Search of human proteins with 5453597

Search of human proteins with 5453597

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5453597 F-actin capping protein alpha-1 subunit [Homo
sapiens]
         (286 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5453597 F-actin capping protein alpha-1 subunit [Homo sapiens]     587   e-168
gi|5453599 capping protein (actin filament) muscle Z-line, alpha...   520   e-148
gi|15277417 capping protein alpha 3 [Homo sapiens]                    191   5e-49
gi|31377575 ENTH domain containing 1 [Homo sapiens]                    29   4.1  
gi|24308237 phosphatidylinositol transfer protein, membrane-asso...    29   5.4  
gi|55749769 CWC22 spliceosome-associated protein homolog [Homo s...    28   9.2  

>gi|5453597 F-actin capping protein alpha-1 subunit [Homo sapiens]
          Length = 286

 Score =  587 bits (1514), Expect = e-168
 Identities = 286/286 (100%), Positives = 286/286 (100%)

Query: 1   MADFDDRVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMD 60
           MADFDDRVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMD
Sbjct: 1   MADFDDRVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMD 60

Query: 61  QFTPVKIEGYEDQVLITEHGDLGNSRFLDPRNKISFKFDHLRKEASDPQPEEADGGLKSW 120
           QFTPVKIEGYEDQVLITEHGDLGNSRFLDPRNKISFKFDHLRKEASDPQPEEADGGLKSW
Sbjct: 61  QFTPVKIEGYEDQVLITEHGDLGNSRFLDPRNKISFKFDHLRKEASDPQPEEADGGLKSW 120

Query: 121 RESCDSALRAYVKDHYSNGFCTVYAKTIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFT 180
           RESCDSALRAYVKDHYSNGFCTVYAKTIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFT
Sbjct: 121 RESCDSALRAYVKDHYSNGFCTVYAKTIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFT 180

Query: 181 ITPPTAQVVGVLKIQVHYYEDGNVQLVSHKDVQDSLTVSNEAQTAKEFIKIIENAENEYQ 240
           ITPPTAQVVGVLKIQVHYYEDGNVQLVSHKDVQDSLTVSNEAQTAKEFIKIIENAENEYQ
Sbjct: 181 ITPPTAQVVGVLKIQVHYYEDGNVQLVSHKDVQDSLTVSNEAQTAKEFIKIIENAENEYQ 240

Query: 241 TAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA 286
           TAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA
Sbjct: 241 TAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA 286


>gi|5453599 capping protein (actin filament) muscle Z-line, alpha 2
           [Homo sapiens]
          Length = 286

 Score =  520 bits (1339), Expect = e-148
 Identities = 248/286 (86%), Positives = 267/286 (93%)

Query: 1   MADFDDRVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMD 60
           MAD ++++SDEEKVRIAAKFI HAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYN+D
Sbjct: 1   MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLD 60

Query: 61  QFTPVKIEGYEDQVLITEHGDLGNSRFLDPRNKISFKFDHLRKEASDPQPEEADGGLKSW 120
           QFTPVKIEGYEDQVLITEHGDLGN +FLDP+N+I FKFDHLRKEA+DP+P E +  ++SW
Sbjct: 61  QFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPCEVENAVESW 120

Query: 121 RESCDSALRAYVKDHYSNGFCTVYAKTIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFT 180
           R S ++ALRAYVK+HY NG CTVY K IDGQQTIIACIESHQFQ KNFWNGRWRSEWKFT
Sbjct: 121 RTSVETALRAYVKEHYPNGVCTVYGKKIDGQQTIIACIESHQFQAKNFWNGRWRSEWKFT 180

Query: 181 ITPPTAQVVGVLKIQVHYYEDGNVQLVSHKDVQDSLTVSNEAQTAKEFIKIIENAENEYQ 240
           ITP T QVVG+LKIQVHYYEDGNVQLVSHKD+QDSLTVSNE QTAKEFIKI+E AENEYQ
Sbjct: 181 ITPSTTQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQ 240

Query: 241 TAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA 286
           TAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA
Sbjct: 241 TAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA 286


>gi|15277417 capping protein alpha 3 [Homo sapiens]
          Length = 299

 Score =  191 bits (486), Expect = 5e-49
 Identities = 99/271 (36%), Positives = 158/271 (58%), Gaps = 4/271 (1%)

Query: 8   VSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKI 67
           +S ++K R+  + +  APPGEF   F+D+ LL+ ++ L+      A  Q+      P+ I
Sbjct: 6   LSRKDKERVIRRLLLQAPPGEFVNAFDDLCLLIRDEKLMHHQGECAGHQHCQKYSVPLCI 65

Query: 68  EGYEDQVLITEHGDLGNSRFLDPRNKISFKFDHLRKEASDPQPEEA-DGGLKSWRESCDS 126
           +G  + VL++ H  +G+ RF D ++K+SFK+D L+ +  D Q         +  R     
Sbjct: 66  DG--NPVLLSHHNVMGDYRFFDHQSKLSFKYDLLQNQLKDIQSHGIIQNEAEYLRVVLLC 123

Query: 127 ALRAYVKDHYSNGFCTVYAKTIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTA 186
           AL+ YV DHY  G C +  KT+  ++ +IACIE H ++    WNG W+S+W F + P   
Sbjct: 124 ALKLYVNDHYPKGNCNMLRKTVKSKEYLIACIEDHNYETGECWNGLWKSKWIFQVNPFLT 183

Query: 187 QVVGVLKIQVHYYEDGNVQLVSHKDVQDSLTVSNEAQTAKEFIKIIENAENEYQTAISEN 246
           QV G + +Q H++   N+ +   KD+++SL + N+AQ A  F +++E  EN++Q A+ E 
Sbjct: 184 QVTGRIFVQAHFFRCVNLHIEISKDLKESLEIVNQAQLALSFARLVEEQENKFQAAVLEE 243

Query: 247 YQTMSDTTF-KALRRQLPVTRTKIDWNKILS 276
            Q +S+    K LRR LPVTRT IDW++ILS
Sbjct: 244 LQELSNEALRKILRRDLPVTRTLIDWHRILS 274


>gi|31377575 ENTH domain containing 1 [Homo sapiens]
          Length = 607

 Score = 29.3 bits (64), Expect = 4.1
 Identities = 21/87 (24%), Positives = 39/87 (44%), Gaps = 11/87 (12%)

Query: 10  DEEKV-RIAAKFITHAPPG---EFNEVFNDVRLLLNNDNLLREGAAHA-------FAQYN 58
           DE+K  ++   F +  P     E N+  N + +L NN +  ++  +H        F+  N
Sbjct: 461 DEDKTAKLHHSFASRGPVSSDVEENDSLNLLGILPNNSDSAKKNISHISSSHWGEFSTQN 520

Query: 59  MDQFTPVKIEGYEDQVLITEHGDLGNS 85
           +DQF P+   G++      +  +  NS
Sbjct: 521 VDQFIPLSCSGFQSTKDFPQEPEAKNS 547


>gi|24308237 phosphatidylinositol transfer protein,
           membrane-associated 2 [Homo sapiens]
          Length = 1349

 Score = 28.9 bits (63), Expect = 5.4
 Identities = 14/66 (21%), Positives = 30/66 (45%), Gaps = 1/66 (1%)

Query: 52  HAFAQYNMDQFTPVKIEGYEDQVLITEHGDLGNSRFLDPRNKISFKFDHLRKEASDPQPE 111
           H+ +++ M        E  +D+     H DL ++  + P++   +  + L  +   P+PE
Sbjct: 323 HSISEWRMQSIARDSDESSDDE-FFDAHEDLSDTEEMFPKDITKWSSNDLMDKIESPEPE 381

Query: 112 EADGGL 117
           +   GL
Sbjct: 382 DTQDGL 387


>gi|55749769 CWC22 spliceosome-associated protein homolog [Homo
           sapiens]
          Length = 908

 Score = 28.1 bits (61), Expect = 9.2
 Identities = 17/62 (27%), Positives = 28/62 (45%), Gaps = 6/62 (9%)

Query: 21  ITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYEDQVLITEHG 80
           +T   P   N +F  +R      N+L E       QY ++    V+ +G++D  +I E  
Sbjct: 304 LTQVSPRGINAIFERLR------NILHESEIDKRVQYMIEVMFAVRKDGFKDHPIILEGL 357

Query: 81  DL 82
           DL
Sbjct: 358 DL 359


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,771,763
Number of Sequences: 37866
Number of extensions: 446810
Number of successful extensions: 1060
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1054
Number of HSP's gapped (non-prelim): 6
length of query: 286
length of database: 18,247,518
effective HSP length: 101
effective length of query: 185
effective length of database: 14,423,052
effective search space: 2668264620
effective search space used: 2668264620
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.