Guide to the Human Genome
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Search of human proteins with 148612857

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148612857 sickle tail isoform 3 [Homo sapiens]
         (1309 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148612857 sickle tail isoform 3 [Homo sapiens]                    2605   0.0  
gi|148612813 sickle tail isoform 2 [Homo sapiens]                    2425   0.0  
gi|50843820 sickle tail isoform 1 [Homo sapiens]                     2181   0.0  
gi|115334682 SNAP25-interacting protein [Homo sapiens]                617   e-176
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    73   2e-12
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        67   1e-10
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   64   7e-10
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    64   7e-10
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         62   5e-09
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho...    59   3e-08
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora...    57   9e-08
gi|41281612 zinc finger protein 828 [Homo sapiens]                     57   9e-08
gi|163965366 nascent polypeptide-associated complex alpha subuni...    57   9e-08
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          57   1e-07
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          57   1e-07
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          57   1e-07
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              57   1e-07
gi|18959210 WIRE protein [Homo sapiens]                                57   1e-07
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom...    56   2e-07
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom...    56   2e-07
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap...    56   2e-07
gi|33946327 nucleoporin 214kDa [Homo sapiens]                          56   3e-07
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   56   3e-07
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   56   3e-07
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]        56   3e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    56   3e-07
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]       56   3e-07
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]       56   3e-07
gi|54860079 nadrin isoform 1 [Homo sapiens]                            55   3e-07
gi|54860105 nadrin isoform 2 [Homo sapiens]                            55   4e-07

>gi|148612857 sickle tail isoform 3 [Homo sapiens]
          Length = 1309

 Score = 2605 bits (6752), Expect = 0.0
 Identities = 1309/1309 (100%), Positives = 1309/1309 (100%)

Query: 1    MEENESQKCEPCLPYSADRRQMQEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSS 60
            MEENESQKCEPCLPYSADRRQMQEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSS
Sbjct: 1    MEENESQKCEPCLPYSADRRQMQEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSS 60

Query: 61   RNIPRRHTLGGPRSSKEILGMQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQTR 120
            RNIPRRHTLGGPRSSKEILGMQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQTR
Sbjct: 61   RNIPRRHTLGGPRSSKEILGMQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQTR 120

Query: 121  SPKLSHSPQPPSLGDPVEHLSETSADSLEAMSEGDAPTPFSRGSRTRASLPVVRSTNQTK 180
            SPKLSHSPQPPSLGDPVEHLSETSADSLEAMSEGDAPTPFSRGSRTRASLPVVRSTNQTK
Sbjct: 121  SPKLSHSPQPPSLGDPVEHLSETSADSLEAMSEGDAPTPFSRGSRTRASLPVVRSTNQTK 180

Query: 181  ERSLGVLYLQYGDETKQLRMPNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDES 240
            ERSLGVLYLQYGDETKQLRMPNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDES
Sbjct: 181  ERSLGVLYLQYGDETKQLRMPNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDES 240

Query: 241  RNVYYELNDVRNIQDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRP 300
            RNVYYELNDVRNIQDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRP
Sbjct: 241  RNVYYELNDVRNIQDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRP 300

Query: 301  GSTAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSLPVSRPI 360
            GSTAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSLPVSRPI
Sbjct: 301  GSTAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSLPVSRPI 360

Query: 361  SPSPSAILERRDVKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDH 420
            SPSPSAILERRDVKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDH
Sbjct: 361  SPSPSAILERRDVKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDH 420

Query: 421  IIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVSD 480
            IIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVSD
Sbjct: 421  IIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVSD 480

Query: 481  LRMIDMHAHYNAHGPPHTMQPDRASPSRQAFKKEPGTLVYIEKPRSAAGLSSLVDLGPPL 540
            LRMIDMHAHYNAHGPPHTMQPDRASPSRQAFKKEPGTLVYIEKPRSAAGLSSLVDLGPPL
Sbjct: 481  LRMIDMHAHYNAHGPPHTMQPDRASPSRQAFKKEPGTLVYIEKPRSAAGLSSLVDLGPPL 540

Query: 541  MEKQVFAYSTATIPKDRETSEKMMKTTANRNHTDSAGTPHVSGGKMLSALESTVPPSQPP 600
            MEKQVFAYSTATIPKDRETSEKMMKTTANRNHTDSAGTPHVSGGKMLSALESTVPPSQPP
Sbjct: 541  MEKQVFAYSTATIPKDRETSEKMMKTTANRNHTDSAGTPHVSGGKMLSALESTVPPSQPP 600

Query: 601  PVGTSAIHMSLLEMRRSVAELRLQLQQMRQLQLQNQELLRAMMKKAELEISGKVMETMKR 660
            PVGTSAIHMSLLEMRRSVAELRLQLQQMRQLQLQNQELLRAMMKKAELEISGKVMETMKR
Sbjct: 601  PVGTSAIHMSLLEMRRSVAELRLQLQQMRQLQLQNQELLRAMMKKAELEISGKVMETMKR 660

Query: 661  LEDPVQRQRVLVEQERQKYLHEEEKIVKKLCELEDFVEDLKKDSTAASRLVTLKDVEDGA 720
            LEDPVQRQRVLVEQERQKYLHEEEKIVKKLCELEDFVEDLKKDSTAASRLVTLKDVEDGA
Sbjct: 661  LEDPVQRQRVLVEQERQKYLHEEEKIVKKLCELEDFVEDLKKDSTAASRLVTLKDVEDGA 720

Query: 721  FLLRQVGEAVATLKGEFPTLQNKMRAILRIEVEAVRFLKEEPHKLDSLLKRVRSMTDVLT 780
            FLLRQVGEAVATLKGEFPTLQNKMRAILRIEVEAVRFLKEEPHKLDSLLKRVRSMTDVLT
Sbjct: 721  FLLRQVGEAVATLKGEFPTLQNKMRAILRIEVEAVRFLKEEPHKLDSLLKRVRSMTDVLT 780

Query: 781  MLRRHVTDGLLKGTDAAQAAQYMAMEKATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSE 840
            MLRRHVTDGLLKGTDAAQAAQYMAMEKATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSE
Sbjct: 781  MLRRHVTDGLLKGTDAAQAAQYMAMEKATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSE 840

Query: 841  VVPLSGMMVRHAQSSPVVIQPSQHSVALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQS 900
            VVPLSGMMVRHAQSSPVVIQPSQHSVALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQS
Sbjct: 841  VVPLSGMMVRHAQSSPVVIQPSQHSVALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQS 900

Query: 901  PQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQ 960
            PQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQ
Sbjct: 901  PQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQ 960

Query: 961  ANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRS 1020
            ANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRS
Sbjct: 961  ANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRS 1020

Query: 1021 YLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPV 1080
            YLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPV
Sbjct: 1021 YLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPV 1080

Query: 1081 TTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPR 1140
            TTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPR
Sbjct: 1081 TTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPR 1140

Query: 1141 QYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPS 1200
            QYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPS
Sbjct: 1141 QYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPS 1200

Query: 1201 IASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFS 1260
            IASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFS
Sbjct: 1201 IASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFS 1260

Query: 1261 SSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKETS 1309
            SSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKETS
Sbjct: 1261 SSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKETS 1309


>gi|148612813 sickle tail isoform 2 [Homo sapiens]
          Length = 1264

 Score = 2425 bits (6284), Expect = 0.0
 Identities = 1229/1264 (97%), Positives = 1229/1264 (97%), Gaps = 35/1264 (2%)

Query: 81   MQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQTRSPKLSHSPQPPSLGDPVEHL 140
            MQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQTRSPKLSHSPQPPSLGDPVEHL
Sbjct: 1    MQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQTRSPKLSHSPQPPSLGDPVEHL 60

Query: 141  SETSADSLEAMSEGDAPTPFSRGSRTRASLPVVRSTNQTKERSLGVLYLQYGDETKQLRM 200
            SETSADSLEAMSEGDAPTPFSRGSRTRASLPVVRSTNQTKERSLGVLYLQYGDETKQLRM
Sbjct: 61   SETSADSLEAMSEGDAPTPFSRGSRTRASLPVVRSTNQTKERSLGVLYLQYGDETKQLRM 120

Query: 201  PNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDESRNVYYELNDVRNIQDRSLLK 260
            PNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDESRNVYYELNDVRNIQDRSLLK
Sbjct: 121  PNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDESRNVYYELNDVRNIQDRSLLK 180

Query: 261  VYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRPGSTAHPPHAIPNSPPSTPVP 320
            VYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRPGSTAHPPHAIPNSPPSTPVP
Sbjct: 181  VYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRPGSTAHPPHAIPNSPPSTPVP 240

Query: 321  HSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSLPVSRPISPSPSAILERRDVKPDEDMS 380
            HSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSLPVSRPISPSPSAILERRDVKPDEDMS
Sbjct: 241  HSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSLPVSRPISPSPSAILERRDVKPDEDMS 300

Query: 381  GKNIAMYRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDHIIAYHRTAIRSASAYCNPSM 440
            GKNIAMYRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDHIIAYHRTAIRSASAYCNPSM
Sbjct: 301  GKNIAMYRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDHIIAYHRTAIRSASAYCNPSM 360

Query: 441  QAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVSDLRMIDMHAHYNAHGPPHTMQ 500
            QAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVSDLRMIDMHAHYNAHGPPHTMQ
Sbjct: 361  QAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVSDLRMIDMHAHYNAHGPPHTMQ 420

Query: 501  PDRASPSRQAFKKEPGTLVYIEKPRSAAGLSSLVDLGPPLMEKQVFAYSTATIPKDRET- 559
            PDRASPSRQAFKKEPGTLVYIEKPRSAAGLSSLVDLGPPLMEKQVFAYSTATIPKDRET 
Sbjct: 421  PDRASPSRQAFKKEPGTLVYIEKPRSAAGLSSLVDLGPPLMEKQVFAYSTATIPKDRETR 480

Query: 560  ----------------------------------SEKMMKTTANRNHTDSAGTPHVSGGK 585
                                              SEKMMKTTANRNHTDSAGTPHVSGGK
Sbjct: 481  ERMQAMEKQIASLTGLVQSALFKGPITSYSKDASSEKMMKTTANRNHTDSAGTPHVSGGK 540

Query: 586  MLSALESTVPPSQPPPVGTSAIHMSLLEMRRSVAELRLQLQQMRQLQLQNQELLRAMMKK 645
            MLSALESTVPPSQPPPVGTSAIHMSLLEMRRSVAELRLQLQQMRQLQLQNQELLRAMMKK
Sbjct: 541  MLSALESTVPPSQPPPVGTSAIHMSLLEMRRSVAELRLQLQQMRQLQLQNQELLRAMMKK 600

Query: 646  AELEISGKVMETMKRLEDPVQRQRVLVEQERQKYLHEEEKIVKKLCELEDFVEDLKKDST 705
            AELEISGKVMETMKRLEDPVQRQRVLVEQERQKYLHEEEKIVKKLCELEDFVEDLKKDST
Sbjct: 601  AELEISGKVMETMKRLEDPVQRQRVLVEQERQKYLHEEEKIVKKLCELEDFVEDLKKDST 660

Query: 706  AASRLVTLKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMRAILRIEVEAVRFLKEEPHKL 765
            AASRLVTLKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMRAILRIEVEAVRFLKEEPHKL
Sbjct: 661  AASRLVTLKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMRAILRIEVEAVRFLKEEPHKL 720

Query: 766  DSLLKRVRSMTDVLTMLRRHVTDGLLKGTDAAQAAQYMAMEKATAAEVLKSQEEAAHTSG 825
            DSLLKRVRSMTDVLTMLRRHVTDGLLKGTDAAQAAQYMAMEKATAAEVLKSQEEAAHTSG
Sbjct: 721  DSLLKRVRSMTDVLTMLRRHVTDGLLKGTDAAQAAQYMAMEKATAAEVLKSQEEAAHTSG 780

Query: 826  QPFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHSVALLNPAQNLPHVASSPAVP 885
            QPFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHSVALLNPAQNLPHVASSPAVP
Sbjct: 781  QPFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHSVALLNPAQNLPHVASSPAVP 840

Query: 886  QEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQNLD 945
            QEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQNLD
Sbjct: 841  QEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQNLD 900

Query: 946  HYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKL 1005
            HYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKL
Sbjct: 901  HYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKL 960

Query: 1006 GGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYP 1065
            GGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYP
Sbjct: 961  GGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYP 1020

Query: 1066 AEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPG 1125
            AEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPG
Sbjct: 1021 AEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPG 1080

Query: 1126 TLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSS 1185
            TLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSS
Sbjct: 1081 TLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSS 1140

Query: 1186 GDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFS 1245
            GDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFS
Sbjct: 1141 GDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFS 1200

Query: 1246 PQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTA 1305
            PQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTA
Sbjct: 1201 PQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTA 1260

Query: 1306 KETS 1309
            KETS
Sbjct: 1261 KETS 1264


>gi|50843820 sickle tail isoform 1 [Homo sapiens]
          Length = 1943

 Score = 2181 bits (5651), Expect = 0.0
 Identities = 1109/1170 (94%), Positives = 1114/1170 (95%), Gaps = 38/1170 (3%)

Query: 1    MEENESQKCEPCLPYSADRRQMQEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSS 60
            MEENESQKCEPCLPYSADRRQMQEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSS
Sbjct: 1    MEENESQKCEPCLPYSADRRQMQEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSS 60

Query: 61   RNIPRRHTLGGPRSSKEILGMQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQTR 120
            RNIPRRHTLGGPRSSKEILGMQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQTR
Sbjct: 61   RNIPRRHTLGGPRSSKEILGMQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQTR 120

Query: 121  SPKLSHSPQPPSLGDPVEHLSETSADSLEAMSEGDAPTPFSRGSRTRASLPVVRSTNQTK 180
            SPKLSHSPQPPSLGDPVEHLSETSADSLEAMSEGDAPTPFSRGSRTRASLPVVRSTNQTK
Sbjct: 121  SPKLSHSPQPPSLGDPVEHLSETSADSLEAMSEGDAPTPFSRGSRTRASLPVVRSTNQTK 180

Query: 181  ERSLGVLYLQYGDETKQLRMPNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDES 240
            ERSLGVLYLQYGDETKQLRMPNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDES
Sbjct: 181  ERSLGVLYLQYGDETKQLRMPNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDES 240

Query: 241  RNVYYELNDVRNIQDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRP 300
            RNVYYELNDVRNIQDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRP
Sbjct: 241  RNVYYELNDVRNIQDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRP 300

Query: 301  GSTAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSLPVSRPI 360
            GSTAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSLPVSRPI
Sbjct: 301  GSTAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSLPVSRPI 360

Query: 361  SPSPSAILERRDVKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDH 420
            SPSPSAILERRDVKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDH
Sbjct: 361  SPSPSAILERRDVKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDH 420

Query: 421  IIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVSD 480
            IIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVSD
Sbjct: 421  IIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVSD 480

Query: 481  LRMIDMHAHYNAHGPPHTMQPDRASPSRQAFKKEPGTLVYIEKPRSAAGLSSLVDLGPPL 540
            LRMIDMHAHYNAHGPPHTMQPDRASPSRQAFKKEPGTLVYIEKPRSAAGLSSLVDLGPPL
Sbjct: 481  LRMIDMHAHYNAHGPPHTMQPDRASPSRQAFKKEPGTLVYIEKPRSAAGLSSLVDLGPPL 540

Query: 541  MEKQVFAYSTATIPKDRET-----------------------------------SEKMMK 565
            MEKQVFAYSTATIPKDRET                                   SEKMMK
Sbjct: 541  MEKQVFAYSTATIPKDRETRERMQAMEKQIASLTGLVQSALFKGPITSYSKDASSEKMMK 600

Query: 566  TTANRNHTDSAGTPHVSGGKMLSALESTVPPSQPPPVGTSAIHMSLLEMRRSVAELRLQL 625
            TTANRNHTDSAGTPHVSGGKMLSALESTVPPSQPPPVGTSAIHMSLLEMRRSVAELRLQL
Sbjct: 601  TTANRNHTDSAGTPHVSGGKMLSALESTVPPSQPPPVGTSAIHMSLLEMRRSVAELRLQL 660

Query: 626  QQMRQLQLQNQELLRAMMKKAELEISGKVMETMKRLEDPVQRQRVLVEQERQKYLHEEEK 685
            QQMRQLQLQNQELLRAMMKKAELEISGKVMETMKRLEDPVQRQRVLVEQERQKYLHEEEK
Sbjct: 661  QQMRQLQLQNQELLRAMMKKAELEISGKVMETMKRLEDPVQRQRVLVEQERQKYLHEEEK 720

Query: 686  IVKKLCELEDFVEDLKKDSTAASRLVTLKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMR 745
            IVKKLCELEDFVEDLKKDSTAASRLVTLKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMR
Sbjct: 721  IVKKLCELEDFVEDLKKDSTAASRLVTLKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMR 780

Query: 746  AILRIEVEAVRFLKEEPHKLDSLLKRVRSMTDVLTMLRRHVTDGLLKGTDAAQAAQYMAM 805
            AILRIEVEAVRFLKEEPHKLDSLLKRVRSMTDVLTMLRRHVTDGLLKGTDAAQAAQYMAM
Sbjct: 781  AILRIEVEAVRFLKEEPHKLDSLLKRVRSMTDVLTMLRRHVTDGLLKGTDAAQAAQYMAM 840

Query: 806  EKATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHS 865
            EKATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHS
Sbjct: 841  EKATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHS 900

Query: 866  VALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKN 925
            VALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKN
Sbjct: 901  VALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKN 960

Query: 926  RAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAP 985
            RAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAP
Sbjct: 961  RAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAP 1020

Query: 986  VDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENIT 1045
            VDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENIT
Sbjct: 1021 VDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENIT 1080

Query: 1046 AKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGS 1105
            AKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQ  
Sbjct: 1081 AKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQAF 1140

Query: 1106 SGAPQTSRMPVPMSAKNRPGTLDKPGKQSK 1135
                + S M V  ++   P   D   K ++
Sbjct: 1141 Q---KCSFMDVNSNSHAEPSRADSHVKDTR 1167



 Score =  414 bits (1065), Expect = e-115
 Identities = 220/275 (80%), Positives = 226/275 (82%), Gaps = 19/275 (6%)

Query: 1035 VVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEE 1094
            +V T    N  + ASS         R    P E P +     PP    S+S+        
Sbjct: 1688 LVDTSCSSNRDSVASSSHIAQEASPRPLLVPDEGPTAL---EPPTSIPSASR-------- 1736

Query: 1095 GDKIMAELQGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGG 1154
                    +GSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGG
Sbjct: 1737 --------KGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGG 1788

Query: 1155 DFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPA 1214
            DFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPA
Sbjct: 1789 DFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPA 1848

Query: 1215 HSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQ 1274
            HSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQ
Sbjct: 1849 HSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQ 1908

Query: 1275 GAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKETS 1309
            GAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKETS
Sbjct: 1909 GAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKETS 1943



 Score = 31.2 bits (69), Expect = 6.8
 Identities = 68/325 (20%), Positives = 117/325 (36%), Gaps = 51/325 (15%)

Query: 788  DGLLKGTDAAQAAQYMAME-KATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSEVVPLSG 846
            DG LK    A+  +    + + T    ++ QE+ +  S  P   T      K+    L  
Sbjct: 1611 DGTLKQHKEAKRFEIARSQPEDTPENTVRRQEQPSIESTSPISRTDEI--RKNTYRTLDS 1668

Query: 847  MMVRHAQSSPVVIQPSQHSVALLNPAQNLPHVASSPAVPQEATST--LQMSQAPQS---- 900
            +     Q    + + S  ++   + + N   VASS  + QEA+    L   + P +    
Sbjct: 1669 LEQTIKQLENTISEMSPKALVDTSCSSNRDSVASSSHIAQEASPRPLLVPDEGPTALEPP 1728

Query: 901  ---PQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLE 957
               P     GS+           +SAKNR  +++K  K  + K Q+   Y          
Sbjct: 1729 TSIPSASRKGSSGAPQTSRMPVPMSAKNRPGTLDKPGK--QSKLQDPRQYR--------- 1777

Query: 958  EAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDS--PNSEQDLEKLGGK------- 1008
              QAN        +  P +  LP    P       + S  P+S  D   L          
Sbjct: 1778 --QANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSI 1835

Query: 1009 -----SPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATK 1063
                 SP   PP    S +P     + +   + +TG+  +++          SPQ++  +
Sbjct: 1836 ASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSF---------SPQSQNGR 1886

Query: 1064 YPAEEPASAWTPSPPPVTTSSSKDE 1088
             P   P  +++ SPP   +S S ++
Sbjct: 1887 AP---PPLSFSSSPPSPASSVSLNQ 1908



 Score = 30.8 bits (68), Expect = 8.9
 Identities = 65/292 (22%), Positives = 108/292 (36%), Gaps = 51/292 (17%)

Query: 1046 AKASSEDAGPSPQTRATKYPAEE-PASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQG 1104
            A++S     PS  + A   PA+  P  A +P+ P   TS+ +  +  +         + G
Sbjct: 887  AQSSPVVIQPSQHSVALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQSP----QIPMNG 942

Query: 1105 SSGAPQTSRMPVPMSAKNRPGTLDKPGK--QSKLQDPRQYR-----------QANGSAKK 1151
            S+           +SAKNR  +++K  K  + K Q+   Y            QAN     
Sbjct: 943  SAMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSI 1002

Query: 1152 SGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTG 1211
               +  P +  LP    P       + S  P+S  D   L               SP   
Sbjct: 1003 PNLEMPPATGPLPRGDAPVDKVELSEDS--PNSEQDLEKLGGK------------SPPPP 1048

Query: 1212 PPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSF---------SPQSQNGRAP---PPLSF 1259
            PP    S +P     + +   + +TG+  +++          SPQ++  + P   P  ++
Sbjct: 1049 PPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAW 1108

Query: 1260 SSSPPSPASSVSLN------QGAKGTRTIHTPSLTSYKAQNGSSSKATPSTA 1305
            + SPP   +S S +      +G K    +      S+   N S+S A PS A
Sbjct: 1109 TPSPPPVTTSSSKDEEEEEEEGDKIMAELQAFQKCSFMDVN-SNSHAEPSRA 1159


>gi|115334682 SNAP25-interacting protein [Homo sapiens]
          Length = 1183

 Score =  617 bits (1591), Expect = e-176
 Identities = 453/1261 (35%), Positives = 657/1261 (52%), Gaps = 188/1261 (14%)

Query: 23   QEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSSRNI------PRRHTLGGPRSSK 76
            Q+  + +  + S +DAE  R    L  G   GS  +   N+       RRHT+   +S +
Sbjct: 7    QDPERSSPPMLSADDAEYPREYRTLGGGGGGGSGGRRFSNVGLVHTSERRHTVIAAQSLE 66

Query: 77   EILGMQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQ-------TRSPKLSHSPQ 129
             + G+Q ++ DRKR+AF++HLK KYP HA A+ G Q+R+R+Q       TRS + +   Q
Sbjct: 67   ALSGLQKADADRKRDAFMDHLKSKYPQHALALRGQQDRMREQPNYWSFKTRSSRHTQGAQ 126

Query: 130  PPSLGDPVEHLSETSADSLEAMSEGDAPTPFSRGSRTRASLPVVRSTNQTKERSLGVLYL 189
            P  L D    LS  SA+SLE MSE + P  FSR +R R SLP+ RS +QTK RS GVL+L
Sbjct: 127  P-GLADQAAKLSYASAESLETMSEAELPLGFSRMNRFRQSLPLSRSASQTKLRSPGVLFL 185

Query: 190  QYGDETKQLRMPNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDESRNVYYELND 249
            Q+G+ET+++ + +E++S DT+ AL    FPQ+LTM ML+SP+ AI IKDE+RNV+YEL D
Sbjct: 186  QFGEETRRVHITHEVSSLDTLHALIAHMFPQKLTMGMLKSPNTAILIKDEARNVFYELED 245

Query: 250  VRNIQDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRPGSTAHPPHA 309
            VR+IQDRS++K+Y K+P +A        NGD+R  RE+VYA  +     R  + +  PH 
Sbjct: 246  VRDIQDRSIIKIYRKEPLYAAFPGSHLTNGDLR--REMVYASRESSPTRRLNNLSPAPHL 303

Query: 310  IPNSPPSTPVPHSMP-------PSPSRIPYGGTRSMVVPGNATI-PRDRISSLPVSRPIS 361
               SPP   +P  +P       PS SR+ Y G R     G+      +R+   P ++ +S
Sbjct: 304  ASGSPPPG-LPSGLPSGLQSGSPSRSRLSYAGGRPPSYAGSPVHHAAERLGGAPAAQGVS 362

Query: 362  PSPSAILERRDVKPDEDMSGK--NIAMYRNEGFYADPY-LYHEGRMSIASSHGGHPLDVP 418
            PSPSAILERRDVKPDED++ K   + + + EG YADPY L HEGR+S+A++  G P   P
Sbjct: 363  PSPSAILERRDVKPDEDLASKAGGMVLVKGEGLYADPYGLLHEGRLSLAAA-AGDPFAYP 421

Query: 419  DHIIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRV 478
                 Y R ++RS S Y   ++Q+++  E SLY+      P  +    G + PP+SP ++
Sbjct: 422  GAGGLYKRGSVRSLSTYSAAALQSDL--EDSLYKAAGGGGP-LYGDGYGFRLPPSSPQKL 478

Query: 479  SDLRMIDMHAHYNAHGPPHTMQ---PDRASPSRQAFKKEPGTL-VYIEKP----RSAAGL 530
            +D+      A      PPH+     P R SP RQ+F+K+ G+  V+ E P    RSA   
Sbjct: 479  ADVA-----APPGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSSSVFAESPGGKTRSAGSA 533

Query: 531  S----------------SLVDLGPPL-------------MEKQVFAYSTATIPKDRETSE 561
            S                SLV  GPP+             MEKQ+ A  T  +        
Sbjct: 534  STAGAPPSELFPGPGERSLVGFGPPVPAKDTETRERMEAMEKQI-ASLTGLVQSALLRGS 592

Query: 562  KMMKTTANRNHTDSAGTPHV---SGGKMLSALE---------STVPPSQPPPVGTSAIHM 609
            +    +     ++ A TP     SGG+   A           S+ P  QP  V    + +
Sbjct: 593  EPETPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPPSASSTPAGQPTAVSRLQMQL 652

Query: 610  SLLEMRRSVAELRLQLQQMRQLQLQNQELLRAMMKKAELEISGKVMETMKRLEDPVQRQR 669
             L  ++ S ++LR QLQQ+R+LQLQNQE +RA++K+ E E+S +V E  +R EDP+QRQR
Sbjct: 653  HLRGLQNSASDLRGQLQQLRKLQLQNQESVRALLKRTEAELSMRVSEAARRQEDPLQRQR 712

Query: 670  VLVEQERQKYLHEEEKIVKKLCELEDFVEDLKKDSTAASRLVTLKDVEDGAFLLRQVGEA 729
             LVE+ER +YL++EE I ++L +LE  VE +++D +   RLV   ++E+ A +L+Q+GE 
Sbjct: 713  TLVEEERLRYLNDEELITQQLNDLEKSVEKIQRDVSHNHRLVPGPELEEKALVLKQLGET 772

Query: 730  VATLKGEFPTLQNKMRAILRIEVEAVRFLKEEPHKLDSLLKRVRSMTDVLTMLRRHVTDG 789
            +  LK  FP LQ+KMR +LR+EVEAV+FLKEEP +LD LLKR R            VTD 
Sbjct: 773  LTELKAHFPGLQSKMRVVLRVEVEAVKFLKEEPQRLDGLLKRCRG-----------VTDT 821

Query: 790  LLKGTDAAQAAQYMAMEKATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSEVVPLSGMMV 849
            L      AQ  + +          L SQ     T+   F+ +        E+ P S    
Sbjct: 822  L------AQIRRQVDEGVWPPPNNLLSQSPKKVTAETDFNKS-----VDFEMPPPS---- 866

Query: 850  RHAQSSPVVIQPSQHSVALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSA 909
                                 P  NL H  S PA     T              P  G+ 
Sbjct: 867  ---------------------PPLNL-HELSGPAEGASLT--------------PKGGNP 890

Query: 910  MQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPN 969
             + L      SV   ++AVS+E AE+ WEEKR  L  Y+ K+  +LLEE QA ++K+IP+
Sbjct: 891  TKGLDTPGKRSV---DKAVSVEAAERDWEEKRAALTQYSAKDINRLLEETQAELLKAIPD 947

Query: 970  LEMPPAT--GPLPRGD-----APVDKVELSEDSPNSEQDLEKL-------GGKSPPPPPP 1015
            L+       GP P  D     AP  +       P+  +  ++L          S  PPPP
Sbjct: 948  LDCASKAHPGPAPTPDHKPPKAPHGQKAAPRTEPSGRRGSDELTVPRYRTEKPSKSPPPP 1007

Query: 1016 PPRRSYLPGSGLTTTRSGDVVYTGRKEN-ITAKASSEDAG-PSPQTRATKYPAEEPASAW 1073
            PPRRS+    GLTTTR+G+VV T +K++    KA SE+     PQ +  +  +E    A 
Sbjct: 1008 PPRRSFPSSHGLTTTRTGEVVVTSKKDSAFIKKAESEELEVQKPQVKLRRAVSEVARPA- 1066

Query: 1074 TPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVP-----MSAKNRPGTLD 1128
              S PP+  S+ KDE++E    D+I+AEL+   G+    ++  P      +A+ + G+ D
Sbjct: 1067 --STPPIMASAIKDEDDE----DRIIAELESGGGSVPPMKVVTPGASRLKAAQGQAGSPD 1120

Query: 1129 KP--GKQ-SKLQDPRQYRQANGSAKKSGGDFKPTS-----PSLPASKIPALSPSSGKSSS 1180
            K   GKQ ++    +  +QA   +K+  G  + +S     PS   + IP L+    ++SS
Sbjct: 1121 KSKHGKQRAEYMRIQAQQQATKPSKEMSGSNETSSPVSEKPSASRTSIPVLTSFGARNSS 1180

Query: 1181 L 1181
            +
Sbjct: 1181 I 1181


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
            sapiens]
          Length = 699

 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 108/537 (20%), Positives = 184/537 (34%), Gaps = 45/537 (8%)

Query: 804  AMEKATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQ 863
            A +KA++++   S EE     G P      P          +      + SS        
Sbjct: 78   AKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDD 137

Query: 864  HSVALLNPAQN--LPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSV 921
                   P Q    P   ++ A P++A S+   S +    + P N     +    +  + 
Sbjct: 138  EEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTK 197

Query: 922  SAKNRAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPR 981
            +    A +  K          +    +    +   E+A A   K++P  ++  A  P+  
Sbjct: 198  APPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVV-AKAPVKA 256

Query: 982  GDAPVDKVELSEDSPNSEQDLEKLGGKS--------PPPPPPPPRRSYLPGSGLTTTRSG 1033
               P  K   SEDS + E++ +K   K+        PPP  PPP++S      L T    
Sbjct: 257  ATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKS------LGTQPPK 310

Query: 1034 DVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPV-------TTSSSK 1086
              V   +++ + +   S D   S      K P +   S  T  PPP        + SS  
Sbjct: 311  KAV--EKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDS 368

Query: 1087 DEEEEEEEGDKIMAELQGSSGAPQ-TSRMPV--PMSAKNRPGTLDKPGKQSKLQDPRQYR 1143
            D  E++E   K     + SS  P  T++ P   P +A  +P    +     K        
Sbjct: 369  DSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEE 428

Query: 1144 QANGS----AKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKP 1199
            +++ S     KK     KP + +  A  +PA     G   S   S   SS       +K 
Sbjct: 429  ESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKS 488

Query: 1200 SI---------ASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQN 1250
            ++          + P  P +     + S   S S+ S + +     GKG   S  PQ+  
Sbjct: 489  AVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKG---SPRPQAPK 545

Query: 1251 GRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKE 1307
                  L+  +   +  S     +  K    +        + QN ++ +A    AK+
Sbjct: 546  ANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKK 602



 Score = 54.3 bits (129), Expect = 8e-07
 Identities = 72/336 (21%), Positives = 123/336 (36%), Gaps = 23/336 (6%)

Query: 975  ATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRSYLP---GSGLTTTR 1031
            A GP+ +      K   S DS +S ++ E++ G        P +R  LP    +   +  
Sbjct: 70   ANGPVAK---KAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASES 126

Query: 1032 SGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEE 1091
            S     +   +    K      G  PQ +A K P ++  S+ + S      SSS+DE  +
Sbjct: 127  SSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSD-----SSSEDEPPK 181

Query: 1092 EEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKK 1151
             ++       ++  + AP       P  A  +  +       S   D  +  +A  + KK
Sbjct: 182  NQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKK 241

Query: 1152 SGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTG 1211
            +    K      P     A +P+   SSS  SSS +      P   KP   S+   P   
Sbjct: 242  TVPK-KQVVAKAPVKA--ATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAP 298

Query: 1212 PPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPP---LSFSSSPPSP-- 1266
            PP  S    P     +++ Q    + +         S+  + PP    +S +++ P P  
Sbjct: 299  PPKKSLGTQP--PKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAK 356

Query: 1267 --ASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKA 1300
              A S S +  +  +     PS  +   +N S+  A
Sbjct: 357  KAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPA 392


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 106/469 (22%), Positives = 168/469 (35%), Gaps = 70/469 (14%)

Query: 824  SGQPFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHSVALLNPAQNLPHVASSPA 883
            SG P  +   P  +++   P S  +V            S H+ A +N A +    A +PA
Sbjct: 2314 SGTPPTAANYPSSSRTPQAPASANLVGPR---------SAHATAPVNIAGSRTAAALAPA 2364

Query: 884  VPQEATSTLQMSQAP-QSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQ 942
                A     +S A   SP++P++              VS +     +++A  +      
Sbjct: 2365 SLTSARMAPALSGANLTSPRVPLSA----------YERVSGRTSPPLLDRARSRTPPSAP 2414

Query: 943  NLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDL 1002
            +      +        + ++ M   P+  + P     PR   P         S  S+Q  
Sbjct: 2415 SQSRMTSER-----APSPSSRMGQAPSQSLLPPAQDQPRSPVP---------SAFSDQSR 2460

Query: 1003 EKLGGKSPPPPPPPPRRSYLPGSGLTTTRS-GD------VVYTGRKENITAKASSEDAGP 1055
              +   +P        +S   G+  TTT S GD      V   G   +   +  +     
Sbjct: 2461 CLIAQTTPVAGS----QSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQ 2516

Query: 1056 SPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTS--- 1112
             P   A   PA+E  S+ + S    ++SSS              ++ +GSS   Q     
Sbjct: 2517 QPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVAL 2576

Query: 1113 -RMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPAL 1171
             R+P P  A   P    + G+  +    ++ R+++ S+  S      +S S  +S     
Sbjct: 2577 KRVPSPTPA---PKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSS----- 2628

Query: 1172 SPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQ 1231
            S SS  SSS  SSS  SS+ P+P    P     P SP+  PP    S  P     SL+  
Sbjct: 2629 SSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLR-- 2686

Query: 1232 SLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTR 1280
                      LS+SP  +   +P P     SP    SS S     +G R
Sbjct: 2687 ------DSRSLSYSPVERRRPSPQP-----SPRDQQSSSSERGSRRGQR 2724



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 76/331 (22%), Positives = 119/331 (35%), Gaps = 53/331 (16%)

Query: 1013 PPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSED---AGPSPQTRATKY----- 1064
            P P  RR++   S  + + S     T R  + +A A +     AG SP   + +      
Sbjct: 253  PAPKSRRAHRSTSADSASSSD----TSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDA 308

Query: 1065 PAEEPASAWT--PSPPPVTTSS------SKDEEEEEEEGDKIMAELQGSSGAPQTSRMPV 1116
            P  EP +  T  PS P   T         KD++++E+   +     + SS  P+    P 
Sbjct: 309  PFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPA-PT 367

Query: 1117 PMSAKNRPGT-------------LDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPS- 1162
            P+ A+   G+             ++ P + S  +D    +      + S  +  P SP  
Sbjct: 368  PLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQP 427

Query: 1163 LPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPS 1222
               S+  + SP S K +  P S  + S+ P         A    S    P          
Sbjct: 428  TKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSP 487

Query: 1223 VSNGSLKFQSLTHTGKGHHLSFSPQSQ---------NGRAPPPLSFSSSPPSPASSVSLN 1273
             +    + +S T T +GH  S SPQ +           R+P     S SP  P  S S N
Sbjct: 488  ATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRN 547

Query: 1274 QGAKGTRTIHTPSLTSYKAQNGSSSKATPST 1304
               +G          S  A+ G S   +P+T
Sbjct: 548  TQRRG---------RSRSARRGRSHSRSPAT 569



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 64/269 (23%), Positives = 99/269 (36%), Gaps = 19/269 (7%)

Query: 1055 PSPQTRATKYPAEEPASAWTPSPPPVTTSSS--KDEEEEEEEGDKIMAELQGSSGAPQT- 1111
            PS ++R+   P     S  TPS   ++ SS   KD       G             PQT 
Sbjct: 1435 PSRRSRSGSSPGLRDGSG-TPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTP 1493

Query: 1112 ---SRMPVPMSAKNRPGT--LDKPGKQSKLQDPRQYRQANGSAKKSGG----DFKPTSPS 1162
               SR P      N+  T   ++ G +S +      R   G   +SG     D KP++  
Sbjct: 1494 RPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASP 1553

Query: 1163 LPASKIPALSPSSGKSSSLP----SSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSAS 1218
               S+  + SP S   +  P    S SG S  + +     P  + +  SP+      +A 
Sbjct: 1554 QERSESDS-SPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAP 1612

Query: 1219 LIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKG 1278
               S S+ S + ++          S S  S  GR P P   SS+  SP          +G
Sbjct: 1613 RAQSGSDSSPEPKAPAPRALPRR-SRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRG 1671

Query: 1279 TRTIHTPSLTSYKAQNGSSSKATPSTAKE 1307
            +R+   P   S       SS+++P   ++
Sbjct: 1672 SRSSPEPKTKSRTPPRRRSSRSSPELTRK 1700



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 87/347 (25%), Positives = 131/347 (37%), Gaps = 57/347 (16%)

Query: 1008 KSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRAT----K 1063
            K P P PP P       S   ++RS       +K+       SE + P  + + +    K
Sbjct: 161  KQPAPEPPKPYSLVRESS---SSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKK 217

Query: 1064 YPAE-EPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQ--------GSSGAPQTSRM 1114
            + +E E       SP P +   SKD++ +         + +         S+ +  TSR 
Sbjct: 218  HRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRS 277

Query: 1115 PVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSG-GDFKPTSPSLP--ASKIPAL 1171
                SA  +  T    G+      P   R+  G A  S  G      PS P  A+K P+ 
Sbjct: 278  R-SRSAAAKTHTTALAGRSPS---PASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPS- 332

Query: 1172 SP-------SSGKSSSLPSSSGD-SSNLPNPPATKP-----------SIASNPLSPQTGP 1212
            SP          KS++ PS S + SS  P PPA  P            +A+ PLS +   
Sbjct: 333  SPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVN 392

Query: 1213 PAHSAS------------LIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFS 1260
            P   AS             +P  S+      S   T    H S SP+S    AP P S  
Sbjct: 393  PPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPK-PAPAPGSHR 451

Query: 1261 SSPPSPASSVSLNQGAKGTRT-IHTPSLTSYKAQNGSSSKATPSTAK 1306
                SP S    +  AK  ++  HTPS    ++++ +++K   S ++
Sbjct: 452  EISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSR 498



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 74/352 (21%), Positives = 121/352 (34%), Gaps = 40/352 (11%)

Query: 995  SPNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGD-VVYTGRKENITAKASSEDA 1053
            +P +   L   G  +PP     P  S  P +  +    G    +     NI    ++   
Sbjct: 2302 TPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAAL 2361

Query: 1054 GPSPQTRATKYPAEEPASAWTP--------------SPP----------PVTTSSSKDEE 1089
             P+  T A   PA   A+  +P              SPP          P   S S+   
Sbjct: 2362 APASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTS 2421

Query: 1090 EEEEEGDKIMAELQGSSGAPQTS---RMPVPMSAKNRPGTL---DKPGKQSKLQDPRQYR 1143
            E        M +    S  P      R PVP +  ++   L     P   S+        
Sbjct: 2422 ERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVA 2481

Query: 1144 QANGSAKKSGGDFKPTSPSLPASKI--PALSPSSGKSSSLPSSSGDSSNLPNPPATKPSI 1201
                SA    G     +P +P S +  P  S  + + S+L +         +  ++  S 
Sbjct: 2482 TTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSS 2541

Query: 1202 ASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQS--QNGRAPPPLSF 1259
            +S+  S  +   + S S        SL  Q      +    + +P+   + GR P P   
Sbjct: 2542 SSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPA 2601

Query: 1260 -----SSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTAK 1306
                 SSS  S +SS S +  +  + +  + S +S  + + SSS ++PS AK
Sbjct: 2602 KRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAK 2653



 Score = 38.9 bits (89), Expect = 0.033
 Identities = 60/263 (22%), Positives = 90/263 (34%), Gaps = 20/263 (7%)

Query: 1015 PPPRRSYLPGSGLTTTRSGDVVYTGRKENIT-AKASSEDAGPSPQTRATKYPAEEPASAW 1073
            P  RRS         +RS      GR  + T A+  S    P  +   ++ PA     + 
Sbjct: 589  PARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSR 648

Query: 1074 TPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQT-----SRMPVPMSAKNRPGTLD 1128
            + +P     S S+          +  A   G S +        SR   P   ++R  +L 
Sbjct: 649  SRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLV 708

Query: 1129 KPGKQSKLQDPRQYRQANGSAKKSGG---DFKPTSPSLPASKIPALSPSSGKSSSLPSSS 1185
            + G+       R+ R  + S +K+       +  S S P  K   +S    +S S P S 
Sbjct: 709  RRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSK 768

Query: 1186 GDSSNLPNPPATKPSIASNPLSPQTG--PPAHSASLIPSVSNGSLKFQSLTHTGKGHHLS 1243
              S         +    S+P   Q    PP  S S      +   K +S T   +    S
Sbjct: 769  AKS----RLSLRRSLSGSSPCPKQKSQTPPRRSRS-----GSSQPKAKSRTPPRRSRSSS 819

Query: 1244 FSPQSQNGRAPPPLSFSSSPPSP 1266
              P  Q  + P   S SSS P P
Sbjct: 820  SPPPKQKSKTPSRQSHSSSSPHP 842



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 103/490 (21%), Positives = 168/490 (34%), Gaps = 68/490 (13%)

Query: 20   RQMQEQGKGNLHVTSPEDAECRRTKERLSNGNSRGSVSKSSRNIPRRHTLGGPRS-SKEI 78
            R  Q +G+     +S E     RT +R S  NS   + KS  +  R  +L  PRS +K  
Sbjct: 716  RTPQRRGRSG---SSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSR 772

Query: 79   LGMQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQT--RSPKLSHSPQPPSLGDP 136
            L ++ S       +     K + P   S     Q + + +T  R  + S SP P      
Sbjct: 773  LSLRRS---LSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKT 829

Query: 137  VEHLSETSADSLEAMSEGDAP---------------TPFSRGSRTRASLPVVRSTNQTKE 181
                S +S+     +  G  P               TP  R     +  P ++S   ++ 
Sbjct: 830  PSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRH 889

Query: 182  RSLGVLYLQYGDETKQLRMPNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDESR 241
               G    +    T   + P+  +S        +S  P+Q +     SPS +      + 
Sbjct: 890  SCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIIS--PRQRSHSGSSSPSPSRVTSRTTP 947

Query: 242  NVYYELNDVRNIQDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRPG 301
                 ++   N++ R L +      +H+ + +P     D +++ E        P     G
Sbjct: 948  RRSRSVSPCSNVESRLLPRY-----SHSGSSSP-----DTKVKPETP------PRQSHSG 991

Query: 302  STAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMV--VPGNATIPRDRISSLPVSRP 359
            S +  P     +PP   +  S  P P         S+V   PG+ ++     SS P    
Sbjct: 992  SISPYPKVKAQTPPGPSLSGSKSPCPQE---KSKDSLVQSCPGSLSLCAGVKSSTPPGES 1048

Query: 360  ISPSPSAILE-RRDVKPDE--DMSGKNIAMYRNEGFYADPYLYHEGRMSIASSHGGHPLD 416
                 S  L+ +    PD   D S   +    +E     P L  + +    S  GG    
Sbjct: 1049 YFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSES----PSLQSKSQ---TSPKGGRSRS 1101

Query: 417  VPDHIIAYHRTAIRS--ASAYCNPSMQAEMHMEQSLYRQKSRKYP---------DSHLPT 465
                     R+ IR        +P +++ M  EQS ++  S  YP          S L T
Sbjct: 1102 SSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLET 1161

Query: 466  LGSKTPPASP 475
              SK   A P
Sbjct: 1162 AESKEKMALP 1171



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 50/251 (19%), Positives = 85/251 (33%), Gaps = 35/251 (13%)

Query: 977  GPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPP-----PPPRRSYLPGSGLTT-- 1029
            GP P G +     E S + P   +   + G +S P P      PP RRS      LT   
Sbjct: 1646 GPSPEGSS---STESSPEHPPKSRTARR-GSRSSPEPKTKSRTPPRRRSSRSSPELTRKA 1701

Query: 1030 --------------TRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTP 1075
                          TRS       R  ++++   +E +  S + R+   P  +  S    
Sbjct: 1702 RLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGR 1761

Query: 1076 SPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSK 1135
            SP P      +       E  +       S  +  TSR      +++R     + G    
Sbjct: 1762 SPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYH 1821

Query: 1136 LQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPP 1195
             + P +   +  S+++  G           S+ P  S    +S + P+    S +  +P 
Sbjct: 1822 SRSPARQESSRTSSRRRRG----------RSRTPPTSRKRSRSRTSPAPWKRSRSRASPA 1871

Query: 1196 ATKPSIASNPL 1206
              + S +  PL
Sbjct: 1872 THRRSRSRTPL 1882



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 72/310 (23%), Positives = 110/310 (35%), Gaps = 38/310 (12%)

Query: 973  PPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRS 1032
            PP   P  R  +P  KV+ +  SP          G S P P     R+       T  RS
Sbjct: 904  PPRQSP-SRSSSPQPKVK-AIISPRQRSH----SGSSSPSPSRVTSRT-------TPRRS 950

Query: 1033 GDVVYTGRKENITAKASSEDAGPSPQTRATKY--PAEEPASAWTP-------SPPPVTTS 1083
              V      E+      S     SP T+      P +  + + +P       +PP  + S
Sbjct: 951  RSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLS 1010

Query: 1084 SSKDEEEEEEEGDKIMAELQGSSG--APQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQ 1141
             SK    +E+  D ++    GS    A   S  P P  +     +L   G+     D R 
Sbjct: 1011 GSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTP-PGESYFGVSSLQLKGQSQTSPDHRS 1069

Query: 1142 YRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLP-----NPPA 1196
               ++   ++S  +    SPSL +      SP  G+S S    +  +S  P        +
Sbjct: 1070 -DTSSPEVRQSHSE----SPSLQSKS--QTSPKGGRSRSSSPVTELASRSPIRQDRGEFS 1122

Query: 1197 TKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPP 1256
              P + S  +SP+       +S  P+V + SL  QS   T +       P  ++  A PP
Sbjct: 1123 ASPMLKSG-MSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPP 1181

Query: 1257 LSFSSSPPSP 1266
                   P P
Sbjct: 1182 RQKDKFSPFP 1191



 Score = 33.9 bits (76), Expect = 1.1
 Identities = 69/310 (22%), Positives = 109/310 (35%), Gaps = 31/310 (10%)

Query: 1006 GGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYT----GRKENITAKASSE-------DAG 1054
            G +S    PP  RR    GS    +RS     T    G +    A  SS           
Sbjct: 2064 GKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMS 2123

Query: 1055 PSPQTRATKYPAEEP-ASAWTP-------------SPPPVTTSSSKDEEEEEEEGDKIMA 1100
            P+P  R       EP  S+ TP              P P      +    E     +I  
Sbjct: 2124 PTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIAL 2183

Query: 1101 ELQGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTS 1160
             L   S    T+R P  MSA      + +      L   R    AN +++         +
Sbjct: 2184 ALTAISLG--TARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAAS--AAA 2239

Query: 1161 PSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLI 1220
             +L +++ PA+  +   + S   ++  + NL +P       A N   P+T P A + +L 
Sbjct: 2240 MNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRT-PTAPAVNLA 2298

Query: 1221 PSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLN-QGAKGT 1279
             + +  +L   SLT +G     +  P S      P  +    P S  ++  +N  G++  
Sbjct: 2299 GARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTA 2358

Query: 1280 RTIHTPSLTS 1289
              +   SLTS
Sbjct: 2359 AALAPASLTS 2368



 Score = 33.1 bits (74), Expect = 1.8
 Identities = 72/324 (22%), Positives = 105/324 (32%), Gaps = 32/324 (9%)

Query: 293  DGPGAPRPGSTAHPPHAIPNSPPSTPVPHSMPPS----------PSRIPYGGTRSMVVPG 342
            D P  P  G +       P + P TP P S  PS          P R   G   S+    
Sbjct: 1468 DIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKT 1527

Query: 343  NATIPRDRISSLPVSRPISPSPSAILERR---DVKPDEDMSGKNIAMYRNEGFYADPYLY 399
             A  P  + S    S+ +   PSA  + R   D  PD     +     R+    + P + 
Sbjct: 1528 VARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRS-GSSPEVD 1586

Query: 400  HEGRMSIASSHGGHPLDVPDHIIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYP 459
             + R+S   S  G   +V D   A  R    S S+   P   A   + +   R +S    
Sbjct: 1587 SKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSS-PEPKAPAPRALPR---RSRSGSSS 1642

Query: 460  DSHLPT-LGSKTPPASPHRVSDLRMIDMHAHYNAHGPPHTMQPDRASPSRQAFKKEP--- 515
                P+  GS +  +SP      R     A   +   P      R  P R++ +  P   
Sbjct: 1643 KGRGPSPEGSSSTESSPEHPPKSRT----ARRGSRSSPEPKTKSRTPPRRRSSRSSPELT 1698

Query: 516  GTLVYIEKPRSAAGLSSLVDLGPPLMEKQVFAYSTATIPKDRET------SEKMMKTTAN 569
                   + RSA+         PP   +     S     K R +      S    KTT+ 
Sbjct: 1699 RKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSR 1758

Query: 570  RNHTDSAGTPHVSGGKMLSALEST 593
            R  + S     +   +  S  E T
Sbjct: 1759 RGRSPSPKPRGLQRSRSRSRREKT 1782


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 64.3 bits (155), Expect = 7e-10
 Identities = 104/477 (21%), Positives = 162/477 (33%), Gaps = 61/477 (12%)

Query: 885  PQEATSTLQMS--QAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQ 942
            P  A+ T++ +  ++P+ P        ++S  I E HSVS    + S   +       R+
Sbjct: 81   PSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRK 140

Query: 943  NLDHYNG---KEFEKLLE--EAQANIMKSIPNLEMP---PATGPLPRGDAPVDKVELSED 994
                 N    +E +K L+  + + N  K  P  + P    A   L  GD  V   + S  
Sbjct: 141  IKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTT 200

Query: 995  SPNSEQDLEKLGGKSP--PPPPPPPRRSYLPGSGLT-----------TTRSGDVVYTGRK 1041
              N      K+    P  P P  PP       + LT           TT +     T  K
Sbjct: 201  QHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGK 260

Query: 1042 ENITA--------KASSEDAGPSPQTRA---------TKYPA------------EEPASA 1072
            E  T+        K S++D  P+ +  A         TK PA            +EPAS 
Sbjct: 261  EKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAST 320

Query: 1073 WTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKN-RPGTLDKPG 1131
                P P T  S+    +E        A       AP T++ P P + K   P T  +P 
Sbjct: 321  TPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA 380

Query: 1132 KQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNL 1191
              +    P   ++   +  K      PT+P  PA   P     +      P++   +   
Sbjct: 381  PTTTKSAPTTPKEPAPTTPKKPA---PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT 437

Query: 1192 PNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNG 1251
            P  PA        P +P+   P       P+ +    K  S T   +    +        
Sbjct: 438  PKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT----KEPSPTTPKEPAPTTTKSAPTTT 493

Query: 1252 RAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSK-ATPSTAKE 1307
            + P P +  S+P +P              T   P+ T+ K    ++ K   P+T KE
Sbjct: 494  KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 550



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 80/369 (21%), Positives = 122/369 (33%), Gaps = 43/369 (11%)

Query: 957  EEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPP---- 1012
            +E     +KS P     PA  P     AP       E +P + ++      K P P    
Sbjct: 323  KEPTPTTIKSAPTTPKEPA--PTTTKSAPTTP---KEPAPTTTKEPAPTTPKEPAPTTTK 377

Query: 1013 -PPPPPRRSY--LPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPA--- 1066
             P P   +S    P     TT       T ++   T         P      TK PA   
Sbjct: 378  EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT 437

Query: 1067 -EEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPG 1125
             +EPA      P P T         +E       A       +P T + P P + K+ P 
Sbjct: 438  PKEPAPTAPKKPAPTTPKEPAPTTPKEP------APTTTKEPSPTTPKEPAPTTTKSAPT 491

Query: 1126 TLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSS 1185
            T  +P   +    P   ++ + +  K      PT+P  PA   P     +      P++ 
Sbjct: 492  TTKEPAPTTTKSAPTTPKEPSPTTTKEPA---PTTPKEPAPTTPKKPAPTTPKEPAPTTP 548

Query: 1186 GDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFS 1245
             +    P P  TK    + P  P    P  +A   P         + LT T        +
Sbjct: 549  KE----PAPTTTKKPAPTTPKEPAPTTPKETAPTTP---------KKLTPTTPEKLAPTT 595

Query: 1246 PQSQNGRAPPPLSFSS----SPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSK-A 1300
            P+      P  L+ ++    +P +P         A    T   P+ T+ K    ++ K  
Sbjct: 596  PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 655

Query: 1301 TPSTAKETS 1309
             P+T KET+
Sbjct: 656  APTTPKETA 664



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 80/364 (21%), Positives = 119/364 (32%), Gaps = 39/364 (10%)

Query: 957  EEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPPPP 1016
            E A     K  P     PA    P+  AP    +L+  +P      EKL   +P  P P 
Sbjct: 550  EPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTP------EKLAPTTPEKPAPT 602

Query: 1017 PRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPA----EEPA-- 1070
                  P    TT               T KA++ +    P     K PA    +EPA  
Sbjct: 603  TPEELAP----TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 658

Query: 1071 -----SAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPG 1125
                 +  TP     TT         ++   K +A          T   P P + K    
Sbjct: 659  TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 718

Query: 1126 TLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSS 1185
            T  K    +  ++P       G+A  +  +  PT+P  PA K   L+P++ K  +  S++
Sbjct: 719  TTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPKKPAPK--ELAPTTTKGPT--STT 773

Query: 1186 GDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFS 1245
             D      P  T P+    P       PA +    P  +   +   + T      H S  
Sbjct: 774  SDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD 833

Query: 1246 PQSQNGRA-PPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPST 1304
              +    A P P +  +SP  P           G  T  TP+ T  +    +  K T   
Sbjct: 834  ESTPELSAEPTPKALENSPKEP-----------GVPTTKTPAATKPEMTTTAKDKTTERD 882

Query: 1305 AKET 1308
             + T
Sbjct: 883  LRTT 886



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 69/306 (22%), Positives = 100/306 (32%), Gaps = 20/306 (6%)

Query: 871  PAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSI 930
            PA   P  A++P  P+E   T     AP +P+ P   +       +E    + K  A + 
Sbjct: 623  PAPTTPK-AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP------KETAPTTPKGTAPTT 675

Query: 931  EKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPL-PRGDAPVDKV 989
             K       K+        KE      +   +     P    P  T P  P+  AP    
Sbjct: 676  LKEPAPTTPKKPA-----PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 730

Query: 990  ELSEDSPNSEQDLE-KLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAK- 1047
            E +  +P        K    + P  P P   +     G T+T S     T  KE      
Sbjct: 731  EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 790

Query: 1048 ---ASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQG 1104
               A +    P+P T  T  P     S  T +  P T   S DE   E   +     L+ 
Sbjct: 791  KEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN 850

Query: 1105 SSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLP 1164
            S   P       P + K    T  K   ++  +D R   +   +A K   +   T+    
Sbjct: 851  SPKEPGVPTTKTPAATKPEMTTTAK--DKTTERDLRTTPETTTAAPKMTKETATTTEKTT 908

Query: 1165 ASKIPA 1170
             SKI A
Sbjct: 909  ESKITA 914


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 64.3 bits (155), Expect = 7e-10
 Identities = 104/477 (21%), Positives = 162/477 (33%), Gaps = 61/477 (12%)

Query: 885  PQEATSTLQMS--QAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQ 942
            P  A+ T++ +  ++P+ P        ++S  I E HSVS    + S   +       R+
Sbjct: 122  PSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRK 181

Query: 943  NLDHYNG---KEFEKLLE--EAQANIMKSIPNLEMP---PATGPLPRGDAPVDKVELSED 994
                 N    +E +K L+  + + N  K  P  + P    A   L  GD  V   + S  
Sbjct: 182  IKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTT 241

Query: 995  SPNSEQDLEKLGGKSP--PPPPPPPRRSYLPGSGLT-----------TTRSGDVVYTGRK 1041
              N      K+    P  P P  PP       + LT           TT +     T  K
Sbjct: 242  QHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGK 301

Query: 1042 ENITA--------KASSEDAGPSPQTRA---------TKYPA------------EEPASA 1072
            E  T+        K S++D  P+ +  A         TK PA            +EPAS 
Sbjct: 302  EKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAST 361

Query: 1073 WTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKN-RPGTLDKPG 1131
                P P T  S+    +E        A       AP T++ P P + K   P T  +P 
Sbjct: 362  TPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA 421

Query: 1132 KQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNL 1191
              +    P   ++   +  K      PT+P  PA   P     +      P++   +   
Sbjct: 422  PTTTKSAPTTPKEPAPTTPKKPA---PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT 478

Query: 1192 PNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNG 1251
            P  PA        P +P+   P       P+ +    K  S T   +    +        
Sbjct: 479  PKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT----KEPSPTTPKEPAPTTTKSAPTTT 534

Query: 1252 RAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSK-ATPSTAKE 1307
            + P P +  S+P +P              T   P+ T+ K    ++ K   P+T KE
Sbjct: 535  KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 591



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 80/369 (21%), Positives = 122/369 (33%), Gaps = 43/369 (11%)

Query: 957  EEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPP---- 1012
            +E     +KS P     PA  P     AP       E +P + ++      K P P    
Sbjct: 364  KEPTPTTIKSAPTTPKEPA--PTTTKSAPTTP---KEPAPTTTKEPAPTTPKEPAPTTTK 418

Query: 1013 -PPPPPRRSY--LPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPA--- 1066
             P P   +S    P     TT       T ++   T         P      TK PA   
Sbjct: 419  EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT 478

Query: 1067 -EEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPG 1125
             +EPA      P P T         +E       A       +P T + P P + K+ P 
Sbjct: 479  PKEPAPTAPKKPAPTTPKEPAPTTPKEP------APTTTKEPSPTTPKEPAPTTTKSAPT 532

Query: 1126 TLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSS 1185
            T  +P   +    P   ++ + +  K      PT+P  PA   P     +      P++ 
Sbjct: 533  TTKEPAPTTTKSAPTTPKEPSPTTTKEPA---PTTPKEPAPTTPKKPAPTTPKEPAPTTP 589

Query: 1186 GDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFS 1245
             +    P P  TK    + P  P    P  +A   P         + LT T        +
Sbjct: 590  KE----PAPTTTKKPAPTTPKEPAPTTPKETAPTTP---------KKLTPTTPEKLAPTT 636

Query: 1246 PQSQNGRAPPPLSFSS----SPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSK-A 1300
            P+      P  L+ ++    +P +P         A    T   P+ T+ K    ++ K  
Sbjct: 637  PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 696

Query: 1301 TPSTAKETS 1309
             P+T KET+
Sbjct: 697  APTTPKETA 705



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 80/364 (21%), Positives = 119/364 (32%), Gaps = 39/364 (10%)

Query: 957  EEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPPPP 1016
            E A     K  P     PA    P+  AP    +L+  +P      EKL   +P  P P 
Sbjct: 591  EPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTP------EKLAPTTPEKPAPT 643

Query: 1017 PRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPA----EEPA-- 1070
                  P    TT               T KA++ +    P     K PA    +EPA  
Sbjct: 644  TPEELAP----TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 699

Query: 1071 -----SAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPG 1125
                 +  TP     TT         ++   K +A          T   P P + K    
Sbjct: 700  TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 759

Query: 1126 TLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSS 1185
            T  K    +  ++P       G+A  +  +  PT+P  PA K   L+P++ K  +  S++
Sbjct: 760  TTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPKKPAPK--ELAPTTTKGPT--STT 814

Query: 1186 GDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFS 1245
             D      P  T P+    P       PA +    P  +   +   + T      H S  
Sbjct: 815  SDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD 874

Query: 1246 PQSQNGRA-PPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPST 1304
              +    A P P +  +SP  P           G  T  TP+ T  +    +  K T   
Sbjct: 875  ESTPELSAEPTPKALENSPKEP-----------GVPTTKTPAATKPEMTTTAKDKTTERD 923

Query: 1305 AKET 1308
             + T
Sbjct: 924  LRTT 927



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 69/306 (22%), Positives = 100/306 (32%), Gaps = 20/306 (6%)

Query: 871  PAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSI 930
            PA   P  A++P  P+E   T     AP +P+ P   +       +E    + K  A + 
Sbjct: 664  PAPTTPK-AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP------KETAPTTPKGTAPTT 716

Query: 931  EKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPL-PRGDAPVDKV 989
             K       K+        KE      +   +     P    P  T P  P+  AP    
Sbjct: 717  LKEPAPTTPKKPA-----PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 771

Query: 990  ELSEDSPNSEQDLE-KLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAK- 1047
            E +  +P        K    + P  P P   +     G T+T S     T  KE      
Sbjct: 772  EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 831

Query: 1048 ---ASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQG 1104
               A +    P+P T  T  P     S  T +  P T   S DE   E   +     L+ 
Sbjct: 832  KEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN 891

Query: 1105 SSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLP 1164
            S   P       P + K    T  K   ++  +D R   +   +A K   +   T+    
Sbjct: 892  SPKEPGVPTTKTPAATKPEMTTTAK--DKTTERDLRTTPETTTAAPKMTKETATTTEKTT 949

Query: 1165 ASKIPA 1170
             SKI A
Sbjct: 950  ESKITA 955


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 103/476 (21%), Positives = 163/476 (34%), Gaps = 65/476 (13%)

Query: 885  PQEATSTLQMSQAPQ----SPQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEK 940
            P+  T +   S AP+    +P++P     ++   ++E  S S     + + K E   E K
Sbjct: 201  PRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSD---ILKVPKPEPIPEPK 257

Query: 941  RQNLDHYNGKEFEKLLEEAQANIM---KSIPNLEMPPATGPLPRGDAPVDKVE-LSEDSP 996
              + +  + KE EK     ++      +S      P  T P  R  +           SP
Sbjct: 258  EPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSP 317

Query: 997  NSEQDLEKLGGKSPP---PPPPPPRRSYLP-----GSGLTTTRSGDVVYTGRKENITAKA 1048
                   +   ++PP   PPPP  RRS  P      S  + + S     + R  +   K 
Sbjct: 318  RRRPSPRR---RTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKP 374

Query: 1049 SSEDAGPSPQTRATKYPAEEPASAWTPSPP----PVTTSSSKDEEEEEEEGDKI------ 1098
                + P  +TR     A  P     PSPP    P T  S   ++       ++      
Sbjct: 375  PKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGR 434

Query: 1099 ----MAELQGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQS---KLQDPRQYRQANGSAKK 1151
                + + +G+      S  P P   +      DK GK +    +Q  RQYR+ N  +  
Sbjct: 435  TSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSS 494

Query: 1152 SGGDFKPTSPSLPA---------------SKIPALSPSSGKSSSLPSSSGDSSNLPNPPA 1196
              G    +    P                S   + SPS  K     S  G     P+PP 
Sbjct: 495  DSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPP 554

Query: 1197 TKPSIASNPLSP------QTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQN 1250
            T+   + +P  P       T PP       P         +      + +  S  P+ + 
Sbjct: 555  TRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRT 614

Query: 1251 GRAPPPLSFSSSP-PSPASSVSLN----QGAKGTRTIHTPSLTSYKAQNGSSSKAT 1301
               PPP    +SP P P   VS +    Q +       +PSL+S   +  S S++T
Sbjct: 615  ASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRST 670



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 66/295 (22%), Positives = 100/295 (33%), Gaps = 23/295 (7%)

Query: 938  EEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPN 997
            E++R    H    E  +    + +      P       +    R  +P         SP+
Sbjct: 503  EDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPS 562

Query: 998  SEQDLEKLGGKSPPP----PPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDA 1053
                  +    +PPP    P PPPRR        +  R    +      +   K  +   
Sbjct: 563  PAPPPRRRRTPTPPPRRRTPSPPPRRR-----SPSPRRYSPPIQRRYSPSPPPKRRTASP 617

Query: 1054 GPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSR 1113
             P P+ RA+  P+  P    + SPPP   SS   +        K     +GSS +  T  
Sbjct: 618  PPPPKRRAS--PSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSK---HRKGSSPSRSTRE 672

Query: 1114 MPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIP---- 1169
               P   K    +      Q+    P   R A+ S ++       T P    S+ P    
Sbjct: 673  ARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKK 732

Query: 1170 ---ALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIP 1221
               A SPS  +S    SSS   S  P P A KP    +P+  Q+ P  + +  +P
Sbjct: 733  IKKAASPSP-QSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQS-PSTNWSPAVP 785



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 74/347 (21%), Positives = 119/347 (34%), Gaps = 39/347 (11%)

Query: 984  APVDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTG---- 1039
            A  D V+         Q      G S       P+RS++    +   R      +     
Sbjct: 474  AAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSP 533

Query: 1040 -RKENITAKASSEDAGPSP---QTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEG 1095
             +++  T+        PSP   + R +  PA  P    TP+PPP   + S          
Sbjct: 534  RKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSP 593

Query: 1096 DKIMAELQG--SSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSG 1153
             +    +Q   S   P   R   P     R  +   P K+     P   ++++   K+  
Sbjct: 594  RRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRR- 652

Query: 1154 GDFKPTSPSLPASKIPALSPS-SGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSP-QTG 1211
                  SPSL +      SPS S + +  P  +   S  P P A + S +  P+    + 
Sbjct: 653  ------SPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASS 706

Query: 1212 PPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQN-----------GRAPPPLSFS 1260
             P    S  PS S   ++  S T   K    + SP  Q+           G   P     
Sbjct: 707  SPQRRQS--PSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKP 764

Query: 1261 SSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKE 1307
             +PPSP  S S         T  +P++   KA++ + S + P  + +
Sbjct: 765  PAPPSPVQSQS-------PSTNWSPAVPVKKAKSPTPSPSPPRNSDQ 804



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 42/160 (26%), Positives = 65/160 (40%), Gaps = 19/160 (11%)

Query: 965  KSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRSYLPG 1024
            +S+     P A  P     AP   V+    S N    +     KSP P P PPR S   G
Sbjct: 751  RSVSGSPEPAAKKP----PAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEG 806

Query: 1025 SGLTTTRSGDVVY----------TGRKENITAKASSEDAGPSPQTRATKYPA-EEPASAW 1073
             G    +  D  +            +KE   A A++    P+    AT   A EEP +A 
Sbjct: 807  GGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAA- 865

Query: 1074 TPSPPPVTTSSSKD--EEEEEEEGDKIMAELQGSSGAPQT 1111
             P P   T S ++D  ++ E+   +K +  ++ +  +PQ+
Sbjct: 866  -PEPKKETESEAEDNLDDLEKHLREKALRSMRKAQVSPQS 904



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 87/414 (21%), Positives = 143/414 (34%), Gaps = 42/414 (10%)

Query: 906  NGSAMQSLFIEEIHSVSAKNRAVSIEK--AEKKWEEKRQNLDHYNGKEFEKLLEEAQANI 963
            N + + S F+E +     K R +  EK  + KK +E +   D    +   +  E +++  
Sbjct: 115  NIAGIPSAFLE-LKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPR 173

Query: 964  MKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPP-------PP 1016
             +         +  P PR  +   + E       S +   K    SP P         P 
Sbjct: 174  RRK--------SRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPE 225

Query: 1017 PRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPAS--AWT 1074
            P       S    T + D++   + E I      E   PSP+  + K   +E     + +
Sbjct: 226  PSVKVKEPSVQEATSTSDILKVPKPEPIP-----EPKEPSPEKNSKKEKEKEKTRPRSRS 280

Query: 1075 PSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQS 1134
             S     T S            +  +        P   R P P   +  P  +  P +  
Sbjct: 281  RSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRR-RTPPRRMPPPPRHR 339

Query: 1135 KLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNP 1194
            + + P + R+   SA  SG     +S S   S+ P   P   ++SS P  +   S    P
Sbjct: 340  RSRSPVR-RRRRSSASLSGSS---SSSSSSRSRSPPKKPPK-RTSSPPRKTRRLS----P 390

Query: 1195 PATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAP 1254
             A+ P     P  P T PP    S  P  SN + K +     G+        +    R  
Sbjct: 391  SASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRES 450

Query: 1255 PPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSL---TSYKAQNGSSSKATPSTA 1305
            P    S +P      +S ++  KG +     S+     Y+ QN  SS  + S++
Sbjct: 451  P----SPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSS 500



 Score = 39.3 bits (90), Expect = 0.025
 Identities = 92/409 (22%), Positives = 134/409 (32%), Gaps = 93/409 (22%)

Query: 2   EENESQKCEPCLPYSADRRQMQEQGKGNLHVTSPEDAECRRTKERLSNGNS-RGSVSKSS 60
           +E E +K  P       R + + + +      SP     RR     S   S R   S   
Sbjct: 267 KEKEKEKTRP-------RSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRR 319

Query: 61  RNIPRRHT----LGGP--------------RSSKEILGMQTSEMDRKREAFLEHLKQKYP 102
           R  PRR T    +  P              RSS  + G  +S    +  +      +K P
Sbjct: 320 RPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRS----PPKKPP 375

Query: 103 HHASAIMGHQERLRDQTRSPKLSHSPQPPSLGDPVEHLSETSADSLEAMSEGDAPTPFSR 162
              S+      RL      P+  H P PP+   P    S               PTP  +
Sbjct: 376 KRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHS---------------PTP-QQ 419

Query: 163 GSRTRASLPVVRSTNQTKERSLGVLYLQYGDETKQLRMPNEITSADTIRALFVSAFPQQL 222
            +RTR S       + +  R+ G +    G E ++   P     A   R + +S   +  
Sbjct: 420 SNRTRKS-----RVSVSPGRTSGKVTKHKGTEKRESPSP-----APKPRKVELSESEEDK 469

Query: 223 TMKMLESPSVAIYIKDESRNVYYELNDVRNIQDRSLLKVYNKDP--AHAFN--------H 272
             KM  + SV      + R  Y   N   +    S     ++ P  +H  N        H
Sbjct: 470 GGKMAAADSV------QQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRH 523

Query: 273 TP-KTMNGDMRMQRELVYARGDGPGAPRPGSTAHPPHAIPNSPP-----STPVPHSMPPS 326
           +P ++ +   R +++    RG    +P P  T       P  PP      TP P    PS
Sbjct: 524 SPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPS 583

Query: 327 PSRIPYGGTRSMVVPGNATIPRDRISSLPVSRPISPSPSAILERRDVKP 375
           P             P     P  R  S P+ R  SPSP    +RR   P
Sbjct: 584 P-------------PPRRRSPSPRRYSPPIQRRYSPSPPP--KRRTASP 617


>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
            sapiens]
          Length = 247

 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 54/212 (25%), Positives = 70/212 (33%), Gaps = 14/212 (6%)

Query: 1006 GGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYP 1065
            GG  P  PPPPP +   P         G     G+ E    +  ++  GP P     + P
Sbjct: 43   GGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERP 102

Query: 1066 AEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPG 1125
              +  +    +PPP      K E    + G+    +       P     P P       G
Sbjct: 103  PPQGGNQSQGTPPP----PGKPERPPPQGGN----QSHRPPPPPGKPERPPPQGGNQSQG 154

Query: 1126 TLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSS 1185
                PGK      P Q    + SA+   G  KP  P       P   P  GK    P + 
Sbjct: 155  PPPHPGKPEG--PPPQEGNKSRSARSPPG--KPQGPPQQEGNKPQGPPPPGKPQGPPPAG 210

Query: 1186 GDSSNLPNPPATKPSIASNPLSPQTGPPAHSA 1217
            G+      PPA KP     P  PQ G P   A
Sbjct: 211  GNPQQPQAPPAGKPQ--GPPPPPQGGRPPRPA 240


>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
            homolog, Drosophila); translocated to, 1 [Homo sapiens]
          Length = 559

 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 80/327 (24%), Positives = 118/327 (36%), Gaps = 24/327 (7%)

Query: 898  PQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQN-LDHYNGKEFEKLL 956
            P  P IP++  +          S  A   +    K  K  +E R+        K   K L
Sbjct: 159  PMLPTIPLSAFSDPKKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKEL 218

Query: 957  EEAQANIMKSIPNLEMPPATGPLPRGD-APVDKVELSEDSPN-SEQDLEKLGGKS--PPP 1012
            E  QA   KS  +       G LP+ + AP  K    E      E  LE    K   PPP
Sbjct: 219  EREQA---KSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPP 275

Query: 1013 PPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRAT-----KYPAE 1067
            PPPPPR S    S    T         +++  ++K S    G SP+T ++     K PA+
Sbjct: 276  PPPPPRAS----SKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAK 331

Query: 1068 EPAS-----AWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKN 1122
            + +S         S P     + + EE   E+     +E   SS +  +S       +  
Sbjct: 332  DKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDF 391

Query: 1123 RPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKS--SS 1180
             P      G    + +  Q  +++     SG +    +     S++      S  S  SS
Sbjct: 392  EPSQNHSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADSS 451

Query: 1181 LPSSSGDSSNLPNPPATKPSIASNPLS 1207
            LPS        P PP +K S   +P S
Sbjct: 452  LPSREPPPPQKPPPPNSKVSGRRSPES 478



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 56/254 (22%), Positives = 90/254 (35%), Gaps = 21/254 (8%)

Query: 1055 PSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRM 1114
            P    + TK  +  P     P PPP   +SSK     +        + + SS        
Sbjct: 254  PKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSS-------- 305

Query: 1115 PVPMSAKNRPGTLDKPGKQSKLQDPRQYRQAN---GSAKKSGGDFKPTSPSLPASKIPAL 1171
                 +++ PGT  +    S   D +  +  +   G   K+  + +    +L   +  + 
Sbjct: 306  ---KGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKALEVEESNSE 362

Query: 1172 SPSSGKSSSL---PSSSGDSSNLPNPPATKPSI--ASNPLSPQTGPPAHSASLIPSVSNG 1226
              +S KS S    PS+S  SS+  +    +PS   +  PL           S     S+G
Sbjct: 363  DEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDSSSG 422

Query: 1227 SLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPS 1286
              +    T+ G+   LSFS    +  A   L  S  PP P      N    G R+  + S
Sbjct: 423  E-EAAGKTNPGRDSRLSFSDSESDNSADSSLP-SREPPPPQKPPPPNSKVSGRRSPESCS 480

Query: 1287 LTSYKAQNGSSSKA 1300
                  + G+  KA
Sbjct: 481  KPEKILKKGTYDKA 494



 Score = 30.8 bits (68), Expect = 8.9
 Identities = 33/149 (22%), Positives = 49/149 (32%), Gaps = 4/149 (2%)

Query: 418 PDHIIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHR 477
           P  +   HR   R  S   + S + E    +S  +  SRK  +  LP      PP +  +
Sbjct: 194 PHKVTKEHRERPRKDSESKSSSKELEREQAKSS-KDTSRKLGEGRLPKEEKAPPPKAAFK 252

Query: 478 VSDLRMIDMHAHYNAHG---PPHTMQPDRASPSRQAFKKEPGTLVYIEKPRSAAGLSSLV 534
              + + +      +     PP    P RAS  R A    P      +K  S+ G  S  
Sbjct: 253 EPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAP 312

Query: 535 DLGPPLMEKQVFAYSTATIPKDRETSEKM 563
              P       F+       K     EK+
Sbjct: 313 GTSPRTSSSSSFSDKKPAKDKSSTRGEKV 341


>gi|41281612 zinc finger protein 828 [Homo sapiens]
          Length = 812

 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 70/303 (23%), Positives = 109/303 (35%), Gaps = 23/303 (7%)

Query: 973  PPATGPLPRGDA-PVDKVELSEDSPNSEQDLEKLGG----KSPPPPPPPPRRSYLPGSGL 1027
            P  + PLP     P +  E  +  P    + +KLG     +SP P P  P     PGS +
Sbjct: 105  PVKSPPLPEHQKIPCNSAE-PKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSVV 163

Query: 1028 TTTRSGDVVYT--GRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSS 1085
            +      +      +  ++++    +        +    P+ EP      SP  V  + S
Sbjct: 164  SPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLS 223

Query: 1086 KDEEEEEEEGDKIMAELQGSSG-APQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQ 1144
              + +++    + +     SS  +P  +  P P      P    +  K ++   P   + 
Sbjct: 224  NPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPS--PAASPESRKSARTTSPEPRKP 281

Query: 1145 ANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASN 1204
            +   + +    F   SP  P    PA+SP S K    P   G     P P  + PS +S 
Sbjct: 282  SPSESPEPWKPFPAVSPE-PRRPAPAVSPGSWK----PGPPGS----PRPWKSNPSASSG 332

Query: 1205 PLSPQTGPPAHSASL---IPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSS 1261
            P  P    P+ S      IPSVS G  K      +      S SP S       P S+ S
Sbjct: 333  PWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKS 392

Query: 1262 SPP 1264
             PP
Sbjct: 393  GPP 395



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 84/332 (25%), Positives = 116/332 (34%), Gaps = 62/332 (18%)

Query: 994  DSPNSEQDLEKLGGKSPPPPPPPP------RRSYLPGSGLTTTRSGDVVYTGRKENITAK 1047
            D P ++ + E    KSPP P              +P   + T + G V+           
Sbjct: 93   DKPKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVL----------- 141

Query: 1048 ASSEDAGPSPQTRATKYPAEEPASAWTPS--PPPVTTSSSKDEEEEEEEGDKIMAELQGS 1105
             S E   P+P    T    ++P S  +P    P  +   SK       E  K +   +  
Sbjct: 142  -SPESPKPTP---LTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQ 197

Query: 1106 SGAPQTS---RMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPS 1162
              AP  S   + P P+S ++   TL  P  Q +   P      + S+        P SP 
Sbjct: 198  KLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASS--------PESPV 249

Query: 1163 LPAS-----KIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSA 1217
            L AS       PA SP S KS+   S        P P    PS +  P  P         
Sbjct: 250  LAASPEPWGPSPAASPESRKSARTTS--------PEPRKPSPSESPEPWKPFPAVSPEPR 301

Query: 1218 SLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNG---RAPPPLSFSSSPPSPASSVSLNQ 1274
               P+VS GS K       G       +P + +G    A P  S S  P  P  SVS   
Sbjct: 302  RPAPAVSPGSWK---PGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGP 358

Query: 1275 GAKGTRTIHTPSLTSYKAQNGSSSKATPSTAK 1306
                     TPS++S    +  SS  +PS+ K
Sbjct: 359  WKP------TPSVSS---ASWKSSSVSPSSWK 381


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 94/358 (26%), Positives = 121/358 (33%), Gaps = 54/358 (15%)

Query: 973  PPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPP---PPPPPRRSYLPGSGLTT 1029
            P AT P P+G       + +  +P +     K G  +PPP   P  P      P  GL T
Sbjct: 1129 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1188

Query: 1030 TRSGDVVYTGRKENITAKASSEDAGP--SPQTRATKYPAEEPASAWTPSPPPVTTSSSKD 1087
                    T      + K       P  +P T A   P+ +   A TPSP    T+ +  
Sbjct: 1189 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLA-TPSPKGAPTTPA-- 1245

Query: 1088 EEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANG 1147
                        A      G P T   P P  A   P     P  +  L  P      N 
Sbjct: 1246 ------------ATPPSPKGGPAT---PPPKGAPTPPAA-TPPSLKGGLATPPHKGAPNP 1289

Query: 1148 SA----KKSGGDFKPTSPSLPASKIPALSPSSGKSS-SLPSSSGDSSNLPNPPA-TKPSI 1201
            +        GG    TSP   A   PA +P S K S   P   G     P PPA T PS 
Sbjct: 1290 AVVTPPSPKGG--PATSPPKGAPTPPAATPPSPKGSPGTPPPKG----APTPPAVTPPSP 1343

Query: 1202 ASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPP------ 1255
               P  P T P +      PS   G     + T + KG      P  + G A P      
Sbjct: 1344 KGTPTLPATTPSSKGGPTTPSSKEGPTP-PAATPSHKGGPAMTPPSPKRGPAIPSPKGDP 1402

Query: 1256 ------PLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSY---KAQNGSSSKATPST 1304
                  PLS   +P +P +       +KG  T   P++T     KA   S+ K  P+T
Sbjct: 1403 TSPAVIPLSPKKAPATPVTREGAATPSKGDLT--PPAVTPVSLKKAPATSAPKGGPAT 1458



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 120/496 (24%), Positives = 183/496 (36%), Gaps = 81/496 (16%)

Query: 872  AQNLPHVASSPAVPQEATSTL----QMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRA 927
            ++N P VA SP       +TL    ++ ++  SP +P  G+   +  ++ I   SA    
Sbjct: 705  SENCP-VAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPV 763

Query: 928  VSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPP----ATGP-LPRG 982
             S  K E   E+   +    +      L +      +   P  + PP    + GP  P G
Sbjct: 764  ASSPK-ECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIG 822

Query: 983  D--APVDKVELSEDSPNSEQDLEKLGGKSPP-----PPPPPPRRSYLPGSGLTTTRSGDV 1035
            +  +PV  VE S    NS   L   G K  P     P PP P+ +  P +   T  S   
Sbjct: 823  NLSSPVSPVEASFLPENS---LSFQGSKDSPATTHSPTPPSPKGAPTPSA--VTPLSPKG 877

Query: 1036 VYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEG 1095
            V    KE            P+P      +P E PA+      P ++ +SS  ++      
Sbjct: 878  VTLPPKET-----------PTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPA 926

Query: 1096 DKIMAELQGSSGAPQTSRMPVPMSAKNRPGTLD-KPGKQSKLQDPRQYRQANGSAKKSGG 1154
             K +       GAP T     P S K  P T   K         P   +    +    G 
Sbjct: 927  PKGIPASPSPKGAP-TPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGA 985

Query: 1155 DFKPTS--------PSLPASK----IPALSPSSGKSSSLPSSSGDSSNLP---NPPATKP 1199
               P +        P+ P+ K     PA++P S K S   +     ++ P    PP+ K 
Sbjct: 986  PTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKG 1045

Query: 1200 SIASNPL-------------SPQTGPPAHS---ASLIPSVSNGSLKFQSLTHTGKGHHL- 1242
            S A+ PL             SP+ GP   S   A   P+ +  S K    T + KG  + 
Sbjct: 1046 SPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMP 1105

Query: 1243 --SFSPQSQNGRAPP-----PLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNG 1295
              +  P  + G A P     P + +++PPSP   ++     KG  T  TP+ T    + G
Sbjct: 1106 PAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLA-TPPPKGAPT--TPAATPPSPKGG 1162

Query: 1296 SSS---KATPSTAKET 1308
             ++   K  P+T   T
Sbjct: 1163 LATPPPKGAPTTPAAT 1178



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 93/385 (24%), Positives = 130/385 (33%), Gaps = 65/385 (16%)

Query: 973  PPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPP---PPPPPRRSYLPGSGLTT 1029
            P AT P P+G       + +  +P +     K G  +PPP   P PP         GL T
Sbjct: 1221 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLAT 1280

Query: 1030 TRSGDVVYTGRKENITAKASSEDAGP--SPQTRATKYPAEEPASA----------WTPSP 1077
                   + G          S   GP  SP   A   PA  P S             P+P
Sbjct: 1281 PP-----HKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTP 1335

Query: 1078 P-------------PVTTSSSKD--EEEEEEEGDKIMAELQGSSGAPQTS--------RM 1114
            P             P TT SSK        +EG    A      G P  +         +
Sbjct: 1336 PAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAI 1395

Query: 1115 PVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTS---------PSLPA 1165
            P P      P  +    K++    P       G+A  S GD  P +         P+  A
Sbjct: 1396 PSPKGDPTSPAVIPLSPKKA----PATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSA 1451

Query: 1166 SKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKP-SIASNPLSPQTGPPAHSASLIPSVS 1224
             K    +PSS    +LP+ +  S     PPA K  + +S+P      P    A  +P+V 
Sbjct: 1452 PKGGPATPSSKGDPTLPAVTPPSPK--EPPAPKQVATSSSPKKAPATPAPMGAPTLPAVI 1509

Query: 1225 NGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHT 1284
              S K    T + +   ++ +    + + P  L+   +   PA +V      K T  I T
Sbjct: 1510 PSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTV---PSPKKTPAIPT 1566

Query: 1285 PS---LTSYKAQNGSSSKATPSTAK 1306
            P     T    +  S    TPST K
Sbjct: 1567 PKEAPATPSSKEASSPPAVTPSTYK 1591



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 88/362 (24%), Positives = 127/362 (35%), Gaps = 48/362 (13%)

Query: 973  PPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPP---PPPPPRRSYLPGSGLTT 1029
            P AT P P+G       + +  +P +     K G  +P P   P  P      P  GL T
Sbjct: 1152 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT 1211

Query: 1030 TRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEE 1089
                    T      + K     A PSP+   T   A  P+    P+ PP   + +    
Sbjct: 1212 PSPKGAPTTPAATPPSPKGGL--ATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAA 1269

Query: 1090 EEEEEGDKIMAELQGSSGAPQTSRMP-----VPMSAKNRPGTLDKPGKQSK-LQDPRQYR 1143
                        L+G    P     P      P S K  P T    G  +     P   +
Sbjct: 1270 TPPS--------LKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPK 1321

Query: 1144 QANGSAKKSGGDFKPTSPSL--PASK----IPALSPSSGKSSSLPSSSGDSSNLPNPPAT 1197
             + G+    G    PT P++  P+ K    +PA +PSS    + PSS       P PPA 
Sbjct: 1322 GSPGTPPPKGA---PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEG----PTPPAA 1374

Query: 1198 KPSI----ASNPLSPQTGPPAHSASLIPS----VSNGSLKFQSLTHTGKGHHLSFSPQSQ 1249
             PS     A  P SP+ GP   S    P+    +     K  +   T +G     +  S+
Sbjct: 1375 TPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREG----AATPSK 1430

Query: 1250 NGRAPPPLSFSSSPPSPASSV----SLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTA 1305
                PP ++  S   +PA+S          +KG  T+   +  S K        AT S+ 
Sbjct: 1431 GDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSP 1490

Query: 1306 KE 1307
            K+
Sbjct: 1491 KK 1492



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 119/547 (21%), Positives = 189/547 (34%), Gaps = 93/547 (17%)

Query: 792  KGTDAAQAAQYMAMEKATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSEVVP---LSGMM 848
            KG     A   ++++KA A    K       + G P      P   K    P    +   
Sbjct: 1430 KGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSS 1489

Query: 849  VRHAQSSPVVIQPSQHSVALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQS--PQIPMN 906
             + A ++P  +        + +  + +P   SS   P   T+TL   + P +  P+  + 
Sbjct: 1490 PKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALI 1549

Query: 907  GSAMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQNLDHYNGKEFEKLL---------- 956
              AM     ++  ++     A +   +++           Y G    K L          
Sbjct: 1550 PPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPS 1609

Query: 957  -EEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELS--EDSPNSEQDLE-KLGGKSPPP 1012
             +EA      + P+ E  PAT P P+G      V  S  +DSP S   +  K+G   P  
Sbjct: 1610 PKEAPTPPAVTPPSPEKGPAT-PAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQA 1668

Query: 1013 PPPPPRRSYLPGSGLTTTR---------SGDVVYTGRKENITAKASSEDAGPSPQTRATK 1063
                P +      G T  +         S  ++    ++    K SS  + P     + K
Sbjct: 1669 SKGLPAKK-----GPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAK 1723

Query: 1064 YPAEEPASAWTPSPP-PVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKN 1122
              ++ P S   P+P  PV   SSK  + ++       +       AP  S+   P++A  
Sbjct: 1724 NGSKGPLSTVAPAPLLPVQKDSSKTAKGKDA------SHSPKGPLAPPESKASTPLTAAA 1777

Query: 1123 RPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLP 1182
                L KP                 SA  S     P S  L  S +P L P   K   LP
Sbjct: 1778 FEKVLPKPE----------------SASVSAAPSPPVSLPLAPSPVPTLPP---KQQFLP 1818

Query: 1183 SSSG---DSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKG 1239
            SS G   +S + P  PA +  +   PL P            P   +G + FQS+      
Sbjct: 1819 SSPGLVLESPSKPLAPADEDELL--PLIP------------PEPISGGVPFQSV------ 1858

Query: 1240 HHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSK 1299
              L   P  ++   P P       PS    V+ N    GT +    S+   + Q+  S++
Sbjct: 1859 --LVNMPTPKSAGIPVP------TPSAKQPVTKNNKGSGTESDSDESVPELEEQD--STQ 1908

Query: 1300 ATPSTAK 1306
            AT   A+
Sbjct: 1909 ATTQQAQ 1915



 Score = 37.4 bits (85), Expect = 0.095
 Identities = 25/75 (33%), Positives = 30/75 (40%), Gaps = 5/75 (6%)

Query: 295  PGAPRPGSTAHPPHAIPNSP---PSTPVPHSMPPSPSRIPYG--GTRSMVVPGNATIPRD 349
            P +P P     PP A P SP   P+TP P   P  P+  P    G  +   P  A  P  
Sbjct: 931  PASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPA 990

Query: 350  RISSLPVSRPISPSP 364
                 P   P +PSP
Sbjct: 991  ATPPSPKGGPATPSP 1005



 Score = 37.4 bits (85), Expect = 0.095
 Identities = 28/78 (35%), Positives = 34/78 (43%), Gaps = 9/78 (11%)

Query: 294  GPGAPRPGSTAHPPHAIPNSP---PSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDR 350
            GP  P P     PP A P SP   P+TP P   P  P+  P     S   P     P+  
Sbjct: 976  GPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGS---PAATPFPKG- 1031

Query: 351  ISSLPVSRPISP--SPSA 366
             S+ P + P SP  SP+A
Sbjct: 1032 ASTPPAATPPSPKGSPAA 1049



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 26/81 (32%), Positives = 35/81 (43%), Gaps = 8/81 (9%)

Query: 291  RGDGPGAPRPGSTAHPPHAIP----NSPPSTPVPHSMPPSPSRI---PYGGTRSMVVPGN 343
            +G     P P   + PP A P     SP +TP+P   P +P+     P GG  +  + G 
Sbjct: 1020 KGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA 1079

Query: 344  ATIPRDRISSLPVSRPISPSP 364
             T P     S P   P +PSP
Sbjct: 1080 PTPPAATPPS-PKGGPATPSP 1099



 Score = 34.7 bits (78), Expect = 0.62
 Identities = 26/78 (33%), Positives = 30/78 (38%), Gaps = 10/78 (12%)

Query: 294  GPGAPRPGSTAHPPHAIPNSP---PSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDR 350
            GP  P P     PP A P SP   P+TP P   P  P+  P         P     P   
Sbjct: 953  GPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAP--- 1009

Query: 351  ISSLPVSRPISP--SPSA 366
              + P   P SP  SP+A
Sbjct: 1010 --TPPAVTPPSPKGSPAA 1025



 Score = 34.3 bits (77), Expect = 0.80
 Identities = 24/72 (33%), Positives = 28/72 (38%), Gaps = 8/72 (11%)

Query: 294  GPGAPRPGSTAHPPHAIPNSP---PSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDR 350
            GP  P       PP A P SP   P+TP P   P  P+  P          G AT P   
Sbjct: 1070 GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATP-----PSPKGGLATPPHKG 1124

Query: 351  ISSLPVSRPISP 362
              + P + P SP
Sbjct: 1125 APTTPAATPPSP 1136



 Score = 34.3 bits (77), Expect = 0.80
 Identities = 24/76 (31%), Positives = 29/76 (38%), Gaps = 5/76 (6%)

Query: 294  GPGAPRPGSTAHPPHAIPNSP---PSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDR 350
            GP    P     PP A P SP   P TP P   P  P+  P     +  +P  AT P  +
Sbjct: 1300 GPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLP--ATTPSSK 1357

Query: 351  ISSLPVSRPISPSPSA 366
                  S    P+P A
Sbjct: 1358 GGPTTPSSKEGPTPPA 1373



 Score = 32.3 bits (72), Expect = 3.1
 Identities = 24/81 (29%), Positives = 30/81 (37%), Gaps = 15/81 (18%)

Query: 294  GPGAPRPGSTAHPPHAIPNSPPSTPV-----------PHSMPPSPSRIPYGGTRSMVVPG 342
            GP  P P     PP   P SP  +P            P + PPSP   P     + +  G
Sbjct: 999  GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSP---AATPLPKG 1055

Query: 343  NATIPRDRISSLPVSRPISPS 363
              T P   + S P   P +PS
Sbjct: 1056 APTTPAATLPS-PKGGPATPS 1075



 Score = 32.3 bits (72), Expect = 3.1
 Identities = 25/69 (36%), Positives = 30/69 (43%), Gaps = 6/69 (8%)

Query: 296  GAPRPGSTAHPPHAIPNSPPSTPVPHSM-PPSPSRIPYGGTRSMVVPGNATIPRDRISSL 354
            GAP P     PP     SP   P P ++ PPSP +    G  +    G  T P    SSL
Sbjct: 1592 GAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEK----GPATPAPKGTPTSPPVTPSSL 1647

Query: 355  PVSRPISPS 363
              S P SP+
Sbjct: 1648 KDS-PTSPA 1655



 Score = 32.0 bits (71), Expect = 4.0
 Identities = 23/72 (31%), Positives = 28/72 (38%), Gaps = 8/72 (11%)

Query: 294  GPGAPRPGSTAHPPHAIPNSPP---STPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDR 350
            GP  P P     PP A P SP    +TP     P +P+  P          G AT P   
Sbjct: 1093 GPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATP-----PSPKGGLATPPPKG 1147

Query: 351  ISSLPVSRPISP 362
              + P + P SP
Sbjct: 1148 APTTPAATPPSP 1159



 Score = 32.0 bits (71), Expect = 4.0
 Identities = 23/80 (28%), Positives = 31/80 (38%), Gaps = 13/80 (16%)

Query: 295  PGAPRPGSTAHPPHAIPNSPPSTP---------VPHSMPPSPSRIPYGGTRSMVVPGNAT 345
            P +P+ G    PP   P  P +TP          PH   P+P+ +    T      G AT
Sbjct: 1248 PPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVV----TPPSPKGGPAT 1303

Query: 346  IPRDRISSLPVSRPISPSPS 365
             P     + P + P SP  S
Sbjct: 1304 SPPKGAPTPPAATPPSPKGS 1323



 Score = 32.0 bits (71), Expect = 4.0
 Identities = 22/77 (28%), Positives = 28/77 (36%), Gaps = 4/77 (5%)

Query: 297  APRPGSTAHPPHAIPNSP---PSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRD-RIS 352
            +P P     PP   P SP   P+TP P   P SP   P     S   P + T      + 
Sbjct: 1607 SPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVP 1666

Query: 353  SLPVSRPISPSPSAILE 369
                  P    P+A+ E
Sbjct: 1667 QASKGLPAKKGPTALKE 1683



 Score = 30.8 bits (68), Expect = 8.9
 Identities = 21/73 (28%), Positives = 29/73 (39%), Gaps = 5/73 (6%)

Query: 295  PGAPRPGSTAHPPHAIPNSPPSTPV-----PHSMPPSPSRIPYGGTRSMVVPGNATIPRD 349
            P +P+ G     P   P +P +TP      P + PP  +  P   T   +  G AT P  
Sbjct: 1225 PPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHK 1284

Query: 350  RISSLPVSRPISP 362
               +  V  P SP
Sbjct: 1285 GAPNPAVVTPPSP 1297


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 117/519 (22%), Positives = 170/519 (32%), Gaps = 94/519 (18%)

Query: 819  EAAHTSGQ--PFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHSVALLNPAQNLP 876
            E   +SG+  P  ++ +  D+K+E V  S   V+   SSP+     Q             
Sbjct: 50   EDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQRE----------- 98

Query: 877  HVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKK 936
             VAS        +S    +Q    P  P  G              S+ +R+V+ E     
Sbjct: 99   KVASDTEEADRTSSKKTKTQEISRPNSPSEG-----------EGESSDSRSVNDE----- 142

Query: 937  WEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSP 996
                        G    K +++   +   SIP+ +   +       D+   +  L    P
Sbjct: 143  ------------GSSDPKDIDQDNRSTSPSIPSPQDNESD-----SDSSAQQQMLQAQPP 185

Query: 997  NSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPS 1056
                 L+   G +P P   PP    LP  G T + +          +           P 
Sbjct: 186  ----ALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPV 241

Query: 1057 PQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQT-SRMP 1115
            P T   + PA  P    +P PPP  +                +  L GS+G P   S   
Sbjct: 242  PHTHIQQAPALHPQRPPSPHPPPHPSPHPP------------LQPLTGSAGQPSAPSHAQ 289

Query: 1116 VPMSAKNRPG--------TLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKP-TSPSLPAS 1166
             P+  +  PG         L  PG       P Q  Q       S     P TS  LPAS
Sbjct: 290  PPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349

Query: 1167 KIPALSPSSGKSSSLPSSSGDSSNLPNPPATK----PSIASNPLSPQTGPP---AHSASL 1219
            +    S    +   LP +     ++  PP T     P+  ++   P    P   + +A+L
Sbjct: 350  QSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANL 409

Query: 1220 IPSVSNGSLKFQSLTHTGKGH--HLSFSPQSQ----NGRAPPPLSFSSS-PPSPAS--SV 1270
             P  +   L   S  H    H   L   PQSQ    +   PP L+ S + PP PAS    
Sbjct: 410  PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPT 469

Query: 1271 SLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKETS 1309
             L+Q A        P    +    G     TP T   TS
Sbjct: 470  GLHQVAP------QPPFAQHPFVPGGPPPITPPTCPSTS 502



 Score = 37.4 bits (85), Expect = 0.095
 Identities = 84/386 (21%), Positives = 132/386 (34%), Gaps = 43/386 (11%)

Query: 136 PVEHLSETSADSLEAMSEG-DAPTPFSRGSRTRASLPVVRSTNQTKERSLGVLYLQYGDE 194
           P      TS  + +  S G ++P+  S  S    +  V +S  + KE +   L       
Sbjct: 38  PASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPL------- 90

Query: 195 TKQLRMPNEITSADTIRALFVSAFPQQLT-MKMLESPSVAIYIKDESRNVYYELNDVRNI 253
            K  +   E  ++DT  A   S+   +   +    SPS       +SR+V  E +     
Sbjct: 91  -KSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKD 149

Query: 254 QDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRPGSTAHPPHAIPNS 313
            D+         P+   N +    + D   Q++++ A+   P    P      P + P  
Sbjct: 150 IDQDNRSTSPSIPSPQDNES----DSDSSAQQQMLQAQP--PALQAPTGVTPAPSSAPPG 203

Query: 314 PPSTPVPHSMPPSPSRIPYGGTRSMVVPG-----NATIPRDRISSLPVSRP-ISPSPSAI 367
            P  P P   P + +  P G   +   P       A +P   I   P   P   PSP   
Sbjct: 204 TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP 263

Query: 368 LERRDVKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIASSHGG---------HPLDVP 418
                  P + ++G   A   +   +A P L+ +G     S   G          P  +P
Sbjct: 264 PHPSPHPPLQPLTGS--AGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLP 321

Query: 419 DHIIAYHRTAIRS-ASAYCNPSMQ--AEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASP 475
                       S A+AY + S+Q  A     QS    + +  P + L     K PP +P
Sbjct: 322 PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 381

Query: 476 HRVSDLRMIDMHAHYNAHGPPHTMQP 501
             +  L     H H     PPH   P
Sbjct: 382 --IPQLPAPQAHKH-----PPHLSGP 400



 Score = 37.4 bits (85), Expect = 0.095
 Identities = 41/202 (20%), Positives = 72/202 (35%), Gaps = 11/202 (5%)

Query: 1026 GLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSS 1085
            G T+  + D+  +GR     A  SS D+      ++ K   EE +S    +       +S
Sbjct: 43   GRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVAS 102

Query: 1086 KDEEEEEEEGDKIMAELQGSSGAPQ------TSRMPVPMSAKNRPGTLDKPGKQSKLQDP 1139
              EE +     K   +      +P       +    V     + P  +D+  + +    P
Sbjct: 103  DTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIP 162

Query: 1140 RQY---RQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPA 1196
                    ++ SA++     +P +   P    PA S +   +  LP+     S    PP 
Sbjct: 163  SPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQ 222

Query: 1197 TKPSIASNPLSPQ--TGPPAHS 1216
              P+ +  P  PQ  T P  H+
Sbjct: 223  GSPTASQAPNQPQAPTAPVPHT 244



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 56/269 (20%), Positives = 99/269 (36%), Gaps = 30/269 (11%)

Query: 968  PNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRSYLPGS-- 1025
            P L++ P + PLP   A    +  S++ P         G     P PP  +  ++PG   
Sbjct: 432  PPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPP 491

Query: 1026 --------GLTTTRSGDVVYTGRKENITAKASSEDAG----PSPQTRATKYPAEEPASAW 1073
                      +T  +G         +  A +    AG    P P  +  +   ++     
Sbjct: 492  PITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPE 551

Query: 1074 TPSPPPVTTSSSK---DEEEEEEEGDKIMAEL-QGSSGAPQTSRMPVPMS----AKNRPG 1125
            +P PPP + S      D      +  +    L +G +   +T    +P++    AK R  
Sbjct: 552  SPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREE 611

Query: 1126 TLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSS 1185
             ++K  ++++ Q  R+ R+     +K     +        +   + S   G+ S  P  S
Sbjct: 612  AIEKAKREAE-QKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSD-PQLS 669

Query: 1186 GDSSNLPN--PPATKPSIASNPLSPQTGP 1212
            G     P+  PP T  +IA+ P  P  GP
Sbjct: 670  GPGHMRPSFEPPPT--TIAAVP--PYIGP 694



 Score = 32.0 bits (71), Expect = 4.0
 Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 5/71 (7%)

Query: 295 PGAPRPGSTAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSL 354
           P  P P +  HPPH    SP S  +  ++PP P+  P     +   P     P   +  +
Sbjct: 383 PQLPAPQAHKHPPHLSGPSPFS--MNANLPPPPALKPLSSLSTHHPPSAHPPP---LQLM 437

Query: 355 PVSRPISPSPS 365
           P S+P+  SP+
Sbjct: 438 PQSQPLPSSPA 448



 Score = 31.6 bits (70), Expect = 5.2
 Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 17/83 (20%)

Query: 263 NKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRPGS---TAHPPHAIPNSPPSTPV 319
           +K P H    +P +MN ++             P A +P S   T HPP A P  PP   +
Sbjct: 391 HKHPPHLSGPSPFSMNANL-----------PPPPALKPLSSLSTHHPPSAHP--PPLQLM 437

Query: 320 PHSMP-PSPSRIPYGGTRSMVVP 341
           P S P PS    P G T+S  +P
Sbjct: 438 PQSQPLPSSPAQPPGLTQSQNLP 460


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 117/519 (22%), Positives = 170/519 (32%), Gaps = 94/519 (18%)

Query: 819  EAAHTSGQ--PFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHSVALLNPAQNLP 876
            E   +SG+  P  ++ +  D+K+E V  S   V+   SSP+     Q             
Sbjct: 604  EDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQRE----------- 652

Query: 877  HVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKK 936
             VAS        +S    +Q    P  P  G              S+ +R+V+ E     
Sbjct: 653  KVASDTEEADRTSSKKTKTQEISRPNSPSEG-----------EGESSDSRSVNDE----- 696

Query: 937  WEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSP 996
                        G    K +++   +   SIP+ +   +       D+   +  L    P
Sbjct: 697  ------------GSSDPKDIDQDNRSTSPSIPSPQDNESD-----SDSSAQQQMLQAQPP 739

Query: 997  NSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPS 1056
                 L+   G +P P   PP    LP  G T + +          +           P 
Sbjct: 740  ----ALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPV 795

Query: 1057 PQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQT-SRMP 1115
            P T   + PA  P    +P PPP  +                +  L GS+G P   S   
Sbjct: 796  PHTHIQQAPALHPQRPPSPHPPPHPSPHPP------------LQPLTGSAGQPSAPSHAQ 843

Query: 1116 VPMSAKNRPG--------TLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKP-TSPSLPAS 1166
             P+  +  PG         L  PG       P Q  Q       S     P TS  LPAS
Sbjct: 844  PPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 903

Query: 1167 KIPALSPSSGKSSSLPSSSGDSSNLPNPPATK----PSIASNPLSPQTGPP---AHSASL 1219
            +    S    +   LP +     ++  PP T     P+  ++   P    P   + +A+L
Sbjct: 904  QSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANL 963

Query: 1220 IPSVSNGSLKFQSLTHTGKGH--HLSFSPQSQ----NGRAPPPLSFSSS-PPSPAS--SV 1270
             P  +   L   S  H    H   L   PQSQ    +   PP L+ S + PP PAS    
Sbjct: 964  PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPT 1023

Query: 1271 SLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKETS 1309
             L+Q A        P    +    G     TP T   TS
Sbjct: 1024 GLHQVAP------QPPFAQHPFVPGGPPPITPPTCPSTS 1056



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 58/291 (19%), Positives = 101/291 (34%), Gaps = 31/291 (10%)

Query: 946  HYNGKEFEKLLEEAQANIMK--SIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLE 1003
            H+ G+E   L  + + +  K   +P +E P    P P    PV + +      +S +   
Sbjct: 519  HHGGRENILLCTDCRIHFKKYGELPPIEKP--VDPPPFMFKPVKEEDDGLSGKHSMRTRR 576

Query: 1004 KLG-------GKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPS 1056
              G       G+   P  P          G T+  + D+  +GR     A  SS D+   
Sbjct: 577  SRGSMSTLRSGRKKQPASP---------DGRTSPINEDIRSSGRNSPSAASTSSNDSKAE 627

Query: 1057 PQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQ------ 1110
               ++ K   EE +S    +       +S  EE +     K   +      +P       
Sbjct: 628  TVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGES 687

Query: 1111 TSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQY---RQANGSAKKSGGDFKPTSPSLPASK 1167
            +    V     + P  +D+  + +    P        ++ SA++     +P +   P   
Sbjct: 688  SDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGV 747

Query: 1168 IPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQ--TGPPAHS 1216
             PA S +   +  LP+     S    PP   P+ +  P  PQ  T P  H+
Sbjct: 748  TPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHT 798



 Score = 37.4 bits (85), Expect = 0.095
 Identities = 84/386 (21%), Positives = 132/386 (34%), Gaps = 43/386 (11%)

Query: 136 PVEHLSETSADSLEAMSEG-DAPTPFSRGSRTRASLPVVRSTNQTKERSLGVLYLQYGDE 194
           P      TS  + +  S G ++P+  S  S    +  V +S  + KE +   L       
Sbjct: 592 PASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPL------- 644

Query: 195 TKQLRMPNEITSADTIRALFVSAFPQQLT-MKMLESPSVAIYIKDESRNVYYELNDVRNI 253
            K  +   E  ++DT  A   S+   +   +    SPS       +SR+V  E +     
Sbjct: 645 -KSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKD 703

Query: 254 QDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRPGSTAHPPHAIPNS 313
            D+         P+   N +    + D   Q++++ A+   P    P      P + P  
Sbjct: 704 IDQDNRSTSPSIPSPQDNES----DSDSSAQQQMLQAQP--PALQAPTGVTPAPSSAPPG 757

Query: 314 PPSTPVPHSMPPSPSRIPYGGTRSMVVPG-----NATIPRDRISSLPVSRP-ISPSPSAI 367
            P  P P   P + +  P G   +   P       A +P   I   P   P   PSP   
Sbjct: 758 TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP 817

Query: 368 LERRDVKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIASSHGG---------HPLDVP 418
                  P + ++G   A   +   +A P L+ +G     S   G          P  +P
Sbjct: 818 PHPSPHPPLQPLTGS--AGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLP 875

Query: 419 DHIIAYHRTAIRS-ASAYCNPSMQ--AEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASP 475
                       S A+AY + S+Q  A     QS    + +  P + L     K PP +P
Sbjct: 876 PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 935

Query: 476 HRVSDLRMIDMHAHYNAHGPPHTMQP 501
             +  L     H H     PPH   P
Sbjct: 936 --IPQLPAPQAHKH-----PPHLSGP 954



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 56/269 (20%), Positives = 99/269 (36%), Gaps = 30/269 (11%)

Query: 968  PNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRSYLPGS-- 1025
            P L++ P + PLP   A    +  S++ P         G     P PP  +  ++PG   
Sbjct: 986  PPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPP 1045

Query: 1026 --------GLTTTRSGDVVYTGRKENITAKASSEDAG----PSPQTRATKYPAEEPASAW 1073
                      +T  +G         +  A +    AG    P P  +  +   ++     
Sbjct: 1046 PITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPE 1105

Query: 1074 TPSPPPVTTSSSK---DEEEEEEEGDKIMAEL-QGSSGAPQTSRMPVPMS----AKNRPG 1125
            +P PPP + S      D      +  +    L +G +   +T    +P++    AK R  
Sbjct: 1106 SPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREE 1165

Query: 1126 TLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSS 1185
             ++K  ++++ Q  R+ R+     +K     +        +   + S   G+ S  P  S
Sbjct: 1166 AIEKAKREAE-QKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSD-PQLS 1223

Query: 1186 GDSSNLPN--PPATKPSIASNPLSPQTGP 1212
            G     P+  PP T  +IA+ P  P  GP
Sbjct: 1224 GPGHMRPSFEPPPT--TIAAVP--PYIGP 1248



 Score = 32.0 bits (71), Expect = 4.0
 Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 5/71 (7%)

Query: 295  PGAPRPGSTAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSL 354
            P  P P +  HPPH    SP S  +  ++PP P+  P     +   P     P   +  +
Sbjct: 937  PQLPAPQAHKHPPHLSGPSPFS--MNANLPPPPALKPLSSLSTHHPPSAHPPP---LQLM 991

Query: 355  PVSRPISPSPS 365
            P S+P+  SP+
Sbjct: 992  PQSQPLPSSPA 1002



 Score = 31.6 bits (70), Expect = 5.2
 Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 17/83 (20%)

Query: 263  NKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRPGS---TAHPPHAIPNSPPSTPV 319
            +K P H    +P +MN ++             P A +P S   T HPP A P  PP   +
Sbjct: 945  HKHPPHLSGPSPFSMNANL-----------PPPPALKPLSSLSTHHPPSAHP--PPLQLM 991

Query: 320  PHSMP-PSPSRIPYGGTRSMVVP 341
            P S P PS    P G T+S  +P
Sbjct: 992  PQSQPLPSSPAQPPGLTQSQNLP 1014


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 117/519 (22%), Positives = 170/519 (32%), Gaps = 94/519 (18%)

Query: 819  EAAHTSGQ--PFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHSVALLNPAQNLP 876
            E   +SG+  P  ++ +  D+K+E V  S   V+   SSP+     Q             
Sbjct: 604  EDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQRE----------- 652

Query: 877  HVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKK 936
             VAS        +S    +Q    P  P  G              S+ +R+V+ E     
Sbjct: 653  KVASDTEEADRTSSKKTKTQEISRPNSPSEG-----------EGESSDSRSVNDE----- 696

Query: 937  WEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSP 996
                        G    K +++   +   SIP+ +   +       D+   +  L    P
Sbjct: 697  ------------GSSDPKDIDQDNRSTSPSIPSPQDNESD-----SDSSAQQQMLQAQPP 739

Query: 997  NSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPS 1056
                 L+   G +P P   PP    LP  G T + +          +           P 
Sbjct: 740  ----ALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPV 795

Query: 1057 PQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQT-SRMP 1115
            P T   + PA  P    +P PPP  +                +  L GS+G P   S   
Sbjct: 796  PHTHIQQAPALHPQRPPSPHPPPHPSPHPP------------LQPLTGSAGQPSAPSHAQ 843

Query: 1116 VPMSAKNRPG--------TLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKP-TSPSLPAS 1166
             P+  +  PG         L  PG       P Q  Q       S     P TS  LPAS
Sbjct: 844  PPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 903

Query: 1167 KIPALSPSSGKSSSLPSSSGDSSNLPNPPATK----PSIASNPLSPQTGPP---AHSASL 1219
            +    S    +   LP +     ++  PP T     P+  ++   P    P   + +A+L
Sbjct: 904  QSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANL 963

Query: 1220 IPSVSNGSLKFQSLTHTGKGH--HLSFSPQSQ----NGRAPPPLSFSSS-PPSPAS--SV 1270
             P  +   L   S  H    H   L   PQSQ    +   PP L+ S + PP PAS    
Sbjct: 964  PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPT 1023

Query: 1271 SLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKETS 1309
             L+Q A        P    +    G     TP T   TS
Sbjct: 1024 GLHQVAP------QPPFAQHPFVPGGPPPITPPTCPSTS 1056



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 58/291 (19%), Positives = 101/291 (34%), Gaps = 31/291 (10%)

Query: 946  HYNGKEFEKLLEEAQANIMK--SIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLE 1003
            H+ G+E   L  + + +  K   +P +E P    P P    PV + +      +S +   
Sbjct: 519  HHGGRENILLCTDCRIHFKKYGELPPIEKP--VDPPPFMFKPVKEEDDGLSGKHSMRTRR 576

Query: 1004 KLG-------GKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPS 1056
              G       G+   P  P          G T+  + D+  +GR     A  SS D+   
Sbjct: 577  SRGSMSTLRSGRKKQPASP---------DGRTSPINEDIRSSGRNSPSAASTSSNDSKAE 627

Query: 1057 PQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQ------ 1110
               ++ K   EE +S    +       +S  EE +     K   +      +P       
Sbjct: 628  TVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGES 687

Query: 1111 TSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQY---RQANGSAKKSGGDFKPTSPSLPASK 1167
            +    V     + P  +D+  + +    P        ++ SA++     +P +   P   
Sbjct: 688  SDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGV 747

Query: 1168 IPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQ--TGPPAHS 1216
             PA S +   +  LP+     S    PP   P+ +  P  PQ  T P  H+
Sbjct: 748  TPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHT 798



 Score = 37.4 bits (85), Expect = 0.095
 Identities = 84/386 (21%), Positives = 132/386 (34%), Gaps = 43/386 (11%)

Query: 136 PVEHLSETSADSLEAMSEG-DAPTPFSRGSRTRASLPVVRSTNQTKERSLGVLYLQYGDE 194
           P      TS  + +  S G ++P+  S  S    +  V +S  + KE +   L       
Sbjct: 592 PASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPL------- 644

Query: 195 TKQLRMPNEITSADTIRALFVSAFPQQLT-MKMLESPSVAIYIKDESRNVYYELNDVRNI 253
            K  +   E  ++DT  A   S+   +   +    SPS       +SR+V  E +     
Sbjct: 645 -KSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKD 703

Query: 254 QDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRPGSTAHPPHAIPNS 313
            D+         P+   N +    + D   Q++++ A+   P    P      P + P  
Sbjct: 704 IDQDNRSTSPSIPSPQDNES----DSDSSAQQQMLQAQP--PALQAPTGVTPAPSSAPPG 757

Query: 314 PPSTPVPHSMPPSPSRIPYGGTRSMVVPG-----NATIPRDRISSLPVSRP-ISPSPSAI 367
            P  P P   P + +  P G   +   P       A +P   I   P   P   PSP   
Sbjct: 758 TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP 817

Query: 368 LERRDVKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIASSHGG---------HPLDVP 418
                  P + ++G   A   +   +A P L+ +G     S   G          P  +P
Sbjct: 818 PHPSPHPPLQPLTGS--AGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLP 875

Query: 419 DHIIAYHRTAIRS-ASAYCNPSMQ--AEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASP 475
                       S A+AY + S+Q  A     QS    + +  P + L     K PP +P
Sbjct: 876 PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 935

Query: 476 HRVSDLRMIDMHAHYNAHGPPHTMQP 501
             +  L     H H     PPH   P
Sbjct: 936 --IPQLPAPQAHKH-----PPHLSGP 954



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 56/269 (20%), Positives = 99/269 (36%), Gaps = 30/269 (11%)

Query: 968  PNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRSYLPGS-- 1025
            P L++ P + PLP   A    +  S++ P         G     P PP  +  ++PG   
Sbjct: 986  PPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPP 1045

Query: 1026 --------GLTTTRSGDVVYTGRKENITAKASSEDAG----PSPQTRATKYPAEEPASAW 1073
                      +T  +G         +  A +    AG    P P  +  +   ++     
Sbjct: 1046 PITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPE 1105

Query: 1074 TPSPPPVTTSSSK---DEEEEEEEGDKIMAEL-QGSSGAPQTSRMPVPMS----AKNRPG 1125
            +P PPP + S      D      +  +    L +G +   +T    +P++    AK R  
Sbjct: 1106 SPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREE 1165

Query: 1126 TLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSS 1185
             ++K  ++++ Q  R+ R+     +K     +        +   + S   G+ S  P  S
Sbjct: 1166 AIEKAKREAE-QKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSD-PQLS 1223

Query: 1186 GDSSNLPN--PPATKPSIASNPLSPQTGP 1212
            G     P+  PP T  +IA+ P  P  GP
Sbjct: 1224 GPGHMRPSFEPPPT--TIAAVP--PYIGP 1248



 Score = 32.0 bits (71), Expect = 4.0
 Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 5/71 (7%)

Query: 295  PGAPRPGSTAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSL 354
            P  P P +  HPPH    SP S  +  ++PP P+  P     +   P     P   +  +
Sbjct: 937  PQLPAPQAHKHPPHLSGPSPFS--MNANLPPPPALKPLSSLSTHHPPSAHPPP---LQLM 991

Query: 355  PVSRPISPSPS 365
            P S+P+  SP+
Sbjct: 992  PQSQPLPSSPA 1002



 Score = 31.6 bits (70), Expect = 5.2
 Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 17/83 (20%)

Query: 263  NKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRPGS---TAHPPHAIPNSPPSTPV 319
            +K P H    +P +MN ++             P A +P S   T HPP A P  PP   +
Sbjct: 945  HKHPPHLSGPSPFSMNANL-----------PPPPALKPLSSLSTHHPPSAHP--PPLQLM 991

Query: 320  PHSMP-PSPSRIPYGGTRSMVVP 341
            P S P PS    P G T+S  +P
Sbjct: 992  PQSQPLPSSPAQPPGLTQSQNLP 1014


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 109/477 (22%), Positives = 150/477 (31%), Gaps = 94/477 (19%)

Query: 850  RHAQSSPVVIQPSQHSVALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQ------SPQI 903
            RH  SS      SQ S  +++    L     S   P+ +T++  +   PQ      SP  
Sbjct: 407  RHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSG 466

Query: 904  PMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQNLD-HYNGKEF-EKLLEEAQA 961
                 A  +L I     +S   R+VS+ K ++     R+    H  G    +  L     
Sbjct: 467  GSTAEASDTLSIRSSGQLSG--RSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPK 524

Query: 962  NIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRSY 1021
               K  P L  PP TG                    SE       G    P PP P  S+
Sbjct: 525  PERKQQPQLPRPPTTG-------------------GSE-------GAGAAPCPPNPANSW 558

Query: 1022 LPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVT 1081
            +PG     +R        R  + ++  SS+   P+   +    P   P  A  P P  VT
Sbjct: 559  VPGLSPGGSRRPPRS-PERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVT 617

Query: 1082 T----------------SSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPG 1125
            +                SSS D    +  G +I+  L      P   ++P P S      
Sbjct: 618  SLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKP 677

Query: 1126 TLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPAL--SPSSGKSSSLPS 1183
                P        P     A      S  D  P SP  P + +  L  SP   K  S P 
Sbjct: 678  RSPNPAA------PALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPP 731

Query: 1184 SSGDSSNLPNPPATKPSI----------ASNPLS----PQTGPPAHS------------- 1216
            S   S + P PP  KP +          A  PL     P   PPA               
Sbjct: 732  SPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPE 791

Query: 1217 ------ASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPA 1267
                  AS  P+  +GS +  S          +   Q      PPP   + +P S A
Sbjct: 792  EAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSA 848



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 76/297 (25%), Positives = 107/297 (36%), Gaps = 52/297 (17%)

Query: 956  LEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNS----EQDLEKLGGKSPP 1011
            L+E+        P    PP+  P P    P  K E+  ++P++    E+ L+      PP
Sbjct: 717  LQESPVISKDQSPPPSPPPSYHPPP---PPTKKPEVVVEAPSASETAEEPLQDPNWPPPP 773

Query: 1012 PPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPAS 1071
            PP P  +   +              +   +E   + AS E AGPS        PA   +S
Sbjct: 774  PPAPEEQDLSMAD------------FPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSS 821

Query: 1072 A--------WTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSS--GAPQTSRMPVPMSAK 1121
            A         +P PPP   + +               E  G S  G P    +  P+   
Sbjct: 822  ATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVT- 880

Query: 1122 NRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSG----- 1176
              P  L    +  +L+       A   A       KP   +L     P  +PSSG     
Sbjct: 881  --PSLL----QMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAV 934

Query: 1177 --KSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQ 1231
              K+ SL +S G SS  PN P       + P  PQ+  PA +AS I   S GS K Q
Sbjct: 935  RLKACSLAASEGLSSAQPNGPP-----EAEPRPPQS--PASTASFI--FSKGSRKLQ 982



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 82/346 (23%), Positives = 126/346 (36%), Gaps = 58/346 (16%)

Query: 963  IMKSIPNLEMPPATGPLPRGDAPV---DKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRR 1019
            + K IP+  +PP    +  G   +    +  L   SP S + L +    S P P     R
Sbjct: 351  LSKLIPHAVLPPTVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQP-----R 405

Query: 1020 SYLPGSGLTT---TRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPS 1076
            S  P S   T   ++S D + +     +++K  SE    S     +  P  +  S    S
Sbjct: 406  SRHPSSSSDTWSHSQSSDTIVSDGS-TLSSKGGSEGQPESSTASNSVVPPPQGGSG-RGS 463

Query: 1077 PPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRP----------GT 1126
            P   +T+ + D       G     +L G S + +  + P P   +             G 
Sbjct: 464  PSGGSTAEASDTLSIRSSG-----QLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGP 518

Query: 1127 LDKPGKQSKLQDPRQYRQ-ANGSAKKSGGDFKPTSPSL--------------PASKIPAL 1171
            L  P K  + Q P+  R    G ++ +G    P +P+               P S    L
Sbjct: 519  LGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTL 578

Query: 1172 SPSSGKSSSLPSSSGDSSNLPNPPAT-------KPSIASNPLSPQTGPPAHSASLIPSVS 1224
            SPSSG SS   + +     L  PPA+       KP   ++  SP     +   SL  S S
Sbjct: 579  SPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSS 638

Query: 1225 NGSLKFQS----LTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSP 1266
            + +   +S    LT  G    +   P+     +PPP    S P SP
Sbjct: 639  DPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPP----SKPRSP 680


>gi|18959210 WIRE protein [Homo sapiens]
          Length = 440

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 67/298 (22%), Positives = 99/298 (33%), Gaps = 60/298 (20%)

Query: 996  PNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGP 1055
            PN+          S PPPPPP RR+  P + L    S    Y   K             P
Sbjct: 162  PNTTSSTGMKHSSSAPPPPPPGRRANAPPTPLPMHSSKAPAYNREK-------------P 208

Query: 1056 SPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMP 1115
             P T   +     P     P+PPPV    S                +   +G    S  P
Sbjct: 209  LPPTPGQRL---HPGREGPPAPPPVKPPPSP---------------VNIRTGPSGQSLAP 250

Query: 1116 VPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSS 1175
             P   +  PG  + P   +    P   ++ N   +K+ G  +  +P  P S  P+L    
Sbjct: 251  PPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSL---- 306

Query: 1176 GKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTH 1235
                         SN P PPA  P   S   +P   PP         + NG+   +    
Sbjct: 307  ------------LSNRPPPPARDP--PSRGAAPPPPPPV--------IRNGA---RDAPP 341

Query: 1236 TGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQ 1293
                + +  S     G+ PPP S + + P P     L  G + + T     L  ++++
Sbjct: 342  PPPPYRMHGSEPPSRGKPPPPPSRTPAGPPPPPPPPLRNGHRDSITTVRSFLDDFESK 399



 Score = 33.9 bits (76), Expect = 1.1
 Identities = 73/275 (26%), Positives = 103/275 (37%), Gaps = 39/275 (14%)

Query: 1010 PPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEP 1069
            PPPPPPPP     P      T    +    R E     A  +D      T+  K      
Sbjct: 4    PPPPPPPPGPPPPPTFHQANTEQPKL---SRDEQRGRGALLQDICKG--TKLKKVTNIND 58

Query: 1070 ASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPV-PMSAKNRPGTL- 1127
             SA      P+              G    A LQ   G  Q   + + P+ AK+    L 
Sbjct: 59   RSA------PILEKPKGSSGGYGSGG----AALQPKGGLFQGGVLKLRPVGAKDGSENLA 108

Query: 1128 DKPGKQ---SKLQDPRQ-YRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPS 1183
             KP  Q   S+   PR     A+G  +      + + P LP  + P+L   S  +++  +
Sbjct: 109  GKPALQIPSSRAAAPRPPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSST 168

Query: 1184 SSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLS 1243
                SS+ P PP   P   +N  +P T  P HS S  P+ +    + + L  T  G  L 
Sbjct: 169  GMKHSSSAPPPP--PPGRRAN--APPTPLPMHS-SKAPAYN----REKPLPPT-PGQRL- 217

Query: 1244 FSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKG 1278
              P  +   APPP+     PPSP   V++  G  G
Sbjct: 218  -HPGREGPPAPPPV---KPPPSP---VNIRTGPSG 245


>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
            sapiens]
          Length = 1188

 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 81/324 (25%), Positives = 120/324 (37%), Gaps = 64/324 (19%)

Query: 1009 SPPPPPPPPRRSYLPGS-----------GLTTTRSGDVVYTGRKENIT--------AKAS 1049
            +PPPPP P      P S           G  T    DV   GR+   T        A+  
Sbjct: 225  APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPK 284

Query: 1050 SEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEE----EEGDKIMAELQGS 1105
                GP+P+   T      P S   P P PV TSS   +E +E    EEG         +
Sbjct: 285  GSALGPNPEPHLTF-----PRSFKVPPPTPVRTSSIPVQEAQEAPRKEEG--------AT 331

Query: 1106 SGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYR----------QANGSAKKSGGD 1155
              AP  SR+P+P S   RP +   P +  +   P + +          Q+   A +  G 
Sbjct: 332  KKAP--SRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGT 389

Query: 1156 FKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPA--TKPSIASNP-LSPQTGP 1212
              P +P LP    P   P+     + P     +    +PPA  TK   +S+P L P+  P
Sbjct: 390  -PPPAPPLPPPAPPLPPPAPPLPPAAPPLP-CAQKAAHPPAGFTKTPKSSSPALKPKPNP 447

Query: 1213 PA--HSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSV 1270
            P+  ++AS  P       + + L +    +      + +         F S  P P  + 
Sbjct: 448  PSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDR---------FLSHRPGPTVAP 498

Query: 1271 SLNQGAKGTRTIHTPSLTSYKAQN 1294
               +G KG R     +L S  A++
Sbjct: 499  QSKEGKKGPRLPEKETLLSLPAKD 522



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 85/376 (22%), Positives = 133/376 (35%), Gaps = 49/376 (13%)

Query: 968  PNLEMPPATGPLP-RGDAPVDKVELSEDSP------NSEQDLEKLGGKSPPPPPPPPRRS 1020
            P+  + PA+   P R   P    EL   +P       S+   ++  G  PP PP PP   
Sbjct: 342  PSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAP 401

Query: 1021 YLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYP-AEEPASAWTPSPP- 1078
             LP        +   +   +K               P    TK P +  PA    P+PP 
Sbjct: 402  PLPPPAPPLPPAAPPLPCAQK------------AAHPPAGFTKTPKSSSPALKPKPNPPS 449

Query: 1079 PVTTSSS-----KDEEEEEEEGDKIMAELQGS-------SGAPQTSRMPVPMSAKNRPGT 1126
            P  T+SS     +D  + E+  +++ A L GS       S  P  +  P     K  P  
Sbjct: 450  PENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRL 509

Query: 1127 LDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALS--PSSGKSSSLPSS 1184
               P K++ L  P +        K  GG     + + P+  +P++   P    + S+   
Sbjct: 510  ---PEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQI 566

Query: 1185 SGDSSNLPNPPA---TKPSIASNPLSP--QTGPPAHSASLIPSVSNGSLKFQSLTHTGKG 1239
              +     +  A    KPSI S P  P  + G    + +    +S    K      T   
Sbjct: 567  RNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLL 626

Query: 1240 HHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTP------SLTSYKAQ 1293
               S  P++  G A PP +       P +++      K T    TP        T  KA 
Sbjct: 627  PTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKAT 686

Query: 1294 NGSSSKATPSTAKETS 1309
            +G +  +T +T   T+
Sbjct: 687  SGPAIASTATTLPTTT 702



 Score = 38.1 bits (87), Expect = 0.056
 Identities = 39/140 (27%), Positives = 55/140 (39%), Gaps = 16/140 (11%)

Query: 1169 PALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSL 1228
            P   P+ G    +    G S  LP+PP+T P     PL  +  PP   A   P V     
Sbjct: 142  PPPGPAPGPPQDISEPPGGSP-LPSPPSTAPP--PPPLLLEPPPPPSMAPPPPPVLEALS 198

Query: 1229 KFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSP----PSPASSVSLNQGAKGTRTIHT 1284
               +L+         F P +      PPL+F + P    P+PA     +    GTR    
Sbjct: 199  PPHTLSSPSIPTPPDFIPPA------PPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPP 252

Query: 1285 PSLTSYK---AQNGSSSKAT 1301
              +T +K   A NG  ++AT
Sbjct: 253  GGVTKWKSDVALNGRQAEAT 272



 Score = 37.7 bits (86), Expect = 0.073
 Identities = 75/319 (23%), Positives = 107/319 (33%), Gaps = 56/319 (17%)

Query: 995  SPNSEQDLEKLGGKSP--------PPPPP------------PPRRSYLPGSGLTTTRSGD 1034
            +P   QD+ +  G SP        PPPPP            PP    L       T S  
Sbjct: 147  APGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSP 206

Query: 1035 VVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPS----PPPVTTS------- 1083
             + T       A   +  A P P   A   PA  PAS  T      PP   T        
Sbjct: 207  SIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPA--PASPHTVGTRLFPPGGVTKWKSDVAL 264

Query: 1084 SSKDEEEEEEEGDKIMAELQGSSGAPQTS-RMPVPMSAKNRPGTLDKPGKQSKLQDPRQY 1142
            + +  E       +  AE +GS+  P     +  P S K  P T  +       +     
Sbjct: 265  NGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAP 324

Query: 1143 RQANGSAKKSGGDFKPTSPSL---PASKI--------------PALSPSSGKSSSLPSSS 1185
            R+  G+ KK+     P  PS    PAS++               A +P+S +     S +
Sbjct: 325  RKEEGATKKAPSRL-PLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQA 383

Query: 1186 GDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFS 1245
             + +  P PPA      + PL P   P   +A  +P     +      T T K    +  
Sbjct: 384  DERAGTP-PPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALK 442

Query: 1246 PQSQNGRAPPPLSFSSSPP 1264
            P+      P P + +SS P
Sbjct: 443  PKP---NPPSPENTASSAP 458



 Score = 32.3 bits (72), Expect = 3.1
 Identities = 32/117 (27%), Positives = 49/117 (41%), Gaps = 12/117 (10%)

Query: 296 GAPRPGSTAHPPHAIPNSPPSTPVPHSMPPSP-----SRIPYGGTRSMVVPGNATIPRDR 350
           G P P     PP A P  PP+ P+P + PP P     +  P G T++      A  P+  
Sbjct: 388 GTPPPAPPLPPP-APPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPN 446

Query: 351 ISSLPVSRPISPSPSAILERRDVKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIA 407
             S     P + + SA ++ RD    E +  + +A Y       D +L H    ++A
Sbjct: 447 PPS-----PENTASSAPVDWRDPSQMEKLRNE-LAAYLCGSRREDRFLSHRPGPTVA 497


>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
            sapiens]
          Length = 1188

 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 81/324 (25%), Positives = 120/324 (37%), Gaps = 64/324 (19%)

Query: 1009 SPPPPPPPPRRSYLPGS-----------GLTTTRSGDVVYTGRKENIT--------AKAS 1049
            +PPPPP P      P S           G  T    DV   GR+   T        A+  
Sbjct: 225  APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPK 284

Query: 1050 SEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEE----EEGDKIMAELQGS 1105
                GP+P+   T      P S   P P PV TSS   +E +E    EEG         +
Sbjct: 285  GSALGPNPEPHLTF-----PRSFKVPPPTPVRTSSIPVQEAQEAPRKEEG--------AT 331

Query: 1106 SGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYR----------QANGSAKKSGGD 1155
              AP  SR+P+P S   RP +   P +  +   P + +          Q+   A +  G 
Sbjct: 332  KKAP--SRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGT 389

Query: 1156 FKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPA--TKPSIASNP-LSPQTGP 1212
              P +P LP    P   P+     + P     +    +PPA  TK   +S+P L P+  P
Sbjct: 390  -PPPAPPLPPPAPPLPPPAPPLPPAAPPLP-CAQKAAHPPAGFTKTPKSSSPALKPKPNP 447

Query: 1213 PA--HSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSV 1270
            P+  ++AS  P       + + L +    +      + +         F S  P P  + 
Sbjct: 448  PSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDR---------FLSHRPGPTVAP 498

Query: 1271 SLNQGAKGTRTIHTPSLTSYKAQN 1294
               +G KG R     +L S  A++
Sbjct: 499  QSKEGKKGPRLPEKETLLSLPAKD 522



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 85/376 (22%), Positives = 133/376 (35%), Gaps = 49/376 (13%)

Query: 968  PNLEMPPATGPLP-RGDAPVDKVELSEDSP------NSEQDLEKLGGKSPPPPPPPPRRS 1020
            P+  + PA+   P R   P    EL   +P       S+   ++  G  PP PP PP   
Sbjct: 342  PSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAP 401

Query: 1021 YLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYP-AEEPASAWTPSPP- 1078
             LP        +   +   +K               P    TK P +  PA    P+PP 
Sbjct: 402  PLPPPAPPLPPAAPPLPCAQK------------AAHPPAGFTKTPKSSSPALKPKPNPPS 449

Query: 1079 PVTTSSS-----KDEEEEEEEGDKIMAELQGS-------SGAPQTSRMPVPMSAKNRPGT 1126
            P  T+SS     +D  + E+  +++ A L GS       S  P  +  P     K  P  
Sbjct: 450  PENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRL 509

Query: 1127 LDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALS--PSSGKSSSLPSS 1184
               P K++ L  P +        K  GG     + + P+  +P++   P    + S+   
Sbjct: 510  ---PEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQI 566

Query: 1185 SGDSSNLPNPPA---TKPSIASNPLSP--QTGPPAHSASLIPSVSNGSLKFQSLTHTGKG 1239
              +     +  A    KPSI S P  P  + G    + +    +S    K      T   
Sbjct: 567  RNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLL 626

Query: 1240 HHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTP------SLTSYKAQ 1293
               S  P++  G A PP +       P +++      K T    TP        T  KA 
Sbjct: 627  PTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKAT 686

Query: 1294 NGSSSKATPSTAKETS 1309
            +G +  +T +T   T+
Sbjct: 687  SGPAIASTATTLPTTT 702



 Score = 38.1 bits (87), Expect = 0.056
 Identities = 39/140 (27%), Positives = 55/140 (39%), Gaps = 16/140 (11%)

Query: 1169 PALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSL 1228
            P   P+ G    +    G S  LP+PP+T P     PL  +  PP   A   P V     
Sbjct: 142  PPPGPAPGPPQDISEPPGGSP-LPSPPSTAPP--PPPLLLEPPPPPSMAPPPPPVLEALS 198

Query: 1229 KFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSP----PSPASSVSLNQGAKGTRTIHT 1284
               +L+         F P +      PPL+F + P    P+PA     +    GTR    
Sbjct: 199  PPHTLSSPSIPTPPDFIPPA------PPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPP 252

Query: 1285 PSLTSYK---AQNGSSSKAT 1301
              +T +K   A NG  ++AT
Sbjct: 253  GGVTKWKSDVALNGRQAEAT 272



 Score = 37.7 bits (86), Expect = 0.073
 Identities = 75/319 (23%), Positives = 107/319 (33%), Gaps = 56/319 (17%)

Query: 995  SPNSEQDLEKLGGKSP--------PPPPP------------PPRRSYLPGSGLTTTRSGD 1034
            +P   QD+ +  G SP        PPPPP            PP    L       T S  
Sbjct: 147  APGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSP 206

Query: 1035 VVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPS----PPPVTTS------- 1083
             + T       A   +  A P P   A   PA  PAS  T      PP   T        
Sbjct: 207  SIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPA--PASPHTVGTRLFPPGGVTKWKSDVAL 264

Query: 1084 SSKDEEEEEEEGDKIMAELQGSSGAPQTS-RMPVPMSAKNRPGTLDKPGKQSKLQDPRQY 1142
            + +  E       +  AE +GS+  P     +  P S K  P T  +       +     
Sbjct: 265  NGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAP 324

Query: 1143 RQANGSAKKSGGDFKPTSPSL---PASKI--------------PALSPSSGKSSSLPSSS 1185
            R+  G+ KK+     P  PS    PAS++               A +P+S +     S +
Sbjct: 325  RKEEGATKKAPSRL-PLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQA 383

Query: 1186 GDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFS 1245
             + +  P PPA      + PL P   P   +A  +P     +      T T K    +  
Sbjct: 384  DERAGTP-PPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALK 442

Query: 1246 PQSQNGRAPPPLSFSSSPP 1264
            P+      P P + +SS P
Sbjct: 443  PKP---NPPSPENTASSAP 458



 Score = 32.3 bits (72), Expect = 3.1
 Identities = 32/117 (27%), Positives = 49/117 (41%), Gaps = 12/117 (10%)

Query: 296 GAPRPGSTAHPPHAIPNSPPSTPVPHSMPPSP-----SRIPYGGTRSMVVPGNATIPRDR 350
           G P P     PP A P  PP+ P+P + PP P     +  P G T++      A  P+  
Sbjct: 388 GTPPPAPPLPPP-APPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPN 446

Query: 351 ISSLPVSRPISPSPSAILERRDVKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIA 407
             S     P + + SA ++ RD    E +  + +A Y       D +L H    ++A
Sbjct: 447 PPS-----PENTASSAPVDWRDPSQMEKLRNE-LAAYLCGSRREDRFLSHRPGPTVA 497


>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sapiens]
          Length = 1188

 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 81/324 (25%), Positives = 120/324 (37%), Gaps = 64/324 (19%)

Query: 1009 SPPPPPPPPRRSYLPGS-----------GLTTTRSGDVVYTGRKENIT--------AKAS 1049
            +PPPPP P      P S           G  T    DV   GR+   T        A+  
Sbjct: 225  APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPK 284

Query: 1050 SEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEE----EEGDKIMAELQGS 1105
                GP+P+   T      P S   P P PV TSS   +E +E    EEG         +
Sbjct: 285  GSALGPNPEPHLTF-----PRSFKVPPPTPVRTSSIPVQEAQEAPRKEEG--------AT 331

Query: 1106 SGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYR----------QANGSAKKSGGD 1155
              AP  SR+P+P S   RP +   P +  +   P + +          Q+   A +  G 
Sbjct: 332  KKAP--SRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGT 389

Query: 1156 FKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPA--TKPSIASNP-LSPQTGP 1212
              P +P LP    P   P+     + P     +    +PPA  TK   +S+P L P+  P
Sbjct: 390  -PPPAPPLPPPAPPLPPPAPPLPPAAPPLP-CAQKAAHPPAGFTKTPKSSSPALKPKPNP 447

Query: 1213 PA--HSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSV 1270
            P+  ++AS  P       + + L +    +      + +         F S  P P  + 
Sbjct: 448  PSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDR---------FLSHRPGPTVAP 498

Query: 1271 SLNQGAKGTRTIHTPSLTSYKAQN 1294
               +G KG R     +L S  A++
Sbjct: 499  QSKEGKKGPRLPEKETLLSLPAKD 522



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 85/376 (22%), Positives = 133/376 (35%), Gaps = 49/376 (13%)

Query: 968  PNLEMPPATGPLP-RGDAPVDKVELSEDSP------NSEQDLEKLGGKSPPPPPPPPRRS 1020
            P+  + PA+   P R   P    EL   +P       S+   ++  G  PP PP PP   
Sbjct: 342  PSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAP 401

Query: 1021 YLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYP-AEEPASAWTPSPP- 1078
             LP        +   +   +K               P    TK P +  PA    P+PP 
Sbjct: 402  PLPPPAPPLPPAAPPLPCAQK------------AAHPPAGFTKTPKSSSPALKPKPNPPS 449

Query: 1079 PVTTSSS-----KDEEEEEEEGDKIMAELQGS-------SGAPQTSRMPVPMSAKNRPGT 1126
            P  T+SS     +D  + E+  +++ A L GS       S  P  +  P     K  P  
Sbjct: 450  PENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRL 509

Query: 1127 LDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALS--PSSGKSSSLPSS 1184
               P K++ L  P +        K  GG     + + P+  +P++   P    + S+   
Sbjct: 510  ---PEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQI 566

Query: 1185 SGDSSNLPNPPA---TKPSIASNPLSP--QTGPPAHSASLIPSVSNGSLKFQSLTHTGKG 1239
              +     +  A    KPSI S P  P  + G    + +    +S    K      T   
Sbjct: 567  RNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLL 626

Query: 1240 HHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTP------SLTSYKAQ 1293
               S  P++  G A PP +       P +++      K T    TP        T  KA 
Sbjct: 627  PTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKAT 686

Query: 1294 NGSSSKATPSTAKETS 1309
            +G +  +T +T   T+
Sbjct: 687  SGPAIASTATTLPTTT 702



 Score = 38.1 bits (87), Expect = 0.056
 Identities = 39/140 (27%), Positives = 55/140 (39%), Gaps = 16/140 (11%)

Query: 1169 PALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSL 1228
            P   P+ G    +    G S  LP+PP+T P     PL  +  PP   A   P V     
Sbjct: 142  PPPGPAPGPPQDISEPPGGSP-LPSPPSTAPP--PPPLLLEPPPPPSMAPPPPPVLEALS 198

Query: 1229 KFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSP----PSPASSVSLNQGAKGTRTIHT 1284
               +L+         F P +      PPL+F + P    P+PA     +    GTR    
Sbjct: 199  PPHTLSSPSIPTPPDFIPPA------PPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPP 252

Query: 1285 PSLTSYK---AQNGSSSKAT 1301
              +T +K   A NG  ++AT
Sbjct: 253  GGVTKWKSDVALNGRQAEAT 272



 Score = 37.7 bits (86), Expect = 0.073
 Identities = 75/319 (23%), Positives = 107/319 (33%), Gaps = 56/319 (17%)

Query: 995  SPNSEQDLEKLGGKSP--------PPPPP------------PPRRSYLPGSGLTTTRSGD 1034
            +P   QD+ +  G SP        PPPPP            PP    L       T S  
Sbjct: 147  APGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSP 206

Query: 1035 VVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPS----PPPVTTS------- 1083
             + T       A   +  A P P   A   PA  PAS  T      PP   T        
Sbjct: 207  SIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPA--PASPHTVGTRLFPPGGVTKWKSDVAL 264

Query: 1084 SSKDEEEEEEEGDKIMAELQGSSGAPQTS-RMPVPMSAKNRPGTLDKPGKQSKLQDPRQY 1142
            + +  E       +  AE +GS+  P     +  P S K  P T  +       +     
Sbjct: 265  NGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAP 324

Query: 1143 RQANGSAKKSGGDFKPTSPSL---PASKI--------------PALSPSSGKSSSLPSSS 1185
            R+  G+ KK+     P  PS    PAS++               A +P+S +     S +
Sbjct: 325  RKEEGATKKAPSRL-PLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQA 383

Query: 1186 GDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFS 1245
             + +  P PPA      + PL P   P   +A  +P     +      T T K    +  
Sbjct: 384  DERAGTP-PPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALK 442

Query: 1246 PQSQNGRAPPPLSFSSSPP 1264
            P+      P P + +SS P
Sbjct: 443  PKP---NPPSPENTASSAP 458



 Score = 32.3 bits (72), Expect = 3.1
 Identities = 32/117 (27%), Positives = 49/117 (41%), Gaps = 12/117 (10%)

Query: 296 GAPRPGSTAHPPHAIPNSPPSTPVPHSMPPSP-----SRIPYGGTRSMVVPGNATIPRDR 350
           G P P     PP A P  PP+ P+P + PP P     +  P G T++      A  P+  
Sbjct: 388 GTPPPAPPLPPP-APPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPN 446

Query: 351 ISSLPVSRPISPSPSAILERRDVKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIA 407
             S     P + + SA ++ RD    E +  + +A Y       D +L H    ++A
Sbjct: 447 PPS-----PENTASSAPVDWRDPSQMEKLRNE-LAAYLCGSRREDRFLSHRPGPTVA 497


>gi|33946327 nucleoporin 214kDa [Homo sapiens]
          Length = 2090

 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 80/340 (23%), Positives = 124/340 (36%), Gaps = 60/340 (17%)

Query: 1011 PPPPPPPRRSYLP----------GSGLTTTRSGDV-VYTGRK-ENITAKASSEDAGPSPQ 1058
            PP  PPP  +  P          GS L++  +  + +  GR  E  T+ A  E  G S  
Sbjct: 1451 PPSAPPPTTAATPLPTSFPTLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEV 1510

Query: 1059 TRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAE-LQGSSGAPQTSRMPVP 1117
            + +     EE  SA  P  PP T+ S K E         ++A+    +SG   +S   V 
Sbjct: 1511 SASAASLLEEQQSAQLPQAPPQTSDSVKKEP--------VLAQPAVSNSGTAASSTSLVA 1562

Query: 1118 MSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSP-SLPASKIPALSPS-- 1174
            +SA+  P T   P  +++   P       G    +        P ++  S  P  S +  
Sbjct: 1563 LSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAISSAGPVAVETSSTPIASSTTS 1622

Query: 1175 ------SGKSSSLPSSSGDSSNLPNPPATKPSIASNPLS--------------------- 1207
                  S ++++  + +  SS    PPA   S A N L+                     
Sbjct: 1623 IVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLTNNTATAPSATPVFGQVAASTA 1682

Query: 1208 -----PQTGPPAHSASLIPSVSNGSLKFQSLTHTGKG--HHLSFSPQSQNGRAPPPLS-- 1258
                  QTG  A +A+  P VS+      +   T  G     +F   S  G++    +  
Sbjct: 1683 PSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVFGQTTFGQASVFGQSASSAASV 1742

Query: 1259 FSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSS 1298
            FS S P  +S  +  Q A  T T  + S+    +   SSS
Sbjct: 1743 FSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSSS 1782



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 72/293 (24%), Positives = 105/293 (35%), Gaps = 45/293 (15%)

Query: 962  NIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKS-------PPPPP 1014
            +++K+   L +     P   G  P         +P S Q  +KL   +       PP  P
Sbjct: 412  SLIKTPERLSLEGERQPKSPGSTPT--------TPTSSQAPQKLDASAAAAPASLPPSSP 463

Query: 1015 PPPRRSY--LPGSGLTTTRS-------GDVVYTGRKENITAKASSEDAGPSPQTRATKY- 1064
              P  ++  LP  G  T  S            TG   + ++ + S  A P P      + 
Sbjct: 464  AAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSKAAPGPGPSTFSFV 523

Query: 1065 PAEEPASAWTPSPPPVTTSSSK--------DEEEEEEEGDKIMAE--LQGSSGAPQTSRM 1114
            P  + + A TP+  PV  S++             E      + A       S  P TS +
Sbjct: 524  PPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNIAMKPSFPPSTSAV 583

Query: 1115 PVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPS 1174
             V +S K        P   S+   P     +      SG    PT  S P S +P     
Sbjct: 584  KVNLSEKFTAAATSTPVSSSQSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPL---- 639

Query: 1175 SGKSSSLPSSSGDS---SNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVS 1224
              KSS LPS SG S   S+ P P   + S    P + + G P  + SL P+V+
Sbjct: 640  --KSSVLPSPSGRSAQGSSSPVPSMVQKSPRITPPAAKPGSP-QAKSLQPAVA 689



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 35/103 (33%), Positives = 50/103 (48%), Gaps = 3/103 (2%)

Query: 1167 KIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNG 1226
            K P  +P++  SS  P    D+S    P +  PS  + P++  +  PA  A  + S  + 
Sbjct: 429  KSPGSTPTTPTSSQAPQKL-DASAAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSS 487

Query: 1227 SLKFQSLTHTGKG-HHLSFSPQSQNGRAPPPLSFSSSPPSPAS 1268
            SLK  S T TG+   + S S  S+    P P +FS  PPS AS
Sbjct: 488  SLK-SSATVTGEPPSYSSGSDSSKAAPGPGPSTFSFVPPSKAS 529



 Score = 31.2 bits (69), Expect = 6.8
 Identities = 48/196 (24%), Positives = 74/196 (37%), Gaps = 33/196 (16%)

Query: 1143 RQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGK-------SSSLPSSSGDSSNLPNPP 1195
            ++ + SA  +     P+SP+ P +   +L P+ G        SSSL SS+  +     PP
Sbjct: 445  QKLDASAAAAPASLPPSSPAAPIATF-SLLPAGGAPTVFSFGSSSLKSSATVTGE---PP 500

Query: 1196 ATKPSIASNPLSPQTGP------PAHSASL--IPSVSNGSLKFQSLTHTGKGHHLSFSPQ 1247
            +      S+  +P  GP      P   ASL   P+ S  +    S +    G   +    
Sbjct: 501  SYSSGSDSSKAAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLEST 560

Query: 1248 SQNGRAPPPLSFSSSPPSPASSVSLNQGAKGT-RTIHTP-------------SLTSYKAQ 1293
                 + P ++   S P   S+V +N   K T     TP             S  S  A 
Sbjct: 561  PVPSVSAPNIAMKPSFPPSTSAVKVNLSEKFTAAATSTPVSSSQSAPPMSPFSSASKPAA 620

Query: 1294 NGSSSKATPSTAKETS 1309
            +G  S  TP +A  +S
Sbjct: 621  SGPLSHPTPLSAPPSS 636



 Score = 31.2 bits (69), Expect = 6.8
 Identities = 44/173 (25%), Positives = 61/173 (35%), Gaps = 34/173 (19%)

Query: 1139 PRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLP-NPPAT 1197
            P     +   A  SGG  KP+  ++P S  P  S  +  S++ P     SS+ P  P  T
Sbjct: 1244 PSTKESSQPDAFSSGGGSKPSYEAIPESSPP--SGITSASNTTPGEPAASSSRPVAPSGT 1301

Query: 1198 KPSIASNPLSPQTGPPAHSASLIPSVSNGSL-----------KFQSLTHTGKGHHLSFS- 1245
              S  S+ L  +T P      L PS   G                S   T K    S + 
Sbjct: 1302 ALSTTSSKL--ETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTS 1359

Query: 1246 ---------PQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTS 1289
                     P   N  APP L   + PP  +S+         T ++  P+ TS
Sbjct: 1360 TQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSAT--------TTSVAPPAATS 1404


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 80/369 (21%), Positives = 122/369 (33%), Gaps = 43/369 (11%)

Query: 957  EEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPP---- 1012
            +E     +KS P     PA  P     AP       E +P + ++      K P P    
Sbjct: 230  KEPTPTTIKSAPTTPKEPA--PTTTKSAPTTP---KEPAPTTTKEPAPTTPKEPAPTTTK 284

Query: 1013 -PPPPPRRSY--LPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPA--- 1066
             P P   +S    P     TT       T ++   T         P      TK PA   
Sbjct: 285  EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT 344

Query: 1067 -EEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPG 1125
             +EPA      P P T         +E       A       +P T + P P + K+ P 
Sbjct: 345  PKEPAPTAPKKPAPTTPKEPAPTTPKEP------APTTTKEPSPTTPKEPAPTTTKSAPT 398

Query: 1126 TLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSS 1185
            T  +P   +    P   ++ + +  K      PT+P  PA   P     +      P++ 
Sbjct: 399  TTKEPAPTTTKSAPTTPKEPSPTTTKEPA---PTTPKEPAPTTPKKPAPTTPKEPAPTTP 455

Query: 1186 GDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFS 1245
             +    P P  TK    + P  P    P  +A   P         + LT T        +
Sbjct: 456  KE----PAPTTTKKPAPTTPKEPAPTTPKETAPTTP---------KKLTPTTPEKLAPTT 502

Query: 1246 PQSQNGRAPPPLSFSS----SPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSK-A 1300
            P+      P  L+ ++    +P +P         A    T   P+ T+ K    ++ K  
Sbjct: 503  PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 562

Query: 1301 TPSTAKETS 1309
             P+T KET+
Sbjct: 563  APTTPKETA 571



 Score = 54.3 bits (129), Expect = 8e-07
 Identities = 86/399 (21%), Positives = 131/399 (32%), Gaps = 54/399 (13%)

Query: 956  LEEAQANIMKSIPNLEMP---PATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSP-- 1010
            +++ + N  K  P  + P    A   L  GD  V   + S    N      K+    P  
Sbjct: 66   VKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPIN 125

Query: 1011 PPPPPPPRRSYLPGSGLT-----------TTRSGDVVYTGRKENITA--------KASSE 1051
            P P  PP       + LT           TT +     T  KE  T+        K S++
Sbjct: 126  PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 185

Query: 1052 DAGPSPQTRA---------TKYPA------------EEPASAWTPSPPPVTTSSSKDEEE 1090
            D  P+ +  A         TK PA            +EPAS     P P T  S+    +
Sbjct: 186  DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 245

Query: 1091 EEEEGDKIMAELQGSSGAPQTSRMPVPMSAKN-RPGTLDKPGKQSKLQDPRQYRQANGSA 1149
            E        A       AP T++ P P + K   P T  +P   +    P   ++   + 
Sbjct: 246  EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 305

Query: 1150 KKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQ 1209
             K      PT+P  PA   P     +      P++   +   P  PA        P +P+
Sbjct: 306  PKKPA---PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK 362

Query: 1210 TGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASS 1269
               P       P+ +    K  S T   +    +        + P P +  S+P +P   
Sbjct: 363  EPAPTTPKEPAPTTT----KEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 418

Query: 1270 VSLNQGAKGTRTIHTPSLTSYKAQNGSSSK-ATPSTAKE 1307
                       T   P+ T+ K    ++ K   P+T KE
Sbjct: 419  SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 457



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 80/364 (21%), Positives = 119/364 (32%), Gaps = 39/364 (10%)

Query: 957  EEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPPPP 1016
            E A     K  P     PA    P+  AP    +L+  +P      EKL   +P  P P 
Sbjct: 457  EPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTP------EKLAPTTPEKPAPT 509

Query: 1017 PRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPA----EEPA-- 1070
                  P    TT               T KA++ +    P     K PA    +EPA  
Sbjct: 510  TPEELAP----TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 565

Query: 1071 -----SAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPG 1125
                 +  TP     TT         ++   K +A          T   P P + K    
Sbjct: 566  TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 625

Query: 1126 TLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSS 1185
            T  K    +  ++P       G+A  +  +  PT+P  PA K   L+P++ K  +  S++
Sbjct: 626  TTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPKKPAPK--ELAPTTTKGPT--STT 680

Query: 1186 GDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFS 1245
             D      P  T P+    P       PA +    P  +   +   + T      H S  
Sbjct: 681  SDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD 740

Query: 1246 PQSQNGRA-PPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPST 1304
              +    A P P +  +SP  P           G  T  TP+ T  +    +  K T   
Sbjct: 741  ESTPELSAEPTPKALENSPKEP-----------GVPTTKTPAATKPEMTTTAKDKTTERD 789

Query: 1305 AKET 1308
             + T
Sbjct: 790  LRTT 793



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 69/306 (22%), Positives = 100/306 (32%), Gaps = 20/306 (6%)

Query: 871  PAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSI 930
            PA   P  A++P  P+E   T     AP +P+ P   +       +E    + K  A + 
Sbjct: 530  PAPTTPK-AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP------KETAPTTPKGTAPTT 582

Query: 931  EKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPL-PRGDAPVDKV 989
             K       K+        KE      +   +     P    P  T P  P+  AP    
Sbjct: 583  LKEPAPTTPKKPA-----PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 637

Query: 990  ELSEDSPNSEQDLE-KLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAK- 1047
            E +  +P        K    + P  P P   +     G T+T S     T  KE      
Sbjct: 638  EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 697

Query: 1048 ---ASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQG 1104
               A +    P+P T  T  P     S  T +  P T   S DE   E   +     L+ 
Sbjct: 698  KEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN 757

Query: 1105 SSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLP 1164
            S   P       P + K    T  K   ++  +D R   +   +A K   +   T+    
Sbjct: 758  SPKEPGVPTTKTPAATKPEMTTTAK--DKTTERDLRTTPETTTAAPKMTKETATTTEKTT 815

Query: 1165 ASKIPA 1170
             SKI A
Sbjct: 816  ESKITA 821


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 80/369 (21%), Positives = 122/369 (33%), Gaps = 43/369 (11%)

Query: 957  EEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPP---- 1012
            +E     +KS P     PA  P     AP       E +P + ++      K P P    
Sbjct: 271  KEPTPTTIKSAPTTPKEPA--PTTTKSAPTTP---KEPAPTTTKEPAPTTPKEPAPTTTK 325

Query: 1013 -PPPPPRRSY--LPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPA--- 1066
             P P   +S    P     TT       T ++   T         P      TK PA   
Sbjct: 326  EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT 385

Query: 1067 -EEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPG 1125
             +EPA      P P T         +E       A       +P T + P P + K+ P 
Sbjct: 386  PKEPAPTAPKKPAPTTPKEPAPTTPKEP------APTTTKEPSPTTPKEPAPTTTKSAPT 439

Query: 1126 TLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSS 1185
            T  +P   +    P   ++ + +  K      PT+P  PA   P     +      P++ 
Sbjct: 440  TTKEPAPTTTKSAPTTPKEPSPTTTKEPA---PTTPKEPAPTTPKKPAPTTPKEPAPTTP 496

Query: 1186 GDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFS 1245
             +    P P  TK    + P  P    P  +A   P         + LT T        +
Sbjct: 497  KE----PAPTTTKKPAPTTPKEPAPTTPKETAPTTP---------KKLTPTTPEKLAPTT 543

Query: 1246 PQSQNGRAPPPLSFSS----SPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSK-A 1300
            P+      P  L+ ++    +P +P         A    T   P+ T+ K    ++ K  
Sbjct: 544  PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 603

Query: 1301 TPSTAKETS 1309
             P+T KET+
Sbjct: 604  APTTPKETA 612



 Score = 54.3 bits (129), Expect = 8e-07
 Identities = 86/399 (21%), Positives = 131/399 (32%), Gaps = 54/399 (13%)

Query: 956  LEEAQANIMKSIPNLEMP---PATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSP-- 1010
            +++ + N  K  P  + P    A   L  GD  V   + S    N      K+    P  
Sbjct: 107  VKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPIN 166

Query: 1011 PPPPPPPRRSYLPGSGLT-----------TTRSGDVVYTGRKENITA--------KASSE 1051
            P P  PP       + LT           TT +     T  KE  T+        K S++
Sbjct: 167  PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 226

Query: 1052 DAGPSPQTRA---------TKYPA------------EEPASAWTPSPPPVTTSSSKDEEE 1090
            D  P+ +  A         TK PA            +EPAS     P P T  S+    +
Sbjct: 227  DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 286

Query: 1091 EEEEGDKIMAELQGSSGAPQTSRMPVPMSAKN-RPGTLDKPGKQSKLQDPRQYRQANGSA 1149
            E        A       AP T++ P P + K   P T  +P   +    P   ++   + 
Sbjct: 287  EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 346

Query: 1150 KKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQ 1209
             K      PT+P  PA   P     +      P++   +   P  PA        P +P+
Sbjct: 347  PKKPA---PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK 403

Query: 1210 TGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASS 1269
               P       P+ +    K  S T   +    +        + P P +  S+P +P   
Sbjct: 404  EPAPTTPKEPAPTTT----KEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 459

Query: 1270 VSLNQGAKGTRTIHTPSLTSYKAQNGSSSK-ATPSTAKE 1307
                       T   P+ T+ K    ++ K   P+T KE
Sbjct: 460  SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 498



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 80/364 (21%), Positives = 119/364 (32%), Gaps = 39/364 (10%)

Query: 957  EEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPPPP 1016
            E A     K  P     PA    P+  AP    +L+  +P      EKL   +P  P P 
Sbjct: 498  EPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTP------EKLAPTTPEKPAPT 550

Query: 1017 PRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPA----EEPA-- 1070
                  P    TT               T KA++ +    P     K PA    +EPA  
Sbjct: 551  TPEELAP----TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 606

Query: 1071 -----SAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPG 1125
                 +  TP     TT         ++   K +A          T   P P + K    
Sbjct: 607  TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 666

Query: 1126 TLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSS 1185
            T  K    +  ++P       G+A  +  +  PT+P  PA K   L+P++ K  +  S++
Sbjct: 667  TTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPKKPAPK--ELAPTTTKGPT--STT 721

Query: 1186 GDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFS 1245
             D      P  T P+    P       PA +    P  +   +   + T      H S  
Sbjct: 722  SDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD 781

Query: 1246 PQSQNGRA-PPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPST 1304
              +    A P P +  +SP  P           G  T  TP+ T  +    +  K T   
Sbjct: 782  ESTPELSAEPTPKALENSPKEP-----------GVPTTKTPAATKPEMTTTAKDKTTERD 830

Query: 1305 AKET 1308
             + T
Sbjct: 831  LRTT 834



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 69/306 (22%), Positives = 100/306 (32%), Gaps = 20/306 (6%)

Query: 871  PAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSI 930
            PA   P  A++P  P+E   T     AP +P+ P   +       +E    + K  A + 
Sbjct: 571  PAPTTPK-AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP------KETAPTTPKGTAPTT 623

Query: 931  EKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPL-PRGDAPVDKV 989
             K       K+        KE      +   +     P    P  T P  P+  AP    
Sbjct: 624  LKEPAPTTPKKPA-----PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 678

Query: 990  ELSEDSPNSEQDLE-KLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAK- 1047
            E +  +P        K    + P  P P   +     G T+T S     T  KE      
Sbjct: 679  EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 738

Query: 1048 ---ASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQG 1104
               A +    P+P T  T  P     S  T +  P T   S DE   E   +     L+ 
Sbjct: 739  KEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN 798

Query: 1105 SSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLP 1164
            S   P       P + K    T  K   ++  +D R   +   +A K   +   T+    
Sbjct: 799  SPKEPGVPTTKTPAATKPEMTTTAK--DKTTERDLRTTPETTTAAPKMTKETATTTEKTT 856

Query: 1165 ASKIPA 1170
             SKI A
Sbjct: 857  ESKITA 862


>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
          Length = 2089

 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 142/702 (20%), Positives = 245/702 (34%), Gaps = 87/702 (12%)

Query: 653  KVMETMKRLEDPVQRQRVLVEQERQKYLHEEEKIVKKLCELEDFVEDLKKDSTAASRLVT 712
            KVM   K   + V  +R  +E+E +K L E +  V          E+L K          
Sbjct: 812  KVMGIPKETAERVGPERGPLERETEKLLPERQTDVTG-------EEELTKGK-------- 856

Query: 713  LKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMRAILRIEVEAVRFLKEEPHKLDSLLKRV 772
             +D E    L R      +   GE  + +   R  L++E+E    ++E+  +  +L  + 
Sbjct: 857  -QDREQKQLLARDTQRQESDKNGESASPERD-RESLKVEIETSEEIQEKQVQKQTLPSKA 914

Query: 773  RSMTDVLTMLRRHVTDGLLKGTDAAQAAQYMAMEKATAAEVLKSQEEAAHTSGQPFHSTG 832
                     + R V +      +  +    + +E+ T     + +  +    GQ    T 
Sbjct: 915  FERE-----VERPVANRECDPAELEEKVPKVILERDTQRG--EPEGGSQDQKGQASSPTP 967

Query: 833  APGDAKSEVV-PLSGMMVRHAQS----SPVVIQPSQHSVALLN----PAQNLPHVASSPA 883
             PG    ++  P S  +   +QS    SPV   P +H   LLN    PA+    + ++  
Sbjct: 968  EPGVGAGDLPGPTSAPVPSGSQSGGRGSPV--SPRRHQKGLLNCKMPPAEKASRIRAAEK 1025

Query: 884  VPQ------EATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKKW 937
            V +      +A     + +AP  PQ P+N  + + L    + S    +   ++ K  +  
Sbjct: 1026 VSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDG 1085

Query: 938  EEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPN 997
             ++          E E    + +    KS   +   PAT   P         +     P 
Sbjct: 1086 SQEAPEAPL--SSELEPFHPKPKIRTRKS-SRMTPFPATSAAPEPHPSTSTAQPVTPKPT 1142

Query: 998  SEQDLEKLGGKSPPPPPP--PPRRSYLPGSGL---TTTRSGDVVYTGRKENITAKASSED 1052
            S+    +    S   P P  P      P +      T+     V  GRK   + K + E 
Sbjct: 1143 SQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVK-TPET 1201

Query: 1053 AGPS-----PQTRATKYPAEEPASAWT----------------PSPPPVTTSSSKDEEEE 1091
              P+     P T   +    EP S  T                P+ P +  S+S D+   
Sbjct: 1202 VVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVT 1261

Query: 1092 EEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKK 1151
             E   +     +  S   +T    VP + + RP T        K        + N S+ K
Sbjct: 1262 SEPTYQATRGRKNRSSV-KTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVK 1320

Query: 1152 SGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTG 1211
            +     PT+P L  S       +   +S    S  + S++ NP +T P     P S  T 
Sbjct: 1321 TPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTE 1380

Query: 1212 PPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAP--PPLSFSSSPPSPASS 1269
             P     + P  ++ + + +    +GK      +P++    AP   P + +  P +P  +
Sbjct: 1381 QP-----VTPEPTSRATRGRKNRSSGK------TPETLVPTAPKLEPSTSTDQPVTPEPT 1429

Query: 1270 VSLNQGAKGTRTIHTPSLTSYKAQNGSSSKAT--PSTAKETS 1309
                +G     ++ TP      A     S +T  P T + TS
Sbjct: 1430 SQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTS 1471



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 49/249 (19%), Positives = 93/249 (37%), Gaps = 14/249 (5%)

Query: 973  PPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRS 1032
            P  T    RG      V+  E    +  +L+       P    P  R+       ++ ++
Sbjct: 1467 PEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKT 1526

Query: 1033 GDVVYTGRKENITAKASSEDAGPSPQTRATK----YPAEEPASAWTPSPPPVTTSSSKDE 1088
             + V     E   + ++ +   P P +RAT+      + +   +  P  P +  S+S+++
Sbjct: 1527 PETVVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQ 1586

Query: 1089 EEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGS 1148
                E   +     + +  + +T    VP + +  P T        KL      R+ N S
Sbjct: 1587 LVTPEPTSR-ATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRS 1645

Query: 1149 AKK-------SGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPA-TKPS 1200
            + K       +  D +P +P+   S  P      G+S +L SS+  +  +P  P    P 
Sbjct: 1646 SVKTPKPVEPAASDLEPFTPT-DQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEFQSPV 1704

Query: 1201 IASNPLSPQ 1209
                P+SP+
Sbjct: 1705 TTDQPISPE 1713



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 81/427 (18%), Positives = 148/427 (34%), Gaps = 35/427 (8%)

Query: 876  PHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEE--------IHSVSAKNRA 927
            P V ++P + Q +TST Q   +  + Q+     +  S+   E        +   ++ +R 
Sbjct: 1160 PVVPTAPEL-QPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRP 1218

Query: 928  VSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVD 987
            V+ E   +    ++        +       E Q +     P    P  T    RG     
Sbjct: 1219 VTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEP--TYQATRGRKNRS 1276

Query: 988  KVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAK 1047
             V+  E    +  +L        P  P P  R+    + +++ ++ + V     E   + 
Sbjct: 1277 SVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQIST 1336

Query: 1048 ASSEDAGPSPQTRATKY-----PAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAEL 1102
            ++ +   P P +R T+        + P S   P  P +  S+S ++    E   +     
Sbjct: 1337 STDQPVTPKPTSRTTRSRTNMSSVKNPEST-VPIAPELPPSTSTEQPVTPEPTSRATRGR 1395

Query: 1103 QGSSGAPQTSRMPVPMSAKNRPGT-LDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSP 1161
            +  S   +T    VP + K  P T  D+P          + R  N S+ K+     PT+P
Sbjct: 1396 KNRSSG-KTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGR-TNRSSVKTPETVVPTAP 1453

Query: 1162 SLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIP 1221
             L  S       +   +S       D S++  P    P+      S  T  P  S     
Sbjct: 1454 ELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEP--- 1510

Query: 1222 SVSNGSLKFQSLTHTGKGHHLSF-SPQSQNGRAP--PPLSFSSSPPSPASSVSLNQGAKG 1278
                      S T  G+ +  S  +P++    AP   P + +  P +P  +    +G   
Sbjct: 1511 ---------TSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRTN 1561

Query: 1279 TRTIHTP 1285
              ++ TP
Sbjct: 1562 RSSVKTP 1568


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
          Length = 816

 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 72/307 (23%), Positives = 106/307 (34%), Gaps = 57/307 (18%)

Query: 1006 GGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTG------------------RKENITAK 1047
            G ++PP     P     PG    TTR G +   G                  ++  ++A 
Sbjct: 91   GERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAG 150

Query: 1048 ASSEDAGPSPQTRATKYPAEEPASAWTPS-PPPVTTSSSKDEEEEEEEGDKIMAELQGSS 1106
            A  + +GP+P T +        A+      P P  ++  +   E   +     +E   + 
Sbjct: 151  ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE 210

Query: 1107 GAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDP-RQYRQANGSAKKSGGDFKPTSPSLPA 1165
             +P   R P       RP +       + L  P R    A G+ +      +P    L A
Sbjct: 211  PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA 270

Query: 1166 SK-----------IPALSPSSGKSSSLPSSSGDSS--------NLPNPPATKPSIASNPL 1206
             +            PAL P S    + PS S   S         LP+PPAT PS A+  L
Sbjct: 271  LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSL 330

Query: 1207 SPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSP 1266
               T    H  S +PS     L              +  PQ+    A PPL    +PPSP
Sbjct: 331  GSPTLQATH--SFLPSPPLSPL-------------ATPPPQAPPALALPPL---QAPPSP 372

Query: 1267 ASSVSLN 1273
             +S  L+
Sbjct: 373  PASPPLS 379



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 77/347 (22%), Positives = 110/347 (31%), Gaps = 56/347 (16%)

Query: 955  LLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPP 1014
            L   A  ++  S   L  P  +GP  RG  P      S+  P   Q L        PP  
Sbjct: 225  LQRPASRSLSSSATPLSSPARSGPSARG-TPRAPAHPSQPKPKGLQALR-------PPQV 276

Query: 1015 PPPRRSYLPGSG------LTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEE 1068
             PPR+   P  G      L T             ++    S     PS  T +   P  +
Sbjct: 277  TPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQ 336

Query: 1069 PASAWTPSPP--PVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRM-PVPMSAKNRPG 1125
               ++ PSPP  P+ T   +            +  LQ     P +  + P+   +   P 
Sbjct: 337  ATHSFLPSPPLSPLATPPPQAPPA------LALPPLQAPPSPPASPPLSPLATPSPQAPN 390

Query: 1126 TL------------DKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSP 1173
             L              P  Q+    P     +  +   S       +P L     P  SP
Sbjct: 391  ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP 450

Query: 1174 SSGKSSSLPSSSGDSSNLPN------PPATKPSIASNPLSPQTGPPAHSASLIPSVSNGS 1227
                S++ P  +      P       PP   P++A+ PL     PPA      P   + S
Sbjct: 451  PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 510

Query: 1228 LKFQSLTHTGKGHHLSFSPQSQNGRAPPPLS--FSSSPPSPASSVSL 1272
            L    L           +P  Q   APP L+      PPSP +S +L
Sbjct: 511  LPMSPLA----------TPPPQ---APPVLAAPLLQVPPSPPASPTL 544



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 74/318 (23%), Positives = 106/318 (33%), Gaps = 58/318 (18%)

Query: 1007 GKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPA 1066
            G   PPPP  P    + G+     R       G     T   S+  AGP+  +R      
Sbjct: 31   GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSR------ 84

Query: 1067 EEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPGT 1126
              PAS      PP   +S                        P     P   S   RPG 
Sbjct: 85   -PPASGRGERAPPAKNTS------------------------PGPVSSPGRASGTTRPGP 119

Query: 1127 LDKPGKQSKLQDPRQYRQANGSAKK---SGGDFKPTSPSLPASKIPAL---SPSSGKSSS 1180
            L + G +   ++     +A  + K+   S G  + TS   P +  PA+   S ++G    
Sbjct: 120  LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 179

Query: 1181 LPSSSGDSSNLPNPPATKP-SIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKG 1239
            LP  +   S  P PP   P    S+     T  P+ +A   PS   G  +  S + +   
Sbjct: 180  LPRPA--PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA 237

Query: 1240 HHLSFSPQS-QNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQN---- 1294
              LS   +S  + R  P      S P P          KG + +  P +T  +       
Sbjct: 238  TPLSSPARSGPSARGTPRAPAHPSQPKP----------KGLQALRPPQVTPPRKDAAPAL 287

Query: 1295 ---GSSSKATPSTAKETS 1309
                SS  ATPS +   S
Sbjct: 288  GPLSSSPLATPSPSAPPS 305



 Score = 34.7 bits (78), Expect = 0.62
 Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 13/84 (15%)

Query: 295 PGAPRPGSTAHPPHAIPNSPPSTP--VPHSMPPSPSRIPYGGTRSMVV-------PGNAT 345
           P +  P S A PP  +P SPP++P   P + PP  +  P       +        P  AT
Sbjct: 427 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT 486

Query: 346 IPRDRISSLPVS----RPISPSPS 365
            P   + S P S     P SPS S
Sbjct: 487 PPLQALPSPPASFPGQAPFSPSAS 510



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 28/83 (33%), Positives = 31/83 (37%), Gaps = 14/83 (16%)

Query: 295 PGAPRPGSTAHPPHAIPNS------------PPSTPV--PHSMPPSPSRIPYGGTRSMVV 340
           P +P     A P    PN+            PPS PV  P S P SP   P     S   
Sbjct: 373 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 432

Query: 341 PGNATIPRDRISSLPVSRPISPS 363
           P  A  P     S P S P+SPS
Sbjct: 433 PSLAAPPLQVPPSPPASPPMSPS 455



 Score = 33.1 bits (74), Expect = 1.8
 Identities = 37/127 (29%), Positives = 53/127 (41%), Gaps = 17/127 (13%)

Query: 960  QANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRR 1019
            QA  + + P L++PP+    P   AP          P++     +L     P PPPPP R
Sbjct: 522  QAPPVLAAPLLQVPPSPPASPTLQAPRRP---PTPGPDTSVSGPRLTLALAPGPPPPPSR 578

Query: 1020 SYLPGSGLTTTRSGDVVYTGRKENITA---KASSEDAGPSPQTRATKYPAEEPA----SA 1072
            S  P S    T SG  +  G   + T+   +    D+GP     A+  P  E A    +A
Sbjct: 579  S--PSS----TLSGPDL-AGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAA 631

Query: 1073 WTPSPPP 1079
            W+  P P
Sbjct: 632  WSRGPAP 638



 Score = 31.6 bits (70), Expect = 5.2
 Identities = 26/82 (31%), Positives = 29/82 (35%), Gaps = 15/82 (18%)

Query: 295 PGAPRPGSTAHPPHAIPNSPPSTP--------------VPHSMPPSPSRIPYGGTRSMVV 340
           P AP P  +A P      SPP+TP                HS  PSP   P         
Sbjct: 300 PSAP-PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP 358

Query: 341 PGNATIPRDRISSLPVSRPISP 362
           P  A  P     S P S P+SP
Sbjct: 359 PALALPPLQAPPSPPASPPLSP 380


>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
          Length = 1120

 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 91/324 (28%), Positives = 126/324 (38%), Gaps = 55/324 (16%)

Query: 995  SPNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITA---KASSE 1051
            +P S+    +   K PPPPPP    S    SG +          G KE  T    +  SE
Sbjct: 771  TPRSQSFALRARRKGPPPPPPKRLSSV---SGPSPEPPPLDESPGPKEGATGPRRRTLSE 827

Query: 1052 DAGPS-------PQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQG 1104
             AGPS       P   A+    EEP     P   P +  SS +     EEG+  + +   
Sbjct: 828  PAGPSEPPGPPAPAGPASDTEEEEPG----PEGTPPSRGSSGEGLPFAEEGNLTIKQRPK 883

Query: 1105 SSGAPQTSRMPVPM----------SAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGG 1154
             +G P     PVP           + K RP   ++   Q+ L        A G A  + G
Sbjct: 884  PAG-PPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTAL-------LAFGVASATPG 935

Query: 1155 DFKP-TSP----SLPASKIPALSPSSGKSSSLPSSSGDSSNL--PNPPATKPSIASNPLS 1207
               P  SP    S PAS +P   PSS  +  +P+    S  +  P PP   P + S+  S
Sbjct: 936  PAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLESSAAS 995

Query: 1208 ---PQTGPPAHSASLIPSVSNGSL-KFQSLTHTGKGHHLSFS-PQSQNGRAPPPLSFSSS 1262
                +T PPA  A+L+     G+  K  S+  T     L+FS P+      P P+     
Sbjct: 996  RWNGETEPPAAPAALLKVPGAGTAPKPVSVACT----QLAFSGPKLAPRLGPRPV----P 1047

Query: 1263 PPSPASSVSLNQGAKGTRTIHTPS 1286
            PP P S+ ++  G    R   T S
Sbjct: 1048 PPRPESTGTVGPGQAQQRLEQTSS 1071



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 74/327 (22%), Positives = 110/327 (33%), Gaps = 46/327 (14%)

Query: 954  KLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPP 1013
            +L +  +   ++ + N E P   GP       +   + SE SP  E      GG   P P
Sbjct: 556  RLAKGPELMAIEGLENGEGPATAGPR------LLTFQGSELSP--ELQAAMAGGGPEPLP 607

Query: 1014 PPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTR----ATKYPAEEP 1069
             PP R       G  +  SG       +E    + S  D  P PQ R     T+ P +  
Sbjct: 608  LPPARSPSQESIGARSRGSGH-----SQEQPAPQPSGGDPSP-PQERNLPEGTERPPKLC 661

Query: 1070 ASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPGTLDK 1129
            +S     PPP      +        G    A    S  A   +  P P   K R  +L +
Sbjct: 662  SSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSR 721

Query: 1130 PGKQSKLQDPRQYRQANGSAKKSGGDF-----KPTSPSLPASKIPALSPSSGKSSSLPSS 1184
            PG      +     +A G    + G +     +P   +L  +  P+++P+  + +    S
Sbjct: 722  PGPTEGDAEG----EAEGPVGSTLGSYATLTRRPGRSALVRTS-PSVTPTPARGTPRSQS 776

Query: 1185 SGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSF 1244
                +    PP   P   S+   P   PP    S  P    G+        TG       
Sbjct: 777  FALRARRKGPPPPPPKRLSSVSGPSPEPPPLDES--PGPKEGA--------TGPRRRTLS 826

Query: 1245 SPQSQNGRAPPPLSFSSSPPSPASSVS 1271
             P    G + PP      PP+PA   S
Sbjct: 827  EPA---GPSEPP-----GPPAPAGPAS 845


>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
          Length = 1202

 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 91/324 (28%), Positives = 126/324 (38%), Gaps = 55/324 (16%)

Query: 995  SPNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITA---KASSE 1051
            +P S+    +   K PPPPPP    S    SG +          G KE  T    +  SE
Sbjct: 853  TPRSQSFALRARRKGPPPPPPKRLSSV---SGPSPEPPPLDESPGPKEGATGPRRRTLSE 909

Query: 1052 DAGPS-------PQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQG 1104
             AGPS       P   A+    EEP     P   P +  SS +     EEG+  + +   
Sbjct: 910  PAGPSEPPGPPAPAGPASDTEEEEPG----PEGTPPSRGSSGEGLPFAEEGNLTIKQRPK 965

Query: 1105 SSGAPQTSRMPVPM----------SAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGG 1154
             +G P     PVP           + K RP   ++   Q+ L        A G A  + G
Sbjct: 966  PAG-PPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTAL-------LAFGVASATPG 1017

Query: 1155 DFKP-TSP----SLPASKIPALSPSSGKSSSLPSSSGDSSNL--PNPPATKPSIASNPLS 1207
               P  SP    S PAS +P   PSS  +  +P+    S  +  P PP   P + S+  S
Sbjct: 1018 PAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLESSAAS 1077

Query: 1208 ---PQTGPPAHSASLIPSVSNGSL-KFQSLTHTGKGHHLSFS-PQSQNGRAPPPLSFSSS 1262
                +T PPA  A+L+     G+  K  S+  T     L+FS P+      P P+     
Sbjct: 1078 RWNGETEPPAAPAALLKVPGAGTAPKPVSVACT----QLAFSGPKLAPRLGPRPV----P 1129

Query: 1263 PPSPASSVSLNQGAKGTRTIHTPS 1286
            PP P S+ ++  G    R   T S
Sbjct: 1130 PPRPESTGTVGPGQAQQRLEQTSS 1153



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 74/327 (22%), Positives = 110/327 (33%), Gaps = 46/327 (14%)

Query: 954  KLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPP 1013
            +L +  +   ++ + N E P   GP       +   + SE SP  E      GG   P P
Sbjct: 638  RLAKGPELMAIEGLENGEGPATAGPR------LLTFQGSELSP--ELQAAMAGGGPEPLP 689

Query: 1014 PPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTR----ATKYPAEEP 1069
             PP R       G  +  SG       +E    + S  D  P PQ R     T+ P +  
Sbjct: 690  LPPARSPSQESIGARSRGSGH-----SQEQPAPQPSGGDPSP-PQERNLPEGTERPPKLC 743

Query: 1070 ASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPGTLDK 1129
            +S     PPP      +        G    A    S  A   +  P P   K R  +L +
Sbjct: 744  SSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSR 803

Query: 1130 PGKQSKLQDPRQYRQANGSAKKSGGDF-----KPTSPSLPASKIPALSPSSGKSSSLPSS 1184
            PG      +     +A G    + G +     +P   +L  +  P+++P+  + +    S
Sbjct: 804  PGPTEGDAEG----EAEGPVGSTLGSYATLTRRPGRSALVRTS-PSVTPTPARGTPRSQS 858

Query: 1185 SGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSF 1244
                +    PP   P   S+   P   PP    S  P    G+        TG       
Sbjct: 859  FALRARRKGPPPPPPKRLSSVSGPSPEPPPLDES--PGPKEGA--------TGPRRRTLS 908

Query: 1245 SPQSQNGRAPPPLSFSSSPPSPASSVS 1271
             P    G + PP      PP+PA   S
Sbjct: 909  EPA---GPSEPP-----GPPAPAGPAS 927


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 82/321 (25%), Positives = 119/321 (37%), Gaps = 58/321 (18%)

Query: 972  MPPATGP--LPRGDAPVDKVELSEDS------PNSEQDLEKLGGKSP----PPPPPPPRR 1019
            +PP  G   +P G  P  +   +E S      P+S   LE+  G SP    PP P  P  
Sbjct: 527  LPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQ--GPSPGDGSPPKPKDPVS 584

Query: 1020 SYLPGSGLTTTRSGDVVYTGRKENITAKASSE--------DAGPSPQT--RATKYPAEEP 1069
            + +P  G    R+   + +G+ +   A  S +         AGPSP T  RA K PA  P
Sbjct: 585  AAVPAPG----RNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAP 640

Query: 1070 ASAWTPSP-PPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPGTLD 1128
                 P P  P   SSS   +       K           P  S  P        PG   
Sbjct: 641  PKPGNPPPGHPGGQSSSGTSQHPPSLSPK----------PPTRSPSPPTQHTGQPPG--- 687

Query: 1129 KPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSS---GKSSSLPSSS 1185
            +P   S+L  PR+Y  ++  +     +  P  P   A+ +    P+S       +LPS  
Sbjct: 688  QPSAPSQLSAPRRY--SSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEH 745

Query: 1186 GDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFS 1245
            G    L  P  T P   + P +P  G    S     +++ G+ +  +  H G        
Sbjct: 746  G----LEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPE-TAQPHAGTLPRPRPV 800

Query: 1246 PQSQNGRAPPPLSFSSSPPSP 1266
            P+ +N  + PP      PP P
Sbjct: 801  PKPRNRPSVPP------PPQP 815



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 63/293 (21%), Positives = 94/293 (32%), Gaps = 45/293 (15%)

Query: 1011 PPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPA 1070
            PP PP    + +P       +S     +     + + A   + GPSP   +   P ++P 
Sbjct: 525  PPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKP-KDPV 583

Query: 1071 SAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPGTLDKP 1130
            SA  P+P    +  +  + + +          Q S G P  +  P P + +     + KP
Sbjct: 584  SAAVPAPGRNNSQIASGQNQPQAAA----GSHQLSMGQPHNAAGPSPHTLRR---AVKKP 636

Query: 1131 GKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSN 1190
                                       P  P  P    P    SSG S   PS S     
Sbjct: 637  AP------------------------APPKPGNPPPGHPGGQSSSGTSQHPPSLS----- 667

Query: 1191 LPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQN 1250
             P PP   PS    P +  TG P    S    +S       SL+     +H    P +Q 
Sbjct: 668  -PKPPTRSPS----PPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQ- 721

Query: 1251 GRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPS 1303
              A P +    +   P + ++L       +  HTP  T          K  PS
Sbjct: 722  --ATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPS 772



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 61/235 (25%), Positives = 85/235 (36%), Gaps = 28/235 (11%)

Query: 1082 TSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPV-PMSAKNRPGTLDKPGKQSKLQDPR 1140
            T +  D    E +    MA ++G     ++  + +    A  R GTL++       Q P 
Sbjct: 468  TGNDSDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHISPAFQPPL 527

Query: 1141 QYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPS 1200
                        G    P  P  P     A S S G   ++PSS+G     P+P    P 
Sbjct: 528  P--------PTDGSTVVPAGPEPPPQSSRAESSSGG--GTVPSSAGILEQGPSPGDGSPP 577

Query: 1201 IASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSF-SPQSQNGRAPPPLSF 1259
               +P+S     P  + S I S  N     Q     G  H LS   P +  G +P  L  
Sbjct: 578  KPKDPVSAAVPAPGRNNSQIASGQN-----QPQAAAG-SHQLSMGQPHNAAGPSPHTLRR 631

Query: 1260 SSSPPSPASSVSLN--------QGAKGTRTIHTPSLTSYKAQNGSSSKATPSTAK 1306
            +   P+PA     N        Q + GT + H PSL S K    S S  T  T +
Sbjct: 632  AVKKPAPAPPKPGNPPPGHPGGQSSSGT-SQHPPSL-SPKPPTRSPSPPTQHTGQ 684



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 31/109 (28%), Positives = 42/109 (38%), Gaps = 13/109 (11%)

Query: 266 PAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRPGS--TAHPPHAIPNSPPSTPVPHSM 323
           P  A NH P            L++ + +  G P P +  + H      ++PP TP P S 
Sbjct: 707 PIQAPNHPPPQ---PPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPST 763

Query: 324 PPSPSRIP--------YGGTRSMVVPGNATIPRDRISSLPVSRPISPSP 364
           PP   + P         GG      P   T+PR R    P +RP  P P
Sbjct: 764 PPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPP 812



 Score = 31.2 bits (69), Expect = 6.8
 Identities = 30/110 (27%), Positives = 41/110 (37%), Gaps = 22/110 (20%)

Query: 266 PAHAFNHTPKTMNGDMRMQRELVYARGDGP-----GAPRPGSTAHPPHAIPNSP---PST 317
           P +A   +P T+   ++         G+ P     G    G++ HPP   P  P   PS 
Sbjct: 618 PHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSP 677

Query: 318 PVPHS--MPPSPSRIPYGGTRSMVVPGNATIPRDRISSL-PVSRPISPSP 364
           P  H+   P  PS            P   + PR   SSL P+  P  P P
Sbjct: 678 PTQHTGQPPGQPS-----------APSQLSAPRRYSSSLSPIQAPNHPPP 716


>gi|54860105 nadrin isoform 2 [Homo sapiens]
          Length = 803

 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 80/325 (24%), Positives = 118/325 (36%), Gaps = 46/325 (14%)

Query: 957  EEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLE-KLGGKSPPPPPP 1015
            EE + N+ ++   L  P +      G+   D   L    P S   +E  L  K  PP P 
Sbjct: 444  EEVEFNVSEAFVPLTTPSSNHSFHTGNDS-DSGTLERKRPASMAVMEGDLVKKESPPKPK 502

Query: 1016 PPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSE--------DAGPSPQT--RATKYP 1065
             P  + +P  G    R+   + +G+ +   A  S +         AGPSP T  RA K P
Sbjct: 503  DPVSAAVPAPG----RNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKP 558

Query: 1066 AEEPASAWTPSP-PPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRP 1124
            A  P     P P  P   SSS   +       K           P  S  P        P
Sbjct: 559  APAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPK----------PPTRSPSPPTQHTGQPP 608

Query: 1125 GTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSS---GKSSSL 1181
            G   +P   S+L  PR+Y  ++  +     +  P  P   A+ +    P+S       +L
Sbjct: 609  G---QPSAPSQLSAPRRY--SSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMAL 663

Query: 1182 PSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHH 1241
            PS  G    L  P  T P   + P +P  G    S     +++ G+ +  +  H G    
Sbjct: 664  PSEHG----LEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPE-TAQPHAGTLPR 718

Query: 1242 LSFSPQSQNGRAPPPLSFSSSPPSP 1266
                P+ +N  + PP      PP P
Sbjct: 719  PRPVPKPRNRPSVPP------PPQP 737



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 31/109 (28%), Positives = 42/109 (38%), Gaps = 13/109 (11%)

Query: 266 PAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRPGS--TAHPPHAIPNSPPSTPVPHSM 323
           P  A NH P            L++ + +  G P P +  + H      ++PP TP P S 
Sbjct: 629 PIQAPNHPPPQ---PPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPST 685

Query: 324 PPSPSRIP--------YGGTRSMVVPGNATIPRDRISSLPVSRPISPSP 364
           PP   + P         GG      P   T+PR R    P +RP  P P
Sbjct: 686 PPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPP 734



 Score = 32.3 bits (72), Expect = 3.1
 Identities = 47/217 (21%), Positives = 75/217 (34%), Gaps = 18/217 (8%)

Query: 1094 EGDKIMAELQGSSGAPQTSRMPVP-------MSAKNRPGTLDKPGKQSKLQDPRQYRQAN 1146
            EGD +  E       P ++ +P P        S +N+P          +L   + +  A 
Sbjct: 489  EGDLVKKESPPKPKDPVSAAVPAPGRNNSQIASGQNQP---QAAAGSHQLSMGQPHNAAG 545

Query: 1147 GSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPL 1206
             S        K  +P+ P    P      G+SSS     G S + P+     P+ + +P 
Sbjct: 546  PSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSS-----GTSQHPPSLSPKPPTRSPSPP 600

Query: 1207 SPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSP 1266
            +  TG P    S    +S       SL+     +H    P +Q   A P +    +   P
Sbjct: 601  TQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQ---ATPLMHTKPNSQGP 657

Query: 1267 ASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPS 1303
             + ++L       +  HTP  T          K  PS
Sbjct: 658  PNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPS 694



 Score = 31.2 bits (69), Expect = 6.8
 Identities = 30/110 (27%), Positives = 41/110 (37%), Gaps = 22/110 (20%)

Query: 266 PAHAFNHTPKTMNGDMRMQRELVYARGDGP-----GAPRPGSTAHPPHAIPNSP---PST 317
           P +A   +P T+   ++         G+ P     G    G++ HPP   P  P   PS 
Sbjct: 540 PHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSP 599

Query: 318 PVPHS--MPPSPSRIPYGGTRSMVVPGNATIPRDRISSL-PVSRPISPSP 364
           P  H+   P  PS            P   + PR   SSL P+  P  P P
Sbjct: 600 PTQHTGQPPGQPS-----------APSQLSAPRRYSSSLSPIQAPNHPPP 638


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.125    0.354 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,334,609
Number of Sequences: 37866
Number of extensions: 3538307
Number of successful extensions: 39333
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 227
Number of HSP's successfully gapped in prelim test: 1839
Number of HSP's that attempted gapping in prelim test: 23670
Number of HSP's gapped (non-prelim): 13429
length of query: 1309
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1195
effective length of database: 13,930,794
effective search space: 16647298830
effective search space used: 16647298830
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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