Search of human proteins with 48762920

Search of human proteins with 48762920

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|48762920 liver phosphofructokinase [Homo sapiens]
         (780 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|48762920 liver phosphofructokinase [Homo sapiens]                 1558   0.0  
gi|4505749 phosphofructokinase, muscle [Homo sapiens]                1129   0.0  
gi|11321601 phosphofructokinase, platelet [Homo sapiens]             1098   0.0  
gi|89363047 death-associated protein kinase 1 [Homo sapiens]           30   6.6  
gi|28373126 contactin 4 isoform c precursor [Homo sapiens]             30   6.6  
gi|28373124 contactin 4 isoform b precursor [Homo sapiens]             30   6.6  
gi|28373122 contactin 4 isoform a precursor [Homo sapiens]             30   6.6  

>gi|48762920 liver phosphofructokinase [Homo sapiens]
          Length = 780

 Score = 1558 bits (4034), Expect = 0.0
 Identities = 780/780 (100%), Positives = 780/780 (100%)

Query: 1   MAAVDLEKLRASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVE 60
           MAAVDLEKLRASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVE
Sbjct: 1   MAAVDLEKLRASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVE 60

Query: 61  GGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDG 120
           GGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDG
Sbjct: 61  GGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDG 120

Query: 121 SLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDS 180
           SLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDS
Sbjct: 121 SLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDS 180

Query: 181 ALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWE 240
           ALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWE
Sbjct: 181 ALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWE 240

Query: 241 NFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQ 300
           NFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQ
Sbjct: 241 NFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQ 300

Query: 301 RGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQK 360
           RGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQK
Sbjct: 301 RGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQK 360

Query: 361 AMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRS 420
           AMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRS
Sbjct: 361 AMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRS 420

Query: 421 AVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESI 480
           AVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESI
Sbjct: 421 AVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESI 480

Query: 481 VENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLG 540
           VENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLG
Sbjct: 481 VENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLG 540

Query: 541 SDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFN 600
           SDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFN
Sbjct: 541 SDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFN 600

Query: 601 IHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGH 660
           IHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGH
Sbjct: 601 IHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGH 660

Query: 661 LQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFS 720
           LQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFS
Sbjct: 661 LQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFS 720

Query: 721 PVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQYRISMAAYVSGELEHVTRRTLSMDKGF 780
           PVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQYRISMAAYVSGELEHVTRRTLSMDKGF
Sbjct: 721 PVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQYRISMAAYVSGELEHVTRRTLSMDKGF 780


>gi|4505749 phosphofructokinase, muscle [Homo sapiens]
          Length = 780

 Score = 1129 bits (2920), Expect = 0.0
 Identities = 535/761 (70%), Positives = 644/761 (84%), Gaps = 1/761 (0%)

Query: 13  GAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLS 72
           G GKAI VLTSGGDAQGMNAAVRAV R+GI+ GA+VF ++EGY+GLV+GG++IK+A W S
Sbjct: 13  GIGKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIKEATWES 72

Query: 73  VSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEW 132
           VS ++QLGGT+IGSARCK F  REGR  AAYNLV+ GITNLCVIGGDGSLTGA+ FRSEW
Sbjct: 73  VSMMLQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEW 132

Query: 133 GSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAI 192
             LL +L   GKI++  A   S+LNI GLVGSIDNDFCGTDMTIGTDSALHRIME++DAI
Sbjct: 133 SDLLSDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIMEIVDAI 192

Query: 193 TTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRS 252
           TTTAQSHQRTFVLEVMGRHCGYLALV++L+ GADW+FIPE PP+D WE  +C RL ETR+
Sbjct: 193 TTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHLCRRLSETRT 252

Query: 253 RGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRIL 312
           RGSRLNIII+AEGAID+NGKPI+S  +K+LVV+RLG+DTRVTVLGHVQRGGTPSAFDRIL
Sbjct: 253 RGSRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRIL 312

Query: 313 SSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQ 372
            S+MG+EAVMALLE TPDTPACVV+LSGNQ+VRLPLMECVQ+TK+V KAMD+K+FDEA +
Sbjct: 313 GSRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALK 372

Query: 373 LRGGSFENNWNIYKLLAHQKPPKEKS-NFSLAILNVGAPAAGMNAAVRSAVRTGISHGHT 431
           LRG SF NNW +YKLLAH +PP  KS + ++A++NVGAPAAGMNAAVRS VR G+  G+ 
Sbjct: 373 LRGRSFMNNWEVYKLLAHVRPPVSKSGSHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNR 432

Query: 432 VYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHA 491
           V VVHDGFEGLAKGQ++E GW  V GW G+GGS LGTKRTLPK   E I  NI  + I  
Sbjct: 433 VLVVHDGFEGLAKGQIEEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQISANITKFNIQG 492

Query: 492 LLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMES 551
           L+++GGFEAY G L+L+E R +++ELCI   VIPAT+SNNVPG+DFS+G+DTA+N    +
Sbjct: 493 LVIIGGFEAYTGGLELMEGRKQFDELCIPFVVIPATVSNNVPGSDFSVGADTALNTICTT 552

Query: 552 CDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHM 611
           CDRIKQSA+GTKRRVFI+ETMGGYCGYLAT+ G+A GADAAY+FE+PF I DL+ NVEH+
Sbjct: 553 CDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPFTIRDLQANVEHL 612

Query: 612 TEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFD 671
            +KMKT ++RGLVLRNEKC++ YTT+F++NLYS EGKG+FD R NVLGH+QQGG+PTPFD
Sbjct: 613 VQKMKTTVKRGLVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPTPFD 672

Query: 672 RNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDF 731
           RN+ TK+G KAM W+S K++E YR GR+FAN PDS CV+G++K+A+ F PV ELK  TDF
Sbjct: 673 RNFATKMGAKAMNWMSGKIKESYRNGRIFANTPDSGCVLGMRKRALVFQPVAELKDQTDF 732

Query: 732 EHRMPREQWWLSLRLMLKMLAQYRISMAAYVSGELEHVTRR 772
           EHR+P+EQWWL LR +LK+LA+Y I +       LEH+TR+
Sbjct: 733 EHRIPKEQWWLKLRPILKILAKYEIDLDTSDHAHLEHITRK 773


>gi|11321601 phosphofructokinase, platelet [Homo sapiens]
          Length = 784

 Score = 1098 bits (2840), Expect = 0.0
 Identities = 524/760 (68%), Positives = 639/760 (84%), Gaps = 3/760 (0%)

Query: 12  SGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWL 71
           SGAGKAIGVLTSGGDAQGMNAAVRAV RMGIYVGAKV+ IYEGY+G+V+GG NI +A+W 
Sbjct: 21  SGAGKAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWE 80

Query: 72  SVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSE 131
           SVS+I+Q+GGTIIGSARC+AF TREGR  AA NL+Q GITNLCVIGGDGSLTGAN+FR E
Sbjct: 81  SVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKE 140

Query: 132 WGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDA 191
           W  LLEEL   G+I +   + Y++LN+ G+VGSIDNDFCGTDMTIGTDSALHRI+EV+DA
Sbjct: 141 WSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDA 200

Query: 192 ITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETR 251
           I TTAQSHQRTFVLEVMGRHCGYLALVSALA GADW+F+PE+PPE+GWE  MC +L E R
Sbjct: 201 IMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENR 260

Query: 252 SRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRI 311
           +R  RLNIII+AEGAID   KPI+S  +K+LVV +LG+DTRVT+LGHVQRGGTPSAFDRI
Sbjct: 261 ARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRI 320

Query: 312 LSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEAT 371
           L+S+MG+EAV+ALLEATPDTPACVV+L+GN +VRLPLMECVQMT++VQKAMD++RF +A 
Sbjct: 321 LASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAV 380

Query: 372 QLRGGSFENNWNIYKLLAHQKPPKE--KSNFSLAILNVGAPAAGMNAAVRSAVRTGISHG 429
           +LRG SF  N N YK LA + P  +  K+N ++A++NVGAPAAGMNAAVRSAVR GI+ G
Sbjct: 381 RLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADG 440

Query: 430 HTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGI 489
           H +  ++DGF+G AKGQ++E+GW DV GW G+GGS+LGTKR LP   LE I   +R + I
Sbjct: 441 HRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSI 500

Query: 490 HALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAM 549
           +ALL++GGFEAY G+L+L  AR ++EE C+ M ++PAT+SNNVPG+DFS+G+DTA+N   
Sbjct: 501 NALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTIT 560

Query: 550 ESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVE 609
           ++CDRIKQSASGTKRRVFI+ETMGGYCGYLA + G+A GADAAY+FE+PF+I DL+ NVE
Sbjct: 561 DTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVE 620

Query: 610 HMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTP 669
           H+TEKMKT IQRGLVLRNE C + YTT+F+Y LYS EGKGVFDCR NVLGH+QQGGAP+P
Sbjct: 621 HLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSP 680

Query: 670 FDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDT 729
           FDRN+GTK+  +AM W++ KL+E   +G+ F    DS CV+G+ K+ V F PV ELKK T
Sbjct: 681 FDRNFGTKISARAMEWITAKLKEARGRGKKF-TTDDSICVLGISKRNVIFQPVAELKKQT 739

Query: 730 DFEHRMPREQWWLSLRLMLKMLAQYRISMAAYVSGELEHV 769
           DFEHR+P+EQWWL LR ++K+LA+Y+ S     SG+LEHV
Sbjct: 740 DFEHRIPKEQWWLKLRPLMKILAKYKASYDVSDSGQLEHV 779


>gi|89363047 death-associated protein kinase 1 [Homo sapiens]
          Length = 1430

 Score = 30.4 bits (67), Expect = 6.6
 Identities = 13/36 (36%), Positives = 22/36 (61%)

Query: 133 GSLLEELVAEGKISETTARTYSHLNIAGLVGSIDND 168
           G+ +E L  +GK +E  AR+  H ++AGL+  +  D
Sbjct: 633 GASVEALTTDGKTAEDLARSEQHEHVAGLLARLRKD 668


>gi|28373126 contactin 4 isoform c precursor [Homo sapiens]
          Length = 698

 Score = 30.4 bits (67), Expect = 6.6
 Identities = 23/98 (23%), Positives = 36/98 (36%), Gaps = 19/98 (19%)

Query: 624 VLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAP---------------- 667
           V RNE  H +   E    +++++G+G F   T V    ++   P                
Sbjct: 433 VFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEV 492

Query: 668 ---TPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFAN 702
              +P ++N G   G +   W  E   E  RK R   N
Sbjct: 493 FWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGN 530


>gi|28373124 contactin 4 isoform b precursor [Homo sapiens]
          Length = 282

 Score = 30.4 bits (67), Expect = 6.6
 Identities = 23/98 (23%), Positives = 36/98 (36%), Gaps = 19/98 (19%)

Query: 624 VLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAP---------------- 667
           V RNE  H +   E    +++++G+G F   T V    ++   P                
Sbjct: 17  VFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEV 76

Query: 668 ---TPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFAN 702
              +P ++N G   G +   W  E   E  RK R   N
Sbjct: 77  FWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGN 114


>gi|28373122 contactin 4 isoform a precursor [Homo sapiens]
          Length = 1026

 Score = 30.4 bits (67), Expect = 6.6
 Identities = 23/98 (23%), Positives = 36/98 (36%), Gaps = 19/98 (19%)

Query: 624 VLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAP---------------- 667
           V RNE  H +   E    +++++G+G F   T V    ++   P                
Sbjct: 761 VFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEV 820

Query: 668 ---TPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFAN 702
              +P ++N G   G +   W  E   E  RK R   N
Sbjct: 821 FWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGN 858


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,227,507
Number of Sequences: 37866
Number of extensions: 1226515
Number of successful extensions: 2318
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 2281
Number of HSP's gapped (non-prelim): 8
length of query: 780
length of database: 18,247,518
effective HSP length: 110
effective length of query: 670
effective length of database: 14,082,258
effective search space: 9435112860
effective search space used: 9435112860
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.