Search of human proteins with 4503349

Search of human proteins with 4503349

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4503349 deoxyribonuclease II, lysosomal precursor [Homo
sapiens]
         (360 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4503349 deoxyribonuclease II, lysosomal precursor [Homo sapiens]   763   0.0  
gi|194473657 deoxyribonuclease II beta isoform 1 precursor [Homo...   236   3e-62
gi|17402882 deoxyribonuclease II beta isoform 2 [Homo sapiens]        108   1e-23
gi|38016937 lemur tyrosine kinase 2 [Homo sapiens]                     29   5.7  
gi|46560555 transmembrane protein 132E [Homo sapiens]                  29   7.5  
gi|32261332 seizure related 6 homolog (mouse)-like precursor [Ho...    28   9.8  
gi|23308499 zinc finger protein 488 [Homo sapiens]                     28   9.8  

>gi|4503349 deoxyribonuclease II, lysosomal precursor [Homo sapiens]
          Length = 360

 Score =  763 bits (1971), Expect = 0.0
 Identities = 360/360 (100%), Positives = 360/360 (100%)

Query: 1   MIPLLLAALLCVPAGALTCYGDSGQPVDWFVVYKLPALRGSGEAAQRGLQYKYLDESSGG 60
           MIPLLLAALLCVPAGALTCYGDSGQPVDWFVVYKLPALRGSGEAAQRGLQYKYLDESSGG
Sbjct: 1   MIPLLLAALLCVPAGALTCYGDSGQPVDWFVVYKLPALRGSGEAAQRGLQYKYLDESSGG 60

Query: 61  WRDGRALINSPEGAVGRSLQPLYRSNTSQLAFLLYNDQPPQPSKAQDSSMRGHTKGVLLL 120
           WRDGRALINSPEGAVGRSLQPLYRSNTSQLAFLLYNDQPPQPSKAQDSSMRGHTKGVLLL
Sbjct: 61  WRDGRALINSPEGAVGRSLQPLYRSNTSQLAFLLYNDQPPQPSKAQDSSMRGHTKGVLLL 120

Query: 121 DHDGGFWLVHSVPNFPPPASSAAYSWPHSACTYGQTLLCVSFPFAQFSKMGKQLTYTYPW 180
           DHDGGFWLVHSVPNFPPPASSAAYSWPHSACTYGQTLLCVSFPFAQFSKMGKQLTYTYPW
Sbjct: 121 DHDGGFWLVHSVPNFPPPASSAAYSWPHSACTYGQTLLCVSFPFAQFSKMGKQLTYTYPW 180

Query: 181 VYNYQLEGIFAQEFPDLENVVKGHHVSQEPWNSSITLTSQAGAVFQSFAKFSKFGDDLYS 240
           VYNYQLEGIFAQEFPDLENVVKGHHVSQEPWNSSITLTSQAGAVFQSFAKFSKFGDDLYS
Sbjct: 181 VYNYQLEGIFAQEFPDLENVVKGHHVSQEPWNSSITLTSQAGAVFQSFAKFSKFGDDLYS 240

Query: 241 GWLAAALGTNLQVQFWHKTVGILPSNCSDIWQVLNVNQIAFPGPAGPSFNSTEDHSKWCV 300
           GWLAAALGTNLQVQFWHKTVGILPSNCSDIWQVLNVNQIAFPGPAGPSFNSTEDHSKWCV
Sbjct: 241 GWLAAALGTNLQVQFWHKTVGILPSNCSDIWQVLNVNQIAFPGPAGPSFNSTEDHSKWCV 300

Query: 301 SPKGPWTCVGDMNRNQGEEQRGGGTLCAQLPALWKAFQPLVKNYQPCNGMARKPSRAYKI 360
           SPKGPWTCVGDMNRNQGEEQRGGGTLCAQLPALWKAFQPLVKNYQPCNGMARKPSRAYKI
Sbjct: 301 SPKGPWTCVGDMNRNQGEEQRGGGTLCAQLPALWKAFQPLVKNYQPCNGMARKPSRAYKI 360


>gi|194473657 deoxyribonuclease II beta isoform 1 precursor [Homo
           sapiens]
          Length = 361

 Score =  236 bits (601), Expect = 3e-62
 Identities = 129/350 (36%), Positives = 190/350 (54%), Gaps = 12/350 (3%)

Query: 4   LLLAALLCVPAGALTCYGDSGQPVDWFVVYKLPALRGSGEAAQRGLQYKYLDESSGGWRD 63
           L L     + A  ++C  + G+ VDWF  YKLP  R + E+ + GL+Y YLD ++  WR 
Sbjct: 17  LFLGLFGVLGAATISCRNEEGKAVDWFTFYKLPK-RQNKESGETGLEYLYLDSTTRSWRK 75

Query: 64  GRALINSPEGAVGRSLQPLYR---SNTSQLAFLLYNDQPPQPSKAQDSSMRGHTKGVLLL 120
              L+N  +  +GR+LQ LY    S ++  A+L+YND  P+P     S   GHTKG+LL 
Sbjct: 76  SEQLMNDTKSVLGRTLQQLYEAYASKSNNTAYLIYNDGVPKP--VNYSRKYGHTKGLLLW 133

Query: 121 DHDGGFWLVHSVPNFPPPASSAAYSWPHSACTYGQTLLCVSFPFAQFSKMGKQLTYTYPW 180
           +   GFWL+HS+P FPP      Y +P +    GQ+ +C++F + Q+  +  QL    P 
Sbjct: 134 NRVQGFWLIHSIPQFPP-IPEEGYDYPPTGRRNGQSGICITFKYNQYEAIDSQLLVCNPN 192

Query: 181 VYNYQLEGIFAQEFPDLENVVKGHHVSQEPWNSSITLTSQAGAVFQSFAKFSKFGDDLYS 240
           VY+  +   F QE   +  +      S+ P     TL S  G  F  FAK   F DD+++
Sbjct: 193 VYSCSIPATFHQELIHMPQLCTRASSSEIPGRLLTTLQSAQGQKFLHFAKSDSFLDDIFA 252

Query: 241 GWLAAALGTNLQVQFWHKTVGILPSNCSDIWQVLNVNQIAFPGPAGPSFNSTEDHSKWCV 300
            W+A  L T+L  + W +    LPSNCS  + V N+  I     +   F+S +DH+KWC+
Sbjct: 253 AWMAQRLKTHLLTETWQRKRQELPSNCSLPYHVYNIKAIKLSRHS--YFSSYQDHAKWCI 310

Query: 301 SPKGP---WTCVGDMNRNQGEEQRGGGTLCAQLPALWKAFQPLVKNYQPC 347
           S KG    WTC+GD+NR+  +  R GG +C Q   +++AFQ LV  Y+ C
Sbjct: 311 SQKGTKNRWTCIGDLNRSPHQAFRSGGFICTQNWQIYQAFQGLVLYYESC 360


>gi|17402882 deoxyribonuclease II beta isoform 2 [Homo sapiens]
          Length = 153

 Score =  108 bits (269), Expect = 1e-23
 Identities = 57/144 (39%), Positives = 81/144 (56%), Gaps = 5/144 (3%)

Query: 207 SQEPWNSSITLTSQAGAVFQSFAKFSKFGDDLYSGWLAAALGTNLQVQFWHKTVGILPSN 266
           S+ P     TL S  G  F  FAK   F DD+++ W+A  L T+L  + W +    LPSN
Sbjct: 11  SEIPGRLLTTLQSAQGQKFLHFAKSDSFLDDIFAAWMAQRLKTHLLTETWQRKRQELPSN 70

Query: 267 CSDIWQVLNVNQIAFPGPAGPSFNSTEDHSKWCVSPKGP---WTCVGDMNRNQGEEQRGG 323
           CS  + V N+  I     +   F+S +DH+KWC+S KG    WTC+GD+NR+  +  R G
Sbjct: 71  CSLPYHVYNIKAIKLSRHS--YFSSYQDHAKWCISQKGTKNRWTCIGDLNRSPHQAFRSG 128

Query: 324 GTLCAQLPALWKAFQPLVKNYQPC 347
           G +C Q   +++AFQ LV  Y+ C
Sbjct: 129 GFICTQNWQIYQAFQGLVLYYESC 152


>gi|38016937 lemur tyrosine kinase 2 [Homo sapiens]
          Length = 1503

 Score = 29.3 bits (64), Expect = 5.7
 Identities = 11/15 (73%), Positives = 11/15 (73%)

Query: 136  PPPASSAAYSWPHSA 150
            PPPA S   SWPHSA
Sbjct: 1452 PPPARSTEQSWPHSA 1466


>gi|46560555 transmembrane protein 132E [Homo sapiens]
          Length = 984

 Score = 28.9 bits (63), Expect = 7.5
 Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 1/43 (2%)

Query: 70  SPEGAVGRSLQPL-YRSNTSQLAFLLYNDQPPQPSKAQDSSMR 111
           SP G     + P+ YR + ++LAF L   +PP P+ A  S  R
Sbjct: 33  SPPGPQASPVLPVSYRLSHTRLAFFLREARPPSPAVANSSLQR 75


>gi|32261332 seizure related 6 homolog (mouse)-like precursor [Homo
           sapiens]
          Length = 1024

 Score = 28.5 bits (62), Expect = 9.8
 Identities = 22/84 (26%), Positives = 33/84 (39%), Gaps = 13/84 (15%)

Query: 54  LDESSGGWRDGRALINSPEGA------VGRSLQPLYRSNTSQLAFLLYNDQPPQPSKAQD 107
           ++ S   W     + ++P G       +GR L P Y  NT+   F ++  + P+  K   
Sbjct: 434 INASKPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKL-- 491

Query: 108 SSMRGHTKGVLLLDHDGGFWLVHS 131
                H     LL HD     VHS
Sbjct: 492 -----HLHFERLLLHDKDRMTVHS 510


>gi|23308499 zinc finger protein 488 [Homo sapiens]
          Length = 340

 Score = 28.5 bits (62), Expect = 9.8
 Identities = 10/20 (50%), Positives = 13/20 (65%)

Query: 127 WLVHSVPNFPPPASSAAYSW 146
           WL H+    PPP+SS+  SW
Sbjct: 240 WLEHTQAQVPPPSSSSTTSW 259


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.443 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,323,841
Number of Sequences: 37866
Number of extensions: 834941
Number of successful extensions: 1682
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1669
Number of HSP's gapped (non-prelim): 7
length of query: 360
length of database: 18,247,518
effective HSP length: 103
effective length of query: 257
effective length of database: 14,347,320
effective search space: 3687261240
effective search space used: 3687261240
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.