BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|71143143 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 isoform 1 [Homo sapiens] (243 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|71143143 killer cell immunoglobulin-like receptor, two domain... 510 e-145 gi|71143139 killer cell immunoglobulin-like receptor, two domain... 332 1e-91 gi|134304833 killer cell immunoglobulin-like receptor, two domai... 308 4e-84 gi|134268644 killer cell immunoglobulin-like receptor, three dom... 305 2e-83 gi|110611923 killer cell immunoglobulin-like receptor, two domai... 302 2e-82 gi|134268642 killer cell immunoglobulin-like receptor, three dom... 278 2e-75 gi|11968154 killer cell immunoglobulin-like receptor, two domain... 271 3e-73 gi|66267727 killer cell immunoglobulin-like receptor, two domain... 266 9e-72 gi|124107606 killer cell immunoglobulin-like receptor, two domai... 265 4e-71 gi|6912472 killer cell immunoglobulin-like receptor, two domains... 254 5e-68 gi|46488946 killer cell immunoglobulin-like receptor, three doma... 238 5e-63 gi|7657277 killer cell immunoglobulin-like receptor, two domains... 233 1e-61 gi|6912474 killer cell immunoglobulin-like receptor, two domains... 228 5e-60 gi|116517309 killer cell immunoglobulin-like receptor, two domai... 226 1e-59 gi|134304835 killer cell immunoglobulin-like receptor, two domai... 224 7e-59 gi|124107610 killer cell immunoglobulin-like receptor, two domai... 199 1e-51 gi|62632748 killer-cell Ig-like receptor [Homo sapiens] 186 2e-47 gi|134133244 killer cell immunoglobulin-like receptor, three dom... 171 7e-43 gi|124107604 killer cell immunoglobulin-like receptor, two domai... 154 7e-38 gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B... 111 6e-25 gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B... 110 1e-24 gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B... 107 7e-24 gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B... 107 7e-24 gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B... 103 1e-22 gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B... 103 2e-22 gi|125987588 leukocyte immunoglobulin-like receptor, subfamily B... 102 2e-22 gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B... 102 2e-22 gi|125987593 leukocyte immunoglobulin-like receptor, subfamily B... 102 2e-22 gi|125987591 leukocyte immunoglobulin-like receptor, subfamily B... 102 2e-22 gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B... 102 3e-22 >gi|71143143 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 isoform 1 [Homo sapiens] Length = 243 Score = 510 bits (1313), Expect = e-145 Identities = 243/243 (100%), Positives = 243/243 (100%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL Sbjct: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV Sbjct: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120 Query: 121 SVTGNPSNSWPSPTEPSSETGNPRHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVM 180 SVTGNPSNSWPSPTEPSSETGNPRHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVM Sbjct: 121 SVTGNPSNSWPSPTEPSSETGNPRHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVM 180 Query: 181 DQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPN 240 DQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPN Sbjct: 181 DQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPN 240 Query: 241 AEP 243 AEP Sbjct: 241 AEP 243 >gi|71143139 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 isoform 2 [Homo sapiens] Length = 341 Score = 332 bits (852), Expect = 1e-91 Identities = 165/220 (75%), Positives = 179/220 (81%), Gaps = 2/220 (0%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 G++ KPSL A PGP V + E+V L C S + + L REG+ + G +G +A Sbjct: 124 GLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGTFQA 183 Query: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNP 143 +F +GP GTYRC+GS SPY+ S SDPLLVSVTGNPSNSWPSPTEPSSETGNP Sbjct: 184 DFPLGPATH--GGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSETGNP 241 Query: 144 RHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEV 203 RHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEV Sbjct: 242 RHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEV 301 Query: 204 TYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAEP 243 TYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAEP Sbjct: 302 TYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAEP 341 Score = 258 bits (659), Expect = 3e-69 Identities = 126/144 (87%), Positives = 132/144 (91%), Gaps = 4/144 (2%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL Sbjct: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPL + Sbjct: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120 Query: 121 SVTG---NPS-NSWPSPTEPSSET 140 +TG PS ++ P PT + E+ Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGES 144 >gi|134304833 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 precursor [Homo sapiens] Length = 348 Score = 308 bits (788), Expect = 4e-84 Identities = 155/219 (70%), Positives = 171/219 (78%), Gaps = 3/219 (1%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 G++ KPSL A PGP V + E+V L C S + + L REG+ + G +G +A Sbjct: 124 GLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQA 183 Query: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNP 143 +F +GP GTYRC+GS SPY+ S SDPLLVSVTGNPSNSWPSPTEPSS+TGNP Sbjct: 184 DFPLGPATH--GGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGNP 241 Query: 144 RHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEV 203 RHLH+LIGTSVVIILFILL FFLLHRWC NKKNA VMDQE AGNRT N EDSDEQDPQEV Sbjct: 242 RHLHILIGTSVVIILFILL-FFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEV 300 Query: 204 TYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAE 242 TY QLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAE Sbjct: 301 TYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAE 339 Score = 252 bits (643), Expect = 2e-67 Identities = 123/144 (85%), Positives = 130/144 (90%), Gaps = 4/144 (2%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 MSLMVVSM CVGFFLLQGAWPHEGVHRKPSLLAHPG LVKSEETVILQCWSDVRF+HFLL Sbjct: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60 Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPL + Sbjct: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120 Query: 121 SVTG---NPS-NSWPSPTEPSSET 140 +TG PS ++ P PT + E+ Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGES 144 >gi|134268644 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 precursor [Homo sapiens] Length = 444 Score = 305 bits (781), Expect = 2e-83 Identities = 151/220 (68%), Positives = 172/220 (78%), Gaps = 2/220 (0%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 G + KPSL A PGP V++ E+V L C S + + L REG + + +A Sbjct: 219 GPYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQA 278 Query: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNP 143 +F +GP GTYRC+GS HSPY+ S PSDPLLVSVTGNPS+SWPSPTEPSS++GNP Sbjct: 279 DFPLGPATH--GGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNP 336 Query: 144 RHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEV 203 RHLH+LIGTSVVIILFILLLFFLLH WC NKKNA VMDQEPAGNRT N EDSDEQDP+EV Sbjct: 337 RHLHILIGTSVVIILFILLLFFLLHLWCSNKKNAAVMDQEPAGNRTANSEDSDEQDPEEV 396 Query: 204 TYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAEP 243 TYAQL+HCVFTQRKITRPSQRPKTPPTD I+YTELPNA+P Sbjct: 397 TYAQLDHCVFTQRKITRPSQRPKTPPTDTILYTELPNAKP 436 Score = 168 bits (426), Expect = 3e-42 Identities = 84/121 (69%), Positives = 95/121 (78%), Gaps = 4/121 (3%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 G HRKPSLLAHPGPLVKS E VILQCWSD+ F+HF LH+EG KD L+G+ HDGVSKA Sbjct: 119 GNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKA 178 Query: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTG---NPS-NSWPSPTEPSSE 139 NFSIGPMM LAGTYRCYGSVTH+PYQLSAPSDPL + VTG PS ++ P P + E Sbjct: 179 NFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGE 238 Query: 140 T 140 + Sbjct: 239 S 239 Score = 96.7 bits (239), Expect = 2e-20 Identities = 79/236 (33%), Positives = 112/236 (47%), Gaps = 21/236 (8%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 MSLMVVSM CVG FL+Q A PH G KP L A P +V V L+C RF +F+L Sbjct: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120 ++E D +H I H + + +F++ P+ AG Y C GS HSP SAPS+P+++ Sbjct: 61 YKE----DRIH-IPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVI 115 Query: 121 SVTGNPSNSWPSPTEPSSETGNPRHLHVLIGTSVVIILFILLLF--FLLHRWCCNKKNAV 178 VTGN S +P L V G V++ + ++F F LH+ +K + Sbjct: 116 MVTGN--------HRKPSLLAHPGPL-VKSGERVILQCWSDIMFEHFFLHKEGISKDPSR 166 Query: 179 VMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDIIV 234 ++ Q G N TY T +++ PS P DI+V Sbjct: 167 LVGQIHDGVSKANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSD-----PLDIVV 217 >gi|110611923 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 [Homo sapiens] Length = 348 Score = 302 bits (774), Expect = 2e-82 Identities = 154/219 (70%), Positives = 169/219 (77%), Gaps = 3/219 (1%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 G++ KPSL A GP V + E V L C S + + L REG+ + G +G +A Sbjct: 124 GLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGTFQA 183 Query: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNP 143 +F +GP GTYRC+GS SPY+ S SDPLLVSVTGNPSNSWPSPTEPSS+TGNP Sbjct: 184 DFPLGPATH--GGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGNP 241 Query: 144 RHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEV 203 RHLH+LIGTSVVIILFILL FFLLHRWC NKKNA VMDQE AGNRT N EDSDEQDPQEV Sbjct: 242 RHLHILIGTSVVIILFILL-FFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEV 300 Query: 204 TYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAE 242 TY QLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAE Sbjct: 301 TYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAE 339 Score = 227 bits (579), Expect = 6e-60 Identities = 107/124 (86%), Positives = 112/124 (90%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 MSL+VVSM CVGFFLLQGAWPHEGVHRKPSLLAHPG LVKSEETVILQCWSDV F+HFLL Sbjct: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60 Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120 HREG F DTL LIGEHHDGVSKANFSI M QDLAGTYRCYGSVTHSPYQ+SAPSDPL + Sbjct: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120 Query: 121 SVTG 124 + G Sbjct: 121 VIIG 124 >gi|134268642 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 precursor [Homo sapiens] Length = 455 Score = 278 bits (712), Expect = 2e-75 Identities = 144/220 (65%), Positives = 165/220 (75%), Gaps = 2/220 (0%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 G++ KPSL A PGP V++ E V L C S + + L REG+ + + +A Sbjct: 219 GLYEKPSLSAQPGPTVQAGENVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQA 278 Query: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNP 143 +F +GP GTYRC+GS P S SDPLLVSVTGNPS+SWPSPTEPSS++G Sbjct: 279 DFPLGPATH--GGTYRCFGSFRALPCVWSNSSDPLLVSVTGNPSSSWPSPTEPSSKSGIC 336 Query: 144 RHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEV 203 RHLHVLIGTSVVI LFILLLFFLL+RWC NKKNA VMDQEPAG+RTVNR+DSDEQDPQEV Sbjct: 337 RHLHVLIGTSVVIFLFILLLFFLLYRWCSNKKNAAVMDQEPAGDRTVNRQDSDEQDPQEV 396 Query: 204 TYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAEP 243 TYAQL+HCVF QRKI+RPSQRPKTP TD VYTELPNAEP Sbjct: 397 TYAQLDHCVFIQRKISRPSQRPKTPLTDTSVYTELPNAEP 436 Score = 169 bits (427), Expect = 3e-42 Identities = 84/120 (70%), Positives = 95/120 (79%), Gaps = 4/120 (3%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 G HRKPSLLAHPGPL+KS ETVILQCWSDV F+HF LHREG +D L+G+ HDGVSKA Sbjct: 119 GNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKA 178 Query: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTG---NPS-NSWPSPTEPSSE 139 NFSIGP+M LAGTYRCYGSV HSPYQLSAPSDPL + +TG PS ++ P PT + E Sbjct: 179 NFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGE 238 Score = 103 bits (256), Expect = 2e-22 Identities = 67/144 (46%), Positives = 82/144 (56%), Gaps = 9/144 (6%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 MSL VVSM CVGFFLLQGAWP G KP L A P +V V LQC F +F+L Sbjct: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120 ++E D H + H + + +F +GP+ AGTYRC GS HS SAPS+PL++ Sbjct: 61 YKE----DRSH-VPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVI 115 Query: 121 SVTGN---PS-NSWPSPTEPSSET 140 VTGN PS + P P S ET Sbjct: 116 MVTGNHRKPSLLAHPGPLLKSGET 139 >gi|11968154 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A [Homo sapiens] Length = 375 Score = 271 bits (694), Expect = 3e-73 Identities = 140/220 (63%), Positives = 162/220 (73%), Gaps = 2/220 (0%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 G+ KPSL A PGP V++ E V L C S F + L REG+ + +G +A Sbjct: 119 GLFGKPSLSAQPGPTVRTGENVTLSCSSRSSFDMYHLSREGRAHEPRLPAVPSVNGTFQA 178 Query: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNP 143 +F +GP GTY C+GS+ SPY+ S PSDPLLVSVTGN S+S SPTEPSS+TG Sbjct: 179 DFPLGPATH--GGTYTCFGSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIR 236 Query: 144 RHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEV 203 RHLH+LIGTSV IILFI+L FFLLH C NKKNA VMDQEPAG+RTVNREDSD+QDPQEV Sbjct: 237 RHLHILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQEPAGDRTVNREDSDDQDPQEV 296 Query: 204 TYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAEP 243 TYAQL+HCVFTQ KIT PSQRPKTPPTD +Y ELPNA+P Sbjct: 297 TYAQLDHCVFTQTKITSPSQRPKTPPTDTTMYMELPNAKP 336 Score = 101 bits (251), Expect = 7e-22 Identities = 63/143 (44%), Positives = 82/143 (57%), Gaps = 9/143 (6%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 MSLMV+SM CVGFFLLQGAW HEG KP L A P +V V L C S + F F L Sbjct: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120 ++E + E ++ + + +GP+ AGTYRC GS SP + SAPS+PL++ Sbjct: 61 YKEDGVP-----VPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVI 115 Query: 121 SVT---GNPS-NSWPSPTEPSSE 139 VT G PS ++ P PT + E Sbjct: 116 VVTGLFGKPSLSAQPGPTVRTGE 138 >gi|66267727 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5B precursor [Homo sapiens] Length = 375 Score = 266 bits (681), Expect = 9e-72 Identities = 138/220 (62%), Positives = 159/220 (72%), Gaps = 2/220 (0%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 G+ KPSL A PGP V++ E V L C S F + L REG+ + DG +A Sbjct: 119 GLFGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQA 178 Query: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNP 143 +F +GP GTY C+ S+ SPY+ S PSDPLLVSVTGN S+S SPTEPSS+TG Sbjct: 179 DFPLGPATH--GGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIR 236 Query: 144 RHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEV 203 RHLH+LIGTSV IILFI+L FFLLH C NKKNA VMDQ PAG+RTVNREDSD+QDPQEV Sbjct: 237 RHLHILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQGPAGDRTVNREDSDDQDPQEV 296 Query: 204 TYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAEP 243 TYAQL+HCVFTQ KIT PSQRPK PPTD +Y ELPNA+P Sbjct: 297 TYAQLDHCVFTQTKITSPSQRPKAPPTDTTMYMELPNAKP 336 Score = 101 bits (251), Expect = 7e-22 Identities = 63/143 (44%), Positives = 82/143 (57%), Gaps = 9/143 (6%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 MSLMV+SM CVGFFLLQGAW HEG KP L A P +V V L C S + F F L Sbjct: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120 ++E + E ++ + + +GP+ AGTYRC GS SP + SAPS+PL++ Sbjct: 61 YKEDGVP-----VPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVI 115 Query: 121 SVT---GNPS-NSWPSPTEPSSE 139 VT G PS ++ P PT + E Sbjct: 116 VVTGLFGKPSLSAQPGPTVRTGE 138 >gi|124107606 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 isoform a [Homo sapiens] Length = 377 Score = 265 bits (676), Expect = 4e-71 Identities = 136/220 (61%), Positives = 157/220 (71%), Gaps = 2/220 (0%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 G++ KPSL A PGP V++ E V L C S F + L REG+ + +G +A Sbjct: 121 GLYEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQA 180 Query: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNP 143 +F +GP TYRC+GS SPY+ S PSDPL VSVTGNPS+SWPSPTEPS +TG Sbjct: 181 DFPLGPATH--GETYRCFGSFHGSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKTGIA 238 Query: 144 RHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEV 203 RHLH +I SV IILF +L FFLLHRWC KKNA VM+QEPAG+RTVNREDSDEQDPQEV Sbjct: 239 RHLHAVIRYSVAIILFTILPFFLLHRWCSKKKNAAVMNQEPAGHRTVNREDSDEQDPQEV 298 Query: 204 TYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAEP 243 TYAQL+HC+FTQRKIT PSQR K P TD V ELPNAEP Sbjct: 299 TYAQLDHCIFTQRKITGPSQRSKRPSTDTSVCIELPNAEP 338 Score = 78.6 bits (192), Expect = 5e-15 Identities = 54/143 (37%), Positives = 74/143 (51%), Gaps = 9/143 (6%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 MS V+ + C+GFFL Q W H G KP A P +V V L+C F F L Sbjct: 3 MSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTL 62 Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120 ++ KD + + E ++ + +F I P+ AGTYRC G HSP + SAPS+PL++ Sbjct: 63 YK----KDGVP-VPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVI 117 Query: 121 SVTG---NPS-NSWPSPTEPSSE 139 VTG PS + P PT + E Sbjct: 118 MVTGLYEKPSLTARPGPTVRAGE 140 >gi|6912472 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2 precursor [Homo sapiens] Length = 304 Score = 254 bits (649), Expect = 5e-68 Identities = 123/144 (85%), Positives = 131/144 (90%), Gaps = 4/144 (2%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 MSLMVVSM CVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRF+HFLL Sbjct: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFEHFLL 60 Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120 HREGK+KDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPL + Sbjct: 61 HREGKYKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120 Query: 121 SVTG---NPS-NSWPSPTEPSSET 140 +TG PS ++ P PT + E+ Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGES 144 Score = 233 bits (593), Expect = 1e-61 Identities = 118/183 (64%), Positives = 135/183 (73%), Gaps = 2/183 (1%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 G++ KPSL A PGP V + E+V L C S + + L REG+ + G +G +A Sbjct: 124 GLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGTFQA 183 Query: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNP 143 +F +GP GTYRC+GS SPY+ S SDPLLVSVTGNPSNSWPSPTEPSS+TGNP Sbjct: 184 DFPLGPATH--GGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGNP 241 Query: 144 RHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEV 203 RHLHVLIGTSVV I F +LLFFLLHRWC NKKNA VMDQEPAGNRTVN EDSDEQD QEV Sbjct: 242 RHLHVLIGTSVVKIPFTILLFFLLHRWCSNKKNAAVMDQEPAGNRTVNSEDSDEQDHQEV 301 Query: 204 TYA 206 +YA Sbjct: 302 SYA 304 >gi|46488946 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 [Homo sapiens] Length = 410 Score = 238 bits (606), Expect = 5e-63 Identities = 129/211 (61%), Positives = 143/211 (67%), Gaps = 19/211 (9%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 G++ KPSL A PGP V++ E V L C S F + L RE + + +G +A Sbjct: 219 GLYGKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQA 278 Query: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNP 143 NF +GP+ G YRC+GS P+ S PSDPL VSVTGN Sbjct: 279 NFPLGPVTH--GGNYRCFGSFRALPHAWSDPSDPLPVSVTGNS----------------- 319 Query: 144 RHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEV 203 RHLHVLIGTSVVII F +LLFFLLHRWC NKKNAVVMDQEPAGNRTVNREDSDEQDPQEV Sbjct: 320 RHLHVLIGTSVVIIPFAILLFFLLHRWCANKKNAVVMDQEPAGNRTVNREDSDEQDPQEV 379 Query: 204 TYAQLNHCVFTQRKITRPSQRPKTPPTDIIV 234 TYAQLNHCVFTQRKITRPSQRPKTPPTD V Sbjct: 380 TYAQLNHCVFTQRKITRPSQRPKTPPTDTSV 410 Score = 161 bits (408), Expect = 4e-40 Identities = 80/120 (66%), Positives = 94/120 (78%), Gaps = 4/120 (3%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 GVHRKPSLLAHPGPLVKS ETVILQCWSDVRF+ FLLHREG +D L L+G+ HD S+ Sbjct: 119 GVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQV 178 Query: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPL---LVSVTGNPS-NSWPSPTEPSSE 139 N+S+GPM LAGTYRC+GSVTH PY+LSAPSDPL +V + G PS ++ P PT + E Sbjct: 179 NYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGE 238 Score = 108 bits (270), Expect = 4e-24 Identities = 65/144 (45%), Positives = 83/144 (57%), Gaps = 9/144 (6%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 MSLMVVSM CVGFFLL+G WPH G KP L A PG +V + V LQC S + F F L Sbjct: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60 Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120 +E + E ++ + + +F +GP+ AGTYRC S HSP SAPS+P+++ Sbjct: 61 SKEDGMP-----VPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVI 115 Query: 121 SVTG---NPS-NSWPSPTEPSSET 140 VTG PS + P P S ET Sbjct: 116 MVTGVHRKPSLLAHPGPLVKSGET 139 >gi|7657277 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 precursor [Homo sapiens] Length = 304 Score = 233 bits (594), Expect = 1e-61 Identities = 119/183 (65%), Positives = 134/183 (73%), Gaps = 2/183 (1%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 G++ KPSL A PGP V + E V L C S + + L REG+ + G +G +A Sbjct: 124 GLYEKPSLSAQPGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGTKVNGTFQA 183 Query: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNP 143 NF +GP GTYRC+GS SPY+ S SDPLLVSVTGNPSNSWPSPTEPSSETGNP Sbjct: 184 NFPLGPATH--GGTYRCFGSFRDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSETGNP 241 Query: 144 RHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEV 203 RHLHVLIGTSVV I F +LLFFLLHRWC +KKNA VMDQEPAGNRTVN EDSDEQD QEV Sbjct: 242 RHLHVLIGTSVVKIPFTILLFFLLHRWCSDKKNAAVMDQEPAGNRTVNSEDSDEQDHQEV 301 Query: 204 TYA 206 +YA Sbjct: 302 SYA 304 Score = 229 bits (584), Expect = 2e-60 Identities = 114/143 (79%), Positives = 120/143 (83%), Gaps = 4/143 (2%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 MSL VVSM CVGFFLLQGAWPHEGVHRKPSLLAHPG LVKSEETVILQCWSDV F+HFLL Sbjct: 1 MSLTVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60 Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120 HREG F DTL LIGEHHDGVSKANFSI M QDLAGTYRCYGSVTHSPYQLSAPSDPL + Sbjct: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMKQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120 Query: 121 SVTG---NPS-NSWPSPTEPSSE 139 + G PS ++ P PT + E Sbjct: 121 VIIGLYEKPSLSAQPGPTVLAGE 143 >gi|6912474 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3 [Homo sapiens] Length = 304 Score = 228 bits (580), Expect = 5e-60 Identities = 116/183 (63%), Positives = 135/183 (73%), Gaps = 2/183 (1%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 G++ KPSL A PGP V + E+V L C S + + L EG+ + G +G +A Sbjct: 124 GLYEKPSLSAQPGPTVLAGESVTLSCSSWSSYDMYHLSTEGEAHERRFSAGPKVNGTFQA 183 Query: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNP 143 +F +GP Q GTYRC+GS SPY+ S SDPLLVSVTGNPSNSWPSPTEPSS+TGNP Sbjct: 184 DFPLGPATQ--GGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGNP 241 Query: 144 RHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEV 203 RHLHVLIGTSVV + F +LLFFLLHRWC +KKNA VMDQ PAGNRTVNREDSDEQD QEV Sbjct: 242 RHLHVLIGTSVVKLPFTILLFFLLHRWCSDKKNASVMDQGPAGNRTVNREDSDEQDHQEV 301 Query: 204 TYA 206 +YA Sbjct: 302 SYA 304 Score = 221 bits (562), Expect = 6e-58 Identities = 110/144 (76%), Positives = 118/144 (81%), Gaps = 4/144 (2%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 MSLMV+SM CVGFF LQGAWPHEG RKPSLLAHPG LVKSEETVILQCWSDV F+HFLL Sbjct: 1 MSLMVISMACVGFFWLQGAWPHEGFRRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60 Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120 HREG F DTL LIGEH DGVSKANFSIG M QDLAGTYRCYGSV HSPYQ SAPSDPL + Sbjct: 61 HREGTFNDTLRLIGEHIDGVSKANFSIGRMRQDLAGTYRCYGSVPHSPYQFSAPSDPLDI 120 Query: 121 SVTG---NPS-NSWPSPTEPSSET 140 +TG PS ++ P PT + E+ Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGES 144 >gi|116517309 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4 [Homo sapiens] Length = 304 Score = 226 bits (576), Expect = 1e-59 Identities = 115/183 (62%), Positives = 134/183 (73%), Gaps = 2/183 (1%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 G++ KPSL A PGP V++ E V L C S + + L REG+ + +G +A Sbjct: 124 GLYEKPSLSAQPGPTVQAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAVRSINGTFQA 183 Query: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNP 143 +F +GP GTYRC+GS +PY+ S SDPLLVSVTGNPSNSWPSPTEPSS+TGNP Sbjct: 184 DFPLGPATH--GGTYRCFGSFRDAPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGNP 241 Query: 144 RHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEV 203 RHLHVLIGTSVV I F +LLFFLLHRWC +KKNA VMDQEPAGNRTVN EDSDEQD QEV Sbjct: 242 RHLHVLIGTSVVKIPFTILLFFLLHRWCSDKKNAAVMDQEPAGNRTVNSEDSDEQDHQEV 301 Query: 204 TYA 206 +YA Sbjct: 302 SYA 304 Score = 223 bits (569), Expect = 9e-59 Identities = 111/143 (77%), Positives = 119/143 (83%), Gaps = 4/143 (2%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 MSLMV+ M CVGFFLLQGAWP EGVHRKPS LA PG LVKSEETVILQCWSDV F+HFLL Sbjct: 1 MSLMVIIMACVGFFLLQGAWPQEGVHRKPSFLALPGHLVKSEETVILQCWSDVMFEHFLL 60 Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120 HREGKF +TLHLIGEHHDGVSKANFSIGPMM LAGTYRCYGSV HSPYQLSAPSDPL + Sbjct: 61 HREGKFNNTLHLIGEHHDGVSKANFSIGPMMPVLAGTYRCYGSVPHSPYQLSAPSDPLDM 120 Query: 121 SVTG---NPS-NSWPSPTEPSSE 139 + G PS ++ P PT + E Sbjct: 121 VIIGLYEKPSLSAQPGPTVQAGE 143 >gi|134304835 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5 [Homo sapiens] Length = 304 Score = 224 bits (570), Expect = 7e-59 Identities = 111/144 (77%), Positives = 119/144 (82%), Gaps = 4/144 (2%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 MSLMV+SM CV FFLLQGAWPHEG RKPSLLAHPGPLVKSEETVILQCWSDV F+HFLL Sbjct: 1 MSLMVISMACVAFFLLQGAWPHEGFRRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLL 60 Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120 HREG F TL LIGEH DGVSK NFSIG M QDLAGTYRCYGSVTHSPYQLSAPSDPL + Sbjct: 61 HREGTFNHTLRLIGEHIDGVSKGNFSIGRMTQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120 Query: 121 SVTG---NPS-NSWPSPTEPSSET 140 +TG PS ++ P PT + E+ Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGES 144 Score = 223 bits (567), Expect = 2e-58 Identities = 115/183 (62%), Positives = 132/183 (72%), Gaps = 2/183 (1%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 G++ KPSL A PGP V + E+V L C S + + L REG+ + G + +A Sbjct: 124 GLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNRTFQA 183 Query: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNP 143 +F + P GTYRC+GS SPY+ S SDPLLVSVTGN SNSWPSPTEPSSETGNP Sbjct: 184 DFPLDPATH--GGTYRCFGSFRDSPYEWSKSSDPLLVSVTGNSSNSWPSPTEPSSETGNP 241 Query: 144 RHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEV 203 RHLHVLIGTSVV + F +LLFFLLHRWC NKKNA VMDQ PAGNRTVNREDSDEQD QEV Sbjct: 242 RHLHVLIGTSVVKLPFTILLFFLLHRWCSNKKNASVMDQGPAGNRTVNREDSDEQDHQEV 301 Query: 204 TYA 206 +YA Sbjct: 302 SYA 304 >gi|124107610 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 isoform c [Homo sapiens] Length = 342 Score = 199 bits (507), Expect = 1e-51 Identities = 112/220 (50%), Positives = 132/220 (60%), Gaps = 37/220 (16%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 G++ KPSL A PGP V++ E V L C S F + L REG+ + +G +A Sbjct: 121 GLYEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQA 180 Query: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNP 143 +F +GP TYRC+GS SPY+ S PSDPL VSVTGNPS+SWPSPTEPS +T Sbjct: 181 DFPLGPATH--GETYRCFGSFHGSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKT--- 235 Query: 144 RHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEV 203 +A VM+QEPAG+RTVNREDSDEQDPQEV Sbjct: 236 --------------------------------DAAVMNQEPAGHRTVNREDSDEQDPQEV 263 Query: 204 TYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAEP 243 TYAQL+HC+FTQRKIT PSQR K P TD V ELPNAEP Sbjct: 264 TYAQLDHCIFTQRKITGPSQRSKRPSTDTSVCIELPNAEP 303 Score = 78.6 bits (192), Expect = 5e-15 Identities = 54/143 (37%), Positives = 74/143 (51%), Gaps = 9/143 (6%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 MS V+ + C+GFFL Q W H G KP A P +V V L+C F F L Sbjct: 3 MSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTL 62 Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120 ++ KD + + E ++ + +F I P+ AGTYRC G HSP + SAPS+PL++ Sbjct: 63 YK----KDGVP-VPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVI 117 Query: 121 SVTG---NPS-NSWPSPTEPSSE 139 VTG PS + P PT + E Sbjct: 118 MVTGLYEKPSLTARPGPTVRAGE 140 >gi|62632748 killer-cell Ig-like receptor [Homo sapiens] Length = 328 Score = 186 bits (471), Expect = 2e-47 Identities = 93/121 (76%), Positives = 100/121 (82%), Gaps = 4/121 (3%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 GVHRKPSLLAHPGPLVKSEETVILQCWSDV F+HFLLHREGKF DTL L GE HDGVSKA Sbjct: 119 GVHRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLLHREGKFNDTLRLTGELHDGVSKA 178 Query: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVT---GNPS-NSWPSPTEPSSE 139 NFSIG M QDLAGTYRCYGSV HSPYQLSAPSDPL + +T G PS ++ P P + E Sbjct: 179 NFSIGRMTQDLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLCGKPSLSAQPRPMVKAGE 238 Query: 140 T 140 + Sbjct: 239 S 239 Score = 108 bits (270), Expect = 4e-24 Identities = 68/144 (47%), Positives = 81/144 (56%), Gaps = 9/144 (6%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 MSLMV+SM CVGFFLLQGAW HEG KP L A P P+V E V LQC S + F F L Sbjct: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPFLSAWPSPVVSEGEHVALQCRSRLGFNEFSL 60 Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120 +E + E ++ V + IGP+ AGTYRC GS H SAPS+PL++ Sbjct: 61 SKEDGMP-----VPELYNRVFRNTVFIGPVTPAHAGTYRCRGSHPHFLTGWSAPSNPLVI 115 Query: 121 SVTG---NPS-NSWPSPTEPSSET 140 VTG PS + P P S ET Sbjct: 116 MVTGVHRKPSLLAHPGPLVKSEET 139 Score = 77.4 bits (189), Expect = 1e-14 Identities = 45/100 (45%), Positives = 58/100 (58%), Gaps = 2/100 (2%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 G+ KPSL A P P+VK+ E+V L C S + + L REG+ + +G +A Sbjct: 219 GLCGKPSLSAQPRPMVKAGESVTLSCSSRSSYDIYHLSREGEAHELRFPAVPKVNGTFQA 278 Query: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVT 123 NF +GP GTYRC+GS SPY+ S SDPLLVSVT Sbjct: 279 NFPLGPATH--GGTYRCFGSFRDSPYEWSDLSDPLLVSVT 316 >gi|134133244 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1 [Homo sapiens] Length = 382 Score = 171 bits (432), Expect = 7e-43 Identities = 87/152 (57%), Positives = 106/152 (69%), Gaps = 2/152 (1%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 G++ KPSL A PGP V++ E+V L C S + + L REG + + +A Sbjct: 219 GLYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQA 278 Query: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNP 143 +F +GP GTYRC+GS HSPY+ S PSDPLLVSVTGNPS+SWPSPTEPSS++GN Sbjct: 279 DFPLGPATH--GGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNL 336 Query: 144 RHLHVLIGTSVVIILFILLLFFLLHRWCCNKK 175 RHLH+LIGTSVV I F +LLFFLLHRWC NKK Sbjct: 337 RHLHILIGTSVVKIPFTILLFFLLHRWCSNKK 368 Score = 163 bits (413), Expect = 1e-40 Identities = 82/121 (67%), Positives = 94/121 (77%), Gaps = 4/121 (3%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 G HRKPSLLAHPGPLVKS E VILQCWSD+ F+HF LH+E KD L+G+ HDGVSKA Sbjct: 119 GNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKA 178 Query: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTG---NPS-NSWPSPTEPSSE 139 NFSIG MM+ LAGTYRCYGSVTH+PYQLSAPSDPL + VTG PS ++ P P + E Sbjct: 179 NFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGE 238 Query: 140 T 140 + Sbjct: 239 S 239 Score = 95.5 bits (236), Expect = 4e-20 Identities = 77/236 (32%), Positives = 110/236 (46%), Gaps = 21/236 (8%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 M LMVVSM CVG FL+Q A PH G KP L A P +V V L+C RF +F+L Sbjct: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120 ++E D +H + H + + F++ P+ AG Y C GS HSP SAPS+P+++ Sbjct: 61 YKE----DRIH-VPIFHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVI 115 Query: 121 SVTGNPSNSWPSPTEPSSETGNPRHLHVLIGTSVVIILFILLLF--FLLHRWCCNKKNAV 178 VTGN S +P L V G V++ + ++F F LH+ +K + Sbjct: 116 MVTGN--------HRKPSLLAHPGPL-VKSGERVILQCWSDIMFEHFFLHKEWISKDPSR 166 Query: 179 VMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDIIV 234 ++ Q G N TY T +++ PS P DI+V Sbjct: 167 LVGQIHDGVSKANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSD-----PLDIVV 217 >gi|124107604 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 isoform b [Homo sapiens] Length = 273 Score = 154 bits (389), Expect = 7e-38 Identities = 81/152 (53%), Positives = 98/152 (64%), Gaps = 2/152 (1%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 G++ KPSL A PGP V++ E V L C S F + L REG+ + +G +A Sbjct: 121 GLYEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQA 180 Query: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNP 143 +F +GP TYRC+GS SPY+ S PSDPL VSVTGNPS+SWPSPTEPS +TG Sbjct: 181 DFPLGPATH--GETYRCFGSFHGSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKTGIA 238 Query: 144 RHLHVLIGTSVVIILFILLLFFLLHRWCCNKK 175 RHLH +I SV IILF +L FFLLHRWC KK Sbjct: 239 RHLHAVIRYSVAIILFTILPFFLLHRWCSKKK 270 Score = 78.6 bits (192), Expect = 5e-15 Identities = 54/143 (37%), Positives = 74/143 (51%), Gaps = 9/143 (6%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 MS V+ + C+GFFL Q W H G KP A P +V V L+C F F L Sbjct: 3 MSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTL 62 Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120 ++ KD + + E ++ + +F I P+ AGTYRC G HSP + SAPS+PL++ Sbjct: 63 YK----KDGVP-VPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVI 117 Query: 121 SVTG---NPS-NSWPSPTEPSSE 139 VTG PS + P PT + E Sbjct: 118 MVTGLYEKPSLTARPGPTVRAGE 140 >gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B, member 3 isoform 2 [Homo sapiens] Length = 631 Score = 111 bits (277), Expect = 6e-25 Identities = 80/229 (34%), Positives = 107/229 (46%), Gaps = 18/229 (7%) Query: 30 SLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGP 89 SL A PGP V S E V L C S +F FLL +EG L L + +A F + P Sbjct: 326 SLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSP 385 Query: 90 MMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNPRHLHVL 149 + AGTYRCYGS + +P+ LS PS+PL + V+G+ S PT P S G R+L VL Sbjct: 386 VTSAHAGTYRCYGSYSSNPHLLSHPSEPLELVVSGHSGGSSLPPTGPPSTPGLGRYLEVL 445 Query: 150 IGTSVVIILFILLLFFLL--------HRWCCNKKNAVVMDQEPAG-------NRTVNRED 194 IG SV +L + LL FLL HR +K Q PAG +R + R Sbjct: 446 IGVSVAFVLLLFLLLFLLLRRQRHSKHRTSDQRKTDF---QRPAGAAETEPKDRGLLRRS 502 Query: 195 SDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAEP 243 S D QE ++ ++ SQ P + Y + ++ P Sbjct: 503 SPAADVQEENLYAAVKDTQSEDRVELDSQSPHDEDPQAVTYAPVKHSSP 551 Score = 83.6 bits (205), Expect = 1e-16 Identities = 50/122 (40%), Positives = 73/122 (59%), Gaps = 8/122 (6%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHD-GVSK 82 GV RKPSLL GP++ +++ LQC SDV + F+L++EG+ +D L G+ G+S+ Sbjct: 220 GVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGE-RDFLQRPGQQPQAGLSQ 278 Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGN-----PSNSWPSPTEPS 137 ANF++GP+ G YRCYG+ S + SAPSDPL + + G ++ P PT S Sbjct: 279 ANFTLGPVSPSNGGQYRCYGAHNLSS-EWSAPSDPLNILMAGQIYDTVSLSAQPGPTVAS 337 Query: 138 SE 139 E Sbjct: 338 GE 339 Score = 59.3 bits (142), Expect = 3e-09 Identities = 34/102 (33%), Positives = 54/102 (52%), Gaps = 1/102 (0%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEH-HDGVSK 82 G + KP+L A P P+V S + L+C S + HF+L +EG+ + L + H + Sbjct: 119 GAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQ 178 Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTG 124 A F +GP+ + CY T++P+ S PSDPL + +G Sbjct: 179 ALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSG 220 Score = 54.7 bits (130), Expect = 7e-08 Identities = 43/141 (30%), Positives = 65/141 (46%), Gaps = 9/141 (6%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 M+ + +++C+G L G KP+L A PG ++ V + C Q + L Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRL 60 Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120 H+EG + + +KA FSI M + AG YRC+ +S S PSDPL + Sbjct: 61 HKEGSPEPLDR--NNPLEPKNKARFSIPSMTEHHAGRYRCH---YYSSAGWSEPSDPLEM 115 Query: 121 SVTGNPS----NSWPSPTEPS 137 +TG S ++ PSP S Sbjct: 116 VMTGAYSKPTLSALPSPVVAS 136 Score = 31.6 bits (70), Expect = 0.65 Identities = 15/58 (25%), Positives = 29/58 (50%) Query: 181 DQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTEL 238 D++ +R ++ E + + Q+VTYAQL+ ++ P + PP + +Y L Sbjct: 571 DRQVEEDRQMDTEAAASEASQDVTYAQLHSLTLRRKATEPPPSQEGEPPAEPSIYATL 628 >gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B, member 3 isoform 1 [Homo sapiens] Length = 632 Score = 110 bits (274), Expect = 1e-24 Identities = 82/230 (35%), Positives = 106/230 (46%), Gaps = 19/230 (8%) Query: 30 SLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGP 89 SL A PGP V S E V L C S +F FLL +EG L L + +A F + P Sbjct: 326 SLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSP 385 Query: 90 MMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNPRHLHVL 149 + AGTYRCYGS + +P+ LS PS+PL + V+G+ S PT P S G R+L VL Sbjct: 386 VTSAHAGTYRCYGSYSSNPHLLSHPSEPLELVVSGHSGGSSLPPTGPPSTPGLGRYLEVL 445 Query: 150 IGTSVVIILFILLLFFLL--------HRWCCNKKNAVVMDQEPAG-------NRTVNRED 194 IG SV +L + LL FLL HR +K Q PAG +R + R Sbjct: 446 IGVSVAFVLLLFLLLFLLLRRQRHSKHRTSDQRKTDF---QRPAGAAETEPKDRGLLRRS 502 Query: 195 SDEQDPQEVT-YAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAEP 243 S D QE YA + R Q P + Y + ++ P Sbjct: 503 SPAADVQEENLYAAVKDTQSEDRVELDSQQSPHDEDPQAVTYAPVKHSSP 552 Score = 83.6 bits (205), Expect = 1e-16 Identities = 50/122 (40%), Positives = 73/122 (59%), Gaps = 8/122 (6%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHD-GVSK 82 GV RKPSLL GP++ +++ LQC SDV + F+L++EG+ +D L G+ G+S+ Sbjct: 220 GVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGE-RDFLQRPGQQPQAGLSQ 278 Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGN-----PSNSWPSPTEPS 137 ANF++GP+ G YRCYG+ S + SAPSDPL + + G ++ P PT S Sbjct: 279 ANFTLGPVSPSNGGQYRCYGAHNLSS-EWSAPSDPLNILMAGQIYDTVSLSAQPGPTVAS 337 Query: 138 SE 139 E Sbjct: 338 GE 339 Score = 59.3 bits (142), Expect = 3e-09 Identities = 34/102 (33%), Positives = 54/102 (52%), Gaps = 1/102 (0%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEH-HDGVSK 82 G + KP+L A P P+V S + L+C S + HF+L +EG+ + L + H + Sbjct: 119 GAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQ 178 Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTG 124 A F +GP+ + CY T++P+ S PSDPL + +G Sbjct: 179 ALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSG 220 Score = 54.7 bits (130), Expect = 7e-08 Identities = 43/141 (30%), Positives = 65/141 (46%), Gaps = 9/141 (6%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 M+ + +++C+G L G KP+L A PG ++ V + C Q + L Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRL 60 Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120 H+EG + + +KA FSI M + AG YRC+ +S S PSDPL + Sbjct: 61 HKEGSPEPLDR--NNPLEPKNKARFSIPSMTEHHAGRYRCH---YYSSAGWSEPSDPLEM 115 Query: 121 SVTGNPS----NSWPSPTEPS 137 +TG S ++ PSP S Sbjct: 116 VMTGAYSKPTLSALPSPVVAS 136 Score = 31.6 bits (70), Expect = 0.65 Identities = 15/58 (25%), Positives = 29/58 (50%) Query: 181 DQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTEL 238 D++ +R ++ E + + Q+VTYAQL+ ++ P + PP + +Y L Sbjct: 572 DRQVEEDRQMDTEAAASEASQDVTYAQLHSLTLRRKATEPPPSQEGEPPAEPSIYATL 629 >gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B, member 2 isoform 1 [Homo sapiens] Length = 598 Score = 107 bits (268), Expect = 7e-24 Identities = 81/271 (29%), Positives = 112/271 (41%), Gaps = 61/271 (22%) Query: 29 PSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKANFSIG 88 P + PGP V S E V L C S +F FLL + G L L H +A F + Sbjct: 325 PFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMS 384 Query: 89 PMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNP----- 143 P+ AGTYRCYGS+ PY LS PS+PL + V+G S P PT P S P Sbjct: 385 PVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELVVSGPSMGSSPPPTGPISTPAGPEDQPL 444 Query: 144 ------------RHLHVLIG--TSVVIILFILLLFFLLHR-------WCCNKKN------ 176 RHL V+IG +VV++L +LLL FL+ R W ++ Sbjct: 445 TPTGSDPQSGLGRHLGVVIGILVAVVLLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHP 504 Query: 177 -----------------------------AVVMDQEPAGNRTVNREDSDEQDPQEVTYAQ 207 A V D +P ++ + + PQ+VTYAQ Sbjct: 505 AGAVGPEPTDRGLQWRSSPAADAQEENLYAAVKDTQPEDGVEMDTRAAASEAPQDVTYAQ 564 Query: 208 LNHCVFTQRKITRPSQRPKTPPTDIIVYTEL 238 L+ ++ P + + PP + +Y L Sbjct: 565 LHSLTLRRKATEPPPSQEREPPAEPSIYATL 595 Score = 89.4 bits (220), Expect = 3e-18 Identities = 52/122 (42%), Positives = 74/122 (60%), Gaps = 8/122 (6%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIG-EHHDGVSK 82 GV +KPSL PGP+V E++ LQC SDV + F+L++EG+ +D L G + G+S+ Sbjct: 220 GVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVLYKEGE-RDLRQLPGRQPQAGLSQ 278 Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNS-----WPSPTEPS 137 ANF++GP+ + G YRCYG+ S + SAPSDPL + +TG + P PT S Sbjct: 279 ANFTLGPVSRSYGGQYRCYGAHNLSS-ECSAPSDPLDILITGQIRGTPFISVQPGPTVAS 337 Query: 138 SE 139 E Sbjct: 338 GE 339 Score = 72.8 bits (177), Expect = 3e-13 Identities = 43/102 (42%), Positives = 60/102 (58%), Gaps = 1/102 (0%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHD-GVSK 82 G + KP+L A P P+V S V LQC S V F F+L +EG+ + L + H G S+ Sbjct: 119 GAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSR 178 Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTG 124 A FS+GP+ + ++RCYG +SPY S+PSD L + V G Sbjct: 179 AIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPG 220 Score = 47.0 bits (110), Expect = 2e-05 Identities = 37/134 (27%), Positives = 59/134 (44%), Gaps = 9/134 (6%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 M+ +V ++C+G L G KP+L A P ++ V L C + Q + L Sbjct: 1 MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRL 60 Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120 +RE K + I + V F I + + G Y C +S + S SDPL++ Sbjct: 61 YREKKSASWITRI--RPELVKNGQFHIPSITWEHTGRYGCQ---YYSRARWSELSDPLVL 115 Query: 121 SVTGNPSNSWPSPT 134 +TG ++P PT Sbjct: 116 VMTG----AYPKPT 125 >gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B, member 2 isoform 2 [Homo sapiens] Length = 597 Score = 107 bits (268), Expect = 7e-24 Identities = 81/270 (30%), Positives = 114/270 (42%), Gaps = 60/270 (22%) Query: 29 PSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKANFSIG 88 P + PGP V S E V L C S +F FLL + G L L H +A F + Sbjct: 325 PFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMS 384 Query: 89 PMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSS---------- 138 P+ AGTYRCYGS+ PY LS PS+PL + V+G S P PT P S Sbjct: 385 PVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELVVSGPSMGSSPPPTGPISTPGPEDQPLT 444 Query: 139 ------ETGNPRHLHVLIG--TSVVIILFILLLFFLLHR-------WCCNKKN------- 176 ++G RHL V+IG +VV++L +LLL FL+ R W ++ Sbjct: 445 PTGSDPQSGLGRHLGVVIGILVAVVLLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPA 504 Query: 177 ----------------------------AVVMDQEPAGNRTVNREDSDEQDPQEVTYAQL 208 A V D +P ++ + + PQ+VTYAQL Sbjct: 505 GAVGPEPTDRGLQWRSSPAADAQEENLYAAVKDTQPEDGVEMDTRAAASEAPQDVTYAQL 564 Query: 209 NHCVFTQRKITRPSQRPKTPPTDIIVYTEL 238 + ++ P + + PP + +Y L Sbjct: 565 HSLTLRRKATEPPPSQEREPPAEPSIYATL 594 Score = 89.4 bits (220), Expect = 3e-18 Identities = 52/122 (42%), Positives = 74/122 (60%), Gaps = 8/122 (6%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIG-EHHDGVSK 82 GV +KPSL PGP+V E++ LQC SDV + F+L++EG+ +D L G + G+S+ Sbjct: 220 GVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVLYKEGE-RDLRQLPGRQPQAGLSQ 278 Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNS-----WPSPTEPS 137 ANF++GP+ + G YRCYG+ S + SAPSDPL + +TG + P PT S Sbjct: 279 ANFTLGPVSRSYGGQYRCYGAHNLSS-ECSAPSDPLDILITGQIRGTPFISVQPGPTVAS 337 Query: 138 SE 139 E Sbjct: 338 GE 339 Score = 72.8 bits (177), Expect = 3e-13 Identities = 43/102 (42%), Positives = 60/102 (58%), Gaps = 1/102 (0%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHD-GVSK 82 G + KP+L A P P+V S V LQC S V F F+L +EG+ + L + H G S+ Sbjct: 119 GAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSR 178 Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTG 124 A FS+GP+ + ++RCYG +SPY S+PSD L + V G Sbjct: 179 AIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPG 220 Score = 47.0 bits (110), Expect = 2e-05 Identities = 37/134 (27%), Positives = 59/134 (44%), Gaps = 9/134 (6%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 M+ +V ++C+G L G KP+L A P ++ V L C + Q + L Sbjct: 1 MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRL 60 Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120 +RE K + I + V F I + + G Y C +S + S SDPL++ Sbjct: 61 YREKKSASWITRI--RPELVKNGQFHIPSITWEHTGRYGCQ---YYSRARWSELSDPLVL 115 Query: 121 SVTGNPSNSWPSPT 134 +TG ++P PT Sbjct: 116 VMTG----AYPKPT 125 >gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B, member 1 isoform 4 [Homo sapiens] Length = 651 Score = 103 bits (257), Expect = 1e-22 Identities = 83/248 (33%), Positives = 109/248 (43%), Gaps = 37/248 (14%) Query: 30 SLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGP 89 SL PGP V S E V L C S Q FLL +EG D L + +A F +GP Sbjct: 327 SLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGP 386 Query: 90 MMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNP------ 143 + AGTYRCYGS + PY L+ PSDPL + V+G PS SPT + T P Sbjct: 387 VTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSG-PSGGPSSPTTGPTSTSGPEDQPLT 445 Query: 144 -----------RHLHVLIG--TSVVIILFILLLFFLLHR-------WCCNKKNAVVMDQE 183 RHL V+IG +V+++L +LLL FL+ R W ++ A Q Sbjct: 446 PTGSDPQSGLGRHLGVVIGILVAVILLLLLLLLLFLILRHRRQGKHWTSTQRKADF--QH 503 Query: 184 PAG-------NRTVNREDSDEQDPQEVT-YAQLNHCVFTQRKITRPSQRPKTPPTDIIVY 235 PAG +R + S D QE YA + H Q P + Y Sbjct: 504 PAGAVGPEPTDRGLQWRSSPAADAQEENLYAAVKHTQPEDGVEMDTRQSPHDEDPQAVTY 563 Query: 236 TELPNAEP 243 E+ ++ P Sbjct: 564 AEVKHSRP 571 Score = 91.7 bits (226), Expect = 5e-19 Identities = 52/122 (42%), Positives = 74/122 (60%), Gaps = 8/122 (6%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIG-EHHDGVSK 82 GV +KPSL PGP+V EET+ LQC SD + F+L+++G+ +D L L G + G+S+ Sbjct: 221 GVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGE-RDFLQLAGAQPQAGLSQ 279 Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGN-----PSNSWPSPTEPS 137 ANF++GP+ + G YRCYG+ S + SAPSDPL + + G + P PT S Sbjct: 280 ANFTLGPVSRSYGGQYRCYGAHNLSS-EWSAPSDPLDILIAGQFYDRVSLSVQPGPTVAS 338 Query: 138 SE 139 E Sbjct: 339 GE 340 Score = 74.7 bits (182), Expect = 7e-14 Identities = 50/122 (40%), Positives = 66/122 (54%), Gaps = 5/122 (4%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHD-GVSK 82 G + KP+L A P P+V S VILQC S V F F L +EG+ + L + H G S+ Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179 Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSD---PLLVSVTGNPSNS-WPSPTEPSS 138 A FS+GP+ YRCY ++SPY+ S PSD L++ V+ PS S P P Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239 Query: 139 ET 140 ET Sbjct: 240 ET 241 Score = 52.0 bits (123), Expect = 5e-07 Identities = 41/125 (32%), Positives = 58/125 (46%), Gaps = 6/125 (4%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 M+ ++ ++C+G L G KP+L A PG ++ V L+C Q + L Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60 Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRC-YGSVTHSPYQLSAPSDPLL 119 +RE K L + + V K F I + + AG YRC YGS T S SDPL Sbjct: 61 YREK--KTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAG---RSESSDPLE 115 Query: 120 VSVTG 124 + VTG Sbjct: 116 LVVTG 120 Score = 31.6 bits (70), Expect = 0.65 Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 3/58 (5%) Query: 181 DQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITR--PSQRPKTPPTDIIVYT 236 D++ +R ++ E + + PQ+VTYAQL H + +R+ T PSQ +P I T Sbjct: 591 DRQAEEDRQMDTEAAASEAPQDVTYAQL-HSLTLRREATEPPPSQEGPSPAVPSIYAT 647 >gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B, member 1 isoform 1 [Homo sapiens] Length = 650 Score = 103 bits (256), Expect = 2e-22 Identities = 82/248 (33%), Positives = 112/248 (45%), Gaps = 38/248 (15%) Query: 30 SLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGP 89 SL PGP V S E V L C S Q FLL +EG D L + +A F +GP Sbjct: 327 SLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGP 386 Query: 90 MMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNP------ 143 + AGTYRCYGS + PY L+ PSDPL + V+G PS SPT + T P Sbjct: 387 VTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSG-PSGGPSSPTTGPTSTSGPEDQPLT 445 Query: 144 -----------RHLHVLIG--TSVVIILFILLLFFLLHR-------WCCNKKNAVVMDQE 183 RHL V+IG +V+++L +LLL FL+ R W ++ A Q Sbjct: 446 PTGSDPQSGLGRHLGVVIGILVAVILLLLLLLLLFLILRHRRQGKHWTSTQRKADF--QH 503 Query: 184 PAG-------NRTVNREDSDEQDPQEVT-YAQLNHCVFTQRKITRPSQRPKTPPTDIIVY 235 PAG +R + S D QE YA + H + + ++ P + Y Sbjct: 504 PAGAVGPEPTDRGLQWRSSPAADAQEENLYAAVKH-TQPEDGVEMDTRSPHDEDPQAVTY 562 Query: 236 TELPNAEP 243 E+ ++ P Sbjct: 563 AEVKHSRP 570 Score = 91.7 bits (226), Expect = 5e-19 Identities = 52/122 (42%), Positives = 74/122 (60%), Gaps = 8/122 (6%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIG-EHHDGVSK 82 GV +KPSL PGP+V EET+ LQC SD + F+L+++G+ +D L L G + G+S+ Sbjct: 221 GVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGE-RDFLQLAGAQPQAGLSQ 279 Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGN-----PSNSWPSPTEPS 137 ANF++GP+ + G YRCYG+ S + SAPSDPL + + G + P PT S Sbjct: 280 ANFTLGPVSRSYGGQYRCYGAHNLSS-EWSAPSDPLDILIAGQFYDRVSLSVQPGPTVAS 338 Query: 138 SE 139 E Sbjct: 339 GE 340 Score = 74.7 bits (182), Expect = 7e-14 Identities = 50/122 (40%), Positives = 66/122 (54%), Gaps = 5/122 (4%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHD-GVSK 82 G + KP+L A P P+V S VILQC S V F F L +EG+ + L + H G S+ Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179 Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSD---PLLVSVTGNPSNS-WPSPTEPSS 138 A FS+GP+ YRCY ++SPY+ S PSD L++ V+ PS S P P Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239 Query: 139 ET 140 ET Sbjct: 240 ET 241 Score = 52.0 bits (123), Expect = 5e-07 Identities = 41/125 (32%), Positives = 58/125 (46%), Gaps = 6/125 (4%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 M+ ++ ++C+G L G KP+L A PG ++ V L+C Q + L Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60 Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRC-YGSVTHSPYQLSAPSDPLL 119 +RE K L + + V K F I + + AG YRC YGS T S SDPL Sbjct: 61 YREK--KTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAG---RSESSDPLE 115 Query: 120 VSVTG 124 + VTG Sbjct: 116 LVVTG 120 Score = 31.6 bits (70), Expect = 0.65 Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 3/58 (5%) Query: 181 DQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITR--PSQRPKTPPTDIIVYT 236 D++ +R ++ E + + PQ+VTYAQL H + +R+ T PSQ +P I T Sbjct: 590 DRQAEEDRQMDTEAAASEAPQDVTYAQL-HSLTLRREATEPPPSQEGPSPAVPSIYAT 646 >gi|125987588 leukocyte immunoglobulin-like receptor, subfamily B, member 4 isoform 2 [Homo sapiens] Length = 447 Score = 102 bits (255), Expect = 2e-22 Identities = 82/268 (30%), Positives = 109/268 (40%), Gaps = 67/268 (25%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 G + KP+L A P PLV S ++V L C S FLL +E LHL EH +A Sbjct: 119 GAYSKPTLSALPSPLVTSGKSVTLLCQSRSPMDTFLLIKERAAHPLLHLRSEHGAQQHQA 178 Query: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNP 143 F + P+ GTYRC+ S S Y LS PSDPL + V+G+ + PSPT S P Sbjct: 179 EFPMSPVTSVHGGTYRCFSSHGFSHYLLSHPSDPLELIVSGSLEDPRPSPTRSVSTAAGP 238 Query: 144 -----------------RHLHVLIGTSVV-IILFILLLFFLLHRWCCNKKN--------- 176 RH VLIG VV I+L LLLF LL W K Sbjct: 239 EDQPLMPTGSVPHSGLRRHWEVLIGVLVVSILLLSLLLFLLLQHWRQGKHRTLAQRQADF 298 Query: 177 --------------------------------AVVMDQEPAGNRTVNREDSDEQDPQEVT 204 A V + +P ++ ++DPQ VT Sbjct: 299 QRPPGAAEPEPKDGGLQRRSSPAADVQGENFCAAVKNTQPEDGVEMDTRSPHDEDPQAVT 358 Query: 205 YAQLNHCVFTQRKITRPSQRPKTPPTDI 232 YA++ H +RP + +PP+ + Sbjct: 359 YAKVKH--------SRPRREMASPPSPL 378 Score = 53.9 bits (128), Expect = 1e-07 Identities = 43/140 (30%), Positives = 67/140 (47%), Gaps = 13/140 (9%) Query: 7 SMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKF 66 +++C+G L G KP+L A PG ++ +V + C + + + L +E Sbjct: 7 ALLCLGLSLGPRTHMQAGPLPKPTLWAEPGSVISWGNSVTIWCQGTLEAREYRLDKEESP 66 Query: 67 K--DTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTG 124 D + + + +KA FSI M +D AG YRCY SP S PSDPL + +TG Sbjct: 67 APWDRQNPL----EPKNKARFSIPSMTEDYAGRYRCY---YRSPVGWSQPSDPLELVMTG 119 Query: 125 NPS----NSWPSPTEPSSET 140 S ++ PSP S ++ Sbjct: 120 AYSKPTLSALPSPLVTSGKS 139 Score = 33.9 bits (76), Expect = 0.13 Identities = 17/58 (29%), Positives = 29/58 (50%) Query: 181 DQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTEL 238 D++ +R ++ E + + PQ+VTYAQL+ Q+ P + P + VY L Sbjct: 387 DRQAEEDRQMDTEAAASEAPQDVTYAQLHSFTLRQKATEPPPSQEGASPAEPSVYATL 444 >gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B, member 1 isoform 2 [Homo sapiens] Length = 652 Score = 102 bits (255), Expect = 2e-22 Identities = 82/248 (33%), Positives = 111/248 (44%), Gaps = 36/248 (14%) Query: 30 SLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGP 89 SL PGP V S E V L C S Q FLL +EG D L + +A F +GP Sbjct: 327 SLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGP 386 Query: 90 MMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSV---TGNPSNSWPSPTEPSS-------- 138 + AGTYRCYGS + PY L+ PSDPL + V +G PS+ PT S+ Sbjct: 387 VTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPSSPTTGPTSTSAGPEDQPLT 446 Query: 139 ------ETGNPRHLHVLIG--TSVVIILFILLLFFLLHR-------WCCNKKNAVVMDQE 183 ++G RHL V+IG +V+++L +LLL FL+ R W ++ A Q Sbjct: 447 PTGSDPQSGLGRHLGVVIGILVAVILLLLLLLLLFLILRHRRQGKHWTSTQRKADF--QH 504 Query: 184 PAG-------NRTVNREDSDEQDPQEVT-YAQLNHCVFTQRKITRPSQRPKTPPTDIIVY 235 PAG +R + S D QE YA + H Q P + Y Sbjct: 505 PAGAVGPEPTDRGLQWRSSPAADAQEENLYAAVKHTQPEDGVEMDTRQSPHDEDPQAVTY 564 Query: 236 TELPNAEP 243 E+ ++ P Sbjct: 565 AEVKHSRP 572 Score = 91.7 bits (226), Expect = 5e-19 Identities = 52/122 (42%), Positives = 74/122 (60%), Gaps = 8/122 (6%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIG-EHHDGVSK 82 GV +KPSL PGP+V EET+ LQC SD + F+L+++G+ +D L L G + G+S+ Sbjct: 221 GVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGE-RDFLQLAGAQPQAGLSQ 279 Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGN-----PSNSWPSPTEPS 137 ANF++GP+ + G YRCYG+ S + SAPSDPL + + G + P PT S Sbjct: 280 ANFTLGPVSRSYGGQYRCYGAHNLSS-EWSAPSDPLDILIAGQFYDRVSLSVQPGPTVAS 338 Query: 138 SE 139 E Sbjct: 339 GE 340 Score = 74.7 bits (182), Expect = 7e-14 Identities = 50/122 (40%), Positives = 66/122 (54%), Gaps = 5/122 (4%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHD-GVSK 82 G + KP+L A P P+V S VILQC S V F F L +EG+ + L + H G S+ Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179 Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSD---PLLVSVTGNPSNS-WPSPTEPSS 138 A FS+GP+ YRCY ++SPY+ S PSD L++ V+ PS S P P Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239 Query: 139 ET 140 ET Sbjct: 240 ET 241 Score = 52.0 bits (123), Expect = 5e-07 Identities = 41/125 (32%), Positives = 58/125 (46%), Gaps = 6/125 (4%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 M+ ++ ++C+G L G KP+L A PG ++ V L+C Q + L Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60 Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRC-YGSVTHSPYQLSAPSDPLL 119 +RE K L + + V K F I + + AG YRC YGS T S SDPL Sbjct: 61 YREK--KTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAG---RSESSDPLE 115 Query: 120 VSVTG 124 + VTG Sbjct: 116 LVVTG 120 Score = 31.6 bits (70), Expect = 0.65 Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 3/58 (5%) Query: 181 DQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITR--PSQRPKTPPTDIIVYT 236 D++ +R ++ E + + PQ+VTYAQL H + +R+ T PSQ +P I T Sbjct: 592 DRQAEEDRQMDTEAAASEAPQDVTYAQL-HSLTLRREATEPPPSQEGPSPAVPSIYAT 648 >gi|125987593 leukocyte immunoglobulin-like receptor, subfamily B, member 5 isoform 3 [Homo sapiens] Length = 491 Score = 102 bits (255), Expect = 2e-22 Identities = 76/265 (28%), Positives = 109/265 (41%), Gaps = 55/265 (20%) Query: 29 PSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKANFSIG 88 P+L PGP V S E V L C S + F L +EG L L ++ +A FS+ Sbjct: 224 PALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMS 283 Query: 89 PMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTG-------NPSNSWPSPTEPSS--- 138 P+ GTYRCY ++ PY LS+PS P + V+G +P+ S P+P P Sbjct: 284 PVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPL 343 Query: 139 -------ETGNPRHLHVLIGTSVVIILFILLLFFLLHRWCCNKK---------------- 175 ++G RHL V+ G SV +L + LL FLL R K Sbjct: 344 TPTGLDPQSGLGRHLGVVTGVSVAFVLLLFLLLFLLLRHRHQSKHRTSAHFYRPAGAAGP 403 Query: 176 ----------------------NAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVF 213 NA V D +P ++ + + PQ+VTYAQL+ Sbjct: 404 EPKDQGLQKRASPVADIQEEILNAAVKDTQPKDGVEMDARAAASEAPQDVTYAQLHSLTL 463 Query: 214 TQRKITRPSQRPKTPPTDIIVYTEL 238 + P + + PP + +Y L Sbjct: 464 RREATEPPPSQEREPPAEPSIYAPL 488 Score = 77.8 bits (190), Expect = 8e-15 Identities = 45/102 (44%), Positives = 65/102 (63%), Gaps = 3/102 (2%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEH-HDGVSK 82 GV RKPSLL G +V ++ LQC SDV + F+L++EG+ D + G+ G+S+ Sbjct: 119 GVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGE-HDLVQGSGQQPQAGLSQ 177 Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTG 124 ANF++GP+ + G YRCYG+ SP + SAPSDPL + + G Sbjct: 178 ANFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAG 218 Score = 50.4 bits (119), Expect = 1e-06 Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 15/129 (11%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 M+L + ++C+G + G KP+L A P ++ + V L C + + + L Sbjct: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60 Query: 61 HREG-----KFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPS 115 +EG K ++ L + +KA F I + D AG YRCY +P S PS Sbjct: 61 DKEGLPWARKRQNPL-------EPGAKAKFHIPSTVYDSAGRYRCY---YETPAGWSEPS 110 Query: 116 DPLLVSVTG 124 DPL + TG Sbjct: 111 DPLELVATG 119 >gi|125987591 leukocyte immunoglobulin-like receptor, subfamily B, member 5 isoform 1 [Homo sapiens] Length = 591 Score = 102 bits (255), Expect = 2e-22 Identities = 76/265 (28%), Positives = 109/265 (41%), Gaps = 55/265 (20%) Query: 29 PSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKANFSIG 88 P+L PGP V S E V L C S + F L +EG L L ++ +A FS+ Sbjct: 324 PALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMS 383 Query: 89 PMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTG-------NPSNSWPSPTEPSS--- 138 P+ GTYRCY ++ PY LS+PS P + V+G +P+ S P+P P Sbjct: 384 PVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPL 443 Query: 139 -------ETGNPRHLHVLIGTSVVIILFILLLFFLLHRWCCNKK---------------- 175 ++G RHL V+ G SV +L + LL FLL R K Sbjct: 444 TPTGLDPQSGLGRHLGVVTGVSVAFVLLLFLLLFLLLRHRHQSKHRTSAHFYRPAGAAGP 503 Query: 176 ----------------------NAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVF 213 NA V D +P ++ + + PQ+VTYAQL+ Sbjct: 504 EPKDQGLQKRASPVADIQEEILNAAVKDTQPKDGVEMDARAAASEAPQDVTYAQLHSLTL 563 Query: 214 TQRKITRPSQRPKTPPTDIIVYTEL 238 + P + + PP + +Y L Sbjct: 564 RREATEPPPSQEREPPAEPSIYAPL 588 Score = 77.8 bits (190), Expect = 8e-15 Identities = 45/102 (44%), Positives = 65/102 (63%), Gaps = 3/102 (2%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEH-HDGVSK 82 GV RKPSLL G +V ++ LQC SDV + F+L++EG+ D + G+ G+S+ Sbjct: 219 GVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGE-HDLVQGSGQQPQAGLSQ 277 Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTG 124 ANF++GP+ + G YRCYG+ SP + SAPSDPL + + G Sbjct: 278 ANFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAG 318 Score = 50.4 bits (119), Expect = 1e-06 Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 15/129 (11%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 M+L + ++C+G + G KP+L A P ++ + V L C + + + L Sbjct: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60 Query: 61 HREG-----KFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPS 115 +EG K ++ L + +KA F I + D AG YRCY +P S PS Sbjct: 61 DKEGLPWARKRQNPL-------EPGAKAKFHIPSTVYDSAGRYRCY---YETPAGWSEPS 110 Query: 116 DPLLVSVTG 124 DPL + TG Sbjct: 111 DPLELVATG 119 Score = 49.7 bits (117), Expect = 2e-06 Identities = 36/102 (35%), Positives = 50/102 (49%), Gaps = 2/102 (1%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWS-DVRFQHFLLHREGKFKDTLHLIGEHHDGVSK 82 G + +P+LLA P P+V S V LQC + D L+ E K TL+ + G S+ Sbjct: 119 GFYAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLYS-QKLPKGPSQ 177 Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTG 124 A F +GP+ +RCY +P S PSD L + V G Sbjct: 178 ALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPG 219 >gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B, member 1 isoform 3 [Homo sapiens] Length = 651 Score = 102 bits (254), Expect = 3e-22 Identities = 81/248 (32%), Positives = 114/248 (45%), Gaps = 37/248 (14%) Query: 30 SLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGP 89 SL PGP V S E V L C S Q FLL +EG D L + +A F +GP Sbjct: 327 SLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGP 386 Query: 90 MMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSV---TGNPSNSWPSPTEPSS-------- 138 + AGTYRCYGS + PY L+ PSDPL + V +G PS+ PT S+ Sbjct: 387 VTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPSSPTTGPTSTSAGPEDQPLT 446 Query: 139 ------ETGNPRHLHVLIG--TSVVIILFILLLFFLLHR-------WCCNKKNAVVMDQE 183 ++G RHL V+IG +V+++L +LLL FL+ R W ++ A Q Sbjct: 447 PTGSDPQSGLGRHLGVVIGILVAVILLLLLLLLLFLILRHRRQGKHWTSTQRKADF--QH 504 Query: 184 PAG-------NRTVNREDSDEQDPQEVT-YAQLNHCVFTQRKITRPSQRPKTPPTDIIVY 235 PAG +R + S D QE YA + H + + ++ P + Y Sbjct: 505 PAGAVGPEPTDRGLQWRSSPAADAQEENLYAAVKH-TQPEDGVEMDTRSPHDEDPQAVTY 563 Query: 236 TELPNAEP 243 E+ ++ P Sbjct: 564 AEVKHSRP 571 Score = 91.7 bits (226), Expect = 5e-19 Identities = 52/122 (42%), Positives = 74/122 (60%), Gaps = 8/122 (6%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIG-EHHDGVSK 82 GV +KPSL PGP+V EET+ LQC SD + F+L+++G+ +D L L G + G+S+ Sbjct: 221 GVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGE-RDFLQLAGAQPQAGLSQ 279 Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGN-----PSNSWPSPTEPS 137 ANF++GP+ + G YRCYG+ S + SAPSDPL + + G + P PT S Sbjct: 280 ANFTLGPVSRSYGGQYRCYGAHNLSS-EWSAPSDPLDILIAGQFYDRVSLSVQPGPTVAS 338 Query: 138 SE 139 E Sbjct: 339 GE 340 Score = 74.7 bits (182), Expect = 7e-14 Identities = 50/122 (40%), Positives = 66/122 (54%), Gaps = 5/122 (4%) Query: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHD-GVSK 82 G + KP+L A P P+V S VILQC S V F F L +EG+ + L + H G S+ Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179 Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSD---PLLVSVTGNPSNS-WPSPTEPSS 138 A FS+GP+ YRCY ++SPY+ S PSD L++ V+ PS S P P Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239 Query: 139 ET 140 ET Sbjct: 240 ET 241 Score = 52.0 bits (123), Expect = 5e-07 Identities = 41/125 (32%), Positives = 58/125 (46%), Gaps = 6/125 (4%) Query: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 M+ ++ ++C+G L G KP+L A PG ++ V L+C Q + L Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60 Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRC-YGSVTHSPYQLSAPSDPLL 119 +RE K L + + V K F I + + AG YRC YGS T S SDPL Sbjct: 61 YREK--KTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAG---RSESSDPLE 115 Query: 120 VSVTG 124 + VTG Sbjct: 116 LVVTG 120 Score = 31.6 bits (70), Expect = 0.65 Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 3/58 (5%) Query: 181 DQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITR--PSQRPKTPPTDIIVYT 236 D++ +R ++ E + + PQ+VTYAQL H + +R+ T PSQ +P I T Sbjct: 591 DRQAEEDRQMDTEAAASEAPQDVTYAQL-HSLTLRREATEPPPSQEGPSPAVPSIYAT 647 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.136 0.431 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,953,625 Number of Sequences: 37866 Number of extensions: 531391 Number of successful extensions: 2178 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 73 Number of HSP's successfully gapped in prelim test: 30 Number of HSP's that attempted gapping in prelim test: 1771 Number of HSP's gapped (non-prelim): 261 length of query: 243 length of database: 18,247,518 effective HSP length: 99 effective length of query: 144 effective length of database: 14,498,784 effective search space: 2087824896 effective search space used: 2087824896 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.