Search of human proteins with 16418453

Search of human proteins with 16418453

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|16418453 pannexin 3 [Homo sapiens]
         (392 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|16418453 pannexin 3 [Homo sapiens]                                 781   0.0  
gi|39995064 pannexin 1 [Homo sapiens]                                 273   2e-73
gi|163659920 pannexin 2 isoform 1 [Homo sapiens]                      144   1e-34
gi|237757297 pannexin 2 isoform 2 [Homo sapiens]                      144   1e-34
gi|197276594 RNA binding motif protein 20 [Homo sapiens]               30   4.9  
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    29   6.4  
gi|55742693 zyg-11 homolog B [Homo sapiens]                            29   8.4  

>gi|16418453 pannexin 3 [Homo sapiens]
          Length = 392

 Score =  781 bits (2017), Expect = 0.0
 Identities = 392/392 (100%), Positives = 392/392 (100%)

Query: 1   MSLAHTAAEYMLSDALLPDRRGPRLKGLRLELPLDRIVKFVAVGSPLLLMSLAFAQEFSS 60
           MSLAHTAAEYMLSDALLPDRRGPRLKGLRLELPLDRIVKFVAVGSPLLLMSLAFAQEFSS
Sbjct: 1   MSLAHTAAEYMLSDALLPDRRGPRLKGLRLELPLDRIVKFVAVGSPLLLMSLAFAQEFSS 60

Query: 61  GSPISCFSPSNFSIRQAAYVDSSCWDSLLHHKQDGPGQDKMKSLWPHKALPYSLLALALL 120
           GSPISCFSPSNFSIRQAAYVDSSCWDSLLHHKQDGPGQDKMKSLWPHKALPYSLLALALL
Sbjct: 61  GSPISCFSPSNFSIRQAAYVDSSCWDSLLHHKQDGPGQDKMKSLWPHKALPYSLLALALL 120

Query: 121 MYLPVLLWQYAAVPALSSDLLFIISELDKSYNRSIRLVQHMLKIRQKSSDPYVFWNELEK 180
           MYLPVLLWQYAAVPALSSDLLFIISELDKSYNRSIRLVQHMLKIRQKSSDPYVFWNELEK
Sbjct: 121 MYLPVLLWQYAAVPALSSDLLFIISELDKSYNRSIRLVQHMLKIRQKSSDPYVFWNELEK 180

Query: 181 ARKERYFEFPLLERYLACKQRSHSLVATYLLRNSLLLIFTSATYLYLGHFHLDVFFQEEF 240
           ARKERYFEFPLLERYLACKQRSHSLVATYLLRNSLLLIFTSATYLYLGHFHLDVFFQEEF
Sbjct: 181 ARKERYFEFPLLERYLACKQRSHSLVATYLLRNSLLLIFTSATYLYLGHFHLDVFFQEEF 240

Query: 241 SCSIKTGLLSDETHVPNLITCRLTSLSIFQIVSLSSVAIYTILVPVIIYNLTRLCRWDKR 300
           SCSIKTGLLSDETHVPNLITCRLTSLSIFQIVSLSSVAIYTILVPVIIYNLTRLCRWDKR
Sbjct: 241 SCSIKTGLLSDETHVPNLITCRLTSLSIFQIVSLSSVAIYTILVPVIIYNLTRLCRWDKR 300

Query: 301 LLSVYEMLPAFDLLSRKMLGCPINDLNVILLFLRANISELISFSWLSVLCVLKDTTTQKH 360
           LLSVYEMLPAFDLLSRKMLGCPINDLNVILLFLRANISELISFSWLSVLCVLKDTTTQKH
Sbjct: 301 LLSVYEMLPAFDLLSRKMLGCPINDLNVILLFLRANISELISFSWLSVLCVLKDTTTQKH 360

Query: 361 NIDTVVDFMTLLAGLEPSKPKHLTNSACDEHP 392
           NIDTVVDFMTLLAGLEPSKPKHLTNSACDEHP
Sbjct: 361 NIDTVVDFMTLLAGLEPSKPKHLTNSACDEHP 392


>gi|39995064 pannexin 1 [Homo sapiens]
          Length = 426

 Score =  273 bits (698), Expect = 2e-73
 Identities = 154/360 (42%), Positives = 225/360 (62%), Gaps = 8/360 (2%)

Query: 1   MSLAHTAAEYMLSDALLPDRRGPRLKGLRLELPLDRIVKFVAVGSPLLLMSLAFAQEFSS 60
           M++A  A EY+ SD LL +   P+ KGLRLEL +D++V  +AVG PLLL+SLAFAQE S 
Sbjct: 1   MAIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISI 60

Query: 61  GSPISCFSPSNFSIRQAAYVDSSCWDSLLHHKQDGPGQDKMKSLWPHKALPYSLLALALL 120
           G+ ISCFSPS+FS RQAA+VDS CW + +  K     +     LW HK  PY LL  A+L
Sbjct: 61  GTQISCFSPSSFSWRQAAFVDSYCW-AAVQQKNSLQSESGNLPLWLHKFFPYILLLFAIL 119

Query: 121 MYLPVLLWQYAAVPALSSDLLFIISELDKSYNRSIRLVQHMLKIRQKS---SDPYVFWNE 177
           +YLP L W++AA P + SDL FI+ ELDK YNR+I+  +    +  +    S P V  N 
Sbjct: 120 LYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSARDLDMRDGACSVPGVTENL 179

Query: 178 LEKARK--ERYFEFPLLERYLACKQRSHSLVATYLLRNSLLLIFTSATYLYLGHFHLDVF 235
            +   +  E +F++P++E+YL  K+ S++L+  Y+    L LI      +YLG++     
Sbjct: 180 GQSLWEVSESHFKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSS 239

Query: 236 FQEEFSCSIKTGLLSDETHVPNLITCRLTSLSIFQIVSLSSVAIYTILVPVIIYNLTRLC 295
             +EF CSIK+G+L +++ VP+   C+L ++ IFQ++S+ ++ +Y +L PV++Y L    
Sbjct: 240 LSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPF 299

Query: 296 RWDKRLLSVYEMLPAFDLLSRKMLGCPINDLNVILLFLRANISELISFSWLSVLCVLKDT 355
           R    +L VYE+LP FD+L  K  G   NDL++  LFL  NISE+ S+  L VL  +K +
Sbjct: 300 RQKTDVLKVYEILPTFDVLHFKSEG--YNDLSLYNLFLEENISEVKSYKCLKVLENIKSS 357


>gi|163659920 pannexin 2 isoform 1 [Homo sapiens]
          Length = 677

 Score =  144 bits (363), Expect = 1e-34
 Identities = 101/332 (30%), Positives = 173/332 (52%), Gaps = 18/332 (5%)

Query: 28  LRLELPLDRIVKFVAVGSPLLLMSLAFAQEFSSGSPISCFSPSNFSIRQAAYVDSSCWDS 87
           L+LELP DR+V    V  P+LL++L F + F+   PI C++P NF+  QA Y    CW  
Sbjct: 44  LKLELPFDRVVTIGTVLVPILLVTLVFTKNFAE-EPIYCYTPHNFTRDQALYARGYCWTE 102

Query: 88  LLHHKQDGPGQDKMKSLWP----HKALPYSLLALALLMYLPVLLWQYAAVPALSSDLLFI 143
           L   +   PG D   SLWP    HK LPY+LLA A +MY+P L W++ A   L+S+L F+
Sbjct: 103 L---RDALPGVDA--SLWPSLFEHKFLPYALLAFAAIMYVPALGWEFLASTRLTSELNFL 157

Query: 144 ISELDKSYNRSIRLVQHMLKIRQKSSDPYVFWNE----LEKARKERYFEFPLLERYLACK 199
           + E+D  Y+R+       ++ + +S  P +   E    +E A KE+  E  L E+YL  +
Sbjct: 158 LQEIDNCYHRAAEGRAPKIEKQIQSKGPGITEREKREIIENAEKEKSPEQNLFEKYLERR 217

Query: 200 QRSHSLVATYLLRNSLLLIFTSATYLYLGHFHLDVFFQEEFSCSIKTGLLSDETHVPNL- 258
            RS+ L   YL R+ L+L+ ++    YL  ++     Q EF+C++           P + 
Sbjct: 218 GRSNFLAKLYLARHVLILLLSAVPISYLCTYYA-TQKQNEFTCALGASPDGAAGAGPAVR 276

Query: 259 ITCRLTSLSIFQIVSLSSVAIYTILVPVIIYNLTRLCRWDKRLLSVYEMLPAFDLLSRKM 318
           ++C+L S+ + +I++   + +  ++  +I+ NL  L  + K    +++ L    + +R+ 
Sbjct: 277 VSCKLPSVQLQRIIAGVDIVLLCVMNLIILVNLIHLFIFRKSNF-IFDKLHKVGIKTRRQ 335

Query: 319 -LGCPINDLNVILLFLRANISELISFSWLSVL 349
                  D+N++ +F   N   + S + L  +
Sbjct: 336 WRRSQFCDINILAMFCNENRDHIKSLNRLDFI 367


>gi|237757297 pannexin 2 isoform 2 [Homo sapiens]
          Length = 643

 Score =  144 bits (363), Expect = 1e-34
 Identities = 101/332 (30%), Positives = 173/332 (52%), Gaps = 18/332 (5%)

Query: 28  LRLELPLDRIVKFVAVGSPLLLMSLAFAQEFSSGSPISCFSPSNFSIRQAAYVDSSCWDS 87
           L+LELP DR+V    V  P+LL++L F + F+   PI C++P NF+  QA Y    CW  
Sbjct: 44  LKLELPFDRVVTIGTVLVPILLVTLVFTKNFAE-EPIYCYTPHNFTRDQALYARGYCWTE 102

Query: 88  LLHHKQDGPGQDKMKSLWP----HKALPYSLLALALLMYLPVLLWQYAAVPALSSDLLFI 143
           L   +   PG D   SLWP    HK LPY+LLA A +MY+P L W++ A   L+S+L F+
Sbjct: 103 L---RDALPGVDA--SLWPSLFEHKFLPYALLAFAAIMYVPALGWEFLASTRLTSELNFL 157

Query: 144 ISELDKSYNRSIRLVQHMLKIRQKSSDPYVFWNE----LEKARKERYFEFPLLERYLACK 199
           + E+D  Y+R+       ++ + +S  P +   E    +E A KE+  E  L E+YL  +
Sbjct: 158 LQEIDNCYHRAAEGRAPKIEKQIQSKGPGITEREKREIIENAEKEKSPEQNLFEKYLERR 217

Query: 200 QRSHSLVATYLLRNSLLLIFTSATYLYLGHFHLDVFFQEEFSCSIKTGLLSDETHVPNL- 258
            RS+ L   YL R+ L+L+ ++    YL  ++     Q EF+C++           P + 
Sbjct: 218 GRSNFLAKLYLARHVLILLLSAVPISYLCTYYA-TQKQNEFTCALGASPDGAAGAGPAVR 276

Query: 259 ITCRLTSLSIFQIVSLSSVAIYTILVPVIIYNLTRLCRWDKRLLSVYEMLPAFDLLSRKM 318
           ++C+L S+ + +I++   + +  ++  +I+ NL  L  + K    +++ L    + +R+ 
Sbjct: 277 VSCKLPSVQLQRIIAGVDIVLLCVMNLIILVNLIHLFIFRKSNF-IFDKLHKVGIKTRRQ 335

Query: 319 -LGCPINDLNVILLFLRANISELISFSWLSVL 349
                  D+N++ +F   N   + S + L  +
Sbjct: 336 WRRSQFCDINILAMFCNENRDHIKSLNRLDFI 367


>gi|197276594 RNA binding motif protein 20 [Homo sapiens]
          Length = 1227

 Score = 29.6 bits (65), Expect = 4.9
 Identities = 16/46 (34%), Positives = 23/46 (50%), Gaps = 3/46 (6%)

Query: 60  SGSPISCFSPSNFSIRQAAYV---DSSCWDSLLHHKQDGPGQDKMK 102
           SGSP    S S++  R+  Y      + WD  L  +QD PG+ + K
Sbjct: 740 SGSPNLPHSVSSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRK 785


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 29.3 bits (64), Expect = 6.4
 Identities = 19/50 (38%), Positives = 27/50 (54%), Gaps = 5/50 (10%)

Query: 136  LSSD--LLFIISELDKSYNRSIRLVQHMLKIRQKSSDPYVFWNELEKARK 183
            LS D  LL + S+L+ SYN+     + M  ++ +       WNELEK RK
Sbjct: 2811 LSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDH---LWNELEKFRK 2857


>gi|55742693 zyg-11 homolog B [Homo sapiens]
          Length = 744

 Score = 28.9 bits (63), Expect = 8.4
 Identities = 20/66 (30%), Positives = 30/66 (45%), Gaps = 1/66 (1%)

Query: 196 LACKQRSHSLVATYLLRNSLLLIFTSATYLYLGHF-HLDVFFQEEFSCSIKTGLLSDETH 254
           LACK R  SL   +L    +           L H  HLD+   ++F+  I   LL  +  
Sbjct: 205 LACKDRLKSLTMHHLKCLKMTTTQILDVVRELKHLNHLDISDDKQFTSDIALRLLEQKDI 264

Query: 255 VPNLIT 260
           +PNL++
Sbjct: 265 LPNLVS 270


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.138    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,966,566
Number of Sequences: 37866
Number of extensions: 574843
Number of successful extensions: 1803
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1787
Number of HSP's gapped (non-prelim): 7
length of query: 392
length of database: 18,247,518
effective HSP length: 104
effective length of query: 288
effective length of database: 14,309,454
effective search space: 4121122752
effective search space used: 4121122752
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.