BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|55749998 deiodinase, iodothyronine, type II isoform b [Homo sapiens] (309 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|55749998 deiodinase, iodothyronine, type II isoform b [Homo s... 617 e-177 gi|7549803 deiodinase, iodothyronine, type II isoform a [Homo sa... 526 e-149 gi|7549805 deiodinase, iodothyronine, type II isoform a [Homo sa... 526 e-149 gi|4557522 deiodinase, iodothyronine, type I isoform a [Homo sap... 140 2e-33 gi|55750011 deiodinase, iodothyronine, type III [Homo sapiens] 139 3e-33 gi|47132603 deiodinase, iodothyronine, type I isoform b [Homo sa... 131 9e-31 gi|89357938 deiodinase, iodothyronine, type I isoform d [Homo sa... 72 5e-13 gi|89357935 deiodinase, iodothyronine, type I isoform c [Homo sa... 72 5e-13 gi|55743114 leucine rich repeat containing 49 [Homo sapiens] 32 0.71 gi|169162069 PREDICTED: hypothetical protein [Homo sapiens] 31 1.6 gi|169162780 PREDICTED: hypothetical protein [Homo sapiens] 31 1.6 gi|52627199 olfactory receptor, family 4, subfamily C, member 15... 31 1.6 gi|55749600 spire homolog 2 [Homo sapiens] 30 3.5 gi|21361831 partitioning-defective protein 3 homolog [Homo sapiens] 29 4.6 gi|39780588 TSR1, 20S rRNA accumulation [Homo sapiens] 29 4.6 gi|18860918 xylulokinase [Homo sapiens] 28 7.9 gi|122937516 aldo-keto reductase family 1, member B10-like [Homo... 28 7.9 >gi|55749998 deiodinase, iodothyronine, type II isoform b [Homo sapiens] Length = 309 Score = 617 bits (1592), Expect = e-177 Identities = 309/309 (100%), Positives = 309/309 (100%) Query: 1 MGILSVDLLITLQILPVFFSNCLFLALYDSVILLKHVVLLLSRSKSTRGEWRRMLTSEGL 60 MGILSVDLLITLQILPVFFSNCLFLALYDSVILLKHVVLLLSRSKSTRGEWRRMLTSEGL Sbjct: 1 MGILSVDLLITLQILPVFFSNCLFLALYDSVILLKHVVLLLSRSKSTRGEWRRMLTSEGL 60 Query: 61 RCVWKSFLLDAYKQLNCPPSGFSKDGHILULVYEAYKSRLLVYSHLDLWMVKLGEDAPNS 120 RCVWKSFLLDAYKQLNCPPSGFSKDGHIL LVYEAYKSRLLVYSHLDLWMVKLGEDAPNS Sbjct: 61 RCVWKSFLLDAYKQLNCPPSGFSKDGHILULVYEAYKSRLLVYSHLDLWMVKLGEDAPNS 120 Query: 121 SVVHVSSTEGGDNSGNGTQEKIAEGATCHLLDFASPERPLVVNFGSATUPPFTSQLPAFR 180 SVVHVSSTEGGDNSGNGTQEKIAEGATCHLLDFASPERPLVVNFGSAT PPFTSQLPAFR Sbjct: 121 SVVHVSSTEGGDNSGNGTQEKIAEGATCHLLDFASPERPLVVNFGSATUPPFTSQLPAFR 180 Query: 181 KLVEEFSSVADFLLVYIDEAHPSDGWAIPGDSSLSFEVKKHQNQEDRCAAAQQLLERFSL 240 KLVEEFSSVADFLLVYIDEAHPSDGWAIPGDSSLSFEVKKHQNQEDRCAAAQQLLERFSL Sbjct: 181 KLVEEFSSVADFLLVYIDEAHPSDGWAIPGDSSLSFEVKKHQNQEDRCAAAQQLLERFSL 240 Query: 241 PPQCRVVADRMDNNANIAYGVAFERVCIVQRQKIAYLGGKGPFSYNLQEVRHWLEKNFSK 300 PPQCRVVADRMDNNANIAYGVAFERVCIVQRQKIAYLGGKGPFSYNLQEVRHWLEKNFSK Sbjct: 241 PPQCRVVADRMDNNANIAYGVAFERVCIVQRQKIAYLGGKGPFSYNLQEVRHWLEKNFSK 300 Query: 301 RUKKTRLAG 309 R KKTRLAG Sbjct: 301 RUKKTRLAG 309 >gi|7549803 deiodinase, iodothyronine, type II isoform a [Homo sapiens] Length = 273 Score = 526 bits (1354), Expect = e-149 Identities = 273/309 (88%), Positives = 273/309 (88%), Gaps = 36/309 (11%) Query: 1 MGILSVDLLITLQILPVFFSNCLFLALYDSVILLKHVVLLLSRSKSTRGEWRRMLTSEGL 60 MGILSVDLLITLQILPVFFSNCLFLALYDSVILLKHVVLLLSRSKSTRGEWRRMLTSEGL Sbjct: 1 MGILSVDLLITLQILPVFFSNCLFLALYDSVILLKHVVLLLSRSKSTRGEWRRMLTSEGL 60 Query: 61 RCVWKSFLLDAYKQLNCPPSGFSKDGHILULVYEAYKSRLLVYSHLDLWMVKLGEDAPNS 120 RCVWKSFLLDAYKQ VKLGEDAPNS Sbjct: 61 RCVWKSFLLDAYKQ------------------------------------VKLGEDAPNS 84 Query: 121 SVVHVSSTEGGDNSGNGTQEKIAEGATCHLLDFASPERPLVVNFGSATUPPFTSQLPAFR 180 SVVHVSSTEGGDNSGNGTQEKIAEGATCHLLDFASPERPLVVNFGSAT PPFTSQLPAFR Sbjct: 85 SVVHVSSTEGGDNSGNGTQEKIAEGATCHLLDFASPERPLVVNFGSATUPPFTSQLPAFR 144 Query: 181 KLVEEFSSVADFLLVYIDEAHPSDGWAIPGDSSLSFEVKKHQNQEDRCAAAQQLLERFSL 240 KLVEEFSSVADFLLVYIDEAHPSDGWAIPGDSSLSFEVKKHQNQEDRCAAAQQLLERFSL Sbjct: 145 KLVEEFSSVADFLLVYIDEAHPSDGWAIPGDSSLSFEVKKHQNQEDRCAAAQQLLERFSL 204 Query: 241 PPQCRVVADRMDNNANIAYGVAFERVCIVQRQKIAYLGGKGPFSYNLQEVRHWLEKNFSK 300 PPQCRVVADRMDNNANIAYGVAFERVCIVQRQKIAYLGGKGPFSYNLQEVRHWLEKNFSK Sbjct: 205 PPQCRVVADRMDNNANIAYGVAFERVCIVQRQKIAYLGGKGPFSYNLQEVRHWLEKNFSK 264 Query: 301 RUKKTRLAG 309 R KKTRLAG Sbjct: 265 RUKKTRLAG 273 >gi|7549805 deiodinase, iodothyronine, type II isoform a [Homo sapiens] Length = 273 Score = 526 bits (1354), Expect = e-149 Identities = 273/309 (88%), Positives = 273/309 (88%), Gaps = 36/309 (11%) Query: 1 MGILSVDLLITLQILPVFFSNCLFLALYDSVILLKHVVLLLSRSKSTRGEWRRMLTSEGL 60 MGILSVDLLITLQILPVFFSNCLFLALYDSVILLKHVVLLLSRSKSTRGEWRRMLTSEGL Sbjct: 1 MGILSVDLLITLQILPVFFSNCLFLALYDSVILLKHVVLLLSRSKSTRGEWRRMLTSEGL 60 Query: 61 RCVWKSFLLDAYKQLNCPPSGFSKDGHILULVYEAYKSRLLVYSHLDLWMVKLGEDAPNS 120 RCVWKSFLLDAYKQ VKLGEDAPNS Sbjct: 61 RCVWKSFLLDAYKQ------------------------------------VKLGEDAPNS 84 Query: 121 SVVHVSSTEGGDNSGNGTQEKIAEGATCHLLDFASPERPLVVNFGSATUPPFTSQLPAFR 180 SVVHVSSTEGGDNSGNGTQEKIAEGATCHLLDFASPERPLVVNFGSAT PPFTSQLPAFR Sbjct: 85 SVVHVSSTEGGDNSGNGTQEKIAEGATCHLLDFASPERPLVVNFGSATUPPFTSQLPAFR 144 Query: 181 KLVEEFSSVADFLLVYIDEAHPSDGWAIPGDSSLSFEVKKHQNQEDRCAAAQQLLERFSL 240 KLVEEFSSVADFLLVYIDEAHPSDGWAIPGDSSLSFEVKKHQNQEDRCAAAQQLLERFSL Sbjct: 145 KLVEEFSSVADFLLVYIDEAHPSDGWAIPGDSSLSFEVKKHQNQEDRCAAAQQLLERFSL 204 Query: 241 PPQCRVVADRMDNNANIAYGVAFERVCIVQRQKIAYLGGKGPFSYNLQEVRHWLEKNFSK 300 PPQCRVVADRMDNNANIAYGVAFERVCIVQRQKIAYLGGKGPFSYNLQEVRHWLEKNFSK Sbjct: 205 PPQCRVVADRMDNNANIAYGVAFERVCIVQRQKIAYLGGKGPFSYNLQEVRHWLEKNFSK 264 Query: 301 RUKKTRLAG 309 R KKTRLAG Sbjct: 265 RUKKTRLAG 273 >gi|4557522 deiodinase, iodothyronine, type I isoform a [Homo sapiens] Length = 249 Score = 140 bits (352), Expect = 2e-33 Identities = 79/185 (42%), Positives = 107/185 (57%), Gaps = 25/185 (13%) Query: 112 KLGEDAPNSSVVHVSSTEGGDNSGNGTQEKIAEGATCHLLDFASPERPLVVNFGSATUPP 171 +LG APN VV +S G C++ +F RPLV+NFGS T P Sbjct: 87 ELGGLAPNCPVVRLS------------------GQRCNIWEFMQGNRPLVLNFGSCTUPS 128 Query: 172 FTSQLPAFRKLVEEFSSVADFLLVYIDEAHPSDGWAIPGDSSLSFEVKKHQNQEDRCAAA 231 F + F++L+E+FSS+ADFL++YI+EAH SDGWA + +++ HQN +DR AA Sbjct: 129 FMFKFDQFKRLIEDFSSIADFLVIYIEEAHASDGWAFKN----NMDIRNHQNLQDRLQAA 184 Query: 232 QQLLERFSLPPQCRVVADRMDNNANIAYGVAFERVCIVQRQKIAYLGGKGPFSYNLQEVR 291 LL R PQC VV D M N ++ Y ER+ I+Q +I Y G GP++YN +EVR Sbjct: 185 HLLLAR---SPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYKGKSGPWNYNPEEVR 241 Query: 292 HWLEK 296 LEK Sbjct: 242 AVLEK 246 >gi|55750011 deiodinase, iodothyronine, type III [Homo sapiens] Length = 278 Score = 139 bits (350), Expect = 3e-33 Identities = 100/290 (34%), Positives = 144/290 (49%), Gaps = 49/290 (16%) Query: 12 LQILPVFFSNCLFLALYDSVILLKHVVLLLSRSKSTRGEWRRMLTSEGLRCVWKSFLLDA 71 L + P F L L D + + KH L R + + E L SEG Sbjct: 20 LVLFPRFLGTAFMLWLLDFLCIRKH---FLGRRRRGQPEPEVELNSEGEEV--------- 67 Query: 72 YKQLNCPPSGFSKDGHILUL-----VYEAYKSRLLVYSHLDLWMVKLGEDAPNSSVVHVS 126 + PP S D + L V+ K +H G APNS VV Sbjct: 68 --PPDDPPICVSDDNRLCTLASLKAVWHGQKLDFFKQAHE-------GGPAPNSEVV--- 115 Query: 127 STEGGDNSGNGTQEKIAEGATCHLLDFASPERPLVVNFGSATUPPFTSQLPAFRKLVEEF 186 +G Q + H+LD+A RPLV+NFGS T PPF +++ AF++LV ++ Sbjct: 116 -------LPDGFQSQ-------HILDYAQGNRPLVLNFGSCTUPPFMARMSAFQRLVTKY 161 Query: 187 SSVADFLLVYIDEAHPSDGWAIPGDSSLSFEVKKHQNQEDRCAAAQQLLERFSLPPQCRV 246 DFL++YI+EAHPSDGW + DS + + +H++ EDR +AA+ L + P C + Sbjct: 162 QRDVDFLIIYIEEAHPSDGW-VTTDS--PYIIPQHRSLEDRVSAARVLQQG---APGCAL 215 Query: 247 VADRMDNNANIAYGVAFERVCIVQRQKIAYLGGKGPFSYNLQEVRHWLEK 296 V D M N+++ AYG FER+ ++Q I Y GG+GP Y + E+R WLE+ Sbjct: 216 VLDTMANSSSSAYGAYFERLYVIQSGTIMYQGGRGPDGYQVSELRTWLER 265 >gi|47132603 deiodinase, iodothyronine, type I isoform b [Homo sapiens] Length = 185 Score = 131 bits (329), Expect = 9e-31 Identities = 68/139 (48%), Positives = 91/139 (65%), Gaps = 7/139 (5%) Query: 158 RPLVVNFGSATUPPFTSQLPAFRKLVEEFSSVADFLLVYIDEAHPSDGWAIPGDSSLSFE 217 RPLV+NFGS T P F + F++L+E+FSS+ADFL++YI+EAH SDGWA + + Sbjct: 51 RPLVLNFGSCTUPSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHASDGWAFKN----NMD 106 Query: 218 VKKHQNQEDRCAAAQQLLERFSLPPQCRVVADRMDNNANIAYGVAFERVCIVQRQKIAYL 277 ++ HQN +DR AA LL R PQC VV D M N ++ Y ER+ I+Q +I Y Sbjct: 107 IRNHQNLQDRLQAAHLLLAR---SPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYK 163 Query: 278 GGKGPFSYNLQEVRHWLEK 296 G GP++YN +EVR LEK Sbjct: 164 GKSGPWNYNPEEVRAVLEK 182 >gi|89357938 deiodinase, iodothyronine, type I isoform d [Homo sapiens] Length = 161 Score = 72.4 bits (176), Expect = 5e-13 Identities = 39/92 (42%), Positives = 54/92 (58%), Gaps = 18/92 (19%) Query: 112 KLGEDAPNSSVVHVSSTEGGDNSGNGTQEKIAEGATCHLLDFASPERPLVVNFGSATUPP 171 +LG APN VV +S G C++ +F RPLV+NFGS T P Sbjct: 87 ELGGLAPNCPVVRLS------------------GQRCNIWEFMQGNRPLVLNFGSCTUPS 128 Query: 172 FTSQLPAFRKLVEEFSSVADFLLVYIDEAHPS 203 F + F++L+E+FSS+ADFL++YI+EAH S Sbjct: 129 FMFKFDQFKRLIEDFSSIADFLVIYIEEAHAS 160 >gi|89357935 deiodinase, iodothyronine, type I isoform c [Homo sapiens] Length = 201 Score = 72.4 bits (176), Expect = 5e-13 Identities = 40/93 (43%), Positives = 53/93 (56%), Gaps = 7/93 (7%) Query: 204 DGWAIPGDSSLSFEVKKHQNQEDRCAAAQQLLERFSLPPQCRVVADRMDNNANIAYGVAF 263 DGWA + +++ HQN +DR AA LL R PQC VV D M N ++ Y Sbjct: 113 DGWAFKNN----MDIRNHQNLQDRLQAAHLLLAR---SPQCPVVVDTMQNQSSQLYAALP 165 Query: 264 ERVCIVQRQKIAYLGGKGPFSYNLQEVRHWLEK 296 ER+ I+Q +I Y G GP++YN +EVR LEK Sbjct: 166 ERLYIIQEGRILYKGKSGPWNYNPEEVRAVLEK 198 >gi|55743114 leucine rich repeat containing 49 [Homo sapiens] Length = 686 Score = 32.0 bits (71), Expect = 0.71 Identities = 16/62 (25%), Positives = 32/62 (51%) Query: 240 LPPQCRVVADRMDNNANIAYGVAFERVCIVQRQKIAYLGGKGPFSYNLQEVRHWLEKNFS 299 +P + R V+ R NN N + + + ++ K+ + K S+ + ++H LE+N+S Sbjct: 2 IPGKYRSVSGRAANNVNCGLHLVIQTSSLPEKNKVEFKLNKDTSSFPGRLLQHDLERNYS 61 Query: 300 KR 301 R Sbjct: 62 SR 63 >gi|169162069 PREDICTED: hypothetical protein [Homo sapiens] Length = 530 Score = 30.8 bits (68), Expect = 1.6 Identities = 21/68 (30%), Positives = 28/68 (41%), Gaps = 11/68 (16%) Query: 115 EDAPNSSVVHVSSTEGGDNSGNGTQEKIAEGATCHLLDFASPERPLVVNFGSATUPPFTS 174 +D SSV+ + S G +GT+ K SP P+ NF S PP TS Sbjct: 160 QDQGRSSVLKLISRRGRSTVNSGTKNKNN-----------SPLAPIFFNFHSLRNPPITS 208 Query: 175 QLPAFRKL 182 P R + Sbjct: 209 LAPTTRHI 216 >gi|169162780 PREDICTED: hypothetical protein [Homo sapiens] Length = 530 Score = 30.8 bits (68), Expect = 1.6 Identities = 21/68 (30%), Positives = 28/68 (41%), Gaps = 11/68 (16%) Query: 115 EDAPNSSVVHVSSTEGGDNSGNGTQEKIAEGATCHLLDFASPERPLVVNFGSATUPPFTS 174 +D SSV+ + S G +GT+ K SP P+ NF S PP TS Sbjct: 160 QDQGRSSVLKLISRRGRSTVNSGTKNKNN-----------SPLAPIFFNFHSLRNPPITS 208 Query: 175 QLPAFRKL 182 P R + Sbjct: 209 LAPTTRHI 216 >gi|52627199 olfactory receptor, family 4, subfamily C, member 15 [Homo sapiens] Length = 370 Score = 30.8 bits (68), Expect = 1.6 Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 1/57 (1%) Query: 30 SVILLKHVVLLLS-RSKSTRGEWRRMLTSEGLRCVWKSFLLDAYKQLNCPPSGFSKD 85 S++L+ + V+LLS R+ S+ G W+ + T V F + PPS FS D Sbjct: 265 SLLLVSYAVILLSLRTHSSEGRWKALSTCGSHIAVVILFFVPCIFVYTRPPSAFSLD 321 >gi|55749600 spire homolog 2 [Homo sapiens] Length = 714 Score = 29.6 bits (65), Expect = 3.5 Identities = 22/94 (23%), Positives = 37/94 (39%), Gaps = 3/94 (3%) Query: 154 ASPERPLVVNFGSATUPPFTSQLPAFRKLVEEFSSVADFLLVYIDEAHPSDGWAIPGDSS 213 + P PL+ N GS+ P S P + L EFS + L + ++E + + Sbjct: 495 SDPSHPLLSNRGSSGDRPEASMTPDAKHLWLEFSHPVESLALTVEEVMDVRRVLVKAEME 554 Query: 214 LSFEVKKHQNQEDR---CAAAQQLLERFSLPPQC 244 + K+ + + C + FS PP C Sbjct: 555 KFLQNKELFSSLKKGKICCCCRAKFPLFSWPPSC 588 >gi|21361831 partitioning-defective protein 3 homolog [Homo sapiens] Length = 1356 Score = 29.3 bits (64), Expect = 4.6 Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 10/82 (12%) Query: 210 GDSSLSFEVK-KHQNQEDRCAAAQQLLERFSLPPQCRVVADRMDNNA---NIAYGVAFE- 264 G S+S EV+ + Q QE+R ++ Q + SLP Q R A + ++ N + G F+ Sbjct: 1193 GRHSVSVEVQMQRQRQEERESSQQAQRQYSSLPRQSRKNASSVSQDSWEQNYSPGEGFQS 1252 Query: 265 -----RVCIVQRQKIAYLGGKG 281 R Q + YLGG G Sbjct: 1253 AKENPRYSSYQGSRNGYLGGHG 1274 >gi|39780588 TSR1, 20S rRNA accumulation [Homo sapiens] Length = 804 Score = 29.3 bits (64), Expect = 4.6 Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 3/44 (6%) Query: 172 FTSQLPAFRKLVEEFSSVADFLLVYIDEAHPSDGWAIPGDSSLS 215 FTS P +V + + VAD +L +D P +GW GD LS Sbjct: 135 FTSARPGDLHVVLDMAKVADTILFLLD---PLEGWDSTGDYCLS 175 >gi|18860918 xylulokinase [Homo sapiens] Length = 536 Score = 28.5 bits (62), Expect = 7.9 Identities = 12/30 (40%), Positives = 19/30 (63%) Query: 229 AAAQQLLERFSLPPQCRVVADRMDNNANIA 258 A + ++R+ PP C+VVA DN A++A Sbjct: 257 AISSYYVQRYGFPPGCKVVAFTGDNPASLA 286 >gi|122937516 aldo-keto reductase family 1, member B10-like [Homo sapiens] Length = 316 Score = 28.5 bits (62), Expect = 7.9 Identities = 40/178 (22%), Positives = 66/178 (37%), Gaps = 17/178 (9%) Query: 91 LVYEAYKSRL--LVYSHLDLWMVKLGEDAPNSSVVHVSSTEGGDNSGNGT--------QE 140 LV +A++ L L S+LD++++ + +G SG GT +E Sbjct: 88 LVRKAFEKTLKDLKLSYLDVYLIHWPQGFKTGDDFFPKDDKGNMISGKGTFLDAWEAMEE 147 Query: 141 KIAEGATCHL--LDFASPERPLVVNFGSATUPPFTSQLPAF-----RKLVEEFSSVADFL 193 + EG L +F + ++N P T+Q+ KL++ S + Sbjct: 148 LVDEGLVKALGVSNFNHFQIERLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITV 207 Query: 194 LVYIDEAHPSDGWAIPGDSSLSFEVKKHQNQEDRCAAAQQLLERFSLPPQCRVVADRM 251 Y P WA P D SL + K + Q+L RF + V+ M Sbjct: 208 TAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTTAQVLIRFHIQRNVTVIPKSM 265 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.136 0.413 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,830,232 Number of Sequences: 37866 Number of extensions: 508396 Number of successful extensions: 1181 Number of sequences better than 10.0: 17 Number of HSP's better than 10.0 without gapping: 10 Number of HSP's successfully gapped in prelim test: 7 Number of HSP's that attempted gapping in prelim test: 1160 Number of HSP's gapped (non-prelim): 17 length of query: 309 length of database: 18,247,518 effective HSP length: 102 effective length of query: 207 effective length of database: 14,385,186 effective search space: 2977733502 effective search space used: 2977733502 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.