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Search of human proteins with 134304833
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|134304833 killer cell immunoglobulin-like receptor, two
domains, long cytoplasmic tail, 2 precursor [Homo sapiens]
(348 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|134304833 killer cell immunoglobulin-like receptor, two domai... 724 0.0
gi|110611923 killer cell immunoglobulin-like receptor, two domai... 684 0.0
gi|71143139 killer cell immunoglobulin-like receptor, two domain... 679 0.0
gi|6912472 killer cell immunoglobulin-like receptor, two domains... 602 e-172
gi|134268644 killer cell immunoglobulin-like receptor, three dom... 575 e-164
gi|7657277 killer cell immunoglobulin-like receptor, two domains... 568 e-162
gi|116517309 killer cell immunoglobulin-like receptor, two domai... 555 e-158
gi|6912474 killer cell immunoglobulin-like receptor, two domains... 554 e-158
gi|134268642 killer cell immunoglobulin-like receptor, three dom... 552 e-157
gi|134304835 killer cell immunoglobulin-like receptor, two domai... 548 e-156
gi|46488946 killer cell immunoglobulin-like receptor, three doma... 461 e-130
gi|11968154 killer cell immunoglobulin-like receptor, two domain... 450 e-126
gi|66267727 killer cell immunoglobulin-like receptor, two domain... 439 e-123
gi|134133244 killer cell immunoglobulin-like receptor, three dom... 426 e-119
gi|124107606 killer cell immunoglobulin-like receptor, two domai... 419 e-117
gi|62632748 killer-cell Ig-like receptor [Homo sapiens] 361 e-100
gi|124107610 killer cell immunoglobulin-like receptor, two domai... 357 1e-98
gi|124107604 killer cell immunoglobulin-like receptor, two domai... 317 1e-86
gi|71143143 killer cell immunoglobulin-like receptor, two domain... 308 6e-84
gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B... 199 3e-51
gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B... 196 2e-50
gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B... 194 1e-49
gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B... 194 1e-49
gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B... 193 2e-49
gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B... 192 3e-49
gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B... 190 2e-48
gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B... 189 2e-48
gi|125987593 leukocyte immunoglobulin-like receptor, subfamily B... 183 2e-46
gi|125987591 leukocyte immunoglobulin-like receptor, subfamily B... 183 2e-46
gi|5803070 leukocyte immunoglobulin-like receptor, subfamily B, ... 182 5e-46
>gi|134304833 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 2 precursor [Homo sapiens]
Length = 348
Score = 724 bits (1869), Expect = 0.0
Identities = 348/348 (100%), Positives = 348/348 (100%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL
Sbjct: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI
Sbjct: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
Query: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT 180
VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT
Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT 180
Query: 181 FQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
FQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGN
Sbjct: 181 FQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
Query: 241 PRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEV 300
PRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEV
Sbjct: 241 PRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEV 300
Query: 301 TYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP 348
TYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP
Sbjct: 301 TYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP 348
>gi|110611923 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 1 [Homo sapiens]
Length = 348
Score = 684 bits (1764), Expect = 0.0
Identities = 331/348 (95%), Positives = 334/348 (95%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
MSL+VVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDV FEHFLL
Sbjct: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
HREG F DTL LIGEHHDGVSKANFSI M QDLAGTYRCYGSVTHSPYQ+SAPSDPLDI
Sbjct: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120
Query: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT 180
VI GLYEKPSLSAQ GPTVLAGE+VTLSCSSRSSYDMYHLSREGEAHE R AGPKVNGT
Sbjct: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGT 180
Query: 181 FQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
FQADFPLGPATHGGTYRCFGSF DSPYEWS SSDPLLVSVTGNPSNSWPSPTEPSSKTGN
Sbjct: 181 FQADFPLGPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
Query: 241 PRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEV 300
PRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEV
Sbjct: 241 PRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEV 300
Query: 301 TYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP 348
TYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP
Sbjct: 301 TYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP 348
>gi|71143139 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 3 isoform 2 [Homo sapiens]
Length = 341
Score = 679 bits (1752), Expect = 0.0
Identities = 327/340 (96%), Positives = 330/340 (97%), Gaps = 1/340 (0%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
MSLMVVSM CVGFFLLQGAWPHEGVHRKPSLLAHPG LVKSEETVILQCWSDVRF+HFLL
Sbjct: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60
Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI
Sbjct: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
Query: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT 180
VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHE RFSAGPKVNGT
Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGT 180
Query: 181 FQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
FQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSS+TGN
Sbjct: 181 FQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSETGN 240
Query: 241 PRHLHILIGTSVVIILFI-LLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQE 299
PRHLH+LIGTSVVIILFI LLFFLLHRWC NKKNA VMDQE AGNRT N EDSDEQDPQE
Sbjct: 241 PRHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQE 300
Query: 300 VTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAE 339
VTY QLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAE
Sbjct: 301 VTYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAE 340
>gi|6912472 killer cell immunoglobulin-like receptor, two domains,
short cytoplasmic tail, 2 precursor [Homo sapiens]
Length = 304
Score = 602 bits (1553), Expect = e-172
Identities = 292/303 (96%), Positives = 295/303 (97%), Gaps = 1/303 (0%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPG LVKSEETVILQCWSDVRFEHFLL
Sbjct: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFEHFLL 60
Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
HREGK+KDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI
Sbjct: 61 HREGKYKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
Query: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT 180
VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHE RFSAGPKVNGT
Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGT 180
Query: 181 FQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
FQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGN
Sbjct: 181 FQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
Query: 241 PRHLHILIGTSVVIILF-ILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQE 299
PRHLH+LIGTSVV I F ILLFFLLHRWCSNKKNAAVMDQE AGNRT NSEDSDEQD QE
Sbjct: 241 PRHLHVLIGTSVVKIPFTILLFFLLHRWCSNKKNAAVMDQEPAGNRTVNSEDSDEQDHQE 300
Query: 300 VTY 302
V+Y
Sbjct: 301 VSY 303
>gi|134268644 killer cell immunoglobulin-like receptor, three
domains, long cytoplasmic tail, 1 precursor [Homo
sapiens]
Length = 444
Score = 575 bits (1482), Expect = e-164
Identities = 287/360 (79%), Positives = 304/360 (84%), Gaps = 17/360 (4%)
Query: 6 VSMACVGFFLLQGAWPHE----------------GVHRKPSLLAHPGRLVKSEETVILQC 49
V+ A G + +G+ PH G HRKPSLLAHPG LVKS E VILQC
Sbjct: 85 VTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGERVILQC 144
Query: 50 WSDVRFEHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPY 109
WSD+ FEHF LH+EG KD L+G+ HDGVSKANFSIGPMM LAGTYRCYGSVTH+PY
Sbjct: 145 WSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYGSVTHTPY 204
Query: 110 QLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHEC 169
QLSAPSDPLDIV+TG YEKPSLSAQPGP V AGESVTLSCSSRSSYDMYHLSREG AHE
Sbjct: 205 QLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHER 264
Query: 170 RFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWP 229
R A KVN TFQADFPLGPATHGGTYRCFGSFR SPYEWS+ SDPLLVSVTGNPS+SWP
Sbjct: 265 RLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSWP 324
Query: 230 SPTEPSSKTGNPRHLHILIGTSVVIILFI-LLFFLLHRWCSNKKNAAVMDQESAGNRTAN 288
SPTEPSSK+GNPRHLHILIGTSVVIILFI LLFFLLH WCSNKKNAAVMDQE AGNRTAN
Sbjct: 325 SPTEPSSKSGNPRHLHILIGTSVVIILFILLLFFLLHLWCSNKKNAAVMDQEPAGNRTAN 384
Query: 289 SEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP 348
SEDSDEQDP+EVTY QL+HCVFTQRKITRPSQRPKTPPTD I+YTELPNA+ RSKVVSCP
Sbjct: 385 SEDSDEQDPEEVTYAQLDHCVFTQRKITRPSQRPKTPPTDTILYTELPNAKPRSKVVSCP 444
Score = 164 bits (414), Expect = 1e-40
Identities = 97/224 (43%), Positives = 131/224 (58%), Gaps = 7/224 (3%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
MSLMVVSMACVG FL+Q A PH G KP L A P +V V L+C RF +F+L
Sbjct: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
++E D +H I H + + +F++ P+ AG Y C GS HSP SAPS+P+ I
Sbjct: 61 YKE----DRIH-IPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVI 115
Query: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT 180
++TG + KPSL A PGP V +GE V L C S ++ + L +EG + + G +G
Sbjct: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGV 175
Query: 181 FQADFPLGP--ATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTG 222
+A+F +GP GTYRC+GS +PY+ S SDPL + VTG
Sbjct: 176 SKANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTG 219
>gi|7657277 killer cell immunoglobulin-like receptor, two domains,
short cytoplasmic tail, 1 precursor [Homo sapiens]
Length = 304
Score = 568 bits (1463), Expect = e-162
Identities = 277/303 (91%), Positives = 283/303 (93%), Gaps = 1/303 (0%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
MSL VVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDV FEHFLL
Sbjct: 1 MSLTVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
HREG F DTL LIGEHHDGVSKANFSI M QDLAGTYRCYGSVTHSPYQLSAPSDPLDI
Sbjct: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMKQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
Query: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT 180
VI GLYEKPSLSAQPGPTVLAGE+VTLSCSSRSSYDMYHLSREGEAHE R AG KVNGT
Sbjct: 121 VIIGLYEKPSLSAQPGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGTKVNGT 180
Query: 181 FQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
FQA+FPLGPATHGGTYRCFGSFRDSPYEWS SSDPLLVSVTGNPSNSWPSPTEPSS+TGN
Sbjct: 181 FQANFPLGPATHGGTYRCFGSFRDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSETGN 240
Query: 241 PRHLHILIGTSVVIILF-ILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQE 299
PRHLH+LIGTSVV I F ILLFFLLHRWCS+KKNAAVMDQE AGNRT NSEDSDEQD QE
Sbjct: 241 PRHLHVLIGTSVVKIPFTILLFFLLHRWCSDKKNAAVMDQEPAGNRTVNSEDSDEQDHQE 300
Query: 300 VTY 302
V+Y
Sbjct: 301 VSY 303
>gi|116517309 killer cell immunoglobulin-like receptor, two domains,
short cytoplasmic tail, 4 [Homo sapiens]
Length = 304
Score = 555 bits (1430), Expect = e-158
Identities = 270/303 (89%), Positives = 279/303 (92%), Gaps = 1/303 (0%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
MSLMV+ MACVGFFLLQGAWP EGVHRKPS LA PG LVKSEETVILQCWSDV FEHFLL
Sbjct: 1 MSLMVIIMACVGFFLLQGAWPQEGVHRKPSFLALPGHLVKSEETVILQCWSDVMFEHFLL 60
Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
HREGKF +TLHLIGEHHDGVSKANFSIGPMM LAGTYRCYGSV HSPYQLSAPSDPLD+
Sbjct: 61 HREGKFNNTLHLIGEHHDGVSKANFSIGPMMPVLAGTYRCYGSVPHSPYQLSAPSDPLDM 120
Query: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT 180
VI GLYEKPSLSAQPGPTV AGE+VTLSCSSRSSYDMYHLSREGEAHE R A +NGT
Sbjct: 121 VIIGLYEKPSLSAQPGPTVQAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAVRSINGT 180
Query: 181 FQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
FQADFPLGPATHGGTYRCFGSFRD+PYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGN
Sbjct: 181 FQADFPLGPATHGGTYRCFGSFRDAPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
Query: 241 PRHLHILIGTSVVIILF-ILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQE 299
PRHLH+LIGTSVV I F ILLFFLLHRWCS+KKNAAVMDQE AGNRT NSEDSDEQD QE
Sbjct: 241 PRHLHVLIGTSVVKIPFTILLFFLLHRWCSDKKNAAVMDQEPAGNRTVNSEDSDEQDHQE 300
Query: 300 VTY 302
V+Y
Sbjct: 301 VSY 303
>gi|6912474 killer cell immunoglobulin-like receptor, two domains,
short cytoplasmic tail, 3 [Homo sapiens]
Length = 304
Score = 554 bits (1427), Expect = e-158
Identities = 271/303 (89%), Positives = 277/303 (91%), Gaps = 1/303 (0%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
MSLMV+SMACVGFF LQGAWPHEG RKPSLLAHPGRLVKSEETVILQCWSDV FEHFLL
Sbjct: 1 MSLMVISMACVGFFWLQGAWPHEGFRRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
HREG F DTL LIGEH DGVSKANFSIG M QDLAGTYRCYGSV HSPYQ SAPSDPLDI
Sbjct: 61 HREGTFNDTLRLIGEHIDGVSKANFSIGRMRQDLAGTYRCYGSVPHSPYQFSAPSDPLDI 120
Query: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT 180
VITGLYEKPSLSAQPGPTVLAGESVTLSCSS SSYDMYHLS EGEAHE RFSAGPKVNGT
Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSWSSYDMYHLSTEGEAHERRFSAGPKVNGT 180
Query: 181 FQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
FQADFPLGPAT GGTYRCFGSF DSPYEWS SSDPLLVSVTGNPSNSWPSPTEPSSKTGN
Sbjct: 181 FQADFPLGPATQGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
Query: 241 PRHLHILIGTSVVIILF-ILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQE 299
PRHLH+LIGTSVV + F ILLFFLLHRWCS+KKNA+VMDQ AGNRT N EDSDEQD QE
Sbjct: 241 PRHLHVLIGTSVVKLPFTILLFFLLHRWCSDKKNASVMDQGPAGNRTVNREDSDEQDHQE 300
Query: 300 VTY 302
V+Y
Sbjct: 301 VSY 303
>gi|134268642 killer cell immunoglobulin-like receptor, three
domains, long cytoplasmic tail, 2 precursor [Homo
sapiens]
Length = 455
Score = 552 bits (1423), Expect = e-157
Identities = 279/360 (77%), Positives = 298/360 (82%), Gaps = 17/360 (4%)
Query: 6 VSMACVGFFLLQGAWPHE----------------GVHRKPSLLAHPGRLVKSEETVILQC 49
V+ A G + +G+ PH G HRKPSLLAHPG L+KS ETVILQC
Sbjct: 85 VTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGNHRKPSLLAHPGPLLKSGETVILQC 144
Query: 50 WSDVRFEHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPY 109
WSDV FEHF LHREG +D L+G+ HDGVSKANFSIGP+M LAGTYRCYGSV HSPY
Sbjct: 145 WSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANFSIGPLMPVLAGTYRCYGSVPHSPY 204
Query: 110 QLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHEC 169
QLSAPSDPLDIVITGLYEKPSLSAQPGPTV AGE+VTLSCSS SSYD+YHLSREGEAHE
Sbjct: 205 QLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGENVTLSCSSWSSYDIYHLSREGEAHER 264
Query: 170 RFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWP 229
R A PKVN TFQADFPLGPATHGGTYRCFGSFR P WSNSSDPLLVSVTGNPS+SWP
Sbjct: 265 RLRAVPKVNRTFQADFPLGPATHGGTYRCFGSFRALPCVWSNSSDPLLVSVTGNPSSSWP 324
Query: 230 SPTEPSSKTGNPRHLHILIGTSVVIILFI-LLFFLLHRWCSNKKNAAVMDQESAGNRTAN 288
SPTEPSSK+G RHLH+LIGTSVVI LFI LLFFLL+RWCSNKKNAAVMDQE AG+RT N
Sbjct: 325 SPTEPSSKSGICRHLHVLIGTSVVIFLFILLLFFLLYRWCSNKKNAAVMDQEPAGDRTVN 384
Query: 289 SEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP 348
+DSDEQDPQEVTY QL+HCVF QRKI+RPSQRPKTP TD VYTELPNAE RSKVVSCP
Sbjct: 385 RQDSDEQDPQEVTYAQLDHCVFIQRKISRPSQRPKTPLTDTSVYTELPNAEPRSKVVSCP 444
Score = 172 bits (436), Expect = 4e-43
Identities = 106/238 (44%), Positives = 139/238 (58%), Gaps = 11/238 (4%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
MSL VVSMACVGFFLLQGAWP G KP L A P +V V LQC F +F+L
Sbjct: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60
Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
++E D H + H + + +F +GP+ AGTYRC GS HS SAPS+PL I
Sbjct: 61 YKE----DRSH-VPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVI 115
Query: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT 180
++TG + KPSL A PGP + +GE+V L C S ++ + L REG + + G +G
Sbjct: 116 MVTGNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGV 175
Query: 181 FQADFPLGP--ATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTG---NPS-NSWPSPT 232
+A+F +GP GTYRC+GS SPY+ S SDPL + +TG PS ++ P PT
Sbjct: 176 SKANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPT 233
>gi|134304835 killer cell immunoglobulin-like receptor, two domains,
short cytoplasmic tail, 5 [Homo sapiens]
Length = 304
Score = 548 bits (1413), Expect = e-156
Identities = 269/303 (88%), Positives = 275/303 (90%), Gaps = 1/303 (0%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
MSLMV+SMACV FFLLQGAWPHEG RKPSLLAHPG LVKSEETVILQCWSDV FEHFLL
Sbjct: 1 MSLMVISMACVAFFLLQGAWPHEGFRRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLL 60
Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
HREG F TL LIGEH DGVSK NFSIG M QDLAGTYRCYGSVTHSPYQLSAPSDPLDI
Sbjct: 61 HREGTFNHTLRLIGEHIDGVSKGNFSIGRMTQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
Query: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT 180
VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHE R AGPKVN T
Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNRT 180
Query: 181 FQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
FQADFPL PATHGGTYRCFGSFRDSPYEWS SSDPLLVSVTGN SNSWPSPTEPSS+TGN
Sbjct: 181 FQADFPLDPATHGGTYRCFGSFRDSPYEWSKSSDPLLVSVTGNSSNSWPSPTEPSSETGN 240
Query: 241 PRHLHILIGTSVVIILF-ILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQE 299
PRHLH+LIGTSVV + F ILLFFLLHRWCSNKKNA+VMDQ AGNRT N EDSDEQD QE
Sbjct: 241 PRHLHVLIGTSVVKLPFTILLFFLLHRWCSNKKNASVMDQGPAGNRTVNREDSDEQDHQE 300
Query: 300 VTY 302
V+Y
Sbjct: 301 VSY 303
>gi|46488946 killer cell immunoglobulin-like receptor, three
domains, long cytoplasmic tail, 3 [Homo sapiens]
Length = 410
Score = 461 bits (1186), Expect = e-130
Identities = 231/309 (74%), Positives = 250/309 (80%), Gaps = 18/309 (5%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEHHDGVSKA 83
GVHRKPSLLAHPG LVKS ETVILQCWSDVRFE FLLHREG +D L L+G+ HD S+
Sbjct: 119 GVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQV 178
Query: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGE 143
N+S+GPM LAGTYRC+GSVTH PY+LSAPSDPLDIV+ GLY KPSLSAQPGPTV AGE
Sbjct: 179 NYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGE 238
Query: 144 SVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFR 203
+VTLSCSSRS +D+YHLSRE EA E R +A +VNGTFQA+FPLGP THGG YRCFGSFR
Sbjct: 239 NVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFR 298
Query: 204 DSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGNPRHLHILIGTSVVIILF-ILLFF 262
P+ WS+ SDPL VSV TGN RHLH+LIGTSVVII F ILLFF
Sbjct: 299 ALPHAWSDPSDPLPVSV-----------------TGNSRHLHVLIGTSVVIIPFAILLFF 341
Query: 263 LLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRP 322
LLHRWC+NKKNA VMDQE AGNRT N EDSDEQDPQEVTY QLNHCVFTQRKITRPSQRP
Sbjct: 342 LLHRWCANKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRP 401
Query: 323 KTPPTDIIV 331
KTPPTD V
Sbjct: 402 KTPPTDTSV 410
Score = 179 bits (455), Expect = 3e-45
Identities = 106/238 (44%), Positives = 139/238 (58%), Gaps = 11/238 (4%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
MSLMVVSMACVGFFLL+G WPH G KP L A PG +V + V LQC S + F F L
Sbjct: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60
Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
+E + E ++ + + +F +GP+ AGTYRC S HSP SAPS+P+ I
Sbjct: 61 SKEDGMP-----VPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVI 115
Query: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT 180
++TG++ KPSL A PGP V +GE+V L C S ++ + L REG + G +
Sbjct: 116 MVTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAG 175
Query: 181 FQADFPLGPATH--GGTYRCFGSFRDSPYEWSNSSDPL---LVSVTGNPS-NSWPSPT 232
Q ++ +GP T GTYRCFGS PYE S SDPL +V + G PS ++ P PT
Sbjct: 176 SQVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPT 233
>gi|11968154 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 5A [Homo sapiens]
Length = 375
Score = 450 bits (1157), Expect = e-126
Identities = 235/343 (68%), Positives = 261/343 (76%), Gaps = 6/343 (1%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
MSLMV+SMACVGFFLLQGAW HEG KP L A P +V V L C S + F F L
Sbjct: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60
Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
++E + E ++ + + +GP+ AGTYRC GS SP + SAPS+PL I
Sbjct: 61 YKEDGVP-----VPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVI 115
Query: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT 180
V+TGL+ KPSLSAQPGPTV GE+VTLSCSSRSS+DMYHLSREG AHE R A P VNGT
Sbjct: 116 VVTGLFGKPSLSAQPGPTVRTGENVTLSCSSRSSFDMYHLSREGRAHEPRLPAVPSVNGT 175
Query: 181 FQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
FQADFPLGPATHGGTY CFGS DSPYEWS+ SDPLLVSVTGN S+S SPTEPSSKTG
Sbjct: 176 FQADFPLGPATHGGTYTCFGSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGI 235
Query: 241 PRHLHILIGTSVVIILFILL-FFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQE 299
RHLHILIGTSV IILFI+L FFLLH CSNKKNAAVMDQE AG+RT N EDSD+QDPQE
Sbjct: 236 RRHLHILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQEPAGDRTVNREDSDDQDPQE 295
Query: 300 VTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRS 342
VTY QL+HCVFTQ KIT PSQRPKTPPTD +Y ELPNA+ RS
Sbjct: 296 VTYAQLDHCVFTQTKITSPSQRPKTPPTDTTMYMELPNAKPRS 338
>gi|66267727 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 5B precursor [Homo sapiens]
Length = 375
Score = 439 bits (1129), Expect = e-123
Identities = 230/343 (67%), Positives = 257/343 (74%), Gaps = 6/343 (1%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
MSLMV+SMACVGFFLLQGAW HEG KP L A P +V V L C S + F F L
Sbjct: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60
Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
++E + E ++ + + +GP+ AGTYRC GS SP + SAPS+PL I
Sbjct: 61 YKEDGVP-----VPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVI 115
Query: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT 180
V+TGL+ KPSLSAQPGPTV GE+V LSCSSRSS+DMYHLSREG AHE R A P V+GT
Sbjct: 116 VVTGLFGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGT 175
Query: 181 FQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
FQADFPLGPATHGGTY CF S DSPYEWS+ SDPLLVSVTGN S+S SPTEPSSKTG
Sbjct: 176 FQADFPLGPATHGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGI 235
Query: 241 PRHLHILIGTSVVIILFILL-FFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQE 299
RHLHILIGTSV IILFI+L FFLLH CSNKKNAAVMDQ AG+RT N EDSD+QDPQE
Sbjct: 236 RRHLHILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQGPAGDRTVNREDSDDQDPQE 295
Query: 300 VTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRS 342
VTY QL+HCVFTQ KIT PSQRPK PPTD +Y ELPNA+ RS
Sbjct: 296 VTYAQLDHCVFTQTKITSPSQRPKAPPTDTTMYMELPNAKPRS 338
>gi|134133244 killer cell immunoglobulin-like receptor, three
domains, short cytoplasmic tail, 1 [Homo sapiens]
Length = 382
Score = 426 bits (1096), Expect = e-119
Identities = 216/284 (76%), Positives = 230/284 (80%), Gaps = 17/284 (5%)
Query: 6 VSMACVGFFLLQGAWPHE----------------GVHRKPSLLAHPGRLVKSEETVILQC 49
V+ A G + +G+ PH G HRKPSLLAHPG LVKS E VILQC
Sbjct: 85 VTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSGERVILQC 144
Query: 50 WSDVRFEHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPY 109
WSD+ FEHF LH+E KD L+G+ HDGVSKANFSIG MM+ LAGTYRCYGSVTH+PY
Sbjct: 145 WSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYGSVTHTPY 204
Query: 110 QLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHEC 169
QLSAPSDPLDIV+TGLYEKPSLSAQPGP V AGESVTLSCSSRSSYDMYHLSREG AHE
Sbjct: 205 QLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHER 264
Query: 170 RFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWP 229
R A KVN TFQADFPLGPATHGGTYRCFGSFR SPYEWS+ SDPLLVSVTGNPS+SWP
Sbjct: 265 RLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSWP 324
Query: 230 SPTEPSSKTGNPRHLHILIGTSVVIILF-ILLFFLLHRWCSNKK 272
SPTEPSSK+GN RHLHILIGTSVV I F ILLFFLLHRWCSNKK
Sbjct: 325 SPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFFLLHRWCSNKK 368
Score = 155 bits (393), Expect = 4e-38
Identities = 93/224 (41%), Positives = 127/224 (56%), Gaps = 7/224 (3%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
M LMVVSMACVG FL+Q A PH G KP L A P +V V L+C RF +F+L
Sbjct: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
++E D +H + H + + F++ P+ AG Y C GS HSP SAPS+P+ I
Sbjct: 61 YKE----DRIH-VPIFHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVI 115
Query: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT 180
++TG + KPSL A PGP V +GE V L C S ++ + L +E + + G +G
Sbjct: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGV 175
Query: 181 FQADFPLGPATH--GGTYRCFGSFRDSPYEWSNSSDPLLVSVTG 222
+A+F +G GTYRC+GS +PY+ S SDPL + VTG
Sbjct: 176 SKANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTG 219
>gi|124107606 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 4 isoform a [Homo sapiens]
Length = 377
Score = 419 bits (1078), Expect = e-117
Identities = 219/343 (63%), Positives = 252/343 (73%), Gaps = 6/343 (1%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
MS V+ +AC+GFFL Q W H G KP A P +V V L+C F F L
Sbjct: 3 MSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTL 62
Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
++ KD + + E ++ + +F I P+ AGTYRC G HSP + SAPS+PL I
Sbjct: 63 YK----KDGVP-VPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVI 117
Query: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT 180
++TGLYEKPSL+A+PGPTV AGE+VTLSCSS+SS+D+YHLSREGEAHE R A P +NGT
Sbjct: 118 MVTGLYEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGT 177
Query: 181 FQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
FQADFPLGPATHG TYRCFGSF SPYEWS+ SDPL VSVTGNPS+SWPSPTEPS KTG
Sbjct: 178 FQADFPLGPATHGETYRCFGSFHGSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKTGI 237
Query: 241 PRHLHILIGTSVVIILF-ILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQE 299
RHLH +I SV IILF IL FFLLHRWCS KKNAAVM+QE AG+RT N EDSDEQDPQE
Sbjct: 238 ARHLHAVIRYSVAIILFTILPFFLLHRWCSKKKNAAVMNQEPAGHRTVNREDSDEQDPQE 297
Query: 300 VTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRS 342
VTY QL+HC+FTQRKIT PSQR K P TD V ELPNAE R+
Sbjct: 298 VTYAQLDHCIFTQRKITGPSQRSKRPSTDTSVCIELPNAEPRA 340
>gi|62632748 killer-cell Ig-like receptor [Homo sapiens]
Length = 328
Score = 361 bits (926), Expect = e-100
Identities = 183/232 (78%), Positives = 190/232 (81%), Gaps = 16/232 (6%)
Query: 6 VSMACVGFFLLQGAWPH----------------EGVHRKPSLLAHPGRLVKSEETVILQC 49
V+ A G + +G+ PH GVHRKPSLLAHPG LVKSEETVILQC
Sbjct: 85 VTPAHAGTYRCRGSHPHFLTGWSAPSNPLVIMVTGVHRKPSLLAHPGPLVKSEETVILQC 144
Query: 50 WSDVRFEHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPY 109
WSDV FEHFLLHREGKF DTL L GE HDGVSKANFSIG M QDLAGTYRCYGSV HSPY
Sbjct: 145 WSDVMFEHFLLHREGKFNDTLRLTGELHDGVSKANFSIGRMTQDLAGTYRCYGSVPHSPY 204
Query: 110 QLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHEC 169
QLSAPSDPLDIVITGL KPSLSAQP P V AGESVTLSCSSRSSYD+YHLSREGEAHE
Sbjct: 205 QLSAPSDPLDIVITGLCGKPSLSAQPRPMVKAGESVTLSCSSRSSYDIYHLSREGEAHEL 264
Query: 170 RFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVT 221
RF A PKVNGTFQA+FPLGPATHGGTYRCFGSFRDSPYEWS+ SDPLLVSVT
Sbjct: 265 RFPAVPKVNGTFQANFPLGPATHGGTYRCFGSFRDSPYEWSDLSDPLLVSVT 316
Score = 174 bits (442), Expect = 8e-44
Identities = 102/224 (45%), Positives = 132/224 (58%), Gaps = 7/224 (3%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
MSLMV+SMACVGFFLLQGAW HEG KP L A P +V E V LQC S + F F L
Sbjct: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPFLSAWPSPVVSEGEHVALQCRSRLGFNEFSL 60
Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
+E + E ++ V + IGP+ AGTYRC GS H SAPS+PL I
Sbjct: 61 SKEDGMP-----VPELYNRVFRNTVFIGPVTPAHAGTYRCRGSHPHFLTGWSAPSNPLVI 115
Query: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT 180
++TG++ KPSL A PGP V + E+V L C S ++ + L REG+ ++ G +G
Sbjct: 116 MVTGVHRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLLHREGKFNDTLRLTGELHDGV 175
Query: 181 FQADFPLGPATH--GGTYRCFGSFRDSPYEWSNSSDPLLVSVTG 222
+A+F +G T GTYRC+GS SPY+ S SDPL + +TG
Sbjct: 176 SKANFSIGRMTQDLAGTYRCYGSVPHSPYQLSAPSDPLDIVITG 219
>gi|124107610 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 4 isoform c [Homo sapiens]
Length = 342
Score = 357 bits (915), Expect = 1e-98
Identities = 193/342 (56%), Positives = 226/342 (66%), Gaps = 39/342 (11%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
MS V+ +AC+GFFL Q W H G KP A P +V V L+C F F L
Sbjct: 3 MSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTL 62
Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
++ KD + + E ++ + +F I P+ AGTYRC G HSP + SAPS+PL I
Sbjct: 63 YK----KDGVP-VPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVI 117
Query: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT 180
++TGLYEKPSL+A+PGPTV AGE+VTLSCSS+SS+D+YHLSREGEAHE R A P +NGT
Sbjct: 118 MVTGLYEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGT 177
Query: 181 FQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
FQADFPLGPATHG TYRCFGSF SPYEWS+ SDPL VSVTGNPS+SWPSPTEPS KT
Sbjct: 178 FQADFPLGPATHGETYRCFGSFHGSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKT-- 235
Query: 241 PRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEV 300
+AAVM+QE AG+RT N EDSDEQDPQEV
Sbjct: 236 --------------------------------DAAVMNQEPAGHRTVNREDSDEQDPQEV 263
Query: 301 TYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRS 342
TY QL+HC+FTQRKIT PSQR K P TD V ELPNAE R+
Sbjct: 264 TYAQLDHCIFTQRKITGPSQRSKRPSTDTSVCIELPNAEPRA 305
>gi|124107604 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 4 isoform b [Homo sapiens]
Length = 273
Score = 317 bits (811), Expect = 1e-86
Identities = 167/273 (61%), Positives = 195/273 (71%), Gaps = 6/273 (2%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
MS V+ +AC+GFFL Q W H G KP A P +V V L+C F F L
Sbjct: 3 MSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTL 62
Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
++ KD + + E ++ + +F I P+ AGTYRC G HSP + SAPS+PL I
Sbjct: 63 YK----KDGVP-VPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVI 117
Query: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT 180
++TGLYEKPSL+A+PGPTV AGE+VTLSCSS+SS+D+YHLSREGEAHE R A P +NGT
Sbjct: 118 MVTGLYEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGT 177
Query: 181 FQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGN 240
FQADFPLGPATHG TYRCFGSF SPYEWS+ SDPL VSVTGNPS+SWPSPTEPS KTG
Sbjct: 178 FQADFPLGPATHGETYRCFGSFHGSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKTGI 237
Query: 241 PRHLHILIGTSVVIILF-ILLFFLLHRWCSNKK 272
RHLH +I SV IILF IL FFLLHRWCS KK
Sbjct: 238 ARHLHAVIRYSVAIILFTILPFFLLHRWCSKKK 270
>gi|71143143 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 3 isoform 1 [Homo sapiens]
Length = 243
Score = 308 bits (788), Expect = 6e-84
Identities = 155/219 (70%), Positives = 171/219 (78%), Gaps = 3/219 (1%)
Query: 124 GLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQA 183
G++ KPSL A PGP V + E+V L C S + + L REG+ + G +G +A
Sbjct: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83
Query: 184 DFPLGPATH--GGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGNP 241
+F +GP GTYRC+GS SPY+ S SDPLLVSVTGNPSNSWPSPTEPSS+TGNP
Sbjct: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNP 143
Query: 242 RHLHILIGTSVVIILFILL-FFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEV 300
RHLH+LIGTSVVIILFILL FFLLHRWC NKKNA VMDQE AGNRT N EDSDEQDPQEV
Sbjct: 144 RHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEV 203
Query: 301 TYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAE 339
TY QLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAE
Sbjct: 204 TYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAE 242
Score = 252 bits (643), Expect = 4e-67
Identities = 123/144 (85%), Positives = 130/144 (90%), Gaps = 4/144 (2%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
MSLMVVSM CVGFFLLQGAWPHEGVHRKPSLLAHPG LVKSEETVILQCWSDVRF+HFLL
Sbjct: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60
Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPL +
Sbjct: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120
Query: 121 VITGLYEKPSLSAQPGPTVLAGES 144
+TG PS ++ P PT + E+
Sbjct: 121 SVTG---NPS-NSWPSPTEPSSET 140
>gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B,
member 3 isoform 2 [Homo sapiens]
Length = 631
Score = 199 bits (506), Expect = 3e-51
Identities = 130/353 (36%), Positives = 189/353 (53%), Gaps = 57/353 (16%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEHHD-GVSK 82
GV RKPSLL G ++ +++ LQC SDV + F+L++EG+ +D L G+ G+S+
Sbjct: 220 GVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGE-RDFLQRPGQQPQAGLSQ 278
Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITG-LYEKPSLSAQPGPTVLA 141
ANF++GP+ G YRCYG+ S + SAPSDPL+I++ G +Y+ SLSAQPGPTV +
Sbjct: 279 ANFTLGPVSPSNGGQYRCYGAHNLSS-EWSAPSDPLNILMAGQIYDTVSLSAQPGPTVAS 337
Query: 142 GESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPAT--HGGTYRCF 199
GE+VTL C S +D + L++EG AH +QA+FP+ P T H GTYRC+
Sbjct: 338 GENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCY 397
Query: 200 GSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGNPRHLHILIGTSV--VIILF 257
GS+ +P+ S+ S+PL + V+G+ S PT P S G R+L +LIG SV V++LF
Sbjct: 398 GSYSSNPHLLSHPSEPLELVVSGHSGGSSLPPTGPPSTPGLGRYLEVLIGVSVAFVLLLF 457
Query: 258 ILLFFLL-------HRWCSNKKN----------------------------------AAV 276
+LLF LL HR +K AAV
Sbjct: 458 LLLFLLLRRQRHSKHRTSDQRKTDFQRPAGAAETEPKDRGLLRRSSPAADVQEENLYAAV 517
Query: 277 MDQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDI 329
D +S +S+ ++DPQ VTY + H + P + +PP+ +
Sbjct: 518 KDTQSEDRVELDSQSPHDEDPQAVTYAPVKH--------SSPRREMASPPSSL 562
Score = 122 bits (305), Expect = 6e-28
Identities = 76/225 (33%), Positives = 117/225 (52%), Gaps = 8/225 (3%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
M+ + ++ C+G L G KP+L A PG ++ V + C + + L
Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRL 60
Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
H+EG + + +KA FSI M + AG YRC+ +S S PSDPL++
Sbjct: 61 HKEGSPEPLDR--NNPLEPKNKARFSIPSMTEHHAGRYRCH---YYSSAGWSEPSDPLEM 115
Query: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT 180
V+TG Y KP+LSA P P V +G ++TL C S+ Y + L +EGE R +++
Sbjct: 116 VMTGAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSR 175
Query: 181 -FQADFPLGPAT--HGGTYRCFGSFRDSPYEWSNSSDPLLVSVTG 222
FQA FP+GP T H + C+ + ++P+ WS+ SDPL + +G
Sbjct: 176 GFQALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSG 220
Score = 122 bits (305), Expect = 6e-28
Identities = 77/222 (34%), Positives = 116/222 (52%), Gaps = 9/222 (4%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEH-HDGVSK 82
G + KP+L A P +V S + L+C S + HF+L +EG+ + L + H +
Sbjct: 119 GAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQ 178
Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAG 142
A F +GP+ + CY T++P+ S PSDPL+I+ +G+ KPSL GP + G
Sbjct: 179 ALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPG 238
Query: 143 ESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPA--THGGTYRCFG 200
+S+TL C S Y+ + L +EGE + G QA+F LGP ++GG YRC+G
Sbjct: 239 QSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYG 298
Query: 201 SFRDSPYEWSNSSDPLLVSVTGN-----PSNSWPSPTEPSSK 237
+ S EWS SDPL + + G ++ P PT S +
Sbjct: 299 AHNLSS-EWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGE 339
Score = 75.9 bits (185), Expect = 5e-14
Identities = 85/337 (25%), Positives = 126/337 (37%), Gaps = 65/337 (19%)
Query: 30 SLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGP 89
SL A PG V S E V L C S +F+ FLL +EG L L + +A F + P
Sbjct: 326 SLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSP 385
Query: 90 MMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPT---------VL 140
+ AGTYRCYGS + +P+ LS PS+PL++V++G SL P+ VL
Sbjct: 386 VTSAHAGTYRCYGSYSSNPHLLSHPSEPLELVVSGHSGGSSLPPTGPPSTPGLGRYLEVL 445
Query: 141 AGESVT--------LSCSSRSSYDMYHLSREGEAHECRFSAG-----PKVNGTFQADFPL 187
G SV L R H + + + + AG PK G + P
Sbjct: 446 IGVSVAFVLLLFLLLFLLLRRQRHSKHRTSDQRKTDFQRPAGAAETEPKDRGLLRRSSPA 505
Query: 188 GPATHGGTYRCFGSFRDSPY-----EWSNSSDPLLVSVT----GNPSNSWPSPTEPSSKT 238
Y + + + DP V+ +P SP PSS +
Sbjct: 506 ADVQEENLYAAVKDTQSEDRVELDSQSPHDEDPQAVTYAPVKHSSPRREMASP--PSSLS 563
Query: 239 GNPRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQ 298
G FL D++ +R ++E + + Q
Sbjct: 564 GE---------------------FL-----------DTKDRQVEEDRQMDTEAAASEASQ 591
Query: 299 EVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTEL 335
+VTY QL+ ++ P + PP + +Y L
Sbjct: 592 DVTYAQLHSLTLRRKATEPPPSQEGEPPAEPSIYATL 628
>gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B,
member 3 isoform 1 [Homo sapiens]
Length = 632
Score = 196 bits (499), Expect = 2e-50
Identities = 131/354 (37%), Positives = 190/354 (53%), Gaps = 58/354 (16%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEHHD-GVSK 82
GV RKPSLL G ++ +++ LQC SDV + F+L++EG+ +D L G+ G+S+
Sbjct: 220 GVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGE-RDFLQRPGQQPQAGLSQ 278
Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITG-LYEKPSLSAQPGPTVLA 141
ANF++GP+ G YRCYG+ S + SAPSDPL+I++ G +Y+ SLSAQPGPTV +
Sbjct: 279 ANFTLGPVSPSNGGQYRCYGAHNLSS-EWSAPSDPLNILMAGQIYDTVSLSAQPGPTVAS 337
Query: 142 GESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPAT--HGGTYRCF 199
GE+VTL C S +D + L++EG AH +QA+FP+ P T H GTYRC+
Sbjct: 338 GENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCY 397
Query: 200 GSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGNPRHLHILIGTSV--VIILF 257
GS+ +P+ S+ S+PL + V+G+ S PT P S G R+L +LIG SV V++LF
Sbjct: 398 GSYSSNPHLLSHPSEPLELVVSGHSGGSSLPPTGPPSTPGLGRYLEVLIGVSVAFVLLLF 457
Query: 258 ILLFFLL-------HRWCSNKKN----------------------------------AAV 276
+LLF LL HR +K AAV
Sbjct: 458 LLLFLLLRRQRHSKHRTSDQRKTDFQRPAGAAETEPKDRGLLRRSSPAADVQEENLYAAV 517
Query: 277 MDQESAGNRTANSEDS-DEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDI 329
D +S +S+ S ++DPQ VTY + H + P + +PP+ +
Sbjct: 518 KDTQSEDRVELDSQQSPHDEDPQAVTYAPVKH--------SSPRREMASPPSSL 563
Score = 122 bits (305), Expect = 6e-28
Identities = 76/225 (33%), Positives = 117/225 (52%), Gaps = 8/225 (3%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
M+ + ++ C+G L G KP+L A PG ++ V + C + + L
Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRL 60
Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
H+EG + + +KA FSI M + AG YRC+ +S S PSDPL++
Sbjct: 61 HKEGSPEPLDR--NNPLEPKNKARFSIPSMTEHHAGRYRCH---YYSSAGWSEPSDPLEM 115
Query: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT 180
V+TG Y KP+LSA P P V +G ++TL C S+ Y + L +EGE R +++
Sbjct: 116 VMTGAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSR 175
Query: 181 -FQADFPLGPAT--HGGTYRCFGSFRDSPYEWSNSSDPLLVSVTG 222
FQA FP+GP T H + C+ + ++P+ WS+ SDPL + +G
Sbjct: 176 GFQALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSG 220
Score = 122 bits (305), Expect = 6e-28
Identities = 77/222 (34%), Positives = 116/222 (52%), Gaps = 9/222 (4%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEH-HDGVSK 82
G + KP+L A P +V S + L+C S + HF+L +EG+ + L + H +
Sbjct: 119 GAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQ 178
Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAG 142
A F +GP+ + CY T++P+ S PSDPL+I+ +G+ KPSL GP + G
Sbjct: 179 ALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPG 238
Query: 143 ESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPA--THGGTYRCFG 200
+S+TL C S Y+ + L +EGE + G QA+F LGP ++GG YRC+G
Sbjct: 239 QSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYG 298
Query: 201 SFRDSPYEWSNSSDPLLVSVTGN-----PSNSWPSPTEPSSK 237
+ S EWS SDPL + + G ++ P PT S +
Sbjct: 299 AHNLSS-EWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGE 339
Score = 76.6 bits (187), Expect = 3e-14
Identities = 83/329 (25%), Positives = 130/329 (39%), Gaps = 48/329 (14%)
Query: 30 SLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGP 89
SL A PG V S E V L C S +F+ FLL +EG L L + +A F + P
Sbjct: 326 SLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSP 385
Query: 90 MMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPT---------VL 140
+ AGTYRCYGS + +P+ LS PS+PL++V++G SL P+ VL
Sbjct: 386 VTSAHAGTYRCYGSYSSNPHLLSHPSEPLELVVSGHSGGSSLPPTGPPSTPGLGRYLEVL 445
Query: 141 AGESVT--------LSCSSRSSYDMYHLSREGEAHECRFSAG-----PKVNGTFQADFPL 187
G SV L R H + + + + AG PK G + P
Sbjct: 446 IGVSVAFVLLLFLLLFLLLRRQRHSKHRTSDQRKTDFQRPAGAAETEPKDRGLLRRSSPA 505
Query: 188 GPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSP-TEPSSKTGNPRHLHI 246
Y + +D+ S D + + +P + P T K +PR
Sbjct: 506 ADVQEENLY---AAVKDT-----QSEDRVELDSQQSPHDEDPQAVTYAPVKHSSPRREMA 557
Query: 247 LIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEVTYTQLN 306
+S+ + + D++ +R ++E + + Q+VTY QL+
Sbjct: 558 SPPSSL-----------------SGEFLDTKDRQVEEDRQMDTEAAASEASQDVTYAQLH 600
Query: 307 HCVFTQRKITRPSQRPKTPPTDIIVYTEL 335
++ P + PP + +Y L
Sbjct: 601 SLTLRRKATEPPPSQEGEPPAEPSIYATL 629
>gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 4 [Homo sapiens]
Length = 651
Score = 194 bits (493), Expect = 1e-49
Identities = 132/364 (36%), Positives = 188/364 (51%), Gaps = 44/364 (12%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIG-EHHDGVSK 82
GV +KPSL PG +V EET+ LQC SD + F+L+++G+ +D L L G + G+S+
Sbjct: 221 GVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGE-RDFLQLAGAQPQAGLSQ 279
Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITG-LYEKPSLSAQPGPTVLA 141
ANF++GP+ + G YRCYG+ S + SAPSDPLDI+I G Y++ SLS QPGPTV +
Sbjct: 280 ANFTLGPVSRSYGGQYRCYGAHNLSS-EWSAPSDPLDILIAGQFYDRVSLSVQPGPTVAS 338
Query: 142 GESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPAT--HGGTYRCF 199
GE+VTL C S+ + L++EG A + + +QA+FP+GP T H GTYRC+
Sbjct: 339 GENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCY 398
Query: 200 GSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGNP-----------------R 242
GS PY ++ SDPL + V+G PS SPT + T P R
Sbjct: 399 GSQSSKPYLLTHPSDPLELVVSG-PSGGPSSPTTGPTSTSGPEDQPLTPTGSDPQSGLGR 457
Query: 243 HLHILIGTSVVIILFILLFFLL-----HR-----WCSNKKNAAVMDQESA--------GN 284
HL ++IG V +IL +LL LL HR W S ++ A A G
Sbjct: 458 HLGVVIGILVAVILLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGL 517
Query: 285 RTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKV 344
+ +S +D Q +E Y + H Q P + Y E+ ++ R ++
Sbjct: 518 QWRSSPAADAQ--EENLYAAVKHTQPEDGVEMDTRQSPHDEDPQAVTYAEVKHSRPRREM 575
Query: 345 VSCP 348
S P
Sbjct: 576 ASPP 579
Score = 145 bits (367), Expect = 4e-35
Identities = 83/202 (41%), Positives = 119/202 (58%), Gaps = 4/202 (1%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEHHD-GVSK 82
G + KP+L A P +V S VILQC S V F+ F L +EG+ + L + H G S+
Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179
Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAG 142
A FS+GP+ YRCY ++SPY+ S PSD L++++ G+ +KPSLS QPGP V
Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239
Query: 143 ESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPA--THGGTYRCFG 200
E++TL C S + Y+ + L ++GE + + G QA+F LGP ++GG YRC+G
Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYG 299
Query: 201 SFRDSPYEWSNSSDPLLVSVTG 222
+ S EWS SDPL + + G
Sbjct: 300 AHNLSS-EWSAPSDPLDILIAG 320
Score = 120 bits (302), Expect = 1e-27
Identities = 81/226 (35%), Positives = 117/226 (51%), Gaps = 9/226 (3%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
M+ ++ + C+G L G KP+L A PG ++ V L+C + + L
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCY-GSVTHSPYQLSAPSDPLD 119
+RE K L + + V K F I + + AG YRCY GS T S SDPL+
Sbjct: 61 YREKK--TALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGR---SESSDPLE 115
Query: 120 IVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGE-AHECRFSAGPKVN 178
+V+TG Y KP+LSAQP P V +G +V L C S+ ++D + L +EGE H ++ P
Sbjct: 116 LVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHAR 175
Query: 179 GTFQADFPLGPATHGGT--YRCFGSFRDSPYEWSNSSDPLLVSVTG 222
G+ +A F +GP + YRC+ +SPYEWS SD L + V G
Sbjct: 176 GSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLG 221
Score = 30.8 bits (68), Expect = 1.9
Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Query: 278 DQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITR--PSQRPKTPPTDIIVYT 333
D+++ +R ++E + + PQ+VTY QL H + +R+ T PSQ +P I T
Sbjct: 591 DRQAEEDRQMDTEAAASEAPQDVTYAQL-HSLTLRREATEPPPSQEGPSPAVPSIYAT 647
>gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 1 [Homo sapiens]
Length = 650
Score = 194 bits (492), Expect = 1e-49
Identities = 131/364 (35%), Positives = 191/364 (52%), Gaps = 45/364 (12%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIG-EHHDGVSK 82
GV +KPSL PG +V EET+ LQC SD + F+L+++G+ +D L L G + G+S+
Sbjct: 221 GVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGE-RDFLQLAGAQPQAGLSQ 279
Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITG-LYEKPSLSAQPGPTVLA 141
ANF++GP+ + G YRCYG+ S + SAPSDPLDI+I G Y++ SLS QPGPTV +
Sbjct: 280 ANFTLGPVSRSYGGQYRCYGAHNLSS-EWSAPSDPLDILIAGQFYDRVSLSVQPGPTVAS 338
Query: 142 GESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPAT--HGGTYRCF 199
GE+VTL C S+ + L++EG A + + +QA+FP+GP T H GTYRC+
Sbjct: 339 GENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCY 398
Query: 200 GSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGNP-----------------R 242
GS PY ++ SDPL + V+G PS SPT + T P R
Sbjct: 399 GSQSSKPYLLTHPSDPLELVVSG-PSGGPSSPTTGPTSTSGPEDQPLTPTGSDPQSGLGR 457
Query: 243 HLHILIGTSVVIILFILLFFLL-----HR-----WCSNKKNAAVMDQESA--------GN 284
HL ++IG V +IL +LL LL HR W S ++ A A G
Sbjct: 458 HLGVVIGILVAVILLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGL 517
Query: 285 RTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKV 344
+ +S +D Q +E Y + H + + ++ P + Y E+ ++ R ++
Sbjct: 518 QWRSSPAADAQ--EENLYAAVKH-TQPEDGVEMDTRSPHDEDPQAVTYAEVKHSRPRREM 574
Query: 345 VSCP 348
S P
Sbjct: 575 ASPP 578
Score = 145 bits (367), Expect = 4e-35
Identities = 83/202 (41%), Positives = 119/202 (58%), Gaps = 4/202 (1%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEHHD-GVSK 82
G + KP+L A P +V S VILQC S V F+ F L +EG+ + L + H G S+
Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179
Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAG 142
A FS+GP+ YRCY ++SPY+ S PSD L++++ G+ +KPSLS QPGP V
Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239
Query: 143 ESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPA--THGGTYRCFG 200
E++TL C S + Y+ + L ++GE + + G QA+F LGP ++GG YRC+G
Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYG 299
Query: 201 SFRDSPYEWSNSSDPLLVSVTG 222
+ S EWS SDPL + + G
Sbjct: 300 AHNLSS-EWSAPSDPLDILIAG 320
Score = 120 bits (302), Expect = 1e-27
Identities = 81/226 (35%), Positives = 117/226 (51%), Gaps = 9/226 (3%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
M+ ++ + C+G L G KP+L A PG ++ V L+C + + L
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCY-GSVTHSPYQLSAPSDPLD 119
+RE K L + + V K F I + + AG YRCY GS T S SDPL+
Sbjct: 61 YREKK--TALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGR---SESSDPLE 115
Query: 120 IVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGE-AHECRFSAGPKVN 178
+V+TG Y KP+LSAQP P V +G +V L C S+ ++D + L +EGE H ++ P
Sbjct: 116 LVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHAR 175
Query: 179 GTFQADFPLGPATHGGT--YRCFGSFRDSPYEWSNSSDPLLVSVTG 222
G+ +A F +GP + YRC+ +SPYEWS SD L + V G
Sbjct: 176 GSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLG 221
Score = 30.8 bits (68), Expect = 1.9
Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Query: 278 DQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITR--PSQRPKTPPTDIIVYT 333
D+++ +R ++E + + PQ+VTY QL H + +R+ T PSQ +P I T
Sbjct: 590 DRQAEEDRQMDTEAAASEAPQDVTYAQL-HSLTLRREATEPPPSQEGPSPAVPSIYAT 646
>gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 2 [Homo sapiens]
Length = 652
Score = 193 bits (490), Expect = 2e-49
Identities = 131/364 (35%), Positives = 190/364 (52%), Gaps = 43/364 (11%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIG-EHHDGVSK 82
GV +KPSL PG +V EET+ LQC SD + F+L+++G+ +D L L G + G+S+
Sbjct: 221 GVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGE-RDFLQLAGAQPQAGLSQ 279
Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITG-LYEKPSLSAQPGPTVLA 141
ANF++GP+ + G YRCYG+ S + SAPSDPLDI+I G Y++ SLS QPGPTV +
Sbjct: 280 ANFTLGPVSRSYGGQYRCYGAHNLSS-EWSAPSDPLDILIAGQFYDRVSLSVQPGPTVAS 338
Query: 142 GESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPAT--HGGTYRCF 199
GE+VTL C S+ + L++EG A + + +QA+FP+GP T H GTYRC+
Sbjct: 339 GENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCY 398
Query: 200 GSFRDSPYEWSNSSDPLLVSV---TGNPSNSWPSPTEPSS--------------KTGNPR 242
GS PY ++ SDPL + V +G PS+ PT S+ ++G R
Sbjct: 399 GSQSSKPYLLTHPSDPLELVVSGPSGGPSSPTTGPTSTSAGPEDQPLTPTGSDPQSGLGR 458
Query: 243 HLHILIGTSVVIILFILLFFLL-----HR-----WCSNKKNAAVMDQESA--------GN 284
HL ++IG V +IL +LL LL HR W S ++ A A G
Sbjct: 459 HLGVVIGILVAVILLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGL 518
Query: 285 RTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKV 344
+ +S +D Q +E Y + H Q P + Y E+ ++ R ++
Sbjct: 519 QWRSSPAADAQ--EENLYAAVKHTQPEDGVEMDTRQSPHDEDPQAVTYAEVKHSRPRREM 576
Query: 345 VSCP 348
S P
Sbjct: 577 ASPP 580
Score = 145 bits (367), Expect = 4e-35
Identities = 83/202 (41%), Positives = 119/202 (58%), Gaps = 4/202 (1%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEHHD-GVSK 82
G + KP+L A P +V S VILQC S V F+ F L +EG+ + L + H G S+
Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179
Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAG 142
A FS+GP+ YRCY ++SPY+ S PSD L++++ G+ +KPSLS QPGP V
Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239
Query: 143 ESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPA--THGGTYRCFG 200
E++TL C S + Y+ + L ++GE + + G QA+F LGP ++GG YRC+G
Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYG 299
Query: 201 SFRDSPYEWSNSSDPLLVSVTG 222
+ S EWS SDPL + + G
Sbjct: 300 AHNLSS-EWSAPSDPLDILIAG 320
Score = 120 bits (302), Expect = 1e-27
Identities = 81/226 (35%), Positives = 117/226 (51%), Gaps = 9/226 (3%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
M+ ++ + C+G L G KP+L A PG ++ V L+C + + L
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCY-GSVTHSPYQLSAPSDPLD 119
+RE K L + + V K F I + + AG YRCY GS T S SDPL+
Sbjct: 61 YREKK--TALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGR---SESSDPLE 115
Query: 120 IVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGE-AHECRFSAGPKVN 178
+V+TG Y KP+LSAQP P V +G +V L C S+ ++D + L +EGE H ++ P
Sbjct: 116 LVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHAR 175
Query: 179 GTFQADFPLGPATHGGT--YRCFGSFRDSPYEWSNSSDPLLVSVTG 222
G+ +A F +GP + YRC+ +SPYEWS SD L + V G
Sbjct: 176 GSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLG 221
Score = 30.8 bits (68), Expect = 1.9
Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Query: 278 DQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITR--PSQRPKTPPTDIIVYT 333
D+++ +R ++E + + PQ+VTY QL H + +R+ T PSQ +P I T
Sbjct: 592 DRQAEEDRQMDTEAAASEAPQDVTYAQL-HSLTLRREATEPPPSQEGPSPAVPSIYAT 648
>gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 3 [Homo sapiens]
Length = 651
Score = 192 bits (489), Expect = 3e-49
Identities = 130/364 (35%), Positives = 193/364 (53%), Gaps = 44/364 (12%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIG-EHHDGVSK 82
GV +KPSL PG +V EET+ LQC SD + F+L+++G+ +D L L G + G+S+
Sbjct: 221 GVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGE-RDFLQLAGAQPQAGLSQ 279
Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITG-LYEKPSLSAQPGPTVLA 141
ANF++GP+ + G YRCYG+ S + SAPSDPLDI+I G Y++ SLS QPGPTV +
Sbjct: 280 ANFTLGPVSRSYGGQYRCYGAHNLSS-EWSAPSDPLDILIAGQFYDRVSLSVQPGPTVAS 338
Query: 142 GESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPAT--HGGTYRCF 199
GE+VTL C S+ + L++EG A + + +QA+FP+GP T H GTYRC+
Sbjct: 339 GENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCY 398
Query: 200 GSFRDSPYEWSNSSDPLLVSV---TGNPSNSWPSPTEPSS--------------KTGNPR 242
GS PY ++ SDPL + V +G PS+ PT S+ ++G R
Sbjct: 399 GSQSSKPYLLTHPSDPLELVVSGPSGGPSSPTTGPTSTSAGPEDQPLTPTGSDPQSGLGR 458
Query: 243 HLHILIGTSVVIILFILLFFLL-----HR-----WCSNKKNAAVMDQESA--------GN 284
HL ++IG V +IL +LL LL HR W S ++ A A G
Sbjct: 459 HLGVVIGILVAVILLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGL 518
Query: 285 RTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKV 344
+ +S +D Q +E Y + H + + ++ P + Y E+ ++ R ++
Sbjct: 519 QWRSSPAADAQ--EENLYAAVKH-TQPEDGVEMDTRSPHDEDPQAVTYAEVKHSRPRREM 575
Query: 345 VSCP 348
S P
Sbjct: 576 ASPP 579
Score = 145 bits (367), Expect = 4e-35
Identities = 83/202 (41%), Positives = 119/202 (58%), Gaps = 4/202 (1%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEHHD-GVSK 82
G + KP+L A P +V S VILQC S V F+ F L +EG+ + L + H G S+
Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179
Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAG 142
A FS+GP+ YRCY ++SPY+ S PSD L++++ G+ +KPSLS QPGP V
Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239
Query: 143 ESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPA--THGGTYRCFG 200
E++TL C S + Y+ + L ++GE + + G QA+F LGP ++GG YRC+G
Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYG 299
Query: 201 SFRDSPYEWSNSSDPLLVSVTG 222
+ S EWS SDPL + + G
Sbjct: 300 AHNLSS-EWSAPSDPLDILIAG 320
Score = 120 bits (302), Expect = 1e-27
Identities = 81/226 (35%), Positives = 117/226 (51%), Gaps = 9/226 (3%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
M+ ++ + C+G L G KP+L A PG ++ V L+C + + L
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCY-GSVTHSPYQLSAPSDPLD 119
+RE K L + + V K F I + + AG YRCY GS T S SDPL+
Sbjct: 61 YREKK--TALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGR---SESSDPLE 115
Query: 120 IVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGE-AHECRFSAGPKVN 178
+V+TG Y KP+LSAQP P V +G +V L C S+ ++D + L +EGE H ++ P
Sbjct: 116 LVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHAR 175
Query: 179 GTFQADFPLGPATHGGT--YRCFGSFRDSPYEWSNSSDPLLVSVTG 222
G+ +A F +GP + YRC+ +SPYEWS SD L + V G
Sbjct: 176 GSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLG 221
Score = 30.8 bits (68), Expect = 1.9
Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Query: 278 DQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITR--PSQRPKTPPTDIIVYT 333
D+++ +R ++E + + PQ+VTY QL H + +R+ T PSQ +P I T
Sbjct: 591 DRQAEEDRQMDTEAAASEAPQDVTYAQL-HSLTLRREATEPPPSQEGPSPAVPSIYAT 647
>gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B,
member 2 isoform 1 [Homo sapiens]
Length = 598
Score = 190 bits (482), Expect = 2e-48
Identities = 132/378 (34%), Positives = 184/378 (48%), Gaps = 68/378 (17%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEHHD-GVSK 82
GV +KPSL PG +V E++ LQC SDV ++ F+L++EG+ +D L G G+S+
Sbjct: 220 GVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVLYKEGE-RDLRQLPGRQPQAGLSQ 278
Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITG-LYEKPSLSAQPGPTVLA 141
ANF++GP+ + G YRCYG+ S + SAPSDPLDI+ITG + P +S QPGPTV +
Sbjct: 279 ANFTLGPVSRSYGGQYRCYGAHNLSS-ECSAPSDPLDILITGQIRGTPFISVQPGPTVAS 337
Query: 142 GESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPAT--HGGTYRCF 199
GE+VTL C S + + L++ G A +QA+FP+ P T H GTYRC+
Sbjct: 338 GENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHAGTYRCY 397
Query: 200 GSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGNP-----------------R 242
GS PY S+ S+PL + V+G S P PT P S P R
Sbjct: 398 GSLNSDPYLLSHPSEPLELVVSGPSMGSSPPPTGPISTPAGPEDQPLTPTGSDPQSGLGR 457
Query: 243 HLHILIGTSVVIILFILLFFLL-----HR-----WCSNKKNA------------------ 274
HL ++IG V ++L +LL LL HR W S ++ A
Sbjct: 458 HLGVVIGILVAVVLLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGL 517
Query: 275 ------AVMDQES---AGNRTANSEDSDEQD--------PQEVTYTQLNHCVFTQRKITR 317
A QE A + ED E D PQ+VTY QL+ ++
Sbjct: 518 QWRSSPAADAQEENLYAAVKDTQPEDGVEMDTRAAASEAPQDVTYAQLHSLTLRRKATEP 577
Query: 318 PSQRPKTPPTDIIVYTEL 335
P + + PP + +Y L
Sbjct: 578 PPSQEREPPAEPSIYATL 595
Score = 144 bits (364), Expect = 9e-35
Identities = 86/202 (42%), Positives = 119/202 (58%), Gaps = 4/202 (1%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEHHD-GVSK 82
G + KP+L A P +V S V LQC S V F F+L +EG+ + L + H G S+
Sbjct: 119 GAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSR 178
Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAG 142
A FS+GP+ + ++RCYG +SPY S+PSD L++++ G+ +KPSLS QPGP V G
Sbjct: 179 AIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPG 238
Query: 143 ESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPA--THGGTYRCFG 200
ES+TL C S YD + L +EGE + G QA+F LGP ++GG YRC+G
Sbjct: 239 ESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCYG 298
Query: 201 SFRDSPYEWSNSSDPLLVSVTG 222
+ S E S SDPL + +TG
Sbjct: 299 AHNLSS-ECSAPSDPLDILITG 319
Score = 109 bits (272), Expect = 4e-24
Identities = 74/225 (32%), Positives = 112/225 (49%), Gaps = 8/225 (3%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
M+ +V + C+G L G KP+L A P ++ V L C + + + L
Sbjct: 1 MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRL 60
Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
+RE K + I + V F I + + G Y C +S + S SDPL +
Sbjct: 61 YREKKSASWITRI--RPELVKNGQFHIPSITWEHTGRYGCQ---YYSRARWSELSDPLVL 115
Query: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREG-EAHECRFSAGPKVNG 179
V+TG Y KP+LSAQP P V +G VTL C S+ ++ + L +EG E H ++ P G
Sbjct: 116 VMTGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARG 175
Query: 180 TFQADFPLGPAT--HGGTYRCFGSFRDSPYEWSNSSDPLLVSVTG 222
+ +A F +GP + ++RC+G +SPY WS+ SD L + V G
Sbjct: 176 SSRAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPG 220
>gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B,
member 2 isoform 2 [Homo sapiens]
Length = 597
Score = 189 bits (481), Expect = 2e-48
Identities = 132/377 (35%), Positives = 186/377 (49%), Gaps = 67/377 (17%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEHHD-GVSK 82
GV +KPSL PG +V E++ LQC SDV ++ F+L++EG+ +D L G G+S+
Sbjct: 220 GVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVLYKEGE-RDLRQLPGRQPQAGLSQ 278
Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITG-LYEKPSLSAQPGPTVLA 141
ANF++GP+ + G YRCYG+ S + SAPSDPLDI+ITG + P +S QPGPTV +
Sbjct: 279 ANFTLGPVSRSYGGQYRCYGAHNLSS-ECSAPSDPLDILITGQIRGTPFISVQPGPTVAS 337
Query: 142 GESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPAT--HGGTYRCF 199
GE+VTL C S + + L++ G A +QA+FP+ P T H GTYRC+
Sbjct: 338 GENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHAGTYRCY 397
Query: 200 GSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSS----------------KTGNPRH 243
GS PY S+ S+PL + V+G S P PT P S ++G RH
Sbjct: 398 GSLNSDPYLLSHPSEPLELVVSGPSMGSSPPPTGPISTPGPEDQPLTPTGSDPQSGLGRH 457
Query: 244 LHILIGTSVVIILFILLFFLL-----HR-----WCSNKKNA------------------- 274
L ++IG V ++L +LL LL HR W S ++ A
Sbjct: 458 LGVVIGILVAVVLLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGLQ 517
Query: 275 -----AVMDQES---AGNRTANSEDSDEQD--------PQEVTYTQLNHCVFTQRKITRP 318
A QE A + ED E D PQ+VTY QL+ ++ P
Sbjct: 518 WRSSPAADAQEENLYAAVKDTQPEDGVEMDTRAAASEAPQDVTYAQLHSLTLRRKATEPP 577
Query: 319 SQRPKTPPTDIIVYTEL 335
+ + PP + +Y L
Sbjct: 578 PSQEREPPAEPSIYATL 594
Score = 144 bits (364), Expect = 9e-35
Identities = 86/202 (42%), Positives = 119/202 (58%), Gaps = 4/202 (1%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEHHD-GVSK 82
G + KP+L A P +V S V LQC S V F F+L +EG+ + L + H G S+
Sbjct: 119 GAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSR 178
Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAG 142
A FS+GP+ + ++RCYG +SPY S+PSD L++++ G+ +KPSLS QPGP V G
Sbjct: 179 AIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPG 238
Query: 143 ESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPA--THGGTYRCFG 200
ES+TL C S YD + L +EGE + G QA+F LGP ++GG YRC+G
Sbjct: 239 ESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCYG 298
Query: 201 SFRDSPYEWSNSSDPLLVSVTG 222
+ S E S SDPL + +TG
Sbjct: 299 AHNLSS-ECSAPSDPLDILITG 319
Score = 109 bits (272), Expect = 4e-24
Identities = 74/225 (32%), Positives = 112/225 (49%), Gaps = 8/225 (3%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
M+ +V + C+G L G KP+L A P ++ V L C + + + L
Sbjct: 1 MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRL 60
Query: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
+RE K + I + V F I + + G Y C +S + S SDPL +
Sbjct: 61 YREKKSASWITRI--RPELVKNGQFHIPSITWEHTGRYGCQ---YYSRARWSELSDPLVL 115
Query: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREG-EAHECRFSAGPKVNG 179
V+TG Y KP+LSAQP P V +G VTL C S+ ++ + L +EG E H ++ P G
Sbjct: 116 VMTGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARG 175
Query: 180 TFQADFPLGPAT--HGGTYRCFGSFRDSPYEWSNSSDPLLVSVTG 222
+ +A F +GP + ++RC+G +SPY WS+ SD L + V G
Sbjct: 176 SSRAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPG 220
>gi|125987593 leukocyte immunoglobulin-like receptor, subfamily B,
member 5 isoform 3 [Homo sapiens]
Length = 491
Score = 183 bits (465), Expect = 2e-46
Identities = 129/372 (34%), Positives = 187/372 (50%), Gaps = 62/372 (16%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEHHD-GVSK 82
GV RKPSLL G +V ++ LQC SDV ++ F+L++EG+ D + G+ G+S+
Sbjct: 119 GVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEH-DLVQGSGQQPQAGLSQ 177
Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLY-EKPSLSAQPGPTVLA 141
ANF++GP+ + G YRCYG+ SP + SAPSDPLDI+I GL + P+LS QPGP V +
Sbjct: 178 ANFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVAS 236
Query: 142 GESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPAT--HGGTYRCF 199
GE+VTL C S D + L++EG AH + QA+F + P T GGTYRC+
Sbjct: 237 GENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCY 296
Query: 200 GSFRDSPYEWSNSSDPLLVSVTG-------NPSNSWPSPTEPSS----------KTGNPR 242
+ R PY S+ S P + V+G +P+ S P+P P ++G R
Sbjct: 297 SAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLGR 356
Query: 243 HLHILIGTSV--VIILFILLFFLL-HRWCSNKK--------------------------- 272
HL ++ G SV V++LF+LLF LL HR S +
Sbjct: 357 HLGVVTGVSVAFVLLLFLLLFLLLRHRHQSKHRTSAHFYRPAGAAGPEPKDQGLQKRASP 416
Query: 273 ---------NAAVMDQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPK 323
NAAV D + ++ + + PQ+VTY QL+ + P + +
Sbjct: 417 VADIQEEILNAAVKDTQPKDGVEMDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQER 476
Query: 324 TPPTDIIVYTEL 335
PP + +Y L
Sbjct: 477 EPPAEPSIYAPL 488
Score = 122 bits (305), Expect = 6e-28
Identities = 85/254 (33%), Positives = 123/254 (48%), Gaps = 18/254 (7%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
M+L + + C+G + G KP+L A P ++ + V L C + E + L
Sbjct: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
Query: 61 HREG-----KFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPS 115
+EG K ++ L + +KA F I + D AG YRCY +P S PS
Sbjct: 61 DKEGLPWARKRQNPL-------EPGAKAKFHIPSTVYDSAGRYRCY---YETPAGWSEPS 110
Query: 116 DPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGP 175
DPL++V TG+ KPSL G V G S+TL C S YD++ L +EGE + S
Sbjct: 111 DPLELVATGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQ 170
Query: 176 KVNGTFQADFPLGPA--THGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTE 233
G QA+F LGP +HGG YRC+G+ SP WS SDPL + + G + +
Sbjct: 171 PQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQ 229
Query: 234 PSSKTGNPRHLHIL 247
P K + ++ +L
Sbjct: 230 PGPKVASGENVTLL 243
>gi|125987591 leukocyte immunoglobulin-like receptor, subfamily B,
member 5 isoform 1 [Homo sapiens]
Length = 591
Score = 183 bits (465), Expect = 2e-46
Identities = 129/372 (34%), Positives = 187/372 (50%), Gaps = 62/372 (16%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEHHD-GVSK 82
GV RKPSLL G +V ++ LQC SDV ++ F+L++EG+ D + G+ G+S+
Sbjct: 219 GVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEH-DLVQGSGQQPQAGLSQ 277
Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLY-EKPSLSAQPGPTVLA 141
ANF++GP+ + G YRCYG+ SP + SAPSDPLDI+I GL + P+LS QPGP V +
Sbjct: 278 ANFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVAS 336
Query: 142 GESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPAT--HGGTYRCF 199
GE+VTL C S D + L++EG AH + QA+F + P T GGTYRC+
Sbjct: 337 GENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCY 396
Query: 200 GSFRDSPYEWSNSSDPLLVSVTG-------NPSNSWPSPTEPSS----------KTGNPR 242
+ R PY S+ S P + V+G +P+ S P+P P ++G R
Sbjct: 397 SAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLGR 456
Query: 243 HLHILIGTSV--VIILFILLFFLL-HRWCSNKK--------------------------- 272
HL ++ G SV V++LF+LLF LL HR S +
Sbjct: 457 HLGVVTGVSVAFVLLLFLLLFLLLRHRHQSKHRTSAHFYRPAGAAGPEPKDQGLQKRASP 516
Query: 273 ---------NAAVMDQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPK 323
NAAV D + ++ + + PQ+VTY QL+ + P + +
Sbjct: 517 VADIQEEILNAAVKDTQPKDGVEMDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQER 576
Query: 324 TPPTDIIVYTEL 335
PP + +Y L
Sbjct: 577 EPPAEPSIYAPL 588
Score = 117 bits (292), Expect = 2e-26
Identities = 80/227 (35%), Positives = 114/227 (50%), Gaps = 5/227 (2%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWS-DVRFEHFLLHREGKFKDTLHLIGEHHDGVSK 82
G + +P+LLA P +V S V LQC + D L+ E K TL+ + G S+
Sbjct: 119 GFYAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLYS-QKLPKGPSQ 177
Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAG 142
A F +GP+ +RCY +P S PSD L+I++ G+ KPSL G V G
Sbjct: 178 ALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARG 237
Query: 143 ESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPA--THGGTYRCFG 200
S+TL C S YD++ L +EGE + S G QA+F LGP +HGG YRC+G
Sbjct: 238 GSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYG 297
Query: 201 SFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGNPRHLHIL 247
+ SP WS SDPL + + G + +P K + ++ +L
Sbjct: 298 AHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLL 343
Score = 105 bits (263), Expect = 5e-23
Identities = 74/229 (32%), Positives = 108/229 (47%), Gaps = 17/229 (7%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
M+L + + C+G + G KP+L A P ++ + V L C + E + L
Sbjct: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
Query: 61 HREG-----KFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPS 115
+EG K ++ L + +KA F I + D AG YRCY +P S PS
Sbjct: 61 DKEGLPWARKRQNPL-------EPGAKAKFHIPSTVYDSAGRYRCY---YETPAGWSEPS 110
Query: 116 DPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGP 175
DPL++V TG Y +P+L A P P V +G +VTL C + + L E + +
Sbjct: 111 DPLELVATGFYAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLYSQK 170
Query: 176 KVNGTFQADFPLGPATHG--GTYRCFGSFRDSPYEWSNSSDPLLVSVTG 222
G QA FP+GP T +RC+ +R +P WSN SD L + V G
Sbjct: 171 LPKGPSQALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPG 219
>gi|5803070 leukocyte immunoglobulin-like receptor, subfamily B,
member 5 isoform 2 [Homo sapiens]
Length = 590
Score = 182 bits (461), Expect = 5e-46
Identities = 131/371 (35%), Positives = 190/371 (51%), Gaps = 61/371 (16%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEHHD-GVSK 82
GV RKPSLL G +V ++ LQC SDV ++ F+L++EG+ D + G+ G+S+
Sbjct: 219 GVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEH-DLVQGSGQQPQAGLSQ 277
Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLY-EKPSLSAQPGPTVLA 141
ANF++GP+ + G YRCYG+ SP + SAPSDPLDI+I GL + P+LS QPGP V +
Sbjct: 278 ANFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVAS 336
Query: 142 GESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPAT--HGGTYRCF 199
GE+VTL C S D + L++EG AH + QA+F + P T GGTYRC+
Sbjct: 337 GENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCY 396
Query: 200 GSFRDSPYEWSNSSDPLLVSVTG-------NPSNSWPSP---TEPSSKTG-NP-----RH 243
+ R PY S+ S P + V+G +P+ S P+P +P + TG +P RH
Sbjct: 397 SAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPGPEDQPLTPTGLDPQSGLGRH 456
Query: 244 LHILIGTSV--VIILFILLFFLL-HRWCSNKK---------------------------- 272
L ++ G SV V++LF+LLF LL HR S +
Sbjct: 457 LGVVTGVSVAFVLLLFLLLFLLLRHRHQSKHRTSAHFYRPAGAAGPEPKDQGLQKRASPV 516
Query: 273 --------NAAVMDQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKT 324
NAAV D + ++ + + PQ+VTY QL+ + P + +
Sbjct: 517 ADIQEEILNAAVKDTQPKDGVEMDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQERE 576
Query: 325 PPTDIIVYTEL 335
PP + +Y L
Sbjct: 577 PPAEPSIYAPL 587
Score = 117 bits (292), Expect = 2e-26
Identities = 80/227 (35%), Positives = 114/227 (50%), Gaps = 5/227 (2%)
Query: 24 GVHRKPSLLAHPGRLVKSEETVILQCWS-DVRFEHFLLHREGKFKDTLHLIGEHHDGVSK 82
G + +P+LLA P +V S V LQC + D L+ E K TL+ + G S+
Sbjct: 119 GFYAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLYS-QKLPKGPSQ 177
Query: 83 ANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAG 142
A F +GP+ +RCY +P S PSD L+I++ G+ KPSL G V G
Sbjct: 178 ALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARG 237
Query: 143 ESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPA--THGGTYRCFG 200
S+TL C S YD++ L +EGE + S G QA+F LGP +HGG YRC+G
Sbjct: 238 GSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYG 297
Query: 201 SFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGNPRHLHIL 247
+ SP WS SDPL + + G + +P K + ++ +L
Sbjct: 298 AHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLL 343
Score = 105 bits (263), Expect = 5e-23
Identities = 74/229 (32%), Positives = 108/229 (47%), Gaps = 17/229 (7%)
Query: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
M+L + + C+G + G KP+L A P ++ + V L C + E + L
Sbjct: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
Query: 61 HREG-----KFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPS 115
+EG K ++ L + +KA F I + D AG YRCY +P S PS
Sbjct: 61 DKEGLPWARKRQNPL-------EPGAKAKFHIPSTVYDSAGRYRCY---YETPAGWSEPS 110
Query: 116 DPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGP 175
DPL++V TG Y +P+L A P P V +G +VTL C + + L E + +
Sbjct: 111 DPLELVATGFYAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLYSQK 170
Query: 176 KVNGTFQADFPLGPATHG--GTYRCFGSFRDSPYEWSNSSDPLLVSVTG 222
G QA FP+GP T +RC+ +R +P WSN SD L + V G
Sbjct: 171 LPKGPSQALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPG 219
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,435,991
Number of Sequences: 37866
Number of extensions: 763372
Number of successful extensions: 2996
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 75
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 2314
Number of HSP's gapped (non-prelim): 239
length of query: 348
length of database: 18,247,518
effective HSP length: 103
effective length of query: 245
effective length of database: 14,347,320
effective search space: 3515093400
effective search space used: 3515093400
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.