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Search of human proteins with 55956892
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55956892 kelch/ankyrin repeat containing cyclin A1
interacting protein isoform c [Homo sapiens]
(111 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55956892 kelch/ankyrin repeat containing cyclin A1 interactin... 241 9e-65
gi|55956888 kelch/ankyrin repeat containing cyclin A1 interactin... 241 9e-65
gi|7657301 kelch domain containing 2 [Homo sapiens] 34 0.022
gi|16945972 kelch domain containing 3 [Homo sapiens] 33 0.038
gi|46410931 attractin-like 1 [Homo sapiens] 32 0.084
gi|31542246 kelch-like 36 [Homo sapiens] 32 0.084
gi|21450863 attractin isoform 2 [Homo sapiens] 32 0.14
gi|21450861 attractin isoform 1 [Homo sapiens] 32 0.14
gi|21314675 kelch domain containing 4 [Homo sapiens] 31 0.24
gi|47717139 leucine-zipper-like transcription regulator 1 [Homo ... 30 0.42
gi|145701025 multiple EGF-like-domains 8 [Homo sapiens] 29 0.71
gi|24308181 kelch-like 9 [Homo sapiens] 28 1.6
gi|55741643 kelch-like 14 [Homo sapiens] 28 1.6
gi|29029595 glutamate receptor KA1 precursor [Homo sapiens] 28 2.1
gi|14780904 kelch-like 1 protein [Homo sapiens] 28 2.1
gi|21362105 BTB/POZ KELCH domain protein [Homo sapiens] 27 2.7
gi|26190616 kelch domain containing 1 [Homo sapiens] 27 2.7
gi|224926824 SH2B adaptor protein 1 isoform 2 [Homo sapiens] 27 3.5
gi|158508542 kelch-like 33 [Homo sapiens] 27 3.5
gi|224926830 SH2B adaptor protein 1 isoform 3 [Homo sapiens] 27 3.5
gi|224926828 SH2B adaptor protein 1 isoform 2 [Homo sapiens] 27 3.5
gi|224926826 SH2B adaptor protein 1 isoform 1 [Homo sapiens] 27 3.5
gi|224926822 SH2B adaptor protein 1 isoform 2 [Homo sapiens] 27 3.5
gi|226442729 kelch-like 15 [Homo sapiens] 27 4.6
gi|11056006 kelch-like 12 [Homo sapiens] 27 4.6
gi|40018614 DRE1 protein [Homo sapiens] 26 6.0
gi|69885084 p120E4F [Homo sapiens] 26 6.0
>gi|55956892 kelch/ankyrin repeat containing cyclin A1 interacting
protein isoform c [Homo sapiens]
Length = 111
Score = 241 bits (615), Expect = 9e-65
Identities = 111/111 (100%), Positives = 111/111 (100%)
Query: 1 MEQLARLVSSGQGSQKGPHGLRHHSCSVVGPFAVLFGGETLTRARDTICNDLYIYDTRTS 60
MEQLARLVSSGQGSQKGPHGLRHHSCSVVGPFAVLFGGETLTRARDTICNDLYIYDTRTS
Sbjct: 1 MEQLARLVSSGQGSQKGPHGLRHHSCSVVGPFAVLFGGETLTRARDTICNDLYIYDTRTS 60
Query: 61 PPLWFHFPCADRGMKRMGHRTCLWNDQLYLVGGFGEDGRTASPQVCILDFI 111
PPLWFHFPCADRGMKRMGHRTCLWNDQLYLVGGFGEDGRTASPQVCILDFI
Sbjct: 61 PPLWFHFPCADRGMKRMGHRTCLWNDQLYLVGGFGEDGRTASPQVCILDFI 111
>gi|55956888 kelch/ankyrin repeat containing cyclin A1 interacting
protein isoform a [Homo sapiens]
Length = 349
Score = 241 bits (615), Expect = 9e-65
Identities = 111/111 (100%), Positives = 111/111 (100%)
Query: 1 MEQLARLVSSGQGSQKGPHGLRHHSCSVVGPFAVLFGGETLTRARDTICNDLYIYDTRTS 60
MEQLARLVSSGQGSQKGPHGLRHHSCSVVGPFAVLFGGETLTRARDTICNDLYIYDTRTS
Sbjct: 239 MEQLARLVSSGQGSQKGPHGLRHHSCSVVGPFAVLFGGETLTRARDTICNDLYIYDTRTS 298
Query: 61 PPLWFHFPCADRGMKRMGHRTCLWNDQLYLVGGFGEDGRTASPQVCILDFI 111
PPLWFHFPCADRGMKRMGHRTCLWNDQLYLVGGFGEDGRTASPQVCILDFI
Sbjct: 299 PPLWFHFPCADRGMKRMGHRTCLWNDQLYLVGGFGEDGRTASPQVCILDFI 349
>gi|7657301 kelch domain containing 2 [Homo sapiens]
Length = 406
Score = 34.3 bits (77), Expect = 0.022
Identities = 28/91 (30%), Positives = 40/91 (43%), Gaps = 12/91 (13%)
Query: 16 KGPHGLRHHSCSVVGPFAVLFGGETLTRARDTICNDLYIYDTRTSPPLWFHFPCADRGMK 75
K P H+C+ VG +FGG R RD NDL+ + T W +G+
Sbjct: 213 KAPSPRAAHACATVGNRGFVFGG----RYRDARMNDLHYLNLDT----WEWNELIPQGIC 264
Query: 76 RMGHR----TCLWNDQLYLVGGFGEDGRTAS 102
+G T + +D L+L GGF D + S
Sbjct: 265 PVGRSWHSLTPVSSDHLFLFGGFTTDKQPLS 295
>gi|16945972 kelch domain containing 3 [Homo sapiens]
Length = 382
Score = 33.5 bits (75), Expect = 0.038
Identities = 23/81 (28%), Positives = 35/81 (43%), Gaps = 16/81 (19%)
Query: 24 HSCSVVGPFAVLFGGET-----LTRARDTICNDLYIYDTRTS-----PPLWFHFPCADRG 73
HS +++G +FGG + CN + ++DTRT PP P G
Sbjct: 183 HSATMLGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLDCPPT----PVLPEG 238
Query: 74 MKRMGHRTCLWNDQLYLVGGF 94
R H +N +LY+ GG+
Sbjct: 239 --RRSHSAFGYNGELYIFGGY 257
Score = 32.3 bits (72), Expect = 0.084
Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 8/88 (9%)
Query: 24 HSCSVVGPFAVLFGGETLTRARDTICNDLYIYDTRTSPPLWFHFPCADRGMK--RMGHRT 81
HS ++ +L+GG T CN LY +D T WF P + R GH
Sbjct: 80 HSTVLIDDTVLLWGGRNDTEGA---CNVLYAFDVNTHK--WFT-PRVSGTVPGARDGHSA 133
Query: 82 CLWNDQLYLVGGFGEDGRTASPQVCILD 109
C+ +Y+ GG+ + S + LD
Sbjct: 134 CVLGKIMYIFGGYEQQADCFSNDIHKLD 161
Score = 26.6 bits (57), Expect = 4.6
Identities = 12/23 (52%), Positives = 13/23 (56%)
Query: 16 KGPHGLRHHSCSVVGPFAVLFGG 38
KGP R C +VG VLFGG
Sbjct: 286 KGPCPRRRQCCCIVGDKIVLFGG 308
>gi|46410931 attractin-like 1 [Homo sapiens]
Length = 1379
Score = 32.3 bits (72), Expect = 0.084
Identities = 20/76 (26%), Positives = 29/76 (38%), Gaps = 5/76 (6%)
Query: 24 HSCSVVGPFAVLFGGET-----LTRARDTICNDLYIYDTRTSPPLWFHFPCADRGMKRMG 78
HS ++ ++FGG T L+ D YD P R + R G
Sbjct: 524 HSAVLINGAMLIFGGNTHNDTSLSNGAKCFSADFLAYDIACDEWKILPKPNLHRDVNRFG 583
Query: 79 HRTCLWNDQLYLVGGF 94
H + N +Y+ GGF
Sbjct: 584 HSAVVINGSMYIFGGF 599
>gi|31542246 kelch-like 36 [Homo sapiens]
Length = 616
Score = 32.3 bits (72), Expect = 0.084
Identities = 24/81 (29%), Positives = 33/81 (40%), Gaps = 5/81 (6%)
Query: 23 HHSCSVVGPFAVLFGGE-TLTRARDTICNDLYIYDTRTSPPLWFHFPCADRGMKRMGHRT 81
HH +V+G F + GG + D N LY YD R W A +R+
Sbjct: 337 HHCVAVLGGFIFIAGGSFSRDNGGDAASNLLYRYDPRCKQ--W--IKVASMNQRRVDFYL 392
Query: 82 CLWNDQLYLVGGFGEDGRTAS 102
D L +GG E+G +S
Sbjct: 393 ASIEDMLVAIGGRNENGALSS 413
>gi|21450863 attractin isoform 2 [Homo sapiens]
Length = 1272
Score = 31.6 bits (70), Expect = 0.14
Identities = 21/78 (26%), Positives = 31/78 (39%), Gaps = 9/78 (11%)
Query: 24 HSCSVVGPFAVLFGGET-----LTRARDTICNDLYIYDTRTSPPLWFHFPCAD--RGMKR 76
H+ +V ++FGG T ++ +D YD W P D + R
Sbjct: 557 HTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDR--WSVLPRPDLHHDVNR 614
Query: 77 MGHRTCLWNDQLYLVGGF 94
GH L N +Y+ GGF
Sbjct: 615 FGHSAVLHNSTMYVFGGF 632
>gi|21450861 attractin isoform 1 [Homo sapiens]
Length = 1429
Score = 31.6 bits (70), Expect = 0.14
Identities = 21/78 (26%), Positives = 31/78 (39%), Gaps = 9/78 (11%)
Query: 24 HSCSVVGPFAVLFGGET-----LTRARDTICNDLYIYDTRTSPPLWFHFPCAD--RGMKR 76
H+ +V ++FGG T ++ +D YD W P D + R
Sbjct: 557 HTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDR--WSVLPRPDLHHDVNR 614
Query: 77 MGHRTCLWNDQLYLVGGF 94
GH L N +Y+ GGF
Sbjct: 615 FGHSAVLHNSTMYVFGGF 632
>gi|21314675 kelch domain containing 4 [Homo sapiens]
Length = 520
Score = 30.8 bits (68), Expect = 0.24
Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 5/63 (7%)
Query: 34 VLFGGETLTRARDTICNDLYIYDTRTSPPLWFHFPCADRGMKRMGHRTCL---WNDQLYL 90
+LFGGE + + N+LY+Y+TR W +R H+ + QL++
Sbjct: 79 ILFGGEYFNGQKTFLYNELYVYNTRKD--TWTKVDIPSPPPRRCAHQAVVVPQGGGQLWV 136
Query: 91 VGG 93
GG
Sbjct: 137 FGG 139
Score = 30.0 bits (66), Expect = 0.42
Identities = 18/65 (27%), Positives = 25/65 (38%)
Query: 35 LFGGETLTRARDTICNDLYIYDTRTSPPLWFHFPCADRGMKRMGHRTCLWNDQLYLVGGF 94
+FGGE + + + ++ + W R GHR W QL L GGF
Sbjct: 136 VFGGEFASPNGEQFYHYKDLWVLHLATKTWEQVKSTGGPSGRSGHRMVAWKRQLILFGGF 195
Query: 95 GEDGR 99
E R
Sbjct: 196 HESTR 200
>gi|47717139 leucine-zipper-like transcription regulator 1 [Homo
sapiens]
Length = 840
Score = 30.0 bits (66), Expect = 0.42
Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 6/81 (7%)
Query: 23 HHSCSVVGPFAVLFGGET---LTRARDTICNDLYIYDTRTSPPLWFHFPCADR-GMKRMG 78
HHS V G +FGG T + + NDL+ Y T W + R + R
Sbjct: 120 HHSAVVYGSSMFVFGGYTGDIYSNSNLKNKNDLFEYKFATGQ--WTEWKIEGRLPVARSA 177
Query: 79 HRTCLWNDQLYLVGGFGEDGR 99
H +++D+L++ G+ + R
Sbjct: 178 HGATVYSDKLWIFAGYDGNAR 198
>gi|145701025 multiple EGF-like-domains 8 [Homo sapiens]
Length = 2778
Score = 29.3 bits (64), Expect = 0.71
Identities = 12/39 (30%), Positives = 21/39 (53%)
Query: 11 GQGSQKGPHGLRHHSCSVVGPFAVLFGGETLTRARDTIC 49
G+ +GP H+ SV+G + V++GG T ++ C
Sbjct: 438 GRDGLQGPRERAFHTASVLGNYMVVYGGNVHTHYQEEKC 476
>gi|24308181 kelch-like 9 [Homo sapiens]
Length = 617
Score = 28.1 bits (61), Expect = 1.6
Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 8/70 (11%)
Query: 24 HSCSVVGPFAVLFGGETLTRARDTICNDLYIYDTRTSPPLWFHFPCADRGMKRMGHRTCL 83
H+ +V G + GG T DT N+L +D T + RG+ H C
Sbjct: 439 HAGTVYGGLMYISGGIT----HDTFQNELMCFDPDTDKWMQKAPMTTVRGL----HCMCT 490
Query: 84 WNDQLYLVGG 93
D+LY++GG
Sbjct: 491 VGDKLYVIGG 500
>gi|55741643 kelch-like 14 [Homo sapiens]
Length = 628
Score = 28.1 bits (61), Expect = 1.6
Identities = 23/86 (26%), Positives = 32/86 (37%), Gaps = 5/86 (5%)
Query: 18 PHGLRHHSCSVVGPFAVLFGGETLTRARDT-ICNDLYIYDTRTSPPLWFHFPCADRGMKR 76
P+ HH V F + GGE N + YD R + W P +R
Sbjct: 359 PYNSAHHCVVEVENFLFVLGGEDQWNPNGKHSTNFVSRYDPRFNS--WIQLPPMQE--RR 414
Query: 77 MGHRTCLWNDQLYLVGGFGEDGRTAS 102
C + LY++GG E G +S
Sbjct: 415 ASFYACRLDKHLYVIGGRNETGYLSS 440
>gi|29029595 glutamate receptor KA1 precursor [Homo sapiens]
Length = 956
Score = 27.7 bits (60), Expect = 2.1
Identities = 15/48 (31%), Positives = 24/48 (50%), Gaps = 1/48 (2%)
Query: 58 RTSPPLWFH-FPCADRGMKRMGHRTCLWNDQLYLVGGFGEDGRTASPQ 104
R +P W+ PCA + ++ L N + VGGF + G T +P+
Sbjct: 567 RLTPYEWYSPHPCAQGRCNLLVNQYSLGNSLWFPVGGFMQQGSTIAPR 614
>gi|14780904 kelch-like 1 protein [Homo sapiens]
Length = 748
Score = 27.7 bits (60), Expect = 2.1
Identities = 19/52 (36%), Positives = 23/52 (44%), Gaps = 2/52 (3%)
Query: 49 CNDLYIYDTRTSPPLWFHFPCADRGMKRMGHRTCLWNDQLYLVGGFGEDGRT 100
C+ L Y R P A M R CL D+LY VGG+ DG+T
Sbjct: 663 CSRLLDYVERYDPKTDTWTMVAPLSMPRDAVGVCLLGDRLYAVGGY--DGQT 712
>gi|21362105 BTB/POZ KELCH domain protein [Homo sapiens]
Length = 589
Score = 27.3 bits (59), Expect = 2.7
Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 9/77 (11%)
Query: 18 PHGLRHHSCSVVGPFAVLFGGETLTRARDTICNDLYIYDTRTSPPLWFHFPCADRGMKRM 77
P R+ + +V+G + GG+T A Y +D T+ W D KRM
Sbjct: 479 PQPWRYTAAAVLGSQIFIMGGDTEFTAASA-----YRFDCETNQ--WTRI--GDMTAKRM 529
Query: 78 GHRTCLWNDQLYLVGGF 94
++LY+VGG+
Sbjct: 530 SCHALASGNKLYVVGGY 546
>gi|26190616 kelch domain containing 1 [Homo sapiens]
Length = 406
Score = 27.3 bits (59), Expect = 2.7
Identities = 23/79 (29%), Positives = 34/79 (43%), Gaps = 13/79 (16%)
Query: 24 HSCSVVGPFAVLFGGETLTRARDTICNDLYIYDTRTSPPLWFHFPCADRGMKRMGHR--- 80
H+C+V+G +FGG L T NDL+ + T W + HR
Sbjct: 200 HTCAVLGNKGYIFGGRVL----QTRMNDLHYLNLDT----WTWSGRITINGESPKHRSWH 251
Query: 81 --TCLWNDQLYLVGGFGED 97
T + +D+L+L GG D
Sbjct: 252 TLTPIADDKLFLCGGLSAD 270
>gi|224926824 SH2B adaptor protein 1 isoform 2 [Homo sapiens]
Length = 671
Score = 26.9 bits (58), Expect = 3.5
Identities = 12/23 (52%), Positives = 14/23 (60%)
Query: 13 GSQKGPHGLRHHSCSVVGPFAVL 35
G++ PH L SC V GP AVL
Sbjct: 98 GAEISPHDLSLESCRVGGPLAVL 120
>gi|158508542 kelch-like 33 [Homo sapiens]
Length = 453
Score = 26.9 bits (58), Expect = 3.5
Identities = 15/42 (35%), Positives = 19/42 (45%), Gaps = 3/42 (7%)
Query: 55 YDTRTSPPLWFHFPCADRGMKRMGHRTCLWNDQLYLVGGFGE 96
YD + P F P G+ R GH +LY+ GG GE
Sbjct: 310 YDPKLEKPGTFLSPM---GVPRAGHVMAALGGRLYVAGGLGE 348
>gi|224926830 SH2B adaptor protein 1 isoform 3 [Homo sapiens]
Length = 683
Score = 26.9 bits (58), Expect = 3.5
Identities = 12/23 (52%), Positives = 14/23 (60%)
Query: 13 GSQKGPHGLRHHSCSVVGPFAVL 35
G++ PH L SC V GP AVL
Sbjct: 98 GAEISPHDLSLESCRVGGPLAVL 120
>gi|224926828 SH2B adaptor protein 1 isoform 2 [Homo sapiens]
Length = 671
Score = 26.9 bits (58), Expect = 3.5
Identities = 12/23 (52%), Positives = 14/23 (60%)
Query: 13 GSQKGPHGLRHHSCSVVGPFAVL 35
G++ PH L SC V GP AVL
Sbjct: 98 GAEISPHDLSLESCRVGGPLAVL 120
>gi|224926826 SH2B adaptor protein 1 isoform 1 [Homo sapiens]
Length = 756
Score = 26.9 bits (58), Expect = 3.5
Identities = 12/23 (52%), Positives = 14/23 (60%)
Query: 13 GSQKGPHGLRHHSCSVVGPFAVL 35
G++ PH L SC V GP AVL
Sbjct: 98 GAEISPHDLSLESCRVGGPLAVL 120
>gi|224926822 SH2B adaptor protein 1 isoform 2 [Homo sapiens]
Length = 671
Score = 26.9 bits (58), Expect = 3.5
Identities = 12/23 (52%), Positives = 14/23 (60%)
Query: 13 GSQKGPHGLRHHSCSVVGPFAVL 35
G++ PH L SC V GP AVL
Sbjct: 98 GAEISPHDLSLESCRVGGPLAVL 120
>gi|226442729 kelch-like 15 [Homo sapiens]
Length = 604
Score = 26.6 bits (57), Expect = 4.6
Identities = 11/36 (30%), Positives = 20/36 (55%), Gaps = 2/36 (5%)
Query: 74 MKRMGHRTCLWNDQLYLVGGFGEDGRTASPQVCILD 109
+ + GH + N++L++ GG + S QVC+ D
Sbjct: 414 VNKYGHEGTVLNNKLFITGGI--TSSSTSKQVCVFD 447
>gi|11056006 kelch-like 12 [Homo sapiens]
Length = 568
Score = 26.6 bits (57), Expect = 4.6
Identities = 11/20 (55%), Positives = 13/20 (65%)
Query: 75 KRMGHRTCLWNDQLYLVGGF 94
KR G L ND +Y+VGGF
Sbjct: 462 KRSGAGVALLNDHIYVVGGF 481
Score = 26.2 bits (56), Expect = 6.0
Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 6/56 (10%)
Query: 55 YDTRTSPPLWFHFPCADRGMKRMGHRTCLWNDQLYLVGGFGEDGRTASPQVCILDF 110
YD +T W P R KR + +D++Y++GG+ DGR+ V LD+
Sbjct: 302 YDPKTQE--WSFLPSITR--KRRYVASVSLHDRIYVIGGY--DGRSRLSSVECLDY 351
>gi|40018614 DRE1 protein [Homo sapiens]
Length = 600
Score = 26.2 bits (56), Expect = 6.0
Identities = 13/52 (25%), Positives = 29/52 (55%), Gaps = 4/52 (7%)
Query: 51 DLYIYDTRTSPPLWFHFPCADRGMKRMGHRTCLWNDQLYLVGGFGEDGRTAS 102
D++IY+++ + +W ++G R H+ + ++Y+VGG+ R +S
Sbjct: 376 DVWIYNSQLN--IWIRVASLNKG--RWRHKMAVLLGKVYVVGGYDGQNRLSS 423
>gi|69885084 p120E4F [Homo sapiens]
Length = 784
Score = 26.2 bits (56), Expect = 6.0
Identities = 23/96 (23%), Positives = 38/96 (39%), Gaps = 10/96 (10%)
Query: 13 GSQKGPHGLRHHSCSVVG-PFAVLFGGETLTRARDTICNDLYIYDTRTS---------PP 62
GS G GL + SV G P +T A+ T+ +++++ S PP
Sbjct: 295 GSGAGAAGLGTATSSVTGEPIETSPVIHLVTDAKGTVIHEVHVQMQELSLGMKALAPEPP 354
Query: 63 LWFHFPCADRGMKRMGHRTCLWNDQLYLVGGFGEDG 98
+ PC+ G + + N + L GE+G
Sbjct: 355 VSQELPCSSEGSRENLLHQAMQNSGIVLERAAGEEG 390
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.142 0.477
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,916,722
Number of Sequences: 37866
Number of extensions: 196530
Number of successful extensions: 478
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 452
Number of HSP's gapped (non-prelim): 43
length of query: 111
length of database: 18,247,518
effective HSP length: 81
effective length of query: 30
effective length of database: 15,180,372
effective search space: 455411160
effective search space used: 455411160
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.