BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|66267727 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5B precursor [Homo sapiens] (375 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|66267727 killer cell immunoglobulin-like receptor, two domain... 773 0.0 gi|11968154 killer cell immunoglobulin-like receptor, two domain... 763 0.0 gi|124107606 killer cell immunoglobulin-like receptor, two domai... 601 e-172 gi|124107610 killer cell immunoglobulin-like receptor, two domai... 538 e-153 gi|71143139 killer cell immunoglobulin-like receptor, two domain... 445 e-125 gi|134304833 killer cell immunoglobulin-like receptor, two domai... 439 e-123 gi|110611923 killer cell immunoglobulin-like receptor, two domai... 436 e-122 gi|124107604 killer cell immunoglobulin-like receptor, two domai... 429 e-120 gi|134268644 killer cell immunoglobulin-like receptor, three dom... 419 e-117 gi|134268642 killer cell immunoglobulin-like receptor, three dom... 405 e-113 gi|116517309 killer cell immunoglobulin-like receptor, two domai... 379 e-105 gi|6912472 killer cell immunoglobulin-like receptor, two domains... 378 e-105 gi|134304835 killer cell immunoglobulin-like receptor, two domai... 375 e-104 gi|6912474 killer cell immunoglobulin-like receptor, two domains... 370 e-103 gi|7657277 killer cell immunoglobulin-like receptor, two domains... 363 e-100 gi|46488946 killer cell immunoglobulin-like receptor, three doma... 353 2e-97 gi|134133244 killer cell immunoglobulin-like receptor, three dom... 290 1e-78 gi|62632748 killer-cell Ig-like receptor [Homo sapiens] 271 5e-73 gi|71143143 killer cell immunoglobulin-like receptor, two domain... 266 2e-71 gi|239747104 PREDICTED: hypothetical protein XP_002344494 [Homo ... 199 4e-51 gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B... 183 2e-46 gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B... 181 7e-46 gi|5803070 leukocyte immunoglobulin-like receptor, subfamily B, ... 177 1e-44 gi|125987593 leukocyte immunoglobulin-like receptor, subfamily B... 177 1e-44 gi|125987591 leukocyte immunoglobulin-like receptor, subfamily B... 177 1e-44 gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B... 171 1e-42 gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B... 171 1e-42 gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B... 164 2e-40 gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B... 163 2e-40 gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B... 163 3e-40 >gi|66267727 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5B precursor [Homo sapiens] Length = 375 Score = 773 bits (1995), Expect = 0.0 Identities = 375/375 (100%), Positives = 375/375 (100%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL Sbjct: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 Query: 61 YKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGL 120 YKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGL Sbjct: 61 YKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGL 120 Query: 121 FGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADF 180 FGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADF Sbjct: 121 FGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADF 180 Query: 181 PLGPATHGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLH 240 PLGPATHGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLH Sbjct: 181 PLGPATHGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLH 240 Query: 241 ILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQGPAGDRTVNREDSDDQDPQEVTYAQ 300 ILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQGPAGDRTVNREDSDDQDPQEVTYAQ Sbjct: 241 ILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQGPAGDRTVNREDSDDQDPQEVTYAQ 300 Query: 301 LDHCVFTQTKITSPSQRPKAPPTDTTMYMELPNAKPRSLSPAHKHHSQALRGSSRETTAL 360 LDHCVFTQTKITSPSQRPKAPPTDTTMYMELPNAKPRSLSPAHKHHSQALRGSSRETTAL Sbjct: 301 LDHCVFTQTKITSPSQRPKAPPTDTTMYMELPNAKPRSLSPAHKHHSQALRGSSRETTAL 360 Query: 361 SQNRVASSHVPAAGI 375 SQNRVASSHVPAAGI Sbjct: 361 SQNRVASSHVPAAGI 375 >gi|11968154 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A [Homo sapiens] Length = 375 Score = 763 bits (1970), Expect = 0.0 Identities = 370/375 (98%), Positives = 371/375 (98%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL Sbjct: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 Query: 61 YKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGL 120 YKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGL Sbjct: 61 YKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGL 120 Query: 121 FGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADF 180 FGKPSLSAQPGPTVRTGENV LSCSSRSSFDMYHLSREGRAHEPRLPAVPSV+GTFQADF Sbjct: 121 FGKPSLSAQPGPTVRTGENVTLSCSSRSSFDMYHLSREGRAHEPRLPAVPSVNGTFQADF 180 Query: 181 PLGPATHGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLH 240 PLGPATHGGTYTCF SLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLH Sbjct: 181 PLGPATHGGTYTCFGSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLH 240 Query: 241 ILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQGPAGDRTVNREDSDDQDPQEVTYAQ 300 ILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQ PAGDRTVNREDSDDQDPQEVTYAQ Sbjct: 241 ILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQEPAGDRTVNREDSDDQDPQEVTYAQ 300 Query: 301 LDHCVFTQTKITSPSQRPKAPPTDTTMYMELPNAKPRSLSPAHKHHSQALRGSSRETTAL 360 LDHCVFTQTKITSPSQRPK PPTDTTMYMELPNAKPRSLSPAHKHHSQALRGSSRETTAL Sbjct: 301 LDHCVFTQTKITSPSQRPKTPPTDTTMYMELPNAKPRSLSPAHKHHSQALRGSSRETTAL 360 Query: 361 SQNRVASSHVPAAGI 375 SQNRVASSHVPAAGI Sbjct: 361 SQNRVASSHVPAAGI 375 >gi|124107606 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 isoform a [Homo sapiens] Length = 377 Score = 601 bits (1549), Expect = e-172 Identities = 292/375 (77%), Positives = 320/375 (85%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 MS VI +AC+GFFL Q W H GGQDKP SAWPSAVVP+GGHVTL C R GF IF+L Sbjct: 3 MSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTL 62 Query: 61 YKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGL 120 YK+DGVPVPELYN+IFW S L+ PVTPAHAGTYRCRG HP SP EWSAPSNPLVI+VTGL Sbjct: 63 YKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGL 122 Query: 121 FGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADF 180 + KPSL+A+PGPTVR GENV LSCSS+SSFD+YHLSREG AHE RLPAVPS++GTFQADF Sbjct: 123 YEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADF 182 Query: 181 PLGPATHGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLH 240 PLGPATHG TY CF S H SPYEWSDPSDPL VSVTGN SSS SPTEPS KTGI RHLH Sbjct: 183 PLGPATHGETYRCFGSFHGSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKTGIARHLH 242 Query: 241 ILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQGPAGDRTVNREDSDDQDPQEVTYAQ 300 +I SVAIILF IL FFLLH CS KKNAAVM+Q PAG RTVNREDSD+QDPQEVTYAQ Sbjct: 243 AVIRYSVAIILFTILPFFLLHRWCSKKKNAAVMNQEPAGHRTVNREDSDEQDPQEVTYAQ 302 Query: 301 LDHCVFTQTKITSPSQRPKAPPTDTTMYMELPNAKPRSLSPAHKHHSQALRGSSRETTAL 360 LDHC+FTQ KIT PSQR K P TDT++ +ELPNA+PR+LSPAH+HHSQAL GSSRETTAL Sbjct: 303 LDHCIFTQRKITGPSQRSKRPSTDTSVCIELPNAEPRALSPAHEHHSQALMGSSRETTAL 362 Query: 361 SQNRVASSHVPAAGI 375 SQ ++ASS+VPAAGI Sbjct: 363 SQTQLASSNVPAAGI 377 >gi|124107610 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 isoform c [Homo sapiens] Length = 342 Score = 538 bits (1385), Expect = e-153 Identities = 266/375 (70%), Positives = 294/375 (78%), Gaps = 35/375 (9%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 MS VI +AC+GFFL Q W H GGQDKP SAWPSAVVP+GGHVTL C R GF IF+L Sbjct: 3 MSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTL 62 Query: 61 YKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGL 120 YK+DGVPVPELYN+IFW S L+ PVTPAHAGTYRCRG HP SP EWSAPSNPLVI+VTGL Sbjct: 63 YKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGL 122 Query: 121 FGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADF 180 + KPSL+A+PGPTVR GENV LSCSS+SSFD+YHLSREG AHE RLPAVPS++GTFQADF Sbjct: 123 YEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADF 182 Query: 181 PLGPATHGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLH 240 PLGPATHG TY CF S H SPYEWSDPSDPL VSVTGN SSS SPTEPS KT Sbjct: 183 PLGPATHGETYRCFGSFHGSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKT------- 235 Query: 241 ILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQGPAGDRTVNREDSDDQDPQEVTYAQ 300 +AAVM+Q PAG RTVNREDSD+QDPQEVTYAQ Sbjct: 236 ----------------------------DAAVMNQEPAGHRTVNREDSDEQDPQEVTYAQ 267 Query: 301 LDHCVFTQTKITSPSQRPKAPPTDTTMYMELPNAKPRSLSPAHKHHSQALRGSSRETTAL 360 LDHC+FTQ KIT PSQR K P TDT++ +ELPNA+PR+LSPAH+HHSQAL GSSRETTAL Sbjct: 268 LDHCIFTQRKITGPSQRSKRPSTDTSVCIELPNAEPRALSPAHEHHSQALMGSSRETTAL 327 Query: 361 SQNRVASSHVPAAGI 375 SQ ++ASS+VPAAGI Sbjct: 328 SQTQLASSNVPAAGI 342 >gi|71143139 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 isoform 2 [Homo sapiens] Length = 341 Score = 445 bits (1145), Expect = e-125 Identities = 228/341 (66%), Positives = 257/341 (75%), Gaps = 5/341 (1%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 MSLMV+SM CVGFFLLQGAW HEG KP L A P +V V L C S + F F L Sbjct: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 Query: 61 YKEDGVP-----VPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVI 115 ++E + E ++ + + +GP+ AGTYRC GS SP + SAPS+PL I Sbjct: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120 Query: 116 VVTGLFGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGT 175 V+TGL+ KPSLSAQPGPTV GE+V LSCSSRSS+DMYHLSREG AHE R A P V+GT Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGT 180 Query: 176 FQADFPLGPATHGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGI 235 FQADFPLGPATHGGTY CF S DSPYEWS+ SDPLLVSVTGN S+S SPTEPSS+TG Sbjct: 181 FQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSETGN 240 Query: 236 RRHLHILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQGPAGDRTVNREDSDDQDPQE 295 RHLH+LIGTSV IILFI+L FFLLH C NKKNA VMDQ PAG+RTVNREDSD+QDPQE Sbjct: 241 PRHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQE 300 Query: 296 VTYAQLDHCVFTQTKITSPSQRPKAPPTDTTMYMELPNAKP 336 VTYAQL+HCVFTQ KIT PSQRPK PPTD +Y ELPNA+P Sbjct: 301 VTYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAEP 341 >gi|134304833 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 precursor [Homo sapiens] Length = 348 Score = 439 bits (1129), Expect = e-123 Identities = 230/343 (67%), Positives = 257/343 (74%), Gaps = 6/343 (1%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 MSLMV+SMACVGFFLLQGAW HEG KP L A P +V V L C S + F F L Sbjct: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60 Query: 61 YKEDGVP-----VPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVI 115 ++E + E ++ + + +GP+ AGTYRC GS SP + SAPS+PL I Sbjct: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120 Query: 116 VVTGLFGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGT 175 V+TGL+ KPSLSAQPGPTV GE+V LSCSSRSS+DMYHLSREG AHE R A P V+GT Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT 180 Query: 176 FQADFPLGPATHGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGI 235 FQADFPLGPATHGGTY CF S DSPYEWS+ SDPLLVSVTGN S+S SPTEPSSKTG Sbjct: 181 FQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240 Query: 236 RRHLHILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQGPAGDRTVNREDSDDQDPQE 295 RHLHILIGTSV IILFI+L FFLLH CSNKKNAAVMDQ AG+RT N EDSD+QDPQE Sbjct: 241 PRHLHILIGTSVVIILFILL-FFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQE 299 Query: 296 VTYAQLDHCVFTQTKITSPSQRPKAPPTDTTMYMELPNAKPRS 338 VTY QL+HCVFTQ KIT PSQRPK PPTD +Y ELPNA+ RS Sbjct: 300 VTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRS 342 >gi|110611923 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 [Homo sapiens] Length = 348 Score = 436 bits (1121), Expect = e-122 Identities = 230/343 (67%), Positives = 256/343 (74%), Gaps = 6/343 (1%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 MSL+V+SMACVGFFLLQGAW HEG KP L A P +V V L C S + F F L Sbjct: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60 Query: 61 YKEDGVP-----VPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVI 115 ++E + E ++ + + + +T AGTYRC GS SP + SAPS+PL I Sbjct: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120 Query: 116 VVTGLFGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGT 175 V+ GL+ KPSLSAQ GPTV GENV LSCSSRSS+DMYHLSREG AHE RLPA P V+GT Sbjct: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGT 180 Query: 176 FQADFPLGPATHGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGI 235 FQADFPLGPATHGGTY CF S HDSPYEWS SDPLLVSVTGN S+S SPTEPSSKTG Sbjct: 181 FQADFPLGPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240 Query: 236 RRHLHILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQGPAGDRTVNREDSDDQDPQE 295 RHLHILIGTSV IILFI+L FFLLH CSNKKNAAVMDQ AG+RT N EDSD+QDPQE Sbjct: 241 PRHLHILIGTSVVIILFILL-FFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQE 299 Query: 296 VTYAQLDHCVFTQTKITSPSQRPKAPPTDTTMYMELPNAKPRS 338 VTY QL+HCVFTQ KIT PSQRPK PPTD +Y ELPNA+ RS Sbjct: 300 VTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRS 342 >gi|124107604 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 isoform b [Homo sapiens] Length = 273 Score = 429 bits (1104), Expect = e-120 Identities = 207/268 (77%), Positives = 223/268 (83%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 MS VI +AC+GFFL Q W H GGQDKP SAWPSAVVP+GGHVTL C R GF IF+L Sbjct: 3 MSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTL 62 Query: 61 YKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGL 120 YK+DGVPVPELYN+IFW S L+ PVTPAHAGTYRCRG HP SP EWSAPSNPLVI+VTGL Sbjct: 63 YKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGL 122 Query: 121 FGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADF 180 + KPSL+A+PGPTVR GENV LSCSS+SSFD+YHLSREG AHE RLPAVPS++GTFQADF Sbjct: 123 YEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADF 182 Query: 181 PLGPATHGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLH 240 PLGPATHG TY CF S H SPYEWSDPSDPL VSVTGN SSS SPTEPS KTGI RHLH Sbjct: 183 PLGPATHGETYRCFGSFHGSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKTGIARHLH 242 Query: 241 ILIGTSVAIILFIILFFFLLHCCCSNKK 268 +I SVAIILF IL FFLLH CS KK Sbjct: 243 AVIRYSVAIILFTILPFFLLHRWCSKKK 270 >gi|134268644 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 precursor [Homo sapiens] Length = 444 Score = 419 bits (1078), Expect = e-117 Identities = 218/321 (67%), Positives = 244/321 (76%), Gaps = 7/321 (2%) Query: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVP------VPELYNKIFW 77 G KP L A P +V G V L C S + F F L+KE G+ V ++++ + Sbjct: 119 GNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKE-GISKDPSRLVGQIHDGVSK 177 Query: 78 KSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLFGKPSLSAQPGPTVRTG 137 + +GP+ A AGTYRC GS +P + SAPS+PL IVVTG + KPSLSAQPGP V+ G Sbjct: 178 ANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAG 237 Query: 138 ENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADFPLGPATHGGTYTCFSSL 197 E+V LSCSSRSS+DMYHLSREG AHE RLPAV V+ TFQADFPLGPATHGGTY CF S Sbjct: 238 ESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSF 297 Query: 198 HDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLHILIGTSVAIILFIILFF 257 SPYEWSDPSDPLLVSVTGN SSS SPTEPSSK+G RHLHILIGTSV IILFI+L F Sbjct: 298 RHSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNPRHLHILIGTSVVIILFILLLF 357 Query: 258 FLLHCCCSNKKNAAVMDQGPAGDRTVNREDSDDQDPQEVTYAQLDHCVFTQTKITSPSQR 317 FLLH CSNKKNAAVMDQ PAG+RT N EDSD+QDP+EVTYAQLDHCVFTQ KIT PSQR Sbjct: 358 FLLHLWCSNKKNAAVMDQEPAGNRTANSEDSDEQDPEEVTYAQLDHCVFTQRKITRPSQR 417 Query: 318 PKAPPTDTTMYMELPNAKPRS 338 PK PPTDT +Y ELPNAKPRS Sbjct: 418 PKTPPTDTILYTELPNAKPRS 438 Score = 241 bits (616), Expect = 6e-64 Identities = 127/234 (54%), Positives = 152/234 (64%), Gaps = 3/234 (1%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 MSLMV+SMACVG FL+Q A H GGQDKP LSAWPSAVVPRGGHVTL C R F F L Sbjct: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 Query: 61 YKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGL 120 YKED + +P + +IF +S M PVT AHAG Y CRGSHP SP WSAPSNP+VI+VTG Sbjct: 61 YKEDRIHIPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGN 120 Query: 121 FGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADF 180 KPSL A PGP V++GE V L C S F+ + L +EG + +P DG +A+F Sbjct: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANF 180 Query: 181 PLGP--ATHGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSK 232 +GP GTY C+ S+ +PY+ S PSDPL + VTG S S +P K Sbjct: 181 SIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLS-AQPGPK 233 >gi|134268642 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 precursor [Homo sapiens] Length = 455 Score = 405 bits (1042), Expect = e-113 Identities = 210/321 (65%), Positives = 243/321 (75%), Gaps = 7/321 (2%) Query: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVP------VPELYNKIFW 77 G KP L A P ++ G V L C S + F F L++E G+ V ++++ + Sbjct: 119 GNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHRE-GISEDPSRLVGQIHDGVSK 177 Query: 78 KSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLFGKPSLSAQPGPTVRTG 137 + +GP+ P AGTYRC GS P SP + SAPS+PL IV+TGL+ KPSLSAQPGPTV+ G Sbjct: 178 ANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAG 237 Query: 138 ENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADFPLGPATHGGTYTCFSSL 197 ENV LSCSS SS+D+YHLSREG AHE RL AVP V+ TFQADFPLGPATHGGTY CF S Sbjct: 238 ENVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPATHGGTYRCFGSF 297 Query: 198 HDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLHILIGTSVAIILFIILFF 257 P WS+ SDPLLVSVTGN SSS SPTEPSSK+GI RHLH+LIGTSV I LFI+L F Sbjct: 298 RALPCVWSNSSDPLLVSVTGNPSSSWPSPTEPSSKSGICRHLHVLIGTSVVIFLFILLLF 357 Query: 258 FLLHCCCSNKKNAAVMDQGPAGDRTVNREDSDDQDPQEVTYAQLDHCVFTQTKITSPSQR 317 FLL+ CSNKKNAAVMDQ PAGDRTVNR+DSD+QDPQEVTYAQLDHCVF Q KI+ PSQR Sbjct: 358 FLLYRWCSNKKNAAVMDQEPAGDRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISRPSQR 417 Query: 318 PKAPPTDTTMYMELPNAKPRS 338 PK P TDT++Y ELPNA+PRS Sbjct: 418 PKTPLTDTSVYTELPNAEPRS 438 Score = 246 bits (628), Expect = 2e-65 Identities = 131/233 (56%), Positives = 153/233 (65%), Gaps = 6/233 (2%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 MSL V+SMACVGFFLLQGAW GGQDKP LSA PS VVPRGGHV L C R GF F L Sbjct: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 Query: 61 YKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGL 120 YKED VP + +IF +S +MGPVTPAHAGTYRCRGS P S WSAPSNPLVI+VTG Sbjct: 61 YKEDRSHVPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGN 120 Query: 121 FGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADF 180 KPSL A PGP +++GE V L C S F+ + L REG + +P DG +A+F Sbjct: 121 HRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANF 180 Query: 181 PLGP--ATHGGTYTCFSSLHDSPYEWSDPSDPLLVSVTG----NSSSSSSSPT 227 +GP GTY C+ S+ SPY+ S PSDPL + +TG S S+ PT Sbjct: 181 SIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPT 233 >gi|116517309 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4 [Homo sapiens] Length = 304 Score = 379 bits (972), Expect = e-105 Identities = 198/304 (65%), Positives = 226/304 (74%), Gaps = 5/304 (1%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 MSLMVI MACVGFFLLQGAW EG KP A P +V V L C S + F F L Sbjct: 1 MSLMVIIMACVGFFLLQGAWPQEGVHRKPSFLALPGHLVKSEETVILQCWSDVMFEHFLL 60 Query: 61 YKEDGVP-----VPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVI 115 ++E + E ++ + + +GP+ P AGTYRC GS P SP + SAPS+PL + Sbjct: 61 HREGKFNNTLHLIGEHHDGVSKANFSIGPMMPVLAGTYRCYGSVPHSPYQLSAPSDPLDM 120 Query: 116 VVTGLFGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGT 175 V+ GL+ KPSLSAQPGPTV+ GENV LSCSSRSS+DMYHLSREG AHE RLPAV S++GT Sbjct: 121 VIIGLYEKPSLSAQPGPTVQAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAVRSINGT 180 Query: 176 FQADFPLGPATHGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGI 235 FQADFPLGPATHGGTY CF S D+PYEWS+ SDPLLVSVTGN S+S SPTEPSSKTG Sbjct: 181 FQADFPLGPATHGGTYRCFGSFRDAPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240 Query: 236 RRHLHILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQGPAGDRTVNREDSDDQDPQE 295 RHLH+LIGTSV I F IL FFLLH CS+KKNAAVMDQ PAG+RTVN EDSD+QD QE Sbjct: 241 PRHLHVLIGTSVVKIPFTILLFFLLHRWCSDKKNAAVMDQEPAGNRTVNSEDSDEQDHQE 300 Query: 296 VTYA 299 V+YA Sbjct: 301 VSYA 304 >gi|6912472 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2 precursor [Homo sapiens] Length = 304 Score = 378 bits (970), Expect = e-105 Identities = 199/304 (65%), Positives = 224/304 (73%), Gaps = 5/304 (1%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 MSLMV+SMACVGFFLLQGAW HEG KP L A P +V V L C S + F F L Sbjct: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFEHFLL 60 Query: 61 YKEDGVP-----VPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVI 115 ++E + E ++ + + +GP+ AGTYRC GS SP + SAPS+PL I Sbjct: 61 HREGKYKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120 Query: 116 VVTGLFGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGT 175 V+TGL+ KPSLSAQPGPTV GE+V LSCSSRSS+DMYHLSREG AHE R A P V+GT Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGT 180 Query: 176 FQADFPLGPATHGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGI 235 FQADFPLGPATHGGTY CF S DSPYEWS+ SDPLLVSVTGN S+S SPTEPSSKTG Sbjct: 181 FQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240 Query: 236 RRHLHILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQGPAGDRTVNREDSDDQDPQE 295 RHLH+LIGTSV I F IL FFLLH CSNKKNAAVMDQ PAG+RTVN EDSD+QD QE Sbjct: 241 PRHLHVLIGTSVVKIPFTILLFFLLHRWCSNKKNAAVMDQEPAGNRTVNSEDSDEQDHQE 300 Query: 296 VTYA 299 V+YA Sbjct: 301 VSYA 304 >gi|134304835 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5 [Homo sapiens] Length = 304 Score = 375 bits (962), Expect = e-104 Identities = 199/304 (65%), Positives = 225/304 (74%), Gaps = 5/304 (1%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 MSLMVISMACV FFLLQGAW HEG + KP L A P +V V L C S + F F L Sbjct: 1 MSLMVISMACVAFFLLQGAWPHEGFRRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLL 60 Query: 61 YKEDGVP-----VPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVI 115 ++E + E + + + +G +T AGTYRC GS SP + SAPS+PL I Sbjct: 61 HREGTFNHTLRLIGEHIDGVSKGNFSIGRMTQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120 Query: 116 VVTGLFGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGT 175 V+TGL+ KPSLSAQPGPTV GE+V LSCSSRSS+DMYHLSREG AHE RLPA P V+ T Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNRT 180 Query: 176 FQADFPLGPATHGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGI 235 FQADFPL PATHGGTY CF S DSPYEWS SDPLLVSVTGNSS+S SPTEPSS+TG Sbjct: 181 FQADFPLDPATHGGTYRCFGSFRDSPYEWSKSSDPLLVSVTGNSSNSWPSPTEPSSETGN 240 Query: 236 RRHLHILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQGPAGDRTVNREDSDDQDPQE 295 RHLH+LIGTSV + F IL FFLLH CSNKKNA+VMDQGPAG+RTVNREDSD+QD QE Sbjct: 241 PRHLHVLIGTSVVKLPFTILLFFLLHRWCSNKKNASVMDQGPAGNRTVNREDSDEQDHQE 300 Query: 296 VTYA 299 V+YA Sbjct: 301 VSYA 304 >gi|6912474 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3 [Homo sapiens] Length = 304 Score = 370 bits (951), Expect = e-103 Identities = 196/304 (64%), Positives = 223/304 (73%), Gaps = 5/304 (1%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 MSLMVISMACVGFF LQGAW HEG + KP L A P +V V L C S + F F L Sbjct: 1 MSLMVISMACVGFFWLQGAWPHEGFRRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60 Query: 61 YKEDGVP-----VPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVI 115 ++E + E + + + +G + AGTYRC GS P SP ++SAPS+PL I Sbjct: 61 HREGTFNDTLRLIGEHIDGVSKANFSIGRMRQDLAGTYRCYGSVPHSPYQFSAPSDPLDI 120 Query: 116 VVTGLFGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGT 175 V+TGL+ KPSLSAQPGPTV GE+V LSCSS SS+DMYHLS EG AHE R A P V+GT Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSWSSYDMYHLSTEGEAHERRFSAGPKVNGT 180 Query: 176 FQADFPLGPATHGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGI 235 FQADFPLGPAT GGTY CF S HDSPYEWS SDPLLVSVTGN S+S SPTEPSSKTG Sbjct: 181 FQADFPLGPATQGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240 Query: 236 RRHLHILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQGPAGDRTVNREDSDDQDPQE 295 RHLH+LIGTSV + F IL FFLLH CS+KKNA+VMDQGPAG+RTVNREDSD+QD QE Sbjct: 241 PRHLHVLIGTSVVKLPFTILLFFLLHRWCSDKKNASVMDQGPAGNRTVNREDSDEQDHQE 300 Query: 296 VTYA 299 V+YA Sbjct: 301 VSYA 304 >gi|7657277 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 precursor [Homo sapiens] Length = 304 Score = 363 bits (933), Expect = e-100 Identities = 194/304 (63%), Positives = 220/304 (72%), Gaps = 5/304 (1%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 MSL V+SMACVGFFLLQGAW HEG KP L A P +V V L C S + F F L Sbjct: 1 MSLTVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60 Query: 61 YKEDGVP-----VPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVI 115 ++E + E ++ + + + + AGTYRC GS SP + SAPS+PL I Sbjct: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMKQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120 Query: 116 VVTGLFGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGT 175 V+ GL+ KPSLSAQPGPTV GENV LSCSSRSS+DMYHLSREG AHE RLPA V+GT Sbjct: 121 VIIGLYEKPSLSAQPGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGTKVNGT 180 Query: 176 FQADFPLGPATHGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGI 235 FQA+FPLGPATHGGTY CF S DSPYEWS SDPLLVSVTGN S+S SPTEPSS+TG Sbjct: 181 FQANFPLGPATHGGTYRCFGSFRDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSETGN 240 Query: 236 RRHLHILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQGPAGDRTVNREDSDDQDPQE 295 RHLH+LIGTSV I F IL FFLLH CS+KKNAAVMDQ PAG+RTVN EDSD+QD QE Sbjct: 241 PRHLHVLIGTSVVKIPFTILLFFLLHRWCSDKKNAAVMDQEPAGNRTVNSEDSDEQDHQE 300 Query: 296 VTYA 299 V+YA Sbjct: 301 VSYA 304 >gi|46488946 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 [Homo sapiens] Length = 410 Score = 353 bits (905), Expect = 2e-97 Identities = 191/309 (61%), Positives = 214/309 (69%), Gaps = 22/309 (7%) Query: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVPVP-----ELYNKIFWK 78 G KP L A P +V G V L C S + F F L++E P +L++ Sbjct: 119 GVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQV 178 Query: 79 SILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLFGKPSLSAQPGPTVRTGE 138 + MGP+TPA AGTYRC GS P E SAPS+PL IVV GL+GKPSLSAQPGPTV+ GE Sbjct: 179 NYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGE 238 Query: 139 NVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADFPLGPATHGGTYTCFSSLH 198 NV LSCSSRS FD+YHLSRE A E RL AV V+GTFQA+FPLGP THGG Y CF S Sbjct: 239 NVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFR 298 Query: 199 DSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLHILIGTSVAIILFIILFFF 258 P+ WSDPSDPL VSVTGNS RHLH+LIGTSV II F IL FF Sbjct: 299 ALPHAWSDPSDPLPVSVTGNS-----------------RHLHVLIGTSVVIIPFAILLFF 341 Query: 259 LLHCCCSNKKNAAVMDQGPAGDRTVNREDSDDQDPQEVTYAQLDHCVFTQTKITSPSQRP 318 LLH C+NKKNA VMDQ PAG+RTVNREDSD+QDPQEVTYAQL+HCVFTQ KIT PSQRP Sbjct: 342 LLHRWCANKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRP 401 Query: 319 KAPPTDTTM 327 K PPTDT++ Sbjct: 402 KTPPTDTSV 410 Score = 267 bits (683), Expect = 1e-71 Identities = 139/233 (59%), Positives = 157/233 (67%), Gaps = 6/233 (2%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 MSLMV+SMACVGFFLL+G W H GGQDKP LSAWP VV G HVTL CRSRLGF FSL Sbjct: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60 Query: 61 YKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGL 120 KEDG+PVPELYN+IF S LMGPVTPAHAGTYRC SHP SP WSAPSNP+VI+VTG+ Sbjct: 61 SKEDGMPVPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGV 120 Query: 121 FGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADF 180 KPSL A PGP V++GE V L C S F+ + L REG +P D Q ++ Sbjct: 121 HRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNY 180 Query: 181 PLGPATH--GGTYTCFSSLHDSPYEWSDPSDPLLVSVTG----NSSSSSSSPT 227 +GP T GTY CF S+ PYE S PSDPL + V G S S+ PT Sbjct: 181 SMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPT 233 >gi|134133244 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1 [Homo sapiens] Length = 382 Score = 290 bits (743), Expect = 1e-78 Identities = 157/250 (62%), Positives = 177/250 (70%), Gaps = 5/250 (2%) Query: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKE-----DGVPVPELYNKIFWK 78 G KP L A P +V G V L C S + F F L+KE V ++++ + Sbjct: 119 GNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKA 178 Query: 79 SILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLFGKPSLSAQPGPTVRTGE 138 + +G + A AGTYRC GS +P + SAPS+PL IVVTGL+ KPSLSAQPGP V+ GE Sbjct: 179 NFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGE 238 Query: 139 NVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADFPLGPATHGGTYTCFSSLH 198 +V LSCSSRSS+DMYHLSREG AHE RLPAV V+ TFQADFPLGPATHGGTY CF S Sbjct: 239 SVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFR 298 Query: 199 DSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLHILIGTSVAIILFIILFFF 258 SPYEWSDPSDPLLVSVTGN SSS SPTEPSSK+G RHLHILIGTSV I F IL FF Sbjct: 299 HSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFF 358 Query: 259 LLHCCCSNKK 268 LLH CSNKK Sbjct: 359 LLHRWCSNKK 368 Score = 233 bits (593), Expect = 3e-61 Identities = 124/234 (52%), Positives = 148/234 (63%), Gaps = 3/234 (1%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 M LMV+SMACVG FL+Q A H GGQDKP LSAWPSAVVPRGGHVTL C R F F L Sbjct: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 Query: 61 YKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGL 120 YKED + VP + +IF + M PVT AHAG Y CRGSHP SP WSAPSNP+VI+VTG Sbjct: 61 YKEDRIHVPIFHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGN 120 Query: 121 FGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADF 180 KPSL A PGP V++GE V L C S F+ + L +E + +P DG +A+F Sbjct: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANF 180 Query: 181 PLGPATH--GGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSK 232 +G GTY C+ S+ +PY+ S PSDPL + VTG S S +P K Sbjct: 181 SIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLS-AQPGPK 233 >gi|62632748 killer-cell Ig-like receptor [Homo sapiens] Length = 328 Score = 271 bits (694), Expect = 5e-73 Identities = 140/237 (59%), Positives = 164/237 (69%), Gaps = 3/237 (1%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 MSLMVISMACVGFFLLQGAWTHEGGQDKP LSAWPS VV G HV L CRSRLGF FSL Sbjct: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPFLSAWPSPVVSEGEHVALQCRSRLGFNEFSL 60 Query: 61 YKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGL 120 KEDG+PVPELYN++F ++ +GPVTPAHAGTYRCRGSHP WSAPSNPLVI+VTG+ Sbjct: 61 SKEDGMPVPELYNRVFRNTVFIGPVTPAHAGTYRCRGSHPHFLTGWSAPSNPLVIMVTGV 120 Query: 121 FGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADF 180 KPSL A PGP V++ E V L C S F+ + L REG+ ++ DG +A+F Sbjct: 121 HRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLLHREGKFNDTLRLTGELHDGVSKANF 180 Query: 181 PLGPATH--GGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSS-SSPTEPSSKTG 234 +G T GTY C+ S+ SPY+ S PSDPL + +TG S S+ P K G Sbjct: 181 SIGRMTQDLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLCGKPSLSAQPRPMVKAG 237 Score = 218 bits (555), Expect = 7e-57 Identities = 117/198 (59%), Positives = 136/198 (68%), Gaps = 5/198 (2%) Query: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVP-----VPELYNKIFWK 78 G KP L A P +V V L C S + F F L++E EL++ + Sbjct: 119 GVHRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLLHREGKFNDTLRLTGELHDGVSKA 178 Query: 79 SILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLFGKPSLSAQPGPTVRTGE 138 + +G +T AGTYRC GS P SP + SAPS+PL IV+TGL GKPSLSAQP P V+ GE Sbjct: 179 NFSIGRMTQDLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLCGKPSLSAQPRPMVKAGE 238 Query: 139 NVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADFPLGPATHGGTYTCFSSLH 198 +V LSCSSRSS+D+YHLSREG AHE R PAVP V+GTFQA+FPLGPATHGGTY CF S Sbjct: 239 SVTLSCSSRSSYDIYHLSREGEAHELRFPAVPKVNGTFQANFPLGPATHGGTYRCFGSFR 298 Query: 199 DSPYEWSDPSDPLLVSVT 216 DSPYEWSD SDPLLVSVT Sbjct: 299 DSPYEWSDLSDPLLVSVT 316 >gi|71143143 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 isoform 1 [Homo sapiens] Length = 243 Score = 266 bits (681), Expect = 2e-71 Identities = 138/220 (62%), Positives = 159/220 (72%), Gaps = 2/220 (0%) Query: 119 GLFGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQA 178 G+ KPSL A PGP V++ E V L C S F + L REG+ + DG +A Sbjct: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 Query: 179 DFPLGPATH--GGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIR 236 +F +GP GTY C+ S+ SPY+ S PSDPLLVSVTGN S+S SPTEPSS+TG Sbjct: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNP 143 Query: 237 RHLHILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQGPAGDRTVNREDSDDQDPQEV 296 RHLH+LIGTSV IILFI+L FFLLH C NKKNA VMDQ PAG+RTVNREDSD+QDPQEV Sbjct: 144 RHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEV 203 Query: 297 TYAQLDHCVFTQTKITSPSQRPKAPPTDTTMYMELPNAKP 336 TYAQL+HCVFTQ KIT PSQRPK PPTD +Y ELPNA+P Sbjct: 204 TYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAEP 243 Score = 101 bits (251), Expect = 1e-21 Identities = 63/143 (44%), Positives = 82/143 (57%), Gaps = 9/143 (6%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 MSLMV+SM CVGFFLLQGAW HEG KP L A P +V V L C S + F F L Sbjct: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 Query: 61 YKEDGVP-----VPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVI 115 ++E + E ++ + + +GP+ AGTYRC GS SP + SAPS+PL++ Sbjct: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120 Query: 116 VVTGLFGKPSLSAQPGPTVRTGE 138 VT G PS ++ P PT + E Sbjct: 121 SVT---GNPS-NSWPSPTEPSSE 139 >gi|239747104 PREDICTED: hypothetical protein XP_002344494 [Homo sapiens] Length = 173 Score = 199 bits (505), Expect = 4e-51 Identities = 94/133 (70%), Positives = 104/133 (78%), Gaps = 2/133 (1%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 MS VI +AC+GFFL Q W H GGQDKP SAWPSAVVP+GGHVTL C R GF IF+L Sbjct: 42 MSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHCRRGFNIFTL 101 Query: 61 YKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGL 120 YK+DGVPVPELYN+IFW S L+ PVTPAHAGTYRCRG HP SP EWSAPSNPLVI+VTG Sbjct: 102 YKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTG- 160 Query: 121 FGKPSLSAQPGPT 133 + + A P PT Sbjct: 161 -QRAPVWASPCPT 172 Score = 63.9 bits (154), Expect = 2e-10 Identities = 51/164 (31%), Positives = 70/164 (42%), Gaps = 22/164 (13%) Query: 83 GPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVT--GLF------------GKPSLSA 128 GP+T + A R P S + +P VI++ G F KP SA Sbjct: 16 GPLTTSSAPVSRAESLRPGSR-SCTMSMSPTVIILACLGFFLDQSVWAHVGGQDKPFCSA 74 Query: 129 QPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADFPLGPAT-- 186 P V G +V L C R F+++ L ++ P L + F F + P T Sbjct: 75 WPSAVVPQGGHVTLRCHCRRGFNIFTLYKKDGVPVPEL-----YNRIFWNSFLISPVTPA 129 Query: 187 HGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPS 230 H GTY C SP EWS PS+PL++ VTG + +SP S Sbjct: 130 HAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGQRAPVWASPCPTS 173 >gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B, member 3 isoform 2 [Homo sapiens] Length = 631 Score = 183 bits (464), Expect = 2e-46 Identities = 124/335 (37%), Positives = 170/335 (50%), Gaps = 23/335 (6%) Query: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGV-----PVPELYNKIFWK 78 G KP L V+ G +TL C S +G+ F LYKE P + + Sbjct: 220 GVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQA 279 Query: 79 SILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTG-LFGKPSLSAQPGPTVRTG 137 + +GPV+P++ G YRC G+H S EWSAPS+PL I++ G ++ SLSAQPGPTV +G Sbjct: 280 NFTLGPVSPSNGGQYRCYGAHNLSS-EWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASG 338 Query: 138 ENVALSCSSRSSFDMYHLSREGRAHEP-RLPAVPSVDGTFQADFPLGPAT--HGGTYTCF 194 ENV L C S FD + L++EG AH P RL ++ +QA+FP+ P T H GTY C+ Sbjct: 339 ENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAH-KYQAEFPMSPVTSAHAGTYRCY 397 Query: 195 SSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLHILIGTSVAIILFII 254 S +P+ S PS+PL + V+G+S SS PT P S G+ R+L +LIG SVA +L + Sbjct: 398 GSYSSNPHLLSHPSEPLELVVSGHSGGSSLPPTGPPSTPGLGRYLEVLIGVSVAFVLLLF 457 Query: 255 LFFFLL-----HCCCSNKKNAAVMDQGPAG-------DRTVNREDSDDQDPQEVTYAQLD 302 L FLL H Q PAG DR + R S D QE Sbjct: 458 LLLFLLLRRQRHSKHRTSDQRKTDFQRPAGAAETEPKDRGLLRRSSPAADVQEENLYAAV 517 Query: 303 HCVFTQTKITSPSQRPKAPPTDTTMYMELPNAKPR 337 ++ ++ SQ P Y + ++ PR Sbjct: 518 KDTQSEDRVELDSQSPHDEDPQAVTYAPVKHSSPR 552 Score = 130 bits (327), Expect = 2e-30 Identities = 77/214 (35%), Positives = 114/214 (53%), Gaps = 9/214 (4%) Query: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVPVP------ELYNKIFW 77 G KP LSA PS VV GG++TL C S+ G+ F L KE +P +L+++ F Sbjct: 119 GAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQ 178 Query: 78 KSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLFGKPSLSAQPGPTVRTG 137 +GPVTP+H + C + +P WS PS+PL I+ +G+ KPSL GP + G Sbjct: 179 ALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPG 238 Query: 138 ENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADFPLGPA--THGGTYTCFS 195 +++ L C S ++ + L +EG + P G QA+F LGP ++GG Y C+ Sbjct: 239 QSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYG 298 Query: 196 SLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEP 229 + H+ EWS PSDPL + + G + S +P Sbjct: 299 A-HNLSSEWSAPSDPLNILMAGQIYDTVSLSAQP 331 Score = 120 bits (302), Expect = 2e-27 Identities = 83/233 (35%), Positives = 117/233 (50%), Gaps = 17/233 (7%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 M+ + ++ C+G L G KP L A P +V+ G VT+ C+ + L Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRL 60 Query: 61 YKEDGVPVP-------ELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPL 113 +KE G P P E NK + + +T HAG YRC H S WS PS+PL Sbjct: 61 HKE-GSPEPLDRNNPLEPKNKARFS---IPSMTEHHAGRYRC---HYYSSAGWSEPSDPL 113 Query: 114 VIVVTGLFGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPR-LPAVPSV 172 +V+TG + KP+LSA P P V +G N+ L C S+ + + L +EG PR L + Sbjct: 114 EMVMTGAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLH 173 Query: 173 DGTFQADFPLGPAT--HGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSS 223 FQA FP+GP T H +TC+ ++P+ WS PSDPL + +G S S Sbjct: 174 SRGFQALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPS 226 Score = 51.6 bits (122), Expect = 1e-06 Identities = 37/116 (31%), Positives = 48/116 (41%), Gaps = 7/116 (6%) Query: 112 PLVIVVTGLFGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAH--EPRLPAV 169 P V G F KP+L A+PG + G V + C Y L +EG + P Sbjct: 17 PRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPLDRNNPLE 76 Query: 170 PSVDGTFQADFPLGPATHGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSS 225 P F P H G Y C + S WS+PSDPL + +TG S + S Sbjct: 77 PKNKARFS--IPSMTEHHAGRYRCH---YYSSAGWSEPSDPLEMVMTGAYSKPTLS 127 Score = 31.2 bits (69), Expect = 1.6 Identities = 15/52 (28%), Positives = 25/52 (48%) Query: 280 DRTVNREDSDDQDPQEVTYAQLDHCVFTQTKITSPSQRPKAPPTDTTMYMEL 331 DR ++ E + + Q+VTYAQL + P + PP + ++Y L Sbjct: 577 DRQMDTEAAASEASQDVTYAQLHSLTLRRKATEPPPSQEGEPPAEPSIYATL 628 >gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B, member 3 isoform 1 [Homo sapiens] Length = 632 Score = 181 bits (460), Expect = 7e-46 Identities = 133/391 (34%), Positives = 188/391 (48%), Gaps = 64/391 (16%) Query: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGV-----PVPELYNKIFWK 78 G KP L V+ G +TL C S +G+ F LYKE P + + Sbjct: 220 GVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQA 279 Query: 79 SILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTG-LFGKPSLSAQPGPTVRTG 137 + +GPV+P++ G YRC G+H S EWSAPS+PL I++ G ++ SLSAQPGPTV +G Sbjct: 280 NFTLGPVSPSNGGQYRCYGAHNLSS-EWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASG 338 Query: 138 ENVALSCSSRSSFDMYHLSREGRAHEP-RLPAVPSVDGTFQADFPLGPAT--HGGTYTCF 194 ENV L C S FD + L++EG AH P RL ++ +QA+FP+ P T H GTY C+ Sbjct: 339 ENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAH-KYQAEFPMSPVTSAHAGTYRCY 397 Query: 195 SSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLHILIGTSVAIILFII 254 S +P+ S PS+PL + V+G+S SS PT P S G+ R+L +LIG SVA +L + Sbjct: 398 GSYSSNPHLLSHPSEPLELVVSGHSGGSSLPPTGPPSTPGLGRYLEVLIGVSVAFVLLLF 457 Query: 255 LFFFLL-----HCCCSNKKNAAVMDQGPAG-------DRTVNREDS-------------- 288 L FLL H Q PAG DR + R S Sbjct: 458 LLLFLLLRRQRHSKHRTSDQRKTDFQRPAGAAETEPKDRGLLRRSSPAADVQEENLYAAV 517 Query: 289 -----------------DDQDPQEVTYAQLDHCVFTQTKITSPSQRPKAPPTDTTMYMEL 331 D+DPQ VTYA + H +SP + +PP +++ E Sbjct: 518 KDTQSEDRVELDSQQSPHDEDPQAVTYAPVKH--------SSPRREMASPP--SSLSGEF 567 Query: 332 PNAKPRSLSPAHKHHSQALRGSSRETTALSQ 362 + K R + + ++A + + +Q Sbjct: 568 LDTKDRQVEEDRQMDTEAAASEASQDVTYAQ 598 Score = 130 bits (327), Expect = 2e-30 Identities = 77/214 (35%), Positives = 114/214 (53%), Gaps = 9/214 (4%) Query: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVPVP------ELYNKIFW 77 G KP LSA PS VV GG++TL C S+ G+ F L KE +P +L+++ F Sbjct: 119 GAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQ 178 Query: 78 KSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLFGKPSLSAQPGPTVRTG 137 +GPVTP+H + C + +P WS PS+PL I+ +G+ KPSL GP + G Sbjct: 179 ALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPG 238 Query: 138 ENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADFPLGPA--THGGTYTCFS 195 +++ L C S ++ + L +EG + P G QA+F LGP ++GG Y C+ Sbjct: 239 QSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYG 298 Query: 196 SLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEP 229 + H+ EWS PSDPL + + G + S +P Sbjct: 299 A-HNLSSEWSAPSDPLNILMAGQIYDTVSLSAQP 331 Score = 120 bits (302), Expect = 2e-27 Identities = 83/233 (35%), Positives = 117/233 (50%), Gaps = 17/233 (7%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 M+ + ++ C+G L G KP L A P +V+ G VT+ C+ + L Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRL 60 Query: 61 YKEDGVPVP-------ELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPL 113 +KE G P P E NK + + +T HAG YRC H S WS PS+PL Sbjct: 61 HKE-GSPEPLDRNNPLEPKNKARFS---IPSMTEHHAGRYRC---HYYSSAGWSEPSDPL 113 Query: 114 VIVVTGLFGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPR-LPAVPSV 172 +V+TG + KP+LSA P P V +G N+ L C S+ + + L +EG PR L + Sbjct: 114 EMVMTGAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLH 173 Query: 173 DGTFQADFPLGPAT--HGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSS 223 FQA FP+GP T H +TC+ ++P+ WS PSDPL + +G S S Sbjct: 174 SRGFQALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPS 226 Score = 51.6 bits (122), Expect = 1e-06 Identities = 37/116 (31%), Positives = 48/116 (41%), Gaps = 7/116 (6%) Query: 112 PLVIVVTGLFGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAH--EPRLPAV 169 P V G F KP+L A+PG + G V + C Y L +EG + P Sbjct: 17 PRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPLDRNNPLE 76 Query: 170 PSVDGTFQADFPLGPATHGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSS 225 P F P H G Y C + S WS+PSDPL + +TG S + S Sbjct: 77 PKNKARFS--IPSMTEHHAGRYRCH---YYSSAGWSEPSDPLEMVMTGAYSKPTLS 127 Score = 31.2 bits (69), Expect = 1.6 Identities = 15/52 (28%), Positives = 25/52 (48%) Query: 280 DRTVNREDSDDQDPQEVTYAQLDHCVFTQTKITSPSQRPKAPPTDTTMYMEL 331 DR ++ E + + Q+VTYAQL + P + PP + ++Y L Sbjct: 578 DRQMDTEAAASEASQDVTYAQLHSLTLRRKATEPPPSQEGEPPAEPSIYATL 629 >gi|5803070 leukocyte immunoglobulin-like receptor, subfamily B, member 5 isoform 2 [Homo sapiens] Length = 590 Score = 177 bits (450), Expect = 1e-44 Identities = 125/370 (33%), Positives = 174/370 (47%), Gaps = 63/370 (17%) Query: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVPVPELYNK-----IFWK 78 G KP L +VV RGG +TL CRS +G+ IF LYKE + + + + Sbjct: 219 GVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQA 278 Query: 79 SILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLFGK-PSLSAQPGPTVRTG 137 + +GPV+ +H G YRC G+H SP WSAPS+PL I++ GL P+LS QPGP V +G Sbjct: 279 NFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVASG 337 Query: 138 ENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADFPLGPAT--HGGTYTCFS 195 ENV L C S D + L++EG AH P QA+F + P T GGTY C+S Sbjct: 338 ENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYS 397 Query: 196 SLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPT----------EPSSKT------GIRRHL 239 ++ PY S PS P + V+G S S SPT +P + T G+ RHL Sbjct: 398 AIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPGPEDQPLTPTGLDPQSGLGRHL 457 Query: 240 HILIGTSVA--IILFIILFFFLLHCCCSNKK----------------------------- 268 ++ G SVA ++LF++LF L H S + Sbjct: 458 GVVTGVSVAFVLLLFLLLFLLLRHRHQSKHRTSAHFYRPAGAAGPEPKDQGLQKRASPVA 517 Query: 269 -------NAAVMDQGPAGDRTVNREDSDDQDPQEVTYAQLDHCVFTQTKITSPSQRPKAP 321 NAAV D P ++ + + PQ+VTYAQL + P + + P Sbjct: 518 DIQEEILNAAVKDTQPKDGVEMDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQEREP 577 Query: 322 PTDTTMYMEL 331 P + ++Y L Sbjct: 578 PAEPSIYAPL 587 Score = 110 bits (276), Expect = 2e-24 Identities = 75/222 (33%), Positives = 110/222 (49%), Gaps = 8/222 (3%) Query: 28 KPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVPVPELYNKIFWKS-----ILM 82 +P L A PS VV GG+VTL C + G F L +E+ LY++ K + Sbjct: 123 EPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPV 182 Query: 83 GPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLFGKPSLSAQPGPTVRTGENVAL 142 GPVTP+ +RC + ++P WS PS+ L I+V G+ KPSL G V G ++ L Sbjct: 183 GPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTL 242 Query: 143 SCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADFPLGPA--THGGTYTCFSSLHDS 200 C S +D++ L +EG + G QA+F LGP +HGG Y C+ + + S Sbjct: 243 QCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLS 302 Query: 201 PYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLHIL 242 P WS PSDPL + + G + +P K ++ +L Sbjct: 303 P-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLL 343 Score = 100 bits (249), Expect = 2e-21 Identities = 75/238 (31%), Positives = 105/238 (44%), Gaps = 28/238 (11%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 M+L + + C+G + G KP L A P++V+ RG VTL C+ L + L Sbjct: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60 Query: 61 YKEDGVPVPELYNKIFWKSILMGPVTPA-------------HAGTYRCRGSHPRSPIEWS 107 KE G+P W P+ P AG YRC + +P WS Sbjct: 61 DKE-GLP---------WARKRQNPLEPGAKAKFHIPSTVYDSAGRYRC---YYETPAGWS 107 Query: 108 APSNPLVIVVTGLFGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLP 167 PS+PL +V TG + +P+L A P P V +G NV L C + + L E + L Sbjct: 108 EPSDPLELVATGFYAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLY 167 Query: 168 AVPSVDGTFQADFPLGPATHG--GTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSS 223 + G QA FP+GP T + C+ +P WS+PSD L + V G S S Sbjct: 168 SQKLPKGPSQALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPS 225 >gi|125987593 leukocyte immunoglobulin-like receptor, subfamily B, member 5 isoform 3 [Homo sapiens] Length = 491 Score = 177 bits (449), Expect = 1e-44 Identities = 125/371 (33%), Positives = 174/371 (46%), Gaps = 64/371 (17%) Query: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVPVPELYNK-----IFWK 78 G KP L +VV RGG +TL CRS +G+ IF LYKE + + + + Sbjct: 119 GVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQA 178 Query: 79 SILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLFGK-PSLSAQPGPTVRTG 137 + +GPV+ +H G YRC G+H SP WSAPS+PL I++ GL P+LS QPGP V +G Sbjct: 179 NFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVASG 237 Query: 138 ENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADFPLGPAT--HGGTYTCFS 195 ENV L C S D + L++EG AH P QA+F + P T GGTY C+S Sbjct: 238 ENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYS 297 Query: 196 SLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPT-----------EPSSKTGIR------RH 238 ++ PY S PS P + V+G S S SPT +P + TG+ RH Sbjct: 298 AIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLGRH 357 Query: 239 LHILIGTSVA--IILFIILFFFLLHCCCSNKK---------------------------- 268 L ++ G SVA ++LF++LF L H S + Sbjct: 358 LGVVTGVSVAFVLLLFLLLFLLLRHRHQSKHRTSAHFYRPAGAAGPEPKDQGLQKRASPV 417 Query: 269 --------NAAVMDQGPAGDRTVNREDSDDQDPQEVTYAQLDHCVFTQTKITSPSQRPKA 320 NAAV D P ++ + + PQ+VTYAQL + P + + Sbjct: 418 ADIQEEILNAAVKDTQPKDGVEMDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQERE 477 Query: 321 PPTDTTMYMEL 331 PP + ++Y L Sbjct: 478 PPAEPSIYAPL 488 Score = 108 bits (270), Expect = 8e-24 Identities = 80/257 (31%), Positives = 116/257 (45%), Gaps = 29/257 (11%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 M+L + + C+G + G KP L A P++V+ RG VTL C+ L + L Sbjct: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60 Query: 61 YKEDGVPVPELYNKIFWKSILMGPVTPA-------------HAGTYRCRGSHPRSPIEWS 107 KE G+P W P+ P AG YRC + +P WS Sbjct: 61 DKE-GLP---------WARKRQNPLEPGAKAKFHIPSTVYDSAGRYRC---YYETPAGWS 107 Query: 108 APSNPLVIVVTGLFGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLP 167 PS+PL +V TG+ KPSL G V G ++ L C S +D++ L +EG + Sbjct: 108 EPSDPLELVATGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGS 167 Query: 168 AVPSVDGTFQADFPLGPA--THGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSS 225 G QA+F LGP +HGG Y C+ + + SP WS PSDPL + + G + Sbjct: 168 GQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPDIPAL 226 Query: 226 PTEPSSKTGIRRHLHIL 242 +P K ++ +L Sbjct: 227 SVQPGPKVASGENVTLL 243 >gi|125987591 leukocyte immunoglobulin-like receptor, subfamily B, member 5 isoform 1 [Homo sapiens] Length = 591 Score = 177 bits (449), Expect = 1e-44 Identities = 125/371 (33%), Positives = 174/371 (46%), Gaps = 64/371 (17%) Query: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVPVPELYNK-----IFWK 78 G KP L +VV RGG +TL CRS +G+ IF LYKE + + + + Sbjct: 219 GVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQA 278 Query: 79 SILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLFGK-PSLSAQPGPTVRTG 137 + +GPV+ +H G YRC G+H SP WSAPS+PL I++ GL P+LS QPGP V +G Sbjct: 279 NFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVASG 337 Query: 138 ENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADFPLGPAT--HGGTYTCFS 195 ENV L C S D + L++EG AH P QA+F + P T GGTY C+S Sbjct: 338 ENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYS 397 Query: 196 SLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPT-----------EPSSKT------GIRRH 238 ++ PY S PS P + V+G S S SPT +P + T G+ RH Sbjct: 398 AIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLGRH 457 Query: 239 LHILIGTSVA--IILFIILFFFLLHCCCSNKK---------------------------- 268 L ++ G SVA ++LF++LF L H S + Sbjct: 458 LGVVTGVSVAFVLLLFLLLFLLLRHRHQSKHRTSAHFYRPAGAAGPEPKDQGLQKRASPV 517 Query: 269 --------NAAVMDQGPAGDRTVNREDSDDQDPQEVTYAQLDHCVFTQTKITSPSQRPKA 320 NAAV D P ++ + + PQ+VTYAQL + P + + Sbjct: 518 ADIQEEILNAAVKDTQPKDGVEMDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQERE 577 Query: 321 PPTDTTMYMEL 331 PP + ++Y L Sbjct: 578 PPAEPSIYAPL 588 Score = 110 bits (276), Expect = 2e-24 Identities = 75/222 (33%), Positives = 110/222 (49%), Gaps = 8/222 (3%) Query: 28 KPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVPVPELYNKIFWKS-----ILM 82 +P L A PS VV GG+VTL C + G F L +E+ LY++ K + Sbjct: 123 EPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPV 182 Query: 83 GPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLFGKPSLSAQPGPTVRTGENVAL 142 GPVTP+ +RC + ++P WS PS+ L I+V G+ KPSL G V G ++ L Sbjct: 183 GPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTL 242 Query: 143 SCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADFPLGPA--THGGTYTCFSSLHDS 200 C S +D++ L +EG + G QA+F LGP +HGG Y C+ + + S Sbjct: 243 QCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLS 302 Query: 201 PYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLHIL 242 P WS PSDPL + + G + +P K ++ +L Sbjct: 303 P-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLL 343 Score = 100 bits (249), Expect = 2e-21 Identities = 75/238 (31%), Positives = 105/238 (44%), Gaps = 28/238 (11%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 M+L + + C+G + G KP L A P++V+ RG VTL C+ L + L Sbjct: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60 Query: 61 YKEDGVPVPELYNKIFWKSILMGPVTPA-------------HAGTYRCRGSHPRSPIEWS 107 KE G+P W P+ P AG YRC + +P WS Sbjct: 61 DKE-GLP---------WARKRQNPLEPGAKAKFHIPSTVYDSAGRYRC---YYETPAGWS 107 Query: 108 APSNPLVIVVTGLFGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLP 167 PS+PL +V TG + +P+L A P P V +G NV L C + + L E + L Sbjct: 108 EPSDPLELVATGFYAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLY 167 Query: 168 AVPSVDGTFQADFPLGPATHG--GTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSS 223 + G QA FP+GP T + C+ +P WS+PSD L + V G S S Sbjct: 168 SQKLPKGPSQALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPS 225 >gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B, member 2 isoform 2 [Homo sapiens] Length = 597 Score = 171 bits (433), Expect = 1e-42 Identities = 123/377 (32%), Positives = 177/377 (46%), Gaps = 71/377 (18%) Query: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVPVPELYNK-----IFWK 78 G KP LS P VV G +TL C S +G+ F LYKE + +L + + Sbjct: 220 GVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQA 279 Query: 79 SILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTG-LFGKPSLSAQPGPTVRTG 137 + +GPV+ ++ G YRC G+H S E SAPS+PL I++TG + G P +S QPGPTV +G Sbjct: 280 NFTLGPVSRSYGGQYRCYGAHNLSS-ECSAPSDPLDILITGQIRGTPFISVQPGPTVASG 338 Query: 138 ENVALSCSSRSSFDMYHLSREGRAHEP-RLPAVPSVDGTFQADFPLGPAT--HGGTYTCF 194 ENV L C S F + L++ G A P RL ++ +QA+FP+ P T H GTY C+ Sbjct: 339 ENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYP-KYQAEFPMSPVTSAHAGTYRCY 397 Query: 195 SSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSS----------------KTGIRRH 238 SL+ PY S PS+PL + V+G S SS PT P S ++G+ RH Sbjct: 398 GSLNSDPYLLSHPSEPLELVVSGPSMGSSPPPTGPISTPGPEDQPLTPTGSDPQSGLGRH 457 Query: 239 LHILIGTSVAIILFIILFFFLL----------HCCCSNKK-------------------- 268 L ++IG VA++L ++L L H + +K Sbjct: 458 LGVVIGILVAVVLLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGLQ 517 Query: 269 --------------NAAVMDQGPAGDRTVNREDSDDQDPQEVTYAQLDHCVFTQTKITSP 314 AAV D P ++ + + PQ+VTYAQL + P Sbjct: 518 WRSSPAADAQEENLYAAVKDTQPEDGVEMDTRAAASEAPQDVTYAQLHSLTLRRKATEPP 577 Query: 315 SQRPKAPPTDTTMYMEL 331 + + PP + ++Y L Sbjct: 578 PSQEREPPAEPSIYATL 594 Score = 134 bits (337), Expect = 1e-31 Identities = 85/218 (38%), Positives = 113/218 (51%), Gaps = 17/218 (7%) Query: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVPVPELYNK--------- 74 G KP LSA PS VV GG VTL C S++ F F L KE P+ N Sbjct: 119 GAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSR 178 Query: 75 -IFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLFGKPSLSAQPGPT 133 IF +GPV+P ++RC G SP WS+PS+ L ++V G+ KPSLS QPGP Sbjct: 179 AIF----SVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPV 234 Query: 134 VRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADFPLGPA--THGGTY 191 V GE++ L C S +D + L +EG +LP G QA+F LGP ++GG Y Sbjct: 235 VAPGESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQY 294 Query: 192 TCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEP 229 C+ + H+ E S PSDPL + +TG + +P Sbjct: 295 RCYGA-HNLSSECSAPSDPLDILITGQIRGTPFISVQP 331 Score = 112 bits (280), Expect = 5e-25 Identities = 80/234 (34%), Positives = 114/234 (48%), Gaps = 15/234 (6%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 M+ +V + C+G L G KP L A P +V+ +G VTL C+ L + L Sbjct: 1 MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRL 60 Query: 61 YKEDGVPV------PELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLV 114 Y+E PEL + +T H G Y C+ S WS S+PLV Sbjct: 61 YREKKSASWITRIRPELVKN---GQFHIPSITWEHTGRYGCQYY---SRARWSELSDPLV 114 Query: 115 IVVTGLFGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPR-LPAVPSVD 173 +V+TG + KP+LSAQP P V +G V L C S+ +F + L +EG P+ L + P Sbjct: 115 LVMTGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHAR 174 Query: 174 GTFQADFPLGPAT--HGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSS 225 G+ +A F +GP + ++ C+ +SPY WS PSD L + V G S S S Sbjct: 175 GSSRAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLS 228 >gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B, member 2 isoform 1 [Homo sapiens] Length = 598 Score = 171 bits (432), Expect = 1e-42 Identities = 123/378 (32%), Positives = 177/378 (46%), Gaps = 72/378 (19%) Query: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVPVPELYNK-----IFWK 78 G KP LS P VV G +TL C S +G+ F LYKE + +L + + Sbjct: 220 GVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQA 279 Query: 79 SILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTG-LFGKPSLSAQPGPTVRTG 137 + +GPV+ ++ G YRC G+H S E SAPS+PL I++TG + G P +S QPGPTV +G Sbjct: 280 NFTLGPVSRSYGGQYRCYGAHNLSS-ECSAPSDPLDILITGQIRGTPFISVQPGPTVASG 338 Query: 138 ENVALSCSSRSSFDMYHLSREGRAHEP-RLPAVPSVDGTFQADFPLGPAT--HGGTYTCF 194 ENV L C S F + L++ G A P RL ++ +QA+FP+ P T H GTY C+ Sbjct: 339 ENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYP-KYQAEFPMSPVTSAHAGTYRCY 397 Query: 195 SSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSS-----------------KTGIRR 237 SL+ PY S PS+PL + V+G S SS PT P S ++G+ R Sbjct: 398 GSLNSDPYLLSHPSEPLELVVSGPSMGSSPPPTGPISTPAGPEDQPLTPTGSDPQSGLGR 457 Query: 238 HLHILIGTSVAIILFIILFFFLL----------HCCCSNKK------------------- 268 HL ++IG VA++L ++L L H + +K Sbjct: 458 HLGVVIGILVAVVLLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGL 517 Query: 269 ---------------NAAVMDQGPAGDRTVNREDSDDQDPQEVTYAQLDHCVFTQTKITS 313 AAV D P ++ + + PQ+VTYAQL + Sbjct: 518 QWRSSPAADAQEENLYAAVKDTQPEDGVEMDTRAAASEAPQDVTYAQLHSLTLRRKATEP 577 Query: 314 PSQRPKAPPTDTTMYMEL 331 P + + PP + ++Y L Sbjct: 578 PPSQEREPPAEPSIYATL 595 Score = 134 bits (337), Expect = 1e-31 Identities = 85/218 (38%), Positives = 113/218 (51%), Gaps = 17/218 (7%) Query: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVPVPELYNK--------- 74 G KP LSA PS VV GG VTL C S++ F F L KE P+ N Sbjct: 119 GAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSR 178 Query: 75 -IFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLFGKPSLSAQPGPT 133 IF +GPV+P ++RC G SP WS+PS+ L ++V G+ KPSLS QPGP Sbjct: 179 AIF----SVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPV 234 Query: 134 VRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADFPLGPA--THGGTY 191 V GE++ L C S +D + L +EG +LP G QA+F LGP ++GG Y Sbjct: 235 VAPGESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQY 294 Query: 192 TCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEP 229 C+ + H+ E S PSDPL + +TG + +P Sbjct: 295 RCYGA-HNLSSECSAPSDPLDILITGQIRGTPFISVQP 331 Score = 112 bits (280), Expect = 5e-25 Identities = 80/234 (34%), Positives = 114/234 (48%), Gaps = 15/234 (6%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 M+ +V + C+G L G KP L A P +V+ +G VTL C+ L + L Sbjct: 1 MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRL 60 Query: 61 YKEDGVPV------PELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLV 114 Y+E PEL + +T H G Y C+ S WS S+PLV Sbjct: 61 YREKKSASWITRIRPELVKN---GQFHIPSITWEHTGRYGCQYY---SRARWSELSDPLV 114 Query: 115 IVVTGLFGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPR-LPAVPSVD 173 +V+TG + KP+LSAQP P V +G V L C S+ +F + L +EG P+ L + P Sbjct: 115 LVMTGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHAR 174 Query: 174 GTFQADFPLGPAT--HGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSS 225 G+ +A F +GP + ++ C+ +SPY WS PSD L + V G S S S Sbjct: 175 GSSRAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLS 228 >gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B, member 1 isoform 4 [Homo sapiens] Length = 651 Score = 164 bits (414), Expect = 2e-40 Identities = 118/353 (33%), Positives = 164/353 (46%), Gaps = 40/353 (11%) Query: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVPVPELYNK-----IFWK 78 G KP LS P +V +TL C S G+ F LYK+ +L + Sbjct: 221 GVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQA 280 Query: 79 SILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLF-GKPSLSAQPGPTVRTG 137 + +GPV+ ++ G YRC G+H S EWSAPS+PL I++ G F + SLS QPGPTV +G Sbjct: 281 NFTLGPVSRSYGGQYRCYGAHNLSS-EWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASG 339 Query: 138 ENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADFPLGPAT--HGGTYTCFS 195 ENV L C S+ + L++EG A +P +QA+FP+GP T H GTY C+ Sbjct: 340 ENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYG 399 Query: 196 SLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSS----------------KTGIRRHL 239 S PY + PSDPL + V+G S SS T P+S ++G+ RHL Sbjct: 400 SQSSKPYLLTHPSDPLELVVSGPSGGPSSPTTGPTSTSGPEDQPLTPTGSDPQSGLGRHL 459 Query: 240 HILIGTSVAIILFIILFFFLL----------HCCCSNKKNAAVMDQGPAG----DRTVNR 285 ++IG VA+IL ++L L H + +K G G DR + Sbjct: 460 GVVIGILVAVILLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGLQW 519 Query: 286 EDSDDQDPQEVT-YAQLDHCVFTQTKITSPSQRPKAPPTDTTMYMELPNAKPR 337 S D QE YA + H Q P Y E+ +++PR Sbjct: 520 RSSPAADAQEENLYAAVKHTQPEDGVEMDTRQSPHDEDPQAVTYAEVKHSRPR 572 Score = 131 bits (330), Expect = 9e-31 Identities = 83/218 (38%), Positives = 111/218 (50%), Gaps = 17/218 (7%) Query: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVPVPELYNK--------- 74 G KP LSA PS VV GG+V L C S++ F FSL KE P+ N Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179 Query: 75 -IFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLFGKPSLSAQPGPT 133 IF +GPV+P+ YRC SP EWS PS+ L ++V G+ KPSLS QPGP Sbjct: 180 AIF----SVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPI 235 Query: 134 VRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADFPLGPA--THGGTY 191 V E + L C S + ++ + L ++G +L G QA+F LGP ++GG Y Sbjct: 236 VAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQY 295 Query: 192 TCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEP 229 C+ + H+ EWS PSDPL + + G S +P Sbjct: 296 RCYGA-HNLSSEWSAPSDPLDILIAGQFYDRVSLSVQP 332 Score = 116 bits (291), Expect = 3e-26 Identities = 85/260 (32%), Positives = 126/260 (48%), Gaps = 9/260 (3%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 M+ ++ + C+G L G KP L A P +V+ +G VTL C+ + L Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60 Query: 61 YKEDGVP--VPELYNKIFWKSILMGP-VTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVV 117 Y+E + + ++ K P +T HAG YRC + S S+PL +VV Sbjct: 61 YREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCY--YGSDTAGRSESSDPLELVV 118 Query: 118 TGLFGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPR-LPAVPSVDGTF 176 TG + KP+LSAQP P V +G NV L C S+ +FD + L +EG P+ L + P G+ Sbjct: 119 TGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSS 178 Query: 177 QADFPLGPATHGGT--YTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTG 234 +A F +GP + Y C++ +SPYEWS PSD L + V G S S S +P Sbjct: 179 RAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLS-VQPGPIVA 237 Query: 235 IRRHLHILIGTSVAIILFII 254 L + G+ F++ Sbjct: 238 PEETLTLQCGSDAGYNRFVL 257 Score = 30.8 bits (68), Expect = 2.1 Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 2/59 (3%) Query: 274 DQGPAGDRTVNREDSDDQDPQEVTYAQLDHCVFTQTKITSPSQRPKAP-PTDTTMYMEL 331 D+ DR ++ E + + PQ+VTYAQL H + + + T P + P P ++Y L Sbjct: 591 DRQAEEDRQMDTEAAASEAPQDVTYAQL-HSLTLRREATEPPPSQEGPSPAVPSIYATL 648 >gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B, member 1 isoform 2 [Homo sapiens] Length = 652 Score = 163 bits (413), Expect = 2e-40 Identities = 118/354 (33%), Positives = 164/354 (46%), Gaps = 41/354 (11%) Query: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVPVPELYNK-----IFWK 78 G KP LS P +V +TL C S G+ F LYK+ +L + Sbjct: 221 GVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQA 280 Query: 79 SILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLF-GKPSLSAQPGPTVRTG 137 + +GPV+ ++ G YRC G+H S EWSAPS+PL I++ G F + SLS QPGPTV +G Sbjct: 281 NFTLGPVSRSYGGQYRCYGAHNLSS-EWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASG 339 Query: 138 ENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADFPLGPAT--HGGTYTCFS 195 ENV L C S+ + L++EG A +P +QA+FP+GP T H GTY C+ Sbjct: 340 ENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYG 399 Query: 196 SLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSS-----------------KTGIRRH 238 S PY + PSDPL + V+G S SS T P+S ++G+ RH Sbjct: 400 SQSSKPYLLTHPSDPLELVVSGPSGGPSSPTTGPTSTSAGPEDQPLTPTGSDPQSGLGRH 459 Query: 239 LHILIGTSVAIILFIILFFFLL----------HCCCSNKKNAAVMDQGPAG----DRTVN 284 L ++IG VA+IL ++L L H + +K G G DR + Sbjct: 460 LGVVIGILVAVILLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGLQ 519 Query: 285 REDSDDQDPQEVT-YAQLDHCVFTQTKITSPSQRPKAPPTDTTMYMELPNAKPR 337 S D QE YA + H Q P Y E+ +++PR Sbjct: 520 WRSSPAADAQEENLYAAVKHTQPEDGVEMDTRQSPHDEDPQAVTYAEVKHSRPR 573 Score = 132 bits (332), Expect = 5e-31 Identities = 103/334 (30%), Positives = 148/334 (44%), Gaps = 30/334 (8%) Query: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVPVPELYNK--------- 74 G KP LSA PS VV GG+V L C S++ F FSL KE P+ N Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179 Query: 75 -IFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLFGKPSLSAQPGPT 133 IF +GPV+P+ YRC SP EWS PS+ L ++V G+ KPSLS QPGP Sbjct: 180 AIF----SVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPI 235 Query: 134 VRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADFPLGPA--THGGTY 191 V E + L C S + ++ + L ++G +L G QA+F LGP ++GG Y Sbjct: 236 VAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQY 295 Query: 192 TCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLHILIGTSVAIIL 251 C+ + H+ EWS PSDPL + + G S +P ++ +L + + Sbjct: 296 RCYGA-HNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQT 354 Query: 252 FIILFF------FLLHCCCSNKKNAAVMDQGP---AGDRTVNREDSDDQDPQEVTYAQLD 302 F++ + L ++K A GP A T S P +T+ Sbjct: 355 FLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDP 414 Query: 303 HCVFTQTKITSPSQRPKAPPTDTTMYMELPNAKP 336 + ++ PS P +P T T P +P Sbjct: 415 ----LELVVSGPSGGPSSPTTGPTSTSAGPEDQP 444 Score = 116 bits (291), Expect = 3e-26 Identities = 85/260 (32%), Positives = 126/260 (48%), Gaps = 9/260 (3%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 M+ ++ + C+G L G KP L A P +V+ +G VTL C+ + L Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60 Query: 61 YKEDGVP--VPELYNKIFWKSILMGP-VTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVV 117 Y+E + + ++ K P +T HAG YRC + S S+PL +VV Sbjct: 61 YREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCY--YGSDTAGRSESSDPLELVV 118 Query: 118 TGLFGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPR-LPAVPSVDGTF 176 TG + KP+LSAQP P V +G NV L C S+ +FD + L +EG P+ L + P G+ Sbjct: 119 TGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSS 178 Query: 177 QADFPLGPATHGGT--YTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTG 234 +A F +GP + Y C++ +SPYEWS PSD L + V G S S S +P Sbjct: 179 RAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLS-VQPGPIVA 237 Query: 235 IRRHLHILIGTSVAIILFII 254 L + G+ F++ Sbjct: 238 PEETLTLQCGSDAGYNRFVL 257 Score = 30.8 bits (68), Expect = 2.1 Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 2/59 (3%) Query: 274 DQGPAGDRTVNREDSDDQDPQEVTYAQLDHCVFTQTKITSPSQRPKAP-PTDTTMYMEL 331 D+ DR ++ E + + PQ+VTYAQL H + + + T P + P P ++Y L Sbjct: 592 DRQAEEDRQMDTEAAASEAPQDVTYAQL-HSLTLRREATEPPPSQEGPSPAVPSIYATL 649 >gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B, member 1 isoform 1 [Homo sapiens] Length = 650 Score = 163 bits (412), Expect = 3e-40 Identities = 117/353 (33%), Positives = 167/353 (47%), Gaps = 41/353 (11%) Query: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVPVPELYNK-----IFWK 78 G KP LS P +V +TL C S G+ F LYK+ +L + Sbjct: 221 GVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQA 280 Query: 79 SILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLF-GKPSLSAQPGPTVRTG 137 + +GPV+ ++ G YRC G+H S EWSAPS+PL I++ G F + SLS QPGPTV +G Sbjct: 281 NFTLGPVSRSYGGQYRCYGAHNLSS-EWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASG 339 Query: 138 ENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADFPLGPAT--HGGTYTCFS 195 ENV L C S+ + L++EG A +P +QA+FP+GP T H GTY C+ Sbjct: 340 ENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYG 399 Query: 196 SLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSS----------------KTGIRRHL 239 S PY + PSDPL + V+G S SS T P+S ++G+ RHL Sbjct: 400 SQSSKPYLLTHPSDPLELVVSGPSGGPSSPTTGPTSTSGPEDQPLTPTGSDPQSGLGRHL 459 Query: 240 HILIGTSVAIILFIILFFFLL----------HCCCSNKKNAAVMDQGPAG----DRTVNR 285 ++IG VA+IL ++L L H + +K G G DR + Sbjct: 460 GVVIGILVAVILLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGLQW 519 Query: 286 EDSDDQDPQEVT-YAQLDHCVFTQTKITSPSQRPKAPPTDTTMYMELPNAKPR 337 S D QE YA + H + + ++ P Y E+ +++PR Sbjct: 520 RSSPAADAQEENLYAAVKH-TQPEDGVEMDTRSPHDEDPQAVTYAEVKHSRPR 571 Score = 131 bits (330), Expect = 9e-31 Identities = 83/218 (38%), Positives = 111/218 (50%), Gaps = 17/218 (7%) Query: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVPVPELYNK--------- 74 G KP LSA PS VV GG+V L C S++ F FSL KE P+ N Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179 Query: 75 -IFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLFGKPSLSAQPGPT 133 IF +GPV+P+ YRC SP EWS PS+ L ++V G+ KPSLS QPGP Sbjct: 180 AIF----SVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPI 235 Query: 134 VRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADFPLGPA--THGGTY 191 V E + L C S + ++ + L ++G +L G QA+F LGP ++GG Y Sbjct: 236 VAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQY 295 Query: 192 TCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEP 229 C+ + H+ EWS PSDPL + + G S +P Sbjct: 296 RCYGA-HNLSSEWSAPSDPLDILIAGQFYDRVSLSVQP 332 Score = 116 bits (291), Expect = 3e-26 Identities = 85/260 (32%), Positives = 126/260 (48%), Gaps = 9/260 (3%) Query: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 M+ ++ + C+G L G KP L A P +V+ +G VTL C+ + L Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60 Query: 61 YKEDGVP--VPELYNKIFWKSILMGP-VTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVV 117 Y+E + + ++ K P +T HAG YRC + S S+PL +VV Sbjct: 61 YREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCY--YGSDTAGRSESSDPLELVV 118 Query: 118 TGLFGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPR-LPAVPSVDGTF 176 TG + KP+LSAQP P V +G NV L C S+ +FD + L +EG P+ L + P G+ Sbjct: 119 TGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSS 178 Query: 177 QADFPLGPATHGGT--YTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTG 234 +A F +GP + Y C++ +SPYEWS PSD L + V G S S S +P Sbjct: 179 RAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLS-VQPGPIVA 237 Query: 235 IRRHLHILIGTSVAIILFII 254 L + G+ F++ Sbjct: 238 PEETLTLQCGSDAGYNRFVL 257 Score = 30.8 bits (68), Expect = 2.1 Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 2/59 (3%) Query: 274 DQGPAGDRTVNREDSDDQDPQEVTYAQLDHCVFTQTKITSPSQRPKAP-PTDTTMYMEL 331 D+ DR ++ E + + PQ+VTYAQL H + + + T P + P P ++Y L Sbjct: 590 DRQAEEDRQMDTEAAASEAPQDVTYAQL-HSLTLRREATEPPPSQEGPSPAVPSIYATL 647 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.132 0.411 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,115,252 Number of Sequences: 37866 Number of extensions: 906125 Number of successful extensions: 4459 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 85 Number of HSP's successfully gapped in prelim test: 74 Number of HSP's that attempted gapping in prelim test: 3685 Number of HSP's gapped (non-prelim): 332 length of query: 375 length of database: 18,247,518 effective HSP length: 104 effective length of query: 271 effective length of database: 14,309,454 effective search space: 3877862034 effective search space used: 3877862034 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.