Guide to the Human Genome
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Search of human proteins with 61835134

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|61835134 ADP-ribosyltransferase 4 precursor [Homo sapiens]
         (314 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|61835134 ADP-ribosyltransferase 4 precursor [Homo sapiens]         639   0.0  
gi|158634472 ADP-ribosyltransferase 1 [Homo sapiens]                  142   5e-34
gi|118640870 ADP-ribosyltransferase 5 precursor [Homo sapiens]        122   4e-28
gi|30089992 ADP-ribosyltransferase 5 precursor [Homo sapiens]         122   4e-28
gi|194097382 ADP-ribosyltransferase 3 isoform c [Homo sapiens]         80   2e-15
gi|194097380 ADP-ribosyltransferase 3 isoform a [Homo sapiens]         80   2e-15
gi|21361167 ADP-ribosyltransferase 3 isoform b [Homo sapiens]          80   2e-15
gi|167614502 protein phosphatase 1, regulatory (inhibitor) subun...    32   0.73 
gi|45580742 dehydrodolichyl diphosphate synthase isoform a [Homo...    29   6.2  

>gi|61835134 ADP-ribosyltransferase 4 precursor [Homo sapiens]
          Length = 314

 Score =  639 bits (1649), Expect = 0.0
 Identities = 314/314 (100%), Positives = 314/314 (100%)

Query: 1   MGPLINRCKKILLPTTVPPATMRIWLLGGLLPFLLLLSGLQRPTEGSEVAIKIDFDFAPG 60
           MGPLINRCKKILLPTTVPPATMRIWLLGGLLPFLLLLSGLQRPTEGSEVAIKIDFDFAPG
Sbjct: 1   MGPLINRCKKILLPTTVPPATMRIWLLGGLLPFLLLLSGLQRPTEGSEVAIKIDFDFAPG 60

Query: 61  SFDDQYQGCSKQVMEKLTQGDYFTKDIEAQKNYFRMWQKAHLAWLNQGKVLPQNMTTTHA 120
           SFDDQYQGCSKQVMEKLTQGDYFTKDIEAQKNYFRMWQKAHLAWLNQGKVLPQNMTTTHA
Sbjct: 61  SFDDQYQGCSKQVMEKLTQGDYFTKDIEAQKNYFRMWQKAHLAWLNQGKVLPQNMTTTHA 120

Query: 121 VAILFYTLNSNVHSDFTRAMASVARTPQQYERSFHFKYLHYYLTSAIQLLRKDSIMENGT 180
           VAILFYTLNSNVHSDFTRAMASVARTPQQYERSFHFKYLHYYLTSAIQLLRKDSIMENGT
Sbjct: 121 VAILFYTLNSNVHSDFTRAMASVARTPQQYERSFHFKYLHYYLTSAIQLLRKDSIMENGT 180

Query: 181 LCYEVHYRTKDVHFNAYTGATIRFGQFLSTSLLKEEAQEFGNQTLFTIFTCLGAPVQYFS 240
           LCYEVHYRTKDVHFNAYTGATIRFGQFLSTSLLKEEAQEFGNQTLFTIFTCLGAPVQYFS
Sbjct: 181 LCYEVHYRTKDVHFNAYTGATIRFGQFLSTSLLKEEAQEFGNQTLFTIFTCLGAPVQYFS 240

Query: 241 LKKEVLIPPYELFKVINMSYHPRGDWLQLRSTGNLSTYNCQLLKASSKKCIPDPIAIASL 300
           LKKEVLIPPYELFKVINMSYHPRGDWLQLRSTGNLSTYNCQLLKASSKKCIPDPIAIASL
Sbjct: 241 LKKEVLIPPYELFKVINMSYHPRGDWLQLRSTGNLSTYNCQLLKASSKKCIPDPIAIASL 300

Query: 301 SFLTSVIIFSKSRV 314
           SFLTSVIIFSKSRV
Sbjct: 301 SFLTSVIIFSKSRV 314


>gi|158634472 ADP-ribosyltransferase 1 [Homo sapiens]
          Length = 327

 Score =  142 bits (357), Expect = 5e-34
 Identities = 95/261 (36%), Positives = 129/261 (49%), Gaps = 25/261 (9%)

Query: 52  KIDFDFAPGSFDDQYQGCSKQVMEKLTQGDYFTKDIEAQKNYFRMWQKAHLAWLNQGKVL 111
           +I  D A  SFDDQY GC+  +   L   D    + +A + Y   W  A   W  +    
Sbjct: 36  EIQLDMALASFDDQYAGCAAAMTAALP--DLNHTEFQANQVYADSWTLASSQWQERQARW 93

Query: 112 PQ-------------NMTTTHAVAILFYTLNSNVHSDFTRAMASVARTPQQYERSFHFKY 158
           P+                  H VA+L YT NS +H +F  A+    R+   Y   F FK 
Sbjct: 94  PEWSLSPTRPSPPPLGFRDEHGVALLAYTANSPLHKEFNAAVREAGRSRAHYLHHFSFKT 153

Query: 159 LHYYLTSAIQLLRKDSIMENGTLCYEVHYRTKDVHFN-AYTGATIRFGQFLSTSLLKEEA 217
           LH+ LT A+QLL      +    C++V      + F  A   AT+R G F S SL    A
Sbjct: 154 LHFLLTEALQLLGSG---QRPPRCHQVFRGVHGLRFRPAGPRATVRLGGFASASLKHVAA 210

Query: 218 QEFGNQTLFTIFTCLGAPVQ---YFSLKKEVLIPPYELFKVINMSYHPRGD-WLQLRSTG 273
           Q+FG  T F I+TCLGAP++   +F  ++EVLIPP+E F+VIN S   +G   + LR+ G
Sbjct: 211 QQFGEDTFFGIWTCLGAPIKGYSFFPGEEEVLIPPFETFQVINASRLAQGPARIYLRALG 270

Query: 274 NLSTYNCQLLKASSKKCIPDP 294
             STYNC+ +K   KKC   P
Sbjct: 271 KHSTYNCEYIK--DKKCKSGP 289


>gi|118640870 ADP-ribosyltransferase 5 precursor [Homo sapiens]
          Length = 291

 Score =  122 bits (306), Expect = 4e-28
 Identities = 92/281 (32%), Positives = 140/281 (49%), Gaps = 16/281 (5%)

Query: 30  LLPFLLLLSGLQRPTEGSEVAIKIDFDFAPGSFDDQYQGCSKQVMEKLTQGDYFTKDIEA 89
           L   ++ L  L   T  ++    +    AP +FDD Y GC++++ EK        K+  A
Sbjct: 3   LAALMIALGSLGLHTWQAQAVPILPLGLAPDTFDDTYVGCAEEMEEKAAP---LLKEEMA 59

Query: 90  QKNYFR-MWQKAHLAWLNQ--GKVLPQNMTTTHAVAILFYTLNSN-VHSDFTRAMASVAR 145
                R  W+ A   W ++  G  LP      + +AI+ YT +SN ++ +  +A+ +   
Sbjct: 60  HHALLRESWEAAQETWEDKRRGLTLPPGFKAQNGIAIMVYTNSSNTLYWELNQAVRTGGG 119

Query: 146 TPQQYERSFHFKYLHYYLTSAIQLLRKDSIMENGTLCYEVHYR-TKDVHFNAYT-GATIR 203
           + + Y R F FK LH+YL  A+QLLR       G    EV +R    + F     G ++R
Sbjct: 120 SRELYMRHFPFKALHFYLIRALQLLRGSGGCSRGP--GEVVFRGVGSLRFEPKRLGDSVR 177

Query: 204 FGQFLSTSLLKEEAQEFGNQTLFTIFTCLGAPVQYFSL---KKEVLIPPYELFKVINMSY 260
            GQF S+SL K  A  FGN TLF++ TC GAP+Q FS+   ++EVLIPP+E+F V   S 
Sbjct: 178 LGQFASSSLDKAVAHRFGNATLFSLTTCFGAPIQAFSVFPKEREVLIPPHEVFLVTRFSQ 237

Query: 261 HPRGDWLQLRS-TGNLSTYNCQLLKASSKK-CIPDPIAIAS 299
                 + L S     S +NC  L    ++ C+  P A+ +
Sbjct: 238 DGAQSLVTLWSYNQTCSHFNCAYLGGEKRRGCVSAPGALGT 278


>gi|30089992 ADP-ribosyltransferase 5 precursor [Homo sapiens]
          Length = 291

 Score =  122 bits (306), Expect = 4e-28
 Identities = 92/281 (32%), Positives = 140/281 (49%), Gaps = 16/281 (5%)

Query: 30  LLPFLLLLSGLQRPTEGSEVAIKIDFDFAPGSFDDQYQGCSKQVMEKLTQGDYFTKDIEA 89
           L   ++ L  L   T  ++    +    AP +FDD Y GC++++ EK        K+  A
Sbjct: 3   LAALMIALGSLGLHTWQAQAVPILPLGLAPDTFDDTYVGCAEEMEEKAAP---LLKEEMA 59

Query: 90  QKNYFR-MWQKAHLAWLNQ--GKVLPQNMTTTHAVAILFYTLNSN-VHSDFTRAMASVAR 145
                R  W+ A   W ++  G  LP      + +AI+ YT +SN ++ +  +A+ +   
Sbjct: 60  HHALLRESWEAAQETWEDKRRGLTLPPGFKAQNGIAIMVYTNSSNTLYWELNQAVRTGGG 119

Query: 146 TPQQYERSFHFKYLHYYLTSAIQLLRKDSIMENGTLCYEVHYR-TKDVHFNAYT-GATIR 203
           + + Y R F FK LH+YL  A+QLLR       G    EV +R    + F     G ++R
Sbjct: 120 SRELYMRHFPFKALHFYLIRALQLLRGSGGCSRGP--GEVVFRGVGSLRFEPKRLGDSVR 177

Query: 204 FGQFLSTSLLKEEAQEFGNQTLFTIFTCLGAPVQYFSL---KKEVLIPPYELFKVINMSY 260
            GQF S+SL K  A  FGN TLF++ TC GAP+Q FS+   ++EVLIPP+E+F V   S 
Sbjct: 178 LGQFASSSLDKAVAHRFGNATLFSLTTCFGAPIQAFSVFPKEREVLIPPHEVFLVTRFSQ 237

Query: 261 HPRGDWLQLRS-TGNLSTYNCQLLKASSKK-CIPDPIAIAS 299
                 + L S     S +NC  L    ++ C+  P A+ +
Sbjct: 238 DGAQSLVTLWSYNQTCSHFNCAYLGGEKRRGCVSAPGALGT 278


>gi|194097382 ADP-ribosyltransferase 3 isoform c [Homo sapiens]
          Length = 367

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 66/244 (27%), Positives = 105/244 (43%), Gaps = 13/244 (5%)

Query: 56  DFAPGSFDDQYQGCSKQVMEKLTQGDYFTKDIEAQKNYFRMWQKAHLAWLNQGK--VLPQ 113
           D A  +FDD+Y  C+ ++  K        ++  + +    +W+ A   W  +     LP 
Sbjct: 30  DMADNAFDDEYLKCTDRMEIKYVP-QLLKEEKASHQQLDTVWENAKAKWAARKTQIFLPM 88

Query: 114 NMTTTHAVAILFYTLNSNVHSDF----TRAMASVARTPQQYERSFHFKYLHYYLTSAIQL 169
           N    H +A++ Y   +   + F    + A+    ++ + Y   F FK  H+YLT A+QL
Sbjct: 89  NFKDNHGIALMAYISEAQEQTPFYHLFSEAVKMAGQSREDYIYGFQFKAFHFYLTRALQL 148

Query: 170 LRKDSIMENGTLCYEVHYRTKDVHFNAYTGATIRFGQFLSTSLLKEEAQEFGNQTLFTIF 229
           LRK     + T+ Y     T    F     A  RFG F      K +A      T+ +I+
Sbjct: 149 LRKPCEASSKTVVYRTSQGT-SFTFGGLNQA--RFGHFTLAYSAKPQAAN-DQLTVLSIY 204

Query: 230 TCLGAPVQYFSLKKEVLIPPYELFKVINMSYHPRGDWLQLRSTG-NLSTYNCQLLKA-SS 287
           TCLG  ++ F  K+   I    L +V  +S    G+ L L+S     S Y C  L    +
Sbjct: 205 TCLGVDIENFLDKESERITLIPLNEVFQVSQEGAGNNLILQSINKTCSHYECAFLGGLKT 264

Query: 288 KKCI 291
           + CI
Sbjct: 265 ENCI 268


>gi|194097380 ADP-ribosyltransferase 3 isoform a [Homo sapiens]
          Length = 389

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 66/244 (27%), Positives = 105/244 (43%), Gaps = 13/244 (5%)

Query: 56  DFAPGSFDDQYQGCSKQVMEKLTQGDYFTKDIEAQKNYFRMWQKAHLAWLNQGK--VLPQ 113
           D A  +FDD+Y  C+ ++  K        ++  + +    +W+ A   W  +     LP 
Sbjct: 30  DMADNAFDDEYLKCTDRMEIKYVP-QLLKEEKASHQQLDTVWENAKAKWAARKTQIFLPM 88

Query: 114 NMTTTHAVAILFYTLNSNVHSDF----TRAMASVARTPQQYERSFHFKYLHYYLTSAIQL 169
           N    H +A++ Y   +   + F    + A+    ++ + Y   F FK  H+YLT A+QL
Sbjct: 89  NFKDNHGIALMAYISEAQEQTPFYHLFSEAVKMAGQSREDYIYGFQFKAFHFYLTRALQL 148

Query: 170 LRKDSIMENGTLCYEVHYRTKDVHFNAYTGATIRFGQFLSTSLLKEEAQEFGNQTLFTIF 229
           LRK     + T+ Y     T    F     A  RFG F      K +A      T+ +I+
Sbjct: 149 LRKPCEASSKTVVYRTSQGT-SFTFGGLNQA--RFGHFTLAYSAKPQAAN-DQLTVLSIY 204

Query: 230 TCLGAPVQYFSLKKEVLIPPYELFKVINMSYHPRGDWLQLRSTG-NLSTYNCQLLKA-SS 287
           TCLG  ++ F  K+   I    L +V  +S    G+ L L+S     S Y C  L    +
Sbjct: 205 TCLGVDIENFLDKESERITLIPLNEVFQVSQEGAGNNLILQSINKTCSHYECAFLGGLKT 264

Query: 288 KKCI 291
           + CI
Sbjct: 265 ENCI 268


>gi|21361167 ADP-ribosyltransferase 3 isoform b [Homo sapiens]
          Length = 378

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 66/244 (27%), Positives = 105/244 (43%), Gaps = 13/244 (5%)

Query: 56  DFAPGSFDDQYQGCSKQVMEKLTQGDYFTKDIEAQKNYFRMWQKAHLAWLNQGK--VLPQ 113
           D A  +FDD+Y  C+ ++  K        ++  + +    +W+ A   W  +     LP 
Sbjct: 30  DMADNAFDDEYLKCTDRMEIKYVP-QLLKEEKASHQQLDTVWENAKAKWAARKTQIFLPM 88

Query: 114 NMTTTHAVAILFYTLNSNVHSDF----TRAMASVARTPQQYERSFHFKYLHYYLTSAIQL 169
           N    H +A++ Y   +   + F    + A+    ++ + Y   F FK  H+YLT A+QL
Sbjct: 89  NFKDNHGIALMAYISEAQEQTPFYHLFSEAVKMAGQSREDYIYGFQFKAFHFYLTRALQL 148

Query: 170 LRKDSIMENGTLCYEVHYRTKDVHFNAYTGATIRFGQFLSTSLLKEEAQEFGNQTLFTIF 229
           LRK     + T+ Y     T    F     A  RFG F      K +A      T+ +I+
Sbjct: 149 LRKPCEASSKTVVYRTSQGT-SFTFGGLNQA--RFGHFTLAYSAKPQAAN-DQLTVLSIY 204

Query: 230 TCLGAPVQYFSLKKEVLIPPYELFKVINMSYHPRGDWLQLRSTG-NLSTYNCQLLKA-SS 287
           TCLG  ++ F  K+   I    L +V  +S    G+ L L+S     S Y C  L    +
Sbjct: 205 TCLGVDIENFLDKESERITLIPLNEVFQVSQEGAGNNLILQSINKTCSHYECAFLGGLKT 264

Query: 288 KKCI 291
           + CI
Sbjct: 265 ENCI 268


>gi|167614502 protein phosphatase 1, regulatory (inhibitor) subunit 3A
            [Homo sapiens]
          Length = 1122

 Score = 32.0 bits (71), Expect = 0.73
 Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 2/65 (3%)

Query: 197  YTGATIRFGQFLSTSLLKEEAQEFGNQTLFTIFTCLGAPVQYFSLKKEVLIPPYELFKVI 256
            YT          STSL  EE+Q  GN++LF+ +T   + + YF L    LI  Y    +I
Sbjct: 1039 YTSGEKESDSSASTSLPVEESQAQGNESLFSKYT--NSKIPYFLLFLIFLITVYHYDLMI 1096

Query: 257  NMSYH 261
             ++++
Sbjct: 1097 GLTFY 1101


>gi|45580742 dehydrodolichyl diphosphate synthase isoform a [Homo
           sapiens]
          Length = 334

 Score = 28.9 bits (63), Expect = 6.2
 Identities = 19/65 (29%), Positives = 30/65 (46%)

Query: 88  EAQKNYFRMWQKAHLAWLNQGKVLPQNMTTTHAVAILFYTLNSNVHSDFTRAMASVARTP 147
           E + + F +WQ +H   + Q  + P+        AIL + +N +V     R M +  R  
Sbjct: 209 EVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQMNHSVLQQKARDMYAEERKR 268

Query: 148 QQYER 152
           QQ ER
Sbjct: 269 QQLER 273


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,924,030
Number of Sequences: 37866
Number of extensions: 492883
Number of successful extensions: 1199
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 1170
Number of HSP's gapped (non-prelim): 9
length of query: 314
length of database: 18,247,518
effective HSP length: 102
effective length of query: 212
effective length of database: 14,385,186
effective search space: 3049659432
effective search space used: 3049659432
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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