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Search of human proteins with 4503023
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503023 carnitine O-palmitoyltransferase precursor [Homo
sapiens]
(658 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503023 carnitine O-palmitoyltransferase precursor [Homo sapi... 1332 0.0
gi|21618331 carnitine acetyltransferase precursor [Homo sapiens] 265 1e-70
gi|188595668 choline acetyltransferase isoform 1 [Homo sapiens] 243 5e-64
gi|218931226 choline acetyltransferase isoform 1 [Homo sapiens] 243 5e-64
gi|218931224 choline acetyltransferase isoform 3 [Homo sapiens] 243 5e-64
gi|218931221 choline acetyltransferase isoform 1 [Homo sapiens] 243 5e-64
gi|188595684 choline acetyltransferase isoform 1 [Homo sapiens] 243 5e-64
gi|188595672 choline acetyltransferase isoform 1 [Homo sapiens] 243 5e-64
gi|188595670 choline acetyltransferase isoform 2 [Homo sapiens] 243 5e-64
gi|31542325 peroxisomal carnitine O-octanoyltransferase isoform ... 237 3e-62
gi|223468672 carnitine palmitoyltransferase 1B isoform a [Homo s... 227 2e-59
gi|23238254 carnitine palmitoyltransferase 1B isoform a [Homo sa... 227 2e-59
gi|223468678 carnitine palmitoyltransferase 1B isoform a [Homo s... 227 2e-59
gi|4758050 carnitine palmitoyltransferase 1B isoform a [Homo sap... 227 2e-59
gi|23238256 carnitine palmitoyltransferase 1B isoform a [Homo sa... 227 2e-59
gi|221316602 peroxisomal carnitine O-octanoyltransferase isoform... 222 1e-57
gi|73623030 carnitine palmitoyltransferase 1A liver isoform 1 [H... 207 3e-53
gi|73623028 carnitine palmitoyltransferase 1A liver isoform 2 [H... 205 1e-52
gi|223468670 carnitine palmitoyltransferase 1B isoform c [Homo s... 204 3e-52
gi|22748777 carnitine palmitoyltransferase 1C isoform 2 [Homo sa... 199 7e-51
gi|209862905 carnitine palmitoyltransferase 1C isoform 1 [Homo s... 196 4e-50
gi|223468674 carnitine palmitoyltransferase 1B isoform d [Homo s... 137 2e-32
gi|239749124 PREDICTED: zinc finger protein 716 [Homo sapiens] 33 1.1
gi|122937211 KIAA0368 protein [Homo sapiens] 33 1.1
gi|13787217 FAT tumor suppressor 2 precursor [Homo sapiens] 32 1.4
gi|60498978 elastin microfibril interfacer 2 [Homo sapiens] 32 1.9
gi|145199237 transcription elongation factor B polypeptide 3 bin... 31 3.2
gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo ... 30 5.4
gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po... 30 5.4
gi|6912650 semaphorin 3E [Homo sapiens] 30 5.4
>gi|4503023 carnitine O-palmitoyltransferase precursor [Homo
sapiens]
Length = 658
Score = 1332 bits (3446), Expect = 0.0
Identities = 658/658 (100%), Positives = 658/658 (100%)
Query: 1 MVPRLLLRAWPRGPAVGPGAPSRPLSAGSGPGQYLQRSIVPTMHYQDSLPRLPIPKLEDT 60
MVPRLLLRAWPRGPAVGPGAPSRPLSAGSGPGQYLQRSIVPTMHYQDSLPRLPIPKLEDT
Sbjct: 1 MVPRLLLRAWPRGPAVGPGAPSRPLSAGSGPGQYLQRSIVPTMHYQDSLPRLPIPKLEDT 60
Query: 61 IRRYLSAQKPLLNDGQFRKTEQFCKSFENGIGKELHEQLVALDKQNKHTSYISGPWFDMY 120
IRRYLSAQKPLLNDGQFRKTEQFCKSFENGIGKELHEQLVALDKQNKHTSYISGPWFDMY
Sbjct: 61 IRRYLSAQKPLLNDGQFRKTEQFCKSFENGIGKELHEQLVALDKQNKHTSYISGPWFDMY 120
Query: 121 LSARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNMTVSAIRFLKTLRAGLLEPEVFHLNP 180
LSARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNMTVSAIRFLKTLRAGLLEPEVFHLNP
Sbjct: 121 LSARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNMTVSAIRFLKTLRAGLLEPEVFHLNP 180
Query: 181 AKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNSTRLPKPSRDELFTDDKA 240
AKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNSTRLPKPSRDELFTDDKA
Sbjct: 181 AKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNSTRLPKPSRDELFTDDKA 240
Query: 241 RHLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYILSDSSPAPEFPLAYLTSENRDIWA 300
RHLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYILSDSSPAPEFPLAYLTSENRDIWA
Sbjct: 241 RHLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYILSDSSPAPEFPLAYLTSENRDIWA 300
Query: 301 ELRQKLMSSGNEESLRKVDSAVFCLCLDDFPIKDLVHLSHNMLHGDGTNRWFDKSFNLII 360
ELRQKLMSSGNEESLRKVDSAVFCLCLDDFPIKDLVHLSHNMLHGDGTNRWFDKSFNLII
Sbjct: 301 ELRQKLMSSGNEESLRKVDSAVFCLCLDDFPIKDLVHLSHNMLHGDGTNRWFDKSFNLII 360
Query: 361 AKDGSTAVHFEHSWGDGVAVLRFFNEVFKDSTQTPAVTPQSQPATTDSTVTVQKLNFELT 420
AKDGSTAVHFEHSWGDGVAVLRFFNEVFKDSTQTPAVTPQSQPATTDSTVTVQKLNFELT
Sbjct: 361 AKDGSTAVHFEHSWGDGVAVLRFFNEVFKDSTQTPAVTPQSQPATTDSTVTVQKLNFELT 420
Query: 421 DALKTGITAAKEKFDATMKTLTIDCVQFQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYG 480
DALKTGITAAKEKFDATMKTLTIDCVQFQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYG
Sbjct: 421 DALKTGITAAKEKFDATMKTLTIDCVQFQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYG 480
Query: 481 QTVATYESCSTAAFKHGRTETIRPASVYTKRCSEAFVREPSRHSAGELQQMMVECSKYHG 540
QTVATYESCSTAAFKHGRTETIRPASVYTKRCSEAFVREPSRHSAGELQQMMVECSKYHG
Sbjct: 481 QTVATYESCSTAAFKHGRTETIRPASVYTKRCSEAFVREPSRHSAGELQQMMVECSKYHG 540
Query: 541 QLTKEAAMGQGFDRHLFALRHLAAAKGIILPELYLDPAYGQINHNVLSTSTLSSPAVNLG 600
QLTKEAAMGQGFDRHLFALRHLAAAKGIILPELYLDPAYGQINHNVLSTSTLSSPAVNLG
Sbjct: 541 QLTKEAAMGQGFDRHLFALRHLAAAKGIILPELYLDPAYGQINHNVLSTSTLSSPAVNLG 600
Query: 601 GFAPVVSDGFGVGYAVHDNWIGCNVSSYPGRNAREFLQCVEKALEDMFDALEGKSIKS 658
GFAPVVSDGFGVGYAVHDNWIGCNVSSYPGRNAREFLQCVEKALEDMFDALEGKSIKS
Sbjct: 601 GFAPVVSDGFGVGYAVHDNWIGCNVSSYPGRNAREFLQCVEKALEDMFDALEGKSIKS 658
>gi|21618331 carnitine acetyltransferase precursor [Homo sapiens]
Length = 626
Score = 265 bits (677), Expect = 1e-70
Identities = 194/628 (30%), Positives = 311/628 (49%), Gaps = 69/628 (10%)
Query: 45 YQDSLPRLPIPKLEDTIRRYLSAQKPLLNDGQFRKTEQFCKSFE--NGIGKELHEQLVAL 102
+QD+LPRLP+P L+ ++ YL A +P++++ ++ T+Q F+ G+G+ L + L
Sbjct: 31 HQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLER- 89
Query: 103 DKQNKHTSYISGPWFDM-YLSARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNMTVSAIR 161
+ K +++S W YL R VV+ +P + PK ++ D +R
Sbjct: 90 -RARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVML---PKQDFVD--------LQGQLR 137
Query: 162 FLKTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLF 221
F L G+L+ FK +I + + G PL M+QY+++
Sbjct: 138 FAAKLIEGVLD---------------FKVMIDNETLPVEYLGGK-----PLCMNQYYQIL 177
Query: 222 NSTRLPKPSRDELFTDDKAR----HLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYIL 277
+S R+P P +D + K + H+ V+ F+ DV DG ++ +I L+ I
Sbjct: 178 SSCRVPGPKQDTVSNFSKTKKPPTHITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIW 237
Query: 278 SDSSPAPEFPLAYLTSENRDIWAELRQKLMSSG-NEESLRKVDSAVFCLCLD-DFP-IKD 334
+ S + P+ LTS +R+ WA+ L+ N +S+R + ++F +CLD P + +
Sbjct: 238 NSSLQTNKEPVGILTSNHRNSWAKAYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSE 297
Query: 335 LVHLSH---NMLHGDGT-----NRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNE 386
V+ SH MLHG G+ NRWFDK+ I+A+DGS + +EH+ +G ++ +
Sbjct: 298 DVYRSHVAGQMLHGGGSRLNSGNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDY 357
Query: 387 VFKDSTQTPAVTPQSQPATTDSTVTVQKLNFELTDALKTGITAAKEKFDATMKTLTIDCV 446
V + + + V P +KL F +T +K+ I AK+ ++ L I +
Sbjct: 358 VIEYTKKPELVRSPMVPLPMP-----KKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVM 412
Query: 447 QFQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPAS 506
F GK+F K +KLSPDA Q+A Q+A+ R YGQ ATYES S F GRT+TIR AS
Sbjct: 413 VFHHFGKDFPKSEKLSPDAFIQMALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSAS 472
Query: 507 V----YTKRCSEAFVREPSRHSAGELQQMMVECSKYHGQLTKEAAMGQGFDRHLFALRHL 562
+ + K ++ V E H EL + V+ H T A G+ FDRHL L+
Sbjct: 473 MDSLTFVKAMDDSSVTE---HQKVELLRKAVQA---HRGYTDRAIRGEAFDRHLLGLKLQ 526
Query: 563 AAAKGIILPELYLDPAYGQINHNVLSTSTLSSPAVNLGGFAPVVSDGFGVGYAVHDNWIG 622
A + +P++++D +Y H LSTS + + + F PVV DG+GV Y + I
Sbjct: 527 AIEDLVSMPDIFMDTSYAIAMHFHLSTSQVPAKTDCVMFFGPVVPDGYGVCYNPMEAHIN 586
Query: 623 CNVSSYPG---RNAREFLQCVEKALEDM 647
++S+Y NA +EKAL DM
Sbjct: 587 FSLSAYNSCAETNAARLAHYLEKALLDM 614
>gi|188595668 choline acetyltransferase isoform 1 [Homo sapiens]
Length = 630
Score = 243 bits (619), Expect = 5e-64
Identities = 184/629 (29%), Positives = 305/629 (48%), Gaps = 61/629 (9%)
Query: 46 QDSLPRLPIPKLEDTIRRYLSAQKPLLNDGQFRKTEQFCKSF--ENGIGKELHEQLVALD 103
+ LP+LP+P L+ T+ YL + L+++ QFRK++ + F G+G+ L ++L L+
Sbjct: 10 ESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKL--LE 67
Query: 104 KQNKHTSYISGPWF-DMYLSARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNMTVSAIRF 162
+Q K +++S W DMYL+ R ++ +N +P + F +DQL A ++ + +
Sbjct: 68 RQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASLISGVLSY 127
Query: 163 LKTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFN 222
LL+ + AK ++ PL M QY+ LF+
Sbjct: 128 -----KALLDSHSIPTDCAKGQ----------------------LSGQPLCMKQYYGLFS 160
Query: 223 STRLPKPSRDELFTDDKA-----RHLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYIL 277
S RLP ++D L + + H++V F++ DV+ + S ++ L+ I+
Sbjct: 161 SYRLPGHTQDTLVAQNSSIMPEPEHVIVACCNQFFVLDVVINFRRL-SEGDLFTQLRKIV 219
Query: 278 SDSSPAPEF--PLAYLTSENRDIWAELRQKLMS-SGNEESLRKVDSAVFCLCLDDFPIKD 334
+S E P+ LTS+ R WAE R L+ S N +SL ++ + +CLD +
Sbjct: 220 KMASNEDERLPPIGLLTSDGRSEWAEARTVLVKDSTNRDSLDMIERCICLVCLDAPGGVE 279
Query: 335 L--VHLSHNMLHG-----DGTNRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEV 387
L H + +LHG +G NRW+DKS ++ +DG+ V EHS DG+ +++ +
Sbjct: 280 LSDTHRALQLLHGGGYSKNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHL 339
Query: 388 FKDSTQTPAVTPQSQPATTDSTVTVQKLNFELTDALKTGITAAKEKFDATMKTLTIDCVQ 447
K TQ+ ++ + ++L ++ + ++ + ++ EK +K L +
Sbjct: 340 LKHMTQSSRKLIRAD--SVSELPAPRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYK 397
Query: 448 FQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASV 507
F GK F+KKQK SPDA Q+A Q+AF R + + V TYES S F+ GR + IR A+
Sbjct: 398 FDNYGKTFIKKQKCSPDAFIQVALQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATP 457
Query: 508 YTKRCSEAFVREPSRHS----AGELQQMMVECSKYHGQLTKEAAMGQGFDRHLFALRHLA 563
+ AFVR + H A E ++ + + T A G D HL ALR LA
Sbjct: 458 E----ALAFVRAVTDHKAAVPASEKLLLLKDAIRAQTAYTVMAITGMAIDNHLLALRELA 513
Query: 564 AAKGIILPELYLDPAYGQINHNVLSTSTLSSPAVNLGGFAPVVSDGFGVGYAVHDNWIGC 623
A LPE+++D Y N VLSTS + + + PVV +G+G Y I
Sbjct: 514 RAMCKELPEMFMDETYLMSNRFVLSTSQVPTTTEMFCCYGPVVPNGYGACYNPQPETILF 573
Query: 624 NVSSYPG---RNAREFLQCVEKALEDMFD 649
+SS+ ++ +F + VE++L DM D
Sbjct: 574 CISSFHSCKETSSSKFAKAVEESLIDMRD 602
>gi|218931226 choline acetyltransferase isoform 1 [Homo sapiens]
Length = 630
Score = 243 bits (619), Expect = 5e-64
Identities = 184/629 (29%), Positives = 305/629 (48%), Gaps = 61/629 (9%)
Query: 46 QDSLPRLPIPKLEDTIRRYLSAQKPLLNDGQFRKTEQFCKSF--ENGIGKELHEQLVALD 103
+ LP+LP+P L+ T+ YL + L+++ QFRK++ + F G+G+ L ++L L+
Sbjct: 10 ESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKL--LE 67
Query: 104 KQNKHTSYISGPWF-DMYLSARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNMTVSAIRF 162
+Q K +++S W DMYL+ R ++ +N +P + F +DQL A ++ + +
Sbjct: 68 RQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASLISGVLSY 127
Query: 163 LKTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFN 222
LL+ + AK ++ PL M QY+ LF+
Sbjct: 128 -----KALLDSHSIPTDCAKGQ----------------------LSGQPLCMKQYYGLFS 160
Query: 223 STRLPKPSRDELFTDDKA-----RHLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYIL 277
S RLP ++D L + + H++V F++ DV+ + S ++ L+ I+
Sbjct: 161 SYRLPGHTQDTLVAQNSSIMPEPEHVIVACCNQFFVLDVVINFRRL-SEGDLFTQLRKIV 219
Query: 278 SDSSPAPEF--PLAYLTSENRDIWAELRQKLMS-SGNEESLRKVDSAVFCLCLDDFPIKD 334
+S E P+ LTS+ R WAE R L+ S N +SL ++ + +CLD +
Sbjct: 220 KMASNEDERLPPIGLLTSDGRSEWAEARTVLVKDSTNRDSLDMIERCICLVCLDAPGGVE 279
Query: 335 L--VHLSHNMLHG-----DGTNRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEV 387
L H + +LHG +G NRW+DKS ++ +DG+ V EHS DG+ +++ +
Sbjct: 280 LSDTHRALQLLHGGGYSKNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHL 339
Query: 388 FKDSTQTPAVTPQSQPATTDSTVTVQKLNFELTDALKTGITAAKEKFDATMKTLTIDCVQ 447
K TQ+ ++ + ++L ++ + ++ + ++ EK +K L +
Sbjct: 340 LKHMTQSSRKLIRAD--SVSELPAPRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYK 397
Query: 448 FQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASV 507
F GK F+KKQK SPDA Q+A Q+AF R + + V TYES S F+ GR + IR A+
Sbjct: 398 FDNYGKTFIKKQKCSPDAFIQVALQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATP 457
Query: 508 YTKRCSEAFVREPSRHS----AGELQQMMVECSKYHGQLTKEAAMGQGFDRHLFALRHLA 563
+ AFVR + H A E ++ + + T A G D HL ALR LA
Sbjct: 458 E----ALAFVRAVTDHKAAVPASEKLLLLKDAIRAQTAYTVMAITGMAIDNHLLALRELA 513
Query: 564 AAKGIILPELYLDPAYGQINHNVLSTSTLSSPAVNLGGFAPVVSDGFGVGYAVHDNWIGC 623
A LPE+++D Y N VLSTS + + + PVV +G+G Y I
Sbjct: 514 RAMCKELPEMFMDETYLMSNRFVLSTSQVPTTTEMFCCYGPVVPNGYGACYNPQPETILF 573
Query: 624 NVSSYPG---RNAREFLQCVEKALEDMFD 649
+SS+ ++ +F + VE++L DM D
Sbjct: 574 CISSFHSCKETSSSKFAKAVEESLIDMRD 602
>gi|218931224 choline acetyltransferase isoform 3 [Homo sapiens]
Length = 666
Score = 243 bits (619), Expect = 5e-64
Identities = 184/629 (29%), Positives = 305/629 (48%), Gaps = 61/629 (9%)
Query: 46 QDSLPRLPIPKLEDTIRRYLSAQKPLLNDGQFRKTEQFCKSF--ENGIGKELHEQLVALD 103
+ LP+LP+P L+ T+ YL + L+++ QFRK++ + F G+G+ L ++L L+
Sbjct: 46 ESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKL--LE 103
Query: 104 KQNKHTSYISGPWF-DMYLSARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNMTVSAIRF 162
+Q K +++S W DMYL+ R ++ +N +P + F +DQL A ++ + +
Sbjct: 104 RQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASLISGVLSY 163
Query: 163 LKTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFN 222
LL+ + AK ++ PL M QY+ LF+
Sbjct: 164 -----KALLDSHSIPTDCAKGQ----------------------LSGQPLCMKQYYGLFS 196
Query: 223 STRLPKPSRDELFTDDKA-----RHLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYIL 277
S RLP ++D L + + H++V F++ DV+ + S ++ L+ I+
Sbjct: 197 SYRLPGHTQDTLVAQNSSIMPEPEHVIVACCNQFFVLDVVINFRRL-SEGDLFTQLRKIV 255
Query: 278 SDSSPAPEF--PLAYLTSENRDIWAELRQKLMS-SGNEESLRKVDSAVFCLCLDDFPIKD 334
+S E P+ LTS+ R WAE R L+ S N +SL ++ + +CLD +
Sbjct: 256 KMASNEDERLPPIGLLTSDGRSEWAEARTVLVKDSTNRDSLDMIERCICLVCLDAPGGVE 315
Query: 335 L--VHLSHNMLHG-----DGTNRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEV 387
L H + +LHG +G NRW+DKS ++ +DG+ V EHS DG+ +++ +
Sbjct: 316 LSDTHRALQLLHGGGYSKNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHL 375
Query: 388 FKDSTQTPAVTPQSQPATTDSTVTVQKLNFELTDALKTGITAAKEKFDATMKTLTIDCVQ 447
K TQ+ ++ + ++L ++ + ++ + ++ EK +K L +
Sbjct: 376 LKHMTQSSRKLIRAD--SVSELPAPRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYK 433
Query: 448 FQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASV 507
F GK F+KKQK SPDA Q+A Q+AF R + + V TYES S F+ GR + IR A+
Sbjct: 434 FDNYGKTFIKKQKCSPDAFIQVALQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATP 493
Query: 508 YTKRCSEAFVREPSRHS----AGELQQMMVECSKYHGQLTKEAAMGQGFDRHLFALRHLA 563
+ AFVR + H A E ++ + + T A G D HL ALR LA
Sbjct: 494 E----ALAFVRAVTDHKAAVPASEKLLLLKDAIRAQTAYTVMAITGMAIDNHLLALRELA 549
Query: 564 AAKGIILPELYLDPAYGQINHNVLSTSTLSSPAVNLGGFAPVVSDGFGVGYAVHDNWIGC 623
A LPE+++D Y N VLSTS + + + PVV +G+G Y I
Sbjct: 550 RAMCKELPEMFMDETYLMSNRFVLSTSQVPTTTEMFCCYGPVVPNGYGACYNPQPETILF 609
Query: 624 NVSSYPG---RNAREFLQCVEKALEDMFD 649
+SS+ ++ +F + VE++L DM D
Sbjct: 610 CISSFHSCKETSSSKFAKAVEESLIDMRD 638
>gi|218931221 choline acetyltransferase isoform 1 [Homo sapiens]
Length = 630
Score = 243 bits (619), Expect = 5e-64
Identities = 184/629 (29%), Positives = 305/629 (48%), Gaps = 61/629 (9%)
Query: 46 QDSLPRLPIPKLEDTIRRYLSAQKPLLNDGQFRKTEQFCKSF--ENGIGKELHEQLVALD 103
+ LP+LP+P L+ T+ YL + L+++ QFRK++ + F G+G+ L ++L L+
Sbjct: 10 ESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKL--LE 67
Query: 104 KQNKHTSYISGPWF-DMYLSARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNMTVSAIRF 162
+Q K +++S W DMYL+ R ++ +N +P + F +DQL A ++ + +
Sbjct: 68 RQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASLISGVLSY 127
Query: 163 LKTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFN 222
LL+ + AK ++ PL M QY+ LF+
Sbjct: 128 -----KALLDSHSIPTDCAKGQ----------------------LSGQPLCMKQYYGLFS 160
Query: 223 STRLPKPSRDELFTDDKA-----RHLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYIL 277
S RLP ++D L + + H++V F++ DV+ + S ++ L+ I+
Sbjct: 161 SYRLPGHTQDTLVAQNSSIMPEPEHVIVACCNQFFVLDVVINFRRL-SEGDLFTQLRKIV 219
Query: 278 SDSSPAPEF--PLAYLTSENRDIWAELRQKLMS-SGNEESLRKVDSAVFCLCLDDFPIKD 334
+S E P+ LTS+ R WAE R L+ S N +SL ++ + +CLD +
Sbjct: 220 KMASNEDERLPPIGLLTSDGRSEWAEARTVLVKDSTNRDSLDMIERCICLVCLDAPGGVE 279
Query: 335 L--VHLSHNMLHG-----DGTNRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEV 387
L H + +LHG +G NRW+DKS ++ +DG+ V EHS DG+ +++ +
Sbjct: 280 LSDTHRALQLLHGGGYSKNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHL 339
Query: 388 FKDSTQTPAVTPQSQPATTDSTVTVQKLNFELTDALKTGITAAKEKFDATMKTLTIDCVQ 447
K TQ+ ++ + ++L ++ + ++ + ++ EK +K L +
Sbjct: 340 LKHMTQSSRKLIRAD--SVSELPAPRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYK 397
Query: 448 FQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASV 507
F GK F+KKQK SPDA Q+A Q+AF R + + V TYES S F+ GR + IR A+
Sbjct: 398 FDNYGKTFIKKQKCSPDAFIQVALQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATP 457
Query: 508 YTKRCSEAFVREPSRHS----AGELQQMMVECSKYHGQLTKEAAMGQGFDRHLFALRHLA 563
+ AFVR + H A E ++ + + T A G D HL ALR LA
Sbjct: 458 E----ALAFVRAVTDHKAAVPASEKLLLLKDAIRAQTAYTVMAITGMAIDNHLLALRELA 513
Query: 564 AAKGIILPELYLDPAYGQINHNVLSTSTLSSPAVNLGGFAPVVSDGFGVGYAVHDNWIGC 623
A LPE+++D Y N VLSTS + + + PVV +G+G Y I
Sbjct: 514 RAMCKELPEMFMDETYLMSNRFVLSTSQVPTTTEMFCCYGPVVPNGYGACYNPQPETILF 573
Query: 624 NVSSYPG---RNAREFLQCVEKALEDMFD 649
+SS+ ++ +F + VE++L DM D
Sbjct: 574 CISSFHSCKETSSSKFAKAVEESLIDMRD 602
>gi|188595684 choline acetyltransferase isoform 1 [Homo sapiens]
Length = 630
Score = 243 bits (619), Expect = 5e-64
Identities = 184/629 (29%), Positives = 305/629 (48%), Gaps = 61/629 (9%)
Query: 46 QDSLPRLPIPKLEDTIRRYLSAQKPLLNDGQFRKTEQFCKSF--ENGIGKELHEQLVALD 103
+ LP+LP+P L+ T+ YL + L+++ QFRK++ + F G+G+ L ++L L+
Sbjct: 10 ESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKL--LE 67
Query: 104 KQNKHTSYISGPWF-DMYLSARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNMTVSAIRF 162
+Q K +++S W DMYL+ R ++ +N +P + F +DQL A ++ + +
Sbjct: 68 RQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASLISGVLSY 127
Query: 163 LKTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFN 222
LL+ + AK ++ PL M QY+ LF+
Sbjct: 128 -----KALLDSHSIPTDCAKGQ----------------------LSGQPLCMKQYYGLFS 160
Query: 223 STRLPKPSRDELFTDDKA-----RHLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYIL 277
S RLP ++D L + + H++V F++ DV+ + S ++ L+ I+
Sbjct: 161 SYRLPGHTQDTLVAQNSSIMPEPEHVIVACCNQFFVLDVVINFRRL-SEGDLFTQLRKIV 219
Query: 278 SDSSPAPEF--PLAYLTSENRDIWAELRQKLMS-SGNEESLRKVDSAVFCLCLDDFPIKD 334
+S E P+ LTS+ R WAE R L+ S N +SL ++ + +CLD +
Sbjct: 220 KMASNEDERLPPIGLLTSDGRSEWAEARTVLVKDSTNRDSLDMIERCICLVCLDAPGGVE 279
Query: 335 L--VHLSHNMLHG-----DGTNRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEV 387
L H + +LHG +G NRW+DKS ++ +DG+ V EHS DG+ +++ +
Sbjct: 280 LSDTHRALQLLHGGGYSKNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHL 339
Query: 388 FKDSTQTPAVTPQSQPATTDSTVTVQKLNFELTDALKTGITAAKEKFDATMKTLTIDCVQ 447
K TQ+ ++ + ++L ++ + ++ + ++ EK +K L +
Sbjct: 340 LKHMTQSSRKLIRAD--SVSELPAPRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYK 397
Query: 448 FQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASV 507
F GK F+KKQK SPDA Q+A Q+AF R + + V TYES S F+ GR + IR A+
Sbjct: 398 FDNYGKTFIKKQKCSPDAFIQVALQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATP 457
Query: 508 YTKRCSEAFVREPSRHS----AGELQQMMVECSKYHGQLTKEAAMGQGFDRHLFALRHLA 563
+ AFVR + H A E ++ + + T A G D HL ALR LA
Sbjct: 458 E----ALAFVRAVTDHKAAVPASEKLLLLKDAIRAQTAYTVMAITGMAIDNHLLALRELA 513
Query: 564 AAKGIILPELYLDPAYGQINHNVLSTSTLSSPAVNLGGFAPVVSDGFGVGYAVHDNWIGC 623
A LPE+++D Y N VLSTS + + + PVV +G+G Y I
Sbjct: 514 RAMCKELPEMFMDETYLMSNRFVLSTSQVPTTTEMFCCYGPVVPNGYGACYNPQPETILF 573
Query: 624 NVSSYPG---RNAREFLQCVEKALEDMFD 649
+SS+ ++ +F + VE++L DM D
Sbjct: 574 CISSFHSCKETSSSKFAKAVEESLIDMRD 602
>gi|188595672 choline acetyltransferase isoform 1 [Homo sapiens]
Length = 630
Score = 243 bits (619), Expect = 5e-64
Identities = 184/629 (29%), Positives = 305/629 (48%), Gaps = 61/629 (9%)
Query: 46 QDSLPRLPIPKLEDTIRRYLSAQKPLLNDGQFRKTEQFCKSF--ENGIGKELHEQLVALD 103
+ LP+LP+P L+ T+ YL + L+++ QFRK++ + F G+G+ L ++L L+
Sbjct: 10 ESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKL--LE 67
Query: 104 KQNKHTSYISGPWF-DMYLSARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNMTVSAIRF 162
+Q K +++S W DMYL+ R ++ +N +P + F +DQL A ++ + +
Sbjct: 68 RQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASLISGVLSY 127
Query: 163 LKTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFN 222
LL+ + AK ++ PL M QY+ LF+
Sbjct: 128 -----KALLDSHSIPTDCAKGQ----------------------LSGQPLCMKQYYGLFS 160
Query: 223 STRLPKPSRDELFTDDKA-----RHLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYIL 277
S RLP ++D L + + H++V F++ DV+ + S ++ L+ I+
Sbjct: 161 SYRLPGHTQDTLVAQNSSIMPEPEHVIVACCNQFFVLDVVINFRRL-SEGDLFTQLRKIV 219
Query: 278 SDSSPAPEF--PLAYLTSENRDIWAELRQKLMS-SGNEESLRKVDSAVFCLCLDDFPIKD 334
+S E P+ LTS+ R WAE R L+ S N +SL ++ + +CLD +
Sbjct: 220 KMASNEDERLPPIGLLTSDGRSEWAEARTVLVKDSTNRDSLDMIERCICLVCLDAPGGVE 279
Query: 335 L--VHLSHNMLHG-----DGTNRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEV 387
L H + +LHG +G NRW+DKS ++ +DG+ V EHS DG+ +++ +
Sbjct: 280 LSDTHRALQLLHGGGYSKNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHL 339
Query: 388 FKDSTQTPAVTPQSQPATTDSTVTVQKLNFELTDALKTGITAAKEKFDATMKTLTIDCVQ 447
K TQ+ ++ + ++L ++ + ++ + ++ EK +K L +
Sbjct: 340 LKHMTQSSRKLIRAD--SVSELPAPRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYK 397
Query: 448 FQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASV 507
F GK F+KKQK SPDA Q+A Q+AF R + + V TYES S F+ GR + IR A+
Sbjct: 398 FDNYGKTFIKKQKCSPDAFIQVALQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATP 457
Query: 508 YTKRCSEAFVREPSRHS----AGELQQMMVECSKYHGQLTKEAAMGQGFDRHLFALRHLA 563
+ AFVR + H A E ++ + + T A G D HL ALR LA
Sbjct: 458 E----ALAFVRAVTDHKAAVPASEKLLLLKDAIRAQTAYTVMAITGMAIDNHLLALRELA 513
Query: 564 AAKGIILPELYLDPAYGQINHNVLSTSTLSSPAVNLGGFAPVVSDGFGVGYAVHDNWIGC 623
A LPE+++D Y N VLSTS + + + PVV +G+G Y I
Sbjct: 514 RAMCKELPEMFMDETYLMSNRFVLSTSQVPTTTEMFCCYGPVVPNGYGACYNPQPETILF 573
Query: 624 NVSSYPG---RNAREFLQCVEKALEDMFD 649
+SS+ ++ +F + VE++L DM D
Sbjct: 574 CISSFHSCKETSSSKFAKAVEESLIDMRD 602
>gi|188595670 choline acetyltransferase isoform 2 [Homo sapiens]
Length = 748
Score = 243 bits (619), Expect = 5e-64
Identities = 184/629 (29%), Positives = 305/629 (48%), Gaps = 61/629 (9%)
Query: 46 QDSLPRLPIPKLEDTIRRYLSAQKPLLNDGQFRKTEQFCKSF--ENGIGKELHEQLVALD 103
+ LP+LP+P L+ T+ YL + L+++ QFRK++ + F G+G+ L ++L L+
Sbjct: 128 ESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKL--LE 185
Query: 104 KQNKHTSYISGPWF-DMYLSARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNMTVSAIRF 162
+Q K +++S W DMYL+ R ++ +N +P + F +DQL A ++ + +
Sbjct: 186 RQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASLISGVLSY 245
Query: 163 LKTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFN 222
LL+ + AK ++ PL M QY+ LF+
Sbjct: 246 -----KALLDSHSIPTDCAKGQ----------------------LSGQPLCMKQYYGLFS 278
Query: 223 STRLPKPSRDELFTDDKA-----RHLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYIL 277
S RLP ++D L + + H++V F++ DV+ + S ++ L+ I+
Sbjct: 279 SYRLPGHTQDTLVAQNSSIMPEPEHVIVACCNQFFVLDVVINFRRL-SEGDLFTQLRKIV 337
Query: 278 SDSSPAPEF--PLAYLTSENRDIWAELRQKLMS-SGNEESLRKVDSAVFCLCLDDFPIKD 334
+S E P+ LTS+ R WAE R L+ S N +SL ++ + +CLD +
Sbjct: 338 KMASNEDERLPPIGLLTSDGRSEWAEARTVLVKDSTNRDSLDMIERCICLVCLDAPGGVE 397
Query: 335 L--VHLSHNMLHG-----DGTNRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEV 387
L H + +LHG +G NRW+DKS ++ +DG+ V EHS DG+ +++ +
Sbjct: 398 LSDTHRALQLLHGGGYSKNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHL 457
Query: 388 FKDSTQTPAVTPQSQPATTDSTVTVQKLNFELTDALKTGITAAKEKFDATMKTLTIDCVQ 447
K TQ+ ++ + ++L ++ + ++ + ++ EK +K L +
Sbjct: 458 LKHMTQSSRKLIRAD--SVSELPAPRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYK 515
Query: 448 FQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASV 507
F GK F+KKQK SPDA Q+A Q+AF R + + V TYES S F+ GR + IR A+
Sbjct: 516 FDNYGKTFIKKQKCSPDAFIQVALQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATP 575
Query: 508 YTKRCSEAFVREPSRHS----AGELQQMMVECSKYHGQLTKEAAMGQGFDRHLFALRHLA 563
+ AFVR + H A E ++ + + T A G D HL ALR LA
Sbjct: 576 E----ALAFVRAVTDHKAAVPASEKLLLLKDAIRAQTAYTVMAITGMAIDNHLLALRELA 631
Query: 564 AAKGIILPELYLDPAYGQINHNVLSTSTLSSPAVNLGGFAPVVSDGFGVGYAVHDNWIGC 623
A LPE+++D Y N VLSTS + + + PVV +G+G Y I
Sbjct: 632 RAMCKELPEMFMDETYLMSNRFVLSTSQVPTTTEMFCCYGPVVPNGYGACYNPQPETILF 691
Query: 624 NVSSYPG---RNAREFLQCVEKALEDMFD 649
+SS+ ++ +F + VE++L DM D
Sbjct: 692 CISSFHSCKETSSSKFAKAVEESLIDMRD 720
>gi|31542325 peroxisomal carnitine O-octanoyltransferase isoform 2
[Homo sapiens]
Length = 612
Score = 237 bits (604), Expect = 3e-62
Identities = 186/634 (29%), Positives = 307/634 (48%), Gaps = 63/634 (9%)
Query: 42 TMHYQDSLPRLPIPKLEDTIRRYLSAQKPLLNDGQFRKTEQFCKSFENGIGKELHEQLVA 101
T YQDSLP LP+P LE+++++YL + KP N +++KTE+ + F++GIG++LH++L
Sbjct: 13 TFQYQDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTEEIVQKFQSGIGEKLHQKL-- 70
Query: 102 LDKQNKHTSYISGPWFDM-YLSARDSVVLNFN---PFMAFNPDPKSEYNDQLTRATNMTV 157
L++ +++ W ++ YL R LN N P F + QL R +
Sbjct: 71 LERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLW 130
Query: 158 SAIRFLKTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQY 217
+ + + LR VP + V PLDM+Q+
Sbjct: 131 HNLNYWQLLRK------------------------EKVP-------VHKVGNTPLDMNQF 159
Query: 218 FRLFNSTRLPKPSRDELF----TDDKAR---HLLVLRKGNFYIFDVLDQDGNIVSPSEIQ 270
LF++ ++P +RD + T+ + R H++VL +G ++FDV+ +G +V+P E+
Sbjct: 160 RMLFSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVI-HEGCLVTPPELL 218
Query: 271 AHLKYILSDSSPAPEFP-LAYLTSENRDIWAELRQKLMSSGNEES--LRKVDSAVFCLCL 327
L YI P+ P +A LTSE R WA+ R+ L+ E L K+ S++ +
Sbjct: 219 RQLTYIHKKCHSEPDGPGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSM 278
Query: 328 DD----FPIKDLVHLSHNMLHGDGTNRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRF 383
+D +D + +L GD T RW DKS+NLI +G + +H+ D + ++
Sbjct: 279 EDSSPHVTPEDYSEIIAAILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNI 338
Query: 384 FNEVFKDSTQTPAVTPQSQPATTDSTVTVQKLNFELTDALKTGITAAKEKFDATMKTLTI 443
V + Q S+ ++L F + + + I AK ++ L I
Sbjct: 339 SYYVDEKIFQNEGRWKGSEKVR--DIPLPEELIFIVDEKVLNDINQAKAQYLREASDLQI 396
Query: 444 DCVQFQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIR 503
F GK+ K + L PD QLA Q+A+ R +G YE+ T F HGRTET+R
Sbjct: 397 AAYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMR 456
Query: 504 PASVYTKRCSEAFVREPSRHSAGELQQMMVECSKYHGQLTKEAAMGQGFDRHLFALRHLA 563
+V R ++ +++PS + E QQ M++ H ++ K+ + G+GFDRHL L +A
Sbjct: 457 SCTVEAVRWCQS-MQDPS-VNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIA 514
Query: 564 AAKGIILPELYLDPAY---GQINHNVLSTSTLSSPAVNLGGFAPVVSDGFGVGYAVHDN- 619
+G+ +PEL+ DP + G + VLSTS + V G P+V +G+G Y + D+
Sbjct: 515 KEEGLPVPELFTDPLFSKSGGGGNFVLSTSLVGYLRVQ-GVVVPMVHNGYGFFYHIRDDR 573
Query: 620 -WIGCNV-SSYPGRNAREFLQCVEKALEDMFDAL 651
+ C+ S P +A + +Q A DM +
Sbjct: 574 FVVACSAWKSCPETDAEKLVQLTFCAFHDMIQLM 607
>gi|223468672 carnitine palmitoyltransferase 1B isoform a [Homo
sapiens]
Length = 772
Score = 227 bits (579), Expect = 2e-59
Identities = 187/645 (28%), Positives = 299/645 (46%), Gaps = 84/645 (13%)
Query: 45 YQDSLPRLPIPKLEDTIRRYLSAQKPLLNDGQFRKTEQFCKSFENGIGKELHEQLVALDK 104
+Q SLP+LP+P++ TI+RYL + +PLL+D ++ + E K F++ L + LV K
Sbjct: 169 FQTSLPKLPVPRVSATIQRYLESVRPLLDDEEYYRMELLAKEFQDKTAPRLQKYLVL--K 226
Query: 105 QNKHTSYISGPWFD-MYLSARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNMTVSAIRFL 163
++Y+S W + +YL R +++N N ++ L N V A R
Sbjct: 227 SWWASNYVSDWWEEYIYLRGRSPLMVNSNYYVM-----------DLVLIKNTDVQAARLG 275
Query: 164 KTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNS 223
+ A ++ K D K ++ + P+ Q R+FN+
Sbjct: 276 NIIHAMIMYRR-------KLDREEIKPVMA-------------LGIVPMCSYQMERMFNT 315
Query: 224 TRLPKPSRDELFTDDKARHLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYILSDSSPA 283
TR+P D L +RH+ V KG F+ L + ++ P +++ + IL D SP
Sbjct: 316 TRIPGKDTDVLQHLSDSRHVAVYHKGRFFKL-WLYEGARLLKPQDLEMQFQRILDDPSPP 374
Query: 284 P--EFPLAYLTSENRDIWAELRQKLMSSG-NEESLRKVDSAVFCLCLDD----FPIKDLV 336
E LA LT+ R WA+ RQ SSG N+ +L ++ A F + LD+ + +D
Sbjct: 375 QPGEEKLAALTAGGRVEWAQARQAFFSSGKNKAALEAIERAAFFVALDEESYSYDPEDEA 434
Query: 337 HLS---HNMLHGDGTNRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEVF-KDS- 391
LS +LHG+ NRWFDKSF LI K+G ++ EH+W D + + V DS
Sbjct: 435 SLSLYGKALLHGNCYNRWFDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEFVLGTDSF 494
Query: 392 ----TQTPAVTPQSQPATTDSTVTVQKLNFELTDALKTGITAAKEKFDATMKTLTIDCVQ 447
T+T + PA T +L +++ + I ++ + A + + C Q
Sbjct: 495 HLGYTETGHCLGKPNPALAPPT----RLQWDIPKQCQAVIESSYQVAKALADDVELYCFQ 550
Query: 448 FQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASV 507
F GK +KK + SPDA Q+A Q+A R G+ TYE+ T F+ GRTET+R +
Sbjct: 551 FLPFGKGLIKKCRTSPDAFVQIALQLAHFRDRGKFCLTYEASMTRMFREGRTETVRSCTS 610
Query: 508 YTKRCSEAFVREPSRHSAGELQQMMVECSKYHGQLTKEAAMGQGFDRHLFALRHLAAAKG 567
+ +A + H+ +L+ + + +K H + + A G G DRHLF L ++ G
Sbjct: 611 ESTAFVQAMME--GSHTKADLRDLFQKAAKKHQNMYRLAMTGAGIDRHLFCLYLVSKYLG 668
Query: 568 I---ILPELYLDPAYGQINHNVLSTSTLSSPAVNL-------------GGFAPVVSDGFG 611
+ L E+ +P LSTS + + + GGF PV DG+G
Sbjct: 669 VSSPFLAEVLSEPWR-------LSTSQIPQSQIRMFDPEQHPNHLGAGGGFGPVADDGYG 721
Query: 612 VGYAV-HDNWIGCNVS---SYPGRNAREFLQCVEKALEDMFDALE 652
V Y + +N I ++S S NA+ F + KAL D+ D +
Sbjct: 722 VSYMIAGENTIFFHISSKFSSSETNAQRFGNHIRKALLDIADLFQ 766
>gi|23238254 carnitine palmitoyltransferase 1B isoform a [Homo
sapiens]
Length = 772
Score = 227 bits (579), Expect = 2e-59
Identities = 187/645 (28%), Positives = 299/645 (46%), Gaps = 84/645 (13%)
Query: 45 YQDSLPRLPIPKLEDTIRRYLSAQKPLLNDGQFRKTEQFCKSFENGIGKELHEQLVALDK 104
+Q SLP+LP+P++ TI+RYL + +PLL+D ++ + E K F++ L + LV K
Sbjct: 169 FQTSLPKLPVPRVSATIQRYLESVRPLLDDEEYYRMELLAKEFQDKTAPRLQKYLVL--K 226
Query: 105 QNKHTSYISGPWFD-MYLSARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNMTVSAIRFL 163
++Y+S W + +YL R +++N N ++ L N V A R
Sbjct: 227 SWWASNYVSDWWEEYIYLRGRSPLMVNSNYYVM-----------DLVLIKNTDVQAARLG 275
Query: 164 KTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNS 223
+ A ++ K D K ++ + P+ Q R+FN+
Sbjct: 276 NIIHAMIMYRR-------KLDREEIKPVMA-------------LGIVPMCSYQMERMFNT 315
Query: 224 TRLPKPSRDELFTDDKARHLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYILSDSSPA 283
TR+P D L +RH+ V KG F+ L + ++ P +++ + IL D SP
Sbjct: 316 TRIPGKDTDVLQHLSDSRHVAVYHKGRFFKL-WLYEGARLLKPQDLEMQFQRILDDPSPP 374
Query: 284 P--EFPLAYLTSENRDIWAELRQKLMSSG-NEESLRKVDSAVFCLCLDD----FPIKDLV 336
E LA LT+ R WA+ RQ SSG N+ +L ++ A F + LD+ + +D
Sbjct: 375 QPGEEKLAALTAGGRVEWAQARQAFFSSGKNKAALEAIERAAFFVALDEESYSYDPEDEA 434
Query: 337 HLS---HNMLHGDGTNRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEVF-KDS- 391
LS +LHG+ NRWFDKSF LI K+G ++ EH+W D + + V DS
Sbjct: 435 SLSLYGKALLHGNCYNRWFDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEFVLGTDSF 494
Query: 392 ----TQTPAVTPQSQPATTDSTVTVQKLNFELTDALKTGITAAKEKFDATMKTLTIDCVQ 447
T+T + PA T +L +++ + I ++ + A + + C Q
Sbjct: 495 HLGYTETGHCLGKPNPALAPPT----RLQWDIPKQCQAVIESSYQVAKALADDVELYCFQ 550
Query: 448 FQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASV 507
F GK +KK + SPDA Q+A Q+A R G+ TYE+ T F+ GRTET+R +
Sbjct: 551 FLPFGKGLIKKCRTSPDAFVQIALQLAHFRDRGKFCLTYEASMTRMFREGRTETVRSCTS 610
Query: 508 YTKRCSEAFVREPSRHSAGELQQMMVECSKYHGQLTKEAAMGQGFDRHLFALRHLAAAKG 567
+ +A + H+ +L+ + + +K H + + A G G DRHLF L ++ G
Sbjct: 611 ESTAFVQAMME--GSHTKADLRDLFQKAAKKHQNMYRLAMTGAGIDRHLFCLYLVSKYLG 668
Query: 568 I---ILPELYLDPAYGQINHNVLSTSTLSSPAVNL-------------GGFAPVVSDGFG 611
+ L E+ +P LSTS + + + GGF PV DG+G
Sbjct: 669 VSSPFLAEVLSEPWR-------LSTSQIPQSQIRMFDPEQHPNHLGAGGGFGPVADDGYG 721
Query: 612 VGYAV-HDNWIGCNVS---SYPGRNAREFLQCVEKALEDMFDALE 652
V Y + +N I ++S S NA+ F + KAL D+ D +
Sbjct: 722 VSYMIAGENTIFFHISSKFSSSETNAQRFGNHIRKALLDIADLFQ 766
>gi|223468678 carnitine palmitoyltransferase 1B isoform a [Homo
sapiens]
Length = 772
Score = 227 bits (579), Expect = 2e-59
Identities = 187/645 (28%), Positives = 299/645 (46%), Gaps = 84/645 (13%)
Query: 45 YQDSLPRLPIPKLEDTIRRYLSAQKPLLNDGQFRKTEQFCKSFENGIGKELHEQLVALDK 104
+Q SLP+LP+P++ TI+RYL + +PLL+D ++ + E K F++ L + LV K
Sbjct: 169 FQTSLPKLPVPRVSATIQRYLESVRPLLDDEEYYRMELLAKEFQDKTAPRLQKYLVL--K 226
Query: 105 QNKHTSYISGPWFD-MYLSARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNMTVSAIRFL 163
++Y+S W + +YL R +++N N ++ L N V A R
Sbjct: 227 SWWASNYVSDWWEEYIYLRGRSPLMVNSNYYVM-----------DLVLIKNTDVQAARLG 275
Query: 164 KTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNS 223
+ A ++ K D K ++ + P+ Q R+FN+
Sbjct: 276 NIIHAMIMYRR-------KLDREEIKPVMA-------------LGIVPMCSYQMERMFNT 315
Query: 224 TRLPKPSRDELFTDDKARHLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYILSDSSPA 283
TR+P D L +RH+ V KG F+ L + ++ P +++ + IL D SP
Sbjct: 316 TRIPGKDTDVLQHLSDSRHVAVYHKGRFFKL-WLYEGARLLKPQDLEMQFQRILDDPSPP 374
Query: 284 P--EFPLAYLTSENRDIWAELRQKLMSSG-NEESLRKVDSAVFCLCLDD----FPIKDLV 336
E LA LT+ R WA+ RQ SSG N+ +L ++ A F + LD+ + +D
Sbjct: 375 QPGEEKLAALTAGGRVEWAQARQAFFSSGKNKAALEAIERAAFFVALDEESYSYDPEDEA 434
Query: 337 HLS---HNMLHGDGTNRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEVF-KDS- 391
LS +LHG+ NRWFDKSF LI K+G ++ EH+W D + + V DS
Sbjct: 435 SLSLYGKALLHGNCYNRWFDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEFVLGTDSF 494
Query: 392 ----TQTPAVTPQSQPATTDSTVTVQKLNFELTDALKTGITAAKEKFDATMKTLTIDCVQ 447
T+T + PA T +L +++ + I ++ + A + + C Q
Sbjct: 495 HLGYTETGHCLGKPNPALAPPT----RLQWDIPKQCQAVIESSYQVAKALADDVELYCFQ 550
Query: 448 FQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASV 507
F GK +KK + SPDA Q+A Q+A R G+ TYE+ T F+ GRTET+R +
Sbjct: 551 FLPFGKGLIKKCRTSPDAFVQIALQLAHFRDRGKFCLTYEASMTRMFREGRTETVRSCTS 610
Query: 508 YTKRCSEAFVREPSRHSAGELQQMMVECSKYHGQLTKEAAMGQGFDRHLFALRHLAAAKG 567
+ +A + H+ +L+ + + +K H + + A G G DRHLF L ++ G
Sbjct: 611 ESTAFVQAMME--GSHTKADLRDLFQKAAKKHQNMYRLAMTGAGIDRHLFCLYLVSKYLG 668
Query: 568 I---ILPELYLDPAYGQINHNVLSTSTLSSPAVNL-------------GGFAPVVSDGFG 611
+ L E+ +P LSTS + + + GGF PV DG+G
Sbjct: 669 VSSPFLAEVLSEPWR-------LSTSQIPQSQIRMFDPEQHPNHLGAGGGFGPVADDGYG 721
Query: 612 VGYAV-HDNWIGCNVS---SYPGRNAREFLQCVEKALEDMFDALE 652
V Y + +N I ++S S NA+ F + KAL D+ D +
Sbjct: 722 VSYMIAGENTIFFHISSKFSSSETNAQRFGNHIRKALLDIADLFQ 766
>gi|4758050 carnitine palmitoyltransferase 1B isoform a [Homo
sapiens]
Length = 772
Score = 227 bits (579), Expect = 2e-59
Identities = 187/645 (28%), Positives = 299/645 (46%), Gaps = 84/645 (13%)
Query: 45 YQDSLPRLPIPKLEDTIRRYLSAQKPLLNDGQFRKTEQFCKSFENGIGKELHEQLVALDK 104
+Q SLP+LP+P++ TI+RYL + +PLL+D ++ + E K F++ L + LV K
Sbjct: 169 FQTSLPKLPVPRVSATIQRYLESVRPLLDDEEYYRMELLAKEFQDKTAPRLQKYLVL--K 226
Query: 105 QNKHTSYISGPWFD-MYLSARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNMTVSAIRFL 163
++Y+S W + +YL R +++N N ++ L N V A R
Sbjct: 227 SWWASNYVSDWWEEYIYLRGRSPLMVNSNYYVM-----------DLVLIKNTDVQAARLG 275
Query: 164 KTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNS 223
+ A ++ K D K ++ + P+ Q R+FN+
Sbjct: 276 NIIHAMIMYRR-------KLDREEIKPVMA-------------LGIVPMCSYQMERMFNT 315
Query: 224 TRLPKPSRDELFTDDKARHLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYILSDSSPA 283
TR+P D L +RH+ V KG F+ L + ++ P +++ + IL D SP
Sbjct: 316 TRIPGKDTDVLQHLSDSRHVAVYHKGRFFKL-WLYEGARLLKPQDLEMQFQRILDDPSPP 374
Query: 284 P--EFPLAYLTSENRDIWAELRQKLMSSG-NEESLRKVDSAVFCLCLDD----FPIKDLV 336
E LA LT+ R WA+ RQ SSG N+ +L ++ A F + LD+ + +D
Sbjct: 375 QPGEEKLAALTAGGRVEWAQARQAFFSSGKNKAALEAIERAAFFVALDEESYSYDPEDEA 434
Query: 337 HLS---HNMLHGDGTNRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEVF-KDS- 391
LS +LHG+ NRWFDKSF LI K+G ++ EH+W D + + V DS
Sbjct: 435 SLSLYGKALLHGNCYNRWFDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEFVLGTDSF 494
Query: 392 ----TQTPAVTPQSQPATTDSTVTVQKLNFELTDALKTGITAAKEKFDATMKTLTIDCVQ 447
T+T + PA T +L +++ + I ++ + A + + C Q
Sbjct: 495 HLGYTETGHCLGKPNPALAPPT----RLQWDIPKQCQAVIESSYQVAKALADDVELYCFQ 550
Query: 448 FQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASV 507
F GK +KK + SPDA Q+A Q+A R G+ TYE+ T F+ GRTET+R +
Sbjct: 551 FLPFGKGLIKKCRTSPDAFVQIALQLAHFRDRGKFCLTYEASMTRMFREGRTETVRSCTS 610
Query: 508 YTKRCSEAFVREPSRHSAGELQQMMVECSKYHGQLTKEAAMGQGFDRHLFALRHLAAAKG 567
+ +A + H+ +L+ + + +K H + + A G G DRHLF L ++ G
Sbjct: 611 ESTAFVQAMME--GSHTKADLRDLFQKAAKKHQNMYRLAMTGAGIDRHLFCLYLVSKYLG 668
Query: 568 I---ILPELYLDPAYGQINHNVLSTSTLSSPAVNL-------------GGFAPVVSDGFG 611
+ L E+ +P LSTS + + + GGF PV DG+G
Sbjct: 669 VSSPFLAEVLSEPWR-------LSTSQIPQSQIRMFDPEQHPNHLGAGGGFGPVADDGYG 721
Query: 612 VGYAV-HDNWIGCNVS---SYPGRNAREFLQCVEKALEDMFDALE 652
V Y + +N I ++S S NA+ F + KAL D+ D +
Sbjct: 722 VSYMIAGENTIFFHISSKFSSSETNAQRFGNHIRKALLDIADLFQ 766
>gi|23238256 carnitine palmitoyltransferase 1B isoform a [Homo
sapiens]
Length = 772
Score = 227 bits (579), Expect = 2e-59
Identities = 187/645 (28%), Positives = 299/645 (46%), Gaps = 84/645 (13%)
Query: 45 YQDSLPRLPIPKLEDTIRRYLSAQKPLLNDGQFRKTEQFCKSFENGIGKELHEQLVALDK 104
+Q SLP+LP+P++ TI+RYL + +PLL+D ++ + E K F++ L + LV K
Sbjct: 169 FQTSLPKLPVPRVSATIQRYLESVRPLLDDEEYYRMELLAKEFQDKTAPRLQKYLVL--K 226
Query: 105 QNKHTSYISGPWFD-MYLSARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNMTVSAIRFL 163
++Y+S W + +YL R +++N N ++ L N V A R
Sbjct: 227 SWWASNYVSDWWEEYIYLRGRSPLMVNSNYYVM-----------DLVLIKNTDVQAARLG 275
Query: 164 KTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNS 223
+ A ++ K D K ++ + P+ Q R+FN+
Sbjct: 276 NIIHAMIMYRR-------KLDREEIKPVMA-------------LGIVPMCSYQMERMFNT 315
Query: 224 TRLPKPSRDELFTDDKARHLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYILSDSSPA 283
TR+P D L +RH+ V KG F+ L + ++ P +++ + IL D SP
Sbjct: 316 TRIPGKDTDVLQHLSDSRHVAVYHKGRFFKL-WLYEGARLLKPQDLEMQFQRILDDPSPP 374
Query: 284 P--EFPLAYLTSENRDIWAELRQKLMSSG-NEESLRKVDSAVFCLCLDD----FPIKDLV 336
E LA LT+ R WA+ RQ SSG N+ +L ++ A F + LD+ + +D
Sbjct: 375 QPGEEKLAALTAGGRVEWAQARQAFFSSGKNKAALEAIERAAFFVALDEESYSYDPEDEA 434
Query: 337 HLS---HNMLHGDGTNRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEVF-KDS- 391
LS +LHG+ NRWFDKSF LI K+G ++ EH+W D + + V DS
Sbjct: 435 SLSLYGKALLHGNCYNRWFDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEFVLGTDSF 494
Query: 392 ----TQTPAVTPQSQPATTDSTVTVQKLNFELTDALKTGITAAKEKFDATMKTLTIDCVQ 447
T+T + PA T +L +++ + I ++ + A + + C Q
Sbjct: 495 HLGYTETGHCLGKPNPALAPPT----RLQWDIPKQCQAVIESSYQVAKALADDVELYCFQ 550
Query: 448 FQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASV 507
F GK +KK + SPDA Q+A Q+A R G+ TYE+ T F+ GRTET+R +
Sbjct: 551 FLPFGKGLIKKCRTSPDAFVQIALQLAHFRDRGKFCLTYEASMTRMFREGRTETVRSCTS 610
Query: 508 YTKRCSEAFVREPSRHSAGELQQMMVECSKYHGQLTKEAAMGQGFDRHLFALRHLAAAKG 567
+ +A + H+ +L+ + + +K H + + A G G DRHLF L ++ G
Sbjct: 611 ESTAFVQAMME--GSHTKADLRDLFQKAAKKHQNMYRLAMTGAGIDRHLFCLYLVSKYLG 668
Query: 568 I---ILPELYLDPAYGQINHNVLSTSTLSSPAVNL-------------GGFAPVVSDGFG 611
+ L E+ +P LSTS + + + GGF PV DG+G
Sbjct: 669 VSSPFLAEVLSEPWR-------LSTSQIPQSQIRMFDPEQHPNHLGAGGGFGPVADDGYG 721
Query: 612 VGYAV-HDNWIGCNVS---SYPGRNAREFLQCVEKALEDMFDALE 652
V Y + +N I ++S S NA+ F + KAL D+ D +
Sbjct: 722 VSYMIAGENTIFFHISSKFSSSETNAQRFGNHIRKALLDIADLFQ 766
>gi|221316602 peroxisomal carnitine O-octanoyltransferase isoform 1
[Homo sapiens]
Length = 640
Score = 222 bits (565), Expect = 1e-57
Identities = 186/662 (28%), Positives = 307/662 (46%), Gaps = 91/662 (13%)
Query: 42 TMHYQDSLPRLPIPKLEDTIRRYLSAQ----------------------------KPLLN 73
T YQDSLP LP+P LE+++++YL + KP N
Sbjct: 13 TFQYQDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDLTREGIQVKPFAN 72
Query: 74 DGQFRKTEQFCKSFENGIGKELHEQLVALDKQNKHTSYISGPWFDM-YLSARDSVVLNFN 132
+++KTE+ + F++GIG++LH++L L++ +++ W ++ YL R LN N
Sbjct: 73 QEEYKKTEEIVQKFQSGIGEKLHQKL--LERAKGKRNWLEEWWLNVAYLDVRIPSQLNVN 130
Query: 133 ---PFMAFNPDPKSEYNDQLTRATNMTVSAIRFLKTLRAGLLEPEVFHLNPAKSDTITFK 189
P F + QL R + + + + LR
Sbjct: 131 FAGPAAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRK--------------------- 169
Query: 190 RLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNSTRLPKPSRDELF----TDDKAR---H 242
VP + V PLDM+Q+ LF++ ++P +RD + T+ + R H
Sbjct: 170 ---EKVP-------VHKVGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNH 219
Query: 243 LLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYILSDSSPAPEFP-LAYLTSENRDIWAE 301
++VL +G ++FDV+ +G +V+P E+ L YI P+ P +A LTSE R WA+
Sbjct: 220 IVVLCRGRAFVFDVI-HEGCLVTPPELLRQLTYIHKKCHSEPDGPGIAALTSEERTRWAK 278
Query: 302 LRQKLMSSGNEES--LRKVDSAVFCLCLDD----FPIKDLVHLSHNMLHGDGTNRWFDKS 355
R+ L+ E L K+ S++ ++D +D + +L GD T RW DKS
Sbjct: 279 AREYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVTPEDYSEIIAAILIGDPTVRWGDKS 338
Query: 356 FNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEVFKDSTQTPAVTPQSQPATTDSTVTVQKL 415
+NLI +G + +H+ D + ++ V + Q S+ ++L
Sbjct: 339 YNLISFSNGVFGCNCDHAPFDAMIMVNISYYVDEKIFQNEGRWKGSEKVR--DIPLPEEL 396
Query: 416 NFELTDALKTGITAAKEKFDATMKTLTIDCVQFQRGGKEFLKKQKLSPDAVAQLAFQMAF 475
F + + + I AK ++ L I F GK+ K + L PD QLA Q+A+
Sbjct: 397 IFIVDEKVLNDINQAKAQYLREASDLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQLAY 456
Query: 476 LRQYGQTVATYESCSTAAFKHGRTETIRPASVYTKRCSEAFVREPSRHSAGELQQMMVEC 535
R +G YE+ T F HGRTET+R +V R ++ +++PS + E QQ M++
Sbjct: 457 YRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQS-MQDPS-VNLRERQQKMLQA 514
Query: 536 SKYHGQLTKEAAMGQGFDRHLFALRHLAAAKGIILPELYLDPAY---GQINHNVLSTSTL 592
H ++ K+ + G+GFDRHL L +A +G+ +PEL+ DP + G + VLSTS +
Sbjct: 515 FAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVPELFTDPLFSKSGGGGNFVLSTSLV 574
Query: 593 SSPAVNLGGFAPVVSDGFGVGYAVHDN--WIGCNV-SSYPGRNAREFLQCVEKALEDMFD 649
V G P+V +G+G Y + D+ + C+ S P +A + +Q A DM
Sbjct: 575 GYLRVQ-GVVVPMVHNGYGFFYHIRDDRFVVACSAWKSCPETDAEKLVQLTFCAFHDMIQ 633
Query: 650 AL 651
+
Sbjct: 634 LM 635
>gi|73623030 carnitine palmitoyltransferase 1A liver isoform 1 [Homo
sapiens]
Length = 773
Score = 207 bits (526), Expect = 3e-53
Identities = 176/637 (27%), Positives = 291/637 (45%), Gaps = 76/637 (11%)
Query: 45 YQDSLPRLPIPKLEDTIRRYLSAQKPLLNDGQFRKTEQFCKSFENGIGKELHEQLVALDK 104
+Q SLPRLP+P ++DT+ RYL + +PL+ + F++ + F G+G L L K
Sbjct: 167 FQTSLPRLPVPAVKDTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKL--K 224
Query: 105 QNKHTSYISGPWFD-MYLSARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNMTVSAIRFL 163
T+Y+S W + +YL R +++N N + A + + Q RA N + + +
Sbjct: 225 SWWATNYVSDWWEEYIYLRGRGPLMVNSN-YYAMDLLYILPTHIQAARAGNAIHAILLYR 283
Query: 164 KTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNS 223
+ L ++P IR + S++ PL +Q+ R+FN+
Sbjct: 284 RKLDREEIKP------------------IRLLGSTI-----------PLCSAQWERMFNT 314
Query: 224 TRLPKPSRDELFTDDKARHLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYILSDSS-P 282
+R+P D + ++H++V +G ++ L DG ++ P E++ ++ IL ++S P
Sbjct: 315 SRIPGEETDTIQHMRDSKHIVVYHRGRYFKV-WLYHDGRLLKPREMEQQMQRILDNTSEP 373
Query: 283 AP-EFPLAYLTSENRDIWAELRQKLMSSG-NEESLRKVDSAVFCLCLDDF--------PI 332
P E LA LT+ +R WA RQ G N++SL V+ A F + LD+ P
Sbjct: 374 QPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTLDETEEGYRSEDPD 433
Query: 333 KDLVHLSHNMLHGDGTNRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEVFK-DS 391
+ + ++LHG +RWFDKSF ++ K+G ++ EHSW D V + V DS
Sbjct: 434 TSMDSYAKSLLHGRCYDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDS 493
Query: 392 TQTPAVTPQSQPATTDSTVTVQ-KLNFELTDALKTGITAAKEKFDATMKTLTIDCVQFQR 450
Q + + +L +++ + I + + + F
Sbjct: 494 LQLGYAEDGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTANLLANDVDFHSFPFVA 553
Query: 451 GGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASVYTK 510
GK +KK + SPDA QLA Q+A + G+ TYE+ T F+ GRTET+R S T+
Sbjct: 554 FGKGIIKKCRTSPDAFVQLALQLAHYKDMGKFCLTYEASMTRLFREGRTETVR--SCTTE 611
Query: 511 RCSEAFVREPSRHSAGELQQMMVECSKYHGQLTKEAAMGQGFDRHLFALRHLA---AAKG 567
C + + ++ S+ H + + A G G DRHLF L ++ A +
Sbjct: 612 SCDFVRAMVDPAQTVEQRLKLFKLASEKHQHMYRLAMTGSGIDRHLFCLYVVSKYLAVES 671
Query: 568 IILPELYLDPAYGQINHNVLSTSTLSSPAVNL-------------GGFAPVVSDGFGVGY 614
L E+ +P LSTS V L GGF PV DG+GV Y
Sbjct: 672 PFLKEVLSEPWR-------LSTSQTPQQQVELFDLENNPEYVSSGGGFGPVADDGYGVSY 724
Query: 615 -AVHDNWIGCNVS---SYPGRNAREFLQCVEKALEDM 647
V +N I ++S S P ++ F + +++A+ D+
Sbjct: 725 ILVGENLINFHISSKFSCPETDSHRFGRHLKEAMTDI 761
>gi|73623028 carnitine palmitoyltransferase 1A liver isoform 2 [Homo
sapiens]
Length = 756
Score = 205 bits (521), Expect = 1e-52
Identities = 172/614 (28%), Positives = 279/614 (45%), Gaps = 73/614 (11%)
Query: 45 YQDSLPRLPIPKLEDTIRRYLSAQKPLLNDGQFRKTEQFCKSFENGIGKELHEQLVALDK 104
+Q SLPRLP+P ++DT+ RYL + +PL+ + F++ + F G+G L L K
Sbjct: 167 FQTSLPRLPVPAVKDTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKL--K 224
Query: 105 QNKHTSYISGPWFD-MYLSARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNMTVSAIRFL 163
T+Y+S W + +YL R +++N N + A + + Q RA N + + +
Sbjct: 225 SWWATNYVSDWWEEYIYLRGRGPLMVNSN-YYAMDLLYILPTHIQAARAGNAIHAILLYR 283
Query: 164 KTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNS 223
+ L ++P IR + S++ PL +Q+ R+FN+
Sbjct: 284 RKLDREEIKP------------------IRLLGSTI-----------PLCSAQWERMFNT 314
Query: 224 TRLPKPSRDELFTDDKARHLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYILSDSS-P 282
+R+P D + ++H++V +G ++ L DG ++ P E++ ++ IL ++S P
Sbjct: 315 SRIPGEETDTIQHMRDSKHIVVYHRGRYFKV-WLYHDGRLLKPREMEQQMQRILDNTSEP 373
Query: 283 AP-EFPLAYLTSENRDIWAELRQKLMSSG-NEESLRKVDSAVFCLCLDDF--------PI 332
P E LA LT+ +R WA RQ G N++SL V+ A F + LD+ P
Sbjct: 374 QPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTLDETEEGYRSEDPD 433
Query: 333 KDLVHLSHNMLHGDGTNRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEVFK-DS 391
+ + ++LHG +RWFDKSF ++ K+G ++ EHSW D V + V DS
Sbjct: 434 TSMDSYAKSLLHGRCYDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDS 493
Query: 392 TQTPAVTPQSQPATTDSTVTVQ-KLNFELTDALKTGITAAKEKFDATMKTLTIDCVQFQR 450
Q + + +L +++ + I + + + F
Sbjct: 494 LQLGYAEDGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTANLLANDVDFHSFPFVA 553
Query: 451 GGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASVYTK 510
GK +KK + SPDA QLA Q+A + G+ TYE+ T F+ GRTET+R S T+
Sbjct: 554 FGKGIIKKCRTSPDAFVQLALQLAHYKDMGKFCLTYEASMTRLFREGRTETVR--SCTTE 611
Query: 511 RCSEAFVREPSRHSAGELQQMMVECSKYHGQLTKEAAMGQGFDRHLFALRHLA---AAKG 567
C + + ++ S+ H + + A G G DRHLF L ++ A +
Sbjct: 612 SCDFVRAMVDPAQTVEQRLKLFKLASEKHQHMYRLAMTGSGIDRHLFCLYVVSKYLAVES 671
Query: 568 IILPELYLDPAYGQINHNVLSTSTLSSPAVNL-------------GGFAPVVSDGFGVGY 614
L E+ +P LSTS V L GGF PV DG+GV Y
Sbjct: 672 PFLKEVLSEPWR-------LSTSQTPQQQVELFDLENNPEYVSSGGGFGPVADDGYGVSY 724
Query: 615 -AVHDNWIGCNVSS 627
V +N I ++SS
Sbjct: 725 ILVGENLINFHISS 738
>gi|223468670 carnitine palmitoyltransferase 1B isoform c [Homo
sapiens]
Length = 738
Score = 204 bits (518), Expect = 3e-52
Identities = 177/626 (28%), Positives = 283/626 (45%), Gaps = 84/626 (13%)
Query: 64 YLSAQKPLLNDGQFRKTEQFCKSFENGIGKELHEQLVALDKQNKHTSYISGPWFD-MYLS 122
YL + +PLL+D ++ + E K F++ L + LV K ++Y+S W + +YL
Sbjct: 154 YLESVRPLLDDEEYYRMELLAKEFQDKTAPRLQKYLVL--KSWWASNYVSDWWEEYIYLR 211
Query: 123 ARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNMTVSAIRFLKTLRAGLLEPEVFHLNPAK 182
R +++N N ++ L N V A R + A ++ K
Sbjct: 212 GRSPLMVNSNYYVM-----------DLVLIKNTDVQAARLGNIIHAMIMYRR-------K 253
Query: 183 SDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNSTRLPKPSRDELFTDDKARH 242
D K ++ + P+ Q R+FN+TR+P D L +RH
Sbjct: 254 LDREEIKPVMA-------------LGIVPMCSYQMERMFNTTRIPGKDTDVLQHLSDSRH 300
Query: 243 LLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYILSDSSPAP--EFPLAYLTSENRDIWA 300
+ V KG F+ L + ++ P +++ + IL D SP E LA LT+ R WA
Sbjct: 301 VAVYHKGRFFKL-WLYEGARLLKPQDLEMQFQRILDDPSPPQPGEEKLAALTAGGRVEWA 359
Query: 301 ELRQKLMSSG-NEESLRKVDSAVFCLCLDD----FPIKDLVHLS---HNMLHGDGTNRWF 352
+ RQ SSG N+ +L ++ A F + LD+ + +D LS +LHG+ NRWF
Sbjct: 360 QARQAFFSSGKNKAALEAIERAAFFVALDEESYSYDPEDEASLSLYGKALLHGNCYNRWF 419
Query: 353 DKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEVF-KDS-----TQTPAVTPQSQPATT 406
DKSF LI K+G ++ EH+W D + + V DS T+T + PA
Sbjct: 420 DKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEFVLGTDSFHLGYTETGHCLGKPNPALA 479
Query: 407 DSTVTVQKLNFELTDALKTGITAAKEKFDATMKTLTIDCVQFQRGGKEFLKKQKLSPDAV 466
T +L +++ + I ++ + A + + C QF GK +KK + SPDA
Sbjct: 480 PPT----RLQWDIPKQCQAVIESSYQVAKALADDVELYCFQFLPFGKGLIKKCRTSPDAF 535
Query: 467 AQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASVYTKRCSEAFVREPSRHSAG 526
Q+A Q+A R G+ TYE+ T F+ GRTET+R + + +A + H+
Sbjct: 536 VQIALQLAHFRDRGKFCLTYEASMTRMFREGRTETVRSCTSESTAFVQAMME--GSHTKA 593
Query: 527 ELQQMMVECSKYHGQLTKEAAMGQGFDRHLFALRHLAAAKGI---ILPELYLDPAYGQIN 583
+L+ + + +K H + + A G G DRHLF L ++ G+ L E+ +P
Sbjct: 594 DLRDLFQKAAKKHQNMYRLAMTGAGIDRHLFCLYLVSKYLGVSSPFLAEVLSEPWR---- 649
Query: 584 HNVLSTSTLSSPAVNL-------------GGFAPVVSDGFGVGYAV-HDNWIGCNVS--- 626
LSTS + + + GGF PV DG+GV Y + +N I ++S
Sbjct: 650 ---LSTSQIPQSQIRMFDPEQHPNHLGAGGGFGPVADDGYGVSYMIAGENTIFFHISSKF 706
Query: 627 SYPGRNAREFLQCVEKALEDMFDALE 652
S NA+ F + KAL D+ D +
Sbjct: 707 SSSETNAQRFGNHIRKALLDIADLFQ 732
>gi|22748777 carnitine palmitoyltransferase 1C isoform 2 [Homo
sapiens]
Length = 803
Score = 199 bits (506), Expect = 7e-51
Identities = 187/642 (29%), Positives = 289/642 (45%), Gaps = 89/642 (13%)
Query: 45 YQDSLPRLPIPKLEDTIRRYLSAQKPLLNDGQFRKTEQFCKSFENGIGKELHEQLVALDK 104
YQ SLPR P+P ++DT+R+YL + +P+L+D F T + F + L + + L K
Sbjct: 167 YQRSLPRQPVPSVQDTVRKYLESVRPILSDEDFDWTAVLAQEFLR-LQASLLQWYLRL-K 224
Query: 105 QNKHTSYISGPWFD-MYLSARDSVVLNFN----PFMAFNPDPKSEYNDQLTRATNMTVSA 159
++Y+S W + +YL +R+ +++N N F+ P P Q RA N A
Sbjct: 225 SWWASNYVSDWWEEFVYLRSRNPLMVNSNYYMMDFLYVTPTPL-----QAARAGN----A 275
Query: 160 IRFLKTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFR 219
+ L R L E+ P +L L+ PL +QY +
Sbjct: 276 VHALLLYRHRLNRQEI--------------------PPTL------LMGMRPLCSAQYEK 309
Query: 220 LFNSTRLPKPSRDELFTDDKARHLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYILSD 279
+FN+TR+P +D + ++H+ V +G F+ ++ +++SP ++ + IL D
Sbjct: 310 IFNTTRIPGVQKDYIRHLHDSQHVAVFHRGRFFRMGTHSRN-SLLSPRALEQQFQRILDD 368
Query: 280 SSPA--PEFPLAYLTSENRDIWAELRQKLMSSGNEESLRKVDSAVFCLCLD--------D 329
SPA E LA LT+ R WA++R L + E+L V+ A F + LD +
Sbjct: 369 PSPACPHEEHLAALTAAPRGTWAQVRTSLKTQA-AEALEAVEGAAFFVSLDAEPAGLTRE 427
Query: 330 FPIKDLVHLSHNMLHGDGTNRWFDKSFNLIIAKDGSTAVHFEHSWGD-GVAVLRFFNEVF 388
P L +H +L G G +RWFDKSF LI+ +G + EHSW D ++ + +
Sbjct: 428 DPAASLDAYAHALLAGRGHDRWFDKSFTLIVFSNGKLGLSVEHSWADCPISGHMWEFTLA 487
Query: 389 KDSTQTPAVTPQSQPATTDSTVTV-QKLNFELTDALKTGITAAKEKFDATMKTLTIDC-- 445
+ Q T D T+ Q+L ++L D + + I+ A A + + +DC
Sbjct: 488 TECFQLGYSTDGHCKGHPDPTLPQPQRLQWDLPDQIHSSISLALR--GAKILSENVDCHV 545
Query: 446 VQFQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPA 505
V F GK F+++ LS D+ Q+A Q+A R GQ TYES T F GRTET+R
Sbjct: 546 VPFSLFGKSFIRRCHLSSDSFIQIALQLAHFRDRGQFCLTYESAMTRLFLEGRTETVR-- 603
Query: 506 SVYTKRCSEAFVREPSRHSAGELQQMMVECSKYHGQLTKEAAMGQGFDRHLFALRHLAAA 565
S + C+ E + + + H L K A GQG DRHLFAL
Sbjct: 604 SCTREACNFVRAMEDKEKTDPQCLALFRVAVDKHQALLKAAMSGQGVDRHLFALY----- 658
Query: 566 KGIILPELYL-DPAYGQINHNVLSTSTLSSPAVNL---------------GGFAPVVSDG 609
I+ L+L P Q++ ST P + GGF P G
Sbjct: 659 --IVSRFLHLQSPFLTQVHSEQWQLSTSQIPVQQMHLFDVHNYPDYVSSGGGFGPADDHG 716
Query: 610 FGVGYA-VHDNWIGCNVSSYPG---RNAREFLQCVEKALEDM 647
+GV Y + D I ++SS ++ Q +E AL D+
Sbjct: 717 YGVSYIFMGDGMITFHISSKKSSTKTDSHRLGQHIEDALLDV 758
>gi|209862905 carnitine palmitoyltransferase 1C isoform 1 [Homo
sapiens]
Length = 792
Score = 196 bits (499), Expect = 4e-50
Identities = 184/638 (28%), Positives = 286/638 (44%), Gaps = 92/638 (14%)
Query: 45 YQDSLPRLPIPKLEDTIRRYLSAQKPLLNDGQFRKTEQFCKSFENGIGKELHEQLVALDK 104
YQ SLPR P+P ++DT+R+YL + +P+L+D F T + F + L + + L K
Sbjct: 167 YQRSLPRQPVPSVQDTVRKYLESVRPILSDEDFDWTAVLAQEFLR-LQASLLQWYLRL-K 224
Query: 105 QNKHTSYISGPWFD-MYLSARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNMTVSAIRFL 163
++Y+S W + +YL +R+ +++N N +M RA N A+ L
Sbjct: 225 SWWASNYVSDWWEEFVYLRSRNPLMVNSNYYM------------MAARAGN----AVHAL 268
Query: 164 KTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNS 223
R L E+ P +L L+ PL +QY ++FN+
Sbjct: 269 LLYRHRLNRQEI--------------------PPTL------LMGMRPLCSAQYEKIFNT 302
Query: 224 TRLPKPSRDELFTDDKARHLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYILSDSSPA 283
TR+P +D + ++H+ V +G F+ ++ +++SP ++ + IL D SPA
Sbjct: 303 TRIPGVQKDYIRHLHDSQHVAVFHRGRFFRMGTHSRN-SLLSPRALEQQFQRILDDPSPA 361
Query: 284 --PEFPLAYLTSENRDIWAELRQKLMSSGNEESLRKVDSAVFCLCLD--------DFPIK 333
E LA LT+ R WA++R L + E+L V+ A F + LD + P
Sbjct: 362 CPHEEHLAALTAAPRGTWAQVRTSLKTQA-AEALEAVEGAAFFVSLDAEPAGLTREDPAA 420
Query: 334 DLVHLSHNMLHGDGTNRWFDKSFNLIIAKDGSTAVHFEHSWGD-GVAVLRFFNEVFKDST 392
L +H +L G G +RWFDKSF LI+ +G + EHSW D ++ + + +
Sbjct: 421 SLDAYAHALLAGRGHDRWFDKSFTLIVFSNGKLGLSVEHSWADCPISGHMWEFTLATECF 480
Query: 393 QTPAVTPQSQPATTDSTVTV-QKLNFELTDALKTGITAAKEKFDATMKTLTIDC--VQFQ 449
Q T D T+ Q+L ++L D + + I+ A A + + +DC V F
Sbjct: 481 QLGYSTDGHCKGHPDPTLPQPQRLQWDLPDQIHSSISLALR--GAKILSENVDCHVVPFS 538
Query: 450 RGGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASVYT 509
GK F+++ LS D+ Q+A Q+A R GQ TYES T F GRTET+R S
Sbjct: 539 LFGKSFIRRCHLSSDSFIQIALQLAHFRDRGQFCLTYESAMTRLFLEGRTETVR--SCTR 596
Query: 510 KRCSEAFVREPSRHSAGELQQMMVECSKYHGQLTKEAAMGQGFDRHLFALRHLAAAKGII 569
+ C+ E + + + H L K A GQG DRHLFAL I+
Sbjct: 597 EACNFVRAMEDKEKTDPQCLALFRVAVDKHQALLKAAMSGQGVDRHLFALY-------IV 649
Query: 570 LPELYL-DPAYGQINHNVLSTSTLSSPAVNL---------------GGFAPVVSDGFGVG 613
L+L P Q++ ST P + GGF P G+GV
Sbjct: 650 SRFLHLQSPFLTQVHSEQWQLSTSQIPVQQMHLFDVHNYPDYVSSGGGFGPADDHGYGVS 709
Query: 614 YA-VHDNWIGCNVSSYPG---RNAREFLQCVEKALEDM 647
Y + D I ++SS ++ Q +E AL D+
Sbjct: 710 YIFMGDGMITFHISSKKSSTKTDSHRLGQHIEDALLDV 747
>gi|223468674 carnitine palmitoyltransferase 1B isoform d [Homo
sapiens]
Length = 691
Score = 137 bits (346), Expect = 2e-32
Identities = 102/337 (30%), Positives = 159/337 (47%), Gaps = 39/337 (11%)
Query: 342 MLHGDGTNRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEVF-KDS-----TQTP 395
+LHG+ NRWFDKSF LI K+G ++ EH+W D + + V DS T+T
Sbjct: 362 LLHGNCYNRWFDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEFVLGTDSFHLGYTETG 421
Query: 396 AVTPQSQPATTDSTVTVQKLNFELTDALKTGITAAKEKFDATMKTLTIDCVQFQRGGKEF 455
+ PA T +L +++ + I ++ + A + + C QF GK
Sbjct: 422 HCLGKPNPALAPPT----RLQWDIPKQCQAVIESSYQVAKALADDVELYCFQFLPFGKGL 477
Query: 456 LKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASVYTKRCSEA 515
+KK + SPDA Q+A Q+A R G+ TYE+ T F+ GRTET+R + + +A
Sbjct: 478 IKKCRTSPDAFVQIALQLAHFRDRGKFCLTYEASMTRMFREGRTETVRSCTSESTAFVQA 537
Query: 516 FVREPSRHSAGELQQMMVECSKYHGQLTKEAAMGQGFDRHLFALRHLAAAKGI---ILPE 572
+ H+ +L+ + + +K H + + A G G DRHLF L ++ G+ L E
Sbjct: 538 MME--GSHTKADLRDLFQKAAKKHQNMYRLAMTGAGIDRHLFCLYLVSKYLGVSSPFLAE 595
Query: 573 LYLDPAYGQINHNVLSTSTLSSPAVNL-------------GGFAPVVSDGFGVGYAV-HD 618
+ +P LSTS + + + GGF PV DG+GV Y + +
Sbjct: 596 VLSEPWR-------LSTSQIPQSQIRMFDPEQHPNHLGAGGGFGPVADDGYGVSYMIAGE 648
Query: 619 NWIGCNVS---SYPGRNAREFLQCVEKALEDMFDALE 652
N I ++S S NA+ F + KAL D+ D +
Sbjct: 649 NTIFFHISSKFSSSETNAQRFGNHIRKALLDIADLFQ 685
Score = 70.9 bits (172), Expect = 4e-12
Identities = 56/209 (26%), Positives = 94/209 (44%), Gaps = 34/209 (16%)
Query: 45 YQDSLPRLPIPKLEDTIRRYLSAQKPLLNDGQFRKTEQFCKSFENGIGKELHEQLVALDK 104
+Q SLP+LP+P++ TI+RYL + +PLL+D ++ + E K F++ L + LV K
Sbjct: 169 FQTSLPKLPVPRVSATIQRYLESVRPLLDDEEYYRMELLAKEFQDKTAPRLQKYLVL--K 226
Query: 105 QNKHTSYISGPWFD-MYLSARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNMTVSAIRFL 163
++Y+S W + +YL R +++N N ++ L N V A R
Sbjct: 227 SWWASNYVSDWWEEYIYLRGRSPLMVNSNYYVM-----------DLVLIKNTDVQAARLG 275
Query: 164 KTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNS 223
+ A ++ K D K ++ + P+ Q R+FN+
Sbjct: 276 NIIHAMIMYRR-------KLDREEIKPVM-------------ALGIVPMCSYQMERMFNT 315
Query: 224 TRLPKPSRDELFTDDKARHLLVLRKGNFY 252
TR+P D L +RH+ V KG F+
Sbjct: 316 TRIPGKDTDVLQHLSDSRHVAVYHKGRFF 344
>gi|239749124 PREDICTED: zinc finger protein 716 [Homo sapiens]
Length = 1215
Score = 32.7 bits (73), Expect = 1.1
Identities = 14/26 (53%), Positives = 19/26 (73%)
Query: 2 VPRLLLRAWPRGPAVGPGAPSRPLSA 27
V ++LLRAWP+ P V PGAP+ +A
Sbjct: 533 VVQILLRAWPQRPMVHPGAPATVTTA 558
>gi|122937211 KIAA0368 protein [Homo sapiens]
Length = 2017
Score = 32.7 bits (73), Expect = 1.1
Identities = 34/126 (26%), Positives = 54/126 (42%), Gaps = 16/126 (12%)
Query: 10 WP--RGPAVGPGAPSRPLSAGSGPGQYLQRSIVPTMHYQDSLPRLPIPKLEDTIRRYLSA 67
WP RG AV PG P RP S G + R+ T + RL + ++ ++ +S
Sbjct: 153 WPCARGGAVRPGRPHRPPRVESARGAHAGRA--ATDQLERVFLRLGHAETDEQLQNIISK 210
Query: 68 QKP--LLNDGQFRKTEQFCKSFENGIGKELHEQLVALDKQNKHTSYISGPWFDMYLSARD 125
P LL S + G+ K++ E LV L+K+ K I P + + +D
Sbjct: 211 FLPPVLLK----------LSSTQEGVRKKVMELLVHLNKRIKSRPKIQLPVETLLVQYQD 260
Query: 126 SVVLNF 131
++F
Sbjct: 261 PAAVSF 266
>gi|13787217 FAT tumor suppressor 2 precursor [Homo sapiens]
Length = 4349
Score = 32.3 bits (72), Expect = 1.4
Identities = 39/184 (21%), Positives = 72/184 (39%), Gaps = 20/184 (10%)
Query: 248 KGNFYIFDVLDQDGNIVSPSEIQAHLKYILSDS-SPAPEFPLAYLTSENRDIWAELRQKL 306
K NF + +DGN+ P Q H + + D+ +P E +R + AE+ L
Sbjct: 1535 KRNFVWVTIHVEDGNLHPPRFTQLHYEASVPDTIAPGTELLQVRAMDADRGVNAEVHYSL 1594
Query: 307 MSSGNEESLRKVDSAVFCLCLDDFPIKDLVHLSHNM---LHGDGTNRWFDKSFNLIIAKD 363
+ GN E +++ + + L + H H + G+ +W D +
Sbjct: 1595 L-KGNSEGFFNINALLGIITLAQ-KLDQANHAPHTLTVKAEDQGSPQWHDLA-------- 1644
Query: 364 GSTAVHFEHSWGDGVAVLRFFNEVFKDSTQTPAVTPQSQPATTDSTVTVQKLNFELTDAL 423
+ +H S D A + +E F + P P P S ++ ++ +EL +
Sbjct: 1645 -TVIIHVYPS--DRSAPIFSKSEYF---VEIPESIPVGSPILLVSAMSPSEVTYELREGN 1698
Query: 424 KTGI 427
K G+
Sbjct: 1699 KDGV 1702
>gi|60498978 elastin microfibril interfacer 2 [Homo sapiens]
Length = 1053
Score = 32.0 bits (71), Expect = 1.9
Identities = 27/124 (21%), Positives = 56/124 (45%), Gaps = 13/124 (10%)
Query: 279 DSSPAPEFPLAYLTSENRDIWAELRQKLMS---------SGNEESLRKVDSAVFCLCLDD 329
D+ P+P+ P+A+ S+ + W L+ +++S G + + V+ V + +
Sbjct: 654 DTLPSPQHPVAHCCSQLEERWQRLQSQVISELDACKECTQGVQREVSMVEGRVSHM---E 710
Query: 330 FPIKDLVHLSHNMLH-GDGTNRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEVF 388
L +S N+ +G N+ +N + +G+ H G +V +F++ VF
Sbjct: 711 KTCSKLDSISGNLQRIKEGLNKHVSSLWNCVRQMNGTLRSHSRDISGLKNSVQQFYSHVF 770
Query: 389 KDST 392
+ ST
Sbjct: 771 QIST 774
>gi|145199237 transcription elongation factor B polypeptide 3 binding
protein 1 [Homo sapiens]
Length = 1221
Score = 31.2 bits (69), Expect = 3.2
Identities = 14/43 (32%), Positives = 24/43 (55%)
Query: 69 KPLLNDGQFRKTEQFCKSFENGIGKELHEQLVALDKQNKHTSY 111
K + DG+ + E F K+FE + + H + ALD + +T+Y
Sbjct: 1030 KQHVQDGRKERLEGFVKTFEKELSGDTHPGIYALDCEMSYTTY 1072
>gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo
sapiens]
Length = 399
Score = 30.4 bits (67), Expect = 5.4
Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 4/58 (6%)
Query: 379 AVLRFFNEVFKDSTQTPAVTPQSQPA---TTDSTVTVQKLNFELTDALKTGITAAKEK 433
+VL E+ KD ++ V+ Q QPA TTD +V + E+ D K+G ++++K
Sbjct: 195 SVLNIATEI-KDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKK 251
>gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 1430
Score = 30.4 bits (67), Expect = 5.4
Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 4/58 (6%)
Query: 379 AVLRFFNEVFKDSTQTPAVTPQSQPA---TTDSTVTVQKLNFELTDALKTGITAAKEK 433
+VL E+ KD ++ V+ Q QPA TTD +V + E+ D K+G ++++K
Sbjct: 451 SVLNIATEI-KDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKK 507
>gi|6912650 semaphorin 3E [Homo sapiens]
Length = 775
Score = 30.4 bits (67), Expect = 5.4
Identities = 21/81 (25%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Query: 423 LKTGITAAKEKFDATMKTLTIDCVQFQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQT 482
L GI + T ++L + F + G+E K++ + D V ++ + FLR +
Sbjct: 589 LAYGIENNSTLLECTPRSLQAKVIWFVQKGRETRKEEVKTDDRVVKMDLGLLFLRLHKSD 648
Query: 483 VATYESCSTAAFKHGRTETIR 503
TY C T +H T+R
Sbjct: 649 AGTY-FCQTV--EHSFVHTVR 666
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,757,085
Number of Sequences: 37866
Number of extensions: 1212654
Number of successful extensions: 3954
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 3808
Number of HSP's gapped (non-prelim): 50
length of query: 658
length of database: 18,247,518
effective HSP length: 109
effective length of query: 549
effective length of database: 14,120,124
effective search space: 7751948076
effective search space used: 7751948076
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.