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Search of human proteins with 134133244
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|134133244 killer cell immunoglobulin-like receptor, three
domains, short cytoplasmic tail, 1 [Homo sapiens]
(382 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|134133244 killer cell immunoglobulin-like receptor, three dom... 810 0.0
gi|134268644 killer cell immunoglobulin-like receptor, three dom... 742 0.0
gi|134268642 killer cell immunoglobulin-like receptor, three dom... 640 0.0
gi|46488946 killer cell immunoglobulin-like receptor, three doma... 527 e-150
gi|62632748 killer-cell Ig-like receptor [Homo sapiens] 485 e-137
gi|6912472 killer cell immunoglobulin-like receptor, two domains... 446 e-125
gi|7657277 killer cell immunoglobulin-like receptor, two domains... 438 e-123
gi|116517309 killer cell immunoglobulin-like receptor, two domai... 434 e-122
gi|134304835 killer cell immunoglobulin-like receptor, two domai... 432 e-121
gi|71143139 killer cell immunoglobulin-like receptor, two domain... 430 e-121
gi|134304833 killer cell immunoglobulin-like receptor, two domai... 426 e-119
gi|110611923 killer cell immunoglobulin-like receptor, two domai... 422 e-118
gi|6912474 killer cell immunoglobulin-like receptor, two domains... 417 e-117
gi|124107604 killer cell immunoglobulin-like receptor, two domai... 297 1e-80
gi|124107606 killer cell immunoglobulin-like receptor, two domai... 297 1e-80
gi|11968154 killer cell immunoglobulin-like receptor, two domain... 296 2e-80
gi|66267727 killer cell immunoglobulin-like receptor, two domain... 290 1e-78
gi|124107610 killer cell immunoglobulin-like receptor, two domai... 252 3e-67
gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B... 250 1e-66
gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B... 250 1e-66
gi|110611910 leukocyte immunoglobulin-like receptor, subfamily A... 231 1e-60
gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B... 228 7e-60
gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B... 228 9e-60
gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B... 220 2e-57
gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B... 220 2e-57
gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B... 220 2e-57
gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B... 220 2e-57
gi|31543056 leukocyte immunoglobulin-like receptor, subfamily A ... 218 9e-57
gi|47519953 leukocyte immunoglobulin-like receptor subfamily A m... 216 3e-56
gi|125987593 leukocyte immunoglobulin-like receptor, subfamily B... 211 1e-54
>gi|134133244 killer cell immunoglobulin-like receptor, three
domains, short cytoplasmic tail, 1 [Homo sapiens]
Length = 382
Score = 810 bits (2093), Expect = 0.0
Identities = 382/382 (100%), Positives = 382/382 (100%)
Query: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML
Sbjct: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
Query: 61 YKEDRIHVPIFHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGN 120
YKEDRIHVPIFHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGN
Sbjct: 61 YKEDRIHVPIFHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGN 120
Query: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANF 180
HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANF
Sbjct: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANF 180
Query: 181 SIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESV 240
SIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESV
Sbjct: 181 SIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESV 240
Query: 241 TLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHS 300
TLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHS
Sbjct: 241 TLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHS 300
Query: 301 PYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFFLL 360
PYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFFLL
Sbjct: 301 PYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFFLL 360
Query: 361 HRWCSNKKKCCCNGPRACREQK 382
HRWCSNKKKCCCNGPRACREQK
Sbjct: 361 HRWCSNKKKCCCNGPRACREQK 382
>gi|134268644 killer cell immunoglobulin-like receptor, three
domains, long cytoplasmic tail, 1 precursor [Homo
sapiens]
Length = 444
Score = 742 bits (1915), Expect = 0.0
Identities = 354/368 (96%), Positives = 357/368 (97%)
Query: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
M LMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML
Sbjct: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
Query: 61 YKEDRIHVPIFHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGN 120
YKEDRIH+PIFHGRIFQE FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNP+VIMVTGN
Sbjct: 61 YKEDRIHIPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGN 120
Query: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANF 180
HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKE ISKDPSRLVGQIHDGVSKANF
Sbjct: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANF 180
Query: 181 SIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESV 240
SIG MM ALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTG YEKPSLSAQPGPKVQAGESV
Sbjct: 181 SIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESV 240
Query: 241 TLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHS 300
TLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHS
Sbjct: 241 TLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHS 300
Query: 301 PYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFFLL 360
PYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGN RHLHILIGTSVV I F +LLFFLL
Sbjct: 301 PYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNPRHLHILIGTSVVIILFILLLFFLL 360
Query: 361 HRWCSNKK 368
H WCSNKK
Sbjct: 361 HLWCSNKK 368
>gi|134268642 killer cell immunoglobulin-like receptor, three
domains, long cytoplasmic tail, 2 precursor [Homo
sapiens]
Length = 455
Score = 640 bits (1652), Expect = 0.0
Identities = 310/368 (84%), Positives = 326/368 (88%)
Query: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
M L VVSMACVG FL+Q A P MGGQDKPFLSA PS VVPRGGHV L+CHYR FNNFML
Sbjct: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60
Query: 61 YKEDRIHVPIFHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGN 120
YKEDR HVPIFHGRIFQE F M PVT AHAG Y CRGS PHS TGWSAPSNP+VIMVTGN
Sbjct: 61 YKEDRSHVPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGN 120
Query: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANF 180
HRKPSLLAHPGPL+KSGE VILQCWSD+MFEHFFLH+E IS+DPSRLVGQIHDGVSKANF
Sbjct: 121 HRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANF 180
Query: 181 SIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESV 240
SIG +M LAGTYRCYGSV H+PYQLSAPSDPLDIV+TGLYEKPSLSAQPGP VQAGE+V
Sbjct: 181 SIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGENV 240
Query: 241 TLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHS 300
TLSCSS SSYD+YHLSREG AHERRL AV KVNRTFQADFPLGPATHGGTYRCFGSFR
Sbjct: 241 TLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPATHGGTYRCFGSFRAL 300
Query: 301 PYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFFLL 360
P WS+ SDPLLVSVTGNPSSSWPSPTEPSSKSG RHLH+LIGTSVV F +LLFFLL
Sbjct: 301 PCVWSNSSDPLLVSVTGNPSSSWPSPTEPSSKSGICRHLHVLIGTSVVIFLFILLLFFLL 360
Query: 361 HRWCSNKK 368
+RWCSNKK
Sbjct: 361 YRWCSNKK 368
>gi|46488946 killer cell immunoglobulin-like receptor, three
domains, long cytoplasmic tail, 3 [Homo sapiens]
Length = 410
Score = 527 bits (1358), Expect = e-150
Identities = 260/368 (70%), Positives = 286/368 (77%), Gaps = 17/368 (4%)
Query: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
M LMVVSMACVG FL++ PH+GGQDKPFLSAWP VV G HVTL+C R FN F L
Sbjct: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60
Query: 61 YKEDRIHVPIFHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGN 120
KED + VP + RIF+ F M PVT AHAG Y C SHPHSPTGWSAPSNP+VIMVTG
Sbjct: 61 SKEDGMPVPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGV 120
Query: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANF 180
HRKPSLLAHPGPLVKSGE VILQCWSD+ FE F LH+E I++DP RLVGQ+HD S+ N+
Sbjct: 121 HRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNY 180
Query: 181 SIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESV 240
S+G M ALAGTYRC+GSVTH PY+LSAPSDPLDIVV GLY KPSLSAQPGP VQAGE+V
Sbjct: 181 SMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGENV 240
Query: 241 TLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHS 300
TLSCSSRS +D+YHLSRE A E RL AV +VN TFQA+FPLGP THGG YRCFGSFR
Sbjct: 241 TLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFRAL 300
Query: 301 PYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFFLL 360
P+ WSDPSDPL VSVTGN RHLH+LIGTSVV IPF ILLFFLL
Sbjct: 301 PHAWSDPSDPLPVSVTGNS-----------------RHLHVLIGTSVVIIPFAILLFFLL 343
Query: 361 HRWCSNKK 368
HRWC+NKK
Sbjct: 344 HRWCANKK 351
>gi|62632748 killer-cell Ig-like receptor [Homo sapiens]
Length = 328
Score = 485 bits (1249), Expect = e-137
Identities = 238/316 (75%), Positives = 257/316 (81%)
Query: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
M LMV+SMACVG FL+Q A H GGQDKPFLSAWPS VV G HV L+C R FN F L
Sbjct: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPFLSAWPSPVVSEGEHVALQCRSRLGFNEFSL 60
Query: 61 YKEDRIHVPIFHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGN 120
KED + VP + R+F+ + PVT AHAG Y CRGSHPH TGWSAPSNP+VIMVTG
Sbjct: 61 SKEDGMPVPELYNRVFRNTVFIGPVTPAHAGTYRCRGSHPHFLTGWSAPSNPLVIMVTGV 120
Query: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANF 180
HRKPSLLAHPGPLVKS E VILQCWSD+MFEHF LH+E D RL G++HDGVSKANF
Sbjct: 121 HRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLLHREGKFNDTLRLTGELHDGVSKANF 180
Query: 181 SIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESV 240
SIG M + LAGTYRCYGSV H+PYQLSAPSDPLDIV+TGL KPSLSAQP P V+AGESV
Sbjct: 181 SIGRMTQDLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLCGKPSLSAQPRPMVKAGESV 240
Query: 241 TLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHS 300
TLSCSSRSSYD+YHLSREG AHE R PAV KVN TFQA+FPLGPATHGGTYRCFGSFR S
Sbjct: 241 TLSCSSRSSYDIYHLSREGEAHELRFPAVPKVNGTFQANFPLGPATHGGTYRCFGSFRDS 300
Query: 301 PYEWSDPSDPLLVSVT 316
PYEWSD SDPLLVSVT
Sbjct: 301 PYEWSDLSDPLLVSVT 316
Score = 142 bits (358), Expect = 5e-34
Identities = 92/224 (41%), Positives = 124/224 (55%), Gaps = 11/224 (4%)
Query: 119 GNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKA 178
G KP L A P P+V GE V LQC S + F F L SK+ V ++++ V +
Sbjct: 24 GGQDKPFLSAWPSPVVSEGEHVALQCRSRLGFNEFSL-----SKEDGMPVPELYNRVFRN 78
Query: 179 NFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGE 238
IG + A AGTYRC GS H SAPS+PL I+VTG++ KPSL A PGP V++ E
Sbjct: 79 TVFIGPVTPAHAGTYRCRGSHPHFLTGWSAPSNPLVIMVTGVHRKPSLLAHPGPLVKSEE 138
Query: 239 SVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATH--GGTYRCFGS 296
+V L C S ++ + L REG ++ + +A+F +G T GTYRC+GS
Sbjct: 139 TVILQCWSDVMFEHFLLHREGKFNDTLRLTGELHDGVSKANFSIGRMTQDLAGTYRCYGS 198
Query: 297 FRHSPYEWSDPSDPLLVSVT---GNPS-SSWPSPTEPSSKSGNL 336
HSPY+ S PSDPL + +T G PS S+ P P + +S L
Sbjct: 199 VPHSPYQLSAPSDPLDIVITGLCGKPSLSAQPRPMVKAGESVTL 242
Score = 60.1 bits (144), Expect = 3e-09
Identities = 38/102 (37%), Positives = 52/102 (50%), Gaps = 9/102 (8%)
Query: 28 KPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIH------VPIFHGRIFQEGFN 81
KP LSA P +V G VTL C R ++ + L +E H VP +G FQ F
Sbjct: 223 KPSLSAQPRPMVKAGESVTLSCSSRSSYDIYHLSREGEAHELRFPAVPKVNGT-FQANFP 281
Query: 82 MSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRK 123
+ P T H G Y C GS SP WS S+P+++ VT + ++
Sbjct: 282 LGPAT--HGGTYRCFGSFRDSPYEWSDLSDPLLVSVTDSMKE 321
>gi|6912472 killer cell immunoglobulin-like receptor, two domains,
short cytoplasmic tail, 2 precursor [Homo sapiens]
Length = 304
Score = 446 bits (1147), Expect = e-125
Identities = 220/284 (77%), Positives = 235/284 (82%), Gaps = 16/284 (5%)
Query: 85 VTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSGERVILQC 144
V+ A G + +G+ PH G HRKPSLLAHPGPLVKS E VILQC
Sbjct: 6 VSMACVGFFLLQGAWPHE----------------GVHRKPSLLAHPGPLVKSEETVILQC 49
Query: 145 WSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYGSVTHTPY 204
WSD+ FEHF LH+E KD L+G+ HDGVSKANFSIG MM+ LAGTYRCYGSVTH+PY
Sbjct: 50 WSDVRFEHFLLHREGKYKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPY 109
Query: 205 QLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHER 264
QLSAPSDPLDIV+TGLYEKPSLSAQPGP V AGESVTLSCSSRSSYDMYHLSREG AHER
Sbjct: 110 QLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHER 169
Query: 265 RLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSWP 324
R A KVN TFQADFPLGPATHGGTYRCFGSFR SPYEWS+ SDPLLVSVTGNPS+SWP
Sbjct: 170 RFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWP 229
Query: 325 SPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFFLLHRWCSNKK 368
SPTEPSSK+GN RHLH+LIGTSVVKIPFTILLFFLLHRWCSNKK
Sbjct: 230 SPTEPSSKTGNPRHLHVLIGTSVVKIPFTILLFFLLHRWCSNKK 273
Score = 156 bits (394), Expect = 3e-38
Identities = 93/224 (41%), Positives = 127/224 (56%), Gaps = 7/224 (3%)
Query: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
M LMVVSMACVG FL+Q A PH G KP L A P +V V L+C RF +F+L
Sbjct: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFEHFLL 60
Query: 61 YKE----DRIH-VPIFHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVI 115
++E D +H + H + + F++ P+ AG Y C GS HSP SAPS+P+ I
Sbjct: 61 HREGKYKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
Query: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGV 175
++TG + KPSL A PGP V +GE V L C S ++ + L +E + + G +G
Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGT 180
Query: 176 SKANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTG 219
+A+F +G GTYRC+GS +PY+ S SDPL + VTG
Sbjct: 181 FQADFPLGPATH--GGTYRCFGSFRDSPYEWSNSSDPLLVSVTG 222
>gi|7657277 killer cell immunoglobulin-like receptor, two domains,
short cytoplasmic tail, 1 precursor [Homo sapiens]
Length = 304
Score = 438 bits (1126), Expect = e-123
Identities = 215/288 (74%), Positives = 237/288 (82%), Gaps = 16/288 (5%)
Query: 81 NMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSGERV 140
+++ V+ A G + +G+ PH G HRKPSLLAHPG LVKS E V
Sbjct: 2 SLTVVSMACVGFFLLQGAWPHE----------------GVHRKPSLLAHPGRLVKSEETV 45
Query: 141 ILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYGSVT 200
ILQCWSD+MFEHF LH+E + D RL+G+ HDGVSKANFSI M + LAGTYRCYGSVT
Sbjct: 46 ILQCWSDVMFEHFLLHREGMFNDTLRLIGEHHDGVSKANFSISRMKQDLAGTYRCYGSVT 105
Query: 201 HTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGG 260
H+PYQLSAPSDPLDIV+ GLYEKPSLSAQPGP V AGE+VTLSCSSRSSYDMYHLSREG
Sbjct: 106 HSPYQLSAPSDPLDIVIIGLYEKPSLSAQPGPTVLAGENVTLSCSSRSSYDMYHLSREGE 165
Query: 261 AHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPS 320
AHERRLPA KVN TFQA+FPLGPATHGGTYRCFGSFR SPYEWS SDPLLVSVTGNPS
Sbjct: 166 AHERRLPAGTKVNGTFQANFPLGPATHGGTYRCFGSFRDSPYEWSKSSDPLLVSVTGNPS 225
Query: 321 SSWPSPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFFLLHRWCSNKK 368
+SWPSPTEPSS++GN RHLH+LIGTSVVKIPFTILLFFLLHRWCS+KK
Sbjct: 226 NSWPSPTEPSSETGNPRHLHVLIGTSVVKIPFTILLFFLLHRWCSDKK 273
Score = 149 bits (375), Expect = 5e-36
Identities = 94/244 (38%), Positives = 131/244 (53%), Gaps = 11/244 (4%)
Query: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
M L VVSMACVG FL+Q A PH G KP L A P +V V L+C F +F+L
Sbjct: 1 MSLTVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
Query: 61 YKEDRIHVPI-----FHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVI 115
++E + + H + + F++S + AG Y C GS HSP SAPS+P+ I
Sbjct: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMKQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
Query: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGV 175
++ G + KPSL A PGP V +GE V L C S ++ + L +E + + G +G
Sbjct: 121 VIIGLYEKPSLSAQPGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGTKVNGT 180
Query: 176 SKANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQ 235
+ANF +G GTYRC+GS +PY+ S SDPL + VTG PS ++ P P
Sbjct: 181 FQANFPLGPATH--GGTYRCFGSFRDSPYEWSKSSDPLLVSVTG---NPS-NSWPSPTEP 234
Query: 236 AGES 239
+ E+
Sbjct: 235 SSET 238
>gi|116517309 killer cell immunoglobulin-like receptor, two domains,
short cytoplasmic tail, 4 [Homo sapiens]
Length = 304
Score = 434 bits (1116), Expect = e-122
Identities = 207/250 (82%), Positives = 223/250 (89%)
Query: 119 GNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKA 178
G HRKPS LA PG LVKS E VILQCWSD+MFEHF LH+E + L+G+ HDGVSKA
Sbjct: 24 GVHRKPSFLALPGHLVKSEETVILQCWSDVMFEHFLLHREGKFNNTLHLIGEHHDGVSKA 83
Query: 179 NFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGE 238
NFSIG MM LAGTYRCYGSV H+PYQLSAPSDPLD+V+ GLYEKPSLSAQPGP VQAGE
Sbjct: 84 NFSIGPMMPVLAGTYRCYGSVPHSPYQLSAPSDPLDMVIIGLYEKPSLSAQPGPTVQAGE 143
Query: 239 SVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFR 298
+VTLSCSSRSSYDMYHLSREG AHERRLPAVR +N TFQADFPLGPATHGGTYRCFGSFR
Sbjct: 144 NVTLSCSSRSSYDMYHLSREGEAHERRLPAVRSINGTFQADFPLGPATHGGTYRCFGSFR 203
Query: 299 HSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFF 358
+PYEWS+ SDPLLVSVTGNPS+SWPSPTEPSSK+GN RHLH+LIGTSVVKIPFTILLFF
Sbjct: 204 DAPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGNPRHLHVLIGTSVVKIPFTILLFF 263
Query: 359 LLHRWCSNKK 368
LLHRWCS+KK
Sbjct: 264 LLHRWCSDKK 273
Score = 144 bits (364), Expect = 1e-34
Identities = 84/224 (37%), Positives = 122/224 (54%), Gaps = 7/224 (3%)
Query: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
M LMV+ MACVG FL+Q A P G KP A P +V V L+C F +F+L
Sbjct: 1 MSLMVIIMACVGFFLLQGAWPQEGVHRKPSFLALPGHLVKSEETVILQCWSDVMFEHFLL 60
Query: 61 YKEDRIHVPIF-----HGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVI 115
++E + + + H + + F++ P+ AG Y C GS PHSP SAPS+P+ +
Sbjct: 61 HREGKFNNTLHLIGEHHDGVSKANFSIGPMMPVLAGTYRCYGSVPHSPYQLSAPSDPLDM 120
Query: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGV 175
++ G + KPSL A PGP V++GE V L C S ++ + L +E + + + +G
Sbjct: 121 VIIGLYEKPSLSAQPGPTVQAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAVRSINGT 180
Query: 176 SKANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTG 219
+A+F +G GTYRC+GS PY+ S SDPL + VTG
Sbjct: 181 FQADFPLGPATH--GGTYRCFGSFRDAPYEWSNSSDPLLVSVTG 222
Score = 63.5 bits (153), Expect = 3e-10
Identities = 39/104 (37%), Positives = 53/104 (50%), Gaps = 9/104 (8%)
Query: 23 MGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIH------VPIFHGRIF 76
+G +KP LSA P V G +VTL C R ++ + L +E H V +G F
Sbjct: 123 IGLYEKPSLSAQPGPTVQAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAVRSINGT-F 181
Query: 77 QEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGN 120
Q F + P T H G Y C GS +P WS S+P+++ VTGN
Sbjct: 182 QADFPLGPAT--HGGTYRCFGSFRDAPYEWSNSSDPLLVSVTGN 223
>gi|134304835 killer cell immunoglobulin-like receptor, two domains,
short cytoplasmic tail, 5 [Homo sapiens]
Length = 304
Score = 432 bits (1112), Expect = e-121
Identities = 209/250 (83%), Positives = 221/250 (88%)
Query: 119 GNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKA 178
G RKPSLLAHPGPLVKS E VILQCWSD+MFEHF LH+E RL+G+ DGVSK
Sbjct: 24 GFRRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLLHREGTFNHTLRLIGEHIDGVSKG 83
Query: 179 NFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGE 238
NFSIG M + LAGTYRCYGSVTH+PYQLSAPSDPLDIV+TGLYEKPSLSAQPGP V AGE
Sbjct: 84 NFSIGRMTQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGE 143
Query: 239 SVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFR 298
SVTLSCSSRSSYDMYHLSREG AHERRLPA KVNRTFQADFPL PATHGGTYRCFGSFR
Sbjct: 144 SVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNRTFQADFPLDPATHGGTYRCFGSFR 203
Query: 299 HSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFF 358
SPYEWS SDPLLVSVTGN S+SWPSPTEPSS++GN RHLH+LIGTSVVK+PFTILLFF
Sbjct: 204 DSPYEWSKSSDPLLVSVTGNSSNSWPSPTEPSSETGNPRHLHVLIGTSVVKLPFTILLFF 263
Query: 359 LLHRWCSNKK 368
LLHRWCSNKK
Sbjct: 264 LLHRWCSNKK 273
Score = 140 bits (352), Expect = 2e-33
Identities = 91/244 (37%), Positives = 129/244 (52%), Gaps = 11/244 (4%)
Query: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
M LMV+SMACV FL+Q A PH G + KP L A P +V V L+C F +F+L
Sbjct: 1 MSLMVISMACVAFFLLQGAWPHEGFRRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLL 60
Query: 61 YKEDRI-HVPIFHGR----IFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVI 115
++E H G + + F++ +T AG Y C GS HSP SAPS+P+ I
Sbjct: 61 HREGTFNHTLRLIGEHIDGVSKGNFSIGRMTQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
Query: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGV 175
++TG + KPSL A PGP V +GE V L C S ++ + L +E + + G +
Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNRT 180
Query: 176 SKANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQ 235
+A+F + GTYRC+GS +PY+ S SDPL + VTG S ++ P P
Sbjct: 181 FQADFPLDPATH--GGTYRCFGSFRDSPYEWSKSSDPLLVSVTG----NSSNSWPSPTEP 234
Query: 236 AGES 239
+ E+
Sbjct: 235 SSET 238
>gi|71143139 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 3 isoform 2 [Homo sapiens]
Length = 341
Score = 430 bits (1106), Expect = e-121
Identities = 207/250 (82%), Positives = 221/250 (88%)
Query: 119 GNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKA 178
G HRKPSLLAHPGPLVKS E VILQCWSD+ F+HF LH+E KD L+G+ HDGVSKA
Sbjct: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83
Query: 179 NFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGE 238
NFSIG MM+ LAGTYRCYGSVTH+PYQLSAPSDPLDIV+TGLYEKPSLSAQPGP V AGE
Sbjct: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGE 143
Query: 239 SVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFR 298
SVTLSCSSRSSYDMYHLSREG AHERR A KVN TFQADFPLGPATHGGTYRCFGSFR
Sbjct: 144 SVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFR 203
Query: 299 HSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFF 358
SPYEWS+ SDPLLVSVTGNPS+SWPSPTEPSS++GN RHLH+LIGTSVV I F +LLFF
Sbjct: 204 DSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSETGNPRHLHVLIGTSVVIILFILLLFF 263
Query: 359 LLHRWCSNKK 368
LLHRWC NKK
Sbjct: 264 LLHRWCCNKK 273
Score = 155 bits (392), Expect = 6e-38
Identities = 97/244 (39%), Positives = 135/244 (55%), Gaps = 11/244 (4%)
Query: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
M LMVVSM CVG FL+Q A PH G KP L A P +V V L+C RF +F+L
Sbjct: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60
Query: 61 YKE----DRIH-VPIFHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVI 115
++E D +H + H + + F++ P+ AG Y C GS HSP SAPS+P+ I
Sbjct: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
Query: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGV 175
++TG + KPSL A PGP V +GE V L C S ++ + L +E + + G +G
Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGT 180
Query: 176 SKANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQ 235
+A+F +G GTYRC+GS +PY+ S SDPL + VTG PS ++ P P
Sbjct: 181 FQADFPLGPATH--GGTYRCFGSFRDSPYEWSNSSDPLLVSVTG---NPS-NSWPSPTEP 234
Query: 236 AGES 239
+ E+
Sbjct: 235 SSET 238
>gi|134304833 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 2 precursor [Homo sapiens]
Length = 348
Score = 426 bits (1096), Expect = e-119
Identities = 216/284 (76%), Positives = 230/284 (80%), Gaps = 17/284 (5%)
Query: 85 VTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSGERVILQC 144
V+ A G + +G+ PH G HRKPSLLAHPG LVKS E VILQC
Sbjct: 6 VSMACVGFFLLQGAWPHE----------------GVHRKPSLLAHPGRLVKSEETVILQC 49
Query: 145 WSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYGSVTHTPY 204
WSD+ FEHF LH+E KD L+G+ HDGVSKANFSIG MM+ LAGTYRCYGSVTH+PY
Sbjct: 50 WSDVRFEHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPY 109
Query: 205 QLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHER 264
QLSAPSDPLDIV+TGLYEKPSLSAQPGP V AGESVTLSCSSRSSYDMYHLSREG AHE
Sbjct: 110 QLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHEC 169
Query: 265 RLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSWP 324
R A KVN TFQADFPLGPATHGGTYRCFGSFR SPYEWS+ SDPLLVSVTGNPS+SWP
Sbjct: 170 RFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWP 229
Query: 325 SPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFFLLHRWCSNKK 368
SPTEPSSK+GN RHLHILIGTSVV I F ILLFFLLHRWCSNKK
Sbjct: 230 SPTEPSSKTGNPRHLHILIGTSVVIILF-ILLFFLLHRWCSNKK 272
Score = 155 bits (393), Expect = 4e-38
Identities = 93/224 (41%), Positives = 127/224 (56%), Gaps = 7/224 (3%)
Query: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
M LMVVSMACVG FL+Q A PH G KP L A P +V V L+C RF +F+L
Sbjct: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
Query: 61 YKE----DRIH-VPIFHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVI 115
++E D +H + H + + F++ P+ AG Y C GS HSP SAPS+P+ I
Sbjct: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
Query: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGV 175
++TG + KPSL A PGP V +GE V L C S ++ + L +E + + G +G
Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT 180
Query: 176 SKANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTG 219
+A+F +G GTYRC+GS +PY+ S SDPL + VTG
Sbjct: 181 FQADFPLGPATH--GGTYRCFGSFRDSPYEWSNSSDPLLVSVTG 222
>gi|110611923 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 1 [Homo sapiens]
Length = 348
Score = 422 bits (1085), Expect = e-118
Identities = 213/284 (75%), Positives = 229/284 (80%), Gaps = 17/284 (5%)
Query: 85 VTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSGERVILQC 144
V+ A G + +G+ PH G HRKPSLLAHPG LVKS E VILQC
Sbjct: 6 VSMACVGFFLLQGAWPHE----------------GVHRKPSLLAHPGRLVKSEETVILQC 49
Query: 145 WSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYGSVTHTPY 204
WSD+MFEHF LH+E + D RL+G+ HDGVSKANFSI M + LAGTYRCYGSVTH+PY
Sbjct: 50 WSDVMFEHFLLHREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPY 109
Query: 205 QLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHER 264
Q+SAPSDPLDIV+ GLYEKPSLSAQ GP V AGE+VTLSCSSRSSYDMYHLSREG AHER
Sbjct: 110 QVSAPSDPLDIVIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHER 169
Query: 265 RLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSWP 324
RLPA KVN TFQADFPLGPATHGGTYRCFGSF SPYEWS SDPLLVSVTGNPS+SWP
Sbjct: 170 RLPAGPKVNGTFQADFPLGPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWP 229
Query: 325 SPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFFLLHRWCSNKK 368
SPTEPSSK+GN RHLHILIGTSVV I F ILLFFLLHRWCSNKK
Sbjct: 230 SPTEPSSKTGNPRHLHILIGTSVVIILF-ILLFFLLHRWCSNKK 272
Score = 145 bits (365), Expect = 8e-35
Identities = 88/224 (39%), Positives = 123/224 (54%), Gaps = 7/224 (3%)
Query: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
M L+VVSMACVG FL+Q A PH G KP L A P +V V L+C F +F+L
Sbjct: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
Query: 61 YKEDRIHVPI-----FHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVI 115
++E + + H + + F++S +T AG Y C GS HSP SAPS+P+ I
Sbjct: 61 HREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDI 120
Query: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGV 175
++ G + KPSL A GP V +GE V L C S ++ + L +E + + G +G
Sbjct: 121 VIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGT 180
Query: 176 SKANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTG 219
+A+F +G GTYRC+GS +PY+ S SDPL + VTG
Sbjct: 181 FQADFPLGPATH--GGTYRCFGSFHDSPYEWSKSSDPLLVSVTG 222
>gi|6912474 killer cell immunoglobulin-like receptor, two domains,
short cytoplasmic tail, 3 [Homo sapiens]
Length = 304
Score = 417 bits (1073), Expect = e-117
Identities = 208/284 (73%), Positives = 225/284 (79%), Gaps = 16/284 (5%)
Query: 85 VTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSGERVILQC 144
++ A G + +G+ PH G RKPSLLAHPG LVKS E VILQC
Sbjct: 6 ISMACVGFFWLQGAWPHE----------------GFRRKPSLLAHPGRLVKSEETVILQC 49
Query: 145 WSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYGSVTHTPY 204
WSD+MFEHF LH+E D RL+G+ DGVSKANFSIG M + LAGTYRCYGSV H+PY
Sbjct: 50 WSDVMFEHFLLHREGTFNDTLRLIGEHIDGVSKANFSIGRMRQDLAGTYRCYGSVPHSPY 109
Query: 205 QLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHER 264
Q SAPSDPLDIV+TGLYEKPSLSAQPGP V AGESVTLSCSS SSYDMYHLS EG AHER
Sbjct: 110 QFSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSWSSYDMYHLSTEGEAHER 169
Query: 265 RLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSWP 324
R A KVN TFQADFPLGPAT GGTYRCFGSF SPYEWS SDPLLVSVTGNPS+SWP
Sbjct: 170 RFSAGPKVNGTFQADFPLGPATQGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWP 229
Query: 325 SPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFFLLHRWCSNKK 368
SPTEPSSK+GN RHLH+LIGTSVVK+PFTILLFFLLHRWCS+KK
Sbjct: 230 SPTEPSSKTGNPRHLHVLIGTSVVKLPFTILLFFLLHRWCSDKK 273
Score = 145 bits (366), Expect = 6e-35
Identities = 89/224 (39%), Positives = 126/224 (56%), Gaps = 7/224 (3%)
Query: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
M LMV+SMACVG F +Q A PH G + KP L A P +V V L+C F +F+L
Sbjct: 1 MSLMVISMACVGFFWLQGAWPHEGFRRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
Query: 61 YKE----DRIHVPIFH-GRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVI 115
++E D + + H + + F++ + AG Y C GS PHSP +SAPS+P+ I
Sbjct: 61 HREGTFNDTLRLIGEHIDGVSKANFSIGRMRQDLAGTYRCYGSVPHSPYQFSAPSDPLDI 120
Query: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGV 175
++TG + KPSL A PGP V +GE V L C S ++ + L E + + G +G
Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSWSSYDMYHLSTEGEAHERRFSAGPKVNGT 180
Query: 176 SKANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTG 219
+A+F +G + GTYRC+GS +PY+ S SDPL + VTG
Sbjct: 181 FQADFPLGPATQ--GGTYRCFGSFHDSPYEWSKSSDPLLVSVTG 222
>gi|124107604 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 4 isoform b [Homo sapiens]
Length = 273
Score = 297 bits (760), Expect = 1e-80
Identities = 155/250 (62%), Positives = 180/250 (72%), Gaps = 5/250 (2%)
Query: 119 GNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKA 178
G KP A P +V G V L+C F F L+K+ V ++++ +
Sbjct: 26 GGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTLYKK-----DGVPVPELYNRIFWN 80
Query: 179 NFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGE 238
+F I + A AGTYRC G H+P + SAPS+PL I+VTGLYEKPSL+A+PGP V+AGE
Sbjct: 81 SFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGLYEKPSLTARPGPTVRAGE 140
Query: 239 SVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFR 298
+VTLSCSS+SS+D+YHLSREG AHE RLPAV +N TFQADFPLGPATHG TYRCFGSF
Sbjct: 141 NVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADFPLGPATHGETYRCFGSFH 200
Query: 299 HSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFF 358
SPYEWSDPSDPL VSVTGNPSSSWPSPTEPS K+G RHLH +I SV I FTIL FF
Sbjct: 201 GSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKTGIARHLHAVIRYSVAIILFTILPFF 260
Query: 359 LLHRWCSNKK 368
LLHRWCS KK
Sbjct: 261 LLHRWCSKKK 270
Score = 238 bits (608), Expect = 5e-63
Identities = 123/228 (53%), Positives = 150/228 (65%), Gaps = 6/228 (2%)
Query: 5 VVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKED 64
V+ +AC+G FL Q H+GGQDKPF SAWPSAVVP+GGHVTLRCHYR FN F LYK+D
Sbjct: 7 VIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTLYKKD 66
Query: 65 RIHVPIFHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKP 124
+ VP + RIF F +SPVT AHAG Y CRG HPHSPT WSAPSNP+VIMVTG + KP
Sbjct: 67 GVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGLYEKP 126
Query: 125 SLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGS 184
SL A PGP V++GE V L C S F+ + L +E + + +G +A+F +G
Sbjct: 127 SLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADFPLGP 186
Query: 185 MMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGP 232
TYRC+GS +PY+ S PSDPL + VTG PS S+ P P
Sbjct: 187 ATH--GETYRCFGSFHGSPYEWSDPSDPLPVSVTG---NPS-SSWPSP 228
>gi|124107606 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 4 isoform a [Homo sapiens]
Length = 377
Score = 297 bits (760), Expect = 1e-80
Identities = 155/250 (62%), Positives = 180/250 (72%), Gaps = 5/250 (2%)
Query: 119 GNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKA 178
G KP A P +V G V L+C F F L+K+ V ++++ +
Sbjct: 26 GGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTLYKK-----DGVPVPELYNRIFWN 80
Query: 179 NFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGE 238
+F I + A AGTYRC G H+P + SAPS+PL I+VTGLYEKPSL+A+PGP V+AGE
Sbjct: 81 SFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGLYEKPSLTARPGPTVRAGE 140
Query: 239 SVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFR 298
+VTLSCSS+SS+D+YHLSREG AHE RLPAV +N TFQADFPLGPATHG TYRCFGSF
Sbjct: 141 NVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADFPLGPATHGETYRCFGSFH 200
Query: 299 HSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFF 358
SPYEWSDPSDPL VSVTGNPSSSWPSPTEPS K+G RHLH +I SV I FTIL FF
Sbjct: 201 GSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKTGIARHLHAVIRYSVAIILFTILPFF 260
Query: 359 LLHRWCSNKK 368
LLHRWCS KK
Sbjct: 261 LLHRWCSKKK 270
Score = 238 bits (608), Expect = 5e-63
Identities = 123/228 (53%), Positives = 150/228 (65%), Gaps = 6/228 (2%)
Query: 5 VVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKED 64
V+ +AC+G FL Q H+GGQDKPF SAWPSAVVP+GGHVTLRCHYR FN F LYK+D
Sbjct: 7 VIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTLYKKD 66
Query: 65 RIHVPIFHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKP 124
+ VP + RIF F +SPVT AHAG Y CRG HPHSPT WSAPSNP+VIMVTG + KP
Sbjct: 67 GVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGLYEKP 126
Query: 125 SLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGS 184
SL A PGP V++GE V L C S F+ + L +E + + +G +A+F +G
Sbjct: 127 SLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADFPLGP 186
Query: 185 MMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGP 232
TYRC+GS +PY+ S PSDPL + VTG PS S+ P P
Sbjct: 187 ATH--GETYRCFGSFHGSPYEWSDPSDPLPVSVTG---NPS-SSWPSP 228
>gi|11968154 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 5A [Homo sapiens]
Length = 375
Score = 296 bits (759), Expect = 2e-80
Identities = 160/250 (64%), Positives = 179/250 (71%), Gaps = 5/250 (2%)
Query: 119 GNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKA 178
G KP L A P +V G V L C S + F F L+KE V ++++ +
Sbjct: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKE-----DGVPVPELYNKIFWK 78
Query: 179 NFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGE 238
+ +G + A AGTYRC GS +P + SAPS+PL IVVTGL+ KPSLSAQPGP V+ GE
Sbjct: 79 SILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLFGKPSLSAQPGPTVRTGE 138
Query: 239 SVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFR 298
+VTLSCSSRSS+DMYHLSREG AHE RLPAV VN TFQADFPLGPATHGGTY CFGS
Sbjct: 139 NVTLSCSSRSSFDMYHLSREGRAHEPRLPAVPSVNGTFQADFPLGPATHGGTYTCFGSLH 198
Query: 299 HSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFF 358
SPYEWSDPSDPLLVSVTGN SSS SPTEPSSK+G RHLHILIGTSV I F IL FF
Sbjct: 199 DSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLHILIGTSVAIILFIILFFF 258
Query: 359 LLHRWCSNKK 368
LLH CSNKK
Sbjct: 259 LLHCCCSNKK 268
Score = 233 bits (594), Expect = 2e-61
Identities = 124/234 (52%), Positives = 149/234 (63%), Gaps = 3/234 (1%)
Query: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
M LMV+SMACVG FL+Q A H GGQDKP LSAWPSAVVPRGGHVTL C R F F L
Sbjct: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60
Query: 61 YKEDRIHVPIFHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGN 120
YKED + VP + +IF + M PVT AHAG Y CRGSHP SP WSAPSNP+VI+VTG
Sbjct: 61 YKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGL 120
Query: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANF 180
KPSL A PGP V++GE V L C S F+ + L +E + +P +G +A+F
Sbjct: 121 FGKPSLSAQPGPTVRTGENVTLSCSSRSSFDMYHLSREGRAHEPRLPAVPSVNGTFQADF 180
Query: 181 SIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLS-AQPGPK 233
+G GTY C+GS+ +PY+ S PSDPL + VTG S S +P K
Sbjct: 181 PLGPATH--GGTYTCFGSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSK 232
>gi|66267727 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 5B precursor [Homo sapiens]
Length = 375
Score = 290 bits (743), Expect = 1e-78
Identities = 157/250 (62%), Positives = 177/250 (70%), Gaps = 5/250 (2%)
Query: 119 GNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKA 178
G KP L A P +V G V L C S + F F L+KE V ++++ +
Sbjct: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKE-----DGVPVPELYNKIFWK 78
Query: 179 NFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGE 238
+ +G + A AGTYRC GS +P + SAPS+PL IVVTGL+ KPSLSAQPGP V+ GE
Sbjct: 79 SILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLFGKPSLSAQPGPTVRTGE 138
Query: 239 SVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFR 298
+V LSCSSRSS+DMYHLSREG AHE RLPAV V+ TFQADFPLGPATHGGTY CF S
Sbjct: 139 NVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADFPLGPATHGGTYTCFSSLH 198
Query: 299 HSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFF 358
SPYEWSDPSDPLLVSVTGN SSS SPTEPSSK+G RHLHILIGTSV I F IL FF
Sbjct: 199 DSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLHILIGTSVAIILFIILFFF 258
Query: 359 LLHRWCSNKK 368
LLH CSNKK
Sbjct: 259 LLHCCCSNKK 268
Score = 233 bits (593), Expect = 3e-61
Identities = 124/234 (52%), Positives = 148/234 (63%), Gaps = 3/234 (1%)
Query: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
M LMV+SMACVG FL+Q A H GGQDKP LSAWPSAVVPRGGHVTL C R F F L
Sbjct: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60
Query: 61 YKEDRIHVPIFHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGN 120
YKED + VP + +IF + M PVT AHAG Y CRGSHP SP WSAPSNP+VI+VTG
Sbjct: 61 YKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGL 120
Query: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANF 180
KPSL A PGP V++GE V L C S F+ + L +E + +P DG +A+F
Sbjct: 121 FGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADF 180
Query: 181 SIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLS-AQPGPK 233
+G GTY C+ S+ +PY+ S PSDPL + VTG S S +P K
Sbjct: 181 PLGPATH--GGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSK 232
>gi|124107610 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 4 isoform c [Homo sapiens]
Length = 342
Score = 252 bits (644), Expect = 3e-67
Identities = 131/215 (60%), Positives = 155/215 (72%), Gaps = 5/215 (2%)
Query: 119 GNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKA 178
G KP A P +V G V L+C F F L+K+ V ++++ +
Sbjct: 26 GGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTLYKK-----DGVPVPELYNRIFWN 80
Query: 179 NFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGE 238
+F I + A AGTYRC G H+P + SAPS+PL I+VTGLYEKPSL+A+PGP V+AGE
Sbjct: 81 SFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGLYEKPSLTARPGPTVRAGE 140
Query: 239 SVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFR 298
+VTLSCSS+SS+D+YHLSREG AHE RLPAV +N TFQADFPLGPATHG TYRCFGSF
Sbjct: 141 NVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADFPLGPATHGETYRCFGSFH 200
Query: 299 HSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKS 333
SPYEWSDPSDPL VSVTGNPSSSWPSPTEPS K+
Sbjct: 201 GSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKT 235
Score = 238 bits (608), Expect = 5e-63
Identities = 123/228 (53%), Positives = 150/228 (65%), Gaps = 6/228 (2%)
Query: 5 VVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKED 64
V+ +AC+G FL Q H+GGQDKPF SAWPSAVVP+GGHVTLRCHYR FN F LYK+D
Sbjct: 7 VIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTLYKKD 66
Query: 65 RIHVPIFHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKP 124
+ VP + RIF F +SPVT AHAG Y CRG HPHSPT WSAPSNP+VIMVTG + KP
Sbjct: 67 GVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGLYEKP 126
Query: 125 SLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGS 184
SL A PGP V++GE V L C S F+ + L +E + + +G +A+F +G
Sbjct: 127 SLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADFPLGP 186
Query: 185 MMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGP 232
TYRC+GS +PY+ S PSDPL + VTG PS S+ P P
Sbjct: 187 ATH--GETYRCFGSFHGSPYEWSDPSDPLPVSVTG---NPS-SSWPSP 228
>gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B,
member 3 isoform 1 [Homo sapiens]
Length = 632
Score = 250 bits (639), Expect = 1e-66
Identities = 147/349 (42%), Positives = 210/349 (60%), Gaps = 12/349 (3%)
Query: 24 GGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHVPI------FHGRIFQ 77
G KP LSA PS VV GG++TLRC + +++F+L KE +P H R FQ
Sbjct: 119 GAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQ 178
Query: 78 EGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSG 137
F + PVT +H +TC + ++P WS PS+P+ I+ +G RKPSLL GP++ G
Sbjct: 179 ALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPG 238
Query: 138 ERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYG 197
+ + LQC SD+ + F L+KE R Q G+S+ANF++G + + G YRCYG
Sbjct: 239 QSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYG 298
Query: 198 SVTHTPYQLSAPSDPLDIVVTG-LYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLS 256
+ + + SAPSDPL+I++ G +Y+ SLSAQPGP V +GE+VTL C S +D + L+
Sbjct: 299 A-HNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLT 357
Query: 257 REGGAH-ERRLPAVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEWSDPSDPLLV 313
+EG AH RL ++ ++ +QA+FP+ P T H GTYRC+GS+ +P+ S PS+PL +
Sbjct: 358 KEGAAHPPLRLRSMYGAHK-YQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPLEL 416
Query: 314 SVTGNPSSSWPSPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFFLLHR 362
V+G+ S PT P S G R+L +LIG SV + LL FLL R
Sbjct: 417 VVSGHSGGSSLPPTGPPSTPGLGRYLEVLIGVSVAFVLLLFLLLFLLLR 465
Score = 181 bits (458), Expect = 1e-45
Identities = 119/344 (34%), Positives = 176/344 (51%), Gaps = 17/344 (4%)
Query: 5 VVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKED 64
+ ++ C+GL L R G KP L A P +V+ G VT+ C + L+KE
Sbjct: 5 LTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEG 64
Query: 65 RIHVPIFHGRIFQEG----FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGN 120
P+ + F++ +T HAG Y C H +S GWS PS+P+ +++TG
Sbjct: 65 SPE-PLDRNNPLEPKNKARFSIPSMTEHHAGRYRC---HYYSSAGWSEPSDPLEMVMTGA 120
Query: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVG-QIHDGVSKAN 179
+ KP+L A P P+V SG + L+C S + HF L KE + P L Q+H +A
Sbjct: 121 YSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQAL 180
Query: 180 FSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGES 239
F +G + + + CY T+TP+ S PSDPL+I+ +G+ KPSL GP + G+S
Sbjct: 181 FPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQS 240
Query: 240 VTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPA--THGGTYRCFGSF 297
+TL C S Y+ + L +EG + P + QA+F LGP ++GG YRC+G+
Sbjct: 241 LTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYGAH 300
Query: 298 RHSPYEWSDPSDPLLVSVTGN-----PSSSWPSPTEPSSKSGNL 336
S EWS PSDPL + + G S+ P PT S ++ L
Sbjct: 301 NLSS-EWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTL 343
>gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B,
member 3 isoform 2 [Homo sapiens]
Length = 631
Score = 250 bits (639), Expect = 1e-66
Identities = 147/349 (42%), Positives = 210/349 (60%), Gaps = 12/349 (3%)
Query: 24 GGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHVPI------FHGRIFQ 77
G KP LSA PS VV GG++TLRC + +++F+L KE +P H R FQ
Sbjct: 119 GAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQ 178
Query: 78 EGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSG 137
F + PVT +H +TC + ++P WS PS+P+ I+ +G RKPSLL GP++ G
Sbjct: 179 ALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPG 238
Query: 138 ERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYG 197
+ + LQC SD+ + F L+KE R Q G+S+ANF++G + + G YRCYG
Sbjct: 239 QSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYG 298
Query: 198 SVTHTPYQLSAPSDPLDIVVTG-LYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLS 256
+ + + SAPSDPL+I++ G +Y+ SLSAQPGP V +GE+VTL C S +D + L+
Sbjct: 299 A-HNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLT 357
Query: 257 REGGAH-ERRLPAVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEWSDPSDPLLV 313
+EG AH RL ++ ++ +QA+FP+ P T H GTYRC+GS+ +P+ S PS+PL +
Sbjct: 358 KEGAAHPPLRLRSMYGAHK-YQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPLEL 416
Query: 314 SVTGNPSSSWPSPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFFLLHR 362
V+G+ S PT P S G R+L +LIG SV + LL FLL R
Sbjct: 417 VVSGHSGGSSLPPTGPPSTPGLGRYLEVLIGVSVAFVLLLFLLLFLLLR 465
Score = 181 bits (458), Expect = 1e-45
Identities = 119/344 (34%), Positives = 176/344 (51%), Gaps = 17/344 (4%)
Query: 5 VVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKED 64
+ ++ C+GL L R G KP L A P +V+ G VT+ C + L+KE
Sbjct: 5 LTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEG 64
Query: 65 RIHVPIFHGRIFQEG----FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGN 120
P+ + F++ +T HAG Y C H +S GWS PS+P+ +++TG
Sbjct: 65 SPE-PLDRNNPLEPKNKARFSIPSMTEHHAGRYRC---HYYSSAGWSEPSDPLEMVMTGA 120
Query: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVG-QIHDGVSKAN 179
+ KP+L A P P+V SG + L+C S + HF L KE + P L Q+H +A
Sbjct: 121 YSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQAL 180
Query: 180 FSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGES 239
F +G + + + CY T+TP+ S PSDPL+I+ +G+ KPSL GP + G+S
Sbjct: 181 FPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQS 240
Query: 240 VTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPA--THGGTYRCFGSF 297
+TL C S Y+ + L +EG + P + QA+F LGP ++GG YRC+G+
Sbjct: 241 LTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYGAH 300
Query: 298 RHSPYEWSDPSDPLLVSVTGN-----PSSSWPSPTEPSSKSGNL 336
S EWS PSDPL + + G S+ P PT S ++ L
Sbjct: 301 NLSS-EWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTL 343
>gi|110611910 leukocyte immunoglobulin-like receptor, subfamily A,
member 6 [Homo sapiens]
Length = 481
Score = 231 bits (588), Expect = 1e-60
Identities = 133/318 (41%), Positives = 195/318 (61%), Gaps = 12/318 (3%)
Query: 24 GGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHVPI------FHGRIFQ 77
G +KP LSA PS VV GG++TLRC + +++F+L KE +P H FQ
Sbjct: 119 GFYNKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGGFQ 178
Query: 78 EGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSG 137
F + PVT +H +TC + ++P WS PS+P+ I+ +G RKPSLL GP++ G
Sbjct: 179 ALFPVGPVTPSHRWRFTCYYYYTNTPRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPG 238
Query: 138 ERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYG 197
+ + LQC SD+ ++ F L+KE R Q G+S+ANF++G + + G YRCYG
Sbjct: 239 QSLTLQCGSDVGYDRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSHGGQYRCYG 298
Query: 198 SVTHTPYQLSAPSDPLDIVVTG-LYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLS 256
+ + + SAPSDPL+I++ G +Y+ SLSAQPGP V +GE+VTL C SR +D + L+
Sbjct: 299 A-HNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSRGYFDTFLLT 357
Query: 257 REGGAH-ERRLPAVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEWSDPSDPLLV 313
+EG AH RL ++ ++ +QA+FP+ P T H GTYRC+GS+ +P+ S PS+PL +
Sbjct: 358 KEGAAHPPLRLRSMYGAHK-YQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSFPSEPLEL 416
Query: 314 SVTGNPSSSWPSPTEPSS 331
V+G+ S PT P S
Sbjct: 417 MVSGHSGGSSLPPTGPPS 434
Score = 184 bits (468), Expect = 9e-47
Identities = 122/344 (35%), Positives = 175/344 (50%), Gaps = 17/344 (4%)
Query: 5 VVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKED 64
+ ++ C+GL L R G KP L A P +V+ G VT+ C + L KE
Sbjct: 5 LTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSLEAQEYQLDKEG 64
Query: 65 RIHVPIFHGRIFQEG----FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGN 120
P+ + F++ +T HAG Y C H +S GWS PS+P+ +++TG
Sbjct: 65 SPE-PLDRNNPLEPKNKARFSIPSMTQHHAGRYRC---HYYSSAGWSEPSDPLELVMTGF 120
Query: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQ-IHDGVSKAN 179
+ KP+L A P P+V SG + L+C S + HF L KE + P L Q +H G +A
Sbjct: 121 YNKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGGFQAL 180
Query: 180 FSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGES 239
F +G + + + CY T+TP S PSDPL+I+ +G+ KPSL GP + G+S
Sbjct: 181 FPVGPVTPSHRWRFTCYYYYTNTPRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQS 240
Query: 240 VTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPA--THGGTYRCFGSF 297
+TL C S YD + L +EG + P + QA+F LGP +HGG YRC+G+
Sbjct: 241 LTLQCGSDVGYDRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSHGGQYRCYGAH 300
Query: 298 RHSPYEWSDPSDPLLVSVTGN-----PSSSWPSPTEPSSKSGNL 336
S EWS PSDPL + + G S+ P PT S ++ L
Sbjct: 301 NLSS-EWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTL 343
Score = 123 bits (309), Expect = 2e-28
Identities = 81/222 (36%), Positives = 112/222 (50%), Gaps = 7/222 (3%)
Query: 24 GGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHVPIFHGR-----IFQE 78
G KP L V+ G +TL+C ++ F+LYKE G+ + Q
Sbjct: 220 GVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYDRFVLYKEGERDFLQRPGQQPQAGLSQA 279
Query: 79 GFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGN-HRKPSLLAHPGPLVKSG 137
F + PV+ +H G Y C G+H S + WSAPS+P+ I++ G + SL A PGP V SG
Sbjct: 280 NFTLGPVSPSHGGQYRCYGAHNLS-SEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASG 338
Query: 138 ERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYG 197
E V L C S F+ F L KE + P RL +A F + + A AGTYRCYG
Sbjct: 339 ENVTLLCQSRGYFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYG 398
Query: 198 SVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGES 239
S + P+ LS PS+PL+++V+G SL P A +
Sbjct: 399 SYSSNPHLLSFPSEPLELMVSGHSGGSSLPPTGPPSTPASHA 440
>gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B,
member 2 isoform 2 [Homo sapiens]
Length = 597
Score = 228 bits (581), Expect = 7e-60
Identities = 148/382 (38%), Positives = 213/382 (55%), Gaps = 39/382 (10%)
Query: 24 GGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKE-DRIHVPIFHGRIFQEG--- 79
G KP LSA PS VV GG VTL+C + F F+L KE + H + + G
Sbjct: 119 GAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSR 178
Query: 80 --FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSG 137
F++ PV+ ++ C G +SP WS+PS+ + ++V G +KPSL PGP+V G
Sbjct: 179 AIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPG 238
Query: 138 ERVILQCWSDIMFEHFFLHKEWISKDPSRLVG-QIHDGVSKANFSIGSMMRALAGTYRCY 196
E + LQC SD+ ++ F L+KE +D +L G Q G+S+ANF++G + R+ G YRCY
Sbjct: 239 ESLTLQCVSDVGYDRFVLYKEG-ERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCY 297
Query: 197 GSVTHTPYQLSAPSDPLDIVVTG-LYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHL 255
G+ + + SAPSDPLDI++TG + P +S QPGP V +GE+VTL C S + + L
Sbjct: 298 GA-HNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLL 356
Query: 256 SREGGAHER-RLPAVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEWSDPSDPLL 312
++ G A RL ++ + + +QA+FP+ P T H GTYRC+GS PY S PS+PL
Sbjct: 357 TKAGAADAPLRLRSIHEYPK-YQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLE 415
Query: 313 VSVTGNPSSSWPSPTEPSS----------------KSGNLRHLHILIG--TSVVKIPFTI 354
+ V+G S P PT P S +SG RHL ++IG +VV + +
Sbjct: 416 LVVSGPSMGSSPPPTGPISTPGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVVLLLLLL 475
Query: 355 LLFFLLHR-------WCSNKKK 369
LL FL+ R W S ++K
Sbjct: 476 LLLFLILRHRRQGKHWTSTQRK 497
Score = 203 bits (516), Expect = 2e-52
Identities = 135/347 (38%), Positives = 188/347 (54%), Gaps = 15/347 (4%)
Query: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
M +V + C+GL L R G KP L A P +V+ +G VTL C + L
Sbjct: 1 MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRL 60
Query: 61 YKEDRIHVPIFHGR--IFQEG-FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMV 117
Y+E + I R + + G F++ +T H G Y C+ +S WS S+P+V+++
Sbjct: 61 YREKKSASWITRIRPELVKNGQFHIPSITWEHTGRYGCQY---YSRARWSELSDPLVLVM 117
Query: 118 TGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHD-GVS 176
TG + KP+L A P P+V SG RV LQC S + F F L KE + P L Q H G S
Sbjct: 118 TGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSS 177
Query: 177 KANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQA 236
+A FS+G + ++RCYG ++PY S+PSD L+++V G+ +KPSLS QPGP V
Sbjct: 178 RAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAP 237
Query: 237 GESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPA--THGGTYRCF 294
GES+TL C S YD + L +EG R+LP + QA+F LGP ++GG YRC+
Sbjct: 238 GESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCY 297
Query: 295 GSFRHSPYEWSDPSDPLLVSVTGNPS-----SSWPSPTEPSSKSGNL 336
G+ S E S PSDPL + +TG S P PT S ++ L
Sbjct: 298 GAHNLSS-ECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTL 343
>gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B,
member 2 isoform 1 [Homo sapiens]
Length = 598
Score = 228 bits (580), Expect = 9e-60
Identities = 148/383 (38%), Positives = 213/383 (55%), Gaps = 40/383 (10%)
Query: 24 GGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKE-DRIHVPIFHGRIFQEG--- 79
G KP LSA PS VV GG VTL+C + F F+L KE + H + + G
Sbjct: 119 GAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSR 178
Query: 80 --FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSG 137
F++ PV+ ++ C G +SP WS+PS+ + ++V G +KPSL PGP+V G
Sbjct: 179 AIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPG 238
Query: 138 ERVILQCWSDIMFEHFFLHKEWISKDPSRLVG-QIHDGVSKANFSIGSMMRALAGTYRCY 196
E + LQC SD+ ++ F L+KE +D +L G Q G+S+ANF++G + R+ G YRCY
Sbjct: 239 ESLTLQCVSDVGYDRFVLYKEG-ERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCY 297
Query: 197 GSVTHTPYQLSAPSDPLDIVVTG-LYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHL 255
G+ + + SAPSDPLDI++TG + P +S QPGP V +GE+VTL C S + + L
Sbjct: 298 GA-HNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLL 356
Query: 256 SREGGAHER-RLPAVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEWSDPSDPLL 312
++ G A RL ++ + + +QA+FP+ P T H GTYRC+GS PY S PS+PL
Sbjct: 357 TKAGAADAPLRLRSIHEYPK-YQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLE 415
Query: 313 VSVTGNPSSSWPSPTEPSS-----------------KSGNLRHLHILIG--TSVVKIPFT 353
+ V+G S P PT P S +SG RHL ++IG +VV +
Sbjct: 416 LVVSGPSMGSSPPPTGPISTPAGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVVLLLLL 475
Query: 354 ILLFFLLHR-------WCSNKKK 369
+LL FL+ R W S ++K
Sbjct: 476 LLLLFLILRHRRQGKHWTSTQRK 498
Score = 203 bits (516), Expect = 2e-52
Identities = 135/347 (38%), Positives = 188/347 (54%), Gaps = 15/347 (4%)
Query: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
M +V + C+GL L R G KP L A P +V+ +G VTL C + L
Sbjct: 1 MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRL 60
Query: 61 YKEDRIHVPIFHGR--IFQEG-FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMV 117
Y+E + I R + + G F++ +T H G Y C+ +S WS S+P+V+++
Sbjct: 61 YREKKSASWITRIRPELVKNGQFHIPSITWEHTGRYGCQY---YSRARWSELSDPLVLVM 117
Query: 118 TGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHD-GVS 176
TG + KP+L A P P+V SG RV LQC S + F F L KE + P L Q H G S
Sbjct: 118 TGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSS 177
Query: 177 KANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQA 236
+A FS+G + ++RCYG ++PY S+PSD L+++V G+ +KPSLS QPGP V
Sbjct: 178 RAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAP 237
Query: 237 GESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPA--THGGTYRCF 294
GES+TL C S YD + L +EG R+LP + QA+F LGP ++GG YRC+
Sbjct: 238 GESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCY 297
Query: 295 GSFRHSPYEWSDPSDPLLVSVTGNPS-----SSWPSPTEPSSKSGNL 336
G+ S E S PSDPL + +TG S P PT S ++ L
Sbjct: 298 GAHNLSS-ECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTL 343
>gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 4 [Homo sapiens]
Length = 651
Score = 220 bits (560), Expect = 2e-57
Identities = 145/381 (38%), Positives = 208/381 (54%), Gaps = 37/381 (9%)
Query: 24 GGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKE-DRIHVPIFHGRIFQEG--- 79
G KP LSA PS VV GG+V L+C + F+ F L KE + H + + G
Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179
Query: 80 --FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSG 137
F++ PV+ + Y C +SP WS PS+ + ++V G +KPSL PGP+V
Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239
Query: 138 ERVILQCWSDIMFEHFFLHKEWISKDPSRLVG-QIHDGVSKANFSIGSMMRALAGTYRCY 196
E + LQC SD + F L+K+ +D +L G Q G+S+ANF++G + R+ G YRCY
Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDG-ERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCY 298
Query: 197 GSVTHTPYQLSAPSDPLDIVVTG-LYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHL 255
G+ + + SAPSDPLDI++ G Y++ SLS QPGP V +GE+VTL C S+ + L
Sbjct: 299 GA-HNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLL 357
Query: 256 SREGGAHERRLPAVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEWSDPSDPLLV 313
++EG A + ++ +QA+FP+GP T H GTYRC+GS PY + PSDPL +
Sbjct: 358 TKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLEL 417
Query: 314 SV---TGNPSSSWPSPTEPSS-------------KSGNLRHLHILIG--TSVVKIPFTIL 355
V +G PSS PT S +SG RHL ++IG +V+ + +L
Sbjct: 418 VVSGPSGGPSSPTTGPTSTSGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVILLLLLLL 477
Query: 356 LFFLLHR-------WCSNKKK 369
L FL+ R W S ++K
Sbjct: 478 LLFLILRHRRQGKHWTSTQRK 498
Score = 198 bits (503), Expect = 8e-51
Identities = 130/349 (37%), Positives = 186/349 (53%), Gaps = 18/349 (5%)
Query: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
M ++ + C+GL L R G KP L A P +V+ +G VTLRC + L
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 61 YKEDRIHVPIFHGRIFQE-----GFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVI 115
Y+E + ++ RI QE F + +T HAG Y C + G S S+P+ +
Sbjct: 61 YREKK--TALWITRIPQELVKKGQFPIPSITWEHAGRYRCY--YGSDTAGRSESSDPLEL 116
Query: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHD-G 174
+VTG + KP+L A P P+V SG VILQC S + F+ F L KE + P L Q H G
Sbjct: 117 VVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARG 176
Query: 175 VSKANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKV 234
S+A FS+G + + YRCY +++PY+ S PSD L+++V G+ +KPSLS QPGP V
Sbjct: 177 SSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIV 236
Query: 235 QAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPA--THGGTYR 292
E++TL C S + Y+ + L ++G +L + QA+F LGP ++GG YR
Sbjct: 237 APEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYR 296
Query: 293 CFGSFRHSPYEWSDPSDPLLVSVTGN-----PSSSWPSPTEPSSKSGNL 336
C+G+ S EWS PSDPL + + G S P PT S ++ L
Sbjct: 297 CYGAHNLSS-EWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTL 344
Score = 135 bits (341), Expect = 5e-32
Identities = 85/221 (38%), Positives = 116/221 (52%), Gaps = 8/221 (3%)
Query: 23 MGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHVPIFHGR-----IFQ 77
+G KP LS P +V +TL+C +N F+LYK+ G + Q
Sbjct: 220 LGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQ 279
Query: 78 EGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGN-HRKPSLLAHPGPLVKS 136
F + PV+ ++ G Y C G+H S + WSAPS+P+ I++ G + + SL PGP V S
Sbjct: 280 ANFTLGPVSRSYGGQYRCYGAHNLS-SEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVAS 338
Query: 137 GERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCY 196
GE V L C S + F L KE + DP RL +A F +G + A AGTYRCY
Sbjct: 339 GENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCY 398
Query: 197 GSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAG 237
GS + PY L+ PSDPL++VV+G PS S GP +G
Sbjct: 399 GSQSSKPYLLTHPSDPLELVVSGPSGGPS-SPTTGPTSTSG 438
>gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 3 [Homo sapiens]
Length = 651
Score = 220 bits (560), Expect = 2e-57
Identities = 145/382 (37%), Positives = 209/382 (54%), Gaps = 38/382 (9%)
Query: 24 GGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKE-DRIHVPIFHGRIFQEG--- 79
G KP LSA PS VV GG+V L+C + F+ F L KE + H + + G
Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179
Query: 80 --FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSG 137
F++ PV+ + Y C +SP WS PS+ + ++V G +KPSL PGP+V
Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239
Query: 138 ERVILQCWSDIMFEHFFLHKEWISKDPSRLVG-QIHDGVSKANFSIGSMMRALAGTYRCY 196
E + LQC SD + F L+K+ +D +L G Q G+S+ANF++G + R+ G YRCY
Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDG-ERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCY 298
Query: 197 GSVTHTPYQLSAPSDPLDIVVTG-LYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHL 255
G+ + + SAPSDPLDI++ G Y++ SLS QPGP V +GE+VTL C S+ + L
Sbjct: 299 GA-HNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLL 357
Query: 256 SREGGAHERRLPAVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEWSDPSDPLLV 313
++EG A + ++ +QA+FP+GP T H GTYRC+GS PY + PSDPL +
Sbjct: 358 TKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLEL 417
Query: 314 SV---TGNPSSSWPSPTEPSS--------------KSGNLRHLHILIG--TSVVKIPFTI 354
V +G PSS PT S+ +SG RHL ++IG +V+ + +
Sbjct: 418 VVSGPSGGPSSPTTGPTSTSAGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVILLLLLL 477
Query: 355 LLFFLLHR-------WCSNKKK 369
LL FL+ R W S ++K
Sbjct: 478 LLLFLILRHRRQGKHWTSTQRK 499
Score = 198 bits (503), Expect = 8e-51
Identities = 130/349 (37%), Positives = 186/349 (53%), Gaps = 18/349 (5%)
Query: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
M ++ + C+GL L R G KP L A P +V+ +G VTLRC + L
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 61 YKEDRIHVPIFHGRIFQE-----GFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVI 115
Y+E + ++ RI QE F + +T HAG Y C + G S S+P+ +
Sbjct: 61 YREKK--TALWITRIPQELVKKGQFPIPSITWEHAGRYRCY--YGSDTAGRSESSDPLEL 116
Query: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHD-G 174
+VTG + KP+L A P P+V SG VILQC S + F+ F L KE + P L Q H G
Sbjct: 117 VVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARG 176
Query: 175 VSKANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKV 234
S+A FS+G + + YRCY +++PY+ S PSD L+++V G+ +KPSLS QPGP V
Sbjct: 177 SSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIV 236
Query: 235 QAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPA--THGGTYR 292
E++TL C S + Y+ + L ++G +L + QA+F LGP ++GG YR
Sbjct: 237 APEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYR 296
Query: 293 CFGSFRHSPYEWSDPSDPLLVSVTGN-----PSSSWPSPTEPSSKSGNL 336
C+G+ S EWS PSDPL + + G S P PT S ++ L
Sbjct: 297 CYGAHNLSS-EWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTL 344
Score = 134 bits (338), Expect = 1e-31
Identities = 84/216 (38%), Positives = 114/216 (52%), Gaps = 8/216 (3%)
Query: 23 MGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHVPIFHGR-----IFQ 77
+G KP LS P +V +TL+C +N F+LYK+ G + Q
Sbjct: 220 LGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQ 279
Query: 78 EGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGN-HRKPSLLAHPGPLVKS 136
F + PV+ ++ G Y C G+H S + WSAPS+P+ I++ G + + SL PGP V S
Sbjct: 280 ANFTLGPVSRSYGGQYRCYGAHNLS-SEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVAS 338
Query: 137 GERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCY 196
GE V L C S + F L KE + DP RL +A F +G + A AGTYRCY
Sbjct: 339 GENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCY 398
Query: 197 GSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGP 232
GS + PY L+ PSDPL++VV+G PS S GP
Sbjct: 399 GSQSSKPYLLTHPSDPLELVVSGPSGGPS-SPTTGP 433
>gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 2 [Homo sapiens]
Length = 652
Score = 220 bits (560), Expect = 2e-57
Identities = 145/382 (37%), Positives = 209/382 (54%), Gaps = 38/382 (9%)
Query: 24 GGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKE-DRIHVPIFHGRIFQEG--- 79
G KP LSA PS VV GG+V L+C + F+ F L KE + H + + G
Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179
Query: 80 --FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSG 137
F++ PV+ + Y C +SP WS PS+ + ++V G +KPSL PGP+V
Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239
Query: 138 ERVILQCWSDIMFEHFFLHKEWISKDPSRLVG-QIHDGVSKANFSIGSMMRALAGTYRCY 196
E + LQC SD + F L+K+ +D +L G Q G+S+ANF++G + R+ G YRCY
Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDG-ERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCY 298
Query: 197 GSVTHTPYQLSAPSDPLDIVVTG-LYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHL 255
G+ + + SAPSDPLDI++ G Y++ SLS QPGP V +GE+VTL C S+ + L
Sbjct: 299 GA-HNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLL 357
Query: 256 SREGGAHERRLPAVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEWSDPSDPLLV 313
++EG A + ++ +QA+FP+GP T H GTYRC+GS PY + PSDPL +
Sbjct: 358 TKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLEL 417
Query: 314 SV---TGNPSSSWPSPTEPSS--------------KSGNLRHLHILIG--TSVVKIPFTI 354
V +G PSS PT S+ +SG RHL ++IG +V+ + +
Sbjct: 418 VVSGPSGGPSSPTTGPTSTSAGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVILLLLLL 477
Query: 355 LLFFLLHR-------WCSNKKK 369
LL FL+ R W S ++K
Sbjct: 478 LLLFLILRHRRQGKHWTSTQRK 499
Score = 198 bits (503), Expect = 8e-51
Identities = 130/349 (37%), Positives = 186/349 (53%), Gaps = 18/349 (5%)
Query: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
M ++ + C+GL L R G KP L A P +V+ +G VTLRC + L
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 61 YKEDRIHVPIFHGRIFQE-----GFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVI 115
Y+E + ++ RI QE F + +T HAG Y C + G S S+P+ +
Sbjct: 61 YREKK--TALWITRIPQELVKKGQFPIPSITWEHAGRYRCY--YGSDTAGRSESSDPLEL 116
Query: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHD-G 174
+VTG + KP+L A P P+V SG VILQC S + F+ F L KE + P L Q H G
Sbjct: 117 VVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARG 176
Query: 175 VSKANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKV 234
S+A FS+G + + YRCY +++PY+ S PSD L+++V G+ +KPSLS QPGP V
Sbjct: 177 SSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIV 236
Query: 235 QAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPA--THGGTYR 292
E++TL C S + Y+ + L ++G +L + QA+F LGP ++GG YR
Sbjct: 237 APEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYR 296
Query: 293 CFGSFRHSPYEWSDPSDPLLVSVTGN-----PSSSWPSPTEPSSKSGNL 336
C+G+ S EWS PSDPL + + G S P PT S ++ L
Sbjct: 297 CYGAHNLSS-EWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTL 344
Score = 134 bits (338), Expect = 1e-31
Identities = 84/216 (38%), Positives = 114/216 (52%), Gaps = 8/216 (3%)
Query: 23 MGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHVPIFHGR-----IFQ 77
+G KP LS P +V +TL+C +N F+LYK+ G + Q
Sbjct: 220 LGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQ 279
Query: 78 EGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGN-HRKPSLLAHPGPLVKS 136
F + PV+ ++ G Y C G+H S + WSAPS+P+ I++ G + + SL PGP V S
Sbjct: 280 ANFTLGPVSRSYGGQYRCYGAHNLS-SEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVAS 338
Query: 137 GERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCY 196
GE V L C S + F L KE + DP RL +A F +G + A AGTYRCY
Sbjct: 339 GENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCY 398
Query: 197 GSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGP 232
GS + PY L+ PSDPL++VV+G PS S GP
Sbjct: 399 GSQSSKPYLLTHPSDPLELVVSGPSGGPS-SPTTGP 433
>gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 1 [Homo sapiens]
Length = 650
Score = 220 bits (560), Expect = 2e-57
Identities = 145/381 (38%), Positives = 208/381 (54%), Gaps = 37/381 (9%)
Query: 24 GGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKE-DRIHVPIFHGRIFQEG--- 79
G KP LSA PS VV GG+V L+C + F+ F L KE + H + + G
Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179
Query: 80 --FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSG 137
F++ PV+ + Y C +SP WS PS+ + ++V G +KPSL PGP+V
Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239
Query: 138 ERVILQCWSDIMFEHFFLHKEWISKDPSRLVG-QIHDGVSKANFSIGSMMRALAGTYRCY 196
E + LQC SD + F L+K+ +D +L G Q G+S+ANF++G + R+ G YRCY
Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDG-ERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCY 298
Query: 197 GSVTHTPYQLSAPSDPLDIVVTG-LYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHL 255
G+ + + SAPSDPLDI++ G Y++ SLS QPGP V +GE+VTL C S+ + L
Sbjct: 299 GA-HNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLL 357
Query: 256 SREGGAHERRLPAVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEWSDPSDPLLV 313
++EG A + ++ +QA+FP+GP T H GTYRC+GS PY + PSDPL +
Sbjct: 358 TKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLEL 417
Query: 314 SV---TGNPSSSWPSPTEPSS-------------KSGNLRHLHILIG--TSVVKIPFTIL 355
V +G PSS PT S +SG RHL ++IG +V+ + +L
Sbjct: 418 VVSGPSGGPSSPTTGPTSTSGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVILLLLLLL 477
Query: 356 LFFLLHR-------WCSNKKK 369
L FL+ R W S ++K
Sbjct: 478 LLFLILRHRRQGKHWTSTQRK 498
Score = 198 bits (503), Expect = 8e-51
Identities = 130/349 (37%), Positives = 186/349 (53%), Gaps = 18/349 (5%)
Query: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
M ++ + C+GL L R G KP L A P +V+ +G VTLRC + L
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 61 YKEDRIHVPIFHGRIFQE-----GFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVI 115
Y+E + ++ RI QE F + +T HAG Y C + G S S+P+ +
Sbjct: 61 YREKK--TALWITRIPQELVKKGQFPIPSITWEHAGRYRCY--YGSDTAGRSESSDPLEL 116
Query: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHD-G 174
+VTG + KP+L A P P+V SG VILQC S + F+ F L KE + P L Q H G
Sbjct: 117 VVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARG 176
Query: 175 VSKANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKV 234
S+A FS+G + + YRCY +++PY+ S PSD L+++V G+ +KPSLS QPGP V
Sbjct: 177 SSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIV 236
Query: 235 QAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPA--THGGTYR 292
E++TL C S + Y+ + L ++G +L + QA+F LGP ++GG YR
Sbjct: 237 APEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYR 296
Query: 293 CFGSFRHSPYEWSDPSDPLLVSVTGN-----PSSSWPSPTEPSSKSGNL 336
C+G+ S EWS PSDPL + + G S P PT S ++ L
Sbjct: 297 CYGAHNLSS-EWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTL 344
Score = 135 bits (341), Expect = 5e-32
Identities = 85/221 (38%), Positives = 116/221 (52%), Gaps = 8/221 (3%)
Query: 23 MGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHVPIFHGR-----IFQ 77
+G KP LS P +V +TL+C +N F+LYK+ G + Q
Sbjct: 220 LGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQ 279
Query: 78 EGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGN-HRKPSLLAHPGPLVKS 136
F + PV+ ++ G Y C G+H S + WSAPS+P+ I++ G + + SL PGP V S
Sbjct: 280 ANFTLGPVSRSYGGQYRCYGAHNLS-SEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVAS 338
Query: 137 GERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCY 196
GE V L C S + F L KE + DP RL +A F +G + A AGTYRCY
Sbjct: 339 GENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCY 398
Query: 197 GSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAG 237
GS + PY L+ PSDPL++VV+G PS S GP +G
Sbjct: 399 GSQSSKPYLLTHPSDPLELVVSGPSGGPS-SPTTGPTSTSG 438
>gi|31543056 leukocyte immunoglobulin-like receptor, subfamily A
(without TM domain), member 3 [Homo sapiens]
Length = 439
Score = 218 bits (554), Expect = 9e-57
Identities = 123/320 (38%), Positives = 182/320 (56%), Gaps = 10/320 (3%)
Query: 24 GGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKE-DRIHVPIFHGRIFQEG--- 79
G KP LSA PS VV GG+VT++C + F+ F+L KE + H + G
Sbjct: 120 GAYSKPTLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSR 179
Query: 80 --FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSG 137
F++ PV+ + +Y C G +P WS PS+ + ++V G +KPSL PGP+V G
Sbjct: 180 AIFSVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPG 239
Query: 138 ERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYG 197
E++ QC SD ++ F L+KEW R Q G+S+ANF++G + R+ G Y C G
Sbjct: 240 EKLTFQCGSDAGYDRFVLYKEWGRDFLQRPGRQPQAGLSQANFTLGPVSRSYGGQYTCSG 299
Query: 198 SVTHTPYQLSAPSDPLDIVVTG-LYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLS 256
+ + + SAPSDPLDI++TG + +P LS +PGP V +GE+VTL C S+ + L+
Sbjct: 300 AY-NLSSEWSAPSDPLDILITGQIRARPFLSVRPGPTVASGENVTLLCQSQGGMHTFLLT 358
Query: 257 REGGAHERRLPAVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEWSDPSDPLLVS 314
+EG A ++ + +QA+FP+ P T H GTYRC+GS +PY + PSDPL +
Sbjct: 359 KEGAADSPLRLKSKRQSHKYQAEFPMSPVTSAHAGTYRCYGSLSSNPYLLTHPSDPLELV 418
Query: 315 VTGNPSSSWPSPTEPSSKSG 334
V+G + P + SK+G
Sbjct: 419 VSGAAETLSPPQNKSDSKAG 438
Score = 198 bits (503), Expect = 8e-51
Identities = 133/350 (38%), Positives = 183/350 (52%), Gaps = 20/350 (5%)
Query: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
M ++ + C+GL L R G KP L A P +V+ +G VTLRC + L
Sbjct: 1 MTSILTVLICLGLSLDPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHL 60
Query: 61 YKEDRIHVPIFHGRIFQE-----GFNMSPVTTAHAGNYTC-RGSHPHSPTGWSAPSNPMV 114
Y+E + ++ RI QE F + +T HAG Y C GSH G S S+P+
Sbjct: 61 YREKK--TALWITRIPQELVKKGQFPILSITWEHAGRYCCIYGSHT---VGLSESSDPLE 115
Query: 115 IMVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIH-D 173
++VTG + KP+L A P P+V SG V +QC S + F+ F L KE + P L H
Sbjct: 116 LVVTGAYSKPTLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHAR 175
Query: 174 GVSKANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPK 233
G S+A FS+G + + +YRCYG + PY S PSD L ++V G+ +KPSLS QPGP
Sbjct: 176 GSSRAIFSVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPV 235
Query: 234 VQAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPA--THGGTY 291
V GE +T C S + YD + L +E G + P + QA+F LGP ++GG Y
Sbjct: 236 VAPGEKLTFQCGSDAGYDRFVLYKEWGRDFLQRPGRQPQAGLSQANFTLGPVSRSYGGQY 295
Query: 292 RCFGSFRHSPYEWSDPSDPLLVSVTGNPS-----SSWPSPTEPSSKSGNL 336
C G++ S EWS PSDPL + +TG S P PT S ++ L
Sbjct: 296 TCSGAYNLSS-EWSAPSDPLDILITGQIRARPFLSVRPGPTVASGENVTL 344
>gi|47519953 leukocyte immunoglobulin-like receptor subfamily A
member 4 [Homo sapiens]
Length = 499
Score = 216 bits (550), Expect = 3e-56
Identities = 130/317 (41%), Positives = 186/317 (58%), Gaps = 14/317 (4%)
Query: 28 KPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHVPIF-------HGRIFQEGF 80
+P LSA PS VV G +VTLRC R F L +E + HG+ FQ F
Sbjct: 122 RPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGK-FQALF 180
Query: 81 NMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSGERV 140
M P+T ++ G + C G ++P WS PS+P+ ++V+G RKPSLL GP+V GE +
Sbjct: 181 PMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGENL 240
Query: 141 ILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYGSVT 200
LQC SD+ + + L+KE P R Q G+S+ANF++ + R+ G YRCYG+
Sbjct: 241 TLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGA-H 299
Query: 201 HTPYQLSAPSDPLDIVVTG-LYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREG 259
+ + SAPSDPLDI++ G + ++PSLS QPGP V +GE VTL C S + L++EG
Sbjct: 300 NVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEG 359
Query: 260 GAH-ERRLPAVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEWSDPSDPLLVSVT 316
AH RL ++ ++ +QA+FP+ P T H GTYRC+GS +PY S PS+PL + V+
Sbjct: 360 AAHPPLRLRSMYGAHK-YQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVS 418
Query: 317 GNPSSSWPSPTEPSSKS 333
G + P+ + SK+
Sbjct: 419 GATETLNPAQKKSDSKT 435
Score = 164 bits (415), Expect = 1e-40
Identities = 120/347 (34%), Positives = 167/347 (48%), Gaps = 16/347 (4%)
Query: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
M L++ S+ GL L R KP L A P V+ VT+ C + L
Sbjct: 1 MTLILTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRL 60
Query: 61 YKEDRIHVPIFHGRIFQEG---FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMV 117
KE + E ++ + HAG Y C + SP GWS PS+P+ ++V
Sbjct: 61 DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHC---YYQSPAGWSEPSDPLELVV 117
Query: 118 TGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHD-GVS 176
T + +P+L A P P+V SG V L+C S + F L +E + L H+ G
Sbjct: 118 TA-YSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKF 176
Query: 177 KANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQA 236
+A F +G + + GT+RCYG +TPY S PSDPL ++V+G+ KPSL GP V
Sbjct: 177 QALFPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTP 236
Query: 237 GESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPA--THGGTYRCF 294
GE++TL C S Y Y L +EG + P + QA+F L P ++GG YRC+
Sbjct: 237 GENLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCY 296
Query: 295 GSFRHSPYEWSDPSDPLLVSVTGNPS-----SSWPSPTEPSSKSGNL 336
G+ S EWS PSDPL + + G S S P PT S + L
Sbjct: 297 GAHNVSS-EWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTL 342
Score = 68.2 bits (165), Expect = 1e-11
Identities = 39/98 (39%), Positives = 50/98 (51%), Gaps = 5/98 (5%)
Query: 27 DKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHVPI-----FHGRIFQEGFN 81
D+P LS P V G VTL C F+L KE H P+ + +Q F
Sbjct: 322 DRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEGAAHPPLRLRSMYGAHKYQAEFP 381
Query: 82 MSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTG 119
MSPVT+AHAG Y C GS +P S PS P+ ++V+G
Sbjct: 382 MSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSG 419
Score = 58.5 bits (140), Expect = 1e-08
Identities = 39/118 (33%), Positives = 53/118 (44%), Gaps = 6/118 (5%)
Query: 223 KPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPL 282
KP L A+PGP + VT+ C Y L +EG + R + + + P
Sbjct: 28 KPILWAEPGPVITWHNPVTIWCQGTLEAQGYRLDKEGNSMSRHILKTLESENKVKLSIPS 87
Query: 283 GPATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVT--GNPS-SSWPSPTEPSSKSGNLR 337
H G Y C + SP WS+PSDPL + VT P+ S+ PSP S + LR
Sbjct: 88 MMWEHAGRYHC---YYQSPAGWSEPSDPLELVVTAYSRPTLSALPSPVVTSGVNVTLR 142
>gi|125987593 leukocyte immunoglobulin-like receptor, subfamily B,
member 5 isoform 3 [Homo sapiens]
Length = 491
Score = 211 bits (536), Expect = 1e-54
Identities = 143/387 (36%), Positives = 201/387 (51%), Gaps = 31/387 (8%)
Query: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
M L + + C+GL + R G KP L A P++V+ RG VTL C + L
Sbjct: 1 MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60
Query: 61 YKED-----RIHVPIFHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVI 115
KE + P+ G + F++ AG Y C + +P GWS PS+P+ +
Sbjct: 61 DKEGLPWARKRQNPLEPGA--KAKFHIPSTVYDSAGRYRC---YYETPAGWSEPSDPLEL 115
Query: 116 MVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGV 175
+ TG RKPSLL G +V G + LQC SD+ ++ F L+KE Q G+
Sbjct: 116 VATGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGL 175
Query: 176 SKANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLY-EKPSLSAQPGPKV 234
S+ANF++G + R+ G YRCYG+ +P + SAPSDPLDI++ GL + P+LS QPGPKV
Sbjct: 176 SQANFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKV 234
Query: 235 QAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPAT--HGGTYR 292
+GE+VTL C S D + L++EG AH + + QA+F + P T GGTYR
Sbjct: 235 ASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYR 294
Query: 293 CFGSFRHSPYEWSDPSDPLLVSVTG-------NPSSSWPSPTEPSS----------KSGN 335
C+ + R PY S PS P + V+G +P+ S P+P P +SG
Sbjct: 295 CYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGL 354
Query: 336 LRHLHILIGTSVVKIPFTILLFFLLHR 362
RHL ++ G SV + LL FLL R
Sbjct: 355 GRHLGVVTGVSVAFVLLLFLLLFLLLR 381
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.447
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,826,133
Number of Sequences: 37866
Number of extensions: 920228
Number of successful extensions: 3502
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 75
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 2530
Number of HSP's gapped (non-prelim): 276
length of query: 382
length of database: 18,247,518
effective HSP length: 104
effective length of query: 278
effective length of database: 14,309,454
effective search space: 3978028212
effective search space used: 3978028212
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.