Guide to the Human Genome
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Search of human proteins with 5016090

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5016090 nuclear receptor subfamily 0, group B, member 1
[Homo sapiens]
         (470 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5016090 nuclear receptor subfamily 0, group B, member 1 [Homo...   984   0.0  
gi|13259503 short heterodimer partner [Homo sapiens]                  147   2e-35
gi|20070199 nuclear receptor subfamily 2, group F, member 6 [Hom...    92   1e-18
gi|36950991 nuclear receptor subfamily 2, group C, member 2 [Hom...    84   2e-16
gi|7657395 photoreceptor-specific nuclear receptor isoform b [Ho...    82   1e-15
gi|223555953 nuclear receptor subfamily 2, group F, member 2 iso...    79   1e-14
gi|223555951 nuclear receptor subfamily 2, group F, member 2 iso...    79   1e-14
gi|223555949 nuclear receptor subfamily 2, group F, member 2 iso...    79   1e-14
gi|14149746 nuclear receptor subfamily 2, group F, member 2 isof...    79   1e-14
gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo...    77   4e-14
gi|31077209 hepatocyte nuclear factor 4 alpha isoform c [Homo sa...    69   1e-11
gi|31077207 hepatocyte nuclear factor 4 alpha isoform a [Homo sa...    69   1e-11
gi|31077205 hepatocyte nuclear factor 4 alpha isoform b [Homo sa...    69   1e-11
gi|71725336 hepatocyte nuclear factor 4 alpha isoform f [Homo sa...    69   1e-11
gi|71725341 hepatocyte nuclear factor 4 alpha isoform e [Homo sa...    69   1e-11
gi|71725339 hepatocyte nuclear factor 4 alpha isoform d [Homo sa...    69   1e-11
gi|189491739 nuclear receptor subfamily 2, group C, member 1 iso...    67   5e-11
gi|11415052 retinoid X receptor, beta [Homo sapiens]                   66   8e-11
gi|4506755 retinoid X receptor, alpha [Homo sapiens]                   65   1e-10
gi|115583654 hepatocyte nuclear factor 4, gamma [Homo sapiens]         65   1e-10
gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]         64   3e-10
gi|45545405 nuclear receptor subfamily 5, group A, member 2 isof...    60   3e-09
gi|4504343 nuclear receptor subfamily 5, group A, member 2 isofo...    60   3e-09
gi|7706515 photoreceptor-specific nuclear receptor isoform a [Ho...    59   1e-08
gi|4507537 nuclear receptor subfamily 2, group E, member 1 [Homo...    58   2e-08
gi|45545429 estrogen-related receptor gamma isoform 2 [Homo sapi...    54   3e-07
gi|45545427 estrogen-related receptor gamma isoform 2 [Homo sapi...    54   3e-07
gi|45545433 estrogen-related receptor gamma isoform 1 [Homo sapi...    54   3e-07
gi|197209821 estrogen-related receptor gamma isoform 2 [Homo sap...    54   3e-07
gi|238550159 estrogen-related receptor beta [Homo sapiens]             48   2e-05

>gi|5016090 nuclear receptor subfamily 0, group B, member 1 [Homo
           sapiens]
          Length = 470

 Score =  984 bits (2545), Expect = 0.0
 Identities = 470/470 (100%), Positives = 470/470 (100%)

Query: 1   MAGENHQWQGSILYNMLMSAKQTRAAPEAPETRLVDQCWGCSCGDEPGVGREGLLGGRNV 60
           MAGENHQWQGSILYNMLMSAKQTRAAPEAPETRLVDQCWGCSCGDEPGVGREGLLGGRNV
Sbjct: 1   MAGENHQWQGSILYNMLMSAKQTRAAPEAPETRLVDQCWGCSCGDEPGVGREGLLGGRNV 60

Query: 61  ALLYRCCFCGKDHPRQGSILYSMLTSAKQTYAAPKAPEATLGPCWGCSCGSDPGVGRAGL 120
           ALLYRCCFCGKDHPRQGSILYSMLTSAKQTYAAPKAPEATLGPCWGCSCGSDPGVGRAGL
Sbjct: 61  ALLYRCCFCGKDHPRQGSILYSMLTSAKQTYAAPKAPEATLGPCWGCSCGSDPGVGRAGL 120

Query: 121 PGGRPVALLYRCCFCGEDHPRQGSILYSLLTSSKQTHVAPAAPEARPGGAWWDRSYFAQR 180
           PGGRPVALLYRCCFCGEDHPRQGSILYSLLTSSKQTHVAPAAPEARPGGAWWDRSYFAQR
Sbjct: 121 PGGRPVALLYRCCFCGEDHPRQGSILYSLLTSSKQTHVAPAAPEARPGGAWWDRSYFAQR 180

Query: 181 PGGKEALPGGRATALLYRCCFCGEDHPQQGSTLYCVPTSTNQAQAAPEERPRAPWWDTSS 240
           PGGKEALPGGRATALLYRCCFCGEDHPQQGSTLYCVPTSTNQAQAAPEERPRAPWWDTSS
Sbjct: 181 PGGKEALPGGRATALLYRCCFCGEDHPQQGSTLYCVPTSTNQAQAAPEERPRAPWWDTSS 240

Query: 241 GALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELA 300
           GALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELA
Sbjct: 241 GALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELA 300

Query: 301 QDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQA 360
           QDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQA
Sbjct: 301 QDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQA 360

Query: 361 IKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQ 420
           IKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQ
Sbjct: 361 IKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQ 420

Query: 421 GPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKI 470
           GPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKI
Sbjct: 421 GPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKI 470


>gi|13259503 short heterodimer partner [Homo sapiens]
          Length = 257

 Score =  147 bits (371), Expect = 2e-35
 Identities = 88/223 (39%), Positives = 117/223 (52%), Gaps = 13/223 (5%)

Query: 244 RPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQDR 303
           RPV L +P   C  A   L KT+ F++ LP F  LP   Q  L++ CW  L +L LAQD 
Sbjct: 45  RPVQLCAPHRTCREALDVLAKTVAFLRNLPSFWQLPPQDQRRLLQGCWGPLFLLGLAQDA 104

Query: 304 LQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQAIKC 363
           + FE  E   PS+L+KIL      +GG+  LP              R  PS + VQ ++C
Sbjct: 105 VTFEVAEAPVPSILKKILLEEPSSSGGSGQLP-------------DRPQPSLAAVQWLQC 151

Query: 364 FLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPH 423
            L   WSL +S KEYA LKGT+LFNPDVPGLQ   +I  LQ     +L E          
Sbjct: 152 CLESFWSLELSPKEYACLKGTILFNPDVPGLQAASHIGHLQQEAHWVLCEVLEPWCPAAQ 211

Query: 424 DRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEML 466
            R   +  T   L+ I  +++ +LFFRPIIG V +  ++ +ML
Sbjct: 212 GRLTRVLLTASTLKSIPTSLLGDLFFRPIIGDVDIAGLLGDML 254


>gi|20070199 nuclear receptor subfamily 2, group F, member 6 [Homo
           sapiens]
          Length = 404

 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 62/213 (29%), Positives = 97/213 (45%), Gaps = 24/213 (11%)

Query: 254 VCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQDRLQFETVEVSE 313
           VCE A+  L  T+ + ++ P F  LP+  Q+ L+R  W+ L +L  AQ  L   T  +  
Sbjct: 202 VCELAARLLFSTVEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLA 261

Query: 314 PSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQAIKCFLSKCWSLNI 373
            + L                        H AP A  R V    QV+A +  + K   L +
Sbjct: 262 AAGL------------------------HAAPMAAERAVAFMDQVRAFQEQVDKLGRLQV 297

Query: 374 STKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFIELNSTL 433
            + EY  LK   LF PD  GL    +++ LQ   Q  L+E+ R  +     RF  L   L
Sbjct: 298 DSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGRLLLRL 357

Query: 434 FLLRFINANVIAELFFRPIIGTVSMDDMMLEML 466
             LR + A++I++LFF  ++G   ++ ++ +ML
Sbjct: 358 PALRAVPASLISQLFFMRLVGKTPIETLIRDML 390


>gi|36950991 nuclear receptor subfamily 2, group C, member 2 [Homo
           sapiens]
          Length = 615

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 59/209 (28%), Positives = 95/209 (45%), Gaps = 18/209 (8%)

Query: 254 VCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQDRLQFETVEVSE 313
           +CE+AS  L  ++ + + +P FQ L  D    LVR CW  L  L LAQ        +V  
Sbjct: 405 ICESASRLLFLSMHWARSIPAFQALGQDCNTSLVRACWNELFTLGLAQ------CAQVMS 458

Query: 314 PSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQAIKCFLSKCWSLNI 373
            S +   +    + +   + L    ++  +              +  ++ F +    L+I
Sbjct: 459 LSTILAAIVNHLQNSIQEDKLSGDRIKQVM------------EHIWKLQEFCNSMAKLDI 506

Query: 374 STKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFIELNSTL 433
              EYAYLK  VLF+PD PGL     I+  Q   Q  L ++ + T+     R   +   L
Sbjct: 507 DGYEYAYLKAIVLFSPDHPGLTSTSQIEKFQEKAQMELQDYVQKTYSEDTYRLARILVRL 566

Query: 434 FLLRFINANVIAELFFRPIIGTVSMDDMM 462
             LR +++N+  ELFF  +IG VS+D ++
Sbjct: 567 PALRLMSSNITEELFFTGLIGNVSIDSII 595


>gi|7657395 photoreceptor-specific nuclear receptor isoform b [Homo
           sapiens]
          Length = 410

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 62/237 (26%), Positives = 109/237 (45%), Gaps = 32/237 (13%)

Query: 229 ERPRAPWWDTSSGALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVR 288
           E P +P+  +S     P  L S   + E ++  L   +++ K LP F  LP   Q++L+ 
Sbjct: 203 EFPSSPYSSSS-----PCGLDS---IHETSARLLFMAVKWAKNLPVFSSLPFRDQVILLE 254

Query: 289 NCWASLLMLELAQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAE 348
             W+ L +L   Q  L  ++  +  P                         +   A  A+
Sbjct: 255 EAWSELFLLGAIQWSLPLDSCPLLAPP------------------------EASAAGGAQ 290

Query: 349 ARKVPSASQVQAIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQ 408
            R   ++ + + ++  +S+  +L +   E+A +K  VLF P+  GL+  ++++ LQ  +Q
Sbjct: 291 GRLTLASMETRVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQ 350

Query: 409 QILSEHTRMTHQGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEM 465
            +LS+H++  H     RF +L   L  LRFI A  I  LFFR  IG   M+ ++ +M
Sbjct: 351 VMLSQHSKAHHPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDM 407


>gi|223555953 nuclear receptor subfamily 2, group F, member 2
           isoform c [Homo sapiens]
          Length = 261

 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 55/227 (24%), Positives = 103/227 (45%), Gaps = 24/227 (10%)

Query: 240 SGALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLEL 299
           S  ++P  +   + +CE A+  L   + + + +P F  L +  Q+ L+R  W+ L +L  
Sbjct: 45  SQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNA 104

Query: 300 AQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQ 359
           AQ  +      +   + L                        H +P +  R V     ++
Sbjct: 105 AQCSMPLHVAPLLAAAGL------------------------HASPMSADRVVAFMDHIR 140

Query: 360 AIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTH 419
             +  + K  +L++ + EY+ LK  VLF  D  GL  V +++ LQ  +Q  L E+ R  +
Sbjct: 141 IFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQY 200

Query: 420 QGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEML 466
                RF +L   L  LR ++++VI +LFF  ++G   ++ ++ +ML
Sbjct: 201 PNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDML 247


>gi|223555951 nuclear receptor subfamily 2, group F, member 2
           isoform c [Homo sapiens]
          Length = 261

 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 55/227 (24%), Positives = 103/227 (45%), Gaps = 24/227 (10%)

Query: 240 SGALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLEL 299
           S  ++P  +   + +CE A+  L   + + + +P F  L +  Q+ L+R  W+ L +L  
Sbjct: 45  SQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNA 104

Query: 300 AQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQ 359
           AQ  +      +   + L                        H +P +  R V     ++
Sbjct: 105 AQCSMPLHVAPLLAAAGL------------------------HASPMSADRVVAFMDHIR 140

Query: 360 AIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTH 419
             +  + K  +L++ + EY+ LK  VLF  D  GL  V +++ LQ  +Q  L E+ R  +
Sbjct: 141 IFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQY 200

Query: 420 QGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEML 466
                RF +L   L  LR ++++VI +LFF  ++G   ++ ++ +ML
Sbjct: 201 PNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDML 247


>gi|223555949 nuclear receptor subfamily 2, group F, member 2
           isoform b [Homo sapiens]
          Length = 281

 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 55/227 (24%), Positives = 103/227 (45%), Gaps = 24/227 (10%)

Query: 240 SGALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLEL 299
           S  ++P  +   + +CE A+  L   + + + +P F  L +  Q+ L+R  W+ L +L  
Sbjct: 65  SQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNA 124

Query: 300 AQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQ 359
           AQ  +      +   + L                        H +P +  R V     ++
Sbjct: 125 AQCSMPLHVAPLLAAAGL------------------------HASPMSADRVVAFMDHIR 160

Query: 360 AIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTH 419
             +  + K  +L++ + EY+ LK  VLF  D  GL  V +++ LQ  +Q  L E+ R  +
Sbjct: 161 IFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQY 220

Query: 420 QGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEML 466
                RF +L   L  LR ++++VI +LFF  ++G   ++ ++ +ML
Sbjct: 221 PNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDML 267


>gi|14149746 nuclear receptor subfamily 2, group F, member 2 isoform
           a [Homo sapiens]
          Length = 414

 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 55/227 (24%), Positives = 103/227 (45%), Gaps = 24/227 (10%)

Query: 240 SGALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLEL 299
           S  ++P  +   + +CE A+  L   + + + +P F  L +  Q+ L+R  W+ L +L  
Sbjct: 198 SQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNA 257

Query: 300 AQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQ 359
           AQ  +      +   + L                        H +P +  R V     ++
Sbjct: 258 AQCSMPLHVAPLLAAAGL------------------------HASPMSADRVVAFMDHIR 293

Query: 360 AIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTH 419
             +  + K  +L++ + EY+ LK  VLF  D  GL  V +++ LQ  +Q  L E+ R  +
Sbjct: 294 IFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQY 353

Query: 420 QGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEML 466
                RF +L   L  LR ++++VI +LFF  ++G   ++ ++ +ML
Sbjct: 354 PNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDML 400


>gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo
           sapiens]
          Length = 423

 Score = 76.6 bits (187), Expect = 4e-14
 Identities = 55/227 (24%), Positives = 102/227 (44%), Gaps = 24/227 (10%)

Query: 240 SGALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLEL 299
           S  ++P  +   + +CE A+  L   + + + +P F  L +  Q+ L+R  W+ L +L  
Sbjct: 205 SQCMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNA 264

Query: 300 AQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQ 359
           AQ  +      +   + L                        H +P +  R V     ++
Sbjct: 265 AQCSMPLHVAPLLAAAGL------------------------HASPMSADRVVAFMDHIR 300

Query: 360 AIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTH 419
             +  + K  +L++ + EY+ LK  VLF  D  GL    +I+ LQ  +Q  L E+ R  +
Sbjct: 301 IFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQY 360

Query: 420 QGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEML 466
                RF +L   L  LR ++++VI +LFF  ++G   ++ ++ +ML
Sbjct: 361 PNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDML 407


>gi|31077209 hepatocyte nuclear factor 4 alpha isoform c [Homo
           sapiens]
          Length = 417

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 60/227 (26%), Positives = 97/227 (42%), Gaps = 25/227 (11%)

Query: 240 SGALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLEL 299
           +G +R   + S   VCE+    LL  + + KY+P F  LPLD Q+ L+R      L+L  
Sbjct: 173 NGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGA 232

Query: 300 AQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQ 359
            +  + F+ V +                  GN+ +    +  H    AE  +V     ++
Sbjct: 233 TKRSMVFKDVLLL-----------------GNDYI----VPRHCPELAEMSRV----SIR 267

Query: 360 AIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTH 419
            +   +     L I   EYAYLK  + F+PD  GL     I+ L+   Q  L ++     
Sbjct: 268 ILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQ 327

Query: 420 QGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEML 466
                RF EL   L  L+ I   +I ++ F  + G   +D+++ EML
Sbjct: 328 YDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEML 374


>gi|31077207 hepatocyte nuclear factor 4 alpha isoform a [Homo
           sapiens]
          Length = 464

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 60/227 (26%), Positives = 97/227 (42%), Gaps = 25/227 (11%)

Query: 240 SGALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLEL 299
           +G +R   + S   VCE+    LL  + + KY+P F  LPLD Q+ L+R      L+L  
Sbjct: 173 NGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGA 232

Query: 300 AQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQ 359
            +  + F+ V +                  GN+ +    +  H    AE  +V     ++
Sbjct: 233 TKRSMVFKDVLLL-----------------GNDYI----VPRHCPELAEMSRV----SIR 267

Query: 360 AIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTH 419
            +   +     L I   EYAYLK  + F+PD  GL     I+ L+   Q  L ++     
Sbjct: 268 ILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQ 327

Query: 420 QGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEML 466
                RF EL   L  L+ I   +I ++ F  + G   +D+++ EML
Sbjct: 328 YDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEML 374


>gi|31077205 hepatocyte nuclear factor 4 alpha isoform b [Homo
           sapiens]
          Length = 474

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 60/227 (26%), Positives = 97/227 (42%), Gaps = 25/227 (11%)

Query: 240 SGALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLEL 299
           +G +R   + S   VCE+    LL  + + KY+P F  LPLD Q+ L+R      L+L  
Sbjct: 173 NGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGA 232

Query: 300 AQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQ 359
            +  + F+ V +                  GN+ +    +  H    AE  +V     ++
Sbjct: 233 TKRSMVFKDVLLL-----------------GNDYI----VPRHCPELAEMSRV----SIR 267

Query: 360 AIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTH 419
            +   +     L I   EYAYLK  + F+PD  GL     I+ L+   Q  L ++     
Sbjct: 268 ILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQ 327

Query: 420 QGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEML 466
                RF EL   L  L+ I   +I ++ F  + G   +D+++ EML
Sbjct: 328 YDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEML 374


>gi|71725336 hepatocyte nuclear factor 4 alpha isoform f [Homo
           sapiens]
          Length = 395

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 60/227 (26%), Positives = 97/227 (42%), Gaps = 25/227 (11%)

Query: 240 SGALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLEL 299
           +G +R   + S   VCE+    LL  + + KY+P F  LPLD Q+ L+R      L+L  
Sbjct: 151 NGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGA 210

Query: 300 AQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQ 359
            +  + F+ V +                  GN+ +    +  H    AE  +V     ++
Sbjct: 211 TKRSMVFKDVLLL-----------------GNDYI----VPRHCPELAEMSRV----SIR 245

Query: 360 AIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTH 419
            +   +     L I   EYAYLK  + F+PD  GL     I+ L+   Q  L ++     
Sbjct: 246 ILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQ 305

Query: 420 QGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEML 466
                RF EL   L  L+ I   +I ++ F  + G   +D+++ EML
Sbjct: 306 YDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEML 352


>gi|71725341 hepatocyte nuclear factor 4 alpha isoform e [Homo
           sapiens]
          Length = 442

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 60/227 (26%), Positives = 97/227 (42%), Gaps = 25/227 (11%)

Query: 240 SGALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLEL 299
           +G +R   + S   VCE+    LL  + + KY+P F  LPLD Q+ L+R      L+L  
Sbjct: 151 NGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGA 210

Query: 300 AQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQ 359
            +  + F+ V +                  GN+ +    +  H    AE  +V     ++
Sbjct: 211 TKRSMVFKDVLLL-----------------GNDYI----VPRHCPELAEMSRV----SIR 245

Query: 360 AIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTH 419
            +   +     L I   EYAYLK  + F+PD  GL     I+ L+   Q  L ++     
Sbjct: 246 ILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQ 305

Query: 420 QGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEML 466
                RF EL   L  L+ I   +I ++ F  + G   +D+++ EML
Sbjct: 306 YDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEML 352


>gi|71725339 hepatocyte nuclear factor 4 alpha isoform d [Homo
           sapiens]
          Length = 452

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 60/227 (26%), Positives = 97/227 (42%), Gaps = 25/227 (11%)

Query: 240 SGALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLEL 299
           +G +R   + S   VCE+    LL  + + KY+P F  LPLD Q+ L+R      L+L  
Sbjct: 151 NGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGA 210

Query: 300 AQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQ 359
            +  + F+ V +                  GN+ +    +  H    AE  +V     ++
Sbjct: 211 TKRSMVFKDVLLL-----------------GNDYI----VPRHCPELAEMSRV----SIR 245

Query: 360 AIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTH 419
            +   +     L I   EYAYLK  + F+PD  GL     I+ L+   Q  L ++     
Sbjct: 246 ILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQ 305

Query: 420 QGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEML 466
                RF EL   L  L+ I   +I ++ F  + G   +D+++ EML
Sbjct: 306 YDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEML 352


>gi|189491739 nuclear receptor subfamily 2, group C, member 1
           isoform a [Homo sapiens]
          Length = 603

 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 59/218 (27%), Positives = 91/218 (41%), Gaps = 32/218 (14%)

Query: 256 EAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQ-------DRLQFET 308
           E+AS  L  ++ +   +P FQ L  +  + LV+  W  L  L LAQ         +    
Sbjct: 395 ESASRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNVATILATF 454

Query: 309 VEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQAIKCFLSKC 368
           V     S+ Q  ++T RR+           L  H+    E               F +  
Sbjct: 455 VNCLHNSLQQDKMSTERRKL----------LMEHIFKLQE---------------FCNSM 489

Query: 369 WSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFIE 428
             L I   EYAYLK  VLF+PD P L+ ++ I+  Q        ++   T+     R   
Sbjct: 490 VKLCIDGYEYAYLKAIVLFSPDHPSLENMEQIEKFQEKAYVEFQDYITKTYPDDTYRLSR 549

Query: 429 LNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEML 466
           L   L  LR +NA +  ELFF+ +IG + +D ++  +L
Sbjct: 550 LLLRLPALRLMNATITEELFFKGLIGNIRIDSVIPHIL 587


>gi|11415052 retinoid X receptor, beta [Homo sapiens]
          Length = 533

 Score = 65.9 bits (159), Expect = 8e-11
 Identities = 53/213 (24%), Positives = 87/213 (40%), Gaps = 25/213 (11%)

Query: 254 VCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQDRLQFETVEVSE 313
           +C+AA   L   + + K +P F  LPLD Q++L+R  W  LL+   +       +++V +
Sbjct: 339 ICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSH-----RSIDVRD 393

Query: 314 PSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQAIKCFLSKCWSLNI 373
             +L   L   R               H     A   +V +          +SK   + +
Sbjct: 394 GILLATGLHVHRNSA------------HSAGVGAIFDRVLTE--------LVSKMRDMRM 433

Query: 374 STKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFIELNSTL 433
              E   L+  +LFNPD  GL     ++ L+      L  + +  +     RF +L   L
Sbjct: 434 DKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYPEQQGRFAKLLLRL 493

Query: 434 FLLRFINANVIAELFFRPIIGTVSMDDMMLEML 466
             LR I    +  LFF  +IG   +D  ++EML
Sbjct: 494 PALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 526


>gi|4506755 retinoid X receptor, alpha [Homo sapiens]
          Length = 462

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 61/246 (24%), Positives = 100/246 (40%), Gaps = 28/246 (11%)

Query: 222 QAQAAPEERPRAPWWDTSSGALRPVALKSPQV-VCEAASAGLLKTLRFVKYLPCFQVLPL 280
           +A+ A E  P+   +  ++  L P +   P   +C+AA   L   + + K +P F  LPL
Sbjct: 237 EAELAVE--PKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPL 294

Query: 281 DQQLVLVRNCWASLLMLELAQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQ 340
           D Q++L+R  W  LL+   +       ++ V +  +L   L   R               
Sbjct: 295 DDQVILLRAGWNELLIASFSH-----RSIAVKDGILLATGLHVHRNSA------------ 337

Query: 341 HHLAPPAEARKVPSASQVQAIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYI 400
           H     A   +V +          +SK   + +   E   L+  VLFNPD  GL     +
Sbjct: 338 HSAGVGAIFDRVLTE--------LVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEV 389

Query: 401 QGLQWGTQQILSEHTRMTHQGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDD 460
           + L+      L  + +  +     RF +L   L  LR I    +  LFF  +IG   +D 
Sbjct: 390 EALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDT 449

Query: 461 MMLEML 466
            ++EML
Sbjct: 450 FLMEML 455


>gi|115583654 hepatocyte nuclear factor 4, gamma [Homo sapiens]
          Length = 445

 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 62/251 (24%), Positives = 104/251 (41%), Gaps = 26/251 (10%)

Query: 216 VPTSTNQAQAAPEERPRAPWWDTSSGALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCF 275
           +P+    AQA    R  +     SS  +    + S   VCE+    LL  + + KY+P F
Sbjct: 138 IPSINTLAQAEVRSRQISVSSPGSSTDINVKKIASIGDVCESMKQQLLVLVEWAKYIPAF 197

Query: 276 QVLPLDQQLVLVRNCWASLLMLELAQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLP 335
             LPLD Q+ L+R      L+L   +  + ++ + +                 G N  + 
Sbjct: 198 CELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILL----------------LGNNYVI- 240

Query: 336 VPTLQHHLAPPAEARKVPSASQVQAIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQ 395
                H  +   E  +V +    + ++ F      + I   EYA LK  V F+PD  GL 
Sbjct: 241 -----HRNSCEVEISRVANRVLDELVRPFQE----IQIDDNEYACLKAIVFFDPDAKGLS 291

Query: 396 CVKYIQGLQWGTQQILSEHTRMTHQGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGT 455
               I+ +++  Q  L ++          RF EL   L  L+ I   +I ++ F  + G 
Sbjct: 292 DPVKIKNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGM 351

Query: 456 VSMDDMMLEML 466
           V +D+++ EML
Sbjct: 352 VKIDNLLQEML 362


>gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]
          Length = 463

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 55/217 (25%), Positives = 88/217 (40%), Gaps = 25/217 (11%)

Query: 254 VCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQDRLQFETVEVSE 313
           +C AA   L   + + K +P F  L L+ Q++L+R  W  LL+   +       +V V +
Sbjct: 269 ICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSH-----RSVSVQD 323

Query: 314 PSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQAIKCFLSKCWSLNI 373
             +L   L   R                     A +  V S    + +   +SK   + +
Sbjct: 324 GILLATGLHVHRSS-------------------AHSAGVGSIFD-RVLTELVSKMKDMQM 363

Query: 374 STKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFIELNSTL 433
              E   L+  VLFNPD  GL     ++ L+      L  +T+  +     RF +L   L
Sbjct: 364 DKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRL 423

Query: 434 FLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKI 470
             LR I    +  LFF  +IG   +D  ++EML T +
Sbjct: 424 PALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETPL 460


>gi|45545405 nuclear receptor subfamily 5, group A, member 2 isoform
           1 [Homo sapiens]
          Length = 541

 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 53/217 (24%), Positives = 99/217 (45%), Gaps = 21/217 (9%)

Query: 253 VVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQDRLQFETVEVS 312
           ++C+ A   L   + + +    F+ L +D Q+ L++NCW+ LL+L    D +  + V   
Sbjct: 344 LMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLIL----DHIYRQVVHGK 399

Query: 313 EPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQAIKCFLSKCWSLN 372
           E S+           TG      +      +A  A A      S  Q +   ++K  SL 
Sbjct: 400 EGSIFLV--------TGQQVDYSI------IASQAGATLNNLMSHAQEL---VAKLRSLQ 442

Query: 373 ISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFIELNST 432
              +E+  LK  VLF+ DV  L+  + ++G+Q      L ++T   +    ++F +L   
Sbjct: 443 FDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLR 502

Query: 433 LFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTK 469
           L  +R I+      L+++ + G V  +++++EML  K
Sbjct: 503 LPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAK 539


>gi|4504343 nuclear receptor subfamily 5, group A, member 2 isoform
           2 [Homo sapiens]
          Length = 495

 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 53/217 (24%), Positives = 99/217 (45%), Gaps = 21/217 (9%)

Query: 253 VVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQDRLQFETVEVS 312
           ++C+ A   L   + + +    F+ L +D Q+ L++NCW+ LL+L    D +  + V   
Sbjct: 298 LMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLIL----DHIYRQVVHGK 353

Query: 313 EPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQAIKCFLSKCWSLN 372
           E S+           TG      +      +A  A A      S  Q +   ++K  SL 
Sbjct: 354 EGSIFLV--------TGQQVDYSI------IASQAGATLNNLMSHAQEL---VAKLRSLQ 396

Query: 373 ISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFIELNST 432
              +E+  LK  VLF+ DV  L+  + ++G+Q      L ++T   +    ++F +L   
Sbjct: 397 FDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLR 456

Query: 433 LFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTK 469
           L  +R I+      L+++ + G V  +++++EML  K
Sbjct: 457 LPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAK 493


>gi|7706515 photoreceptor-specific nuclear receptor isoform a [Homo
           sapiens]
          Length = 367

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 44/191 (23%), Positives = 86/191 (45%), Gaps = 32/191 (16%)

Query: 229 ERPRAPWWDTSSGALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVR 288
           E P +P+  +S     P  L S   + E ++  L   +++ K LP F  LP   Q++L+ 
Sbjct: 203 EFPSSPYSSSS-----PCGLDS---IHETSARLLFMAVKWAKNLPVFSSLPFRDQVILLE 254

Query: 289 NCWASLLMLELAQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAE 348
             W+ L +L   Q  L  ++  +  P                         +   A  A+
Sbjct: 255 EAWSELFLLGAIQWSLPLDSCPLLAPP------------------------EASAAGGAQ 290

Query: 349 ARKVPSASQVQAIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQ 408
            R   ++ + + ++  +S+  +L +   E+A +K  VLF P+  GL+  ++++ LQ  +Q
Sbjct: 291 GRLTLASMETRVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQ 350

Query: 409 QILSEHTRMTH 419
            +LS+H++  H
Sbjct: 351 VMLSQHSKAHH 361


>gi|4507537 nuclear receptor subfamily 2, group E, member 1 [Homo
           sapiens]
          Length = 385

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 54/219 (24%), Positives = 94/219 (42%), Gaps = 31/219 (14%)

Query: 254 VCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQDRLQFETVEVSE 313
           VCE+A+  L  ++++ K +P F  L L  QL+L+ + W  L +L +AQ  +  +      
Sbjct: 185 VCESAARLLFMSIKWAKSVPAFSTLSLQDQLMLLEDAWRELFVLGIAQWAIPVD------ 238

Query: 314 PSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQAIKCFLSKCWSLNI 373
                            N  L V  +        +  K+   S++QA++  +++   L +
Sbjct: 239 ----------------ANTLLAVSGMNGDNTDSQKLNKI--ISEIQALQEVVARFRQLRL 280

Query: 374 STKEYAYLKGTVLFN--PDVPGLQCVKY-----IQGLQWGTQQILSEHTRMTHQGPHDRF 426
              E+A LK  V F   P   G +   +     I  LQ   Q  L+ +    +     RF
Sbjct: 281 DATEFACLKCIVTFKAVPTHSGSELRSFRNAAAIAALQDEAQLTLNSYIHTRYPTQPCRF 340

Query: 427 IELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEM 465
            +L   L  LR I+ + I E+FF+  IG V +  ++ +M
Sbjct: 341 GKLLLLLPALRSISPSTIEEVFFKKTIGNVPITRLLSDM 379


>gi|45545429 estrogen-related receptor gamma isoform 2 [Homo
           sapiens]
          Length = 435

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 51/223 (22%), Positives = 90/223 (40%), Gaps = 26/223 (11%)

Query: 248 LKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQDRLQFE 307
           +K+   +C+ A   L+  + + K++P F  L L  Q+ L+++ W  +L+L +    L FE
Sbjct: 239 IKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFE 298

Query: 308 TVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQAIKCFLSK 367
              V        I+   + +  G   L    LQ                        + K
Sbjct: 299 DELVYADDY---IMDEDQSKLAGLLDLNNAILQ-----------------------LVKK 332

Query: 368 CWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFI 427
             S+ +  +E+  LK   L N D   ++ V+ +Q LQ    + L ++    H     R  
Sbjct: 333 YKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAG 392

Query: 428 ELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKI 470
           ++  TL LLR  +   +   +   + G V M  + LEML  K+
Sbjct: 393 KMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEAKV 435


>gi|45545427 estrogen-related receptor gamma isoform 2 [Homo
           sapiens]
          Length = 435

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 51/223 (22%), Positives = 90/223 (40%), Gaps = 26/223 (11%)

Query: 248 LKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQDRLQFE 307
           +K+   +C+ A   L+  + + K++P F  L L  Q+ L+++ W  +L+L +    L FE
Sbjct: 239 IKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFE 298

Query: 308 TVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQAIKCFLSK 367
              V        I+   + +  G   L    LQ                        + K
Sbjct: 299 DELVYADDY---IMDEDQSKLAGLLDLNNAILQ-----------------------LVKK 332

Query: 368 CWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFI 427
             S+ +  +E+  LK   L N D   ++ V+ +Q LQ    + L ++    H     R  
Sbjct: 333 YKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAG 392

Query: 428 ELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKI 470
           ++  TL LLR  +   +   +   + G V M  + LEML  K+
Sbjct: 393 KMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEAKV 435


>gi|45545433 estrogen-related receptor gamma isoform 1 [Homo
           sapiens]
          Length = 458

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 51/223 (22%), Positives = 90/223 (40%), Gaps = 26/223 (11%)

Query: 248 LKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQDRLQFE 307
           +K+   +C+ A   L+  + + K++P F  L L  Q+ L+++ W  +L+L +    L FE
Sbjct: 262 IKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFE 321

Query: 308 TVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQAIKCFLSK 367
              V        I+   + +  G   L    LQ                        + K
Sbjct: 322 DELVYADDY---IMDEDQSKLAGLLDLNNAILQ-----------------------LVKK 355

Query: 368 CWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFI 427
             S+ +  +E+  LK   L N D   ++ V+ +Q LQ    + L ++    H     R  
Sbjct: 356 YKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAG 415

Query: 428 ELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKI 470
           ++  TL LLR  +   +   +   + G V M  + LEML  K+
Sbjct: 416 KMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEAKV 458


>gi|197209821 estrogen-related receptor gamma isoform 2 [Homo
           sapiens]
          Length = 435

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 51/223 (22%), Positives = 90/223 (40%), Gaps = 26/223 (11%)

Query: 248 LKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQDRLQFE 307
           +K+   +C+ A   L+  + + K++P F  L L  Q+ L+++ W  +L+L +    L FE
Sbjct: 239 IKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFE 298

Query: 308 TVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQAIKCFLSK 367
              V        I+   + +  G   L    LQ                        + K
Sbjct: 299 DELVYADDY---IMDEDQSKLAGLLDLNNAILQ-----------------------LVKK 332

Query: 368 CWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFI 427
             S+ +  +E+  LK   L N D   ++ V+ +Q LQ    + L ++    H     R  
Sbjct: 333 YKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAG 392

Query: 428 ELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKI 470
           ++  TL LLR  +   +   +   + G V M  + LEML  K+
Sbjct: 393 KMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEAKV 435


>gi|238550159 estrogen-related receptor beta [Homo sapiens]
          Length = 508

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 46/223 (20%), Positives = 88/223 (39%), Gaps = 26/223 (11%)

Query: 248 LKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQDRLQFE 307
           +K+   +C+ A   L+  + + K++P F  L L  Q+ L+++ W  +L+L +    L ++
Sbjct: 237 IKALTTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYD 296

Query: 308 TVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQAIKCFLSK 367
              V                            + ++     +R        +AI   + +
Sbjct: 297 DKLV--------------------------YAEDYIMDEEHSRLAGLLELYRAILQLVRR 330

Query: 368 CWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFI 427
              L +  +E+  LK   L N D   ++ ++ +Q LQ    + L ++          R  
Sbjct: 331 YKKLKVEKEEFVTLKALALANSDSMYIEDLEAVQKLQDLLHEALQDYELSQRHEEPWRTG 390

Query: 428 ELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKI 470
           +L  TL LLR   A  +   +   + G V M  + LEML  K+
Sbjct: 391 KLLLTLPLLRQTAAKAVQHFYSVKLQGKVPMHKLFLEMLEAKV 433


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.442 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,384,584
Number of Sequences: 37866
Number of extensions: 1048194
Number of successful extensions: 3310
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 3172
Number of HSP's gapped (non-prelim): 133
length of query: 470
length of database: 18,247,518
effective HSP length: 106
effective length of query: 364
effective length of database: 14,233,722
effective search space: 5181074808
effective search space used: 5181074808
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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