA+F LGP +HGG YRC+G+ + SP WS SDPL + + G + +P K
Sbjct: 175 LSQANFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPK 233
Query: 238 TGNPRHLHIL 247
+ ++ +L
Sbjct: 234 VASGENVTLL 243
>gi|125987591 leukocyte immunoglobulin-like receptor, subfamily B,
member 5 isoform 1 [Homo sapiens]
Length = 591
Score = 173 bits (439), Expect = 2e-43
Identities = 126/372 (33%), Positives = 183/372 (49%), Gaps = 62/372 (16%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGMFNDTLRLIGEHHD-GVSK 82
GV RKPSLL G +V ++ LQC SDV ++ F+L++EG +D ++ G+ G+S+
Sbjct: 219 GVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGE-HDLVQGSGQQPQAGLSQ 277
Query: 83 ANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDIVIIGLY-EKPSLSAQLGPTVLA 141
ANF++ +++ G YRCYG+ SP + SAPSDPLDI+I GL + P+LS Q GP V +
Sbjct: 278 ANFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVAS 336
Query: 142 GENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGTFQADFPLGPAT--HGGTYRCF 199
GENVTL C S D + L++EG AH + QA+F + P T GGTYRC+
Sbjct: 337 GENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCY 396
Query: 200 GSFHDSPYEWSKSSDPLLVSVTG-------NPSNSWPSPTEPSSKTGNP----------R 242
+ PY S S P + V+G +P+ S P+P P + P R
Sbjct: 397 SAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLGR 456
Query: 243 HLHILIGTSV--VIILFILLFFLL-HRWCSNKK--------------------------- 272
HL ++ G SV V++LF+LLF LL HR S +
Sbjct: 457 HLGVVTGVSVAFVLLLFLLLFLLLRHRHQSKHRTSAHFYRPAGAAGPEPKDQGLQKRASP 516
Query: 273 ---------NAAVMDQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPK 323
NAAV D + ++ + + PQ+VTY QL+ + P + +
Sbjct: 517 VADIQEEILNAAVKDTQPKDGVEMDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQER 576
Query: 324 TPPTDIIVYTEL 335
PP + +Y L
Sbjct: 577 EPPAEPSIYAPL 588
Score = 107 bits (267), Expect = 2e-23
Identities = 78/228 (34%), Positives = 116/228 (50%), Gaps = 7/228 (3%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWS-DVMFEHFLLHREGMFNDTLRLIGEHHDGVSK 82
G + +P+LLA P +V S V LQC + D + L+ E TL + G S+
Sbjct: 119 GFYAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTL-YSQKLPKGPSQ 177
Query: 83 ANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDIVIIGLYEKPSLSAQLGPTVLAG 142
A F + +T +RCY +P S PSD L+I++ G+ KPSL G V G
Sbjct: 178 ALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARG 237
Query: 143 ENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVN-GTFQADFPLGPA--THGGTYRCF 199
++TL C S YD++ L +EGE H+ +G + G QA+F LGP +HGG YRC+
Sbjct: 238 GSLTLQCRSDVGYDIFVLYKEGE-HDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCY 296
Query: 200 GSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGNPRHLHIL 247
G+ + SP WS SDPL + + G + +P K + ++ +L
Sbjct: 297 GAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLL 343
Score = 102 bits (254), Expect = 5e-22
Identities = 72/224 (32%), Positives = 103/224 (45%), Gaps = 7/224 (3%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
M+L + + C+G + G KP+L A P ++ + V L C + E + L
Sbjct: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120
+EG+ R + +KA F I D AG YRCY +P S PSDPL++
Sbjct: 61 DKEGL--PWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCY---YETPAGWSEPSDPLEL 115
Query: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGT 180
V G Y +P+L A P V +G NVTL C + + L E + R L + G
Sbjct: 116 VATGFYAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGP 175
Query: 181 FQADFPLGPATHG--GTYRCFGSFHDSPYEWSKSSDPLLVSVTG 222
QA FP+GP T +RC+ + +P WS SD L + V G
Sbjct: 176 SQALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPG 219
>gi|5803070 leukocyte immunoglobulin-like receptor, subfamily B,
member 5 isoform 2 [Homo sapiens]
Length = 590
Score = 172 bits (435), Expect = 5e-43
Identities = 128/371 (34%), Positives = 187/371 (50%), Gaps = 61/371 (16%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGMFNDTLRLIGEHHD-GVSK 82
GV RKPSLL G +V ++ LQC SDV ++ F+L++EG +D ++ G+ G+S+
Sbjct: 219 GVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGE-HDLVQGSGQQPQAGLSQ 277
Query: 83 ANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDIVIIGLY-EKPSLSAQLGPTVLA 141
ANF++ +++ G YRCYG+ SP + SAPSDPLDI+I GL + P+LS Q GP V +
Sbjct: 278 ANFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVAS 336
Query: 142 GENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGTFQADFPLGPAT--HGGTYRCF 199
GENVTL C S D + L++EG AH + QA+F + P T GGTYRC+
Sbjct: 337 GENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCY 396
Query: 200 GSFHDSPYEWSKSSDPLLVSVTG-------NPSNSWPSP---TEPSSKTG-NP-----RH 243
+ PY S S P + V+G +P+ S P+P +P + TG +P RH
Sbjct: 397 SAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPGPEDQPLTPTGLDPQSGLGRH 456
Query: 244 LHILIGTSV--VIILFILLFFLL-HRWCSNKK---------------------------- 272
L ++ G SV V++LF+LLF LL HR S +
Sbjct: 457 LGVVTGVSVAFVLLLFLLLFLLLRHRHQSKHRTSAHFYRPAGAAGPEPKDQGLQKRASPV 516
Query: 273 --------NAAVMDQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKT 324
NAAV D + ++ + + PQ+VTY QL+ + P + +
Sbjct: 517 ADIQEEILNAAVKDTQPKDGVEMDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQERE 576
Query: 325 PPTDIIVYTEL 335
PP + +Y L
Sbjct: 577 PPAEPSIYAPL 587
Score = 107 bits (267), Expect = 2e-23
Identities = 78/228 (34%), Positives = 116/228 (50%), Gaps = 7/228 (3%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWS-DVMFEHFLLHREGMFNDTLRLIGEHHDGVSK 82
G + +P+LLA P +V S V LQC + D + L+ E TL + G S+
Sbjct: 119 GFYAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTL-YSQKLPKGPSQ 177
Query: 83 ANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDIVIIGLYEKPSLSAQLGPTVLAG 142
A F + +T +RCY +P S PSD L+I++ G+ KPSL G V G
Sbjct: 178 ALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARG 237
Query: 143 ENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVN-GTFQADFPLGPA--THGGTYRCF 199
++TL C S YD++ L +EGE H+ +G + G QA+F LGP +HGG YRC+
Sbjct: 238 GSLTLQCRSDVGYDIFVLYKEGE-HDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCY 296
Query: 200 GSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGNPRHLHIL 247
G+ + SP WS SDPL + + G + +P K + ++ +L
Sbjct: 297 GAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLL 343
Score = 102 bits (254), Expect = 5e-22
Identities = 72/224 (32%), Positives = 103/224 (45%), Gaps = 7/224 (3%)
Query: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
M+L + + C+G + G KP+L A P ++ + V L C + E + L
Sbjct: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
Query: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120
+EG+ R + +KA F I D AG YRCY +P S PSDPL++
Sbjct: 61 DKEGL--PWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCY---YETPAGWSEPSDPLEL 115
Query: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGT 180
V G Y +P+L A P V +G NVTL C + + L E + R L + G
Sbjct: 116 VATGFYAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGP 175
Query: 181 FQADFPLGPATHG--GTYRCFGSFHDSPYEWSKSSDPLLVSVTG 222
QA FP+GP T +RC+ + +P WS SD L + V G
Sbjct: 176 SQALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPG 219
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,067,331
Number of Sequences: 37866
Number of extensions: 735176
Number of successful extensions: 2898
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 76
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 2216
Number of HSP's gapped (non-prelim): 249
length of query: 348
length of database: 18,247,518
effective HSP length: 103
effective length of query: 245
effective length of database: 14,347,320
effective search space: 3515093400
effective search space used: 3515093400
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.