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Search of human proteins with 46488946
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46488946 killer cell immunoglobulin-like receptor, three
domains, long cytoplasmic tail, 3 [Homo sapiens]
(410 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46488946 killer cell immunoglobulin-like receptor, three doma... 852 0.0
gi|134268642 killer cell immunoglobulin-like receptor, three dom... 651 0.0
gi|134268644 killer cell immunoglobulin-like receptor, three dom... 639 0.0
gi|134133244 killer cell immunoglobulin-like receptor, three dom... 527 e-150
gi|62632748 killer-cell Ig-like receptor [Homo sapiens] 524 e-149
gi|71143139 killer cell immunoglobulin-like receptor, two domain... 476 e-134
gi|134304833 killer cell immunoglobulin-like receptor, two domai... 461 e-130
gi|110611923 killer cell immunoglobulin-like receptor, two domai... 454 e-128
gi|6912472 killer cell immunoglobulin-like receptor, two domains... 417 e-117
gi|7657277 killer cell immunoglobulin-like receptor, two domains... 413 e-115
gi|116517309 killer cell immunoglobulin-like receptor, two domai... 410 e-115
gi|134304835 killer cell immunoglobulin-like receptor, two domai... 397 e-111
gi|6912474 killer cell immunoglobulin-like receptor, two domains... 382 e-106
gi|11968154 killer cell immunoglobulin-like receptor, two domain... 363 e-100
gi|124107606 killer cell immunoglobulin-like receptor, two domai... 353 2e-97
gi|66267727 killer cell immunoglobulin-like receptor, two domain... 353 2e-97
gi|124107610 killer cell immunoglobulin-like receptor, two domai... 301 5e-82
gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B... 260 2e-69
gi|124107604 killer cell immunoglobulin-like receptor, two domai... 258 5e-69
gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B... 258 9e-69
gi|110611910 leukocyte immunoglobulin-like receptor, subfamily A... 246 4e-65
gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B... 241 9e-64
gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B... 241 1e-63
gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B... 239 4e-63
gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B... 239 4e-63
gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B... 238 6e-63
gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B... 238 6e-63
gi|71143143 killer cell immunoglobulin-like receptor, two domain... 238 1e-62
gi|5803066 leukocyte immunoglobulin-like receptor, subfamily A (... 225 5e-59
gi|47519953 leukocyte immunoglobulin-like receptor subfamily A m... 219 5e-57
>gi|46488946 killer cell immunoglobulin-like receptor, three
domains, long cytoplasmic tail, 3 [Homo sapiens]
Length = 410
Score = 852 bits (2202), Expect = 0.0
Identities = 410/410 (100%), Positives = 410/410 (100%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60
MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL
Sbjct: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60
Query: 61 SKEDGMPVPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGV 120
SKEDGMPVPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGV
Sbjct: 61 SKEDGMPVPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGV 120
Query: 121 HRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNY 180
HRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNY
Sbjct: 121 HRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNY 180
Query: 181 SMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGENV 240
SMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGENV
Sbjct: 181 SMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGENV 240
Query: 241 TLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFRAL 300
TLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFRAL
Sbjct: 241 TLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFRAL 300
Query: 301 PHAWSDPSDPLPVSVTGNSRHLHVLIGTSVVIIPFAILLFFLLHRWCANKKNAVVMDQEP 360
PHAWSDPSDPLPVSVTGNSRHLHVLIGTSVVIIPFAILLFFLLHRWCANKKNAVVMDQEP
Sbjct: 301 PHAWSDPSDPLPVSVTGNSRHLHVLIGTSVVIIPFAILLFFLLHRWCANKKNAVVMDQEP 360
Query: 361 AGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDTSV 410
AGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDTSV
Sbjct: 361 AGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDTSV 410
>gi|134268642 killer cell immunoglobulin-like receptor, three
domains, long cytoplasmic tail, 2 precursor [Homo
sapiens]
Length = 455
Score = 651 bits (1679), Expect = 0.0
Identities = 322/427 (75%), Positives = 349/427 (81%), Gaps = 17/427 (3%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60
MSL VVSMACVGFFLL+G WP +GGQDKPFLSA P TVV G HV LQC R GFN F L
Sbjct: 1 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFML 60
Query: 61 SKEDGMPVPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGV 120
KED VP + RIF+ SF+MGPVTPAHAGTYRC S PHS TGWSAPSNP+VIMVTG
Sbjct: 61 YKEDRSHVPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGN 120
Query: 121 HRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNY 180
HRKPSLLAHPGPL+KSGETVILQCWSDV FE F LHREGI+EDP RLVGQ+HD S+ N+
Sbjct: 121 HRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANF 180
Query: 181 SMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGENV 240
S+GP+ P LAGTYRC+GSV H PY+LSAPSDPLDIV+ GLY KPSLSAQPGPTVQAGENV
Sbjct: 181 SIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGENV 240
Query: 241 TLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFRAL 300
TLSCSS S +DIYHLSRE EA E RL AV +VN TFQA+FPLGP THGG YRCFGSFRAL
Sbjct: 241 TLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPATHGGTYRCFGSFRAL 300
Query: 301 PHAWSDPSDPLPVSVTGN-----------------SRHLHVLIGTSVVIIPFAILLFFLL 343
P WS+ SDPL VSVTGN RHLHVLIGTSVVI F +LLFFLL
Sbjct: 301 PCVWSNSSDPLLVSVTGNPSSSWPSPTEPSSKSGICRHLHVLIGTSVVIFLFILLLFFLL 360
Query: 344 HRWCANKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKT 403
+RWC+NKKNA VMDQEPAG+RTVNR+DSDEQDPQEVTYAQL+HCVF QRKI+RPSQRPKT
Sbjct: 361 YRWCSNKKNAAVMDQEPAGDRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISRPSQRPKT 420
Query: 404 PPTDTSV 410
P TDTSV
Sbjct: 421 PLTDTSV 427
>gi|134268644 killer cell immunoglobulin-like receptor, three
domains, long cytoplasmic tail, 1 precursor [Homo
sapiens]
Length = 444
Score = 639 bits (1648), Expect = 0.0
Identities = 313/425 (73%), Positives = 342/425 (80%), Gaps = 17/425 (4%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60
MSLMVVSMACVG FL++ PH+GGQDKPFLSAWP VV G HVTL+C R FN F L
Sbjct: 1 MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
Query: 61 SKEDGMPVPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGV 120
KED + +P + RIF+ SF M PVT AHAG Y C SHPHSPTGWSAPSNPVVIMVTG
Sbjct: 61 YKEDRIHIPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGN 120
Query: 121 HRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNY 180
HRKPSLLAHPGPLVKSGE VILQCWSD+ FE F LH+EGI++DP RLVGQ+HD S+ N+
Sbjct: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANF 180
Query: 181 SMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGENV 240
S+GPM ALAGTYRC+GSVTH PY+LSAPSDPLDIVV G Y KPSLSAQPGP VQAGE+V
Sbjct: 181 SIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESV 240
Query: 241 TLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFRAL 300
TLSCSSRS +D+YHLSRE A E RL AV +VN TFQA+FPLGP THGG YRCFGSFR
Sbjct: 241 TLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHS 300
Query: 301 PHAWSDPSDPLPVSVT-----------------GNSRHLHVLIGTSVVIIPFAILLFFLL 343
P+ WSDPSDPL VSVT GN RHLH+LIGTSVVII F +LLFFLL
Sbjct: 301 PYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNPRHLHILIGTSVVIILFILLLFFLL 360
Query: 344 HRWCANKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKT 403
H WC+NKKNA VMDQEPAGNRT N EDSDEQDP+EVTYAQL+HCVFTQRKITRPSQRPKT
Sbjct: 361 HLWCSNKKNAAVMDQEPAGNRTANSEDSDEQDPEEVTYAQLDHCVFTQRKITRPSQRPKT 420
Query: 404 PPTDT 408
PPTDT
Sbjct: 421 PPTDT 425
>gi|134133244 killer cell immunoglobulin-like receptor, three
domains, short cytoplasmic tail, 1 [Homo sapiens]
Length = 382
Score = 527 bits (1358), Expect = e-150
Identities = 260/368 (70%), Positives = 286/368 (77%), Gaps = 17/368 (4%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60
M LMVVSMACVG FL++ PH+GGQDKPFLSAWP VV G HVTL+C R FN F L
Sbjct: 1 MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60
Query: 61 SKEDGMPVPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGV 120
KED + VP + RIF+ F M PVT AHAG Y C SHPHSPTGWSAPSNP+VIMVTG
Sbjct: 61 YKEDRIHVPIFHGRIFQEGFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGN 120
Query: 121 HRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNY 180
HRKPSLLAHPGPLVKSGE VILQCWSD+ FE F LH+E I++DP RLVGQ+HD S+ N+
Sbjct: 121 HRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANF 180
Query: 181 SMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGENV 240
S+G M ALAGTYRC+GSVTH PY+LSAPSDPLDIVV GLY KPSLSAQPGP VQAGE+V
Sbjct: 181 SIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESV 240
Query: 241 TLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFRAL 300
TLSCSSRS +D+YHLSRE A E RL AV +VN TFQA+FPLGP THGG YRCFGSFR
Sbjct: 241 TLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHS 300
Query: 301 PHAWSDPSDPLPVSVTGNS-----------------RHLHVLIGTSVVIIPFAILLFFLL 343
P+ WSDPSDPL VSVTGN RHLH+LIGTSVV IPF ILLFFLL
Sbjct: 301 PYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNLRHLHILIGTSVVKIPFTILLFFLL 360
Query: 344 HRWCANKK 351
HRWC+NKK
Sbjct: 361 HRWCSNKK 368
>gi|62632748 killer-cell Ig-like receptor [Homo sapiens]
Length = 328
Score = 524 bits (1350), Expect = e-149
Identities = 252/320 (78%), Positives = 273/320 (85%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60
MSLMV+SMACVGFFLL+G W H GGQDKPFLSAWP VVSEG+HV LQCRSRLGFNEFSL
Sbjct: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPFLSAWPSPVVSEGEHVALQCRSRLGFNEFSL 60
Query: 61 SKEDGMPVPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGV 120
SKEDGMPVPELYNR+FRN+ +GPVTPAHAGTYRC SHPH TGWSAPSNP+VIMVTGV
Sbjct: 61 SKEDGMPVPELYNRVFRNTVFIGPVTPAHAGTYRCRGSHPHFLTGWSAPSNPLVIMVTGV 120
Query: 121 HRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNY 180
HRKPSLLAHPGPLVKS ETVILQCWSDV FE FLLHREG D LRL G+LHD S+ N+
Sbjct: 121 HRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLLHREGKFNDTLRLTGELHDGVSKANF 180
Query: 181 SMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGENV 240
S+G MT LAGTYRC+GSV H PY+LSAPSDPLDIV+ GL GKPSLSAQP P V+AGE+V
Sbjct: 181 SIGRMTQDLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLCGKPSLSAQPRPMVKAGESV 240
Query: 241 TLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFRAL 300
TLSCSSRS +DIYHLSRE EA ELR AV +VNGTFQANFPLGP THGG YRCFGSFR
Sbjct: 241 TLSCSSRSSYDIYHLSREGEAHELRFPAVPKVNGTFQANFPLGPATHGGTYRCFGSFRDS 300
Query: 301 PHAWSDPSDPLPVSVTGNSR 320
P+ WSD SDPL VSVT + +
Sbjct: 301 PYEWSDLSDPLLVSVTDSMK 320
>gi|71143139 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 3 isoform 2 [Homo sapiens]
Length = 341
Score = 476 bits (1226), Expect = e-134
Identities = 236/309 (76%), Positives = 255/309 (82%), Gaps = 17/309 (5%)
Query: 119 GVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQV 178
GVHRKPSLLAHPGPLVKS ETVILQCWSDVRF+ FLLHREG +D L L+G+ HD S+
Sbjct: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83
Query: 179 NYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGE 238
N+S+GPM LAGTYRC+GSVTH PY+LSAPSDPLDIV+ GLY KPSLSAQPGPTV AGE
Sbjct: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGE 143
Query: 239 NVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFR 298
+VTLSCSSRS +D+YHLSRE EA E R +A +VNGTFQA+FPLGP THGG YRCFGSFR
Sbjct: 144 SVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFR 203
Query: 299 ALPHAWSDPSDPLPVSV-----------------TGNSRHLHVLIGTSVVIIPFAILLFF 341
P+ WS+ SDPL VSV TGN RHLHVLIGTSVVII F +LLFF
Sbjct: 204 DSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSETGNPRHLHVLIGTSVVIILFILLLFF 263
Query: 342 LLHRWCANKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRP 401
LLHRWC NKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRP
Sbjct: 264 LLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRP 323
Query: 402 KTPPTDTSV 410
KTPPTD V
Sbjct: 324 KTPPTDIIV 332
Score = 179 bits (455), Expect = 3e-45
Identities = 106/243 (43%), Positives = 140/243 (57%), Gaps = 11/243 (4%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60
MSLMVVSM CVGFFLL+G WPH G KP L A PG +V + V LQC S + F F L
Sbjct: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60
Query: 61 SKEDGMP-----VPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVI 115
+E + E ++ + + +F +GP+ AGTYRC S HSP SAPS+P+ I
Sbjct: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
Query: 116 MVTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAG 175
++TG++ KPSL A PGP V +GE+V L C S ++ + L REG + G +
Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGT 180
Query: 176 SQVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQ 235
Q ++ +GP T GTYRCFGS PYE S SDPL +V + G PS ++ P PT
Sbjct: 181 FQADFPLGPATH--GGTYRCFGSFRDSPYEWSNSSDPL---LVSVTGNPS-NSWPSPTEP 234
Query: 236 AGE 238
+ E
Sbjct: 235 SSE 237
>gi|134304833 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 2 precursor [Homo sapiens]
Length = 348
Score = 461 bits (1186), Expect = e-130
Identities = 231/309 (74%), Positives = 250/309 (80%), Gaps = 18/309 (5%)
Query: 119 GVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQV 178
GVHRKPSLLAHPG LVKS ETVILQCWSDVRFE FLLHREG +D L L+G+ HD S+
Sbjct: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEHHDGVSKA 83
Query: 179 NYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGE 238
N+S+GPM LAGTYRC+GSVTH PY+LSAPSDPLDIV+ GLY KPSLSAQPGPTV AGE
Sbjct: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGE 143
Query: 239 NVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFR 298
+VTLSCSSRS +D+YHLSRE EA E R +A +VNGTFQA+FPLGP THGG YRCFGSFR
Sbjct: 144 SVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFR 203
Query: 299 ALPHAWSDPSDPLPVSV-----------------TGNSRHLHVLIGTSVVIIPFAILLFF 341
P+ WS+ SDPL VSV TGN RHLH+LIGTSVVII F ILLFF
Sbjct: 204 DSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGNPRHLHILIGTSVVIILF-ILLFF 262
Query: 342 LLHRWCANKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRP 401
LLHRWC+NKKNA VMDQE AGNRT N EDSDEQDPQEVTY QLNHCVFTQRKITRPSQRP
Sbjct: 263 LLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRP 322
Query: 402 KTPPTDTSV 410
KTPPTD V
Sbjct: 323 KTPPTDIIV 331
Score = 179 bits (455), Expect = 3e-45
Identities = 106/238 (44%), Positives = 139/238 (58%), Gaps = 11/238 (4%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60
MSLMVVSMACVGFFLL+G WPH G KP L A PG +V + V LQC S + F F L
Sbjct: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLL 60
Query: 61 SKEDGMP-----VPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVI 115
+E + E ++ + + +F +GP+ AGTYRC S HSP SAPS+P+ I
Sbjct: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
Query: 116 MVTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAG 175
++TG++ KPSL A PGP V +GE+V L C S ++ + L REG + G +
Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGT 180
Query: 176 SQVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPT 233
Q ++ +GP T GTYRCFGS PYE S SDPL +V + G PS ++ P PT
Sbjct: 181 FQADFPLGPATH--GGTYRCFGSFRDSPYEWSNSSDPL---LVSVTGNPS-NSWPSPT 232
>gi|110611923 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 1 [Homo sapiens]
Length = 348
Score = 454 bits (1168), Expect = e-128
Identities = 229/309 (74%), Positives = 247/309 (79%), Gaps = 18/309 (5%)
Query: 119 GVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQV 178
GVHRKPSLLAHPG LVKS ETVILQCWSDV FE FLLHREG+ D LRL+G+ HD S+
Sbjct: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGMFNDTLRLIGEHHDGVSKA 83
Query: 179 NYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGE 238
N+S+ MT LAGTYRC+GSVTH PY++SAPSDPLDIV++GLY KPSLSAQ GPTV AGE
Sbjct: 84 NFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDIVIIGLYEKPSLSAQLGPTVLAGE 143
Query: 239 NVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFR 298
NVTLSCSSRS +D+YHLSRE EA E RL A +VNGTFQA+FPLGP THGG YRCFGSF
Sbjct: 144 NVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGTFQADFPLGPATHGGTYRCFGSFH 203
Query: 299 ALPHAWSDPSDPLPVSV-----------------TGNSRHLHVLIGTSVVIIPFAILLFF 341
P+ WS SDPL VSV TGN RHLH+LIGTSVVII F ILLFF
Sbjct: 204 DSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGNPRHLHILIGTSVVIILF-ILLFF 262
Query: 342 LLHRWCANKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRP 401
LLHRWC+NKKNA VMDQE AGNRT N EDSDEQDPQEVTY QLNHCVFTQRKITRPSQRP
Sbjct: 263 LLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRP 322
Query: 402 KTPPTDTSV 410
KTPPTD V
Sbjct: 323 KTPPTDIIV 331
Score = 167 bits (424), Expect = 1e-41
Identities = 104/239 (43%), Positives = 137/239 (57%), Gaps = 13/239 (5%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60
MSL+VVSMACVGFFLL+G WPH G KP L A PG +V + V LQC S + F F L
Sbjct: 1 MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
Query: 61 SKEDGM------PVPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVV 114
+E GM + E ++ + + +F + +T AGTYRC S HSP SAPS+P+
Sbjct: 61 HRE-GMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLD 119
Query: 115 IMVTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDA 174
I++ G++ KPSL A GP V +GE V L C S ++ + L REG + G +
Sbjct: 120 IVIIGLYEKPSLSAQLGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNG 179
Query: 175 GSQVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPT 233
Q ++ +GP T GTYRCFGS PYE S SDPL +V + G PS ++ P PT
Sbjct: 180 TFQADFPLGPATH--GGTYRCFGSFHDSPYEWSKSSDPL---LVSVTGNPS-NSWPSPT 232
>gi|6912472 killer cell immunoglobulin-like receptor, two domains,
short cytoplasmic tail, 2 precursor [Homo sapiens]
Length = 304
Score = 417 bits (1073), Expect = e-117
Identities = 208/281 (74%), Positives = 227/281 (80%), Gaps = 17/281 (6%)
Query: 119 GVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQV 178
GVHRKPSLLAHPGPLVKS ETVILQCWSDVRFE FLLHREG +D L L+G+ HD S+
Sbjct: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFEHFLLHREGKYKDTLHLIGEHHDGVSKA 83
Query: 179 NYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGE 238
N+S+GPM LAGTYRC+GSVTH PY+LSAPSDPLDIV+ GLY KPSLSAQPGPTV AGE
Sbjct: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGE 143
Query: 239 NVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFR 298
+VTLSCSSRS +D+YHLSRE EA E R +A +VNGTFQA+FPLGP THGG YRCFGSFR
Sbjct: 144 SVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFR 203
Query: 299 ALPHAWSDPSDPLPVSV-----------------TGNSRHLHVLIGTSVVIIPFAILLFF 341
P+ WS+ SDPL VSV TGN RHLHVLIGTSVV IPF ILLFF
Sbjct: 204 DSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGNPRHLHVLIGTSVVKIPFTILLFF 263
Query: 342 LLHRWCANKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYA 382
LLHRWC+NKKNA VMDQEPAGNRTVN EDSDEQD QEV+YA
Sbjct: 264 LLHRWCSNKKNAAVMDQEPAGNRTVNSEDSDEQDHQEVSYA 304
Score = 179 bits (455), Expect = 3e-45
Identities = 106/238 (44%), Positives = 139/238 (58%), Gaps = 11/238 (4%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60
MSLMVVSMACVGFFLL+G WPH G KP L A PG +V + V LQC S + F F L
Sbjct: 1 MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFEHFLL 60
Query: 61 SKEDGMP-----VPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVI 115
+E + E ++ + + +F +GP+ AGTYRC S HSP SAPS+P+ I
Sbjct: 61 HREGKYKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
Query: 116 MVTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAG 175
++TG++ KPSL A PGP V +GE+V L C S ++ + L REG + G +
Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGT 180
Query: 176 SQVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPT 233
Q ++ +GP T GTYRCFGS PYE S SDPL +V + G PS ++ P PT
Sbjct: 181 FQADFPLGPATH--GGTYRCFGSFRDSPYEWSNSSDPL---LVSVTGNPS-NSWPSPT 232
>gi|7657277 killer cell immunoglobulin-like receptor, two domains,
short cytoplasmic tail, 1 precursor [Homo sapiens]
Length = 304
Score = 413 bits (1061), Expect = e-115
Identities = 207/281 (73%), Positives = 224/281 (79%), Gaps = 17/281 (6%)
Query: 119 GVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQV 178
GVHRKPSLLAHPG LVKS ETVILQCWSDV FE FLLHREG+ D LRL+G+ HD S+
Sbjct: 24 GVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGMFNDTLRLIGEHHDGVSKA 83
Query: 179 NYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGE 238
N+S+ M LAGTYRC+GSVTH PY+LSAPSDPLDIV++GLY KPSLSAQPGPTV AGE
Sbjct: 84 NFSISRMKQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVIIGLYEKPSLSAQPGPTVLAGE 143
Query: 239 NVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFR 298
NVTLSCSSRS +D+YHLSRE EA E RL A +VNGTFQANFPLGP THGG YRCFGSFR
Sbjct: 144 NVTLSCSSRSSYDMYHLSREGEAHERRLPAGTKVNGTFQANFPLGPATHGGTYRCFGSFR 203
Query: 299 ALPHAWSDPSDPLPVSV-----------------TGNSRHLHVLIGTSVVIIPFAILLFF 341
P+ WS SDPL VSV TGN RHLHVLIGTSVV IPF ILLFF
Sbjct: 204 DSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSETGNPRHLHVLIGTSVVKIPFTILLFF 263
Query: 342 LLHRWCANKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYA 382
LLHRWC++KKNA VMDQEPAGNRTVN EDSDEQD QEV+YA
Sbjct: 264 LLHRWCSDKKNAAVMDQEPAGNRTVNSEDSDEQDHQEVSYA 304
Score = 172 bits (435), Expect = 6e-43
Identities = 106/244 (43%), Positives = 138/244 (56%), Gaps = 13/244 (5%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60
MSL VVSMACVGFFLL+G WPH G KP L A PG +V + V LQC S + F F L
Sbjct: 1 MSLTVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
Query: 61 SKEDGM------PVPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVV 114
+E GM + E ++ + + +F + + AGTYRC S HSP SAPS+P+
Sbjct: 61 HRE-GMFNDTLRLIGEHHDGVSKANFSISRMKQDLAGTYRCYGSVTHSPYQLSAPSDPLD 119
Query: 115 IMVTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDA 174
I++ G++ KPSL A PGP V +GE V L C S ++ + L REG + G +
Sbjct: 120 IVIIGLYEKPSLSAQPGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGTKVNG 179
Query: 175 GSQVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTV 234
Q N+ +GP T GTYRCFGS PYE S SDPL +V + G PS ++ P PT
Sbjct: 180 TFQANFPLGPATH--GGTYRCFGSFRDSPYEWSKSSDPL---LVSVTGNPS-NSWPSPTE 233
Query: 235 QAGE 238
+ E
Sbjct: 234 PSSE 237
>gi|116517309 killer cell immunoglobulin-like receptor, two domains,
short cytoplasmic tail, 4 [Homo sapiens]
Length = 304
Score = 410 bits (1055), Expect = e-115
Identities = 204/281 (72%), Positives = 224/281 (79%), Gaps = 17/281 (6%)
Query: 119 GVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQV 178
GVHRKPS LA PG LVKS ETVILQCWSDV FE FLLHREG + L L+G+ HD S+
Sbjct: 24 GVHRKPSFLALPGHLVKSEETVILQCWSDVMFEHFLLHREGKFNNTLHLIGEHHDGVSKA 83
Query: 179 NYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGE 238
N+S+GPM P LAGTYRC+GSV H PY+LSAPSDPLD+V++GLY KPSLSAQPGPTVQAGE
Sbjct: 84 NFSIGPMMPVLAGTYRCYGSVPHSPYQLSAPSDPLDMVIIGLYEKPSLSAQPGPTVQAGE 143
Query: 239 NVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFR 298
NVTLSCSSRS +D+YHLSRE EA E RL AV +NGTFQA+FPLGP THGG YRCFGSFR
Sbjct: 144 NVTLSCSSRSSYDMYHLSREGEAHERRLPAVRSINGTFQADFPLGPATHGGTYRCFGSFR 203
Query: 299 ALPHAWSDPSDPLPVSV-----------------TGNSRHLHVLIGTSVVIIPFAILLFF 341
P+ WS+ SDPL VSV TGN RHLHVLIGTSVV IPF ILLFF
Sbjct: 204 DAPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGNPRHLHVLIGTSVVKIPFTILLFF 263
Query: 342 LLHRWCANKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYA 382
LLHRWC++KKNA VMDQEPAGNRTVN EDSDEQD QEV+YA
Sbjct: 264 LLHRWCSDKKNAAVMDQEPAGNRTVNSEDSDEQDHQEVSYA 304
Score = 173 bits (439), Expect = 2e-43
Identities = 101/238 (42%), Positives = 137/238 (57%), Gaps = 11/238 (4%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60
MSLMV+ MACVGFFLL+G WP G KP A PG +V + V LQC S + F F L
Sbjct: 1 MSLMVIIMACVGFFLLQGAWPQEGVHRKPSFLALPGHLVKSEETVILQCWSDVMFEHFLL 60
Query: 61 SKEDGMP-----VPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVI 115
+E + E ++ + + +F +GP+ P AGTYRC S PHSP SAPS+P+ +
Sbjct: 61 HREGKFNNTLHLIGEHHDGVSKANFSIGPMMPVLAGTYRCYGSVPHSPYQLSAPSDPLDM 120
Query: 116 MVTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAG 175
++ G++ KPSL A PGP V++GE V L C S ++ + L REG + + +
Sbjct: 121 VIIGLYEKPSLSAQPGPTVQAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAVRSINGT 180
Query: 176 SQVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPT 233
Q ++ +GP T GTYRCFGS PYE S SDPL +V + G PS ++ P PT
Sbjct: 181 FQADFPLGPATH--GGTYRCFGSFRDAPYEWSNSSDPL---LVSVTGNPS-NSWPSPT 232
>gi|134304835 killer cell immunoglobulin-like receptor, two domains,
short cytoplasmic tail, 5 [Homo sapiens]
Length = 304
Score = 397 bits (1021), Expect = e-111
Identities = 203/281 (72%), Positives = 220/281 (78%), Gaps = 17/281 (6%)
Query: 119 GVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQV 178
G RKPSLLAHPGPLVKS ETVILQCWSDV FE FLLHREG LRL+G+ D S+
Sbjct: 24 GFRRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLLHREGTFNHTLRLIGEHIDGVSKG 83
Query: 179 NYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGE 238
N+S+G MT LAGTYRC+GSVTH PY+LSAPSDPLDIV+ GLY KPSLSAQPGPTV AGE
Sbjct: 84 NFSIGRMTQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGE 143
Query: 239 NVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFR 298
+VTLSCSSRS +D+YHLSRE EA E RL A +VN TFQA+FPL P THGG YRCFGSFR
Sbjct: 144 SVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNRTFQADFPLDPATHGGTYRCFGSFR 203
Query: 299 ALPHAWSDPSDPLPVSVTGNS-----------------RHLHVLIGTSVVIIPFAILLFF 341
P+ WS SDPL VSVTGNS RHLHVLIGTSVV +PF ILLFF
Sbjct: 204 DSPYEWSKSSDPLLVSVTGNSSNSWPSPTEPSSETGNPRHLHVLIGTSVVKLPFTILLFF 263
Query: 342 LLHRWCANKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYA 382
LLHRWC+NKKNA VMDQ PAGNRTVNREDSDEQD QEV+YA
Sbjct: 264 LLHRWCSNKKNASVMDQGPAGNRTVNREDSDEQDHQEVSYA 304
Score = 172 bits (437), Expect = 4e-43
Identities = 103/243 (42%), Positives = 137/243 (56%), Gaps = 11/243 (4%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60
MSLMV+SMACV FFLL+G WPH G + KP L A PG +V + V LQC S + F F L
Sbjct: 1 MSLMVISMACVAFFLLQGAWPHEGFRRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLL 60
Query: 61 SKEDGMP-----VPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVI 115
+E + E + + + +F +G +T AGTYRC S HSP SAPS+P+ I
Sbjct: 61 HREGTFNHTLRLIGEHIDGVSKGNFSIGRMTQDLAGTYRCYGSVTHSPYQLSAPSDPLDI 120
Query: 116 MVTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAG 175
++TG++ KPSL A PGP V +GE+V L C S ++ + L REG + G +
Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNRT 180
Query: 176 SQVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQ 235
Q ++ + P T GTYRCFGS PYE S SDPL + V G S ++ P PT
Sbjct: 181 FQADFPLDPATH--GGTYRCFGSFRDSPYEWSKSSDPLLVSVTG----NSSNSWPSPTEP 234
Query: 236 AGE 238
+ E
Sbjct: 235 SSE 237
>gi|6912474 killer cell immunoglobulin-like receptor, two domains,
short cytoplasmic tail, 3 [Homo sapiens]
Length = 304
Score = 382 bits (982), Expect = e-106
Identities = 195/281 (69%), Positives = 214/281 (76%), Gaps = 17/281 (6%)
Query: 119 GVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQV 178
G RKPSLLAHPG LVKS ETVILQCWSDV FE FLLHREG D LRL+G+ D S+
Sbjct: 24 GFRRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGTFNDTLRLIGEHIDGVSKA 83
Query: 179 NYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGE 238
N+S+G M LAGTYRC+GSV H PY+ SAPSDPLDIV+ GLY KPSLSAQPGPTV AGE
Sbjct: 84 NFSIGRMRQDLAGTYRCYGSVPHSPYQFSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGE 143
Query: 239 NVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFR 298
+VTLSCSS S +D+YHLS E EA E R +A +VNGTFQA+FPLGP T GG YRCFGSF
Sbjct: 144 SVTLSCSSWSSYDMYHLSTEGEAHERRFSAGPKVNGTFQADFPLGPATQGGTYRCFGSFH 203
Query: 299 ALPHAWSDPSDPLPVSV-----------------TGNSRHLHVLIGTSVVIIPFAILLFF 341
P+ WS SDPL VSV TGN RHLHVLIGTSVV +PF ILLFF
Sbjct: 204 DSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGNPRHLHVLIGTSVVKLPFTILLFF 263
Query: 342 LLHRWCANKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYA 382
LLHRWC++KKNA VMDQ PAGNRTVNREDSDEQD QEV+YA
Sbjct: 264 LLHRWCSDKKNASVMDQGPAGNRTVNREDSDEQDHQEVSYA 304
Score = 174 bits (440), Expect = 2e-43
Identities = 103/238 (43%), Positives = 138/238 (57%), Gaps = 11/238 (4%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60
MSLMV+SMACVGFF L+G WPH G + KP L A PG +V + V LQC S + F F L
Sbjct: 1 MSLMVISMACVGFFWLQGAWPHEGFRRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLL 60
Query: 61 SKEDGMP-----VPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVI 115
+E + E + + + +F +G + AGTYRC S PHSP +SAPS+P+ I
Sbjct: 61 HREGTFNDTLRLIGEHIDGVSKANFSIGRMRQDLAGTYRCYGSVPHSPYQFSAPSDPLDI 120
Query: 116 MVTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAG 175
++TG++ KPSL A PGP V +GE+V L C S ++ + L EG + G +
Sbjct: 121 VITGLYEKPSLSAQPGPTVLAGESVTLSCSSWSSYDMYHLSTEGEAHERRFSAGPKVNGT 180
Query: 176 SQVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPT 233
Q ++ +GP T GTYRCFGS PYE S SDPL +V + G PS ++ P PT
Sbjct: 181 FQADFPLGPATQ--GGTYRCFGSFHDSPYEWSKSSDPL---LVSVTGNPS-NSWPSPT 232
>gi|11968154 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 5A [Homo sapiens]
Length = 375
Score = 363 bits (933), Expect = e-100
Identities = 196/309 (63%), Positives = 218/309 (70%), Gaps = 22/309 (7%)
Query: 119 GVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQV 178
G KP L A P +V G V L C S + F F L++E P +L++
Sbjct: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVPVP-----ELYNKIFWK 78
Query: 179 NYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGE 238
+ MGP+TPA AGTYRC GS P E SAPS+PL IVV GL+GKPSLSAQPGPTV+ GE
Sbjct: 79 SILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLFGKPSLSAQPGPTVRTGE 138
Query: 239 NVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFR 298
NVTLSCSSRS FD+YHLSRE A E RL AV VNGTFQA+FPLGP THGG Y CFGS
Sbjct: 139 NVTLSCSSRSSFDMYHLSREGRAHEPRLPAVPSVNGTFQADFPLGPATHGGTYTCFGSLH 198
Query: 299 ALPHAWSDPSDPLPVSVTGNS-----------------RHLHVLIGTSVVIIPFAILLFF 341
P+ WSDPSDPL VSVTGNS RHLH+LIGTSV II F IL FF
Sbjct: 199 DSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLHILIGTSVAIILFIILFFF 258
Query: 342 LLHRWCANKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRP 401
LLH C+NKKNA VMDQEPAG+RTVNREDSD+QDPQEVTYAQL+HCVFTQ KIT PSQRP
Sbjct: 259 LLHCCCSNKKNAAVMDQEPAGDRTVNREDSDDQDPQEVTYAQLDHCVFTQTKITSPSQRP 318
Query: 402 KTPPTDTSV 410
KTPPTDT++
Sbjct: 319 KTPPTDTTM 327
Score = 268 bits (684), Expect = 9e-72
Identities = 139/233 (59%), Positives = 158/233 (67%), Gaps = 6/233 (2%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60
MSLMV+SMACVGFFLL+G W H GGQDKP LSAWP VV G HVTL CRSRLGF FSL
Sbjct: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60
Query: 61 SKEDGMPVPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGV 120
KEDG+PVPELYN+IF S LMGPVTPAHAGTYRC SHP SP WSAPSNP+VI+VTG+
Sbjct: 61 YKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGL 120
Query: 121 HRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNY 180
KPSL A PGP V++GE V L C S F+ + L REG +P + Q ++
Sbjct: 121 FGKPSLSAQPGPTVRTGENVTLSCSSRSSFDMYHLSREGRAHEPRLPAVPSVNGTFQADF 180
Query: 181 SMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPT 233
+GP T GTY CFGS+ PYE S PSDPL + V G S S+ PT
Sbjct: 181 PLGPATH--GGTYTCFGSLHDSPYEWSDPSDPLLVSVTG----NSSSSSSSPT 227
>gi|124107606 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 4 isoform a [Homo sapiens]
Length = 377
Score = 353 bits (906), Expect = 2e-97
Identities = 188/309 (60%), Positives = 216/309 (69%), Gaps = 22/309 (7%)
Query: 119 GVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQV 178
G KP A P +V G V L+C F F L+++ P +L++
Sbjct: 26 GGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTLYKKDGVPVP-----ELYNRIFWN 80
Query: 179 NYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGE 238
++ + P+TPA AGTYRC G H P E SAPS+PL I+V GLY KPSL+A+PGPTV+AGE
Sbjct: 81 SFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGLYEKPSLTARPGPTVRAGE 140
Query: 239 NVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFR 298
NVTLSCSS+S FDIYHLSRE EA ELRL AV +NGTFQA+FPLGP THG YRCFGSF
Sbjct: 141 NVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADFPLGPATHGETYRCFGSFH 200
Query: 299 ALPHAWSDPSDPLPVSVTGN-----------------SRHLHVLIGTSVVIIPFAILLFF 341
P+ WSDPSDPLPVSVTGN +RHLH +I SV II F IL FF
Sbjct: 201 GSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKTGIARHLHAVIRYSVAIILFTILPFF 260
Query: 342 LLHRWCANKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRP 401
LLHRWC+ KKNA VM+QEPAG+RTVNREDSDEQDPQEVTYAQL+HC+FTQRKIT PSQR
Sbjct: 261 LLHRWCSKKKNAAVMNQEPAGHRTVNREDSDEQDPQEVTYAQLDHCIFTQRKITGPSQRS 320
Query: 402 KTPPTDTSV 410
K P TDTSV
Sbjct: 321 KRPSTDTSV 329
Score = 258 bits (660), Expect = 5e-69
Identities = 137/234 (58%), Positives = 161/234 (68%), Gaps = 8/234 (3%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60
MS V+ +AC+GFFL + W HVGGQDKPF SAWP VV +G HVTL+C R GFN F+L
Sbjct: 3 MSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTL 62
Query: 61 SKEDGMPVPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGV 120
K+DG+PVPELYNRIF NSFL+ PVTPAHAGTYRC HPHSPT WSAPSNP+VIMVTG+
Sbjct: 63 YKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGL 122
Query: 121 HRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGS-QVN 179
+ KPSL A PGP V++GE V L C S F+ + L REG + LRL G+ Q +
Sbjct: 123 YEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHE-LRLPAVPSINGTFQAD 181
Query: 180 YSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPT 233
+ +GP T TYRCFGS PYE S PSDPL + V G PS S+ P PT
Sbjct: 182 FPLGPATH--GETYRCFGSFHGSPYEWSDPSDPLPVSVT---GNPS-SSWPSPT 229
Score = 58.9 bits (141), Expect = 8e-09
Identities = 40/102 (39%), Positives = 49/102 (48%), Gaps = 7/102 (6%)
Query: 218 VGLYGKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQ 277
VG KP SA P V G +VTL C R F+I+ L ++ L N F
Sbjct: 25 VGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTLYKKDGVPVPEL-----YNRIFW 79
Query: 278 ANFPLGPVT--HGGNYRCFGSFRALPHAWSDPSDPLPVSVTG 317
+F + PVT H G YRC G P WS PS+PL + VTG
Sbjct: 80 NSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTG 121
>gi|66267727 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 5B precursor [Homo sapiens]
Length = 375
Score = 353 bits (905), Expect = 2e-97
Identities = 191/309 (61%), Positives = 214/309 (69%), Gaps = 22/309 (7%)
Query: 119 GVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQV 178
G KP L A P +V G V L C S + F F L++E P +L++
Sbjct: 24 GGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVPVP-----ELYNKIFWK 78
Query: 179 NYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGE 238
+ MGP+TPA AGTYRC GS P E SAPS+PL IVV GL+GKPSLSAQPGPTV+ GE
Sbjct: 79 SILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLFGKPSLSAQPGPTVRTGE 138
Query: 239 NVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFR 298
NV LSCSSRS FD+YHLSRE A E RL AV V+GTFQA+FPLGP THGG Y CF S
Sbjct: 139 NVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADFPLGPATHGGTYTCFSSLH 198
Query: 299 ALPHAWSDPSDPLPVSVTGNS-----------------RHLHVLIGTSVVIIPFAILLFF 341
P+ WSDPSDPL VSVTGNS RHLH+LIGTSV II F IL FF
Sbjct: 199 DSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLHILIGTSVAIILFIILFFF 258
Query: 342 LLHRWCANKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRP 401
LLH C+NKKNA VMDQ PAG+RTVNREDSD+QDPQEVTYAQL+HCVFTQ KIT PSQRP
Sbjct: 259 LLHCCCSNKKNAAVMDQGPAGDRTVNREDSDDQDPQEVTYAQLDHCVFTQTKITSPSQRP 318
Query: 402 KTPPTDTSV 410
K PPTDT++
Sbjct: 319 KAPPTDTTM 327
Score = 267 bits (683), Expect = 1e-71
Identities = 139/233 (59%), Positives = 157/233 (67%), Gaps = 6/233 (2%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60
MSLMV+SMACVGFFLL+G W H GGQDKP LSAWP VV G HVTL CRSRLGF FSL
Sbjct: 1 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSL 60
Query: 61 SKEDGMPVPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGV 120
KEDG+PVPELYN+IF S LMGPVTPAHAGTYRC SHP SP WSAPSNP+VI+VTG+
Sbjct: 61 YKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGL 120
Query: 121 HRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNY 180
KPSL A PGP V++GE V L C S F+ + L REG +P D Q ++
Sbjct: 121 FGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADF 180
Query: 181 SMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPT 233
+GP T GTY CF S+ PYE S PSDPL + V G S S+ PT
Sbjct: 181 PLGPATH--GGTYTCFSSLHDSPYEWSDPSDPLLVSVTG----NSSSSSSSPT 227
>gi|124107610 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 4 isoform c [Homo sapiens]
Length = 342
Score = 301 bits (772), Expect = 5e-82
Identities = 168/292 (57%), Positives = 194/292 (66%), Gaps = 23/292 (7%)
Query: 119 GVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQV 178
G KP A P +V G V L+C F F L+++ P +L++
Sbjct: 26 GGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTLYKKDGVPVP-----ELYNRIFWN 80
Query: 179 NYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGE 238
++ + P+TPA AGTYRC G H P E SAPS+PL I+V GLY KPSL+A+PGPTV+AGE
Sbjct: 81 SFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGLYEKPSLTARPGPTVRAGE 140
Query: 239 NVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFR 298
NVTLSCSS+S FDIYHLSRE EA ELRL AV +NGTFQA+FPLGP THG YRCFGSF
Sbjct: 141 NVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADFPLGPATHGETYRCFGSFH 200
Query: 299 ALPHAWSDPSDPLPVSVTGNSRHLHVLIGTSVVIIPFAILLFFLLHRWCANKKNAVVMDQ 358
P+ WSDPSDPLPVSVTGN P F K +A VM+Q
Sbjct: 201 GSPYEWSDPSDPLPVSVTGNPSSSW----------PSPTEPSF--------KTDAAVMNQ 242
Query: 359 EPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDTSV 410
EPAG+RTVNREDSDEQDPQEVTYAQL+HC+FTQRKIT PSQR K P TDTSV
Sbjct: 243 EPAGHRTVNREDSDEQDPQEVTYAQLDHCIFTQRKITGPSQRSKRPSTDTSV 294
Score = 258 bits (660), Expect = 5e-69
Identities = 137/234 (58%), Positives = 161/234 (68%), Gaps = 8/234 (3%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60
MS V+ +AC+GFFL + W HVGGQDKPF SAWP VV +G HVTL+C R GFN F+L
Sbjct: 3 MSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTL 62
Query: 61 SKEDGMPVPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGV 120
K+DG+PVPELYNRIF NSFL+ PVTPAHAGTYRC HPHSPT WSAPSNP+VIMVTG+
Sbjct: 63 YKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGL 122
Query: 121 HRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGS-QVN 179
+ KPSL A PGP V++GE V L C S F+ + L REG + LRL G+ Q +
Sbjct: 123 YEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHE-LRLPAVPSINGTFQAD 181
Query: 180 YSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPT 233
+ +GP T TYRCFGS PYE S PSDPL + V G PS S+ P PT
Sbjct: 182 FPLGPATH--GETYRCFGSFHGSPYEWSDPSDPLPVSVT---GNPS-SSWPSPT 229
Score = 58.9 bits (141), Expect = 8e-09
Identities = 40/102 (39%), Positives = 49/102 (48%), Gaps = 7/102 (6%)
Query: 218 VGLYGKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQ 277
VG KP SA P V G +VTL C R F+I+ L ++ L N F
Sbjct: 25 VGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTLYKKDGVPVPEL-----YNRIFW 79
Query: 278 ANFPLGPVT--HGGNYRCFGSFRALPHAWSDPSDPLPVSVTG 317
+F + PVT H G YRC G P WS PS+PL + VTG
Sbjct: 80 NSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTG 121
>gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B,
member 3 isoform 2 [Homo sapiens]
Length = 631
Score = 260 bits (664), Expect = 2e-69
Identities = 170/456 (37%), Positives = 245/456 (53%), Gaps = 81/456 (17%)
Query: 24 GGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKEDGMPVP------ELYNRIFR 77
G KP LSA P VV+ G ++TL+C S+ G++ F L KE +P +L++R F+
Sbjct: 119 GAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQ 178
Query: 78 NSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGVHRKPSLLAHPGPLVKSG 137
F +GPVTP+H + C + ++P WS PS+P+ I+ +GV RKPSLL GP++ G
Sbjct: 179 ALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPG 238
Query: 138 ETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAG-SQVNYSMGPMTPALAGTYRCF 196
+++ LQC SDV + RF+L++EG D L+ GQ AG SQ N+++GP++P+ G YRC+
Sbjct: 239 QSLTLQCGSDVGYNRFVLYKEG-ERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCY 297
Query: 197 GSVTHLPYELSAPSDPLDIVVVG-LYGKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHL 255
G+ +L E SAPSDPL+I++ G +Y SLSAQPGPTV +GENVTL C S FD + L
Sbjct: 298 GA-HNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLL 356
Query: 256 SREAEA-GELRLTAVLRVNGTFQANFPLGPVT--HGGNYRCFGSFRALPHAWSDPSDPLP 312
++E A LRL ++ + +QA FP+ PVT H G YRC+GS+ + PH S PS+PL
Sbjct: 357 TKEGAAHPPLRLRSMYGAH-KYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPLE 415
Query: 313 VSVTGNS-----------------RHLHVLIGTSVVIIPFAILLFFLL--------HRWC 347
+ V+G+S R+L VLIG SV + LL FLL HR
Sbjct: 416 LVVSGHSGGSSLPPTGPPSTPGLGRYLEVLIGVSVAFVLLLFLLLFLLLRRQRHSKHRTS 475
Query: 348 ANKKN----------------------------------AVVMDQEPAGNRTVNREDSDE 373
+K A V D + ++ + +
Sbjct: 476 DQRKTDFQRPAGAAETEPKDRGLLRRSSPAADVQEENLYAAVKDTQSEDRVELDSQSPHD 535
Query: 374 QDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDTS 409
+DPQ VTYA + H + P + +PP+ S
Sbjct: 536 EDPQAVTYAPVKH--------SSPRREMASPPSSLS 563
Score = 190 bits (483), Expect = 2e-48
Identities = 120/324 (37%), Positives = 174/324 (53%), Gaps = 12/324 (3%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60
M+ + ++ C+G L G KP L A PG+V+S G VT+ C+ E+ L
Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRL 60
Query: 61 SKEDGMPVPELYNRIF----RNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIM 116
KE G P P N + F + +T HAG YRC H +S GWS PS+P+ ++
Sbjct: 61 HKE-GSPEPLDRNNPLEPKNKARFSIPSMTEHHAGRYRC---HYYSSAGWSEPSDPLEMV 116
Query: 117 VTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVG-QLHDAG 175
+TG + KP+L A P P+V SG + L+C S + F+L +EG + P L QLH G
Sbjct: 117 MTGAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRG 176
Query: 176 SQVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQ 235
Q + +GP+TP+ + C+ T+ P+ S PSDPL+I+ G+ KPSL GP +
Sbjct: 177 FQALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLA 236
Query: 236 AGENVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPV--THGGNYRC 293
G+++TL C S ++ + L +E E L+ G QANF LGPV ++GG YRC
Sbjct: 237 PGQSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRC 296
Query: 294 FGSFRALPHAWSDPSDPLPVSVTG 317
+G+ L WS PSDPL + + G
Sbjct: 297 YGAHN-LSSEWSAPSDPLNILMAG 319
Score = 30.8 bits (68), Expect = 2.3
Identities = 14/54 (25%), Positives = 28/54 (51%)
Query: 357 DQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDTSV 410
D++ +R ++ E + + Q+VTYAQL+ ++ P + PP + S+
Sbjct: 571 DRQVEEDRQMDTEAAASEASQDVTYAQLHSLTLRRKATEPPPSQEGEPPAEPSI 624
>gi|124107604 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 4 isoform b [Homo sapiens]
Length = 273
Score = 258 bits (660), Expect = 5e-69
Identities = 137/234 (58%), Positives = 161/234 (68%), Gaps = 8/234 (3%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60
MS V+ +AC+GFFL + W HVGGQDKPF SAWP VV +G HVTL+C R GFN F+L
Sbjct: 3 MSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTL 62
Query: 61 SKEDGMPVPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGV 120
K+DG+PVPELYNRIF NSFL+ PVTPAHAGTYRC HPHSPT WSAPSNP+VIMVTG+
Sbjct: 63 YKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGL 122
Query: 121 HRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGS-QVN 179
+ KPSL A PGP V++GE V L C S F+ + L REG + LRL G+ Q +
Sbjct: 123 YEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHE-LRLPAVPSINGTFQAD 181
Query: 180 YSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPT 233
+ +GP T TYRCFGS PYE S PSDPL + V G PS S+ P PT
Sbjct: 182 FPLGPATH--GETYRCFGSFHGSPYEWSDPSDPLPVSVT---GNPS-SSWPSPT 229
Score = 251 bits (642), Expect = 6e-67
Identities = 138/250 (55%), Positives = 162/250 (64%), Gaps = 22/250 (8%)
Query: 119 GVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQV 178
G KP A P +V G V L+C F F L+++ P +L++
Sbjct: 26 GGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTLYKKDGVPVP-----ELYNRIFWN 80
Query: 179 NYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGE 238
++ + P+TPA AGTYRC G H P E SAPS+PL I+V GLY KPSL+A+PGPTV+AGE
Sbjct: 81 SFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGLYEKPSLTARPGPTVRAGE 140
Query: 239 NVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFR 298
NVTLSCSS+S FDIYHLSRE EA ELRL AV +NGTFQA+FPLGP THG YRCFGSF
Sbjct: 141 NVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADFPLGPATHGETYRCFGSFH 200
Query: 299 ALPHAWSDPSDPLPVSVTGN-----------------SRHLHVLIGTSVVIIPFAILLFF 341
P+ WSDPSDPLPVSVTGN +RHLH +I SV II F IL FF
Sbjct: 201 GSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKTGIARHLHAVIRYSVAIILFTILPFF 260
Query: 342 LLHRWCANKK 351
LLHRWC+ KK
Sbjct: 261 LLHRWCSKKK 270
Score = 58.9 bits (141), Expect = 8e-09
Identities = 40/102 (39%), Positives = 49/102 (48%), Gaps = 7/102 (6%)
Query: 218 VGLYGKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQ 277
VG KP SA P V G +VTL C R F+I+ L ++ L N F
Sbjct: 25 VGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTLYKKDGVPVPEL-----YNRIFW 79
Query: 278 ANFPLGPVT--HGGNYRCFGSFRALPHAWSDPSDPLPVSVTG 317
+F + PVT H G YRC G P WS PS+PL + VTG
Sbjct: 80 NSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTG 121
>gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B,
member 3 isoform 1 [Homo sapiens]
Length = 632
Score = 258 bits (658), Expect = 9e-69
Identities = 164/395 (41%), Positives = 231/395 (58%), Gaps = 43/395 (10%)
Query: 24 GGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKEDGMPVP------ELYNRIFR 77
G KP LSA P VV+ G ++TL+C S+ G++ F L KE +P +L++R F+
Sbjct: 119 GAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQ 178
Query: 78 NSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGVHRKPSLLAHPGPLVKSG 137
F +GPVTP+H + C + ++P WS PS+P+ I+ +GV RKPSLL GP++ G
Sbjct: 179 ALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPG 238
Query: 138 ETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAG-SQVNYSMGPMTPALAGTYRCF 196
+++ LQC SDV + RF+L++EG D L+ GQ AG SQ N+++GP++P+ G YRC+
Sbjct: 239 QSLTLQCGSDVGYNRFVLYKEG-ERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCY 297
Query: 197 GSVTHLPYELSAPSDPLDIVVVG-LYGKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHL 255
G+ +L E SAPSDPL+I++ G +Y SLSAQPGPTV +GENVTL C S FD + L
Sbjct: 298 GA-HNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLL 356
Query: 256 SREAEA-GELRLTAVLRVNGTFQANFPLGPVT--HGGNYRCFGSFRALPHAWSDPSDPLP 312
++E A LRL ++ + +QA FP+ PVT H G YRC+GS+ + PH S PS+PL
Sbjct: 357 TKEGAAHPPLRLRSMYGAH-KYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPLE 415
Query: 313 VSVTGNS-----------------RHLHVLIGTSVVIIPFAILLFFLLHRWCANKKNAVV 355
+ V+G+S R+L VLIG SV + LL FLL R + K+
Sbjct: 416 LVVSGHSGGSSLPPTGPPSTPGLGRYLEVLIGVSVAFVLLLFLLLFLLLRRQRHSKHRTS 475
Query: 356 MD-----QEPAG-------NRTVNREDSDEQDPQE 378
Q PAG +R + R S D QE
Sbjct: 476 DQRKTDFQRPAGAAETEPKDRGLLRRSSPAADVQE 510
Score = 190 bits (483), Expect = 2e-48
Identities = 120/324 (37%), Positives = 174/324 (53%), Gaps = 12/324 (3%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60
M+ + ++ C+G L G KP L A PG+V+S G VT+ C+ E+ L
Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRL 60
Query: 61 SKEDGMPVPELYNRIF----RNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIM 116
KE G P P N + F + +T HAG YRC H +S GWS PS+P+ ++
Sbjct: 61 HKE-GSPEPLDRNNPLEPKNKARFSIPSMTEHHAGRYRC---HYYSSAGWSEPSDPLEMV 116
Query: 117 VTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVG-QLHDAG 175
+TG + KP+L A P P+V SG + L+C S + F+L +EG + P L QLH G
Sbjct: 117 MTGAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRG 176
Query: 176 SQVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQ 235
Q + +GP+TP+ + C+ T+ P+ S PSDPL+I+ G+ KPSL GP +
Sbjct: 177 FQALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLA 236
Query: 236 AGENVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPV--THGGNYRC 293
G+++TL C S ++ + L +E E L+ G QANF LGPV ++GG YRC
Sbjct: 237 PGQSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRC 296
Query: 294 FGSFRALPHAWSDPSDPLPVSVTG 317
+G+ L WS PSDPL + + G
Sbjct: 297 YGAHN-LSSEWSAPSDPLNILMAG 319
Score = 30.8 bits (68), Expect = 2.3
Identities = 14/54 (25%), Positives = 28/54 (51%)
Query: 357 DQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDTSV 410
D++ +R ++ E + + Q+VTYAQL+ ++ P + PP + S+
Sbjct: 572 DRQVEEDRQMDTEAAASEASQDVTYAQLHSLTLRRKATEPPPSQEGEPPAEPSI 625
>gi|110611910 leukocyte immunoglobulin-like receptor, subfamily A,
member 6 [Homo sapiens]
Length = 481
Score = 246 bits (627), Expect = 4e-65
Identities = 139/307 (45%), Positives = 202/307 (65%), Gaps = 14/307 (4%)
Query: 24 GGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKEDGMPVP------ELYNRIFR 77
G +KP LSA P VV+ G ++TL+C S+ G++ F L KE +P +L++ F+
Sbjct: 119 GFYNKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGGFQ 178
Query: 78 NSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGVHRKPSLLAHPGPLVKSG 137
F +GPVTP+H + C + ++P WS PS+P+ I+ +GV RKPSLL GP++ G
Sbjct: 179 ALFPVGPVTPSHRWRFTCYYYYTNTPRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPG 238
Query: 138 ETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAG-SQVNYSMGPMTPALAGTYRCF 196
+++ LQC SDV ++RF+L++EG D L+ GQ AG SQ N+++GP++P+ G YRC+
Sbjct: 239 QSLTLQCGSDVGYDRFVLYKEG-ERDFLQRPGQQPQAGLSQANFTLGPVSPSHGGQYRCY 297
Query: 197 GSVTHLPYELSAPSDPLDIVVVG-LYGKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHL 255
G+ +L E SAPSDPL+I++ G +Y SLSAQPGPTV +GENVTL C SR FD + L
Sbjct: 298 GA-HNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSRGYFDTFLL 356
Query: 256 SREAEA-GELRLTAVLRVNGTFQANFPLGPVT--HGGNYRCFGSFRALPHAWSDPSDPLP 312
++E A LRL ++ + +QA FP+ PVT H G YRC+GS+ + PH S PS+PL
Sbjct: 357 TKEGAAHPPLRLRSMYGAH-KYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSFPSEPLE 415
Query: 313 VSVTGNS 319
+ V+G+S
Sbjct: 416 LMVSGHS 422
Score = 197 bits (501), Expect = 1e-50
Identities = 123/324 (37%), Positives = 174/324 (53%), Gaps = 12/324 (3%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60
M+ + ++ C+G L G KP L A PG+V+S G VT+ C+ L E+ L
Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSLEAQEYQL 60
Query: 61 SKEDGMPVPELYNRIF----RNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIM 116
KE G P P N + F + +T HAG YRC H +S GWS PS+P+ ++
Sbjct: 61 DKE-GSPEPLDRNNPLEPKNKARFSIPSMTQHHAGRYRC---HYYSSAGWSEPSDPLELV 116
Query: 117 VTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVG-QLHDAG 175
+TG + KP+L A P P+V SG + L+C S + F+L +EG + P L QLH G
Sbjct: 117 MTGFYNKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGG 176
Query: 176 SQVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQ 235
Q + +GP+TP+ + C+ T+ P S PSDPL+I+ G+ KPSL GP +
Sbjct: 177 FQALFPVGPVTPSHRWRFTCYYYYTNTPRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLA 236
Query: 236 AGENVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPV--THGGNYRC 293
G+++TL C S +D + L +E E L+ G QANF LGPV +HGG YRC
Sbjct: 237 PGQSLTLQCGSDVGYDRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSHGGQYRC 296
Query: 294 FGSFRALPHAWSDPSDPLPVSVTG 317
+G+ L WS PSDPL + + G
Sbjct: 297 YGAHN-LSSEWSAPSDPLNILMAG 319
Score = 149 bits (376), Expect = 4e-36
Identities = 90/219 (41%), Positives = 123/219 (56%), Gaps = 7/219 (3%)
Query: 24 GGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKEDGM-----PVPELYNRIFRN 78
G KP L G V++ GQ +TLQC S +G++ F L KE P + + +
Sbjct: 220 GVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYDRFVLYKEGERDFLQRPGQQPQAGLSQA 279
Query: 79 SFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTG-VHRKPSLLAHPGPLVKSG 137
+F +GPV+P+H G YRC +H S + WSAPS+P+ I++ G ++ SL A PGP V SG
Sbjct: 280 NFTLGPVSPSHGGQYRCYGAHNLS-SEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASG 338
Query: 138 ETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNYSMGPMTPALAGTYRCFG 197
E V L C S F+ FLL +EG PLRL Q + M P+T A AGTYRC+G
Sbjct: 339 ENVTLLCQSRGYFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYG 398
Query: 198 SVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQA 236
S + P+ LS PS+PL+++V G G SL P+ A
Sbjct: 399 SYSSNPHLLSFPSEPLELMVSGHSGGSSLPPTGPPSTPA 437
Score = 119 bits (298), Expect = 5e-27
Identities = 79/219 (36%), Positives = 113/219 (51%), Gaps = 8/219 (3%)
Query: 119 GVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQV 178
G KP+L A PG ++ G V + C + + + L +EG E PL L + ++
Sbjct: 24 GPFPKPTLWAEPGSVISWGSPVTIWCQGSLEAQEYQLDKEGSPE-PLDRNNPL-EPKNKA 81
Query: 179 NYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGE 238
+S+ MT AG YRC + S PSDPL++V+ G Y KP+LSA P P V +G
Sbjct: 82 RFSIPSMTQHHAGRYRCH---YYSSAGWSEPSDPLELVMTGFYNKPTLSALPSPVVASGG 138
Query: 239 NVTLSCSSRSLFDIYHLSREAEAGELR-LTAVLRVNGTFQANFPLGPVT--HGGNYRCFG 295
N+TL C S+ + + L +E E R L + +G FQA FP+GPVT H + C+
Sbjct: 139 NMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGGFQALFPVGPVTPSHRWRFTCYY 198
Query: 296 SFRALPHAWSDPSDPLPVSVTGNSRHLHVLIGTSVVIIP 334
+ P WS PSDPL + +G SR +L V+ P
Sbjct: 199 YYTNTPRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAP 237
>gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B,
member 2 isoform 2 [Homo sapiens]
Length = 597
Score = 241 bits (615), Expect = 9e-64
Identities = 164/475 (34%), Positives = 238/475 (50%), Gaps = 91/475 (19%)
Query: 24 GGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKEDGMPVPELYNR------IFR 77
G KP LSA P VV+ G VTLQC S++ F F L KE P+ N R
Sbjct: 119 GAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSR 178
Query: 78 NSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGVHRKPSLLAHPGPLVKSG 137
F +GPV+P ++RC +SP WS+PS+ + ++V GV +KPSL PGP+V G
Sbjct: 179 AIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPG 238
Query: 138 ETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAG-SQVNYSMGPMTPALAGTYRCF 196
E++ LQC SDV ++RF+L++EG D +L G+ AG SQ N+++GP++ + G YRC+
Sbjct: 239 ESLTLQCVSDVGYDRFVLYKEG-ERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCY 297
Query: 197 GSVTHLPYELSAPSDPLDIVVVG-LYGKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHL 255
G+ +L E SAPSDPLDI++ G + G P +S QPGPTV +GENVTL C S F + L
Sbjct: 298 GA-HNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLL 356
Query: 256 SREAEA-GELRLTAVLRVNGTFQANFPLGPVT--HGGNYRCFGSFRALPHAWSDPSDPLP 312
++ A LRL ++ +QA FP+ PVT H G YRC+GS + P+ S PS+PL
Sbjct: 357 TKAGAADAPLRLRSI-HEYPKYQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLE 415
Query: 313 VSVTGNS---------------------------------RHLHVLIG--TSVVIIPFAI 337
+ V+G S RHL V+IG +VV++ +
Sbjct: 416 LVVSGPSMGSSPPPTGPISTPGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVVLLLLLL 475
Query: 338 LLFFLLHR-------WCANKKN-----------------------------------AVV 355
LL FL+ R W + ++ A V
Sbjct: 476 LLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGLQWRSSPAADAQEENLYAAV 535
Query: 356 MDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDTSV 410
D +P ++ + + PQ+VTYAQL+ ++ P + + PP + S+
Sbjct: 536 KDTQPEDGVEMDTRAAASEAPQDVTYAQLHSLTLRRKATEPPPSQEREPPAEPSI 590
Score = 199 bits (506), Expect = 4e-51
Identities = 129/328 (39%), Positives = 183/328 (55%), Gaps = 14/328 (4%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHV--GGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEF 58
M+ +V + C+G L GP HV G KP L A P +V+++G VTL C+ L E+
Sbjct: 1 MTPIVTVLICLGLSL--GPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEY 58
Query: 59 SL--SKEDGMPVPELYNRIFRNS-FLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVI 115
L K+ + + + +N F + +T H G Y C +S WS S+P+V+
Sbjct: 59 RLYREKKSASWITRIRPELVKNGQFHIPSITWEHTGRYGC---QYYSRARWSELSDPLVL 115
Query: 116 MVTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAG 175
++TG + KP+L A P P+V SG V LQC S V F F+L +EG E P L Q H G
Sbjct: 116 VMTGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARG 175
Query: 176 S-QVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTV 234
S + +S+GP++P ++RC+G + PY S+PSD L+++V G+ KPSLS QPGP V
Sbjct: 176 SSRAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVV 235
Query: 235 QAGENVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPV--THGGNYR 292
GE++TL C S +D + L +E E +L G QANF LGPV ++GG YR
Sbjct: 236 APGESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYR 295
Query: 293 CFGSFRALPHAWSDPSDPLPVSVTGNSR 320
C+G+ L S PSDPL + +TG R
Sbjct: 296 CYGAHN-LSSECSAPSDPLDILITGQIR 322
Score = 94.7 bits (234), Expect = 1e-19
Identities = 70/221 (31%), Positives = 107/221 (48%), Gaps = 10/221 (4%)
Query: 118 TGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPL-RLVGQLHDAGS 176
TG KP+L A P ++ G V L C + + + L+RE + + R+ +L G
Sbjct: 23 TGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRLYREKKSASWITRIRPELVKNGQ 82
Query: 177 QVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQA 236
+ + +T G Y C + S SDPL +V+ G Y KP+LSAQP P V +
Sbjct: 83 ---FHIPSITWEHTGRYGC---QYYSRARWSELSDPLVLVMTGAYPKPTLSAQPSPVVTS 136
Query: 237 GENVTLSCSSRSLFDIYHLSREAEAGELR-LTAVLRVNGTFQANFPLGPVTHGG--NYRC 293
G VTL C S+ F + L +E E + L + G+ +A F +GPV+ ++RC
Sbjct: 137 GGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSRAIFSVGPVSPNRRWSHRC 196
Query: 294 FGSFRALPHAWSDPSDPLPVSVTGNSRHLHVLIGTSVVIIP 334
+G P+ WS PSD L + V G S+ + + V+ P
Sbjct: 197 YGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAP 237
>gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B,
member 2 isoform 1 [Homo sapiens]
Length = 598
Score = 241 bits (614), Expect = 1e-63
Identities = 164/476 (34%), Positives = 238/476 (50%), Gaps = 92/476 (19%)
Query: 24 GGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKEDGMPVPELYNR------IFR 77
G KP LSA P VV+ G VTLQC S++ F F L KE P+ N R
Sbjct: 119 GAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSR 178
Query: 78 NSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGVHRKPSLLAHPGPLVKSG 137
F +GPV+P ++RC +SP WS+PS+ + ++V GV +KPSL PGP+V G
Sbjct: 179 AIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPG 238
Query: 138 ETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAG-SQVNYSMGPMTPALAGTYRCF 196
E++ LQC SDV ++RF+L++EG D +L G+ AG SQ N+++GP++ + G YRC+
Sbjct: 239 ESLTLQCVSDVGYDRFVLYKEG-ERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCY 297
Query: 197 GSVTHLPYELSAPSDPLDIVVVG-LYGKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHL 255
G+ +L E SAPSDPLDI++ G + G P +S QPGPTV +GENVTL C S F + L
Sbjct: 298 GA-HNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLL 356
Query: 256 SREAEA-GELRLTAVLRVNGTFQANFPLGPVT--HGGNYRCFGSFRALPHAWSDPSDPLP 312
++ A LRL ++ +QA FP+ PVT H G YRC+GS + P+ S PS+PL
Sbjct: 357 TKAGAADAPLRLRSI-HEYPKYQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLE 415
Query: 313 VSVTGNS----------------------------------RHLHVLIG--TSVVIIPFA 336
+ V+G S RHL V+IG +VV++
Sbjct: 416 LVVSGPSMGSSPPPTGPISTPAGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVVLLLLL 475
Query: 337 ILLFFLLHR-------WCANKKN-----------------------------------AV 354
+LL FL+ R W + ++ A
Sbjct: 476 LLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGLQWRSSPAADAQEENLYAA 535
Query: 355 VMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDTSV 410
V D +P ++ + + PQ+VTYAQL+ ++ P + + PP + S+
Sbjct: 536 VKDTQPEDGVEMDTRAAASEAPQDVTYAQLHSLTLRRKATEPPPSQEREPPAEPSI 591
Score = 199 bits (506), Expect = 4e-51
Identities = 129/328 (39%), Positives = 183/328 (55%), Gaps = 14/328 (4%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHV--GGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEF 58
M+ +V + C+G L GP HV G KP L A P +V+++G VTL C+ L E+
Sbjct: 1 MTPIVTVLICLGLSL--GPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEY 58
Query: 59 SL--SKEDGMPVPELYNRIFRNS-FLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVI 115
L K+ + + + +N F + +T H G Y C +S WS S+P+V+
Sbjct: 59 RLYREKKSASWITRIRPELVKNGQFHIPSITWEHTGRYGC---QYYSRARWSELSDPLVL 115
Query: 116 MVTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAG 175
++TG + KP+L A P P+V SG V LQC S V F F+L +EG E P L Q H G
Sbjct: 116 VMTGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARG 175
Query: 176 S-QVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTV 234
S + +S+GP++P ++RC+G + PY S+PSD L+++V G+ KPSLS QPGP V
Sbjct: 176 SSRAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVV 235
Query: 235 QAGENVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPV--THGGNYR 292
GE++TL C S +D + L +E E +L G QANF LGPV ++GG YR
Sbjct: 236 APGESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYR 295
Query: 293 CFGSFRALPHAWSDPSDPLPVSVTGNSR 320
C+G+ L S PSDPL + +TG R
Sbjct: 296 CYGAHN-LSSECSAPSDPLDILITGQIR 322
Score = 94.7 bits (234), Expect = 1e-19
Identities = 70/221 (31%), Positives = 107/221 (48%), Gaps = 10/221 (4%)
Query: 118 TGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPL-RLVGQLHDAGS 176
TG KP+L A P ++ G V L C + + + L+RE + + R+ +L G
Sbjct: 23 TGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRLYREKKSASWITRIRPELVKNGQ 82
Query: 177 QVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQA 236
+ + +T G Y C + S SDPL +V+ G Y KP+LSAQP P V +
Sbjct: 83 ---FHIPSITWEHTGRYGC---QYYSRARWSELSDPLVLVMTGAYPKPTLSAQPSPVVTS 136
Query: 237 GENVTLSCSSRSLFDIYHLSREAEAGELR-LTAVLRVNGTFQANFPLGPVTHGG--NYRC 293
G VTL C S+ F + L +E E + L + G+ +A F +GPV+ ++RC
Sbjct: 137 GGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSRAIFSVGPVSPNRRWSHRC 196
Query: 294 FGSFRALPHAWSDPSDPLPVSVTGNSRHLHVLIGTSVVIIP 334
+G P+ WS PSD L + V G S+ + + V+ P
Sbjct: 197 YGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAP 237
>gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 4 [Homo sapiens]
Length = 651
Score = 239 bits (609), Expect = 4e-63
Identities = 164/474 (34%), Positives = 234/474 (49%), Gaps = 98/474 (20%)
Query: 24 GGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKEDGMPVPELYNR------IFR 77
G KP LSA P VV+ G +V LQC S++ F+ FSL KE P+ N R
Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179
Query: 78 NSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGVHRKPSLLAHPGPLVKSG 137
F +GPV+P+ YRC + +SP WS PS+ + ++V GV +KPSL PGP+V
Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239
Query: 138 ETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAG-SQVNYSMGPMTPALAGTYRCF 196
ET+ LQC SD + RF+L+++G D L+L G AG SQ N+++GP++ + G YRC+
Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDG-ERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCY 298
Query: 197 GSVTHLPYELSAPSDPLDIVVVG-LYGKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHL 255
G+ +L E SAPSDPLDI++ G Y + SLS QPGPTV +GENVTL C S+ + L
Sbjct: 299 GA-HNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLL 357
Query: 256 SREAEAGELRLTAVLRVNGTFQANFPLGPVT--HGGNYRCFGSFRALPHAWSDPSDPLPV 313
++E A + + +QA FP+GPVT H G YRC+GS + P+ + PSDPL +
Sbjct: 358 TKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLEL 417
Query: 314 SVTGNS---------------------------------RHLHVLIG--TSVVIIPFAIL 338
V+G S RHL V+IG +V+++ +L
Sbjct: 418 VVSGPSGGPSSPTTGPTSTSGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVILLLLLLL 477
Query: 339 LFFLLHR-------WCANKKN------------------------------------AVV 355
L FL+ R W + ++ AV
Sbjct: 478 LLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGLQWRSSPAADAQEENLYAAVK 537
Query: 356 MDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDTS 409
Q G R+ ++DPQ VTYA++ H +RP + +PP+ S
Sbjct: 538 HTQPEDGVEMDTRQSPHDEDPQAVTYAEVKH--------SRPRREMASPPSPLS 583
Score = 204 bits (519), Expect = 1e-52
Identities = 128/327 (39%), Positives = 185/327 (56%), Gaps = 17/327 (5%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHV--GGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEF 58
M+ ++ + C+G L GP HV G KP L A PG+V+++G VTL+C+ E+
Sbjct: 1 MTPILTVLICLGLSL--GPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEY 58
Query: 59 SLSKEDGMP-----VPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPV 113
L +E +P+ + + F + +T HAG YRC + G S S+P+
Sbjct: 59 RLYREKKTALWITRIPQ--ELVKKGQFPIPSITWEHAGRYRCY--YGSDTAGRSESSDPL 114
Query: 114 VIMVTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHD 173
++VTG + KP+L A P P+V SG VILQC S V F+ F L +EG E P L Q H
Sbjct: 115 ELVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHA 174
Query: 174 AGS-QVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGP 232
GS + +S+GP++P+ YRC+ ++ PYE S PSD L+++V+G+ KPSLS QPGP
Sbjct: 175 RGSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGP 234
Query: 233 TVQAGENVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPV--THGGN 290
V E +TL C S + ++ + L ++ E L+L G QANF LGPV ++GG
Sbjct: 235 IVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQ 294
Query: 291 YRCFGSFRALPHAWSDPSDPLPVSVTG 317
YRC+G+ L WS PSDPL + + G
Sbjct: 295 YRCYGAHN-LSSEWSAPSDPLDILIAG 320
Score = 155 bits (393), Expect = 5e-38
Identities = 92/221 (41%), Positives = 126/221 (57%), Gaps = 8/221 (3%)
Query: 23 VGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKEDGMPVPELYNR-----IFR 77
+G KP LS PG +V+ + +TLQC S G+N F L K+ +L + +
Sbjct: 220 LGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQ 279
Query: 78 NSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTG-VHRKPSLLAHPGPLVKS 136
+F +GPV+ ++ G YRC +H S + WSAPS+P+ I++ G + + SL PGP V S
Sbjct: 280 ANFTLGPVSRSYGGQYRCYGAHNLS-SEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVAS 338
Query: 137 GETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNYSMGPMTPALAGTYRCF 196
GE V L C S + FLL +EG +DP RL Q + MGP+T A AGTYRC+
Sbjct: 339 GENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCY 398
Query: 197 GSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAG 237
GS + PY L+ PSDPL++VV G G PS S GPT +G
Sbjct: 399 GSQSSKPYLLTHPSDPLELVVSGPSGGPS-SPTTGPTSTSG 438
Score = 107 bits (266), Expect = 3e-23
Identities = 77/221 (34%), Positives = 110/221 (49%), Gaps = 19/221 (8%)
Query: 123 KPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREG-----ITEDPLRLVGQLHDAGSQ 177
KP+L A PG ++ G V L+C + + L+RE IT P LV +
Sbjct: 28 KPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELV-------KK 80
Query: 178 VNYSMGPMTPALAGTYRCF-GSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQA 236
+ + +T AG YRC+ GS T S SDPL++VV G Y KP+LSAQP P V +
Sbjct: 81 GQFPIPSITWEHAGRYRCYYGSDTA---GRSESSDPLELVVTGAYIKPTLSAQPSPVVNS 137
Query: 237 GENVTLSCSSRSLFDIYHLSREAEAGELR-LTAVLRVNGTFQANFPLGPVTHGGN--YRC 293
G NV L C S+ FD + L +E E + L + G+ +A F +GPV+ YRC
Sbjct: 138 GGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRC 197
Query: 294 FGSFRALPHAWSDPSDPLPVSVTGNSRHLHVLIGTSVVIIP 334
+ P+ WS PSD L + V G S+ + + ++ P
Sbjct: 198 YAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAP 238
Score = 31.2 bits (69), Expect = 1.8
Identities = 16/48 (33%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Query: 357 DQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTP 404
D++ +R ++ E + + PQ+VTYAQL H + +R+ T P + P
Sbjct: 591 DRQAEEDRQMDTEAAASEAPQDVTYAQL-HSLTLRREATEPPPSQEGP 637
>gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 1 [Homo sapiens]
Length = 650
Score = 239 bits (609), Expect = 4e-63
Identities = 162/473 (34%), Positives = 234/473 (49%), Gaps = 97/473 (20%)
Query: 24 GGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKEDGMPVPELYNR------IFR 77
G KP LSA P VV+ G +V LQC S++ F+ FSL KE P+ N R
Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179
Query: 78 NSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGVHRKPSLLAHPGPLVKSG 137
F +GPV+P+ YRC + +SP WS PS+ + ++V GV +KPSL PGP+V
Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239
Query: 138 ETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAG-SQVNYSMGPMTPALAGTYRCF 196
ET+ LQC SD + RF+L+++G D L+L G AG SQ N+++GP++ + G YRC+
Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDG-ERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCY 298
Query: 197 GSVTHLPYELSAPSDPLDIVVVG-LYGKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHL 255
G+ +L E SAPSDPLDI++ G Y + SLS QPGPTV +GENVTL C S+ + L
Sbjct: 299 GA-HNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLL 357
Query: 256 SREAEAGELRLTAVLRVNGTFQANFPLGPVT--HGGNYRCFGSFRALPHAWSDPSDPLPV 313
++E A + + +QA FP+GPVT H G YRC+GS + P+ + PSDPL +
Sbjct: 358 TKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLEL 417
Query: 314 SVTGNS---------------------------------RHLHVLIG--TSVVIIPFAIL 338
V+G S RHL V+IG +V+++ +L
Sbjct: 418 VVSGPSGGPSSPTTGPTSTSGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVILLLLLLL 477
Query: 339 LFFLLHR-------WCANKKN-----------------------------------AVVM 356
L FL+ R W + ++ A V
Sbjct: 478 LLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGLQWRSSPAADAQEENLYAAVK 537
Query: 357 DQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDTS 409
+P ++ ++DPQ VTYA++ H +RP + +PP+ S
Sbjct: 538 HTQPEDGVEMDTRSPHDEDPQAVTYAEVKH--------SRPRREMASPPSPLS 582
Score = 204 bits (519), Expect = 1e-52
Identities = 128/327 (39%), Positives = 185/327 (56%), Gaps = 17/327 (5%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHV--GGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEF 58
M+ ++ + C+G L GP HV G KP L A PG+V+++G VTL+C+ E+
Sbjct: 1 MTPILTVLICLGLSL--GPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEY 58
Query: 59 SLSKEDGMP-----VPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPV 113
L +E +P+ + + F + +T HAG YRC + G S S+P+
Sbjct: 59 RLYREKKTALWITRIPQ--ELVKKGQFPIPSITWEHAGRYRCY--YGSDTAGRSESSDPL 114
Query: 114 VIMVTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHD 173
++VTG + KP+L A P P+V SG VILQC S V F+ F L +EG E P L Q H
Sbjct: 115 ELVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHA 174
Query: 174 AGS-QVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGP 232
GS + +S+GP++P+ YRC+ ++ PYE S PSD L+++V+G+ KPSLS QPGP
Sbjct: 175 RGSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGP 234
Query: 233 TVQAGENVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPV--THGGN 290
V E +TL C S + ++ + L ++ E L+L G QANF LGPV ++GG
Sbjct: 235 IVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQ 294
Query: 291 YRCFGSFRALPHAWSDPSDPLPVSVTG 317
YRC+G+ L WS PSDPL + + G
Sbjct: 295 YRCYGAHN-LSSEWSAPSDPLDILIAG 320
Score = 155 bits (393), Expect = 5e-38
Identities = 92/221 (41%), Positives = 126/221 (57%), Gaps = 8/221 (3%)
Query: 23 VGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKEDGMPVPELYNR-----IFR 77
+G KP LS PG +V+ + +TLQC S G+N F L K+ +L + +
Sbjct: 220 LGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQ 279
Query: 78 NSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTG-VHRKPSLLAHPGPLVKS 136
+F +GPV+ ++ G YRC +H S + WSAPS+P+ I++ G + + SL PGP V S
Sbjct: 280 ANFTLGPVSRSYGGQYRCYGAHNLS-SEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVAS 338
Query: 137 GETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNYSMGPMTPALAGTYRCF 196
GE V L C S + FLL +EG +DP RL Q + MGP+T A AGTYRC+
Sbjct: 339 GENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCY 398
Query: 197 GSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAG 237
GS + PY L+ PSDPL++VV G G PS S GPT +G
Sbjct: 399 GSQSSKPYLLTHPSDPLELVVSGPSGGPS-SPTTGPTSTSG 438
Score = 107 bits (266), Expect = 3e-23
Identities = 77/221 (34%), Positives = 110/221 (49%), Gaps = 19/221 (8%)
Query: 123 KPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREG-----ITEDPLRLVGQLHDAGSQ 177
KP+L A PG ++ G V L+C + + L+RE IT P LV +
Sbjct: 28 KPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELV-------KK 80
Query: 178 VNYSMGPMTPALAGTYRCF-GSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQA 236
+ + +T AG YRC+ GS T S SDPL++VV G Y KP+LSAQP P V +
Sbjct: 81 GQFPIPSITWEHAGRYRCYYGSDTA---GRSESSDPLELVVTGAYIKPTLSAQPSPVVNS 137
Query: 237 GENVTLSCSSRSLFDIYHLSREAEAGELR-LTAVLRVNGTFQANFPLGPVTHGGN--YRC 293
G NV L C S+ FD + L +E E + L + G+ +A F +GPV+ YRC
Sbjct: 138 GGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRC 197
Query: 294 FGSFRALPHAWSDPSDPLPVSVTGNSRHLHVLIGTSVVIIP 334
+ P+ WS PSD L + V G S+ + + ++ P
Sbjct: 198 YAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAP 238
Score = 31.2 bits (69), Expect = 1.8
Identities = 16/48 (33%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Query: 357 DQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTP 404
D++ +R ++ E + + PQ+VTYAQL H + +R+ T P + P
Sbjct: 590 DRQAEEDRQMDTEAAASEAPQDVTYAQL-HSLTLRREATEPPPSQEGP 636
>gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 3 [Homo sapiens]
Length = 651
Score = 238 bits (608), Expect = 6e-63
Identities = 162/474 (34%), Positives = 234/474 (49%), Gaps = 98/474 (20%)
Query: 24 GGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKEDGMPVPELYNR------IFR 77
G KP LSA P VV+ G +V LQC S++ F+ FSL KE P+ N R
Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179
Query: 78 NSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGVHRKPSLLAHPGPLVKSG 137
F +GPV+P+ YRC + +SP WS PS+ + ++V GV +KPSL PGP+V
Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239
Query: 138 ETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAG-SQVNYSMGPMTPALAGTYRCF 196
ET+ LQC SD + RF+L+++G D L+L G AG SQ N+++GP++ + G YRC+
Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDG-ERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCY 298
Query: 197 GSVTHLPYELSAPSDPLDIVVVG-LYGKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHL 255
G+ +L E SAPSDPLDI++ G Y + SLS QPGPTV +GENVTL C S+ + L
Sbjct: 299 GA-HNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLL 357
Query: 256 SREAEAGELRLTAVLRVNGTFQANFPLGPVT--HGGNYRCFGSFRALPHAWSDPSDPLPV 313
++E A + + +QA FP+GPVT H G YRC+GS + P+ + PSDPL +
Sbjct: 358 TKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLEL 417
Query: 314 SVTGNS----------------------------------RHLHVLIG--TSVVIIPFAI 337
V+G S RHL V+IG +V+++ +
Sbjct: 418 VVSGPSGGPSSPTTGPTSTSAGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVILLLLLL 477
Query: 338 LLFFLLHR-------WCANKKN-----------------------------------AVV 355
LL FL+ R W + ++ A V
Sbjct: 478 LLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGLQWRSSPAADAQEENLYAAV 537
Query: 356 MDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDTS 409
+P ++ ++DPQ VTYA++ H +RP + +PP+ S
Sbjct: 538 KHTQPEDGVEMDTRSPHDEDPQAVTYAEVKH--------SRPRREMASPPSPLS 583
Score = 204 bits (519), Expect = 1e-52
Identities = 128/327 (39%), Positives = 185/327 (56%), Gaps = 17/327 (5%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHV--GGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEF 58
M+ ++ + C+G L GP HV G KP L A PG+V+++G VTL+C+ E+
Sbjct: 1 MTPILTVLICLGLSL--GPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEY 58
Query: 59 SLSKEDGMP-----VPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPV 113
L +E +P+ + + F + +T HAG YRC + G S S+P+
Sbjct: 59 RLYREKKTALWITRIPQ--ELVKKGQFPIPSITWEHAGRYRCY--YGSDTAGRSESSDPL 114
Query: 114 VIMVTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHD 173
++VTG + KP+L A P P+V SG VILQC S V F+ F L +EG E P L Q H
Sbjct: 115 ELVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHA 174
Query: 174 AGS-QVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGP 232
GS + +S+GP++P+ YRC+ ++ PYE S PSD L+++V+G+ KPSLS QPGP
Sbjct: 175 RGSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGP 234
Query: 233 TVQAGENVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPV--THGGN 290
V E +TL C S + ++ + L ++ E L+L G QANF LGPV ++GG
Sbjct: 235 IVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQ 294
Query: 291 YRCFGSFRALPHAWSDPSDPLPVSVTG 317
YRC+G+ L WS PSDPL + + G
Sbjct: 295 YRCYGAHN-LSSEWSAPSDPLDILIAG 320
Score = 154 bits (389), Expect = 1e-37
Identities = 91/217 (41%), Positives = 124/217 (57%), Gaps = 8/217 (3%)
Query: 23 VGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKEDGMPVPELYNR-----IFR 77
+G KP LS PG +V+ + +TLQC S G+N F L K+ +L + +
Sbjct: 220 LGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQ 279
Query: 78 NSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTG-VHRKPSLLAHPGPLVKS 136
+F +GPV+ ++ G YRC +H S + WSAPS+P+ I++ G + + SL PGP V S
Sbjct: 280 ANFTLGPVSRSYGGQYRCYGAHNLS-SEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVAS 338
Query: 137 GETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNYSMGPMTPALAGTYRCF 196
GE V L C S + FLL +EG +DP RL Q + MGP+T A AGTYRC+
Sbjct: 339 GENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCY 398
Query: 197 GSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPT 233
GS + PY L+ PSDPL++VV G G PS S GPT
Sbjct: 399 GSQSSKPYLLTHPSDPLELVVSGPSGGPS-SPTTGPT 434
Score = 107 bits (266), Expect = 3e-23
Identities = 77/221 (34%), Positives = 110/221 (49%), Gaps = 19/221 (8%)
Query: 123 KPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREG-----ITEDPLRLVGQLHDAGSQ 177
KP+L A PG ++ G V L+C + + L+RE IT P LV +
Sbjct: 28 KPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELV-------KK 80
Query: 178 VNYSMGPMTPALAGTYRCF-GSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQA 236
+ + +T AG YRC+ GS T S SDPL++VV G Y KP+LSAQP P V +
Sbjct: 81 GQFPIPSITWEHAGRYRCYYGSDTA---GRSESSDPLELVVTGAYIKPTLSAQPSPVVNS 137
Query: 237 GENVTLSCSSRSLFDIYHLSREAEAGELR-LTAVLRVNGTFQANFPLGPVTHGGN--YRC 293
G NV L C S+ FD + L +E E + L + G+ +A F +GPV+ YRC
Sbjct: 138 GGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRC 197
Query: 294 FGSFRALPHAWSDPSDPLPVSVTGNSRHLHVLIGTSVVIIP 334
+ P+ WS PSD L + V G S+ + + ++ P
Sbjct: 198 YAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAP 238
Score = 31.2 bits (69), Expect = 1.8
Identities = 16/48 (33%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Query: 357 DQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTP 404
D++ +R ++ E + + PQ+VTYAQL H + +R+ T P + P
Sbjct: 591 DRQAEEDRQMDTEAAASEAPQDVTYAQL-HSLTLRREATEPPPSQEGP 637
>gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 2 [Homo sapiens]
Length = 652
Score = 238 bits (608), Expect = 6e-63
Identities = 164/475 (34%), Positives = 234/475 (49%), Gaps = 99/475 (20%)
Query: 24 GGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKEDGMPVPELYNR------IFR 77
G KP LSA P VV+ G +V LQC S++ F+ FSL KE P+ N R
Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179
Query: 78 NSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGVHRKPSLLAHPGPLVKSG 137
F +GPV+P+ YRC + +SP WS PS+ + ++V GV +KPSL PGP+V
Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239
Query: 138 ETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAG-SQVNYSMGPMTPALAGTYRCF 196
ET+ LQC SD + RF+L+++G D L+L G AG SQ N+++GP++ + G YRC+
Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDG-ERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCY 298
Query: 197 GSVTHLPYELSAPSDPLDIVVVG-LYGKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHL 255
G+ +L E SAPSDPLDI++ G Y + SLS QPGPTV +GENVTL C S+ + L
Sbjct: 299 GA-HNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLL 357
Query: 256 SREAEAGELRLTAVLRVNGTFQANFPLGPVT--HGGNYRCFGSFRALPHAWSDPSDPLPV 313
++E A + + +QA FP+GPVT H G YRC+GS + P+ + PSDPL +
Sbjct: 358 TKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLEL 417
Query: 314 SVTGNS----------------------------------RHLHVLIG--TSVVIIPFAI 337
V+G S RHL V+IG +V+++ +
Sbjct: 418 VVSGPSGGPSSPTTGPTSTSAGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVILLLLLL 477
Query: 338 LLFFLLHR-------WCANKKN------------------------------------AV 354
LL FL+ R W + ++ AV
Sbjct: 478 LLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGLQWRSSPAADAQEENLYAAV 537
Query: 355 VMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDTS 409
Q G R+ ++DPQ VTYA++ H +RP + +PP+ S
Sbjct: 538 KHTQPEDGVEMDTRQSPHDEDPQAVTYAEVKH--------SRPRREMASPPSPLS 584
Score = 204 bits (519), Expect = 1e-52
Identities = 128/327 (39%), Positives = 185/327 (56%), Gaps = 17/327 (5%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHV--GGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEF 58
M+ ++ + C+G L GP HV G KP L A PG+V+++G VTL+C+ E+
Sbjct: 1 MTPILTVLICLGLSL--GPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEY 58
Query: 59 SLSKEDGMP-----VPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPV 113
L +E +P+ + + F + +T HAG YRC + G S S+P+
Sbjct: 59 RLYREKKTALWITRIPQ--ELVKKGQFPIPSITWEHAGRYRCY--YGSDTAGRSESSDPL 114
Query: 114 VIMVTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHD 173
++VTG + KP+L A P P+V SG VILQC S V F+ F L +EG E P L Q H
Sbjct: 115 ELVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHA 174
Query: 174 AGS-QVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGP 232
GS + +S+GP++P+ YRC+ ++ PYE S PSD L+++V+G+ KPSLS QPGP
Sbjct: 175 RGSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGP 234
Query: 233 TVQAGENVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPV--THGGN 290
V E +TL C S + ++ + L ++ E L+L G QANF LGPV ++GG
Sbjct: 235 IVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQ 294
Query: 291 YRCFGSFRALPHAWSDPSDPLPVSVTG 317
YRC+G+ L WS PSDPL + + G
Sbjct: 295 YRCYGAHN-LSSEWSAPSDPLDILIAG 320
Score = 154 bits (389), Expect = 1e-37
Identities = 91/217 (41%), Positives = 124/217 (57%), Gaps = 8/217 (3%)
Query: 23 VGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKEDGMPVPELYNR-----IFR 77
+G KP LS PG +V+ + +TLQC S G+N F L K+ +L + +
Sbjct: 220 LGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQ 279
Query: 78 NSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTG-VHRKPSLLAHPGPLVKS 136
+F +GPV+ ++ G YRC +H S + WSAPS+P+ I++ G + + SL PGP V S
Sbjct: 280 ANFTLGPVSRSYGGQYRCYGAHNLS-SEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVAS 338
Query: 137 GETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNYSMGPMTPALAGTYRCF 196
GE V L C S + FLL +EG +DP RL Q + MGP+T A AGTYRC+
Sbjct: 339 GENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCY 398
Query: 197 GSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPT 233
GS + PY L+ PSDPL++VV G G PS S GPT
Sbjct: 399 GSQSSKPYLLTHPSDPLELVVSGPSGGPS-SPTTGPT 434
Score = 107 bits (266), Expect = 3e-23
Identities = 77/221 (34%), Positives = 110/221 (49%), Gaps = 19/221 (8%)
Query: 123 KPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREG-----ITEDPLRLVGQLHDAGSQ 177
KP+L A PG ++ G V L+C + + L+RE IT P LV +
Sbjct: 28 KPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELV-------KK 80
Query: 178 VNYSMGPMTPALAGTYRCF-GSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQA 236
+ + +T AG YRC+ GS T S SDPL++VV G Y KP+LSAQP P V +
Sbjct: 81 GQFPIPSITWEHAGRYRCYYGSDTA---GRSESSDPLELVVTGAYIKPTLSAQPSPVVNS 137
Query: 237 GENVTLSCSSRSLFDIYHLSREAEAGELR-LTAVLRVNGTFQANFPLGPVTHGGN--YRC 293
G NV L C S+ FD + L +E E + L + G+ +A F +GPV+ YRC
Sbjct: 138 GGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRC 197
Query: 294 FGSFRALPHAWSDPSDPLPVSVTGNSRHLHVLIGTSVVIIP 334
+ P+ WS PSD L + V G S+ + + ++ P
Sbjct: 198 YAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAP 238
Score = 31.2 bits (69), Expect = 1.8
Identities = 16/48 (33%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Query: 357 DQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTP 404
D++ +R ++ E + + PQ+VTYAQL H + +R+ T P + P
Sbjct: 592 DRQAEEDRQMDTEAAASEAPQDVTYAQL-HSLTLRREATEPPPSQEGP 638
>gi|71143143 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 3 isoform 1 [Homo sapiens]
Length = 243
Score = 238 bits (606), Expect = 1e-62
Identities = 129/211 (61%), Positives = 143/211 (67%), Gaps = 19/211 (9%)
Query: 219 GLYGKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQA 278
G++ KPSL A PGP V++ E V L C S F + L RE + + +G +A
Sbjct: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83
Query: 279 NFPLGPVTH--GGNYRCFGSFRALPHAWSDPSDPLPVSVTGNS----------------- 319
NF +GP+ G YRC+GS P+ S PSDPL VSVTGN
Sbjct: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLVSVTGNPSNSWPSPTEPSSETGNP 143
Query: 320 RHLHVLIGTSVVIIPFAILLFFLLHRWCANKKNAVVMDQEPAGNRTVNREDSDEQDPQEV 379
RHLHVLIGTSVVII F +LLFFLLHRWC NKKNAVVMDQEPAGNRTVNREDSDEQDPQEV
Sbjct: 144 RHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEV 203
Query: 380 TYAQLNHCVFTQRKITRPSQRPKTPPTDTSV 410
TYAQLNHCVFTQRKITRPSQRPKTPPTD V
Sbjct: 204 TYAQLNHCVFTQRKITRPSQRPKTPPTDIIV 234
Score = 161 bits (408), Expect = 9e-40
Identities = 80/120 (66%), Positives = 94/120 (78%), Gaps = 4/120 (3%)
Query: 119 GVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQV 178
GVHRKPSLLAHPGPLVKS ETVILQCWSDVRF+ FLLHREG +D L L+G+ HD S+
Sbjct: 24 GVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKA 83
Query: 179 NYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGE 238
N+S+GPM LAGTYRC+GSVTH PY+LSAPSDPL +V + G PS ++ P PT + E
Sbjct: 84 NFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPL---LVSVTGNPS-NSWPSPTEPSSE 139
Score = 108 bits (270), Expect = 9e-24
Identities = 65/144 (45%), Positives = 83/144 (57%), Gaps = 9/144 (6%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSL 60
MSLMVVSM CVGFFLL+G WPH G KP L A PG +V + V LQC S + F F L
Sbjct: 1 MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLL 60
Query: 61 SKEDGMP-----VPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVI 115
+E + E ++ + + +F +GP+ AGTYRC S HSP SAPS+P+++
Sbjct: 61 HREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLLV 120
Query: 116 MVTGVHRKPSLLAHPGPLVKSGET 139
VTG PS + P P S ET
Sbjct: 121 SVTG---NPS-NSWPSPTEPSSET 140
>gi|5803066 leukocyte immunoglobulin-like receptor, subfamily A
(with TM domain), member 1 [Homo sapiens]
Length = 489
Score = 225 bits (574), Expect = 5e-59
Identities = 134/310 (43%), Positives = 186/310 (60%), Gaps = 14/310 (4%)
Query: 24 GGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKEDGMPVPELYNRIFRNS---- 79
G KP LSA P VV+ G +VTL C S++ F F L KE P+ N R
Sbjct: 120 GAYIKPTLSALPSPVVTSGGNVTLHCVSQVAFGSFILCKEGEDEHPQCLNSQPRTHGWSR 179
Query: 80 --FLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGVHRKPSLLAHPGPLVKSG 137
F +GPV+P+ +YRC + +SP WS PS+ + ++V GV +KPSL PGP+V G
Sbjct: 180 AIFSVGPVSPSRRWSYRCYAYDSNSPHVWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPG 239
Query: 138 ETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAG-SQVNYSMGPMTPALAGTYRCF 196
E++ LQC SDV ++RF+L++EG D L+L G AG SQ N+++GP++ + G YRC
Sbjct: 240 ESLTLQCVSDVSYDRFVLYKEG-ERDFLQLPGPQPQAGLSQANFTLGPVSRSYGGQYRCS 298
Query: 197 GSVTHLPYELSAPSDPLDIVVVGLY-GKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHL 255
G+ +L E SAPSDPLDI++ G + G+P +S PGPTV +GENVTL C S F + L
Sbjct: 299 GAY-NLSSEWSAPSDPLDILIAGQFRGRPFISVHPGPTVASGENVTLLCQSWGPFHTFLL 357
Query: 256 SREAEA-GELRLTAVLRVNGTFQANFPLGPVT--HGGNYRCFGSFRALPHAWSDPSDPLP 312
++ A LRL ++ +QA FP+ PVT H G YRC+GS + P+ S PSD L
Sbjct: 358 TKAGAADAPLRLRSI-HEYPKYQAEFPMSPVTSAHSGTYRCYGSLSSNPYLLSHPSDSLE 416
Query: 313 VSVTGNSRHL 322
+ V+G + L
Sbjct: 417 LMVSGAAETL 426
Score = 203 bits (517), Expect = 2e-52
Identities = 131/331 (39%), Positives = 185/331 (55%), Gaps = 19/331 (5%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHV--GGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEF 58
M+ +V + C+ L GP HV G KP L A PG+V+++G VTL C+ L E+
Sbjct: 1 MTPIVTVLICLRLSL--GPRTHVQAGTLPKPTLWAEPGSVITQGSPVTLWCQGILETQEY 58
Query: 59 SLSKEDGMP-----VPELYNRIFRNSFLMGPVTPAHAGTYRCC-SSHPHSPTGWSAPSNP 112
L +E +P+ + + F + +T H G YRC SH GWS PS+P
Sbjct: 59 RLYREKKTAPWITRIPQ--EIVKKGQFPIPSITWEHTGRYRCFYGSHT---AGWSEPSDP 113
Query: 113 VVIMVTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLH 172
+ ++VTG + KP+L A P P+V SG V L C S V F F+L +EG E P L Q
Sbjct: 114 LELVVTGAYIKPTLSALPSPVVTSGGNVTLHCVSQVAFGSFILCKEGEDEHPQCLNSQPR 173
Query: 173 DAG-SQVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPG 231
G S+ +S+GP++P+ +YRC+ ++ P+ S PSD L+++V+G+ KPSLS QPG
Sbjct: 174 THGWSRAIFSVGPVSPSRRWSYRCYAYDSNSPHVWSLPSDLLELLVLGVSKKPSLSVQPG 233
Query: 232 PTVQAGENVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPV--THGG 289
P V GE++TL C S +D + L +E E L+L G QANF LGPV ++GG
Sbjct: 234 PIVAPGESLTLQCVSDVSYDRFVLYKEGERDFLQLPGPQPQAGLSQANFTLGPVSRSYGG 293
Query: 290 NYRCFGSFRALPHAWSDPSDPLPVSVTGNSR 320
YRC G++ L WS PSDPL + + G R
Sbjct: 294 QYRCSGAYN-LSSEWSAPSDPLDILIAGQFR 323
Score = 144 bits (362), Expect = 2e-34
Identities = 82/203 (40%), Positives = 119/203 (58%), Gaps = 7/203 (3%)
Query: 23 VGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKEDG-----MPVPELYNRIFR 77
+G KP LS PG +V+ G+ +TLQC S + ++ F L KE +P P+ + +
Sbjct: 220 LGVSKKPSLSVQPGPIVAPGESLTLQCVSDVSYDRFVLYKEGERDFLQLPGPQPQAGLSQ 279
Query: 78 NSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGVHR-KPSLLAHPGPLVKS 136
+F +GPV+ ++ G YRC ++ S + WSAPS+P+ I++ G R +P + HPGP V S
Sbjct: 280 ANFTLGPVSRSYGGQYRCSGAYNLS-SEWSAPSDPLDILIAGQFRGRPFISVHPGPTVAS 338
Query: 137 GETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNYSMGPMTPALAGTYRCF 196
GE V L C S F FLL + G + PLRL Q + M P+T A +GTYRC+
Sbjct: 339 GENVTLLCQSWGPFHTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHSGTYRCY 398
Query: 197 GSVTHLPYELSAPSDPLDIVVVG 219
GS++ PY LS PSD L+++V G
Sbjct: 399 GSLSSNPYLLSHPSDSLELMVSG 421
Score = 109 bits (272), Expect = 5e-24
Identities = 77/220 (35%), Positives = 112/220 (50%), Gaps = 9/220 (4%)
Query: 119 GVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQV 178
G KP+L A PG ++ G V L C + + + L+RE T + + Q + +
Sbjct: 24 GTLPKPTLWAEPGSVITQGSPVTLWCQGILETQEYRLYREKKTAPWITRIPQ--EIVKKG 81
Query: 179 NYSMGPMTPALAGTYRCF-GSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAG 237
+ + +T G YRCF GS T S PSDPL++VV G Y KP+LSA P P V +G
Sbjct: 82 QFPIPSITWEHTGRYRCFYGSHTA---GWSEPSDPLELVVTGAYIKPTLSALPSPVVTSG 138
Query: 238 ENVTLSCSSRSLFDIYHLSREAEAGELR-LTAVLRVNGTFQANFPLGPVTHGG--NYRCF 294
NVTL C S+ F + L +E E + L + R +G +A F +GPV+ +YRC+
Sbjct: 139 GNVTLHCVSQVAFGSFILCKEGEDEHPQCLNSQPRTHGWSRAIFSVGPVSPSRRWSYRCY 198
Query: 295 GSFRALPHAWSDPSDPLPVSVTGNSRHLHVLIGTSVVIIP 334
PH WS PSD L + V G S+ + + ++ P
Sbjct: 199 AYDSNSPHVWSLPSDLLELLVLGVSKKPSLSVQPGPIVAP 238
>gi|47519953 leukocyte immunoglobulin-like receptor subfamily A
member 4 [Homo sapiens]
Length = 499
Score = 219 bits (557), Expect = 5e-57
Identities = 130/311 (41%), Positives = 186/311 (59%), Gaps = 12/311 (3%)
Query: 23 VGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKEDGMPVPELYNRI------F 76
V +P LSA P VV+ G +VTL+C SRLG F+L +E + N F
Sbjct: 117 VTAYSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKF 176
Query: 77 RNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGVHRKPSLLAHPGPLVKS 136
+ F MGP+T ++ GT+RC ++P WS PS+P+ ++V+GV RKPSLL GP+V
Sbjct: 177 QALFPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTP 236
Query: 137 GETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNYSMGPMTPALAGTYRCF 196
GE + LQC SDV + R+ L++EG P R Q SQ N+++ P++ + G YRC+
Sbjct: 237 GENLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCY 296
Query: 197 GSVTHLPYELSAPSDPLDIVVVG-LYGKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHL 255
G+ ++ E SAPSDPLDI++ G + +PSLS QPGPTV +GE VTL C S + L
Sbjct: 297 GA-HNVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLL 355
Query: 256 SREAEA-GELRLTAVLRVNGTFQANFPLGPVT--HGGNYRCFGSFRALPHAWSDPSDPLP 312
++E A LRL ++ + +QA FP+ PVT H G YRC+GS + P+ S PS+PL
Sbjct: 356 TKEGAAHPPLRLRSMYGAH-KYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLE 414
Query: 313 VSVTGNSRHLH 323
+ V+G + L+
Sbjct: 415 LVVSGATETLN 425
Score = 171 bits (434), Expect = 8e-43
Identities = 118/325 (36%), Positives = 164/325 (50%), Gaps = 15/325 (4%)
Query: 1 MSLMVVSMACVGFFLLEGPWPHVGGQD--KPFLSAWPGTVVSEGQHVTLQCRSRLGFNEF 58
M+L++ S+ G L GP V ++ KP L A PG V++ VT+ C+ L +
Sbjct: 1 MTLILTSLLFFGLSL--GPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGY 58
Query: 59 SLSKEDGMPVPELYNRIFRNSFLMGPVTPA---HAGTYRCCSSHPHSPTGWSAPSNPVVI 115
L KE + + + + + HAG Y C + SP GWS PS+P+ +
Sbjct: 59 RLDKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHC---YYQSPAGWSEPSDPLEL 115
Query: 116 MVTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAG 175
+VT R P+L A P P+V SG V L+C S + RF L EG L H+ G
Sbjct: 116 VVTAYSR-PTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHG 174
Query: 176 S-QVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTV 234
Q + MGP+T + GT+RC+G + PY S PSDPL ++V G+ KPSL GP V
Sbjct: 175 KFQALFPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVV 234
Query: 235 QAGENVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPV--THGGNYR 292
GEN+TL C S + Y L +E G + G QANF L PV ++GG YR
Sbjct: 235 TPGENLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYR 294
Query: 293 CFGSFRALPHAWSDPSDPLPVSVTG 317
C+G+ + WS PSDPL + + G
Sbjct: 295 CYGAHN-VSSEWSAPSDPLDILIAG 318
Score = 116 bits (290), Expect = 4e-26
Identities = 79/218 (36%), Positives = 115/218 (52%), Gaps = 15/218 (6%)
Query: 123 KPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNYSM 182
KP L A PGP++ V + C + + + L +EG + R + + ++ ++V S+
Sbjct: 28 KPILWAEPGPVITWHNPVTIWCQGTLEAQGYRLDKEGNSMS--RHILKTLESENKVKLSI 85
Query: 183 GPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGENVTL 242
M AG Y C+ P S PSDPL++VV Y +P+LSA P P V +G NVTL
Sbjct: 86 PSMMWEHAGRYHCY---YQSPAGWSEPSDPLELVVTA-YSRPTLSALPSPVVTSGVNVTL 141
Query: 243 SCSSRSLFDIYHLSREAEAGELRLTAVLRVN----GTFQANFPLGPVTHG--GNYRCFGS 296
C+SR + L E G+ RL+ L + G FQA FP+GP+T G +RC+G
Sbjct: 142 RCASRLGLGRFTLIEE---GDHRLSWTLNSHQHNHGKFQALFPMGPLTFSNRGTFRCYGY 198
Query: 297 FRALPHAWSDPSDPLPVSVTGNSRHLHVLIGTSVVIIP 334
P+ WS+PSDPL + V+G SR +L V+ P
Sbjct: 199 ENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTP 236
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.432
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,595,877
Number of Sequences: 37866
Number of extensions: 953857
Number of successful extensions: 3505
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 80
Number of HSP's successfully gapped in prelim test: 58
Number of HSP's that attempted gapping in prelim test: 2497
Number of HSP's gapped (non-prelim): 369
length of query: 410
length of database: 18,247,518
effective HSP length: 105
effective length of query: 305
effective length of database: 14,271,588
effective search space: 4352834340
effective search space used: 4352834340
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.