Guide to the Human Genome
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Search of human proteins with 38348340

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38348340 diacylglycerol O-acyltransferase 2-like 6 [Homo
sapiens]
         (337 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38348340 diacylglycerol O-acyltransferase 2-like 6 [Homo sapi...   698   0.0  
gi|51317389 wax synthase 2 [Homo sapiens]                             373   e-103
gi|26024197 diacylglycerol O-acyltransferase 2 [Homo sapiens]         368   e-102
gi|61888902 wax synthase 1 [Homo sapiens]                             360   1e-99
gi|30039700 monoacylglycerol O-acyltransferase 3 [Homo sapiens]       325   4e-89
gi|148746191 monoacylglycerol O-acyltransferase 1 [Homo sapiens]      317   1e-86
gi|37537527 monoacylglycerol O-acyltransferase 2 [Homo sapiens]       285   4e-77
gi|4507689 transient receptor potential cation channel, subfamil...    30   2.3  
gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens]           28   8.9  
gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]            28   8.9  

>gi|38348340 diacylglycerol O-acyltransferase 2-like 6 [Homo
           sapiens]
          Length = 337

 Score =  698 bits (1802), Expect = 0.0
 Identities = 337/337 (100%), Positives = 337/337 (100%)

Query: 1   MAFFSRLNLQEGLQTFFVLQWIPVYIFLGAIPILLIPYFLLFSKFWPLAVLSLAWLTYDW 60
           MAFFSRLNLQEGLQTFFVLQWIPVYIFLGAIPILLIPYFLLFSKFWPLAVLSLAWLTYDW
Sbjct: 1   MAFFSRLNLQEGLQTFFVLQWIPVYIFLGAIPILLIPYFLLFSKFWPLAVLSLAWLTYDW 60

Query: 61  NTHSQGGRRSAWVRNWTLWKYFRNYFPVKLVKTHDLSPKHNYIIANHPHGILSFGVFINF 120
           NTHSQGGRRSAWVRNWTLWKYFRNYFPVKLVKTHDLSPKHNYIIANHPHGILSFGVFINF
Sbjct: 61  NTHSQGGRRSAWVRNWTLWKYFRNYFPVKLVKTHDLSPKHNYIIANHPHGILSFGVFINF 120

Query: 121 ATEATGIARIFPSITPFVGTLERIFWIPIVREYVMSMGVCPVSSSALKYLLTQKGSGNAV 180
           ATEATGIARIFPSITPFVGTLERIFWIPIVREYVMSMGVCPVSSSALKYLLTQKGSGNAV
Sbjct: 121 ATEATGIARIFPSITPFVGTLERIFWIPIVREYVMSMGVCPVSSSALKYLLTQKGSGNAV 180

Query: 181 VIVVGGAAEALLCRPGASTLFLKQRKGFVKMALQTGAYLVPSYSFGENEVFNQETFPEGT 240
           VIVVGGAAEALLCRPGASTLFLKQRKGFVKMALQTGAYLVPSYSFGENEVFNQETFPEGT
Sbjct: 181 VIVVGGAAEALLCRPGASTLFLKQRKGFVKMALQTGAYLVPSYSFGENEVFNQETFPEGT 240

Query: 241 WLRLFQKTFQDTFKKILGLNFCTFHGRGFTRGSWGFLPFNRPITTVVGEPLPIPRIKRPN 300
           WLRLFQKTFQDTFKKILGLNFCTFHGRGFTRGSWGFLPFNRPITTVVGEPLPIPRIKRPN
Sbjct: 241 WLRLFQKTFQDTFKKILGLNFCTFHGRGFTRGSWGFLPFNRPITTVVGEPLPIPRIKRPN 300

Query: 301 QKTVDKYHALYISALRKLFDQHKVEYGLPETQELTIT 337
           QKTVDKYHALYISALRKLFDQHKVEYGLPETQELTIT
Sbjct: 301 QKTVDKYHALYISALRKLFDQHKVEYGLPETQELTIT 337


>gi|51317389 wax synthase 2 [Homo sapiens]
          Length = 333

 Score =  373 bits (957), Expect = e-103
 Identities = 170/332 (51%), Positives = 236/332 (71%), Gaps = 4/332 (1%)

Query: 5   SRLNLQEGLQTFFVLQWIPVYIFLGAIPILLIPYFLLFSKFWPLAVLSLAWLTYDWNTHS 64
           S+ +L+  L  F V QW    + +    I +  Y ++F+ +WP+ VL L WL +DW T  
Sbjct: 5   SKKDLKTALDVFAVFQWSFSALLITTTVIAVNLYLVVFTPYWPVTVLILTWLAFDWKTPQ 64

Query: 65  QGGRRSAWVRNWTLWKYFRNYFPVKLVKTHDLSPKHNYIIANHPHGILSFGVFINFATEA 124
           +GGRR   VR+W LWK++ +YFP+KL+KTHD+ P  NYI+  HPHG+ + G F +FATEA
Sbjct: 65  RGGRRFTCVRHWRLWKHYSDYFPLKLLKTHDICPSRNYILVCHPHGLFAHGWFGHFATEA 124

Query: 125 TGIARIFPSITPFVGTLERIFWIPIVREYVMSMGVCPVSSSALKYLLTQKGSGNAVVIVV 184
           +G ++IFP ITP++ TL   FW+P +REYVMS G C VS S++ +LLT KG+GN V++V+
Sbjct: 125 SGFSKIFPGITPYILTLGAFFWMPFLREYVMSTGACSVSRSSIDFLLTHKGTGNMVIVVI 184

Query: 185 GGAAEALLCRPGASTLFLKQRKGFVKMALQTGAYLVPSYSFGENEVFNQETFPEGTWLRL 244
           GG AE     PG+STL LK R GFV+MALQ G  L+P+Y+FGE ++++Q  F  G ++  
Sbjct: 185 GGLAECRYSLPGSSTLVLKNRSGFVRMALQHGVPLIPAYAFGETDLYDQHIFTPGGFVNR 244

Query: 245 FQKTFQDTFKKILGLNFCTFHGRGFTRGSWGFLPFNRPITTVVGEPLPIPRIKRPNQKTV 304
           FQK FQ     ++ +  C F+GRGFT+ SWG LP++RP+TT+VGEPLP+P+I+ P+Q+ V
Sbjct: 245 FQKWFQ----SMVHIYPCAFYGRGFTKNSWGLLPYSRPVTTIVGEPLPMPKIENPSQEIV 300

Query: 305 DKYHALYISALRKLFDQHKVEYGLPETQELTI 336
            KYH LYI ALRKLFDQHK ++G+ ETQEL I
Sbjct: 301 AKYHTLYIDALRKLFDQHKTKFGISETQELEI 332


>gi|26024197 diacylglycerol O-acyltransferase 2 [Homo sapiens]
          Length = 388

 Score =  368 bits (945), Expect = e-102
 Identities = 171/337 (50%), Positives = 238/337 (70%), Gaps = 6/337 (1%)

Query: 1   MAFFSRLNLQEGLQTFFVLQWIPVYIFLGAIPILLIPYFLLFSKFWPLAVLSLAWLTYDW 60
           + + +R  +++ LQ   VLQW+  ++ LG     ++ Y +  +  W +AVL   WL +DW
Sbjct: 56  VTWLNRSKVEKQLQVISVLQWVLSFLVLGVACSAILMY-IFCTDCWLIAVLYFTWLVFDW 114

Query: 61  NTHSQGGRRSAWVRNWTLWKYFRNYFPVKLVKTHDLSPKHNYIIANHPHGILSFGVFINF 120
           NT  +GGRRS WVRNW +W+YFR+YFP++LVKTH+L    NYI   HPHGI+  G F NF
Sbjct: 115 NTPKKGGRRSQWVRNWAVWRYFRDYFPIQLVKTHNLLTTRNYIFGYHPHGIMGLGAFCNF 174

Query: 121 ATEATGIARIFPSITPFVGTLERIFWIPIVREYVMSMGVCPVSSSALKYLLTQKGSGNAV 180
           +TEAT +++ FP I P++ TL   F +P++REY+MS G+CPVS   + YLL++ GSGNA+
Sbjct: 175 STEATEVSKKFPGIRPYLATLAGNFRMPVLREYLMSGGICPVSRDTIDYLLSKNGSGNAI 234

Query: 181 VIVVGGAAEALLCRPGASTLFLKQRKGFVKMALQTGAYLVPSYSFGENEVFNQETFPEGT 240
           +IVVGGAAE+L   PG + + L+ RKGFVK+AL+ GA LVP YSFGENEV+ Q  F EG+
Sbjct: 235 IIVVGGAAESLSSMPGKNAVTLRNRKGFVKLALRHGADLVPIYSFGENEVYKQVIFEEGS 294

Query: 241 WLRLFQKTFQDTFKKILGLNFCTFHGRG-FTRGSWGFLPFNRPITTVVGEPLPIPRIKRP 299
           W R  QK FQ    K +G   C FHGRG F+  +WG +P+++PITTVVGEP+ IP+++ P
Sbjct: 295 WGRWVQKKFQ----KYIGFAPCIFHGRGLFSSDTWGLVPYSKPITTVVGEPITIPKLEHP 350

Query: 300 NQKTVDKYHALYISALRKLFDQHKVEYGLPETQELTI 336
            Q+ +D YH +Y+ AL KLFD+HK ++GLPET+ L +
Sbjct: 351 TQQDIDLYHTMYMEALVKLFDKHKTKFGLPETEVLEV 387


>gi|61888902 wax synthase 1 [Homo sapiens]
          Length = 328

 Score =  360 bits (923), Expect = 1e-99
 Identities = 177/323 (54%), Positives = 232/323 (71%), Gaps = 10/323 (3%)

Query: 14  QTFFVLQWIPVYIFLGAIPILLIPYF--LLFSKFWPLAVLSLAWLTYDWNTHSQGGRRSA 71
           Q+  +LQW   Y+   AI  +L P F  LLF+  WPL VL  AWL  DW T  +GGRRSA
Sbjct: 11  QSLMLLQWPLSYL---AIFWILQPLFVYLLFTSLWPLPVLYFAWLFLDWKTPERGGRRSA 67

Query: 72  WVRNWTLWKYFRNYFPVKLVKTHDLSPKHNYIIANHPHGILSFGVFINFATEATGIARIF 131
           WVRNW +W + R+YFP+ ++KT DLSP+HNY++  HPHG+L+FG F NF TEATG ++ F
Sbjct: 68  WVRNWCVWTHIRDYFPITILKTKDLSPEHNYLMGVHPHGLLTFGAFCNFCTEATGFSKTF 127

Query: 132 PSITPFVGTLERIFWIPIVREYVMSMGVCPVSSSALKYLLTQKGSGNAVVIVVGGAAEAL 191
           P ITP + TL   F IP VREY+M+ GVC VS  A+ YLL+  G+GN V IVVGG  EAL
Sbjct: 128 PGITPHLATLSWFFKIPFVREYLMAKGVCSVSQPAINYLLSH-GTGNLVGIVVGGVGEAL 186

Query: 192 LCRPGASTLFLKQRKGFVKMALQTGAYLVPSYSFGENEVFNQETFPEGTWLRLFQKTFQD 251
              P  +TL L++RKGFV+ ALQ GA+LVP+++FGE EV++Q  F + +  R+++  FQ 
Sbjct: 187 QSVPNTTTLILQKRKGFVRTALQHGAHLVPTFTFGETEVYDQVLFHKDS--RMYK--FQS 242

Query: 252 TFKKILGLNFCTFHGRGFTRGSWGFLPFNRPITTVVGEPLPIPRIKRPNQKTVDKYHALY 311
            F++I G   C F+G+ F +GS G LP++RPI TVVGEPLP+P+I++P+Q+ VDKYHALY
Sbjct: 243 CFRRIFGFYCCVFYGQSFCQGSTGLLPYSRPIVTVVGEPLPLPQIEKPSQEMVDKYHALY 302

Query: 312 ISALRKLFDQHKVEYGLPETQEL 334
           + AL KLFDQHK  YG  ETQ+L
Sbjct: 303 MDALHKLFDQHKTHYGCSETQKL 325


>gi|30039700 monoacylglycerol O-acyltransferase 3 [Homo sapiens]
          Length = 341

 Score =  325 bits (833), Expect = 4e-89
 Identities = 154/327 (47%), Positives = 223/327 (68%), Gaps = 6/327 (1%)

Query: 10  QEGLQTFFVLQWIPVYIFLGAIPILLIPYFLLFSKFWPLAVLSLAWLTYDWNTHSQGGRR 69
           ++ L+     Q++  ++F+G    LL+ + LLF+  WP +V  L WL  DW+T +QGGRR
Sbjct: 18  KQHLEAVGAYQYVLTFLFMGPFFSLLV-FVLLFTSLWPFSVFYLVWLYVDWDTPNQGGRR 76

Query: 70  SAWVRNWTLWKYFRNYFPVKLVKTHDLSPKHNYIIANHPHGILSFGVFINFATEATGIAR 129
           S W+RN  +W+  R+Y+PVKLVKT +L P  NY++  HPHGI+  G   NF+TE+ G ++
Sbjct: 77  SEWIRNRAIWRQLRDYYPVKLVKTAELPPDRNYVLGAHPHGIMCTGFLCNFSTESNGFSQ 136

Query: 130 IFPSITPFVGTLERIFWIPIVREYVMSMGVCPVSSSALKYLLTQKGSGNAVVIVVGGAAE 189
           +FP + P++  L  +F++P+ R+Y+MS G+CPVS  +L ++L+Q   G AVVI+VGGA E
Sbjct: 137 LFPGLRPWLAVLAGLFYLPVYRDYIMSFGLCPVSRQSLDFILSQPQLGQAVVIMVGGAHE 196

Query: 190 ALLCRPGASTLFLKQRKGFVKMALQTGAYLVPSYSFGENEVFNQETFPEGTWLRLFQKTF 249
           AL   PG   L L++RKGFV++AL+ GA LVP YSFGEN++F  + F  G+W    Q   
Sbjct: 197 ALYSVPGEHCLTLQKRKGFVRLALRHGASLVPVYSFGENDIFRLKAFATGSW----QHWC 252

Query: 250 QDTFKKILGLNFCTFHGRG-FTRGSWGFLPFNRPITTVVGEPLPIPRIKRPNQKTVDKYH 308
           Q TFKK++G + C F GRG F+  SWG LPF  PITTVVG P+P+P+   P ++ V+ YH
Sbjct: 253 QLTFKKLMGFSPCIFWGRGLFSATSWGLLPFAVPITTVVGRPIPVPQRLHPTEEEVNHYH 312

Query: 309 ALYISALRKLFDQHKVEYGLPETQELT 335
           ALY++AL +LF++HK   G+P +  LT
Sbjct: 313 ALYMTALEQLFEEHKESCGVPASTCLT 339


>gi|148746191 monoacylglycerol O-acyltransferase 1 [Homo sapiens]
          Length = 335

 Score =  317 bits (811), Expect = 1e-86
 Identities = 152/335 (45%), Positives = 219/335 (65%), Gaps = 7/335 (2%)

Query: 4   FSRLNLQ--EGLQTFFVLQWIPVYIFLGAIPILLIPYFLLFSKFWPLAVLSLAWLTYDWN 61
           F+ LN+Q    LQT  VLQW+  Y+ LG + I  I   L+   +  L +  L WL +DW+
Sbjct: 5   FAPLNIQLARRLQTVAVLQWVLKYLLLGPMSIG-ITVMLIIHNYLFLYIPYLMWLYFDWH 63

Query: 62  THSQGGRRSAWVRNWTLWKYFRNYFPVKLVKTHDLSPKHNYIIANHPHGILSFGVFINFA 121
           T  +GGRRS+W++NWTLWK+F++YFP+ L+KT DL P HNYI   HPHGI++ G F NF+
Sbjct: 64  TPERGGRRSSWIKNWTLWKHFKDYFPIHLIKTQDLDPSHNYIFGFHPHGIMAVGAFGNFS 123

Query: 122 TEATGIARIFPSITPFVGTLERIFWIPIVREYVMSMGVCPVSSSALKYLLTQKGSGNAVV 181
              +    +FP  T ++  L   FW P+ REYVMS+G+  VS  ++ Y+++++G GN  V
Sbjct: 124 VNYSDFKDLFPGFTSYLHVLPLWFWCPVFREYVMSVGLVSVSKKSVSYMVSKEGGGNISV 183

Query: 182 IVVGGAAEALLCRPGASTLFLKQRKGFVKMALQTGAYLVPSYSFGENEVFNQETFPEGTW 241
           IV+GGA E+L   PG  TLF++QRKGFVK+AL  GA LVP  SFGENE+F Q   PEG+W
Sbjct: 184 IVLGGAKESLDAHPGKFTLFIRQRKGFVKIALTHGASLVPVVSFGENELFKQTDNPEGSW 243

Query: 242 LRLFQKTFQDTFKKILGLNFCTFHGRGFTRGSWGFLPFNRPITTVVGEPLPIPRIKRPNQ 301
           +R    T Q+  +KI+G     FH RG  + ++G + + + I TVVG P+P+ +   P Q
Sbjct: 244 IR----TVQNKLQKIMGFALPLFHARGVFQYNFGLMTYRKAIHTVVGRPIPVRQTLNPTQ 299

Query: 302 KTVDKYHALYISALRKLFDQHKVEYGLPETQELTI 336
           + +++ H  Y+  LRKLF++HK +YG+PE + L +
Sbjct: 300 EQIEELHQTYMEELRKLFEEHKGKYGIPEHETLVL 334


>gi|37537527 monoacylglycerol O-acyltransferase 2 [Homo sapiens]
          Length = 334

 Score =  285 bits (729), Expect = 4e-77
 Identities = 145/323 (44%), Positives = 202/323 (62%), Gaps = 7/323 (2%)

Query: 13  LQTFFVLQWIPVYIFLGAIPILLIPYF-LLFSKFWPLAVLSLAWLTYDWNTHSQGGRRSA 71
           LQT  VLQ+  V+ FL    I  + +  LLF++FW L VL  AW   D +   QGGR   
Sbjct: 15  LQTLAVLQF--VFSFLALAEICTVGFIALLFTRFWLLTVLYAAWWYLDRDKPRQGGRHIQ 72

Query: 72  WVRNWTLWKYFRNYFPVKLVKTHDLSPKHNYIIANHPHGILSFGVFINFATEATGIARIF 131
            +R WT+WKY ++YFP+ LVKT +L P  NYI   HPHG+L+ G F N  TE+TG + IF
Sbjct: 73  AIRCWTIWKYMKDYFPISLVKTAELDPSRNYIAGFHPHGVLAVGAFANLCTESTGFSSIF 132

Query: 132 PSITPFVGTLERIFWIPIVREYVMSMGVCPVSSSALKYLLTQKGSGNAVVIVVGGAAEAL 191
           P I P +  L   F  P  R+Y+MS G+      +  ++L +KG GN + I+VGGA EAL
Sbjct: 133 PGIRPHLMMLTLWFRAPFFRDYIMSAGLVTSEKESAAHILNRKGGGNLLGIIVGGAQEAL 192

Query: 192 LCRPGASTLFLKQRKGFVKMALQTGAYLVPSYSFGENEVFNQETFPEGTWLRLFQKTFQD 251
             RPG+ TL L+ RKGFV++AL  GA LVP +SFGEN++F+Q     G+WLR  Q   Q 
Sbjct: 193 DARPGSFTLLLRNRKGFVRLALTHGAPLVPIFSFGENDLFDQIPNSSGSWLRYIQNRLQ- 251

Query: 252 TFKKILGLNFCTFHGRGFTRGSWGFLPFNRPITTVVGEPLPIPRIKRPNQKTVDKYHALY 311
              KI+G++   FHGRG  + S+G +P+ RPITTVVG+P+ + +   P+++ V++ H  Y
Sbjct: 252 ---KIMGISLPLFHGRGVFQYSFGLIPYRRPITTVVGKPIEVQKTLHPSEEEVNQLHQRY 308

Query: 312 ISALRKLFDQHKVEYGLPETQEL 334
           I  L  LF+ HK+++ +P  Q L
Sbjct: 309 IKELCNLFEAHKLKFNIPADQHL 331


>gi|4507689 transient receptor potential cation channel, subfamily
           M, member 2 [Homo sapiens]
          Length = 1503

 Score = 30.4 bits (67), Expect = 2.3
 Identities = 23/73 (31%), Positives = 40/73 (54%), Gaps = 7/73 (9%)

Query: 150 VREYVMSMGVCPVSSSALKYLLTQKGSGNA--VVIVVGGAAEALLCRPGASTLFLKQRKG 207
           V++YV      P  SS + +L+TQ    +   ++I V G A+    +P   ++F   R+G
Sbjct: 139 VKKYVRVSQDTP--SSVIYHLMTQHWGLDVPNLLISVTGGAKNFNMKPRLKSIF---RRG 193

Query: 208 FVKMALQTGAYLV 220
            VK+A  TGA+++
Sbjct: 194 LVKVAQTTGAWII 206


>gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens]
          Length = 1251

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 3/60 (5%)

Query: 112  LSFGVFINFATEATGIARIFPSITPFVGTLERIFWIPIV-REYVMSMGVCPVSSSALKYL 170
            L FG+  +F   + GI  +FPS   F GT       P +    ++++ VC +   A+++L
Sbjct: 1109 LYFGIMFDF--HSAGIHVLFPSAFQFTGTASNALRQPYIWLTIILTVAVCLLPVVAIRFL 1166


>gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]
          Length = 4265

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 15/37 (40%), Positives = 19/37 (51%), Gaps = 1/37 (2%)

Query: 253  FKKILGLNFCTFHGRGFTRGSWGFLPFNRPITTVVGE 289
            FK +L L+ C FHG    R  +G L FN P     G+
Sbjct: 3814 FKSLL-LSLCLFHGNALERRKFGPLGFNIPYEFTDGD 3849


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.142    0.460 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,842,373
Number of Sequences: 37866
Number of extensions: 566465
Number of successful extensions: 1233
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1212
Number of HSP's gapped (non-prelim): 12
length of query: 337
length of database: 18,247,518
effective HSP length: 103
effective length of query: 234
effective length of database: 14,347,320
effective search space: 3357272880
effective search space used: 3357272880
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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