BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|134268644 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 precursor [Homo sapiens] (444 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|134268644 killer cell immunoglobulin-like receptor, three dom... 929 0.0 gi|134268642 killer cell immunoglobulin-like receptor, three dom... 786 0.0 gi|134133244 killer cell immunoglobulin-like receptor, three dom... 742 0.0 gi|46488946 killer cell immunoglobulin-like receptor, three doma... 639 0.0 gi|134304833 killer cell immunoglobulin-like receptor, two domai... 575 e-164 gi|71143139 killer cell immunoglobulin-like receptor, two domain... 568 e-162 gi|110611923 killer cell immunoglobulin-like receptor, two domai... 567 e-162 gi|6912472 killer cell immunoglobulin-like receptor, two domains... 493 e-139 gi|62632748 killer-cell Ig-like receptor [Homo sapiens] 487 e-137 gi|116517309 killer cell immunoglobulin-like receptor, two domai... 482 e-136 gi|7657277 killer cell immunoglobulin-like receptor, two domains... 482 e-136 gi|134304835 killer cell immunoglobulin-like receptor, two domai... 471 e-133 gi|6912474 killer cell immunoglobulin-like receptor, two domains... 456 e-128 gi|11968154 killer cell immunoglobulin-like receptor, two domain... 430 e-120 gi|66267727 killer cell immunoglobulin-like receptor, two domain... 419 e-117 gi|124107606 killer cell immunoglobulin-like receptor, two domai... 409 e-114 gi|124107610 killer cell immunoglobulin-like receptor, two domai... 345 6e-95 gi|71143143 killer cell immunoglobulin-like receptor, two domain... 305 5e-83 gi|124107604 killer cell immunoglobulin-like receptor, two domai... 298 9e-81 gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B... 269 3e-72 gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B... 269 4e-72 gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B... 248 1e-65 gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B... 247 1e-65 gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B... 239 4e-63 gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B... 239 4e-63 gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B... 239 5e-63 gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B... 239 5e-63 gi|110611910 leukocyte immunoglobulin-like receptor, subfamily A... 239 5e-63 gi|125987593 leukocyte immunoglobulin-like receptor, subfamily B... 228 8e-60 gi|47519953 leukocyte immunoglobulin-like receptor subfamily A m... 225 7e-59 >gi|134268644 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 precursor [Homo sapiens] Length = 444 Score = 929 bits (2402), Expect = 0.0 Identities = 444/444 (100%), Positives = 444/444 (100%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML Sbjct: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 Query: 61 YKEDRIHIPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGN 120 YKEDRIHIPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGN Sbjct: 61 YKEDRIHIPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGN 120 Query: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANF 180 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANF Sbjct: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANF 180 Query: 181 SIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESV 240 SIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESV Sbjct: 181 SIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESV 240 Query: 241 TLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHS 300 TLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHS Sbjct: 241 TLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHS 300 Query: 301 PYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNPRHLHILIGTSVVIILFILLLFFLL 360 PYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNPRHLHILIGTSVVIILFILLLFFLL Sbjct: 301 PYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNPRHLHILIGTSVVIILFILLLFFLL 360 Query: 361 HLWCSNKKNAAVMDQEPAGNRTANSEDSDEQDPEEVTYAQLDHCVFTQRKITRPSQRPKT 420 HLWCSNKKNAAVMDQEPAGNRTANSEDSDEQDPEEVTYAQLDHCVFTQRKITRPSQRPKT Sbjct: 361 HLWCSNKKNAAVMDQEPAGNRTANSEDSDEQDPEEVTYAQLDHCVFTQRKITRPSQRPKT 420 Query: 421 PPTDTILYTELPNAKPRSKVVSCP 444 PPTDTILYTELPNAKPRSKVVSCP Sbjct: 421 PPTDTILYTELPNAKPRSKVVSCP 444 >gi|134268642 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 precursor [Homo sapiens] Length = 455 Score = 786 bits (2031), Expect = 0.0 Identities = 380/444 (85%), Positives = 402/444 (90%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 MSL VVSMACVG FL+Q A P MGGQDKPFLSA PS VVPRGGHV L+CHYR FNNFML Sbjct: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 Query: 61 YKEDRIHIPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGN 120 YKEDR H+PIFHGRIFQESF M PVT AHAG Y CRGS PHS TGWSAPSNP+VIMVTGN Sbjct: 61 YKEDRSHVPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGN 120 Query: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANF 180 HRKPSLLAHPGPL+KSGE VILQCWSD+MFEHFFLH+EGIS+DPSRLVGQIHDGVSKANF Sbjct: 121 HRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANF 180 Query: 181 SIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESV 240 SIGP+M LAGTYRCYGSV H+PYQLSAPSDPLDIV+TG YEKPSLSAQPGP VQAGE+V Sbjct: 181 SIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGENV 240 Query: 241 TLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHS 300 TLSCSS SSYD+YHLSREG AHERRL AV KVNRTFQADFPLGPATHGGTYRCFGSFR Sbjct: 241 TLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPATHGGTYRCFGSFRAL 300 Query: 301 PYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNPRHLHILIGTSVVIILFILLLFFLL 360 P WS+ SDPLLVSVTGNPSSSWPSPTEPSSKSG RHLH+LIGTSVVI LFILLLFFLL Sbjct: 301 PCVWSNSSDPLLVSVTGNPSSSWPSPTEPSSKSGICRHLHVLIGTSVVIFLFILLLFFLL 360 Query: 361 HLWCSNKKNAAVMDQEPAGNRTANSEDSDEQDPEEVTYAQLDHCVFTQRKITRPSQRPKT 420 + WCSNKKNAAVMDQEPAG+RT N +DSDEQDP+EVTYAQLDHCVF QRKI+RPSQRPKT Sbjct: 361 YRWCSNKKNAAVMDQEPAGDRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISRPSQRPKT 420 Query: 421 PPTDTILYTELPNAKPRSKVVSCP 444 P TDT +YTELPNA+PRSKVVSCP Sbjct: 421 PLTDTSVYTELPNAEPRSKVVSCP 444 >gi|134133244 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1 [Homo sapiens] Length = 382 Score = 742 bits (1915), Expect = 0.0 Identities = 354/368 (96%), Positives = 357/368 (97%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 M LMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML Sbjct: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 Query: 61 YKEDRIHIPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGN 120 YKEDRIH+PIFHGRIFQE FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNP+VIMVTGN Sbjct: 61 YKEDRIHVPIFHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGN 120 Query: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANF 180 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKE ISKDPSRLVGQIHDGVSKANF Sbjct: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANF 180 Query: 181 SIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESV 240 SIG MM ALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTG YEKPSLSAQPGPKVQAGESV Sbjct: 181 SIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESV 240 Query: 241 TLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHS 300 TLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHS Sbjct: 241 TLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHS 300 Query: 301 PYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNPRHLHILIGTSVVIILFILLLFFLL 360 PYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGN RHLHILIGTSVV I F +LLFFLL Sbjct: 301 PYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFFLL 360 Query: 361 HLWCSNKK 368 H WCSNKK Sbjct: 361 HRWCSNKK 368 >gi|46488946 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 [Homo sapiens] Length = 410 Score = 639 bits (1648), Expect = 0.0 Identities = 313/425 (73%), Positives = 342/425 (80%), Gaps = 17/425 (4%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 MSLMVVSMACVG FL++ PH+GGQDKPFLSAWP VV G HVTL+C R FN F L Sbjct: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60 Query: 61 YKEDRIHIPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGN 120 KED + +P + RIF+ SF M PVT AHAG Y C SHPHSPTGWSAPSNPVVIMVTG Sbjct: 61 SKEDGMPVPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGV 120 Query: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANF 180 HRKPSLLAHPGPLVKSGE VILQCWSD+ FE F LH+EGI++DP RLVGQ+HD S+ N+ Sbjct: 121 HRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNY 180 Query: 181 SIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESV 240 S+GPM ALAGTYRC+GSVTH PY+LSAPSDPLDIVV G Y KPSLSAQPGP VQAGE+V Sbjct: 181 SMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGENV 240 Query: 241 TLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHS 300 TLSCSSRS +D+YHLSRE A E RL AV +VN TFQA+FPLGP THGG YRCFGSFR Sbjct: 241 TLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFRAL 300 Query: 301 PYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNPRHLHILIGTSVVIILFILLLFFLL 360 P+ WSDPSDPL VSVT GN RHLH+LIGTSVVII F +LLFFLL Sbjct: 301 PHAWSDPSDPLPVSVT-----------------GNSRHLHVLIGTSVVIIPFAILLFFLL 343 Query: 361 HLWCSNKKNAAVMDQEPAGNRTANSEDSDEQDPEEVTYAQLDHCVFTQRKITRPSQRPKT 420 H WC+NKKNA VMDQEPAGNRT N EDSDEQDP+EVTYAQL+HCVFTQRKITRPSQRPKT Sbjct: 344 HRWCANKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKT 403 Query: 421 PPTDT 425 PPTDT Sbjct: 404 PPTDT 408 >gi|134304833 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 precursor [Homo sapiens] Length = 348 Score = 575 bits (1482), Expect = e-164 Identities = 287/360 (79%), Positives = 304/360 (84%), Gaps = 17/360 (4%) Query: 85 VTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGERVILQC 144 V+ A G + +G+ PH G HRKPSLLAHPG LVKS E VILQC Sbjct: 6 VSMACVGFFLLQGAWPHE----------------GVHRKPSLLAHPGRLVKSEETVILQC 49 Query: 145 WSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYGSVTHTPY 204 WSD+ FEHF LH+EG KD L+G+ HDGVSKANFSIGPMM LAGTYRCYGSVTH+PY Sbjct: 50 WSDVRFEHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPY 109 Query: 205 QLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHER 264 QLSAPSDPLDIV+TG YEKPSLSAQPGP V AGESVTLSCSSRSSYDMYHLSREG AHE Sbjct: 110 QLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHEC 169 Query: 265 RLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSWP 324 R A KVN TFQADFPLGPATHGGTYRCFGSFR SPYEWS+ SDPLLVSVTGNPS+SWP Sbjct: 170 RFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWP 229 Query: 325 SPTEPSSKSGNPRHLHILIGTSVVIILFILLLFFLLHLWCSNKKNAAVMDQEPAGNRTAN 384 SPTEPSSK+GNPRHLHILIGTSVVIILFI LLFFLLH WCSNKKNAAVMDQE AGNRTAN Sbjct: 230 SPTEPSSKTGNPRHLHILIGTSVVIILFI-LLFFLLHRWCSNKKNAAVMDQESAGNRTAN 288 Query: 385 SEDSDEQDPEEVTYAQLDHCVFTQRKITRPSQRPKTPPTDTILYTELPNAKPRSKVVSCP 444 SEDSDEQDP+EVTY QL+HCVFTQRKITRPSQRPKTPPTD I+YTELPNA+ RSKVVSCP Sbjct: 289 SEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP 348 Score = 164 bits (414), Expect = 2e-40 Identities = 97/224 (43%), Positives = 131/224 (58%), Gaps = 7/224 (3%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 MSLMVVSMACVG FL+Q A PH G KP L A P +V V L+C RF +F+L Sbjct: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60 Query: 61 YKE----DRIH-IPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVI 115 ++E D +H I H + + +F++ P+ AG Y C GS HSP SAPS+P+ I Sbjct: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120 Query: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGV 175 ++TG + KPSL A PGP V +GE V L C S ++ + L +EG + + G +G Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT 180 Query: 176 SKANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTG 219 +A+F +GP GTYRC+GS +PY+ S SDPL + VTG Sbjct: 181 FQADFPLGP--ATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTG 222 >gi|71143139 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 isoform 2 [Homo sapiens] Length = 341 Score = 568 bits (1464), Expect = e-162 Identities = 272/318 (85%), Positives = 288/318 (90%) Query: 119 GNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKA 178 G HRKPSLLAHPGPLVKS E VILQCWSD+ F+HF LH+EG KD L+G+ HDGVSKA Sbjct: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 Query: 179 NFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGE 238 NFSIGPMM LAGTYRCYGSVTH+PYQLSAPSDPLDIV+TG YEKPSLSAQPGP V AGE Sbjct: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGE 143 Query: 239 SVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFR 298 SVTLSCSSRSSYDMYHLSREG AHERR A KVN TFQADFPLGPATHGGTYRCFGSFR Sbjct: 144 SVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFR 203 Query: 299 HSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNPRHLHILIGTSVVIILFILLLFF 358 SPYEWS+ SDPLLVSVTGNPS+SWPSPTEPSS++GNPRHLH+LIGTSVVIILFILLLFF Sbjct: 204 DSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSETGNPRHLHVLIGTSVVIILFILLLFF 263 Query: 359 LLHLWCSNKKNAAVMDQEPAGNRTANSEDSDEQDPEEVTYAQLDHCVFTQRKITRPSQRP 418 LLH WC NKKNA VMDQEPAGNRT N EDSDEQDP+EVTYAQL+HCVFTQRKITRPSQRP Sbjct: 264 LLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRP 323 Query: 419 KTPPTDTILYTELPNAKP 436 KTPPTD I+YTELPNA+P Sbjct: 324 KTPPTDIIVYTELPNAEP 341 Score = 163 bits (413), Expect = 3e-40 Identities = 101/244 (41%), Positives = 139/244 (56%), Gaps = 11/244 (4%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 MSLMVVSM CVG FL+Q A PH G KP L A P +V V L+C RF +F+L Sbjct: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 Query: 61 YKE----DRIH-IPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVI 115 ++E D +H I H + + +F++ P+ AG Y C GS HSP SAPS+P+ I Sbjct: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120 Query: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGV 175 ++TG + KPSL A PGP V +GE V L C S ++ + L +EG + + G +G Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGT 180 Query: 176 SKANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQ 235 +A+F +GP GTYRC+GS +PY+ S SDPL + VTG PS ++ P P Sbjct: 181 FQADFPLGP--ATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTG---NPS-NSWPSPTEP 234 Query: 236 AGES 239 + E+ Sbjct: 235 SSET 238 >gi|110611923 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 [Homo sapiens] Length = 348 Score = 567 bits (1462), Expect = e-162 Identities = 283/360 (78%), Positives = 302/360 (83%), Gaps = 17/360 (4%) Query: 85 VTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGERVILQC 144 V+ A G + +G+ PH G HRKPSLLAHPG LVKS E VILQC Sbjct: 6 VSMACVGFFLLQGAWPHE----------------GVHRKPSLLAHPGRLVKSEETVILQC 49 Query: 145 WSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYGSVTHTPY 204 WSD+MFEHF LH+EG+ D RL+G+ HDGVSKANFSI M LAGTYRCYGSVTH+PY Sbjct: 50 WSDVMFEHFLLHREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPY 109 Query: 205 QLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHER 264 Q+SAPSDPLDIV+ G YEKPSLSAQ GP V AGE+VTLSCSSRSSYDMYHLSREG AHER Sbjct: 110 QVSAPSDPLDIVIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHER 169 Query: 265 RLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSWP 324 RLPA KVN TFQADFPLGPATHGGTYRCFGSF SPYEWS SDPLLVSVTGNPS+SWP Sbjct: 170 RLPAGPKVNGTFQADFPLGPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWP 229 Query: 325 SPTEPSSKSGNPRHLHILIGTSVVIILFILLLFFLLHLWCSNKKNAAVMDQEPAGNRTAN 384 SPTEPSSK+GNPRHLHILIGTSVVIILFI LLFFLLH WCSNKKNAAVMDQE AGNRTAN Sbjct: 230 SPTEPSSKTGNPRHLHILIGTSVVIILFI-LLFFLLHRWCSNKKNAAVMDQESAGNRTAN 288 Query: 385 SEDSDEQDPEEVTYAQLDHCVFTQRKITRPSQRPKTPPTDTILYTELPNAKPRSKVVSCP 444 SEDSDEQDP+EVTY QL+HCVFTQRKITRPSQRPKTPPTD I+YTELPNA+ RSKVVSCP Sbjct: 289 SEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP 348 Score = 153 bits (386), Expect = 3e-37 Identities = 92/224 (41%), Positives = 127/224 (56%), Gaps = 7/224 (3%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 MSL+VVSMACVG FL+Q A PH G KP L A P +V V L+C F +F+L Sbjct: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60 Query: 61 YKEDRIH-----IPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVI 115 ++E + I H + + +F++S +T AG Y C GS HSP SAPS+P+ I Sbjct: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120 Query: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGV 175 ++ G + KPSL A GP V +GE V L C S ++ + L +EG + + G +G Sbjct: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGT 180 Query: 176 SKANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTG 219 +A+F +GP GTYRC+GS +PY+ S SDPL + VTG Sbjct: 181 FQADFPLGP--ATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTG 222 >gi|6912472 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2 precursor [Homo sapiens] Length = 304 Score = 493 bits (1270), Expect = e-139 Identities = 244/315 (77%), Positives = 261/315 (82%), Gaps = 16/315 (5%) Query: 85 VTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGERVILQC 144 V+ A G + +G+ PH G HRKPSLLAHPGPLVKS E VILQC Sbjct: 6 VSMACVGFFLLQGAWPHE----------------GVHRKPSLLAHPGPLVKSEETVILQC 49 Query: 145 WSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYGSVTHTPY 204 WSD+ FEHF LH+EG KD L+G+ HDGVSKANFSIGPMM LAGTYRCYGSVTH+PY Sbjct: 50 WSDVRFEHFLLHREGKYKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPY 109 Query: 205 QLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHER 264 QLSAPSDPLDIV+TG YEKPSLSAQPGP V AGESVTLSCSSRSSYDMYHLSREG AHER Sbjct: 110 QLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHER 169 Query: 265 RLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSWP 324 R A KVN TFQADFPLGPATHGGTYRCFGSFR SPYEWS+ SDPLLVSVTGNPS+SWP Sbjct: 170 RFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWP 229 Query: 325 SPTEPSSKSGNPRHLHILIGTSVVIILFILLLFFLLHLWCSNKKNAAVMDQEPAGNRTAN 384 SPTEPSSK+GNPRHLH+LIGTSVV I F +LLFFLLH WCSNKKNAAVMDQEPAGNRT N Sbjct: 230 SPTEPSSKTGNPRHLHVLIGTSVVKIPFTILLFFLLHRWCSNKKNAAVMDQEPAGNRTVN 289 Query: 385 SEDSDEQDPEEVTYA 399 SEDSDEQD +EV+YA Sbjct: 290 SEDSDEQDHQEVSYA 304 Score = 164 bits (415), Expect = 1e-40 Identities = 97/224 (43%), Positives = 131/224 (58%), Gaps = 7/224 (3%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 MSLMVVSMACVG FL+Q A PH G KP L A P +V V L+C RF +F+L Sbjct: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFEHFLL 60 Query: 61 YKE----DRIH-IPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVI 115 ++E D +H I H + + +F++ P+ AG Y C GS HSP SAPS+P+ I Sbjct: 61 HREGKYKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120 Query: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGV 175 ++TG + KPSL A PGP V +GE V L C S ++ + L +EG + + G +G Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGT 180 Query: 176 SKANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTG 219 +A+F +GP GTYRC+GS +PY+ S SDPL + VTG Sbjct: 181 FQADFPLGP--ATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTG 222 >gi|62632748 killer-cell Ig-like receptor [Homo sapiens] Length = 328 Score = 487 bits (1253), Expect = e-137 Identities = 238/316 (75%), Positives = 258/316 (81%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 MSLMV+SMACVG FL+Q A H GGQDKPFLSAWPS VV G HV L+C R FN F L Sbjct: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPFLSAWPSPVVSEGEHVALQCRSRLGFNEFSL 60 Query: 61 YKEDRIHIPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGN 120 KED + +P + R+F+ + + PVT AHAG Y CRGSHPH TGWSAPSNP+VIMVTG Sbjct: 61 SKEDGMPVPELYNRVFRNTVFIGPVTPAHAGTYRCRGSHPHFLTGWSAPSNPLVIMVTGV 120 Query: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANF 180 HRKPSLLAHPGPLVKS E VILQCWSD+MFEHF LH+EG D RL G++HDGVSKANF Sbjct: 121 HRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLLHREGKFNDTLRLTGELHDGVSKANF 180 Query: 181 SIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESV 240 SIG M LAGTYRCYGSV H+PYQLSAPSDPLDIV+TG KPSLSAQP P V+AGESV Sbjct: 181 SIGRMTQDLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLCGKPSLSAQPRPMVKAGESV 240 Query: 241 TLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHS 300 TLSCSSRSSYD+YHLSREG AHE R PAV KVN TFQA+FPLGPATHGGTYRCFGSFR S Sbjct: 241 TLSCSSRSSYDIYHLSREGEAHELRFPAVPKVNGTFQANFPLGPATHGGTYRCFGSFRDS 300 Query: 301 PYEWSDPSDPLLVSVT 316 PYEWSD SDPLLVSVT Sbjct: 301 PYEWSDLSDPLLVSVT 316 Score = 143 bits (361), Expect = 3e-34 Identities = 92/221 (41%), Positives = 123/221 (55%), Gaps = 11/221 (4%) Query: 119 GNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKA 178 G KP L A P P+V GE V LQC S + F F L SK+ V ++++ V + Sbjct: 24 GGQDKPFLSAWPSPVVSEGEHVALQCRSRLGFNEFSL-----SKEDGMPVPELYNRVFRN 78 Query: 179 NFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGE 238 IGP+ A AGTYRC GS H SAPS+PL I+VTG + KPSL A PGP V++ E Sbjct: 79 TVFIGPVTPAHAGTYRCRGSHPHFLTGWSAPSNPLVIMVTGVHRKPSLLAHPGPLVKSEE 138 Query: 239 SVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATH--GGTYRCFGS 296 +V L C S ++ + L REG ++ + +A+F +G T GTYRC+GS Sbjct: 139 TVILQCWSDVMFEHFLLHREGKFNDTLRLTGELHDGVSKANFSIGRMTQDLAGTYRCYGS 198 Query: 297 FRHSPYEWSDPSDPLLVSVT---GNPS-SSWPSPTEPSSKS 333 HSPY+ S PSDPL + +T G PS S+ P P + +S Sbjct: 199 VPHSPYQLSAPSDPLDIVITGLCGKPSLSAQPRPMVKAGES 239 Score = 59.7 bits (143), Expect = 5e-09 Identities = 37/102 (36%), Positives = 53/102 (51%), Gaps = 9/102 (8%) Query: 28 KPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIH------IPIFHGRIFQESFN 81 KP LSA P +V G VTL C R ++ + L +E H +P +G FQ +F Sbjct: 223 KPSLSAQPRPMVKAGESVTLSCSSRSSYDIYHLSREGEAHELRFPAVPKVNGT-FQANFP 281 Query: 82 MSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRK 123 + P T H G Y C GS SP WS S+P+++ VT + ++ Sbjct: 282 LGPAT--HGGTYRCFGSFRDSPYEWSDLSDPLLVSVTDSMKE 321 >gi|116517309 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4 [Homo sapiens] Length = 304 Score = 482 bits (1241), Expect = e-136 Identities = 231/281 (82%), Positives = 250/281 (88%) Query: 119 GNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKA 178 G HRKPS LA PG LVKS E VILQCWSD+MFEHF LH+EG + L+G+ HDGVSKA Sbjct: 24 GVHRKPSFLALPGHLVKSEETVILQCWSDVMFEHFLLHREGKFNNTLHLIGEHHDGVSKA 83 Query: 179 NFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGE 238 NFSIGPMM LAGTYRCYGSV H+PYQLSAPSDPLD+V+ G YEKPSLSAQPGP VQAGE Sbjct: 84 NFSIGPMMPVLAGTYRCYGSVPHSPYQLSAPSDPLDMVIIGLYEKPSLSAQPGPTVQAGE 143 Query: 239 SVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFR 298 +VTLSCSSRSSYDMYHLSREG AHERRLPAVR +N TFQADFPLGPATHGGTYRCFGSFR Sbjct: 144 NVTLSCSSRSSYDMYHLSREGEAHERRLPAVRSINGTFQADFPLGPATHGGTYRCFGSFR 203 Query: 299 HSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNPRHLHILIGTSVVIILFILLLFF 358 +PYEWS+ SDPLLVSVTGNPS+SWPSPTEPSSK+GNPRHLH+LIGTSVV I F +LLFF Sbjct: 204 DAPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGNPRHLHVLIGTSVVKIPFTILLFF 263 Query: 359 LLHLWCSNKKNAAVMDQEPAGNRTANSEDSDEQDPEEVTYA 399 LLH WCS+KKNAAVMDQEPAGNRT NSEDSDEQD +EV+YA Sbjct: 264 LLHRWCSDKKNAAVMDQEPAGNRTVNSEDSDEQDHQEVSYA 304 Score = 152 bits (385), Expect = 5e-37 Identities = 88/224 (39%), Positives = 126/224 (56%), Gaps = 7/224 (3%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 MSLMV+ MACVG FL+Q A P G KP A P +V V L+C F +F+L Sbjct: 1 MSLMVIIMACVGFFLLQGAWPQEGVHRKPSFLALPGHLVKSEETVILQCWSDVMFEHFLL 60 Query: 61 YKEDRIH-----IPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVI 115 ++E + + I H + + +F++ P+ AG Y C GS PHSP SAPS+P+ + Sbjct: 61 HREGKFNNTLHLIGEHHDGVSKANFSIGPMMPVLAGTYRCYGSVPHSPYQLSAPSDPLDM 120 Query: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGV 175 ++ G + KPSL A PGP V++GE V L C S ++ + L +EG + + + +G Sbjct: 121 VIIGLYEKPSLSAQPGPTVQAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAVRSINGT 180 Query: 176 SKANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTG 219 +A+F +GP GTYRC+GS PY+ S SDPL + VTG Sbjct: 181 FQADFPLGP--ATHGGTYRCFGSFRDAPYEWSNSSDPLLVSVTG 222 Score = 63.5 bits (153), Expect = 4e-10 Identities = 38/103 (36%), Positives = 52/103 (50%), Gaps = 7/103 (6%) Query: 23 MGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIH---IPIFHG--RIFQ 77 +G +KP LSA P V G +VTL C R ++ + L +E H +P FQ Sbjct: 123 IGLYEKPSLSAQPGPTVQAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAVRSINGTFQ 182 Query: 78 ESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGN 120 F + P T H G Y C GS +P WS S+P+++ VTGN Sbjct: 183 ADFPLGPAT--HGGTYRCFGSFRDAPYEWSNSSDPLLVSVTGN 223 >gi|7657277 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 precursor [Homo sapiens] Length = 304 Score = 482 bits (1240), Expect = e-136 Identities = 238/319 (74%), Positives = 262/319 (82%), Gaps = 16/319 (5%) Query: 81 NMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGERV 140 +++ V+ A G + +G+ PH G HRKPSLLAHPG LVKS E V Sbjct: 2 SLTVVSMACVGFFLLQGAWPHE----------------GVHRKPSLLAHPGRLVKSEETV 45 Query: 141 ILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYGSVT 200 ILQCWSD+MFEHF LH+EG+ D RL+G+ HDGVSKANFSI M LAGTYRCYGSVT Sbjct: 46 ILQCWSDVMFEHFLLHREGMFNDTLRLIGEHHDGVSKANFSISRMKQDLAGTYRCYGSVT 105 Query: 201 HTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGG 260 H+PYQLSAPSDPLDIV+ G YEKPSLSAQPGP V AGE+VTLSCSSRSSYDMYHLSREG Sbjct: 106 HSPYQLSAPSDPLDIVIIGLYEKPSLSAQPGPTVLAGENVTLSCSSRSSYDMYHLSREGE 165 Query: 261 AHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPS 320 AHERRLPA KVN TFQA+FPLGPATHGGTYRCFGSFR SPYEWS SDPLLVSVTGNPS Sbjct: 166 AHERRLPAGTKVNGTFQANFPLGPATHGGTYRCFGSFRDSPYEWSKSSDPLLVSVTGNPS 225 Query: 321 SSWPSPTEPSSKSGNPRHLHILIGTSVVIILFILLLFFLLHLWCSNKKNAAVMDQEPAGN 380 +SWPSPTEPSS++GNPRHLH+LIGTSVV I F +LLFFLLH WCS+KKNAAVMDQEPAGN Sbjct: 226 NSWPSPTEPSSETGNPRHLHVLIGTSVVKIPFTILLFFLLHRWCSDKKNAAVMDQEPAGN 285 Query: 381 RTANSEDSDEQDPEEVTYA 399 RT NSEDSDEQD +EV+YA Sbjct: 286 RTVNSEDSDEQDHQEVSYA 304 Score = 157 bits (396), Expect = 2e-38 Identities = 98/244 (40%), Positives = 135/244 (55%), Gaps = 11/244 (4%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 MSL VVSMACVG FL+Q A PH G KP L A P +V V L+C F +F+L Sbjct: 1 MSLTVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60 Query: 61 YKEDRIH-----IPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVI 115 ++E + I H + + +F++S + AG Y C GS HSP SAPS+P+ I Sbjct: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMKQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120 Query: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGV 175 ++ G + KPSL A PGP V +GE V L C S ++ + L +EG + + G +G Sbjct: 121 VIIGLYEKPSLSAQPGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGTKVNGT 180 Query: 176 SKANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQ 235 +ANF +GP GTYRC+GS +PY+ S SDPL + VTG PS ++ P P Sbjct: 181 FQANFPLGP--ATHGGTYRCFGSFRDSPYEWSKSSDPLLVSVTG---NPS-NSWPSPTEP 234 Query: 236 AGES 239 + E+ Sbjct: 235 SSET 238 >gi|134304835 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5 [Homo sapiens] Length = 304 Score = 471 bits (1211), Expect = e-133 Identities = 229/281 (81%), Positives = 244/281 (86%) Query: 119 GNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKA 178 G RKPSLLAHPGPLVKS E VILQCWSD+MFEHF LH+EG RL+G+ DGVSK Sbjct: 24 GFRRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLLHREGTFNHTLRLIGEHIDGVSKG 83 Query: 179 NFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGE 238 NFSIG M LAGTYRCYGSVTH+PYQLSAPSDPLDIV+TG YEKPSLSAQPGP V AGE Sbjct: 84 NFSIGRMTQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGE 143 Query: 239 SVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFR 298 SVTLSCSSRSSYDMYHLSREG AHERRLPA KVNRTFQADFPL PATHGGTYRCFGSFR Sbjct: 144 SVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNRTFQADFPLDPATHGGTYRCFGSFR 203 Query: 299 HSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNPRHLHILIGTSVVIILFILLLFF 358 SPYEWS SDPLLVSVTGN S+SWPSPTEPSS++GNPRHLH+LIGTSVV + F +LLFF Sbjct: 204 DSPYEWSKSSDPLLVSVTGNSSNSWPSPTEPSSETGNPRHLHVLIGTSVVKLPFTILLFF 263 Query: 359 LLHLWCSNKKNAAVMDQEPAGNRTANSEDSDEQDPEEVTYA 399 LLH WCSNKKNA+VMDQ PAGNRT N EDSDEQD +EV+YA Sbjct: 264 LLHRWCSNKKNASVMDQGPAGNRTVNREDSDEQDHQEVSYA 304 Score = 147 bits (371), Expect = 2e-35 Identities = 93/244 (38%), Positives = 133/244 (54%), Gaps = 11/244 (4%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 MSLMV+SMACV FL+Q A PH G + KP L A P +V V L+C F +F+L Sbjct: 1 MSLMVISMACVAFFLLQGAWPHEGFRRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLL 60 Query: 61 YKEDRIH-----IPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVI 115 ++E + I + + +F++ +T AG Y C GS HSP SAPS+P+ I Sbjct: 61 HREGTFNHTLRLIGEHIDGVSKGNFSIGRMTQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120 Query: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGV 175 ++TG + KPSL A PGP V +GE V L C S ++ + L +EG + + G + Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNRT 180 Query: 176 SKANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQ 235 +A+F + P GTYRC+GS +PY+ S SDPL + VTG S ++ P P Sbjct: 181 FQADFPLDP--ATHGGTYRCFGSFRDSPYEWSKSSDPLLVSVTG----NSSNSWPSPTEP 234 Query: 236 AGES 239 + E+ Sbjct: 235 SSET 238 >gi|6912474 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3 [Homo sapiens] Length = 304 Score = 456 bits (1172), Expect = e-128 Identities = 228/315 (72%), Positives = 248/315 (78%), Gaps = 16/315 (5%) Query: 85 VTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGERVILQC 144 ++ A G + +G+ PH G RKPSLLAHPG LVKS E VILQC Sbjct: 6 ISMACVGFFWLQGAWPHE----------------GFRRKPSLLAHPGRLVKSEETVILQC 49 Query: 145 WSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYGSVTHTPY 204 WSD+MFEHF LH+EG D RL+G+ DGVSKANFSIG M LAGTYRCYGSV H+PY Sbjct: 50 WSDVMFEHFLLHREGTFNDTLRLIGEHIDGVSKANFSIGRMRQDLAGTYRCYGSVPHSPY 109 Query: 205 QLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHER 264 Q SAPSDPLDIV+TG YEKPSLSAQPGP V AGESVTLSCSS SSYDMYHLS EG AHER Sbjct: 110 QFSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSWSSYDMYHLSTEGEAHER 169 Query: 265 RLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSWP 324 R A KVN TFQADFPLGPAT GGTYRCFGSF SPYEWS SDPLLVSVTGNPS+SWP Sbjct: 170 RFSAGPKVNGTFQADFPLGPATQGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWP 229 Query: 325 SPTEPSSKSGNPRHLHILIGTSVVIILFILLLFFLLHLWCSNKKNAAVMDQEPAGNRTAN 384 SPTEPSSK+GNPRHLH+LIGTSVV + F +LLFFLLH WCS+KKNA+VMDQ PAGNRT N Sbjct: 230 SPTEPSSKTGNPRHLHVLIGTSVVKLPFTILLFFLLHRWCSDKKNASVMDQGPAGNRTVN 289 Query: 385 SEDSDEQDPEEVTYA 399 EDSDEQD +EV+YA Sbjct: 290 REDSDEQDHQEVSYA 304 Score = 153 bits (387), Expect = 3e-37 Identities = 92/224 (41%), Positives = 129/224 (57%), Gaps = 7/224 (3%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 MSLMV+SMACVG F +Q A PH G + KP L A P +V V L+C F +F+L Sbjct: 1 MSLMVISMACVGFFWLQGAWPHEGFRRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60 Query: 61 YKE----DRIHIPIFH-GRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVI 115 ++E D + + H + + +F++ + AG Y C GS PHSP +SAPS+P+ I Sbjct: 61 HREGTFNDTLRLIGEHIDGVSKANFSIGRMRQDLAGTYRCYGSVPHSPYQFSAPSDPLDI 120 Query: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGV 175 ++TG + KPSL A PGP V +GE V L C S ++ + L EG + + G +G Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSWSSYDMYHLSTEGEAHERRFSAGPKVNGT 180 Query: 176 SKANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTG 219 +A+F +GP GTYRC+GS +PY+ S SDPL + VTG Sbjct: 181 FQADFPLGP--ATQGGTYRCFGSFHDSPYEWSKSSDPLLVSVTG 222 >gi|11968154 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A [Homo sapiens] Length = 375 Score = 430 bits (1106), Expect = e-120 Identities = 223/321 (69%), Positives = 248/321 (77%), Gaps = 7/321 (2%) Query: 119 GNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKE-GISKDPSRLVGQIHDGVSK 177 G KP L A P +V G V L C S + F F L+KE G+ V ++++ + Sbjct: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVP------VPELYNKIFW 77 Query: 178 ANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAG 237 + +GP+ A AGTYRC GS +P + SAPS+PL IVVTG + KPSLSAQPGP V+ G Sbjct: 78 KSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLFGKPSLSAQPGPTVRTG 137 Query: 238 ESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSF 297 E+VTLSCSSRSS+DMYHLSREG AHE RLPAV VN TFQADFPLGPATHGGTY CFGS Sbjct: 138 ENVTLSCSSRSSFDMYHLSREGRAHEPRLPAVPSVNGTFQADFPLGPATHGGTYTCFGSL 197 Query: 298 RHSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNPRHLHILIGTSVVIILFILLLF 357 SPYEWSDPSDPLLVSVTGN SSS SPTEPSSK+G RHLHILIGTSV IILFI+L F Sbjct: 198 HDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLHILIGTSVAIILFIILFF 257 Query: 358 FLLHLWCSNKKNAAVMDQEPAGNRTANSEDSDEQDPEEVTYAQLDHCVFTQRKITRPSQR 417 FLLH CSNKKNAAVMDQEPAG+RT N EDSD+QDP+EVTYAQLDHCVFTQ KIT PSQR Sbjct: 258 FLLHCCCSNKKNAAVMDQEPAGDRTVNREDSDDQDPQEVTYAQLDHCVFTQTKITSPSQR 317 Query: 418 PKTPPTDTILYTELPNAKPRS 438 PKTPPTDT +Y ELPNAKPRS Sbjct: 318 PKTPPTDTTMYMELPNAKPRS 338 Score = 242 bits (617), Expect = 6e-64 Identities = 127/234 (54%), Positives = 153/234 (65%), Gaps = 3/234 (1%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 MSLMV+SMACVG FL+Q A H GGQDKP LSAWPSAVVPRGGHVTL C R F F L Sbjct: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 Query: 61 YKEDRIHIPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGN 120 YKED + +P + +IF +S M PVT AHAG Y CRGSHP SP WSAPSNP+VI+VTG Sbjct: 61 YKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGL 120 Query: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANF 180 KPSL A PGP V++GE V L C S F+ + L +EG + +P +G +A+F Sbjct: 121 FGKPSLSAQPGPTVRTGENVTLSCSSRSSFDMYHLSREGRAHEPRLPAVPSVNGTFQADF 180 Query: 181 SIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLS-AQPGPK 233 +GP GTY C+GS+ +PY+ S PSDPL + VTG S S +P K Sbjct: 181 PLGP--ATHGGTYTCFGSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSK 232 >gi|66267727 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5B precursor [Homo sapiens] Length = 375 Score = 419 bits (1078), Expect = e-117 Identities = 218/321 (67%), Positives = 244/321 (76%), Gaps = 7/321 (2%) Query: 119 GNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKE-GISKDPSRLVGQIHDGVSK 177 G KP L A P +V G V L C S + F F L+KE G+ V ++++ + Sbjct: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVP------VPELYNKIFW 77 Query: 178 ANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAG 237 + +GP+ A AGTYRC GS +P + SAPS+PL IVVTG + KPSLSAQPGP V+ G Sbjct: 78 KSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLFGKPSLSAQPGPTVRTG 137 Query: 238 ESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSF 297 E+V LSCSSRSS+DMYHLSREG AHE RLPAV V+ TFQADFPLGPATHGGTY CF S Sbjct: 138 ENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADFPLGPATHGGTYTCFSSL 197 Query: 298 RHSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNPRHLHILIGTSVVIILFILLLF 357 SPYEWSDPSDPLLVSVTGN SSS SPTEPSSK+G RHLHILIGTSV IILFI+L F Sbjct: 198 HDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLHILIGTSVAIILFIILFF 257 Query: 358 FLLHLWCSNKKNAAVMDQEPAGNRTANSEDSDEQDPEEVTYAQLDHCVFTQRKITRPSQR 417 FLLH CSNKKNAAVMDQ PAG+RT N EDSD+QDP+EVTYAQLDHCVFTQ KIT PSQR Sbjct: 258 FLLHCCCSNKKNAAVMDQGPAGDRTVNREDSDDQDPQEVTYAQLDHCVFTQTKITSPSQR 317 Query: 418 PKTPPTDTILYTELPNAKPRS 438 PK PPTDT +Y ELPNAKPRS Sbjct: 318 PKAPPTDTTMYMELPNAKPRS 338 Score = 241 bits (616), Expect = 7e-64 Identities = 127/234 (54%), Positives = 152/234 (64%), Gaps = 3/234 (1%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 MSLMV+SMACVG FL+Q A H GGQDKP LSAWPSAVVPRGGHVTL C R F F L Sbjct: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 Query: 61 YKEDRIHIPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGN 120 YKED + +P + +IF +S M PVT AHAG Y CRGSHP SP WSAPSNP+VI+VTG Sbjct: 61 YKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGL 120 Query: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANF 180 KPSL A PGP V++GE V L C S F+ + L +EG + +P DG +A+F Sbjct: 121 FGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADF 180 Query: 181 SIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLS-AQPGPK 233 +GP GTY C+ S+ +PY+ S PSDPL + VTG S S +P K Sbjct: 181 PLGP--ATHGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSK 232 >gi|124107606 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 isoform a [Homo sapiens] Length = 377 Score = 409 bits (1050), Expect = e-114 Identities = 209/321 (65%), Positives = 243/321 (75%), Gaps = 7/321 (2%) Query: 119 GNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHK-EGISKDPSRLVGQIHDGVSK 177 G KP A P +V G V L+C F F L+K +G+ V ++++ + Sbjct: 26 GGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTLYKKDGVP------VPELYNRIFW 79 Query: 178 ANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAG 237 +F I P+ A AGTYRC G H+P + SAPS+PL I+VTG YEKPSL+A+PGP V+AG Sbjct: 80 NSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGLYEKPSLTARPGPTVRAG 139 Query: 238 ESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSF 297 E+VTLSCSS+SS+D+YHLSREG AHE RLPAV +N TFQADFPLGPATHG TYRCFGSF Sbjct: 140 ENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADFPLGPATHGETYRCFGSF 199 Query: 298 RHSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNPRHLHILIGTSVVIILFILLLF 357 SPYEWSDPSDPL VSVTGNPSSSWPSPTEPS K+G RHLH +I SV IILF +L F Sbjct: 200 HGSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKTGIARHLHAVIRYSVAIILFTILPF 259 Query: 358 FLLHLWCSNKKNAAVMDQEPAGNRTANSEDSDEQDPEEVTYAQLDHCVFTQRKITRPSQR 417 FLLH WCS KKNAAVM+QEPAG+RT N EDSDEQDP+EVTYAQLDHC+FTQRKIT PSQR Sbjct: 260 FLLHRWCSKKKNAAVMNQEPAGHRTVNREDSDEQDPQEVTYAQLDHCIFTQRKITGPSQR 319 Query: 418 PKTPPTDTILYTELPNAKPRS 438 K P TDT + ELPNA+PR+ Sbjct: 320 SKRPSTDTSVCIELPNAEPRA 340 Score = 246 bits (629), Expect = 2e-65 Identities = 127/232 (54%), Positives = 155/232 (66%), Gaps = 6/232 (2%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 MS V+ +AC+G FL Q H+GGQDKPF SAWPSAVVP+GGHVTLRCHYR FN F L Sbjct: 3 MSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTL 62 Query: 61 YKEDRIHIPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGN 120 YK+D + +P + RIF SF +SPVT AHAG Y CRG HPHSPT WSAPSNP+VIMVTG Sbjct: 63 YKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGL 122 Query: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANF 180 + KPSL A PGP V++GE V L C S F+ + L +EG + + +G +A+F Sbjct: 123 YEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADF 182 Query: 181 SIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGP 232 +GP TYRC+GS +PY+ S PSDPL + VTG PS S+ P P Sbjct: 183 PLGP--ATHGETYRCFGSFHGSPYEWSDPSDPLPVSVTG---NPS-SSWPSP 228 >gi|124107610 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 isoform c [Homo sapiens] Length = 342 Score = 345 bits (884), Expect = 6e-95 Identities = 185/321 (57%), Positives = 218/321 (67%), Gaps = 42/321 (13%) Query: 119 GNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHK-EGISKDPSRLVGQIHDGVSK 177 G KP A P +V G V L+C F F L+K +G+ V ++++ + Sbjct: 26 GGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTLYKKDGVP------VPELYNRIFW 79 Query: 178 ANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAG 237 +F I P+ A AGTYRC G H+P + SAPS+PL I+VTG YEKPSL+A+PGP V+AG Sbjct: 80 NSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGLYEKPSLTARPGPTVRAG 139 Query: 238 ESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSF 297 E+VTLSCSS+SS+D+YHLSREG AHE RLPAV +N TFQADFPLGPATHG TYRCFGSF Sbjct: 140 ENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADFPLGPATHGETYRCFGSF 199 Query: 298 RHSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNPRHLHILIGTSVVIILFILLLF 357 SPYEWSDPSDPL VSVTGNPSSSWPSPTEPS K+ Sbjct: 200 HGSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKT------------------------ 235 Query: 358 FLLHLWCSNKKNAAVMDQEPAGNRTANSEDSDEQDPEEVTYAQLDHCVFTQRKITRPSQR 417 +AAVM+QEPAG+RT N EDSDEQDP+EVTYAQLDHC+FTQRKIT PSQR Sbjct: 236 -----------DAAVMNQEPAGHRTVNREDSDEQDPQEVTYAQLDHCIFTQRKITGPSQR 284 Query: 418 PKTPPTDTILYTELPNAKPRS 438 K P TDT + ELPNA+PR+ Sbjct: 285 SKRPSTDTSVCIELPNAEPRA 305 Score = 246 bits (629), Expect = 2e-65 Identities = 127/232 (54%), Positives = 155/232 (66%), Gaps = 6/232 (2%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 MS V+ +AC+G FL Q H+GGQDKPF SAWPSAVVP+GGHVTLRCHYR FN F L Sbjct: 3 MSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTL 62 Query: 61 YKEDRIHIPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGN 120 YK+D + +P + RIF SF +SPVT AHAG Y CRG HPHSPT WSAPSNP+VIMVTG Sbjct: 63 YKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGL 122 Query: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANF 180 + KPSL A PGP V++GE V L C S F+ + L +EG + + +G +A+F Sbjct: 123 YEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADF 182 Query: 181 SIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGP 232 +GP TYRC+GS +PY+ S PSDPL + VTG PS S+ P P Sbjct: 183 PLGP--ATHGETYRCFGSFHGSPYEWSDPSDPLPVSVTG---NPS-SSWPSP 228 >gi|71143143 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 isoform 1 [Homo sapiens] Length = 243 Score = 305 bits (781), Expect = 5e-83 Identities = 151/220 (68%), Positives = 172/220 (78%), Gaps = 2/220 (0%) Query: 219 GPYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQA 278 G + KPSL A PGP V++ E+V L C S + + L REG + + +A Sbjct: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 Query: 279 DFPLGPATH--GGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNP 336 +F +GP GTYRC+GS HSPY+ S PSDPLLVSVTGNPS+SWPSPTEPSS++GNP Sbjct: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNP 143 Query: 337 RHLHILIGTSVVIILFILLLFFLLHLWCSNKKNAAVMDQEPAGNRTANSEDSDEQDPEEV 396 RHLH+LIGTSVVIILFILLLFFLLH WC NKKNA VMDQEPAGNRT N EDSDEQDP+EV Sbjct: 144 RHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEV 203 Query: 397 TYAQLDHCVFTQRKITRPSQRPKTPPTDTILYTELPNAKP 436 TYAQL+HCVFTQRKITRPSQRPKTPPTD I+YTELPNA+P Sbjct: 204 TYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAEP 243 Score = 168 bits (426), Expect = 8e-42 Identities = 84/121 (69%), Positives = 95/121 (78%), Gaps = 4/121 (3%) Query: 119 GNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKA 178 G HRKPSLLAHPGPLVKS E VILQCWSD+ F+HF LH+EG KD L+G+ HDGVSKA Sbjct: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 Query: 179 NFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGE 238 NFSIGPMM LAGTYRCYGSVTH+PYQLSAPSDPL + VTG PS ++ P P + E Sbjct: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTG---NPS-NSWPSPTEPSSE 139 Query: 239 S 239 + Sbjct: 140 T 140 Score = 96.7 bits (239), Expect = 4e-20 Identities = 79/236 (33%), Positives = 112/236 (47%), Gaps = 21/236 (8%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 MSLMVVSM CVG FL+Q A PH G KP L A P +V V L+C RF +F+L Sbjct: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 Query: 61 YKE----DRIH-IPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVI 115 ++E D +H I H + + +F++ P+ AG Y C GS HSP SAPS+P+++ Sbjct: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120 Query: 116 MVTGN--------HRKPSLLAHPGPL-VKSGERVILQCWSDIMFEHFFLHKEGISKDPSR 166 VTGN S +P L V G V++ + ++F F LH+ +K + Sbjct: 121 SVTGNPSNSWPSPTEPSSETGNPRHLHVLIGTSVVIILFILLLF--FLLHRWCCNKKNAV 178 Query: 167 LVGQIHDGVSKANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSD-----PLDIVV 217 ++ Q G N TY T +++ PS P DI+V Sbjct: 179 VMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDIIV 234 >gi|124107604 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 isoform b [Homo sapiens] Length = 273 Score = 298 bits (762), Expect = 9e-81 Identities = 155/251 (61%), Positives = 182/251 (72%), Gaps = 7/251 (2%) Query: 119 GNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHK-EGISKDPSRLVGQIHDGVSK 177 G KP A P +V G V L+C F F L+K +G+ V ++++ + Sbjct: 26 GGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTLYKKDGVP------VPELYNRIFW 79 Query: 178 ANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAG 237 +F I P+ A AGTYRC G H+P + SAPS+PL I+VTG YEKPSL+A+PGP V+AG Sbjct: 80 NSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGLYEKPSLTARPGPTVRAG 139 Query: 238 ESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSF 297 E+VTLSCSS+SS+D+YHLSREG AHE RLPAV +N TFQADFPLGPATHG TYRCFGSF Sbjct: 140 ENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADFPLGPATHGETYRCFGSF 199 Query: 298 RHSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNPRHLHILIGTSVVIILFILLLF 357 SPYEWSDPSDPL VSVTGNPSSSWPSPTEPS K+G RHLH +I SV IILF +L F Sbjct: 200 HGSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKTGIARHLHAVIRYSVAIILFTILPF 259 Query: 358 FLLHLWCSNKK 368 FLLH WCS KK Sbjct: 260 FLLHRWCSKKK 270 Score = 246 bits (629), Expect = 2e-65 Identities = 127/232 (54%), Positives = 155/232 (66%), Gaps = 6/232 (2%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 MS V+ +AC+G FL Q H+GGQDKPF SAWPSAVVP+GGHVTLRCHYR FN F L Sbjct: 3 MSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTL 62 Query: 61 YKEDRIHIPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGN 120 YK+D + +P + RIF SF +SPVT AHAG Y CRG HPHSPT WSAPSNP+VIMVTG Sbjct: 63 YKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGL 122 Query: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANF 180 + KPSL A PGP V++GE V L C S F+ + L +EG + + +G +A+F Sbjct: 123 YEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADF 182 Query: 181 SIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGP 232 +GP TYRC+GS +PY+ S PSDPL + VTG PS S+ P P Sbjct: 183 PLGP--ATHGETYRCFGSFHGSPYEWSDPSDPLPVSVTG---NPS-SSWPSP 228 >gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B, member 3 isoform 2 [Homo sapiens] Length = 631 Score = 269 bits (688), Expect = 3e-72 Identities = 165/444 (37%), Positives = 248/444 (55%), Gaps = 26/444 (5%) Query: 24 GGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHIPI------FHGRIFQ 77 G KP LSA PS VV GG++TLRC + +++F+L KE +P H R FQ Sbjct: 119 GAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQ 178 Query: 78 ESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSG 137 F + PVT +H +TC + ++P WS PS+P+ I+ +G RKPSLL GP++ G Sbjct: 179 ALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPG 238 Query: 138 ERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYG 197 + + LQC SD+ + F L+KEG R Q G+S+ANF++GP+ + G YRCYG Sbjct: 239 QSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYG 298 Query: 198 SVTHTPYQLSAPSDPLDIVVTGP-YEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLS 256 + + + SAPSDPL+I++ G Y+ SLSAQPGP V +GE+VTL C S +D + L+ Sbjct: 299 A-HNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLT 357 Query: 257 REGGAH-ERRLPAVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEWSDPSDPLLV 313 +EG AH RL ++ ++ +QA+FP+ P T H GTYRC+GS+ +P+ S PS+PL + Sbjct: 358 KEGAAHPPLRLRSMYGAHK-YQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPLEL 416 Query: 314 SVTGNPSSSWPSPTEPSSKSGNPRHLHILIGTSVVIILFILLLFFLLHLWCSNKKNAAVM 373 V+G+ S PT P S G R+L +LIG SV +L + LL FLL + K+ Sbjct: 417 VVSGHSGGSSLPPTGPPSTPGLGRYLEVLIGVSVAFVLLLFLLLFLLLRRQRHSKHRTSD 476 Query: 374 DQEPAGNRTANSEDSDEQD-------------PEEVTYAQLDHCVFTQRKITRPSQRPKT 420 ++ R A + +++ +D EE YA + ++ ++ SQ P Sbjct: 477 QRKTDFQRPAGAAETEPKDRGLLRRSSPAADVQEENLYAAVKD-TQSEDRVELDSQSPHD 535 Query: 421 PPTDTILYTELPNAKPRSKVVSCP 444 + Y + ++ PR ++ S P Sbjct: 536 EDPQAVTYAPVKHSSPRREMASPP 559 Score = 186 bits (472), Expect = 4e-47 Identities = 121/345 (35%), Positives = 178/345 (51%), Gaps = 17/345 (4%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 M+ + ++ C+GL L R G KP L A P +V+ G VT+ C + L Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRL 60 Query: 61 YKEDRIHIPIFHGRIFQES----FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIM 116 +KE P+ + F++ +T HAG Y C H +S GWS PS+P+ ++ Sbjct: 61 HKEGSPE-PLDRNNPLEPKNKARFSIPSMTEHHAGRYRC---HYYSSAGWSEPSDPLEMV 116 Query: 117 VTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVG-QIHDGV 175 +TG + KP+L A P P+V SG + L+C S + HF L KEG + P L Q+H Sbjct: 117 MTGAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRG 176 Query: 176 SKANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQ 235 +A F +GP+ + + CY T+TP+ S PSDPL+I+ +G KPSL GP + Sbjct: 177 FQALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLA 236 Query: 236 AGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPA--THGGTYRC 293 G+S+TL C S Y+ + L +EG + P + QA+F LGP ++GG YRC Sbjct: 237 PGQSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRC 296 Query: 294 FGSFRHSPYEWSDPSDPLLVSVTGN-----PSSSWPSPTEPSSKS 333 +G+ S EWS PSDPL + + G S+ P PT S ++ Sbjct: 297 YGAHNLSS-EWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGEN 340 Score = 30.8 bits (68), Expect = 2.6 Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 2/59 (3%) Query: 374 DQEPAGNRTANSEDSDEQDPEEVTYAQLDHCVFTQRKITR-PSQRPKTPPTDTILYTEL 431 D++ +R ++E + + ++VTYAQL H + +RK T P + PP + +Y L Sbjct: 571 DRQVEEDRQMDTEAAASEASQDVTYAQL-HSLTLRRKATEPPPSQEGEPPAEPSIYATL 628 >gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B, member 3 isoform 1 [Homo sapiens] Length = 632 Score = 269 bits (687), Expect = 4e-72 Identities = 165/444 (37%), Positives = 244/444 (54%), Gaps = 25/444 (5%) Query: 24 GGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHIPI------FHGRIFQ 77 G KP LSA PS VV GG++TLRC + +++F+L KE +P H R FQ Sbjct: 119 GAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQ 178 Query: 78 ESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSG 137 F + PVT +H +TC + ++P WS PS+P+ I+ +G RKPSLL GP++ G Sbjct: 179 ALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPG 238 Query: 138 ERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYG 197 + + LQC SD+ + F L+KEG R Q G+S+ANF++GP+ + G YRCYG Sbjct: 239 QSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYG 298 Query: 198 SVTHTPYQLSAPSDPLDIVVTGP-YEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLS 256 + + + SAPSDPL+I++ G Y+ SLSAQPGP V +GE+VTL C S +D + L+ Sbjct: 299 A-HNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLT 357 Query: 257 REGGAH-ERRLPAVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEWSDPSDPLLV 313 +EG AH RL ++ ++ +QA+FP+ P T H GTYRC+GS+ +P+ S PS+PL + Sbjct: 358 KEGAAHPPLRLRSMYGAHK-YQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPLEL 416 Query: 314 SVTGNPSSSWPSPTEPSSKSGNPRHLHILIGTSVVIILFILLLFFLLHLWCSNKKNAAVM 373 V+G+ S PT P S G R+L +LIG SV +L + LL FLL + K+ Sbjct: 417 VVSGHSGGSSLPPTGPPSTPGLGRYLEVLIGVSVAFVLLLFLLLFLLLRRQRHSKHRTSD 476 Query: 374 DQEPAGNRTANSEDSDEQD-------------PEEVTYAQLDHCVFTQRKITRPSQRPKT 420 ++ R A + +++ +D EE YA + R Q P Sbjct: 477 QRKTDFQRPAGAAETEPKDRGLLRRSSPAADVQEENLYAAVKDTQSEDRVELDSQQSPHD 536 Query: 421 PPTDTILYTELPNAKPRSKVVSCP 444 + Y + ++ PR ++ S P Sbjct: 537 EDPQAVTYAPVKHSSPRREMASPP 560 Score = 186 bits (472), Expect = 4e-47 Identities = 121/345 (35%), Positives = 178/345 (51%), Gaps = 17/345 (4%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 M+ + ++ C+GL L R G KP L A P +V+ G VT+ C + L Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRL 60 Query: 61 YKEDRIHIPIFHGRIFQES----FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIM 116 +KE P+ + F++ +T HAG Y C H +S GWS PS+P+ ++ Sbjct: 61 HKEGSPE-PLDRNNPLEPKNKARFSIPSMTEHHAGRYRC---HYYSSAGWSEPSDPLEMV 116 Query: 117 VTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVG-QIHDGV 175 +TG + KP+L A P P+V SG + L+C S + HF L KEG + P L Q+H Sbjct: 117 MTGAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRG 176 Query: 176 SKANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQ 235 +A F +GP+ + + CY T+TP+ S PSDPL+I+ +G KPSL GP + Sbjct: 177 FQALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLA 236 Query: 236 AGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPA--THGGTYRC 293 G+S+TL C S Y+ + L +EG + P + QA+F LGP ++GG YRC Sbjct: 237 PGQSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRC 296 Query: 294 FGSFRHSPYEWSDPSDPLLVSVTGN-----PSSSWPSPTEPSSKS 333 +G+ S EWS PSDPL + + G S+ P PT S ++ Sbjct: 297 YGAHNLSS-EWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGEN 340 Score = 30.8 bits (68), Expect = 2.6 Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 2/59 (3%) Query: 374 DQEPAGNRTANSEDSDEQDPEEVTYAQLDHCVFTQRKITR-PSQRPKTPPTDTILYTEL 431 D++ +R ++E + + ++VTYAQL H + +RK T P + PP + +Y L Sbjct: 572 DRQVEEDRQMDTEAAASEASQDVTYAQL-HSLTLRRKATEPPPSQEGEPPAEPSIYATL 629 >gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B, member 2 isoform 2 [Homo sapiens] Length = 597 Score = 248 bits (632), Expect = 1e-65 Identities = 171/480 (35%), Positives = 247/480 (51%), Gaps = 76/480 (15%) Query: 24 GGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHIPIF-----HGRIFQE 78 G KP LSA PS VV GG VTL+C + F F+L KE P H R Sbjct: 119 GAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSR 178 Query: 79 S-FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSG 137 + F++ PV+ ++ C G +SP WS+PS+ + ++V G +KPSL PGP+V G Sbjct: 179 AIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPG 238 Query: 138 ERVILQCWSDIMFEHFFLHKEGISKDPSRLVG-QIHDGVSKANFSIGPMMLALAGTYRCY 196 E + LQC SD+ ++ F L+KEG +D +L G Q G+S+ANF++GP+ + G YRCY Sbjct: 239 ESLTLQCVSDVGYDRFVLYKEG-ERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCY 297 Query: 197 GSVTHTPYQLSAPSDPLDIVVTGPYE-KPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHL 255 G+ + + SAPSDPLDI++TG P +S QPGP V +GE+VTL C S + + L Sbjct: 298 GA-HNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLL 356 Query: 256 SREGGAHER-RLPAVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEWSDPSDPLL 312 ++ G A RL ++ + + +QA+FP+ P T H GTYRC+GS PY S PS+PL Sbjct: 357 TKAGAADAPLRLRSIHEYPK-YQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLE 415 Query: 313 VSVTGNPSSSWPSPTEPSS----------------KSGNPRHLHILIG--TSVVIILFIL 354 + V+G S P PT P S +SG RHL ++IG +VV++L +L Sbjct: 416 LVVSGPSMGSSPPPTGPISTPGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVVLLLLLL 475 Query: 355 LLFFLL-------HLWCSNKKN-----------------------------------AAV 372 LL FL+ W S ++ AAV Sbjct: 476 LLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGLQWRSSPAADAQEENLYAAV 535 Query: 373 MDQEPAGNRTANSEDSDEQDPEEVTYAQLDHCVFTQRKITR-PSQRPKTPPTDTILYTEL 431 D +P ++ + + P++VTYAQL H + +RK T P + + PP + +Y L Sbjct: 536 KDTQPEDGVEMDTRAAASEAPQDVTYAQL-HSLTLRRKATEPPPSQEREPPAEPSIYATL 594 Score = 208 bits (529), Expect = 9e-54 Identities = 135/344 (39%), Positives = 187/344 (54%), Gaps = 15/344 (4%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 M+ +V + C+GL L R G KP L A P +V+ +G VTL C + L Sbjct: 1 MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRL 60 Query: 61 YKEDRIHIPIFHGR---IFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMV 117 Y+E + I R + F++ +T H G Y C+ +S WS S+P+V+++ Sbjct: 61 YREKKSASWITRIRPELVKNGQFHIPSITWEHTGRYGCQY---YSRARWSELSDPLVLVM 117 Query: 118 TGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHD-GVS 176 TG + KP+L A P P+V SG RV LQC S + F F L KEG + P L Q H G S Sbjct: 118 TGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSS 177 Query: 177 KANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQA 236 +A FS+GP+ ++RCYG ++PY S+PSD L+++V G +KPSLS QPGP V Sbjct: 178 RAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAP 237 Query: 237 GESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPA--THGGTYRCF 294 GES+TL C S YD + L +EG R+LP + QA+F LGP ++GG YRC+ Sbjct: 238 GESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCY 297 Query: 295 GSFRHSPYEWSDPSDPLLVSVTGNPS-----SSWPSPTEPSSKS 333 G+ S E S PSDPL + +TG S P PT S ++ Sbjct: 298 GAHNLSS-ECSAPSDPLDILITGQIRGTPFISVQPGPTVASGEN 340 >gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B, member 2 isoform 1 [Homo sapiens] Length = 598 Score = 247 bits (631), Expect = 1e-65 Identities = 171/481 (35%), Positives = 247/481 (51%), Gaps = 77/481 (16%) Query: 24 GGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHIPIF-----HGRIFQE 78 G KP LSA PS VV GG VTL+C + F F+L KE P H R Sbjct: 119 GAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSR 178 Query: 79 S-FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSG 137 + F++ PV+ ++ C G +SP WS+PS+ + ++V G +KPSL PGP+V G Sbjct: 179 AIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPG 238 Query: 138 ERVILQCWSDIMFEHFFLHKEGISKDPSRLVG-QIHDGVSKANFSIGPMMLALAGTYRCY 196 E + LQC SD+ ++ F L+KEG +D +L G Q G+S+ANF++GP+ + G YRCY Sbjct: 239 ESLTLQCVSDVGYDRFVLYKEG-ERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCY 297 Query: 197 GSVTHTPYQLSAPSDPLDIVVTGPYE-KPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHL 255 G+ + + SAPSDPLDI++TG P +S QPGP V +GE+VTL C S + + L Sbjct: 298 GA-HNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLL 356 Query: 256 SREGGAHER-RLPAVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEWSDPSDPLL 312 ++ G A RL ++ + + +QA+FP+ P T H GTYRC+GS PY S PS+PL Sbjct: 357 TKAGAADAPLRLRSIHEYPK-YQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLE 415 Query: 313 VSVTGNPSSSWPSPTEPSS-----------------KSGNPRHLHILIG--TSVVIILFI 353 + V+G S P PT P S +SG RHL ++IG +VV++L + Sbjct: 416 LVVSGPSMGSSPPPTGPISTPAGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVVLLLLL 475 Query: 354 LLLFFLL-------HLWCSNKKN-----------------------------------AA 371 LLL FL+ W S ++ AA Sbjct: 476 LLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGLQWRSSPAADAQEENLYAA 535 Query: 372 VMDQEPAGNRTANSEDSDEQDPEEVTYAQLDHCVFTQRKITR-PSQRPKTPPTDTILYTE 430 V D +P ++ + + P++VTYAQL H + +RK T P + + PP + +Y Sbjct: 536 VKDTQPEDGVEMDTRAAASEAPQDVTYAQL-HSLTLRRKATEPPPSQEREPPAEPSIYAT 594 Query: 431 L 431 L Sbjct: 595 L 595 Score = 208 bits (529), Expect = 9e-54 Identities = 135/344 (39%), Positives = 187/344 (54%), Gaps = 15/344 (4%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 M+ +V + C+GL L R G KP L A P +V+ +G VTL C + L Sbjct: 1 MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRL 60 Query: 61 YKEDRIHIPIFHGR---IFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMV 117 Y+E + I R + F++ +T H G Y C+ +S WS S+P+V+++ Sbjct: 61 YREKKSASWITRIRPELVKNGQFHIPSITWEHTGRYGCQY---YSRARWSELSDPLVLVM 117 Query: 118 TGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHD-GVS 176 TG + KP+L A P P+V SG RV LQC S + F F L KEG + P L Q H G S Sbjct: 118 TGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSS 177 Query: 177 KANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQA 236 +A FS+GP+ ++RCYG ++PY S+PSD L+++V G +KPSLS QPGP V Sbjct: 178 RAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAP 237 Query: 237 GESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPA--THGGTYRCF 294 GES+TL C S YD + L +EG R+LP + QA+F LGP ++GG YRC+ Sbjct: 238 GESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCY 297 Query: 295 GSFRHSPYEWSDPSDPLLVSVTGNPS-----SSWPSPTEPSSKS 333 G+ S E S PSDPL + +TG S P PT S ++ Sbjct: 298 GAHNLSS-ECSAPSDPLDILITGQIRGTPFISVQPGPTVASGEN 340 >gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B, member 1 isoform 4 [Homo sapiens] Length = 651 Score = 239 bits (610), Expect = 4e-63 Identities = 168/464 (36%), Positives = 236/464 (50%), Gaps = 47/464 (10%) Query: 24 GGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHIPIF-----HGRIFQE 78 G KP LSA PS VV GG+V L+C + F+ F L KE P H R Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179 Query: 79 S-FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSG 137 + F++ PV+ + Y C +SP WS PS+ + ++V G +KPSL PGP+V Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239 Query: 138 ERVILQCWSDIMFEHFFLHKEGISKDPSRLVG-QIHDGVSKANFSIGPMMLALAGTYRCY 196 E + LQC SD + F L+K+G +D +L G Q G+S+ANF++GP+ + G YRCY Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDG-ERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCY 298 Query: 197 GSVTHTPYQLSAPSDPLDIVVTGP-YEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHL 255 G+ + + SAPSDPLDI++ G Y++ SLS QPGP V +GE+VTL C S+ + L Sbjct: 299 GA-HNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLL 357 Query: 256 SREGGAHERRLPAVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEWSDPSDPLLV 313 ++EG A + ++ +QA+FP+GP T H GTYRC+GS PY + PSDPL + Sbjct: 358 TKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLEL 417 Query: 314 SV---TGNPSSSWPSPTEPSS-------------KSGNPRHLHILIGTSVVIILFILLLF 357 V +G PSS PT S +SG RHL ++IG V +IL +LLL Sbjct: 418 VVSGPSGGPSSPTTGPTSTSGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVILLLLLLL 477 Query: 358 FLLHL---------WCSNKKNAAVMDQEPAG-------NRTANSEDSDEQD-PEEVTYAQ 400 L + W S ++ A Q PAG +R S D EE YA Sbjct: 478 LLFLILRHRRQGKHWTSTQRKADF--QHPAGAVGPEPTDRGLQWRSSPAADAQEENLYAA 535 Query: 401 LDHCVFTQRKITRPSQRPKTPPTDTILYTELPNAKPRSKVVSCP 444 + H Q P + Y E+ +++PR ++ S P Sbjct: 536 VKHTQPEDGVEMDTRQSPHDEDPQAVTYAEVKHSRPRREMASPP 579 Score = 203 bits (517), Expect = 2e-52 Identities = 132/346 (38%), Positives = 187/346 (54%), Gaps = 18/346 (5%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 M+ ++ + C+GL L R G KP L A P +V+ +G VTLRC + L Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60 Query: 61 YKEDRIHIPIFHGRIFQE-----SFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVI 115 Y+E + + I RI QE F + +T HAG Y C + G S S+P+ + Sbjct: 61 YREKKTALWIT--RIPQELVKKGQFPIPSITWEHAGRYRCY--YGSDTAGRSESSDPLEL 116 Query: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHD-G 174 +VTG + KP+L A P P+V SG VILQC S + F+ F L KEG + P L Q H G Sbjct: 117 VVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARG 176 Query: 175 VSKANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKV 234 S+A FS+GP+ + YRCY +++PY+ S PSD L+++V G +KPSLS QPGP V Sbjct: 177 SSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIV 236 Query: 235 QAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPA--THGGTYR 292 E++TL C S + Y+ + L ++G +L + QA+F LGP ++GG YR Sbjct: 237 APEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYR 296 Query: 293 CFGSFRHSPYEWSDPSDPLLVSVTGN-----PSSSWPSPTEPSSKS 333 C+G+ S EWS PSDPL + + G S P PT S ++ Sbjct: 297 CYGAHNLSS-EWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGEN 341 Score = 145 bits (367), Expect = 6e-35 Identities = 88/221 (39%), Positives = 120/221 (54%), Gaps = 8/221 (3%) Query: 23 MGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHIPIFHGR-----IFQ 77 +G KP LS P +V +TL+C +N F+LYK+ G + Q Sbjct: 220 LGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQ 279 Query: 78 ESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGN-HRKPSLLAHPGPLVKS 136 +F + PV+ ++ G Y C G+H S + WSAPS+P+ I++ G + + SL PGP V S Sbjct: 280 ANFTLGPVSRSYGGQYRCYGAHNLS-SEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVAS 338 Query: 137 GERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCY 196 GE V L C S + F L KEG + DP RL +A F +GP+ A AGTYRCY Sbjct: 339 GENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCY 398 Query: 197 GSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAG 237 GS + PY L+ PSDPL++VV+GP PS S GP +G Sbjct: 399 GSQSSKPYLLTHPSDPLELVVSGPSGGPS-SPTTGPTSTSG 438 Score = 31.6 bits (70), Expect = 1.5 Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 3/58 (5%) Query: 374 DQEPAGNRTANSEDSDEQDPEEVTYAQLDHCVFTQRKITR--PSQRPKTPPTDTILYT 429 D++ +R ++E + + P++VTYAQL H + +R+ T PSQ +P +I T Sbjct: 591 DRQAEEDRQMDTEAAASEAPQDVTYAQL-HSLTLRREATEPPPSQEGPSPAVPSIYAT 647 >gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B, member 1 isoform 2 [Homo sapiens] Length = 652 Score = 239 bits (610), Expect = 4e-63 Identities = 168/465 (36%), Positives = 237/465 (50%), Gaps = 48/465 (10%) Query: 24 GGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHIPIF-----HGRIFQE 78 G KP LSA PS VV GG+V L+C + F+ F L KE P H R Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179 Query: 79 S-FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSG 137 + F++ PV+ + Y C +SP WS PS+ + ++V G +KPSL PGP+V Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239 Query: 138 ERVILQCWSDIMFEHFFLHKEGISKDPSRLVG-QIHDGVSKANFSIGPMMLALAGTYRCY 196 E + LQC SD + F L+K+G +D +L G Q G+S+ANF++GP+ + G YRCY Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDG-ERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCY 298 Query: 197 GSVTHTPYQLSAPSDPLDIVVTGP-YEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHL 255 G+ + + SAPSDPLDI++ G Y++ SLS QPGP V +GE+VTL C S+ + L Sbjct: 299 GA-HNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLL 357 Query: 256 SREGGAHERRLPAVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEWSDPSDPLLV 313 ++EG A + ++ +QA+FP+GP T H GTYRC+GS PY + PSDPL + Sbjct: 358 TKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLEL 417 Query: 314 SV---TGNPSSSWPSPTEPSS--------------KSGNPRHLHILIGTSVVIILFILLL 356 V +G PSS PT S+ +SG RHL ++IG V +IL +LLL Sbjct: 418 VVSGPSGGPSSPTTGPTSTSAGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVILLLLLL 477 Query: 357 FFLLHL---------WCSNKKNAAVMDQEPAG-------NRTANSEDSDEQD-PEEVTYA 399 L + W S ++ A Q PAG +R S D EE YA Sbjct: 478 LLLFLILRHRRQGKHWTSTQRKADF--QHPAGAVGPEPTDRGLQWRSSPAADAQEENLYA 535 Query: 400 QLDHCVFTQRKITRPSQRPKTPPTDTILYTELPNAKPRSKVVSCP 444 + H Q P + Y E+ +++PR ++ S P Sbjct: 536 AVKHTQPEDGVEMDTRQSPHDEDPQAVTYAEVKHSRPRREMASPP 580 Score = 203 bits (517), Expect = 2e-52 Identities = 132/346 (38%), Positives = 187/346 (54%), Gaps = 18/346 (5%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 M+ ++ + C+GL L R G KP L A P +V+ +G VTLRC + L Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60 Query: 61 YKEDRIHIPIFHGRIFQE-----SFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVI 115 Y+E + + I RI QE F + +T HAG Y C + G S S+P+ + Sbjct: 61 YREKKTALWIT--RIPQELVKKGQFPIPSITWEHAGRYRCY--YGSDTAGRSESSDPLEL 116 Query: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHD-G 174 +VTG + KP+L A P P+V SG VILQC S + F+ F L KEG + P L Q H G Sbjct: 117 VVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARG 176 Query: 175 VSKANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKV 234 S+A FS+GP+ + YRCY +++PY+ S PSD L+++V G +KPSLS QPGP V Sbjct: 177 SSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIV 236 Query: 235 QAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPA--THGGTYR 292 E++TL C S + Y+ + L ++G +L + QA+F LGP ++GG YR Sbjct: 237 APEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYR 296 Query: 293 CFGSFRHSPYEWSDPSDPLLVSVTGN-----PSSSWPSPTEPSSKS 333 C+G+ S EWS PSDPL + + G S P PT S ++ Sbjct: 297 CYGAHNLSS-EWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGEN 341 Score = 144 bits (364), Expect = 1e-34 Identities = 87/216 (40%), Positives = 118/216 (54%), Gaps = 8/216 (3%) Query: 23 MGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHIPIFHGR-----IFQ 77 +G KP LS P +V +TL+C +N F+LYK+ G + Q Sbjct: 220 LGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQ 279 Query: 78 ESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGN-HRKPSLLAHPGPLVKS 136 +F + PV+ ++ G Y C G+H S + WSAPS+P+ I++ G + + SL PGP V S Sbjct: 280 ANFTLGPVSRSYGGQYRCYGAHNLS-SEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVAS 338 Query: 137 GERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCY 196 GE V L C S + F L KEG + DP RL +A F +GP+ A AGTYRCY Sbjct: 339 GENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCY 398 Query: 197 GSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGP 232 GS + PY L+ PSDPL++VV+GP PS S GP Sbjct: 399 GSQSSKPYLLTHPSDPLELVVSGPSGGPS-SPTTGP 433 Score = 31.6 bits (70), Expect = 1.5 Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 3/58 (5%) Query: 374 DQEPAGNRTANSEDSDEQDPEEVTYAQLDHCVFTQRKITR--PSQRPKTPPTDTILYT 429 D++ +R ++E + + P++VTYAQL H + +R+ T PSQ +P +I T Sbjct: 592 DRQAEEDRQMDTEAAASEAPQDVTYAQL-HSLTLRREATEPPPSQEGPSPAVPSIYAT 648 >gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B, member 1 isoform 3 [Homo sapiens] Length = 651 Score = 239 bits (609), Expect = 5e-63 Identities = 167/465 (35%), Positives = 240/465 (51%), Gaps = 49/465 (10%) Query: 24 GGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHIPIF-----HGRIFQE 78 G KP LSA PS VV GG+V L+C + F+ F L KE P H R Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179 Query: 79 S-FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSG 137 + F++ PV+ + Y C +SP WS PS+ + ++V G +KPSL PGP+V Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239 Query: 138 ERVILQCWSDIMFEHFFLHKEGISKDPSRLVG-QIHDGVSKANFSIGPMMLALAGTYRCY 196 E + LQC SD + F L+K+G +D +L G Q G+S+ANF++GP+ + G YRCY Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDG-ERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCY 298 Query: 197 GSVTHTPYQLSAPSDPLDIVVTGP-YEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHL 255 G+ + + SAPSDPLDI++ G Y++ SLS QPGP V +GE+VTL C S+ + L Sbjct: 299 GA-HNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLL 357 Query: 256 SREGGAHERRLPAVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEWSDPSDPLLV 313 ++EG A + ++ +QA+FP+GP T H GTYRC+GS PY + PSDPL + Sbjct: 358 TKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLEL 417 Query: 314 SV---TGNPSSSWPSPTEPSS--------------KSGNPRHLHILIGTSVVIILFILLL 356 V +G PSS PT S+ +SG RHL ++IG V +IL +LLL Sbjct: 418 VVSGPSGGPSSPTTGPTSTSAGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVILLLLLL 477 Query: 357 FFLLHL---------WCSNKKNAAVMDQEPAG-------NRTANSEDSDEQD-PEEVTYA 399 L + W S ++ A Q PAG +R S D EE YA Sbjct: 478 LLLFLILRHRRQGKHWTSTQRKADF--QHPAGAVGPEPTDRGLQWRSSPAADAQEENLYA 535 Query: 400 QLDHCVFTQRKITRPSQRPKTPPTDTILYTELPNAKPRSKVVSCP 444 + H + + ++ P + Y E+ +++PR ++ S P Sbjct: 536 AVKH-TQPEDGVEMDTRSPHDEDPQAVTYAEVKHSRPRREMASPP 579 Score = 203 bits (517), Expect = 2e-52 Identities = 132/346 (38%), Positives = 187/346 (54%), Gaps = 18/346 (5%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 M+ ++ + C+GL L R G KP L A P +V+ +G VTLRC + L Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60 Query: 61 YKEDRIHIPIFHGRIFQE-----SFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVI 115 Y+E + + I RI QE F + +T HAG Y C + G S S+P+ + Sbjct: 61 YREKKTALWIT--RIPQELVKKGQFPIPSITWEHAGRYRCY--YGSDTAGRSESSDPLEL 116 Query: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHD-G 174 +VTG + KP+L A P P+V SG VILQC S + F+ F L KEG + P L Q H G Sbjct: 117 VVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARG 176 Query: 175 VSKANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKV 234 S+A FS+GP+ + YRCY +++PY+ S PSD L+++V G +KPSLS QPGP V Sbjct: 177 SSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIV 236 Query: 235 QAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPA--THGGTYR 292 E++TL C S + Y+ + L ++G +L + QA+F LGP ++GG YR Sbjct: 237 APEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYR 296 Query: 293 CFGSFRHSPYEWSDPSDPLLVSVTGN-----PSSSWPSPTEPSSKS 333 C+G+ S EWS PSDPL + + G S P PT S ++ Sbjct: 297 CYGAHNLSS-EWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGEN 341 Score = 144 bits (364), Expect = 1e-34 Identities = 87/216 (40%), Positives = 118/216 (54%), Gaps = 8/216 (3%) Query: 23 MGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHIPIFHGR-----IFQ 77 +G KP LS P +V +TL+C +N F+LYK+ G + Q Sbjct: 220 LGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQ 279 Query: 78 ESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGN-HRKPSLLAHPGPLVKS 136 +F + PV+ ++ G Y C G+H S + WSAPS+P+ I++ G + + SL PGP V S Sbjct: 280 ANFTLGPVSRSYGGQYRCYGAHNLS-SEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVAS 338 Query: 137 GERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCY 196 GE V L C S + F L KEG + DP RL +A F +GP+ A AGTYRCY Sbjct: 339 GENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCY 398 Query: 197 GSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGP 232 GS + PY L+ PSDPL++VV+GP PS S GP Sbjct: 399 GSQSSKPYLLTHPSDPLELVVSGPSGGPS-SPTTGP 433 Score = 31.6 bits (70), Expect = 1.5 Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 3/58 (5%) Query: 374 DQEPAGNRTANSEDSDEQDPEEVTYAQLDHCVFTQRKITR--PSQRPKTPPTDTILYT 429 D++ +R ++E + + P++VTYAQL H + +R+ T PSQ +P +I T Sbjct: 591 DRQAEEDRQMDTEAAASEAPQDVTYAQL-HSLTLRREATEPPPSQEGPSPAVPSIYAT 647 >gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B, member 1 isoform 1 [Homo sapiens] Length = 650 Score = 239 bits (609), Expect = 5e-63 Identities = 167/464 (35%), Positives = 239/464 (51%), Gaps = 48/464 (10%) Query: 24 GGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHIPIF-----HGRIFQE 78 G KP LSA PS VV GG+V L+C + F+ F L KE P H R Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179 Query: 79 S-FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSG 137 + F++ PV+ + Y C +SP WS PS+ + ++V G +KPSL PGP+V Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239 Query: 138 ERVILQCWSDIMFEHFFLHKEGISKDPSRLVG-QIHDGVSKANFSIGPMMLALAGTYRCY 196 E + LQC SD + F L+K+G +D +L G Q G+S+ANF++GP+ + G YRCY Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDG-ERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCY 298 Query: 197 GSVTHTPYQLSAPSDPLDIVVTGP-YEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHL 255 G+ + + SAPSDPLDI++ G Y++ SLS QPGP V +GE+VTL C S+ + L Sbjct: 299 GA-HNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLL 357 Query: 256 SREGGAHERRLPAVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEWSDPSDPLLV 313 ++EG A + ++ +QA+FP+GP T H GTYRC+GS PY + PSDPL + Sbjct: 358 TKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLEL 417 Query: 314 SV---TGNPSSSWPSPTEPSS-------------KSGNPRHLHILIGTSVVIILFILLLF 357 V +G PSS PT S +SG RHL ++IG V +IL +LLL Sbjct: 418 VVSGPSGGPSSPTTGPTSTSGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVILLLLLLL 477 Query: 358 FLLHL---------WCSNKKNAAVMDQEPAG-------NRTANSEDSDEQD-PEEVTYAQ 400 L + W S ++ A Q PAG +R S D EE YA Sbjct: 478 LLFLILRHRRQGKHWTSTQRKADF--QHPAGAVGPEPTDRGLQWRSSPAADAQEENLYAA 535 Query: 401 LDHCVFTQRKITRPSQRPKTPPTDTILYTELPNAKPRSKVVSCP 444 + H + + ++ P + Y E+ +++PR ++ S P Sbjct: 536 VKH-TQPEDGVEMDTRSPHDEDPQAVTYAEVKHSRPRREMASPP 578 Score = 203 bits (517), Expect = 2e-52 Identities = 132/346 (38%), Positives = 187/346 (54%), Gaps = 18/346 (5%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 M+ ++ + C+GL L R G KP L A P +V+ +G VTLRC + L Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60 Query: 61 YKEDRIHIPIFHGRIFQE-----SFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVI 115 Y+E + + I RI QE F + +T HAG Y C + G S S+P+ + Sbjct: 61 YREKKTALWIT--RIPQELVKKGQFPIPSITWEHAGRYRCY--YGSDTAGRSESSDPLEL 116 Query: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHD-G 174 +VTG + KP+L A P P+V SG VILQC S + F+ F L KEG + P L Q H G Sbjct: 117 VVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARG 176 Query: 175 VSKANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKV 234 S+A FS+GP+ + YRCY +++PY+ S PSD L+++V G +KPSLS QPGP V Sbjct: 177 SSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIV 236 Query: 235 QAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPA--THGGTYR 292 E++TL C S + Y+ + L ++G +L + QA+F LGP ++GG YR Sbjct: 237 APEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYR 296 Query: 293 CFGSFRHSPYEWSDPSDPLLVSVTGN-----PSSSWPSPTEPSSKS 333 C+G+ S EWS PSDPL + + G S P PT S ++ Sbjct: 297 CYGAHNLSS-EWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGEN 341 Score = 145 bits (367), Expect = 6e-35 Identities = 88/221 (39%), Positives = 120/221 (54%), Gaps = 8/221 (3%) Query: 23 MGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHIPIFHGR-----IFQ 77 +G KP LS P +V +TL+C +N F+LYK+ G + Q Sbjct: 220 LGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQ 279 Query: 78 ESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGN-HRKPSLLAHPGPLVKS 136 +F + PV+ ++ G Y C G+H S + WSAPS+P+ I++ G + + SL PGP V S Sbjct: 280 ANFTLGPVSRSYGGQYRCYGAHNLS-SEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVAS 338 Query: 137 GERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCY 196 GE V L C S + F L KEG + DP RL +A F +GP+ A AGTYRCY Sbjct: 339 GENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCY 398 Query: 197 GSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAG 237 GS + PY L+ PSDPL++VV+GP PS S GP +G Sbjct: 399 GSQSSKPYLLTHPSDPLELVVSGPSGGPS-SPTTGPTSTSG 438 Score = 31.6 bits (70), Expect = 1.5 Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 3/58 (5%) Query: 374 DQEPAGNRTANSEDSDEQDPEEVTYAQLDHCVFTQRKITR--PSQRPKTPPTDTILYT 429 D++ +R ++E + + P++VTYAQL H + +R+ T PSQ +P +I T Sbjct: 590 DRQAEEDRQMDTEAAASEAPQDVTYAQL-HSLTLRREATEPPPSQEGPSPAVPSIYAT 646 >gi|110611910 leukocyte immunoglobulin-like receptor, subfamily A, member 6 [Homo sapiens] Length = 481 Score = 239 bits (609), Expect = 5e-63 Identities = 143/363 (39%), Positives = 216/363 (59%), Gaps = 17/363 (4%) Query: 24 GGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHIPI------FHGRIFQ 77 G +KP LSA PS VV GG++TLRC + +++F+L KE +P H FQ Sbjct: 119 GFYNKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGGFQ 178 Query: 78 ESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSG 137 F + PVT +H +TC + ++P WS PS+P+ I+ +G RKPSLL GP++ G Sbjct: 179 ALFPVGPVTPSHRWRFTCYYYYTNTPRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPG 238 Query: 138 ERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYG 197 + + LQC SD+ ++ F L+KEG R Q G+S+ANF++GP+ + G YRCYG Sbjct: 239 QSLTLQCGSDVGYDRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSHGGQYRCYG 298 Query: 198 SVTHTPYQLSAPSDPLDIVVTGP-YEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLS 256 + + + SAPSDPL+I++ G Y+ SLSAQPGP V +GE+VTL C SR +D + L+ Sbjct: 299 A-HNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSRGYFDTFLLT 357 Query: 257 REGGAH-ERRLPAVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEWSDPSDPLLV 313 +EG AH RL ++ ++ +QA+FP+ P T H GTYRC+GS+ +P+ S PS+PL + Sbjct: 358 KEGAAHPPLRLRSMYGAHK-YQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSFPSEPLEL 416 Query: 314 SVTGNPSSSWPSPTEPSSKSGNPRHLH-----ILIGTSVVIILFILLLFFLLHLWCSNKK 368 V+G+ S PT P S + + I +G + ++++F+ +L F N + Sbjct: 417 MVSGHSGGSSLPPTGPPSTPASHAKDYTVENLIRMGMAGLVLVFLGILLFEAQHSQRNPQ 476 Query: 369 NAA 371 +AA Sbjct: 477 DAA 479 Score = 190 bits (482), Expect = 3e-48 Identities = 124/345 (35%), Positives = 177/345 (51%), Gaps = 17/345 (4%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 M+ + ++ C+GL L R G KP L A P +V+ G VT+ C + L Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSLEAQEYQL 60 Query: 61 YKEDRIHIPIFHGRIFQES----FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIM 116 KE P+ + F++ +T HAG Y C H +S GWS PS+P+ ++ Sbjct: 61 DKEGSPE-PLDRNNPLEPKNKARFSIPSMTQHHAGRYRC---HYYSSAGWSEPSDPLELV 116 Query: 117 VTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVG-QIHDGV 175 +TG + KP+L A P P+V SG + L+C S + HF L KEG + P L Q+H G Sbjct: 117 MTGFYNKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGG 176 Query: 176 SKANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQ 235 +A F +GP+ + + CY T+TP S PSDPL+I+ +G KPSL GP + Sbjct: 177 FQALFPVGPVTPSHRWRFTCYYYYTNTPRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLA 236 Query: 236 AGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPA--THGGTYRC 293 G+S+TL C S YD + L +EG + P + QA+F LGP +HGG YRC Sbjct: 237 PGQSLTLQCGSDVGYDRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSHGGQYRC 296 Query: 294 FGSFRHSPYEWSDPSDPLLVSVTGN-----PSSSWPSPTEPSSKS 333 +G+ S EWS PSDPL + + G S+ P PT S ++ Sbjct: 297 YGAHNLSS-EWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGEN 340 >gi|125987593 leukocyte immunoglobulin-like receptor, subfamily B, member 5 isoform 3 [Homo sapiens] Length = 491 Score = 228 bits (581), Expect = 8e-60 Identities = 163/494 (32%), Positives = 236/494 (47%), Gaps = 69/494 (13%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 M+L + + C+GL + R G KP L A P++V+ RG VTL C + L Sbjct: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60 Query: 61 YKED-----RIHIPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVI 115 KE + P+ G + F++ AG Y C + +P GWS PS+P+ + Sbjct: 61 DKEGLPWARKRQNPLEPGA--KAKFHIPSTVYDSAGRYRC---YYETPAGWSEPSDPLEL 115 Query: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGV 175 + TG RKPSLL G +V G + LQC SD+ ++ F L+KEG Q G+ Sbjct: 116 VATGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGL 175 Query: 176 SKANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPY-EKPSLSAQPGPKV 234 S+ANF++GP+ + G YRCYG+ +P + SAPSDPLDI++ G + P+LS QPGPKV Sbjct: 176 SQANFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKV 234 Query: 235 QAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPAT--HGGTYR 292 +GE+VTL C S D + L++EG AH + + QA+F + P T GGTYR Sbjct: 235 ASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYR 294 Query: 293 CFGSFRHSPYEWSDPSDPLLVSVTG-------NPSSSWPSPTEPSSK----------SGN 335 C+ + R PY S PS P + V+G +P+ S P+P P + SG Sbjct: 295 CYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGL 354 Query: 336 PRHLHILIGTSVVIILFI-LLLFFLLHLWCSNKK-------------------------- 368 RHL ++ G SV +L + LLLF LL +K Sbjct: 355 GRHLGVVTGVSVAFVLLLFLLLFLLLRHRHQSKHRTSAHFYRPAGAAGPEPKDQGLQKRA 414 Query: 369 -----------NAAVMDQEPAGNRTANSEDSDEQDPEEVTYAQLDHCVFTQRKITRPSQR 417 NAAV D +P ++ + + P++VTYAQL + P + Sbjct: 415 SPVADIQEEILNAAVKDTQPKDGVEMDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQ 474 Query: 418 PKTPPTDTILYTEL 431 + PP + +Y L Sbjct: 475 EREPPAEPSIYAPL 488 >gi|47519953 leukocyte immunoglobulin-like receptor subfamily A member 4 [Homo sapiens] Length = 499 Score = 225 bits (573), Expect = 7e-59 Identities = 139/349 (39%), Positives = 201/349 (57%), Gaps = 23/349 (6%) Query: 28 KPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHIPIF-------HGRIFQESF 80 +P LSA PS VV G +VTLRC R F L +E + HG+ FQ F Sbjct: 122 RPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGK-FQALF 180 Query: 81 NMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGERV 140 M P+T ++ G + C G ++P WS PS+P+ ++V+G RKPSLL GP+V GE + Sbjct: 181 PMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGENL 240 Query: 141 ILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYGSVT 200 LQC SD+ + + L+KEG P R Q G+S+ANF++ P+ + G YRCYG+ Sbjct: 241 TLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGA-H 299 Query: 201 HTPYQLSAPSDPLDIVVTGPY-EKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREG 259 + + SAPSDPLDI++ G ++PSLS QPGP V +GE VTL C S + L++EG Sbjct: 300 NVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEG 359 Query: 260 GAH-ERRLPAVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEWSDPSDPLLVSVT 316 AH RL ++ ++ +QA+FP+ P T H GTYRC+GS +PY S PS+PL + V+ Sbjct: 360 AAHPPLRLRSMYGAHK-YQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVS 418 Query: 317 GNPSSSWPSPTEPSSKSGNPRHLH-------ILIGTSVVIILFILLLFF 358 G ++ +P + S S HL I +G + +++LF+ +L F Sbjct: 419 G--ATETLNPAQKKSDSKTAPHLQDYTVENLIRMGVAGLVLLFLGILLF 465 Score = 171 bits (433), Expect = 1e-42 Identities = 122/343 (35%), Positives = 169/343 (49%), Gaps = 16/343 (4%) Query: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 M+L++ S+ GL L R KP L A P V+ VT+ C + L Sbjct: 1 MTLILTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRL 60 Query: 61 YKEDRI---HIPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMV 117 KE HI + ++ + HAG Y C + SP GWS PS+P+ ++V Sbjct: 61 DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHC---YYQSPAGWSEPSDPLELVV 117 Query: 118 TGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHD-GVS 176 T + +P+L A P P+V SG V L+C S + F L +EG + L H+ G Sbjct: 118 TA-YSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKF 176 Query: 177 KANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQA 236 +A F +GP+ + GT+RCYG +TPY S PSDPL ++V+G KPSL GP V Sbjct: 177 QALFPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTP 236 Query: 237 GESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPA--THGGTYRCF 294 GE++TL C S Y Y L +EG + P + QA+F L P ++GG YRC+ Sbjct: 237 GENLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCY 296 Query: 295 GSFRHSPYEWSDPSDPLLVSVTGNPS-----SSWPSPTEPSSK 332 G+ S EWS PSDPL + + G S S P PT S + Sbjct: 297 GAHNVSS-EWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGE 338 Score = 68.2 bits (165), Expect = 1e-11 Identities = 39/98 (39%), Positives = 50/98 (51%), Gaps = 5/98 (5%) Query: 27 DKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHIPI-----FHGRIFQESFN 81 D+P LS P V G VTL C F+L KE H P+ + +Q F Sbjct: 322 DRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEGAAHPPLRLRSMYGAHKYQAEFP 381 Query: 82 MSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTG 119 MSPVT+AHAG Y C GS +P S PS P+ ++V+G Sbjct: 382 MSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSG 419 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.135 0.428 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,882,507 Number of Sequences: 37866 Number of extensions: 1106533 Number of successful extensions: 4672 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 79 Number of HSP's successfully gapped in prelim test: 48 Number of HSP's that attempted gapping in prelim test: 3643 Number of HSP's gapped (non-prelim): 325 length of query: 444 length of database: 18,247,518 effective HSP length: 105 effective length of query: 339 effective length of database: 14,271,588 effective search space: 4838068332 effective search space used: 4838068332 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.