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Search of human proteins with 4557427
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4557427 ectonucleoside triphosphate diphosphohydrolase 5
[Homo sapiens]
(428 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4557427 ectonucleoside triphosphate diphosphohydrolase 5 [Hom... 871 0.0
gi|166235895 ectonucleoside triphosphate diphosphohydrolase 6 is... 385 e-107
gi|166235893 ectonucleoside triphosphate diphosphohydrolase 6 is... 385 e-107
gi|110431368 ectonucleoside triphosphate diphosphohydrolase 8 is... 124 2e-28
gi|193083168 ectonucleoside triphosphate diphosphohydrolase 4 is... 120 3e-27
gi|166197702 ectonucleoside triphosphate diphosphohydrolase 3 [H... 119 4e-27
gi|147905700 ectonucleoside triphosphate diphosphohydrolase 1 is... 118 9e-27
gi|45580700 ectonucleoside triphosphate diphosphohydrolase 1 iso... 118 9e-27
gi|4758662 ectonucleoside triphosphate diphosphohydrolase 4 isof... 118 1e-26
gi|110431366 ectonucleoside triphosphate diphosphohydrolase 8 is... 116 3e-26
gi|9966821 ectonucleoside triphosphate diphosphohydrolase 7 [Hom... 115 8e-26
gi|45827718 ectonucleoside triphosphate diphosphohydrolase 2 iso... 114 2e-25
gi|4557421 ectonucleoside triphosphate diphosphohydrolase 2 isof... 111 1e-24
gi|4759180 serine/threonine kinase 19 isoform 1 [Homo sapiens] 32 1.4
gi|40548372 tetratricopeptide repeat domain 15 [Homo sapiens] 29 7.2
>gi|4557427 ectonucleoside triphosphate diphosphohydrolase 5 [Homo
sapiens]
Length = 428
Score = 871 bits (2250), Expect = 0.0
Identities = 428/428 (100%), Positives = 428/428 (100%)
Query: 1 MATSWGTVFFMLVVSCVCSAVSHRNQQTWFEGIFLSSMCPINVSASTLYGIMFDAGSTGT 60
MATSWGTVFFMLVVSCVCSAVSHRNQQTWFEGIFLSSMCPINVSASTLYGIMFDAGSTGT
Sbjct: 1 MATSWGTVFFMLVVSCVCSAVSHRNQQTWFEGIFLSSMCPINVSASTLYGIMFDAGSTGT 60
Query: 61 RIHVYTFVQKMPGQLPILEGEVFDSVKPGLSAFVDQPKQGAETVQGLLEVAKDSIPRSHW 120
RIHVYTFVQKMPGQLPILEGEVFDSVKPGLSAFVDQPKQGAETVQGLLEVAKDSIPRSHW
Sbjct: 61 RIHVYTFVQKMPGQLPILEGEVFDSVKPGLSAFVDQPKQGAETVQGLLEVAKDSIPRSHW 120
Query: 121 KKTPVVLKATAGLRLLPEHKAKALLFEVKEIFRKSPFLVPKGSVSIMDGSDEGILAWVTV 180
KKTPVVLKATAGLRLLPEHKAKALLFEVKEIFRKSPFLVPKGSVSIMDGSDEGILAWVTV
Sbjct: 121 KKTPVVLKATAGLRLLPEHKAKALLFEVKEIFRKSPFLVPKGSVSIMDGSDEGILAWVTV 180
Query: 181 NFLTGQLHGHRQETVGTLDLGGASTQITFLPQFEKTLEQTPRGYLTSFEMFNSTYKLYTH 240
NFLTGQLHGHRQETVGTLDLGGASTQITFLPQFEKTLEQTPRGYLTSFEMFNSTYKLYTH
Sbjct: 181 NFLTGQLHGHRQETVGTLDLGGASTQITFLPQFEKTLEQTPRGYLTSFEMFNSTYKLYTH 240
Query: 241 SYLGFGLKAARLATLGALETEGTDGHTFRSACLPRWLEAEWIFGGVKYQYGGNQEGEVGF 300
SYLGFGLKAARLATLGALETEGTDGHTFRSACLPRWLEAEWIFGGVKYQYGGNQEGEVGF
Sbjct: 241 SYLGFGLKAARLATLGALETEGTDGHTFRSACLPRWLEAEWIFGGVKYQYGGNQEGEVGF 300
Query: 301 EPCYAEVLRVVRGKLHQPEEVQRGSFYAFSYYYDRAVDTDMIDYEKGGILKVEDFERKAR 360
EPCYAEVLRVVRGKLHQPEEVQRGSFYAFSYYYDRAVDTDMIDYEKGGILKVEDFERKAR
Sbjct: 301 EPCYAEVLRVVRGKLHQPEEVQRGSFYAFSYYYDRAVDTDMIDYEKGGILKVEDFERKAR 360
Query: 361 EVCDNLENFTSGSPFLCMDLSYITALLKDGFGFADSTVLQLTKKVNNIETGWALGATFHL 420
EVCDNLENFTSGSPFLCMDLSYITALLKDGFGFADSTVLQLTKKVNNIETGWALGATFHL
Sbjct: 361 EVCDNLENFTSGSPFLCMDLSYITALLKDGFGFADSTVLQLTKKVNNIETGWALGATFHL 420
Query: 421 LQSLGISH 428
LQSLGISH
Sbjct: 421 LQSLGISH 428
>gi|166235895 ectonucleoside triphosphate diphosphohydrolase 6
isoform 2 [Homo sapiens]
Length = 467
Score = 385 bits (989), Expect = e-107
Identities = 201/377 (53%), Positives = 256/377 (67%), Gaps = 3/377 (0%)
Query: 49 YGIMFDAGSTGTRIHVYTFVQKMPGQLPILEGEVFDSVKPGLSAFVDQPKQGAETVQGLL 108
YGIMFDAGSTGTR+HV+ F + P + P L E F ++KPGLSA+ D ++ A+ ++ LL
Sbjct: 85 YGIMFDAGSTGTRVHVFQFTRP-PRETPTLTHETFKALKPGLSAYADDVEKSAQGIRELL 143
Query: 109 EVAKDSIPRSHWKKTPVVLKATAGLRLLPEHKAKALLFEVKEIFRKSPFLVPKGSVSIMD 168
+VAK IP WK TP+VLKATAGLRLLP KA+ LL +VKE+F+ SPFLV VSIM+
Sbjct: 144 DVAKQDIPFDFWKATPLVLKATAGLRLLPGEKAQKLLQKVKEVFKASPFLVGDDCVSIMN 203
Query: 169 GSDEGILAWVTVNFLTGQLHGHRQETVGTLDLGGASTQITFLPQFEKTLEQTPRGYLTSF 228
G+DEG+ AW+T+NFLTG L +VG LDLGG STQI FLP+ E TL+ +P GYLT+
Sbjct: 204 GTDEGVSAWITINFLTGSLKTPGGSSVGMLDLGGGSTQIAFLPRVEGTLQASPPGYLTAL 263
Query: 229 EMFNSTYKLYTHSYLGFGLKAARLATLGALETE-GTDGHTFRSACLPRWLEAEWIFGGVK 287
MFN TYKLY++SYLG GL +ARLA LG +E + DG S CL + EW V
Sbjct: 264 RMFNRTYKLYSYSYLGLGLMSARLAILGGVEGQPAKDGKELVSPCLSPSFKGEWEHAEVT 323
Query: 288 YQYGGNQEGEVGFEPCYAEVLRVVRGKLHQPEEVQRGSFYAFSYYYDRAVDTDMIDYEKG 347
Y+ G + E C A V V++ ++H+ EEV+ FYAFSYYYD A +ID EKG
Sbjct: 324 YRVSGQKAAASLHELCAARVSEVLQNRVHRTEEVKHVDFYAFSYYYDLAAGVGLIDAEKG 383
Query: 348 GILKVEDFERKAREVCDNLENFTSGSPFLCMDLSYITALLKDGFGFADSTVLQLTKKVNN 407
G L V DFE A+ VC LE SPF CMDL+Y++ LL++ FGF S VL+LT+K++N
Sbjct: 384 GSLVVGDFEIAAKYVCRTLETQPQSSPFSCMDLTYVSLLLQE-FGFPRSKVLKLTRKIDN 442
Query: 408 IETGWALGATFHLLQSL 424
+ET WALGA FH + SL
Sbjct: 443 VETSWALGAIFHYIDSL 459
>gi|166235893 ectonucleoside triphosphate diphosphohydrolase 6
isoform 1 [Homo sapiens]
Length = 484
Score = 385 bits (989), Expect = e-107
Identities = 201/377 (53%), Positives = 256/377 (67%), Gaps = 3/377 (0%)
Query: 49 YGIMFDAGSTGTRIHVYTFVQKMPGQLPILEGEVFDSVKPGLSAFVDQPKQGAETVQGLL 108
YGIMFDAGSTGTR+HV+ F + P + P L E F ++KPGLSA+ D ++ A+ ++ LL
Sbjct: 102 YGIMFDAGSTGTRVHVFQFTRP-PRETPTLTHETFKALKPGLSAYADDVEKSAQGIRELL 160
Query: 109 EVAKDSIPRSHWKKTPVVLKATAGLRLLPEHKAKALLFEVKEIFRKSPFLVPKGSVSIMD 168
+VAK IP WK TP+VLKATAGLRLLP KA+ LL +VKE+F+ SPFLV VSIM+
Sbjct: 161 DVAKQDIPFDFWKATPLVLKATAGLRLLPGEKAQKLLQKVKEVFKASPFLVGDDCVSIMN 220
Query: 169 GSDEGILAWVTVNFLTGQLHGHRQETVGTLDLGGASTQITFLPQFEKTLEQTPRGYLTSF 228
G+DEG+ AW+T+NFLTG L +VG LDLGG STQI FLP+ E TL+ +P GYLT+
Sbjct: 221 GTDEGVSAWITINFLTGSLKTPGGSSVGMLDLGGGSTQIAFLPRVEGTLQASPPGYLTAL 280
Query: 229 EMFNSTYKLYTHSYLGFGLKAARLATLGALETE-GTDGHTFRSACLPRWLEAEWIFGGVK 287
MFN TYKLY++SYLG GL +ARLA LG +E + DG S CL + EW V
Sbjct: 281 RMFNRTYKLYSYSYLGLGLMSARLAILGGVEGQPAKDGKELVSPCLSPSFKGEWEHAEVT 340
Query: 288 YQYGGNQEGEVGFEPCYAEVLRVVRGKLHQPEEVQRGSFYAFSYYYDRAVDTDMIDYEKG 347
Y+ G + E C A V V++ ++H+ EEV+ FYAFSYYYD A +ID EKG
Sbjct: 341 YRVSGQKAAASLHELCAARVSEVLQNRVHRTEEVKHVDFYAFSYYYDLAAGVGLIDAEKG 400
Query: 348 GILKVEDFERKAREVCDNLENFTSGSPFLCMDLSYITALLKDGFGFADSTVLQLTKKVNN 407
G L V DFE A+ VC LE SPF CMDL+Y++ LL++ FGF S VL+LT+K++N
Sbjct: 401 GSLVVGDFEIAAKYVCRTLETQPQSSPFSCMDLTYVSLLLQE-FGFPRSKVLKLTRKIDN 459
Query: 408 IETGWALGATFHLLQSL 424
+ET WALGA FH + SL
Sbjct: 460 VETSWALGAIFHYIDSL 476
>gi|110431368 ectonucleoside triphosphate diphosphohydrolase 8
isoform 1 [Homo sapiens]
Length = 495
Score = 124 bits (311), Expect = 2e-28
Identities = 118/417 (28%), Positives = 179/417 (42%), Gaps = 56/417 (13%)
Query: 49 YGIMFDAGSTGTRIHVYTFVQKMPGQLPILEGEVFDSVK-PGLSAFVDQPKQGAETVQGL 107
+GI+FDAGS+ T + +Y ++ ++ + V+ PG+S++ Q E++QG
Sbjct: 43 FGIVFDAGSSHTSLFLYQWLANKENGTGVVSQALACQVEGPGISSYTSNAAQAGESLQGC 102
Query: 108 LEVAKDSIPRSHWKKTPVVLKATAGLRLLP---EHKAKALLFEVKEIFRKSPFLVPKGSV 164
LE A IP + +KTP L ATAG+RLL +A+ + V ++ +SP V
Sbjct: 103 LEEALVLIPEAQHRKTPTFLGATAGMRLLSRKNSSQARDIFAAVTQVLGRSP--VDFWGA 160
Query: 165 SIMDGSDEGILAWVTVNFLTGQLHGH----------RQETVGTLDLGGASTQITFLPQFE 214
++ G EG W+TVN+ G L + + VG LD+GGASTQITF+P
Sbjct: 161 ELLAGQAEGAFGWITVNYGLGTLVKYSFTGEWIQPPEEMLVGALDMGGASTQITFVPGGP 220
Query: 215 KTLEQTPRGYLTSFEMFNSTYKLYTHSYLGF-----------GLKAARLAT-------LG 256
+ T F ++ S Y +YTHSYL F GL +R A L
Sbjct: 221 ILDKSTQ----ADFRLYGSDYSVYTHSYLCFGRDQMLSRLLVGLVQSRPAALLRHPCYLS 276
Query: 257 ALETEGTDGHTFRSAC--------LPRWLEAEWIFGGVKYQYGGNQEGEVGFEPCYAEVL 308
+T G + S C LP+ L E G +E F C +
Sbjct: 277 GYQTTLALGPLYESPCVHATPPLSLPQNLTVEGT-GNPGACVSAIRE-LFNFSSCQGQED 334
Query: 309 RVVRGKLHQPEEVQRGSFYAFSYYYDRAVDTDMIDYEKGGILKVEDFERKAREVCDNLEN 368
G P RG FYAFS +Y ++ + + +E R +
Sbjct: 335 CAFDGVYQPP---LRGQFYAFSNFYYTFHFLNLTSRQPLSTVNATIWEFCQRPWKLVEAS 391
Query: 369 FTSGSPFL---CMDLSYITALLKDGFGFADST--VLQLTKKVNNIETGWALGATFHL 420
+ +L C YI LL +G+GF++ T L+ K+ ++ GW LG +L
Sbjct: 392 YPGQDRWLRDYCASGLYILTLLHEGYGFSEETWPSLEFRKQAGGVDIGWTLGYMLNL 448
>gi|193083168 ectonucleoside triphosphate diphosphohydrolase 4
isoform b [Homo sapiens]
Length = 608
Score = 120 bits (300), Expect = 3e-27
Identities = 111/444 (25%), Positives = 179/444 (40%), Gaps = 80/444 (18%)
Query: 49 YGIMFDAGSTGTRIHVYTFVQKMPGQLPILE---------GEVFDSVKPGLSAFVDQPKQ 99
YGI+ D GS+G+R+ VY + + +L+ V +KPG+S F P++
Sbjct: 89 YGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDIRQMRDKNRKPVVMKIKPGISEFATSPEK 148
Query: 100 GAETVQGLLEVAKDSIPRSHWKKTPVVLKATAGLRLLPEHKAKALLFE-VKEIFRKSPFL 158
++ + LL A + +PR+ K+TP+ + TAG+R+LPE + KA+L + + +I FL
Sbjct: 149 VSDYISPLLNFAAEHVPRAKHKETPLYILCTAGMRILPESQQKAILEDLLTDIPVHFDFL 208
Query: 159 VPKGSVSIMDGSDEGILAWVTVNFLTGQLHG----------------------HRQETVG 196
++ G EG+ AW+ +NF+ G+ R+ T G
Sbjct: 209 FSDSHAEVISGKQEGVYAWIGINFVLGRFEHIEDDDEAVVEVNIPGSESSEAIVRKRTAG 268
Query: 197 TLDLGGASTQITFLPQFEKTLEQTPRGYLTSFEM------FNSTYKLYTHSYLGFGLKAA 250
LD+GG STQI + + KT E+ + L F + Y++Y ++LGFG AA
Sbjct: 269 ILDMGGVSTQIAY--EVPKT-EEVAKNLLAEFNLGCDVHQTEHVYRVYVATFLGFGGNAA 325
Query: 251 RLA-------------TLGALETEGTDGHTFRSACLPRWLEAEWIFGGVKYQYGGNQEGE 297
R L +T T + CLP ++ E G G + +
Sbjct: 326 RQRYEDRIFANTIQKNRLLGKQTGLTPDMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFD 385
Query: 298 VGFEPCYA------EVLRVVRGKLHQPEEVQRGSFYAFSYYYDRAVDTDMIDYEKGGILK 351
+ E E + G P Q FY FS +Y D GG
Sbjct: 386 LCRETIQPFMNKTNETQTSLNGVYQPPIHFQNSEFYGFSEFYYCTEDV----LRMGGDYN 441
Query: 352 VEDFERKAREVCDN-----LENFTSG----------SPFLCMDLSYITALLKDGFGF-AD 395
F + A++ C E F G + C +++ + GF F +
Sbjct: 442 AAKFTKAAKDYCATKWSILRERFDRGLYASHADLHRLKYQCFKSAWMFEVFHRGFSFPVN 501
Query: 396 STVLQLTKKVNNIETGWALGATFH 419
L+ +V + E W LGA +
Sbjct: 502 YKSLKTALQVYDKEVQWTLGAILY 525
>gi|166197702 ectonucleoside triphosphate diphosphohydrolase 3 [Homo
sapiens]
Length = 529
Score = 119 bits (299), Expect = 4e-27
Identities = 111/428 (25%), Positives = 172/428 (40%), Gaps = 65/428 (15%)
Query: 49 YGIMFDAGSTGTRIHVYTFVQKMPGQLPILEGEVFDSVK-PGLSAFVDQPKQGAETVQGL 107
YGI+ DAGS+ T ++VY + + ++ SVK G+S++ + P+ +
Sbjct: 57 YGIVLDAGSSRTTVYVYQWPAEKENNTGVVSQTFKCSVKGSGISSYGNNPQDVPRAFEEC 116
Query: 108 LEVAKDSIPRSHWKKTPVVLKATAGLRLLP---EHKAKALLFEVKEIFRKSPFLVPKGSV 164
++ K +P TP+ L ATAG+RLL E A +L ++ F+ PF
Sbjct: 117 MQKVKGQVPSHLHGSTPIHLGATAGMRLLRLQNETAANEVLESIQSYFKSQPF--DFRGA 174
Query: 165 SIMDGSDEGILAWVTVNFLTGQ----------LHGHRQETVGTLDLGGASTQITFLPQFE 214
I+ G +EG+ W+T N+L G +H H ET G LDLGGASTQI+F+ +
Sbjct: 175 QIISGQEEGVYGWITANYLMGNFLEKNLWHMWVHPHGVETTGALDLGGASTQISFVAGEK 234
Query: 215 KTLEQTPRGYLTSFEMFNSTYKLYTHSYLGFGLKAARLATLGALETEGTDGHTFRSACLP 274
L + + ++ Y LYTHS+ +G A L L + + C P
Sbjct: 235 MDLNTSD---IMQVSLYGYVYTLYTHSFQCYGRNEAEKKFLAMLLQNSPTKNHLTNPCYP 291
Query: 275 RWLEAEWIFGGV----------KYQYGGNQ----EGEVGFEPCYAEVLRVVRGKLHQPEE 320
R + G V Y N EG C +V + K +E
Sbjct: 292 RDYSISFTMGHVFDSLCTVDQRPESYNPNDVITFEGTGDPSLCKEKVASIFDFKACHDQE 351
Query: 321 V----------QRGSFYAFSYYYDRAVDTDMIDYEKGGILKVEDFERKAREVCDNLENFT 370
+G F AF+ +Y A ++ G ++ F C +N+
Sbjct: 352 TCSFDGVYQPKIKGPFVAFAGFYYTASALNL-----SGSFSLDTFNSSTWNFCS--QNW- 403
Query: 371 SGSPFL------------CMDLSYITALLKDGFGFADSTVLQL--TKKVNNIETGWALGA 416
S P L C +YI L +G+ F + T Q+ K+V N W+LG
Sbjct: 404 SQLPLLLPKFDEVYARSYCFSANYIYHLFVNGYKFTEETWPQIHFEKEVGNSSIAWSLGY 463
Query: 417 TFHLLQSL 424
L +
Sbjct: 464 MLSLTNQI 471
>gi|147905700 ectonucleoside triphosphate diphosphohydrolase 1
isoform 2 [Homo sapiens]
Length = 517
Score = 118 bits (296), Expect = 9e-27
Identities = 120/440 (27%), Positives = 188/440 (42%), Gaps = 68/440 (15%)
Query: 32 GIFLSSMCPINVSASTLYGIMFDAGSTGTRIHVYTFVQKMPGQLPILEGEVFDSVK-PGL 90
G+ + P NV YGI+ DAGS+ T +++Y + + ++ VK PG+
Sbjct: 43 GLTQNKALPENVK----YGIVLDAGSSHTSLYIYKWPAEKENDTGVVHQVEECRVKGPGI 98
Query: 91 SAFVDQPKQGAETVQGLLEVAKDSIPRSHWKKTPVVLKATAGLRLL---PEHKAKALLFE 147
S FV + + + +E A++ IPRS ++TPV L ATAG+RLL E A +L
Sbjct: 99 SKFVQKVNEIGIYLTDCMERAREVIPRSQHQETPVYLGATAGMRLLRMESEELADRVLDV 158
Query: 148 VKEIFRKSPFLVPKGSVSIMDGSDEGILAWVTVNFLTGQL------------HGHRQETV 195
V+ PF I+ G +EG W+T+N+L G+ + QET
Sbjct: 159 VERSLSNYPF--DFQGARIITGQEEGAYGWITINYLLGKFSQKTRWFSIVPYETNNQETF 216
Query: 196 GTLDLGGASTQITFLPQFEKTLEQTPRGYLTSFEMFNSTYKLYTHSYLGFGLKAARLATL 255
G LDLGGASTQ+TF+PQ +T+E F ++ Y +YTHS+L +G A L
Sbjct: 217 GALDLGGASTQVTFVPQ-NQTIESPDNA--LQFRLYGKDYNVYTHSFLCYGKDQALWQKL 273
Query: 256 GALETEGTDGHTFRSACL------------------PRWLEAEWIFGGVKYQYGGNQEGE 297
A + + R C + E F + Q GN
Sbjct: 274 -AKDIQVASNEILRDPCFHPGYKKVVNVSDLYKTPCTKRFEMTLPFQQFEIQGIGN---- 328
Query: 298 VGFEPCYAEVLRVVRGKLHQPEEVQ---------RGSFYAFSYYYDRAVDTDMIDYEKGG 348
++ C+ +L + + +G F AFS +Y ++ EK
Sbjct: 329 --YQQCHQSILELFNTSYCPYSQCAFNGIFLPPLQGDFGAFSAFYFVMKFLNLTS-EKVS 385
Query: 349 ILKVEDFERK-AREVCDNLENFTSG--SPFL---CMDLSYITALLKDGFGF-ADS-TVLQ 400
KV + +K + + ++ +G +L C +YI +LL G+ F ADS +
Sbjct: 386 QEKVTEMMKKFCAQPWEEIKTSYAGVKEKYLSEYCFSGTYILSLLLQGYHFTADSWEHIH 445
Query: 401 LTKKVNNIETGWALGATFHL 420
K+ + GW LG +L
Sbjct: 446 FIGKIQGSDAGWTLGYMLNL 465
>gi|45580700 ectonucleoside triphosphate diphosphohydrolase 1
isoform 1 [Homo sapiens]
Length = 510
Score = 118 bits (296), Expect = 9e-27
Identities = 120/440 (27%), Positives = 188/440 (42%), Gaps = 68/440 (15%)
Query: 32 GIFLSSMCPINVSASTLYGIMFDAGSTGTRIHVYTFVQKMPGQLPILEGEVFDSVK-PGL 90
G+ + P NV YGI+ DAGS+ T +++Y + + ++ VK PG+
Sbjct: 36 GLTQNKALPENVK----YGIVLDAGSSHTSLYIYKWPAEKENDTGVVHQVEECRVKGPGI 91
Query: 91 SAFVDQPKQGAETVQGLLEVAKDSIPRSHWKKTPVVLKATAGLRLL---PEHKAKALLFE 147
S FV + + + +E A++ IPRS ++TPV L ATAG+RLL E A +L
Sbjct: 92 SKFVQKVNEIGIYLTDCMERAREVIPRSQHQETPVYLGATAGMRLLRMESEELADRVLDV 151
Query: 148 VKEIFRKSPFLVPKGSVSIMDGSDEGILAWVTVNFLTGQL------------HGHRQETV 195
V+ PF I+ G +EG W+T+N+L G+ + QET
Sbjct: 152 VERSLSNYPF--DFQGARIITGQEEGAYGWITINYLLGKFSQKTRWFSIVPYETNNQETF 209
Query: 196 GTLDLGGASTQITFLPQFEKTLEQTPRGYLTSFEMFNSTYKLYTHSYLGFGLKAARLATL 255
G LDLGGASTQ+TF+PQ +T+E F ++ Y +YTHS+L +G A L
Sbjct: 210 GALDLGGASTQVTFVPQ-NQTIESPDNA--LQFRLYGKDYNVYTHSFLCYGKDQALWQKL 266
Query: 256 GALETEGTDGHTFRSACL------------------PRWLEAEWIFGGVKYQYGGNQEGE 297
A + + R C + E F + Q GN
Sbjct: 267 -AKDIQVASNEILRDPCFHPGYKKVVNVSDLYKTPCTKRFEMTLPFQQFEIQGIGN---- 321
Query: 298 VGFEPCYAEVLRVVRGKLHQPEEVQ---------RGSFYAFSYYYDRAVDTDMIDYEKGG 348
++ C+ +L + + +G F AFS +Y ++ EK
Sbjct: 322 --YQQCHQSILELFNTSYCPYSQCAFNGIFLPPLQGDFGAFSAFYFVMKFLNLTS-EKVS 378
Query: 349 ILKVEDFERK-AREVCDNLENFTSG--SPFL---CMDLSYITALLKDGFGF-ADS-TVLQ 400
KV + +K + + ++ +G +L C +YI +LL G+ F ADS +
Sbjct: 379 QEKVTEMMKKFCAQPWEEIKTSYAGVKEKYLSEYCFSGTYILSLLLQGYHFTADSWEHIH 438
Query: 401 LTKKVNNIETGWALGATFHL 420
K+ + GW LG +L
Sbjct: 439 FIGKIQGSDAGWTLGYMLNL 458
>gi|4758662 ectonucleoside triphosphate diphosphohydrolase 4 isoform
a [Homo sapiens]
Length = 616
Score = 118 bits (295), Expect = 1e-26
Identities = 111/451 (24%), Positives = 180/451 (39%), Gaps = 86/451 (19%)
Query: 49 YGIMFDAGSTGTRIHVYTFVQKMPGQLPILE---------GEVFDSVKPGLSAFVDQPKQ 99
YGI+ D GS+G+R+ VY + + +L+ V +KPG+S F P++
Sbjct: 89 YGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDIRQMRDKNRKPVVMKIKPGISEFATSPEK 148
Query: 100 GAETVQGLLEVAKDSIPRSHWKKTPVVLKATAGLRLLPEHKAKALLFE-VKEIFRKSPFL 158
++ + LL A + +PR+ K+TP+ + TAG+R+LPE + KA+L + + +I FL
Sbjct: 149 VSDYISPLLNFAAEHVPRAKHKETPLYILCTAGMRILPESQQKAILEDLLTDIPVHFDFL 208
Query: 159 VPKGSVSIMDGSDEGILAWVTVNFLTGQLHG----------------------HRQETVG 196
++ G EG+ AW+ +NF+ G+ R+ T G
Sbjct: 209 FSDSHAEVISGKQEGVYAWIGINFVLGRFEHIEDDDEAVVEVNIPGSESSEAIVRKRTAG 268
Query: 197 TLDLGGASTQITFLPQFEKTL-------EQTPRGYLTSFEM------FNSTYKLYTHSYL 243
LD+GG STQI + + KT+ E+ + L F + Y++Y ++L
Sbjct: 269 ILDMGGVSTQIAY--EVPKTVSFASSQQEEVAKNLLAEFNLGCDVHQTEHVYRVYVATFL 326
Query: 244 GFGLKAARLA-------------TLGALETEGTDGHTFRSACLPRWLEAEWIFGGVKYQY 290
GFG AAR L +T T + CLP ++ E G
Sbjct: 327 GFGGNAARQRYEDRIFANTIQKNRLLGKQTGLTPDMPYLDPCLPLDIKDEIQQNGQTIYL 386
Query: 291 GGNQEGEVGFEPCYA------EVLRVVRGKLHQPEEVQRGSFYAFSYYYDRAVDTDMIDY 344
G + ++ E E + G P Q FY FS +Y D
Sbjct: 387 RGTGDFDLCRETIQPFMNKTNETQTSLNGVYQPPIHFQNSEFYGFSEFYYCTEDV----L 442
Query: 345 EKGGILKVEDFERKAREVCDN-----LENFTSG----------SPFLCMDLSYITALLKD 389
GG F + A++ C E F G + C +++ +
Sbjct: 443 RMGGDYNAAKFTKAAKDYCATKWSILRERFDRGLYASHADLHRLKYQCFKSAWMFEVFHR 502
Query: 390 GFGF-ADSTVLQLTKKVNNIETGWALGATFH 419
GF F + L+ +V + E W LGA +
Sbjct: 503 GFSFPVNYKSLKTALQVYDKEVQWTLGAILY 533
>gi|110431366 ectonucleoside triphosphate diphosphohydrolase 8
isoform 2 [Homo sapiens]
Length = 458
Score = 116 bits (291), Expect = 3e-26
Identities = 115/417 (27%), Positives = 170/417 (40%), Gaps = 93/417 (22%)
Query: 49 YGIMFDAGSTGTRIHVYTFVQKMPGQLPILEGEVFDSVK-PGLSAFVDQPKQGAETVQGL 107
+GI+FDAGS+ T + +Y ++ ++ + V+ PG+S++ Q E++QG
Sbjct: 43 FGIVFDAGSSHTSLFLYQWLANKENGTGVVSQALACQVEGPGISSYTSNAAQAGESLQGC 102
Query: 108 LEVAKDSIPRSHWKKTPVVLKATAGLRLLPEH---KAKALLFEVKEIFRKSPFLVPKGSV 164
LE A IP + +KTP L ATAG+RLL +A+ + V ++ +SP V
Sbjct: 103 LEEALVLIPEAQHRKTPTFLGATAGMRLLSRKNSSQARDIFAAVTQVLGRSP--VDFWGA 160
Query: 165 SIMDGSDEGILAWVTVNFLTGQLHGH----------RQETVGTLDLGGASTQITFLPQFE 214
++ G EG W+TVN+ G L + + VG LD+GGASTQITF+P
Sbjct: 161 ELLAGQAEGAFGWITVNYGLGTLVKYSFTGEWIQPPEEMLVGALDMGGASTQITFVPGGP 220
Query: 215 KTLEQTPRGYLTSFEMFNSTYKLYTHSYLGF-----------GLKAARLATL-------G 256
+ T F ++ S Y +YTHSYL F GL +R A L
Sbjct: 221 ILDKSTQ----ADFRLYGSDYSVYTHSYLCFGRDQMLSRLLVGLVQSRPAALLRHPCYLS 276
Query: 257 ALETEGTDGHTFRSACL----PRWLEAEWIFGGVKYQYGGNQEGEVG-------FEPCYA 305
+T G + S C+ P L G GN V F C
Sbjct: 277 GYQTTLALGPLYESPCVHATPPLSLPQNLTVEGT-----GNPGACVSAIRELFNFSSCQG 331
Query: 306 EVLRVVRGKLHQPEEVQRGSFYAFSYYYDRAVDTDMIDYEKGGILKVEDFERKAREVCDN 365
+ G P RG FY + Y + D + DY G+
Sbjct: 332 QEDCAFDGVYQPP---LRGQFYVEASYPGQ--DRWLRDYCASGL---------------- 370
Query: 366 LENFTSGSPFLCMDLSYITALLKDGFGFADST--VLQLTKKVNNIETGWALGATFHL 420
YI LL +G+GF++ T L+ K+ ++ GW LG +L
Sbjct: 371 ----------------YILTLLHEGYGFSEETWPSLEFRKQAGGVDIGWTLGYMLNL 411
>gi|9966821 ectonucleoside triphosphate diphosphohydrolase 7 [Homo
sapiens]
Length = 604
Score = 115 bits (288), Expect = 8e-26
Identities = 114/453 (25%), Positives = 183/453 (40%), Gaps = 98/453 (21%)
Query: 49 YGIMFDAGSTGTRIHVYTFVQKMPGQLPILEGE---------VFDSVKPGLSAFVDQPKQ 99
YG++ D GS+G+RI VY + + +L+ + V +KPG+SA D P+
Sbjct: 84 YGLVVDCGSSGSRIFVYFWPRHNGNPHDLLDIKQMRDRNSQPVVKKIKPGISAMADTPEH 143
Query: 100 GAETVQGLLEVAKDSIPRSHWKKTPVVLKATAGLRLLPEHKAKALLFE-VKEIFRKSPFL 158
++ ++ LL A +P K+TP+ + TAG+RLLPE K A+L + VK++ + FL
Sbjct: 144 ASDYLRPLLSFAAAHVPVKKHKETPLYILCTAGMRLLPERKQLAILADLVKDLPLEFDFL 203
Query: 159 VPKGSVSIMDGSDEGILAWVTVNFLTG--------------QLHGHRQETVGTLDLGGAS 204
+ ++ G EG+ AW+ +NF+ G +L R+ TVG LD+GGAS
Sbjct: 204 FSQSQAEVISGKQEGVYAWIGINFVLGRFDHEDESDAEATQELAAGRRRTVGILDMGGAS 263
Query: 205 TQITF-LPQFEKTL----EQTPRGYLTSFEM------FNSTYKLYTHSYLGFGLKAARLA 253
QI + +P L E+ + L F + Y++Y ++LGFG AR
Sbjct: 264 LQIAYEVPTSTSVLPAKQEEAAKILLAEFNLGCDVQHTEHVYRVYVTTFLGFGGNFARQR 323
Query: 254 -------------TLGALETEGTDGHTFRSACLPRWL---------------EAEWIFGG 285
L +T + + F CLP L +W+ G
Sbjct: 324 YEDLVLNETLNKNRLLGQKTGLSPDNPFLDPCLPVGLTDVVERNSQVLHVRGRGDWVSCG 383
Query: 286 VKYQYGGNQEGEVGFEPCYAE---VLRVVRGKLHQPEEVQRGSFYAFSYYYDRAVDTDMI 342
P A + G P + FY FS ++ D I
Sbjct: 384 AM------------LSPLLARSNTSQASLNGIYQSPIDFNNSEFYGFSEFFYCTEDVLRI 431
Query: 343 DYEKGGILKVEDFERKAREVCDN-----LENFTSG----------SPFLCMDLSYITALL 387
GG F + A++ C + F +G + C +++ +L
Sbjct: 432 ----GGRYHGPTFAKAAQDYCGMAWSVLTQRFKNGLFSSHADEHRLKYQCFKSAWMYQVL 487
Query: 388 KDGFGFA-DSTVLQLTKKVNNIETGWALGATFH 419
+GF F D L+ + V + E W LGA +
Sbjct: 488 HEGFHFPYDYPNLRTAQLVYDREVQWTLGAILY 520
>gi|45827718 ectonucleoside triphosphate diphosphohydrolase 2
isoform 1 [Homo sapiens]
Length = 495
Score = 114 bits (284), Expect = 2e-25
Identities = 114/424 (26%), Positives = 172/424 (40%), Gaps = 71/424 (16%)
Query: 49 YGIMFDAGSTGTRIHVYTFVQKMPGQLPIL-EGEVFDSVKPGLSAFVDQPKQGAETVQGL 107
YGI+ DAGS+ T + +Y + I+ + D G+S++ D P ++++ G
Sbjct: 40 YGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGC 99
Query: 108 LEVAKDSIPRSHWKKTPVVLKATAGLRLL----PEHKAKALLFEVKEIFRKSPFLVPKGS 163
LE A +P+ TP+ L ATAG+RLL PE + ++L V + PF
Sbjct: 100 LEQALQDVPKERHAGTPLYLGATAGMRLLNLTNPE-ASTSVLMAVTHTLTQYPF--DFRG 156
Query: 164 VSIMDGSDEGILAWVTVNFL---------TGQLHGHRQETVGTLDLGGASTQITFLPQFE 214
I+ G +EG+ WVT N+L G+ R+ T+G +DLGGASTQIT FE
Sbjct: 157 ARILSGQEEGVFGWVTANYLLENFIKYGWVGRWFRPRKGTLGAMDLGGASTQIT----FE 212
Query: 215 KTLEQTPRGYLTSFEMFNSTYKLYTHSYLGFGLKAARLATLGALETEGTDGHTFRSACLP 274
T R ++ Y++YTHS+L +G R L L H F C P
Sbjct: 213 TTSPAEDRASEVQLHLYGQHYRVYTHSFLCYG----RDQVLQRLLASALQTHGFH-PCWP 267
Query: 275 RWLEAEWIFGGV------------------KYQYGGNQE---------GEVGFEPCYAEV 307
R + + G V + G+ + G F C
Sbjct: 268 RGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVSLSGSSDPHLCRDLVSGLFSFSSC--PF 325
Query: 308 LRVVRGKLHQPEEVQRGSFYAFSYYYDRAVDTDMIDYEKG-GILKVEDFERKAREVCD-- 364
R + QP G+F AFS ++ D + G + ++ E A VC+
Sbjct: 326 SRCSFNGVFQPPVA--GNFVAFSAFF---YTVDFLRTSMGLPVATLQQLEAAAVNVCNQT 380
Query: 365 --NLENFTSGS----PFLCMDLSYITALLKDGFGFADSTV--LQLTKKVNNIETGWALGA 416
L+ G C ++ LL G+GF + + KK + GWALG
Sbjct: 381 WAQLQARVPGQRARLADYCAGAMFVQQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGY 440
Query: 417 TFHL 420
+L
Sbjct: 441 MLNL 444
>gi|4557421 ectonucleoside triphosphate diphosphohydrolase 2 isoform
2 [Homo sapiens]
Length = 472
Score = 111 bits (278), Expect = 1e-24
Identities = 111/416 (26%), Positives = 168/416 (40%), Gaps = 78/416 (18%)
Query: 49 YGIMFDAGSTGTRIHVYTFVQKMPGQLPIL-EGEVFDSVKPGLSAFVDQPKQGAETVQGL 107
YGI+ DAGS+ T + +Y + I+ + D G+S++ D P ++++ G
Sbjct: 40 YGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGC 99
Query: 108 LEVAKDSIPRSHWKKTPVVLKATAGLRLL----PEHKAKALLFEVKEIFRKSPFLVPKGS 163
LE A +P+ TP+ L ATAG+RLL PE + ++L V + PF
Sbjct: 100 LEQALQDVPKERHAGTPLYLGATAGMRLLNLTNPE-ASTSVLMAVTHTLTQYPF--DFRG 156
Query: 164 VSIMDGSDEGILAWVTVNFL---------TGQLHGHRQETVGTLDLGGASTQITFLPQFE 214
I+ G +EG+ WVT N+L G+ R+ T+G +DLGGASTQIT FE
Sbjct: 157 ARILSGQEEGVFGWVTANYLLENFIKYGWVGRWFRPRKGTLGAMDLGGASTQIT----FE 212
Query: 215 KTLEQTPRGYLTSFEMFNSTYKLYTHSYLGFGLKAARLATLGALETEGTDGHTFRSACLP 274
T R ++ Y++YTHS+L +G R L L H F C P
Sbjct: 213 TTSPAEDRASEVQLHLYGQHYRVYTHSFLCYG----RDQVLQRLLASALQTHGFH-PCWP 267
Query: 275 RWLEAEWIFGGV------------------KYQYGGNQE---------GEVGFEPCYAEV 307
R + + G V + G+ + G F C
Sbjct: 268 RGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVSLSGSSDPHLCRDLVSGLFSFSSC--PF 325
Query: 308 LRVVRGKLHQPEEVQRGSFYAFSYYYDRAVDTDMIDYEKG-GILKVEDFERKAREVCDNL 366
R + QP G+F AFS ++ D + G + ++ E A VC+
Sbjct: 326 SRCSFNGVFQPPVA--GNFVAFSAFF---YTVDFLRTSMGLPVATLQQLEAAAVNVCNQ- 379
Query: 367 ENFTSGSPFLCMDLSYITALLKDGFGFADSTV--LQLTKKVNNIETGWALGATFHL 420
++ LL G+GF + + KK + GWALG +L
Sbjct: 380 --------------TWAQQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLNL 421
>gi|4759180 serine/threonine kinase 19 isoform 1 [Homo sapiens]
Length = 364
Score = 31.6 bits (70), Expect = 1.4
Identities = 18/65 (27%), Positives = 29/65 (44%), Gaps = 6/65 (9%)
Query: 343 DYEKGGILKVEDFERKAREVCDN------LENFTSGSPFLCMDLSYITALLKDGFGFADS 396
D + GI+ ED+ + + CD ++ F + C DLS+ + FGF DS
Sbjct: 206 DLDAHGIIFTEDYRTRVLKACDGRPYAGAVQKFLASVLPACGDLSFQQDQMTQTFGFRDS 265
Query: 397 TVLQL 401
+ L
Sbjct: 266 EITHL 270
>gi|40548372 tetratricopeptide repeat domain 15 [Homo sapiens]
Length = 735
Score = 29.3 bits (64), Expect = 7.2
Identities = 20/64 (31%), Positives = 27/64 (42%), Gaps = 5/64 (7%)
Query: 210 LPQFEKTLEQTPRGYLTSFEMFNSTYKLYTHSYLGFGLKAARLATLGALETEGTDGHTFR 269
L Q E ++Q PR YL +FN T S K A L + G +G +F
Sbjct: 674 LRQLEAMVQQDPRHYLHESVLFNLTTMYELESSRSMQKKQALLEAVA-----GKEGDSFN 728
Query: 270 SACL 273
+ CL
Sbjct: 729 TQCL 732
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,803,417
Number of Sequences: 37866
Number of extensions: 690209
Number of successful extensions: 1305
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1241
Number of HSP's gapped (non-prelim): 18
length of query: 428
length of database: 18,247,518
effective HSP length: 105
effective length of query: 323
effective length of database: 14,271,588
effective search space: 4609722924
effective search space used: 4609722924
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.