BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|134268642 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 precursor [Homo sapiens] (455 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|134268642 killer cell immunoglobulin-like receptor, three dom... 947 0.0 gi|134268644 killer cell immunoglobulin-like receptor, three dom... 786 0.0 gi|46488946 killer cell immunoglobulin-like receptor, three doma... 651 0.0 gi|134133244 killer cell immunoglobulin-like receptor, three dom... 640 0.0 gi|71143139 killer cell immunoglobulin-like receptor, two domain... 554 e-158 gi|134304833 killer cell immunoglobulin-like receptor, two domai... 552 e-157 gi|110611923 killer cell immunoglobulin-like receptor, two domai... 544 e-155 gi|62632748 killer-cell Ig-like receptor [Homo sapiens] 502 e-142 gi|6912472 killer cell immunoglobulin-like receptor, two domains... 482 e-136 gi|116517309 killer cell immunoglobulin-like receptor, two domai... 479 e-135 gi|7657277 killer cell immunoglobulin-like receptor, two domains... 466 e-131 gi|6912474 killer cell immunoglobulin-like receptor, two domains... 463 e-130 gi|134304835 killer cell immunoglobulin-like receptor, two domai... 461 e-130 gi|11968154 killer cell immunoglobulin-like receptor, two domain... 416 e-116 gi|124107606 killer cell immunoglobulin-like receptor, two domai... 415 e-116 gi|66267727 killer cell immunoglobulin-like receptor, two domain... 405 e-113 gi|124107610 killer cell immunoglobulin-like receptor, two domai... 348 4e-96 gi|124107604 killer cell immunoglobulin-like receptor, two domai... 300 2e-81 gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B... 289 4e-78 gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B... 287 2e-77 gi|71143143 killer cell immunoglobulin-like receptor, two domain... 278 6e-75 gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B... 261 9e-70 gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B... 261 1e-69 gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B... 252 4e-67 gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B... 252 4e-67 gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B... 252 4e-67 gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B... 252 4e-67 gi|110611910 leukocyte immunoglobulin-like receptor, subfamily A... 243 3e-64 gi|125987591 leukocyte immunoglobulin-like receptor, subfamily B... 234 1e-61 gi|5803070 leukocyte immunoglobulin-like receptor, subfamily B, ... 232 5e-61 >gi|134268642 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 precursor [Homo sapiens] Length = 455 Score = 947 bits (2447), Expect = 0.0 Identities = 455/455 (100%), Positives = 455/455 (100%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML Sbjct: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 Query: 61 YKEDRSHVPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGN 120 YKEDRSHVPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGN Sbjct: 61 YKEDRSHVPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGN 120 Query: 121 HRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANF 180 HRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANF Sbjct: 121 HRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANF 180 Query: 181 SIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGENV 240 SIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGENV Sbjct: 181 SIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGENV 240 Query: 241 TLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPATHGGTYRCFGSFRAL 300 TLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPATHGGTYRCFGSFRAL Sbjct: 241 TLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPATHGGTYRCFGSFRAL 300 Query: 301 PCVWSNSSDPLLVSVTGNPSSSWPSPTEPSSKSGICRHLHVLIGTSVVIFLFILLLFFLL 360 PCVWSNSSDPLLVSVTGNPSSSWPSPTEPSSKSGICRHLHVLIGTSVVIFLFILLLFFLL Sbjct: 301 PCVWSNSSDPLLVSVTGNPSSSWPSPTEPSSKSGICRHLHVLIGTSVVIFLFILLLFFLL 360 Query: 361 YRWCSNKKNAAVMDQEPAGDRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISRPSQRPKT 420 YRWCSNKKNAAVMDQEPAGDRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISRPSQRPKT Sbjct: 361 YRWCSNKKNAAVMDQEPAGDRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISRPSQRPKT 420 Query: 421 PLTDTSVYTELPNAEPRSKVVSCPRAPQSGLEGVF 455 PLTDTSVYTELPNAEPRSKVVSCPRAPQSGLEGVF Sbjct: 421 PLTDTSVYTELPNAEPRSKVVSCPRAPQSGLEGVF 455 >gi|134268644 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 precursor [Homo sapiens] Length = 444 Score = 786 bits (2031), Expect = 0.0 Identities = 380/444 (85%), Positives = 402/444 (90%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 MSL VVSMACVG FL+Q A P MGGQDKPFLSA PS VVPRGGHV L+CHYR FNNFML Sbjct: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 Query: 61 YKEDRSHVPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGN 120 YKEDR H+PIFHGRIFQESF M PVT AHAG Y CRGS PHS TGWSAPSNP+VIMVTGN Sbjct: 61 YKEDRIHIPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGN 120 Query: 121 HRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANF 180 HRKPSLLAHPGPL+KSGE VILQCWSD+MFEHFFLH+EGIS+DPSRLVGQIHDGVSKANF Sbjct: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANF 180 Query: 181 SIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGENV 240 SIGP+M LAGTYRCYGSV H+PYQLSAPSDPLDIV+TG YEKPSLSAQPGP VQAGE+V Sbjct: 181 SIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESV 240 Query: 241 TLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPATHGGTYRCFGSFRAL 300 TLSCSS SSYD+YHLSREG AHERRL AV KVNRTFQADFPLGPATHGGTYRCFGSFR Sbjct: 241 TLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHS 300 Query: 301 PCVWSNSSDPLLVSVTGNPSSSWPSPTEPSSKSGICRHLHVLIGTSVVIFLFILLLFFLL 360 P WS+ SDPLLVSVTGNPSSSWPSPTEPSSKSG RHLH+LIGTSVVI LFILLLFFLL Sbjct: 301 PYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNPRHLHILIGTSVVIILFILLLFFLL 360 Query: 361 YRWCSNKKNAAVMDQEPAGDRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISRPSQRPKT 420 + WCSNKKNAAVMDQEPAG+RT N +DSDEQDP+EVTYAQLDHCVF QRKI+RPSQRPKT Sbjct: 361 HLWCSNKKNAAVMDQEPAGNRTANSEDSDEQDPEEVTYAQLDHCVFTQRKITRPSQRPKT 420 Query: 421 PLTDTSVYTELPNAEPRSKVVSCP 444 P TDT +YTELPNA+PRSKVVSCP Sbjct: 421 PPTDTILYTELPNAKPRSKVVSCP 444 >gi|46488946 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 [Homo sapiens] Length = 410 Score = 651 bits (1679), Expect = 0.0 Identities = 322/427 (75%), Positives = 349/427 (81%), Gaps = 17/427 (3%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 MSL VVSMACVGFFLL+G WP +GGQDKPFLSA P TVV G HV LQC R GFN F L Sbjct: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60 Query: 61 YKEDRSHVPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGN 120 KED VP + RIF+ SF+MGPVTPAHAGTYRC S PHS TGWSAPSNP+VIMVTG Sbjct: 61 SKEDGMPVPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGV 120 Query: 121 HRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANF 180 HRKPSLLAHPGPL+KSGETVILQCWSDV FE F LHREGI+EDP RLVGQ+HD S+ N+ Sbjct: 121 HRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNY 180 Query: 181 SIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGENV 240 S+GP+ P LAGTYRC+GSV H PY+LSAPSDPLDIV+ GLY KPSLSAQPGPTVQAGENV Sbjct: 181 SMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGENV 240 Query: 241 TLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPATHGGTYRCFGSFRAL 300 TLSCSS S +DIYHLSRE EA E RL AV +VN TFQA+FPLGP THGG YRCFGSFRAL Sbjct: 241 TLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFRAL 300 Query: 301 PCVWSNSSDPLLVSVTGNPSSSWPSPTEPSSKSGICRHLHVLIGTSVVIFLFILLLFFLL 360 P WS+ SDPL VSVTGN RHLHVLIGTSVVI F +LLFFLL Sbjct: 301 PHAWSDPSDPLPVSVTGN-----------------SRHLHVLIGTSVVIIPFAILLFFLL 343 Query: 361 YRWCSNKKNAAVMDQEPAGDRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISRPSQRPKT 420 +RWC+NKKNA VMDQEPAG+RTVNR+DSDEQDPQEVTYAQL+HCVF QRKI+RPSQRPKT Sbjct: 344 HRWCANKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKT 403 Query: 421 PLTDTSV 427 P TDTSV Sbjct: 404 PPTDTSV 410 >gi|134133244 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1 [Homo sapiens] Length = 382 Score = 640 bits (1652), Expect = 0.0 Identities = 310/368 (84%), Positives = 326/368 (88%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 M L VVSMACVG FL+Q A P MGGQDKPFLSA PS VVPRGGHV L+CHYR FNNFML Sbjct: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60 Query: 61 YKEDRSHVPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGN 120 YKEDR HVPIFHGRIFQE F M PVT AHAG Y CRGS PHS TGWSAPSNP+VIMVTGN Sbjct: 61 YKEDRIHVPIFHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGN 120 Query: 121 HRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANF 180 HRKPSLLAHPGPL+KSGE VILQCWSD+MFEHFFLH+E IS+DPSRLVGQIHDGVSKANF Sbjct: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANF 180 Query: 181 SIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGENV 240 SIG +M LAGTYRCYGSV H+PYQLSAPSDPLDIV+TGLYEKPSLSAQPGP VQAGE+V Sbjct: 181 SIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESV 240 Query: 241 TLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPATHGGTYRCFGSFRAL 300 TLSCSS SSYD+YHLSREG AHERRL AV KVNRTFQADFPLGPATHGGTYRCFGSFR Sbjct: 241 TLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHS 300 Query: 301 PCVWSNSSDPLLVSVTGNPSSSWPSPTEPSSKSGICRHLHVLIGTSVVIFLFILLLFFLL 360 P WS+ SDPLLVSVTGNPSSSWPSPTEPSSKSG RHLH+LIGTSVV F +LLFFLL Sbjct: 301 PYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFFLL 360 Query: 361 YRWCSNKK 368 +RWCSNKK Sbjct: 361 HRWCSNKK 368 >gi|71143139 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 isoform 2 [Homo sapiens] Length = 341 Score = 554 bits (1428), Expect = e-158 Identities = 270/318 (84%), Positives = 286/318 (89%) Query: 119 GNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKA 178 G HRKPSLLAHPGPL+KS ETVILQCWSDV F+HF LHREG +D L+G+ HDGVSKA Sbjct: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 Query: 179 NFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGE 238 NFSIGP+M LAGTYRCYGSV HSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTV AGE Sbjct: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGE 143 Query: 239 NVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPATHGGTYRCFGSFR 298 +VTLSCSS SSYD+YHLSREGEAHERR A PKVN TFQADFPLGPATHGGTYRCFGSFR Sbjct: 144 SVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFR 203 Query: 299 ALPCVWSNSSDPLLVSVTGNPSSSWPSPTEPSSKSGICRHLHVLIGTSVVIFLFILLLFF 358 P WSNSSDPLLVSVTGNPS+SWPSPTEPSS++G RHLHVLIGTSVVI LFILLLFF Sbjct: 204 DSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSETGNPRHLHVLIGTSVVIILFILLLFF 263 Query: 359 LLYRWCSNKKNAAVMDQEPAGDRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISRPSQRP 418 LL+RWC NKKNA VMDQEPAG+RTVNR+DSDEQDPQEVTYAQL+HCVF QRKI+RPSQRP Sbjct: 264 LLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRP 323 Query: 419 KTPLTDTSVYTELPNAEP 436 KTP TD VYTELPNAEP Sbjct: 324 KTPPTDIIVYTELPNAEP 341 Score = 172 bits (436), Expect = 6e-43 Identities = 106/243 (43%), Positives = 140/243 (57%), Gaps = 11/243 (4%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 MSL VVSM CVGFFLLQGAWP G KP L A P +V V LQC F +F+L Sbjct: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 Query: 61 YKE----DRSH-VPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVI 115 ++E D H + H + + +F +GP+ AGTYRC GS HS SAPS+PL I Sbjct: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120 Query: 116 MVTGNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGV 175 ++TG + KPSL A PGP + +GE+V L C S ++ + L REG + + G +G Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGT 180 Query: 176 SKANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQ 235 +A+F +GP GTYRC+GS SPY+ S SDPL + +TG PS ++ P PT Sbjct: 181 FQADFPLGP--ATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTG---NPS-NSWPSPTEP 234 Query: 236 AGE 238 + E Sbjct: 235 SSE 237 >gi|134304833 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 precursor [Homo sapiens] Length = 348 Score = 552 bits (1423), Expect = e-157 Identities = 279/360 (77%), Positives = 298/360 (82%), Gaps = 17/360 (4%) Query: 85 VTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGNHRKPSLLAHPGPLLKSGETVILQC 144 V+ A G + +G+ PH G HRKPSLLAHPG L+KS ETVILQC Sbjct: 6 VSMACVGFFLLQGAWPHE----------------GVHRKPSLLAHPGRLVKSEETVILQC 49 Query: 145 WSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANFSIGPLMPVLAGTYRCYGSVPHSPY 204 WSDV FEHF LHREG +D L+G+ HDGVSKANFSIGP+M LAGTYRCYGSV HSPY Sbjct: 50 WSDVRFEHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPY 109 Query: 205 QLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGENVTLSCSSWSSYDIYHLSREGEAHER 264 QLSAPSDPLDIVITGLYEKPSLSAQPGPTV AGE+VTLSCSS SSYD+YHLSREGEAHE Sbjct: 110 QLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHEC 169 Query: 265 RLRAVPKVNRTFQADFPLGPATHGGTYRCFGSFRALPCVWSNSSDPLLVSVTGNPSSSWP 324 R A PKVN TFQADFPLGPATHGGTYRCFGSFR P WSNSSDPLLVSVTGNPS+SWP Sbjct: 170 RFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWP 229 Query: 325 SPTEPSSKSGICRHLHVLIGTSVVIFLFILLLFFLLYRWCSNKKNAAVMDQEPAGDRTVN 384 SPTEPSSK+G RHLH+LIGTSVVI LFI LLFFLL+RWCSNKKNAAVMDQE AG+RT N Sbjct: 230 SPTEPSSKTGNPRHLHILIGTSVVIILFI-LLFFLLHRWCSNKKNAAVMDQESAGNRTAN 288 Query: 385 RQDSDEQDPQEVTYAQLDHCVFIQRKISRPSQRPKTPLTDTSVYTELPNAEPRSKVVSCP 444 +DSDEQDPQEVTY QL+HCVF QRKI+RPSQRPKTP TD VYTELPNAE RSKVVSCP Sbjct: 289 SEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP 348 Score = 172 bits (436), Expect = 6e-43 Identities = 106/238 (44%), Positives = 139/238 (58%), Gaps = 11/238 (4%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 MSL VVSMACVGFFLLQGAWP G KP L A P +V V LQC F +F+L Sbjct: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60 Query: 61 YKE----DRSH-VPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVI 115 ++E D H + H + + +F +GP+ AGTYRC GS HS SAPS+PL I Sbjct: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120 Query: 116 MVTGNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGV 175 ++TG + KPSL A PGP + +GE+V L C S ++ + L REG + + G +G Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT 180 Query: 176 SKANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPT 233 +A+F +GP GTYRC+GS SPY+ S SDPL + +TG PS ++ P PT Sbjct: 181 FQADFPLGP--ATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTG---NPS-NSWPSPT 232 >gi|110611923 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 [Homo sapiens] Length = 348 Score = 544 bits (1402), Expect = e-155 Identities = 276/360 (76%), Positives = 295/360 (81%), Gaps = 17/360 (4%) Query: 85 VTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGNHRKPSLLAHPGPLLKSGETVILQC 144 V+ A G + +G+ PH G HRKPSLLAHPG L+KS ETVILQC Sbjct: 6 VSMACVGFFLLQGAWPHE----------------GVHRKPSLLAHPGRLVKSEETVILQC 49 Query: 145 WSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANFSIGPLMPVLAGTYRCYGSVPHSPY 204 WSDVMFEHF LHREG+ D RL+G+ HDGVSKANFSI + LAGTYRCYGSV HSPY Sbjct: 50 WSDVMFEHFLLHREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPY 109 Query: 205 QLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGENVTLSCSSWSSYDIYHLSREGEAHER 264 Q+SAPSDPLDIVI GLYEKPSLSAQ GPTV AGENVTLSCSS SSYD+YHLSREGEAHER Sbjct: 110 QVSAPSDPLDIVIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHER 169 Query: 265 RLRAVPKVNRTFQADFPLGPATHGGTYRCFGSFRALPCVWSNSSDPLLVSVTGNPSSSWP 324 RL A PKVN TFQADFPLGPATHGGTYRCFGSF P WS SSDPLLVSVTGNPS+SWP Sbjct: 170 RLPAGPKVNGTFQADFPLGPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWP 229 Query: 325 SPTEPSSKSGICRHLHVLIGTSVVIFLFILLLFFLLYRWCSNKKNAAVMDQEPAGDRTVN 384 SPTEPSSK+G RHLH+LIGTSVVI LFI LLFFLL+RWCSNKKNAAVMDQE AG+RT N Sbjct: 230 SPTEPSSKTGNPRHLHILIGTSVVIILFI-LLFFLLHRWCSNKKNAAVMDQESAGNRTAN 288 Query: 385 RQDSDEQDPQEVTYAQLDHCVFIQRKISRPSQRPKTPLTDTSVYTELPNAEPRSKVVSCP 444 +DSDEQDPQEVTY QL+HCVF QRKI+RPSQRPKTP TD VYTELPNAE RSKVVSCP Sbjct: 289 SEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP 348 Score = 161 bits (407), Expect = 1e-39 Identities = 101/238 (42%), Positives = 134/238 (56%), Gaps = 11/238 (4%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 MSL VVSMACVGFFLLQGAWP G KP L A P +V V LQC F +F+L Sbjct: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60 Query: 61 YKEDRSHVPI-----FHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVI 115 ++E + + H + + +F + +T AGTYRC GS HS SAPS+PL I Sbjct: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120 Query: 116 MVTGNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGV 175 ++ G + KPSL A GP + +GE V L C S ++ + L REG + + G +G Sbjct: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGT 180 Query: 176 SKANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPT 233 +A+F +GP GTYRC+GS SPY+ S SDPL + +TG PS ++ P PT Sbjct: 181 FQADFPLGP--ATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTG---NPS-NSWPSPT 232 >gi|62632748 killer-cell Ig-like receptor [Homo sapiens] Length = 328 Score = 502 bits (1293), Expect = e-142 Identities = 249/316 (78%), Positives = 263/316 (83%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 MSL V+SMACVGFFLLQGAW GGQDKPFLSA PS VV G HVALQC R GFN F L Sbjct: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPFLSAWPSPVVSEGEHVALQCRSRLGFNEFSL 60 Query: 61 YKEDRSHVPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGN 120 KED VP + R+F+ + +GPVTPAHAGTYRCRGS PH LTGWSAPSNPLVIMVTG Sbjct: 61 SKEDGMPVPELYNRVFRNTVFIGPVTPAHAGTYRCRGSHPHFLTGWSAPSNPLVIMVTGV 120 Query: 121 HRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANF 180 HRKPSLLAHPGPL+KS ETVILQCWSDVMFEHF LHREG D RL G++HDGVSKANF Sbjct: 121 HRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLLHREGKFNDTLRLTGELHDGVSKANF 180 Query: 181 SIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGENV 240 SIG + LAGTYRCYGSVPHSPYQLSAPSDPLDIVITGL KPSLSAQP P V+AGE+V Sbjct: 181 SIGRMTQDLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLCGKPSLSAQPRPMVKAGESV 240 Query: 241 TLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPATHGGTYRCFGSFRAL 300 TLSCSS SSYDIYHLSREGEAHE R AVPKVN TFQA+FPLGPATHGGTYRCFGSFR Sbjct: 241 TLSCSSRSSYDIYHLSREGEAHELRFPAVPKVNGTFQANFPLGPATHGGTYRCFGSFRDS 300 Query: 301 PCVWSNSSDPLLVSVT 316 P WS+ SDPLLVSVT Sbjct: 301 PYEWSDLSDPLLVSVT 316 Score = 131 bits (330), Expect = 1e-30 Identities = 86/221 (38%), Positives = 120/221 (54%), Gaps = 11/221 (4%) Query: 119 GNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKA 178 G KP L A P P++ GE V LQC S + F F L S++ V ++++ V + Sbjct: 24 GGQDKPFLSAWPSPVVSEGEHVALQCRSRLGFNEFSL-----SKEDGMPVPELYNRVFRN 78 Query: 179 NFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGE 238 IGP+ P AGTYRC GS PH SAPS+PL I++TG++ KPSL A PGP V++ E Sbjct: 79 TVFIGPVTPAHAGTYRCRGSHPHFLTGWSAPSNPLVIMVTGVHRKPSLLAHPGPLVKSEE 138 Query: 239 NVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPATH--GGTYRCFGS 296 V L C S ++ + L REG+ ++ + +A+F +G T GTYRC+GS Sbjct: 139 TVILQCWSDVMFEHFLLHREGKFNDTLRLTGELHDGVSKANFSIGRMTQDLAGTYRCYGS 198 Query: 297 FRALPCVWSNSSDPLLVSVT---GNPS-SSWPSPTEPSSKS 333 P S SDPL + +T G PS S+ P P + +S Sbjct: 199 VPHSPYQLSAPSDPLDIVITGLCGKPSLSAQPRPMVKAGES 239 Score = 63.5 bits (153), Expect = 4e-10 Identities = 40/102 (39%), Positives = 56/102 (54%), Gaps = 9/102 (8%) Query: 28 KPFLSARPSTVVPRGGHVALQCHYRRGFNNFMLYKEDRSH------VPIFHGRIFQESFI 81 KP LSA+P +V G V L C R ++ + L +E +H VP +G FQ +F Sbjct: 223 KPSLSAQPRPMVKAGESVTLSCSSRSSYDIYHLSREGEAHELRFPAVPKVNGT-FQANFP 281 Query: 82 MGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGNHRK 123 +GP T H GTYRC GS S WS S+PL++ VT + ++ Sbjct: 282 LGPAT--HGGTYRCFGSFRDSPYEWSDLSDPLLVSVTDSMKE 321 >gi|6912472 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2 precursor [Homo sapiens] Length = 304 Score = 482 bits (1240), Expect = e-136 Identities = 242/315 (76%), Positives = 260/315 (82%), Gaps = 16/315 (5%) Query: 85 VTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGNHRKPSLLAHPGPLLKSGETVILQC 144 V+ A G + +G+ PH G HRKPSLLAHPGPL+KS ETVILQC Sbjct: 6 VSMACVGFFLLQGAWPHE----------------GVHRKPSLLAHPGPLVKSEETVILQC 49 Query: 145 WSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANFSIGPLMPVLAGTYRCYGSVPHSPY 204 WSDV FEHF LHREG +D L+G+ HDGVSKANFSIGP+M LAGTYRCYGSV HSPY Sbjct: 50 WSDVRFEHFLLHREGKYKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPY 109 Query: 205 QLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGENVTLSCSSWSSYDIYHLSREGEAHER 264 QLSAPSDPLDIVITGLYEKPSLSAQPGPTV AGE+VTLSCSS SSYD+YHLSREGEAHER Sbjct: 110 QLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHER 169 Query: 265 RLRAVPKVNRTFQADFPLGPATHGGTYRCFGSFRALPCVWSNSSDPLLVSVTGNPSSSWP 324 R A PKVN TFQADFPLGPATHGGTYRCFGSFR P WSNSSDPLLVSVTGNPS+SWP Sbjct: 170 RFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWP 229 Query: 325 SPTEPSSKSGICRHLHVLIGTSVVIFLFILLLFFLLYRWCSNKKNAAVMDQEPAGDRTVN 384 SPTEPSSK+G RHLHVLIGTSVV F +LLFFLL+RWCSNKKNAAVMDQEPAG+RTVN Sbjct: 230 SPTEPSSKTGNPRHLHVLIGTSVVKIPFTILLFFLLHRWCSNKKNAAVMDQEPAGNRTVN 289 Query: 385 RQDSDEQDPQEVTYA 399 +DSDEQD QEV+YA Sbjct: 290 SEDSDEQDHQEVSYA 304 Score = 172 bits (437), Expect = 4e-43 Identities = 106/238 (44%), Positives = 139/238 (58%), Gaps = 11/238 (4%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 MSL VVSMACVGFFLLQGAWP G KP L A P +V V LQC F +F+L Sbjct: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFEHFLL 60 Query: 61 YKE----DRSH-VPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVI 115 ++E D H + H + + +F +GP+ AGTYRC GS HS SAPS+PL I Sbjct: 61 HREGKYKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120 Query: 116 MVTGNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGV 175 ++TG + KPSL A PGP + +GE+V L C S ++ + L REG + + G +G Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGT 180 Query: 176 SKANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPT 233 +A+F +GP GTYRC+GS SPY+ S SDPL + +TG PS ++ P PT Sbjct: 181 FQADFPLGP--ATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTG---NPS-NSWPSPT 232 >gi|116517309 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4 [Homo sapiens] Length = 304 Score = 479 bits (1232), Expect = e-135 Identities = 234/281 (83%), Positives = 250/281 (88%) Query: 119 GNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKA 178 G HRKPS LA PG L+KS ETVILQCWSDVMFEHF LHREG + L+G+ HDGVSKA Sbjct: 24 GVHRKPSFLALPGHLVKSEETVILQCWSDVMFEHFLLHREGKFNNTLHLIGEHHDGVSKA 83 Query: 179 NFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGE 238 NFSIGP+MPVLAGTYRCYGSVPHSPYQLSAPSDPLD+VI GLYEKPSLSAQPGPTVQAGE Sbjct: 84 NFSIGPMMPVLAGTYRCYGSVPHSPYQLSAPSDPLDMVIIGLYEKPSLSAQPGPTVQAGE 143 Query: 239 NVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPATHGGTYRCFGSFR 298 NVTLSCSS SSYD+YHLSREGEAHERRL AV +N TFQADFPLGPATHGGTYRCFGSFR Sbjct: 144 NVTLSCSSRSSYDMYHLSREGEAHERRLPAVRSINGTFQADFPLGPATHGGTYRCFGSFR 203 Query: 299 ALPCVWSNSSDPLLVSVTGNPSSSWPSPTEPSSKSGICRHLHVLIGTSVVIFLFILLLFF 358 P WSNSSDPLLVSVTGNPS+SWPSPTEPSSK+G RHLHVLIGTSVV F +LLFF Sbjct: 204 DAPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGNPRHLHVLIGTSVVKIPFTILLFF 263 Query: 359 LLYRWCSNKKNAAVMDQEPAGDRTVNRQDSDEQDPQEVTYA 399 LL+RWCS+KKNAAVMDQEPAG+RTVN +DSDEQD QEV+YA Sbjct: 264 LLHRWCSDKKNAAVMDQEPAGNRTVNSEDSDEQDHQEVSYA 304 Score = 168 bits (425), Expect = 1e-41 Identities = 99/238 (41%), Positives = 138/238 (57%), Gaps = 11/238 (4%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 MSL V+ MACVGFFLLQGAWP G KP A P +V V LQC F +F+L Sbjct: 1 MSLMVIIMACVGFFLLQGAWPQEGVHRKPSFLALPGHLVKSEETVILQCWSDVMFEHFLL 60 Query: 61 YKEDRSHVPIF-----HGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVI 115 ++E + + + H + + +F +GP+ P AGTYRC GS PHS SAPS+PL + Sbjct: 61 HREGKFNNTLHLIGEHHDGVSKANFSIGPMMPVLAGTYRCYGSVPHSPYQLSAPSDPLDM 120 Query: 116 MVTGNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGV 175 ++ G + KPSL A PGP +++GE V L C S ++ + L REG + + + +G Sbjct: 121 VIIGLYEKPSLSAQPGPTVQAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAVRSINGT 180 Query: 176 SKANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPT 233 +A+F +GP GTYRC+GS +PY+ S SDPL + +TG PS ++ P PT Sbjct: 181 FQADFPLGP--ATHGGTYRCFGSFRDAPYEWSNSSDPLLVSVTG---NPS-NSWPSPT 232 >gi|7657277 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 precursor [Homo sapiens] Length = 304 Score = 466 bits (1198), Expect = e-131 Identities = 236/315 (74%), Positives = 256/315 (81%), Gaps = 16/315 (5%) Query: 85 VTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGNHRKPSLLAHPGPLLKSGETVILQC 144 V+ A G + +G+ PH G HRKPSLLAHPG L+KS ETVILQC Sbjct: 6 VSMACVGFFLLQGAWPHE----------------GVHRKPSLLAHPGRLVKSEETVILQC 49 Query: 145 WSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANFSIGPLMPVLAGTYRCYGSVPHSPY 204 WSDVMFEHF LHREG+ D RL+G+ HDGVSKANFSI + LAGTYRCYGSV HSPY Sbjct: 50 WSDVMFEHFLLHREGMFNDTLRLIGEHHDGVSKANFSISRMKQDLAGTYRCYGSVTHSPY 109 Query: 205 QLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGENVTLSCSSWSSYDIYHLSREGEAHER 264 QLSAPSDPLDIVI GLYEKPSLSAQPGPTV AGENVTLSCSS SSYD+YHLSREGEAHER Sbjct: 110 QLSAPSDPLDIVIIGLYEKPSLSAQPGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHER 169 Query: 265 RLRAVPKVNRTFQADFPLGPATHGGTYRCFGSFRALPCVWSNSSDPLLVSVTGNPSSSWP 324 RL A KVN TFQA+FPLGPATHGGTYRCFGSFR P WS SSDPLLVSVTGNPS+SWP Sbjct: 170 RLPAGTKVNGTFQANFPLGPATHGGTYRCFGSFRDSPYEWSKSSDPLLVSVTGNPSNSWP 229 Query: 325 SPTEPSSKSGICRHLHVLIGTSVVIFLFILLLFFLLYRWCSNKKNAAVMDQEPAGDRTVN 384 SPTEPSS++G RHLHVLIGTSVV F +LLFFLL+RWCS+KKNAAVMDQEPAG+RTVN Sbjct: 230 SPTEPSSETGNPRHLHVLIGTSVVKIPFTILLFFLLHRWCSDKKNAAVMDQEPAGNRTVN 289 Query: 385 RQDSDEQDPQEVTYA 399 +DSDEQD QEV+YA Sbjct: 290 SEDSDEQDHQEVSYA 304 Score = 168 bits (426), Expect = 8e-42 Identities = 104/243 (42%), Positives = 137/243 (56%), Gaps = 11/243 (4%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 MSLTVVSMACVGFFLLQGAWP G KP L A P +V V LQC F +F+L Sbjct: 1 MSLTVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60 Query: 61 YKEDRSHVPI-----FHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVI 115 ++E + + H + + +F + + AGTYRC GS HS SAPS+PL I Sbjct: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMKQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120 Query: 116 MVTGNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGV 175 ++ G + KPSL A PGP + +GE V L C S ++ + L REG + + G +G Sbjct: 121 VIIGLYEKPSLSAQPGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGTKVNGT 180 Query: 176 SKANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQ 235 +ANF +GP GTYRC+GS SPY+ S SDPL + +TG PS ++ P PT Sbjct: 181 FQANFPLGP--ATHGGTYRCFGSFRDSPYEWSKSSDPLLVSVTG---NPS-NSWPSPTEP 234 Query: 236 AGE 238 + E Sbjct: 235 SSE 237 >gi|6912474 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3 [Homo sapiens] Length = 304 Score = 463 bits (1192), Expect = e-130 Identities = 228/281 (81%), Positives = 243/281 (86%) Query: 119 GNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKA 178 G RKPSLLAHPG L+KS ETVILQCWSDVMFEHF LHREG D RL+G+ DGVSKA Sbjct: 24 GFRRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGTFNDTLRLIGEHIDGVSKA 83 Query: 179 NFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGE 238 NFSIG + LAGTYRCYGSVPHSPYQ SAPSDPLDIVITGLYEKPSLSAQPGPTV AGE Sbjct: 84 NFSIGRMRQDLAGTYRCYGSVPHSPYQFSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGE 143 Query: 239 NVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPATHGGTYRCFGSFR 298 +VTLSCSSWSSYD+YHLS EGEAHERR A PKVN TFQADFPLGPAT GGTYRCFGSF Sbjct: 144 SVTLSCSSWSSYDMYHLSTEGEAHERRFSAGPKVNGTFQADFPLGPATQGGTYRCFGSFH 203 Query: 299 ALPCVWSNSSDPLLVSVTGNPSSSWPSPTEPSSKSGICRHLHVLIGTSVVIFLFILLLFF 358 P WS SSDPLLVSVTGNPS+SWPSPTEPSSK+G RHLHVLIGTSVV F +LLFF Sbjct: 204 DSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGNPRHLHVLIGTSVVKLPFTILLFF 263 Query: 359 LLYRWCSNKKNAAVMDQEPAGDRTVNRQDSDEQDPQEVTYA 399 LL+RWCS+KKNA+VMDQ PAG+RTVNR+DSDEQD QEV+YA Sbjct: 264 LLHRWCSDKKNASVMDQGPAGNRTVNREDSDEQDHQEVSYA 304 Score = 163 bits (412), Expect = 3e-40 Identities = 100/238 (42%), Positives = 137/238 (57%), Gaps = 11/238 (4%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 MSL V+SMACVGFF LQGAWP G + KP L A P +V V LQC F +F+L Sbjct: 1 MSLMVISMACVGFFWLQGAWPHEGFRRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60 Query: 61 YKEDRSHVPI-----FHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVI 115 ++E + + + + +F +G + AGTYRC GS PHS +SAPS+PL I Sbjct: 61 HREGTFNDTLRLIGEHIDGVSKANFSIGRMRQDLAGTYRCYGSVPHSPYQFSAPSDPLDI 120 Query: 116 MVTGNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGV 175 ++TG + KPSL A PGP + +GE+V L C S ++ + L EG + + G +G Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSWSSYDMYHLSTEGEAHERRFSAGPKVNGT 180 Query: 176 SKANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPT 233 +A+F +GP GTYRC+GS SPY+ S SDPL + +TG PS ++ P PT Sbjct: 181 FQADFPLGP--ATQGGTYRCFGSFHDSPYEWSKSSDPLLVSVTG---NPS-NSWPSPT 232 >gi|134304835 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5 [Homo sapiens] Length = 304 Score = 461 bits (1187), Expect = e-130 Identities = 229/281 (81%), Positives = 244/281 (86%) Query: 119 GNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKA 178 G RKPSLLAHPGPL+KS ETVILQCWSDVMFEHF LHREG RL+G+ DGVSK Sbjct: 24 GFRRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLLHREGTFNHTLRLIGEHIDGVSKG 83 Query: 179 NFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGE 238 NFSIG + LAGTYRCYGSV HSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTV AGE Sbjct: 84 NFSIGRMTQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGE 143 Query: 239 NVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPATHGGTYRCFGSFR 298 +VTLSCSS SSYD+YHLSREGEAHERRL A PKVNRTFQADFPL PATHGGTYRCFGSFR Sbjct: 144 SVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNRTFQADFPLDPATHGGTYRCFGSFR 203 Query: 299 ALPCVWSNSSDPLLVSVTGNPSSSWPSPTEPSSKSGICRHLHVLIGTSVVIFLFILLLFF 358 P WS SSDPLLVSVTGN S+SWPSPTEPSS++G RHLHVLIGTSVV F +LLFF Sbjct: 204 DSPYEWSKSSDPLLVSVTGNSSNSWPSPTEPSSETGNPRHLHVLIGTSVVKLPFTILLFF 263 Query: 359 LLYRWCSNKKNAAVMDQEPAGDRTVNRQDSDEQDPQEVTYA 399 LL+RWCSNKKNA+VMDQ PAG+RTVNR+DSDEQD QEV+YA Sbjct: 264 LLHRWCSNKKNASVMDQGPAGNRTVNREDSDEQDHQEVSYA 304 Score = 160 bits (406), Expect = 2e-39 Identities = 101/243 (41%), Positives = 137/243 (56%), Gaps = 11/243 (4%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 MSL V+SMACV FFLLQGAWP G + KP L A P +V V LQC F +F+L Sbjct: 1 MSLMVISMACVAFFLLQGAWPHEGFRRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLL 60 Query: 61 YKEDR-SHVPIFHGR----IFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVI 115 ++E +H G + + +F +G +T AGTYRC GS HS SAPS+PL I Sbjct: 61 HREGTFNHTLRLIGEHIDGVSKGNFSIGRMTQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120 Query: 116 MVTGNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGV 175 ++TG + KPSL A PGP + +GE+V L C S ++ + L REG + + G + Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNRT 180 Query: 176 SKANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQ 235 +A+F + P GTYRC+GS SPY+ S SDPL + +TG S ++ P PT Sbjct: 181 FQADFPLDP--ATHGGTYRCFGSFRDSPYEWSKSSDPLLVSVTG----NSSNSWPSPTEP 234 Query: 236 AGE 238 + E Sbjct: 235 SSE 237 >gi|11968154 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A [Homo sapiens] Length = 375 Score = 416 bits (1070), Expect = e-116 Identities = 215/321 (66%), Positives = 247/321 (76%), Gaps = 7/321 (2%) Query: 119 GNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHRE-GISEDPSRLVGQIHDGVSK 177 G KP L A P ++ G V L C S + F F L++E G+ V ++++ + Sbjct: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVP------VPELYNKIFW 77 Query: 178 ANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAG 237 + +GP+ P AGTYRC GS P SP + SAPS+PL IV+TGL+ KPSLSAQPGPTV+ G Sbjct: 78 KSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLFGKPSLSAQPGPTVRTG 137 Query: 238 ENVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPATHGGTYRCFGSF 297 ENVTLSCSS SS+D+YHLSREG AHE RL AVP VN TFQADFPLGPATHGGTY CFGS Sbjct: 138 ENVTLSCSSRSSFDMYHLSREGRAHEPRLPAVPSVNGTFQADFPLGPATHGGTYTCFGSL 197 Query: 298 RALPCVWSNSSDPLLVSVTGNPSSSWPSPTEPSSKSGICRHLHVLIGTSVVIFLFILLLF 357 P WS+ SDPLLVSVTGN SSS SPTEPSSK+GI RHLH+LIGTSV I LFI+L F Sbjct: 198 HDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLHILIGTSVAIILFIILFF 257 Query: 358 FLLYRWCSNKKNAAVMDQEPAGDRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISRPSQR 417 FLL+ CSNKKNAAVMDQEPAGDRTVNR+DSD+QDPQEVTYAQLDHCVF Q KI+ PSQR Sbjct: 258 FLLHCCCSNKKNAAVMDQEPAGDRTVNREDSDDQDPQEVTYAQLDHCVFTQTKITSPSQR 317 Query: 418 PKTPLTDTSVYTELPNAEPRS 438 PKTP TDT++Y ELPNA+PRS Sbjct: 318 PKTPPTDTTMYMELPNAKPRS 338 Score = 246 bits (629), Expect = 2e-65 Identities = 131/233 (56%), Positives = 154/233 (66%), Gaps = 6/233 (2%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 MSL V+SMACVGFFLLQGAW GGQDKP LSA PS VVPRGGHV L C R GF F L Sbjct: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 Query: 61 YKEDRSHVPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGN 120 YKED VP + +IF +S +MGPVTPAHAGTYRCRGS P S WSAPSNPLVI+VTG Sbjct: 61 YKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGL 120 Query: 121 HRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANF 180 KPSL A PGP +++GE V L C S F+ + L REG + +P +G +A+F Sbjct: 121 FGKPSLSAQPGPTVRTGENVTLSCSSRSSFDMYHLSREGRAHEPRLPAVPSVNGTFQADF 180 Query: 181 SIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPT 233 +GP GTY C+GS+ SPY+ S PSDPL + +TG S S+ PT Sbjct: 181 PLGP--ATHGGTYTCFGSLHDSPYEWSDPSDPLLVSVTG----NSSSSSSSPT 227 >gi|124107606 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 isoform a [Homo sapiens] Length = 377 Score = 415 bits (1066), Expect = e-116 Identities = 211/321 (65%), Positives = 244/321 (76%), Gaps = 7/321 (2%) Query: 119 GNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHR-EGISEDPSRLVGQIHDGVSK 177 G KP A P ++ G V L+C F F L++ +G+ V ++++ + Sbjct: 26 GGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTLYKKDGVP------VPELYNRIFW 79 Query: 178 ANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAG 237 +F I P+ P AGTYRC G PHSP + SAPS+PL I++TGLYEKPSL+A+PGPTV+AG Sbjct: 80 NSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGLYEKPSLTARPGPTVRAG 139 Query: 238 ENVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPATHGGTYRCFGSF 297 ENVTLSCSS SS+DIYHLSREGEAHE RL AVP +N TFQADFPLGPATHG TYRCFGSF Sbjct: 140 ENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADFPLGPATHGETYRCFGSF 199 Query: 298 RALPCVWSNSSDPLLVSVTGNPSSSWPSPTEPSSKSGICRHLHVLIGTSVVIFLFILLLF 357 P WS+ SDPL VSVTGNPSSSWPSPTEPS K+GI RHLH +I SV I LF +L F Sbjct: 200 HGSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKTGIARHLHAVIRYSVAIILFTILPF 259 Query: 358 FLLYRWCSNKKNAAVMDQEPAGDRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISRPSQR 417 FLL+RWCS KKNAAVM+QEPAG RTVNR+DSDEQDPQEVTYAQLDHC+F QRKI+ PSQR Sbjct: 260 FLLHRWCSKKKNAAVMNQEPAGHRTVNREDSDEQDPQEVTYAQLDHCIFTQRKITGPSQR 319 Query: 418 PKTPLTDTSVYTELPNAEPRS 438 K P TDTSV ELPNAEPR+ Sbjct: 320 SKRPSTDTSVCIELPNAEPRA 340 Score = 250 bits (638), Expect = 2e-66 Identities = 130/233 (55%), Positives = 157/233 (67%), Gaps = 6/233 (2%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 MS TV+ +AC+GFFL Q W +GGQDKPF SA PS VVP+GGHV L+CHYRRGFN F L Sbjct: 3 MSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTL 62 Query: 61 YKEDRSHVPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGN 120 YK+D VP + RIF SF++ PVTPAHAGTYRCRG PHS T WSAPSNPLVIMVTG Sbjct: 63 YKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGL 122 Query: 121 HRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANF 180 + KPSL A PGP +++GE V L C S F+ + L REG + + +G +A+F Sbjct: 123 YEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADF 182 Query: 181 SIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPT 233 +GP TYRC+GS SPY+ S PSDPL + +TG PS S+ P PT Sbjct: 183 PLGP--ATHGETYRCFGSFHGSPYEWSDPSDPLPVSVTG---NPS-SSWPSPT 229 >gi|66267727 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5B precursor [Homo sapiens] Length = 375 Score = 405 bits (1042), Expect = e-113 Identities = 210/321 (65%), Positives = 243/321 (75%), Gaps = 7/321 (2%) Query: 119 GNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHRE-GISEDPSRLVGQIHDGVSK 177 G KP L A P ++ G V L C S + F F L++E G+ V ++++ + Sbjct: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVP------VPELYNKIFW 77 Query: 178 ANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAG 237 + +GP+ P AGTYRC GS P SP + SAPS+PL IV+TGL+ KPSLSAQPGPTV+ G Sbjct: 78 KSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLFGKPSLSAQPGPTVRTG 137 Query: 238 ENVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPATHGGTYRCFGSF 297 ENV LSCSS SS+D+YHLSREG AHE RL AVP V+ TFQADFPLGPATHGGTY CF S Sbjct: 138 ENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADFPLGPATHGGTYTCFSSL 197 Query: 298 RALPCVWSNSSDPLLVSVTGNPSSSWPSPTEPSSKSGICRHLHVLIGTSVVIFLFILLLF 357 P WS+ SDPLLVSVTGN SSS SPTEPSSK+GI RHLH+LIGTSV I LFI+L F Sbjct: 198 HDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLHILIGTSVAIILFIILFF 257 Query: 358 FLLYRWCSNKKNAAVMDQEPAGDRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISRPSQR 417 FLL+ CSNKKNAAVMDQ PAGDRTVNR+DSD+QDPQEVTYAQLDHCVF Q KI+ PSQR Sbjct: 258 FLLHCCCSNKKNAAVMDQGPAGDRTVNREDSDDQDPQEVTYAQLDHCVFTQTKITSPSQR 317 Query: 418 PKTPLTDTSVYTELPNAEPRS 438 PK P TDT++Y ELPNA+PRS Sbjct: 318 PKAPPTDTTMYMELPNAKPRS 338 Score = 246 bits (628), Expect = 3e-65 Identities = 131/233 (56%), Positives = 153/233 (65%), Gaps = 6/233 (2%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 MSL V+SMACVGFFLLQGAW GGQDKP LSA PS VVPRGGHV L C R GF F L Sbjct: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60 Query: 61 YKEDRSHVPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGN 120 YKED VP + +IF +S +MGPVTPAHAGTYRCRGS P S WSAPSNPLVI+VTG Sbjct: 61 YKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGL 120 Query: 121 HRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANF 180 KPSL A PGP +++GE V L C S F+ + L REG + +P DG +A+F Sbjct: 121 FGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADF 180 Query: 181 SIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPT 233 +GP GTY C+ S+ SPY+ S PSDPL + +TG S S+ PT Sbjct: 181 PLGP--ATHGGTYTCFSSLHDSPYEWSDPSDPLLVSVTG----NSSSSSSSPT 227 >gi|124107610 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 isoform c [Homo sapiens] Length = 342 Score = 348 bits (894), Expect = 4e-96 Identities = 187/321 (58%), Positives = 218/321 (67%), Gaps = 42/321 (13%) Query: 119 GNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHR-EGISEDPSRLVGQIHDGVSK 177 G KP A P ++ G V L+C F F L++ +G+ V ++++ + Sbjct: 26 GGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTLYKKDGVP------VPELYNRIFW 79 Query: 178 ANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAG 237 +F I P+ P AGTYRC G PHSP + SAPS+PL I++TGLYEKPSL+A+PGPTV+AG Sbjct: 80 NSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGLYEKPSLTARPGPTVRAG 139 Query: 238 ENVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPATHGGTYRCFGSF 297 ENVTLSCSS SS+DIYHLSREGEAHE RL AVP +N TFQADFPLGPATHG TYRCFGSF Sbjct: 140 ENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADFPLGPATHGETYRCFGSF 199 Query: 298 RALPCVWSNSSDPLLVSVTGNPSSSWPSPTEPSSKSGICRHLHVLIGTSVVIFLFILLLF 357 P WS+ SDPL VSVTGNPSSSWPSPTEPS K+ Sbjct: 200 HGSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKT------------------------ 235 Query: 358 FLLYRWCSNKKNAAVMDQEPAGDRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISRPSQR 417 +AAVM+QEPAG RTVNR+DSDEQDPQEVTYAQLDHC+F QRKI+ PSQR Sbjct: 236 -----------DAAVMNQEPAGHRTVNREDSDEQDPQEVTYAQLDHCIFTQRKITGPSQR 284 Query: 418 PKTPLTDTSVYTELPNAEPRS 438 K P TDTSV ELPNAEPR+ Sbjct: 285 SKRPSTDTSVCIELPNAEPRA 305 Score = 250 bits (638), Expect = 2e-66 Identities = 130/233 (55%), Positives = 157/233 (67%), Gaps = 6/233 (2%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 MS TV+ +AC+GFFL Q W +GGQDKPF SA PS VVP+GGHV L+CHYRRGFN F L Sbjct: 3 MSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTL 62 Query: 61 YKEDRSHVPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGN 120 YK+D VP + RIF SF++ PVTPAHAGTYRCRG PHS T WSAPSNPLVIMVTG Sbjct: 63 YKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGL 122 Query: 121 HRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANF 180 + KPSL A PGP +++GE V L C S F+ + L REG + + +G +A+F Sbjct: 123 YEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADF 182 Query: 181 SIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPT 233 +GP TYRC+GS SPY+ S PSDPL + +TG PS S+ P PT Sbjct: 183 PLGP--ATHGETYRCFGSFHGSPYEWSDPSDPLPVSVTG---NPS-SSWPSPT 229 >gi|124107604 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 isoform b [Homo sapiens] Length = 273 Score = 300 bits (768), Expect = 2e-81 Identities = 154/251 (61%), Positives = 182/251 (72%), Gaps = 7/251 (2%) Query: 119 GNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHR-EGISEDPSRLVGQIHDGVSK 177 G KP A P ++ G V L+C F F L++ +G+ V ++++ + Sbjct: 26 GGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTLYKKDGVP------VPELYNRIFW 79 Query: 178 ANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAG 237 +F I P+ P AGTYRC G PHSP + SAPS+PL I++TGLYEKPSL+A+PGPTV+AG Sbjct: 80 NSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGLYEKPSLTARPGPTVRAG 139 Query: 238 ENVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPATHGGTYRCFGSF 297 ENVTLSCSS SS+DIYHLSREGEAHE RL AVP +N TFQADFPLGPATHG TYRCFGSF Sbjct: 140 ENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADFPLGPATHGETYRCFGSF 199 Query: 298 RALPCVWSNSSDPLLVSVTGNPSSSWPSPTEPSSKSGICRHLHVLIGTSVVIFLFILLLF 357 P WS+ SDPL VSVTGNPSSSWPSPTEPS K+GI RHLH +I SV I LF +L F Sbjct: 200 HGSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKTGIARHLHAVIRYSVAIILFTILPF 259 Query: 358 FLLYRWCSNKK 368 FLL+RWCS KK Sbjct: 260 FLLHRWCSKKK 270 Score = 250 bits (638), Expect = 2e-66 Identities = 130/233 (55%), Positives = 157/233 (67%), Gaps = 6/233 (2%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 MS TV+ +AC+GFFL Q W +GGQDKPF SA PS VVP+GGHV L+CHYRRGFN F L Sbjct: 3 MSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTL 62 Query: 61 YKEDRSHVPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGN 120 YK+D VP + RIF SF++ PVTPAHAGTYRCRG PHS T WSAPSNPLVIMVTG Sbjct: 63 YKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGL 122 Query: 121 HRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANF 180 + KPSL A PGP +++GE V L C S F+ + L REG + + +G +A+F Sbjct: 123 YEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADF 182 Query: 181 SIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPT 233 +GP TYRC+GS SPY+ S PSDPL + +TG PS S+ P PT Sbjct: 183 PLGP--ATHGETYRCFGSFHGSPYEWSDPSDPLPVSVTG---NPS-SSWPSPT 229 >gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B, member 3 isoform 2 [Homo sapiens] Length = 631 Score = 289 bits (739), Expect = 4e-78 Identities = 181/456 (39%), Positives = 256/456 (56%), Gaps = 28/456 (6%) Query: 22 LMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFMLYKEDRSHVPI------FHGRI 75 + G KP LSA PS VV GG++ L+C ++G+++F+L KE +P H R Sbjct: 117 MTGAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRG 176 Query: 76 FQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGNHRKPSLLAHPGPLLK 135 FQ F +GPVTP+H + C ++ WS PS+PL I+ +G RKPSLL GP+L Sbjct: 177 FQALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLA 236 Query: 136 SGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANFSIGPLMPVLAGTYRC 195 G+++ LQC SDV + F L++EG + R Q G+S+ANF++GP+ P G YRC Sbjct: 237 PGQSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRC 296 Query: 196 YGSVPHSPYQLSAPSDPLDIVITG-LYEKPSLSAQPGPTVQAGENVTLSCSSWSSYDIYH 254 YG+ S + SAPSDPL+I++ G +Y+ SLSAQPGPTV +GENVTL C SW +D + Sbjct: 297 YGAHNLSS-EWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFL 355 Query: 255 LSREGEAH-ERRLRAVPKVNRTFQADFPLGPAT--HGGTYRCFGSFRALPCVWSNSSDPL 311 L++EG AH RLR++ ++ +QA+FP+ P T H GTYRC+GS+ + P + S+ S+PL Sbjct: 356 LTKEGAAHPPLRLRSMYGAHK-YQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPL 414 Query: 312 LVSVTGNPSSSWPSPTEPSSKSGICRHLHVLIGTSVVIFLFILLLFFLLYRWCSNKKNAA 371 + V+G+ S PT P S G+ R+L VLIG SV L + LL FLL R + K+ Sbjct: 415 ELVVSGHSGGSSLPPTGPPSTPGLGRYLEVLIGVSVAFVLLLFLLLFLLLRRQRHSKHRT 474 Query: 372 VMD-----QEPAG-------DRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISRPSQRPK 419 Q PAG DR + R+ S D QE + ++ SQ P Sbjct: 475 SDQRKTDFQRPAGAAETEPKDRGLLRRSSPAADVQEENLYAAVKDTQSEDRVELDSQSPH 534 Query: 420 TPLTDTSVYTELPNAEPRSKVVSCPRAPQSGLEGVF 455 Y + ++ PR ++ S P S L G F Sbjct: 535 DEDPQAVTYAPVKHSSPRREMAS----PPSSLSGEF 566 Score = 169 bits (428), Expect = 5e-42 Identities = 114/345 (33%), Positives = 173/345 (50%), Gaps = 17/345 (4%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 M+ + ++ C+G L G KP L A P +V+ G V + C + + L Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRL 60 Query: 61 YKEDRSHVPIFHGRIFQES----FIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIM 116 +KE S P+ + F + +T HAG YRC +S GWS PS+PL ++ Sbjct: 61 HKEG-SPEPLDRNNPLEPKNKARFSIPSMTEHHAGRYRCHY---YSSAGWSEPSDPLEMV 116 Query: 117 VTGNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVG-QIHDGV 175 +TG + KP+L A P P++ SG + L+C S + HF L +EG + P L Q+H Sbjct: 117 MTGAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRG 176 Query: 176 SKANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQ 235 +A F +GP+ P + CY ++P+ S PSDPL+I+ +G+ KPSL GP + Sbjct: 177 FQALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLA 236 Query: 236 AGENVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPA--THGGTYRC 293 G+++TL C S Y+ + L +EGE + QA+F LGP ++GG YRC Sbjct: 237 PGQSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRC 296 Query: 294 FGSFRALPCVWSNSSDPLLVSVTGN-----PSSSWPSPTEPSSKS 333 +G+ L WS SDPL + + G S+ P PT S ++ Sbjct: 297 YGAHN-LSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGEN 340 Score = 31.6 bits (70), Expect = 1.6 Identities = 20/60 (33%), Positives = 35/60 (58%), Gaps = 4/60 (6%) Query: 374 DQEPAGDRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISR--PSQRPKTPLTDTSVYTEL 431 D++ DR ++ + + + Q+VTYAQL H + ++RK + PSQ + P + S+Y L Sbjct: 571 DRQVEEDRQMDTEAAASEASQDVTYAQL-HSLTLRRKATEPPPSQEGEPP-AEPSIYATL 628 >gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B, member 3 isoform 1 [Homo sapiens] Length = 632 Score = 287 bits (734), Expect = 2e-77 Identities = 183/457 (40%), Positives = 256/457 (56%), Gaps = 29/457 (6%) Query: 22 LMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFMLYKEDRSHVPI------FHGRI 75 + G KP LSA PS VV GG++ L+C ++G+++F+L KE +P H R Sbjct: 117 MTGAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRG 176 Query: 76 FQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGNHRKPSLLAHPGPLLK 135 FQ F +GPVTP+H + C ++ WS PS+PL I+ +G RKPSLL GP+L Sbjct: 177 FQALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLA 236 Query: 136 SGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANFSIGPLMPVLAGTYRC 195 G+++ LQC SDV + F L++EG + R Q G+S+ANF++GP+ P G YRC Sbjct: 237 PGQSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRC 296 Query: 196 YGSVPHSPYQLSAPSDPLDIVITG-LYEKPSLSAQPGPTVQAGENVTLSCSSWSSYDIYH 254 YG+ S + SAPSDPL+I++ G +Y+ SLSAQPGPTV +GENVTL C SW +D + Sbjct: 297 YGAHNLSS-EWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFL 355 Query: 255 LSREGEAH-ERRLRAVPKVNRTFQADFPLGPAT--HGGTYRCFGSFRALPCVWSNSSDPL 311 L++EG AH RLR++ ++ +QA+FP+ P T H GTYRC+GS+ + P + S+ S+PL Sbjct: 356 LTKEGAAHPPLRLRSMYGAHK-YQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPL 414 Query: 312 LVSVTGNPSSSWPSPTEPSSKSGICRHLHVLIGTSVVIFLFILLLFFLLYRWCSNKKNAA 371 + V+G+ S PT P S G+ R+L VLIG SV L + LL FLL R + K+ Sbjct: 415 ELVVSGHSGGSSLPPTGPPSTPGLGRYLEVLIGVSVAFVLLLFLLLFLLLRRQRHSKHRT 474 Query: 372 VMD-----QEPAG-------DRTVNRQDSDEQDPQEVT-YAQLDHCVFIQRKISRPSQRP 418 Q PAG DR + R+ S D QE YA + R Q P Sbjct: 475 SDQRKTDFQRPAGAAETEPKDRGLLRRSSPAADVQEENLYAAVKDTQSEDRVELDSQQSP 534 Query: 419 KTPLTDTSVYTELPNAEPRSKVVSCPRAPQSGLEGVF 455 Y + ++ PR ++ S P S L G F Sbjct: 535 HDEDPQAVTYAPVKHSSPRREMAS----PPSSLSGEF 567 Score = 169 bits (428), Expect = 5e-42 Identities = 114/345 (33%), Positives = 173/345 (50%), Gaps = 17/345 (4%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 M+ + ++ C+G L G KP L A P +V+ G V + C + + L Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRL 60 Query: 61 YKEDRSHVPIFHGRIFQES----FIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIM 116 +KE S P+ + F + +T HAG YRC +S GWS PS+PL ++ Sbjct: 61 HKEG-SPEPLDRNNPLEPKNKARFSIPSMTEHHAGRYRCHY---YSSAGWSEPSDPLEMV 116 Query: 117 VTGNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVG-QIHDGV 175 +TG + KP+L A P P++ SG + L+C S + HF L +EG + P L Q+H Sbjct: 117 MTGAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRG 176 Query: 176 SKANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQ 235 +A F +GP+ P + CY ++P+ S PSDPL+I+ +G+ KPSL GP + Sbjct: 177 FQALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLA 236 Query: 236 AGENVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPA--THGGTYRC 293 G+++TL C S Y+ + L +EGE + QA+F LGP ++GG YRC Sbjct: 237 PGQSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRC 296 Query: 294 FGSFRALPCVWSNSSDPLLVSVTGN-----PSSSWPSPTEPSSKS 333 +G+ L WS SDPL + + G S+ P PT S ++ Sbjct: 297 YGAHN-LSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGEN 340 Score = 31.6 bits (70), Expect = 1.6 Identities = 20/60 (33%), Positives = 35/60 (58%), Gaps = 4/60 (6%) Query: 374 DQEPAGDRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISR--PSQRPKTPLTDTSVYTEL 431 D++ DR ++ + + + Q+VTYAQL H + ++RK + PSQ + P + S+Y L Sbjct: 572 DRQVEEDRQMDTEAAASEASQDVTYAQL-HSLTLRRKATEPPPSQEGEPP-AEPSIYATL 629 >gi|71143143 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 isoform 1 [Homo sapiens] Length = 243 Score = 278 bits (712), Expect = 6e-75 Identities = 144/220 (65%), Positives = 165/220 (75%), Gaps = 2/220 (0%) Query: 219 GLYEKPSLSAQPGPTVQAGENVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQA 278 G++ KPSL A PGP V++ E V L C S + + L REG+ + + +A Sbjct: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 Query: 279 DFPLGPATH--GGTYRCFGSFRALPCVWSNSSDPLLVSVTGNPSSSWPSPTEPSSKSGIC 336 +F +GP GTYRC+GS P S SDPLLVSVTGNPS+SWPSPTEPSS++G Sbjct: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNP 143 Query: 337 RHLHVLIGTSVVIFLFILLLFFLLYRWCSNKKNAAVMDQEPAGDRTVNRQDSDEQDPQEV 396 RHLHVLIGTSVVI LFILLLFFLL+RWC NKKNA VMDQEPAG+RTVNR+DSDEQDPQEV Sbjct: 144 RHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEV 203 Query: 397 TYAQLDHCVFIQRKISRPSQRPKTPLTDTSVYTELPNAEP 436 TYAQL+HCVF QRKI+RPSQRPKTP TD VYTELPNAEP Sbjct: 204 TYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAEP 243 Score = 169 bits (427), Expect = 6e-42 Identities = 84/120 (70%), Positives = 95/120 (79%), Gaps = 4/120 (3%) Query: 119 GNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKA 178 G HRKPSLLAHPGPL+KS ETVILQCWSDV F+HF LHREG +D L+G+ HDGVSKA Sbjct: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83 Query: 179 NFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGE 238 NFSIGP+M LAGTYRCYGSV HSPYQLSAPSDPL + +TG PS ++ P PT + E Sbjct: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTG---NPS-NSWPSPTEPSSE 139 Score = 103 bits (256), Expect = 4e-22 Identities = 67/144 (46%), Positives = 82/144 (56%), Gaps = 9/144 (6%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 MSL VVSM CVGFFLLQGAWP G KP L A P +V V LQC F +F+L Sbjct: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60 Query: 61 YKE----DRSH-VPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVI 115 ++E D H + H + + +F +GP+ AGTYRC GS HS SAPS+PL++ Sbjct: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120 Query: 116 MVTGNHRKPSLLAHPGPLLKSGET 139 VTGN PS + P P S ET Sbjct: 121 SVTGN---PS-NSWPSPTEPSSET 140 >gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B, member 2 isoform 2 [Homo sapiens] Length = 597 Score = 261 bits (667), Expect = 9e-70 Identities = 179/482 (37%), Positives = 256/482 (53%), Gaps = 76/482 (15%) Query: 22 LMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFMLYKEDRSHVPIF-----HGRIF 76 + G KP LSA+PS VV GG V LQC + F F+L KE P H R Sbjct: 117 MTGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGS 176 Query: 77 QES-FIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGNHRKPSLLAHPGPLLK 135 + F +GPV+P ++RC G +S WS+PS+ L ++V G +KPSL PGP++ Sbjct: 177 SRAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVA 236 Query: 136 SGETVILQCWSDVMFEHFFLHREGISEDPSRLVG-QIHDGVSKANFSIGPLMPVLAGTYR 194 GE++ LQC SDV ++ F L++EG D +L G Q G+S+ANF++GP+ G YR Sbjct: 237 PGESLTLQCVSDVGYDRFVLYKEG-ERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYR 295 Query: 195 CYGSVPHSPYQLSAPSDPLDIVITG-LYEKPSLSAQPGPTVQAGENVTLSCSSWSSYDIY 253 CYG+ S + SAPSDPLDI+ITG + P +S QPGPTV +GENVTL C SW + + Sbjct: 296 CYGAHNLSS-ECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTF 354 Query: 254 HLSREGEAH-ERRLRAVPKVNRTFQADFPLGPAT--HGGTYRCFGSFRALPCVWSNSSDP 310 L++ G A RLR++ + + +QA+FP+ P T H GTYRC+GS + P + S+ S+P Sbjct: 355 LLTKAGAADAPLRLRSIHEYPK-YQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEP 413 Query: 311 LLVSVTGNPSSSWPSPTEPSS----------------KSGICRHLHVLIG--TSVVIFLF 352 L + V+G S P PT P S +SG+ RHL V+IG +VV+ L Sbjct: 414 LELVVSGPSMGSSPPPTGPISTPGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVVLLLL 473 Query: 353 ILLLFFLLYR-------WCSNKKN-----------------------------------A 370 +LLL FL+ R W S ++ A Sbjct: 474 LLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGLQWRSSPAADAQEENLYA 533 Query: 371 AVMDQEPAGDRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISR-PSQRPKTPLTDTSVYT 429 AV D +P ++ + + + PQ+VTYAQL H + ++RK + P + + P + S+Y Sbjct: 534 AVKDTQPEDGVEMDTRAAASEAPQDVTYAQL-HSLTLRRKATEPPPSQEREPPAEPSIYA 592 Query: 430 EL 431 L Sbjct: 593 TL 594 Score = 195 bits (495), Expect = 8e-50 Identities = 131/344 (38%), Positives = 181/344 (52%), Gaps = 15/344 (4%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 M+ V + C+G L G KP L A P +V+ +G V L C + L Sbjct: 1 MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRL 60 Query: 61 YKEDRSHVPIFHGR---IFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMV 117 Y+E +S I R + F + +T H G Y C+ +S WS S+PLV+++ Sbjct: 61 YREKKSASWITRIRPELVKNGQFHIPSITWEHTGRYGCQY---YSRARWSELSDPLVLVM 117 Query: 118 TGNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHD-GVS 176 TG + KP+L A P P++ SG V LQC S V F F L +EG E P L Q H G S Sbjct: 118 TGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSS 177 Query: 177 KANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQA 236 +A FS+GP+ P ++RCYG +SPY S+PSD L++++ G+ +KPSLS QPGP V Sbjct: 178 RAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAP 237 Query: 237 GENVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPA--THGGTYRCF 294 GE++TL C S YD + L +EGE R+L QA+F LGP ++GG YRC+ Sbjct: 238 GESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCY 297 Query: 295 GSFRALPCVWSNSSDPLLVSVTGNPS-----SSWPSPTEPSSKS 333 G+ L S SDPL + +TG S P PT S ++ Sbjct: 298 GAHN-LSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGEN 340 >gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B, member 2 isoform 1 [Homo sapiens] Length = 598 Score = 261 bits (666), Expect = 1e-69 Identities = 179/483 (37%), Positives = 256/483 (53%), Gaps = 77/483 (15%) Query: 22 LMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFMLYKEDRSHVPIF-----HGRIF 76 + G KP LSA+PS VV GG V LQC + F F+L KE P H R Sbjct: 117 MTGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGS 176 Query: 77 QES-FIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGNHRKPSLLAHPGPLLK 135 + F +GPV+P ++RC G +S WS+PS+ L ++V G +KPSL PGP++ Sbjct: 177 SRAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVA 236 Query: 136 SGETVILQCWSDVMFEHFFLHREGISEDPSRLVG-QIHDGVSKANFSIGPLMPVLAGTYR 194 GE++ LQC SDV ++ F L++EG D +L G Q G+S+ANF++GP+ G YR Sbjct: 237 PGESLTLQCVSDVGYDRFVLYKEG-ERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYR 295 Query: 195 CYGSVPHSPYQLSAPSDPLDIVITG-LYEKPSLSAQPGPTVQAGENVTLSCSSWSSYDIY 253 CYG+ S + SAPSDPLDI+ITG + P +S QPGPTV +GENVTL C SW + + Sbjct: 296 CYGAHNLSS-ECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTF 354 Query: 254 HLSREGEAH-ERRLRAVPKVNRTFQADFPLGPAT--HGGTYRCFGSFRALPCVWSNSSDP 310 L++ G A RLR++ + + +QA+FP+ P T H GTYRC+GS + P + S+ S+P Sbjct: 355 LLTKAGAADAPLRLRSIHEYPK-YQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEP 413 Query: 311 LLVSVTGNPSSSWPSPTEPSS-----------------KSGICRHLHVLIG--TSVVIFL 351 L + V+G S P PT P S +SG+ RHL V+IG +VV+ L Sbjct: 414 LELVVSGPSMGSSPPPTGPISTPAGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVVLLL 473 Query: 352 FILLLFFLLYR-------WCSNKKN----------------------------------- 369 +LLL FL+ R W S ++ Sbjct: 474 LLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGLQWRSSPAADAQEENLY 533 Query: 370 AAVMDQEPAGDRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISR-PSQRPKTPLTDTSVY 428 AAV D +P ++ + + + PQ+VTYAQL H + ++RK + P + + P + S+Y Sbjct: 534 AAVKDTQPEDGVEMDTRAAASEAPQDVTYAQL-HSLTLRRKATEPPPSQEREPPAEPSIY 592 Query: 429 TEL 431 L Sbjct: 593 ATL 595 Score = 195 bits (495), Expect = 8e-50 Identities = 131/344 (38%), Positives = 181/344 (52%), Gaps = 15/344 (4%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 M+ V + C+G L G KP L A P +V+ +G V L C + L Sbjct: 1 MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRL 60 Query: 61 YKEDRSHVPIFHGR---IFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMV 117 Y+E +S I R + F + +T H G Y C+ +S WS S+PLV+++ Sbjct: 61 YREKKSASWITRIRPELVKNGQFHIPSITWEHTGRYGCQY---YSRARWSELSDPLVLVM 117 Query: 118 TGNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHD-GVS 176 TG + KP+L A P P++ SG V LQC S V F F L +EG E P L Q H G S Sbjct: 118 TGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSS 177 Query: 177 KANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQA 236 +A FS+GP+ P ++RCYG +SPY S+PSD L++++ G+ +KPSLS QPGP V Sbjct: 178 RAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAP 237 Query: 237 GENVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPA--THGGTYRCF 294 GE++TL C S YD + L +EGE R+L QA+F LGP ++GG YRC+ Sbjct: 238 GESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCY 297 Query: 295 GSFRALPCVWSNSSDPLLVSVTGNPS-----SSWPSPTEPSSKS 333 G+ L S SDPL + +TG S P PT S ++ Sbjct: 298 GAHN-LSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGEN 340 >gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B, member 1 isoform 4 [Homo sapiens] Length = 651 Score = 252 bits (644), Expect = 4e-67 Identities = 182/471 (38%), Positives = 251/471 (53%), Gaps = 50/471 (10%) Query: 24 GGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFMLYKEDRSHVPIF-----HGRIFQE 78 G KP LSA+PS VV GG+V LQC + F+ F L KE P H R Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179 Query: 79 S-FIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGNHRKPSLLAHPGPLLKSG 137 + F +GPV+P+ YRC +S WS PS+ L ++V G +KPSL PGP++ Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239 Query: 138 ETVILQCWSDVMFEHFFLHREGISEDPSRLVG-QIHDGVSKANFSIGPLMPVLAGTYRCY 196 ET+ LQC SD + F L+++G D +L G Q G+S+ANF++GP+ G YRCY Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDG-ERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCY 298 Query: 197 GSVPHSPYQLSAPSDPLDIVITG-LYEKPSLSAQPGPTVQAGENVTLSCSSWSSYDIYHL 255 G+ S + SAPSDPLDI+I G Y++ SLS QPGPTV +GENVTL C S + L Sbjct: 299 GAHNLSS-EWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLL 357 Query: 256 SREGEAHER-RLRAVPKVNRTFQADFPLGPAT--HGGTYRCFGSFRALPCVWSNSSDPLL 312 ++EG A + RLR+ + ++ +QA+FP+GP T H GTYRC+GS + P + ++ SDPL Sbjct: 358 TKEGAADDPWRLRSTYQ-SQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLE 416 Query: 313 VSV---TGNPSSSWPSPTEPSS-------------KSGICRHLHVLIG--TSVVIFLFIL 354 + V +G PSS PT S +SG+ RHL V+IG +V++ L +L Sbjct: 417 LVVSGPSGGPSSPTTGPTSTSGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVILLLLLL 476 Query: 355 LLFFLLYR-------WCSNKKNAAVMDQEPAG-------DRTVNRQDSDEQDPQEVT-YA 399 LL FL+ R W S ++ A Q PAG DR + + S D QE YA Sbjct: 477 LLLFLILRHRRQGKHWTSTQRKADF--QHPAGAVGPEPTDRGLQWRSSPAADAQEENLYA 534 Query: 400 QLDHCVFIQRKISRPSQRPKTPLTDTSVYTELPNAEPRSKVVSCPRAPQSG 450 + H Q P Y E+ ++ PR ++ S P +P SG Sbjct: 535 AVKHTQPEDGVEMDTRQSPHDEDPQAVTYAEVKHSRPRREMAS-PPSPLSG 584 Score = 195 bits (495), Expect = 8e-50 Identities = 132/347 (38%), Positives = 184/347 (53%), Gaps = 20/347 (5%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 M+ + + C+G L G KP L A P +V+ +G V L+C + + L Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60 Query: 61 YKEDRSHVPIFHGRIFQE-----SFIMGPVTPAHAGTYRCR-GSRPHSLTGWSAPSNPLV 114 Y+E ++ + I RI QE F + +T HAG YRC GS G S S+PL Sbjct: 61 YREKKTALWIT--RIPQELVKKGQFPIPSITWEHAGRYRCYYGS---DTAGRSESSDPLE 115 Query: 115 IMVTGNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIH-D 173 ++VTG + KP+L A P P++ SG VILQC S V F+ F L +EG E P L Q H Sbjct: 116 LVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHAR 175 Query: 174 GVSKANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPT 233 G S+A FS+GP+ P YRCY +SPY+ S PSD L++++ G+ +KPSLS QPGP Sbjct: 176 GSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPI 235 Query: 234 VQAGENVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPA--THGGTY 291 V E +TL C S + Y+ + L ++GE +L QA+F LGP ++GG Y Sbjct: 236 VAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQY 295 Query: 292 RCFGSFRALPCVWSNSSDPLLVSVTGN-----PSSSWPSPTEPSSKS 333 RC+G+ L WS SDPL + + G S P PT S ++ Sbjct: 296 RCYGAHN-LSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGEN 341 Score = 32.3 bits (72), Expect = 0.91 Identities = 20/60 (33%), Positives = 35/60 (58%), Gaps = 4/60 (6%) Query: 374 DQEPAGDRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISR--PSQRPKTPLTDTSVYTEL 431 D++ DR ++ + + + PQ+VTYAQL H + ++R+ + PSQ +P S+Y L Sbjct: 591 DRQAEEDRQMDTEAAASEAPQDVTYAQL-HSLTLRREATEPPPSQEGPSPAV-PSIYATL 648 >gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B, member 1 isoform 3 [Homo sapiens] Length = 651 Score = 252 bits (644), Expect = 4e-67 Identities = 181/472 (38%), Positives = 255/472 (54%), Gaps = 52/472 (11%) Query: 24 GGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFMLYKEDRSHVPIF-----HGRIFQE 78 G KP LSA+PS VV GG+V LQC + F+ F L KE P H R Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179 Query: 79 S-FIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGNHRKPSLLAHPGPLLKSG 137 + F +GPV+P+ YRC +S WS PS+ L ++V G +KPSL PGP++ Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239 Query: 138 ETVILQCWSDVMFEHFFLHREGISEDPSRLVG-QIHDGVSKANFSIGPLMPVLAGTYRCY 196 ET+ LQC SD + F L+++G D +L G Q G+S+ANF++GP+ G YRCY Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDG-ERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCY 298 Query: 197 GSVPHSPYQLSAPSDPLDIVITG-LYEKPSLSAQPGPTVQAGENVTLSCSSWSSYDIYHL 255 G+ S + SAPSDPLDI+I G Y++ SLS QPGPTV +GENVTL C S + L Sbjct: 299 GAHNLSS-EWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLL 357 Query: 256 SREGEAHER-RLRAVPKVNRTFQADFPLGPAT--HGGTYRCFGSFRALPCVWSNSSDPLL 312 ++EG A + RLR+ + ++ +QA+FP+GP T H GTYRC+GS + P + ++ SDPL Sbjct: 358 TKEGAADDPWRLRSTYQ-SQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLE 416 Query: 313 VSV---TGNPSSSWPSPTEPSS--------------KSGICRHLHVLIG--TSVVIFLFI 353 + V +G PSS PT S+ +SG+ RHL V+IG +V++ L + Sbjct: 417 LVVSGPSGGPSSPTTGPTSTSAGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVILLLLL 476 Query: 354 LLLFFLLYR-------WCSNKKNAAVMDQEPAG-------DRTVNRQDSDEQDPQEVT-Y 398 LLL FL+ R W S ++ A Q PAG DR + + S D QE Y Sbjct: 477 LLLLFLILRHRRQGKHWTSTQRKADF--QHPAGAVGPEPTDRGLQWRSSPAADAQEENLY 534 Query: 399 AQLDHCVFIQRKISRPSQRPKTPLTDTSVYTELPNAEPRSKVVSCPRAPQSG 450 A + H + + ++ P Y E+ ++ PR ++ S P +P SG Sbjct: 535 AAVKH-TQPEDGVEMDTRSPHDEDPQAVTYAEVKHSRPRREMAS-PPSPLSG 584 Score = 195 bits (495), Expect = 8e-50 Identities = 132/347 (38%), Positives = 184/347 (53%), Gaps = 20/347 (5%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 M+ + + C+G L G KP L A P +V+ +G V L+C + + L Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60 Query: 61 YKEDRSHVPIFHGRIFQE-----SFIMGPVTPAHAGTYRCR-GSRPHSLTGWSAPSNPLV 114 Y+E ++ + I RI QE F + +T HAG YRC GS G S S+PL Sbjct: 61 YREKKTALWIT--RIPQELVKKGQFPIPSITWEHAGRYRCYYGS---DTAGRSESSDPLE 115 Query: 115 IMVTGNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIH-D 173 ++VTG + KP+L A P P++ SG VILQC S V F+ F L +EG E P L Q H Sbjct: 116 LVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHAR 175 Query: 174 GVSKANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPT 233 G S+A FS+GP+ P YRCY +SPY+ S PSD L++++ G+ +KPSLS QPGP Sbjct: 176 GSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPI 235 Query: 234 VQAGENVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPA--THGGTY 291 V E +TL C S + Y+ + L ++GE +L QA+F LGP ++GG Y Sbjct: 236 VAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQY 295 Query: 292 RCFGSFRALPCVWSNSSDPLLVSVTGN-----PSSSWPSPTEPSSKS 333 RC+G+ L WS SDPL + + G S P PT S ++ Sbjct: 296 RCYGAHN-LSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGEN 341 Score = 32.3 bits (72), Expect = 0.91 Identities = 20/60 (33%), Positives = 35/60 (58%), Gaps = 4/60 (6%) Query: 374 DQEPAGDRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISR--PSQRPKTPLTDTSVYTEL 431 D++ DR ++ + + + PQ+VTYAQL H + ++R+ + PSQ +P S+Y L Sbjct: 591 DRQAEEDRQMDTEAAASEAPQDVTYAQL-HSLTLRREATEPPPSQEGPSPAV-PSIYATL 648 >gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B, member 1 isoform 2 [Homo sapiens] Length = 652 Score = 252 bits (644), Expect = 4e-67 Identities = 182/472 (38%), Positives = 252/472 (53%), Gaps = 51/472 (10%) Query: 24 GGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFMLYKEDRSHVPIF-----HGRIFQE 78 G KP LSA+PS VV GG+V LQC + F+ F L KE P H R Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179 Query: 79 S-FIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGNHRKPSLLAHPGPLLKSG 137 + F +GPV+P+ YRC +S WS PS+ L ++V G +KPSL PGP++ Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239 Query: 138 ETVILQCWSDVMFEHFFLHREGISEDPSRLVG-QIHDGVSKANFSIGPLMPVLAGTYRCY 196 ET+ LQC SD + F L+++G D +L G Q G+S+ANF++GP+ G YRCY Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDG-ERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCY 298 Query: 197 GSVPHSPYQLSAPSDPLDIVITG-LYEKPSLSAQPGPTVQAGENVTLSCSSWSSYDIYHL 255 G+ S + SAPSDPLDI+I G Y++ SLS QPGPTV +GENVTL C S + L Sbjct: 299 GAHNLSS-EWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLL 357 Query: 256 SREGEAHER-RLRAVPKVNRTFQADFPLGPAT--HGGTYRCFGSFRALPCVWSNSSDPLL 312 ++EG A + RLR+ + ++ +QA+FP+GP T H GTYRC+GS + P + ++ SDPL Sbjct: 358 TKEGAADDPWRLRSTYQ-SQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLE 416 Query: 313 VSV---TGNPSSSWPSPTEPSS--------------KSGICRHLHVLIG--TSVVIFLFI 353 + V +G PSS PT S+ +SG+ RHL V+IG +V++ L + Sbjct: 417 LVVSGPSGGPSSPTTGPTSTSAGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVILLLLL 476 Query: 354 LLLFFLLYR-------WCSNKKNAAVMDQEPAG-------DRTVNRQDSDEQDPQEVT-Y 398 LLL FL+ R W S ++ A Q PAG DR + + S D QE Y Sbjct: 477 LLLLFLILRHRRQGKHWTSTQRKADF--QHPAGAVGPEPTDRGLQWRSSPAADAQEENLY 534 Query: 399 AQLDHCVFIQRKISRPSQRPKTPLTDTSVYTELPNAEPRSKVVSCPRAPQSG 450 A + H Q P Y E+ ++ PR ++ S P +P SG Sbjct: 535 AAVKHTQPEDGVEMDTRQSPHDEDPQAVTYAEVKHSRPRREMAS-PPSPLSG 585 Score = 195 bits (495), Expect = 8e-50 Identities = 132/347 (38%), Positives = 184/347 (53%), Gaps = 20/347 (5%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 M+ + + C+G L G KP L A P +V+ +G V L+C + + L Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60 Query: 61 YKEDRSHVPIFHGRIFQE-----SFIMGPVTPAHAGTYRCR-GSRPHSLTGWSAPSNPLV 114 Y+E ++ + I RI QE F + +T HAG YRC GS G S S+PL Sbjct: 61 YREKKTALWIT--RIPQELVKKGQFPIPSITWEHAGRYRCYYGS---DTAGRSESSDPLE 115 Query: 115 IMVTGNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIH-D 173 ++VTG + KP+L A P P++ SG VILQC S V F+ F L +EG E P L Q H Sbjct: 116 LVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHAR 175 Query: 174 GVSKANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPT 233 G S+A FS+GP+ P YRCY +SPY+ S PSD L++++ G+ +KPSLS QPGP Sbjct: 176 GSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPI 235 Query: 234 VQAGENVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPA--THGGTY 291 V E +TL C S + Y+ + L ++GE +L QA+F LGP ++GG Y Sbjct: 236 VAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQY 295 Query: 292 RCFGSFRALPCVWSNSSDPLLVSVTGN-----PSSSWPSPTEPSSKS 333 RC+G+ L WS SDPL + + G S P PT S ++ Sbjct: 296 RCYGAHN-LSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGEN 341 Score = 32.3 bits (72), Expect = 0.91 Identities = 20/60 (33%), Positives = 35/60 (58%), Gaps = 4/60 (6%) Query: 374 DQEPAGDRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISR--PSQRPKTPLTDTSVYTEL 431 D++ DR ++ + + + PQ+VTYAQL H + ++R+ + PSQ +P S+Y L Sbjct: 592 DRQAEEDRQMDTEAAASEAPQDVTYAQL-HSLTLRREATEPPPSQEGPSPAV-PSIYATL 649 >gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B, member 1 isoform 1 [Homo sapiens] Length = 650 Score = 252 bits (644), Expect = 4e-67 Identities = 181/471 (38%), Positives = 254/471 (53%), Gaps = 51/471 (10%) Query: 24 GGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFMLYKEDRSHVPIF-----HGRIFQE 78 G KP LSA+PS VV GG+V LQC + F+ F L KE P H R Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179 Query: 79 S-FIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGNHRKPSLLAHPGPLLKSG 137 + F +GPV+P+ YRC +S WS PS+ L ++V G +KPSL PGP++ Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239 Query: 138 ETVILQCWSDVMFEHFFLHREGISEDPSRLVG-QIHDGVSKANFSIGPLMPVLAGTYRCY 196 ET+ LQC SD + F L+++G D +L G Q G+S+ANF++GP+ G YRCY Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDG-ERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCY 298 Query: 197 GSVPHSPYQLSAPSDPLDIVITG-LYEKPSLSAQPGPTVQAGENVTLSCSSWSSYDIYHL 255 G+ S + SAPSDPLDI+I G Y++ SLS QPGPTV +GENVTL C S + L Sbjct: 299 GAHNLSS-EWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLL 357 Query: 256 SREGEAHER-RLRAVPKVNRTFQADFPLGPAT--HGGTYRCFGSFRALPCVWSNSSDPLL 312 ++EG A + RLR+ + ++ +QA+FP+GP T H GTYRC+GS + P + ++ SDPL Sbjct: 358 TKEGAADDPWRLRSTYQ-SQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLE 416 Query: 313 VSV---TGNPSSSWPSPTEPSS-------------KSGICRHLHVLIG--TSVVIFLFIL 354 + V +G PSS PT S +SG+ RHL V+IG +V++ L +L Sbjct: 417 LVVSGPSGGPSSPTTGPTSTSGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVILLLLLL 476 Query: 355 LLFFLLYR-------WCSNKKNAAVMDQEPAG-------DRTVNRQDSDEQDPQEVT-YA 399 LL FL+ R W S ++ A Q PAG DR + + S D QE YA Sbjct: 477 LLLFLILRHRRQGKHWTSTQRKADF--QHPAGAVGPEPTDRGLQWRSSPAADAQEENLYA 534 Query: 400 QLDHCVFIQRKISRPSQRPKTPLTDTSVYTELPNAEPRSKVVSCPRAPQSG 450 + H + + ++ P Y E+ ++ PR ++ S P +P SG Sbjct: 535 AVKH-TQPEDGVEMDTRSPHDEDPQAVTYAEVKHSRPRREMAS-PPSPLSG 583 Score = 195 bits (495), Expect = 8e-50 Identities = 132/347 (38%), Positives = 184/347 (53%), Gaps = 20/347 (5%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 M+ + + C+G L G KP L A P +V+ +G V L+C + + L Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60 Query: 61 YKEDRSHVPIFHGRIFQE-----SFIMGPVTPAHAGTYRCR-GSRPHSLTGWSAPSNPLV 114 Y+E ++ + I RI QE F + +T HAG YRC GS G S S+PL Sbjct: 61 YREKKTALWIT--RIPQELVKKGQFPIPSITWEHAGRYRCYYGS---DTAGRSESSDPLE 115 Query: 115 IMVTGNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIH-D 173 ++VTG + KP+L A P P++ SG VILQC S V F+ F L +EG E P L Q H Sbjct: 116 LVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHAR 175 Query: 174 GVSKANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPT 233 G S+A FS+GP+ P YRCY +SPY+ S PSD L++++ G+ +KPSLS QPGP Sbjct: 176 GSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPI 235 Query: 234 VQAGENVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPA--THGGTY 291 V E +TL C S + Y+ + L ++GE +L QA+F LGP ++GG Y Sbjct: 236 VAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQY 295 Query: 292 RCFGSFRALPCVWSNSSDPLLVSVTGN-----PSSSWPSPTEPSSKS 333 RC+G+ L WS SDPL + + G S P PT S ++ Sbjct: 296 RCYGAHN-LSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGEN 341 Score = 32.3 bits (72), Expect = 0.91 Identities = 20/60 (33%), Positives = 35/60 (58%), Gaps = 4/60 (6%) Query: 374 DQEPAGDRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISR--PSQRPKTPLTDTSVYTEL 431 D++ DR ++ + + + PQ+VTYAQL H + ++R+ + PSQ +P S+Y L Sbjct: 590 DRQAEEDRQMDTEAAASEAPQDVTYAQL-HSLTLRREATEPPPSQEGPSPAV-PSIYATL 647 >gi|110611910 leukocyte immunoglobulin-like receptor, subfamily A, member 6 [Homo sapiens] Length = 481 Score = 243 bits (619), Expect = 3e-64 Identities = 148/366 (40%), Positives = 220/366 (60%), Gaps = 19/366 (5%) Query: 22 LMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFMLYKEDRSHVPI------FHGRI 75 + G +KP LSA PS VV GG++ L+C ++G+++F+L KE +P H Sbjct: 117 MTGFYNKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGG 176 Query: 76 FQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGNHRKPSLLAHPGPLLK 135 FQ F +GPVTP+H + C ++ WS PS+PL I+ +G RKPSLL GP+L Sbjct: 177 FQALFPVGPVTPSHRWRFTCYYYYTNTPRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLA 236 Query: 136 SGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANFSIGPLMPVLAGTYRC 195 G+++ LQC SDV ++ F L++EG + R Q G+S+ANF++GP+ P G YRC Sbjct: 237 PGQSLTLQCGSDVGYDRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSHGGQYRC 296 Query: 196 YGSVPHSPYQLSAPSDPLDIVITG-LYEKPSLSAQPGPTVQAGENVTLSCSSWSSYDIYH 254 YG+ S + SAPSDPL+I++ G +Y+ SLSAQPGPTV +GENVTL C S +D + Sbjct: 297 YGAHNLSS-EWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSRGYFDTFL 355 Query: 255 LSREGEAH-ERRLRAVPKVNRTFQADFPLGPAT--HGGTYRCFGSFRALPCVWSNSSDPL 311 L++EG AH RLR++ ++ +QA+FP+ P T H GTYRC+GS+ + P + S S+PL Sbjct: 356 LTKEGAAHPPLRLRSMYGAHK-YQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSFPSEPL 414 Query: 312 LVSVTGNPSSSWPSPTEPSS------KSGICRHLHVLIGTSVVIFLFILLLFFLLYRWCS 365 + V+G+ S PT P S K +L + +G + ++ +F+ +L F Sbjct: 415 ELMVSGHSGGSSLPPTGPPSTPASHAKDYTVENL-IRMGMAGLVLVFLGILLFEAQHSQR 473 Query: 366 NKKNAA 371 N ++AA Sbjct: 474 NPQDAA 479 Score = 173 bits (438), Expect = 3e-43 Identities = 117/345 (33%), Positives = 171/345 (49%), Gaps = 17/345 (4%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 M+ + ++ C+G L G KP L A P +V+ G V + C + L Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSLEAQEYQL 60 Query: 61 YKEDRSHVPIFHGRIFQES----FIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIM 116 KE S P+ + F + +T HAG YRC +S GWS PS+PL ++ Sbjct: 61 DKEG-SPEPLDRNNPLEPKNKARFSIPSMTQHHAGRYRCHY---YSSAGWSEPSDPLELV 116 Query: 117 VTGNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVG-QIHDGV 175 +TG + KP+L A P P++ SG + L+C S + HF L +EG + P L Q+H G Sbjct: 117 MTGFYNKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGG 176 Query: 176 SKANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQ 235 +A F +GP+ P + CY ++P S PSDPL+I+ +G+ KPSL GP + Sbjct: 177 FQALFPVGPVTPSHRWRFTCYYYYTNTPRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLA 236 Query: 236 AGENVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPA--THGGTYRC 293 G+++TL C S YD + L +EGE + QA+F LGP +HGG YRC Sbjct: 237 PGQSLTLQCGSDVGYDRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSHGGQYRC 296 Query: 294 FGSFRALPCVWSNSSDPLLVSVTGN-----PSSSWPSPTEPSSKS 333 +G+ L WS SDPL + + G S+ P PT S ++ Sbjct: 297 YGAHN-LSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGEN 340 >gi|125987591 leukocyte immunoglobulin-like receptor, subfamily B, member 5 isoform 1 [Homo sapiens] Length = 591 Score = 234 bits (597), Expect = 1e-61 Identities = 162/467 (34%), Positives = 228/467 (48%), Gaps = 64/467 (13%) Query: 28 KPFLSARPSTVVPRGGHVALQCHYRRGFNNFMLYKEDRSHVPIFHGRIF-----QESFIM 82 +P L A PS VV GG+V LQC G F+L +E++ + + Q F + Sbjct: 123 EPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPV 182 Query: 83 GPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGNHRKPSLLAHPGPLLKSGETVIL 142 GPVTP+ +RC + WS PS+ L I+V G RKPSLL G ++ G ++ L Sbjct: 183 GPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTL 242 Query: 143 QCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANFSIGPLMPVLAGTYRCYGSVPHS 202 QC SDV ++ F L++EG + Q G+S+ANF++GP+ G YRCYG+ S Sbjct: 243 QCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLS 302 Query: 203 PYQLSAPSDPLDIVITGLY-EKPSLSAQPGPTVQAGENVTLSCSSWSSYDIYHLSREGEA 261 P + SAPSDPLDI+I GL + P+LS QPGP V +GENVTL C SW D + L++EG A Sbjct: 303 P-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAA 361 Query: 262 HERRLRAVPKVNRTFQADFPLGPAT--HGGTYRCFGSFRALPCVWSNSSDPLLVSVTG-- 317 H + QA+F + P T GGTYRC+ + R+ P + S+ S P + V+G Sbjct: 362 HPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPS 421 Query: 318 -----NPSSSWPSPTEPSS----------KSGICRHLHVLIGTSVVIFLFILLLFFLLYR 362 +P+ S P+P P +SG+ RHL V+ G SV L + LL FLL R Sbjct: 422 GDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLGRHLGVVTGVSVAFVLLLFLLLFLLLR 481 Query: 363 WCSNKK--------------------------------------NAAVMDQEPAGDRTVN 384 K NAAV D +P ++ Sbjct: 482 HRHQSKHRTSAHFYRPAGAAGPEPKDQGLQKRASPVADIQEEILNAAVKDTQPKDGVEMD 541 Query: 385 RQDSDEQDPQEVTYAQLDHCVFIQRKISRPSQRPKTPLTDTSVYTEL 431 + + + PQ+VTYAQL + P + + P + S+Y L Sbjct: 542 ARAAASEAPQDVTYAQLHSLTLRREATEPPPSQEREPPAEPSIYAPL 588 Score = 152 bits (384), Expect = 6e-37 Identities = 112/326 (34%), Positives = 158/326 (48%), Gaps = 17/326 (5%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 M+LT+ + C+G + G KP L A P++V+ RG V L C + L Sbjct: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60 Query: 61 YKED-----RSHVPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVI 115 KE + P+ G + F + AG YRC P GWS PS+PL + Sbjct: 61 DKEGLPWARKRQNPLEPGA--KAKFHIPSTVYDSAGRYRCYYETP---AGWSEPSDPLEL 115 Query: 116 MVTGNHRKPSLLAHPGPLLKSGETVILQCWS-DVMFEHFFLHREGISEDPSRLVGQ-IHD 173 + TG + +P+LLA P P++ SG V LQC + D + + E + P L Q + Sbjct: 116 VATGFYAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEE--QKLPRTLYSQKLPK 173 Query: 174 GVSKANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPT 233 G S+A F +GP+ P +RCY +P S PSD L+I++ G+ KPSL G Sbjct: 174 GPSQALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSV 233 Query: 234 VQAGENVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPA--THGGTY 291 V G ++TL C S YDI+ L +EGE + QA+F LGP +HGG Y Sbjct: 234 VARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQY 293 Query: 292 RCFGSFRALPCVWSNSSDPLLVSVTG 317 RC+G+ P WS SDPL + + G Sbjct: 294 RCYGAHNLSP-RWSAPSDPLDILIAG 318 Score = 138 bits (347), Expect = 1e-32 Identities = 85/221 (38%), Positives = 119/221 (53%), Gaps = 9/221 (4%) Query: 24 GGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFMLYKEDRSHVPIFHGR-----IFQE 78 G KP L +VV RGG + LQC G++ F+LYKE + G+ + Q Sbjct: 219 GVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQA 278 Query: 79 SFIMGPVTPAHAGTYRCRGSRPHSLTG-WSAPSNPLVIMVTGNHRK-PSLLAHPGPLLKS 136 +F +GPV+ +H G YRC G+ H+L+ WSAPS+PL I++ G P+L PGP + S Sbjct: 279 NFTLGPVSRSHGGQYRCYGA--HNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVAS 336 Query: 137 GETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANFSIGPLMPVLAGTYRCY 196 GE V L C S + FFL +EG + P L + +A FS+ P+ GTYRCY Sbjct: 337 GENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCY 396 Query: 197 GSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAG 237 ++ PY LS+PS P ++V++G PSLS AG Sbjct: 397 SAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAG 437 >gi|5803070 leukocyte immunoglobulin-like receptor, subfamily B, member 5 isoform 2 [Homo sapiens] Length = 590 Score = 232 bits (592), Expect = 5e-61 Identities = 162/466 (34%), Positives = 228/466 (48%), Gaps = 63/466 (13%) Query: 28 KPFLSARPSTVVPRGGHVALQCHYRRGFNNFMLYKEDRSHVPIFHGRIF-----QESFIM 82 +P L A PS VV GG+V LQC G F+L +E++ + + Q F + Sbjct: 123 EPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPV 182 Query: 83 GPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGNHRKPSLLAHPGPLLKSGETVIL 142 GPVTP+ +RC + WS PS+ L I+V G RKPSLL G ++ G ++ L Sbjct: 183 GPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTL 242 Query: 143 QCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANFSIGPLMPVLAGTYRCYGSVPHS 202 QC SDV ++ F L++EG + Q G+S+ANF++GP+ G YRCYG+ S Sbjct: 243 QCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLS 302 Query: 203 PYQLSAPSDPLDIVITGLY-EKPSLSAQPGPTVQAGENVTLSCSSWSSYDIYHLSREGEA 261 P + SAPSDPLDI+I GL + P+LS QPGP V +GENVTL C SW D + L++EG A Sbjct: 303 P-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAA 361 Query: 262 HERRLRAVPKVNRTFQADFPLGPAT--HGGTYRCFGSFRALPCVWSNSSDPLLVSVTG-- 317 H + QA+F + P T GGTYRC+ + R+ P + S+ S P + V+G Sbjct: 362 HPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPS 421 Query: 318 -----NPSSSWP---------SPTEPSSKSGICRHLHVLIGTSVVIFLFILLLFFLLYRW 363 +P+ S P +PT +SG+ RHL V+ G SV L + LL FLL R Sbjct: 422 GDPSLSPTGSTPTPGPEDQPLTPTGLDPQSGLGRHLGVVTGVSVAFVLLLFLLLFLLLRH 481 Query: 364 CSNKK--------------------------------------NAAVMDQEPAGDRTVNR 385 K NAAV D +P ++ Sbjct: 482 RHQSKHRTSAHFYRPAGAAGPEPKDQGLQKRASPVADIQEEILNAAVKDTQPKDGVEMDA 541 Query: 386 QDSDEQDPQEVTYAQLDHCVFIQRKISRPSQRPKTPLTDTSVYTEL 431 + + + PQ+VTYAQL + P + + P + S+Y L Sbjct: 542 RAAASEAPQDVTYAQLHSLTLRREATEPPPSQEREPPAEPSIYAPL 587 Score = 152 bits (384), Expect = 6e-37 Identities = 112/326 (34%), Positives = 158/326 (48%), Gaps = 17/326 (5%) Query: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60 M+LT+ + C+G + G KP L A P++V+ RG V L C + L Sbjct: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60 Query: 61 YKED-----RSHVPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVI 115 KE + P+ G + F + AG YRC P GWS PS+PL + Sbjct: 61 DKEGLPWARKRQNPLEPGA--KAKFHIPSTVYDSAGRYRCYYETP---AGWSEPSDPLEL 115 Query: 116 MVTGNHRKPSLLAHPGPLLKSGETVILQCWS-DVMFEHFFLHREGISEDPSRLVGQ-IHD 173 + TG + +P+LLA P P++ SG V LQC + D + + E + P L Q + Sbjct: 116 VATGFYAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEE--QKLPRTLYSQKLPK 173 Query: 174 GVSKANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPT 233 G S+A F +GP+ P +RCY +P S PSD L+I++ G+ KPSL G Sbjct: 174 GPSQALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSV 233 Query: 234 VQAGENVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPA--THGGTY 291 V G ++TL C S YDI+ L +EGE + QA+F LGP +HGG Y Sbjct: 234 VARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQY 293 Query: 292 RCFGSFRALPCVWSNSSDPLLVSVTG 317 RC+G+ P WS SDPL + + G Sbjct: 294 RCYGAHNLSP-RWSAPSDPLDILIAG 318 Score = 138 bits (347), Expect = 1e-32 Identities = 87/224 (38%), Positives = 121/224 (54%), Gaps = 14/224 (6%) Query: 24 GGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFMLYKEDRSHVPIFHGR-----IFQE 78 G KP L +VV RGG + LQC G++ F+LYKE + G+ + Q Sbjct: 219 GVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQA 278 Query: 79 SFIMGPVTPAHAGTYRCRGSRPHSLTG-WSAPSNPLVIMVTGNHRK-PSLLAHPGPLLKS 136 +F +GPV+ +H G YRC G+ H+L+ WSAPS+PL I++ G P+L PGP + S Sbjct: 279 NFTLGPVSRSHGGQYRCYGA--HNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVAS 336 Query: 137 GETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANFSIGPLMPVLAGTYRCY 196 GE V L C S + FFL +EG + P L + +A FS+ P+ GTYRCY Sbjct: 337 GENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCY 396 Query: 197 GSVPHSPYQLSAPSDPLDIVITGLYEKPSLS-----AQPGPTVQ 235 ++ PY LS+PS P ++V++G PSLS PGP Q Sbjct: 397 SAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPGPEDQ 440 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.136 0.433 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,799,451 Number of Sequences: 37866 Number of extensions: 1089956 Number of successful extensions: 3884 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 76 Number of HSP's successfully gapped in prelim test: 35 Number of HSP's that attempted gapping in prelim test: 2924 Number of HSP's gapped (non-prelim): 288 length of query: 455 length of database: 18,247,518 effective HSP length: 106 effective length of query: 349 effective length of database: 14,233,722 effective search space: 4967568978 effective search space used: 4967568978 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.